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Nagatsugi Fumi  永次 史

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NAGATSUGI Fumi  永次 史

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Researcher Number 90208025
Other IDs
External Links
Affiliation (Current) 2022: 東北大学, 多元物質科学研究所, 教授
Affiliation (based on the past Project Information) *help 2006 – 2022: Tohoku University, Institute of Multidiciplinary Research for Advanced Materials, Professor, 多元物質科学研究所, 教授
2013: 東北大学, 多元物質科学研究, 教授
2010: 東北大学, 多元物質科学研究, 教授
2008: 東北大学, 多元物質化学研究所, 教授
2006: 東北大学, 多次元物質化学研究所, 教授 … More
2003 – 2005: 九州大学, 薬学研究院, 助教授
2002: Faculty of Pharmaceutical Sciences, Assistant Prof., 薬学研究院, 助手
2000 – 2001: 九州大学, 大学院・薬学研究院, 助手
2000: Graduate School of Pharmacetical Sciences, KYUSHU UNIVERSITY Assistant Professor, 薬学研究院, 助手
1999: 九州大学, 大学院・薬学研究科, 助手
1999: 九州大学, 薬学研究科, 助手
1996 – 1998: 九州大学, 薬学部, 助手 Less
Review Section/Research Field
Principal Investigator
Science and Engineering / Chemistry related to living body / Radiation science / Chemical pharmacy / Bio-related chemistry / Bioorganic chemistry / Drug development chemistry / Basic Section 37010:Bio-related chemistry / Medium-sized Section 37:Biomolecular chemistry and related fields
Except Principal Investigator
Chemical pharmacy / Drug development chemistry / Chemical pharmacy
Keywords
Principal Investigator
クロスリンク / クロスリンク反応 / 2-アミノ-6-ビニルプリン / アンチセンス / FRET / アルキル化反応 / RNA高次構造 / ハイブリダイゼーション / 遺伝子 / 薬物放出システム … More / クリックケミストリー / クロスリンク剤 / 反応性オリゴマーDNA / 2-amino-6-vinyl purine / ハイブリッド形成 / オリゴヌクレオチド / ペプチド / DNA高次構造 / 核酸・蛋白質・糖化学 / オリゴDNA / In Cell Chemistry / RNA標的 / 遺伝子発現制御 / アルキル化 / 塩基欠損部位 / 2本鎖DNA / 疎水空間 / 核酸高次構造 / 核酸 / RNA / 高次構造 / 架橋反応 / 反応性核酸 / ゲノム標的化学 / 化学的点変異誘導 / antisense / reactive nucleic acids / genome targeted chemistry / point mutation by chemical method / 大規模解析 / アンチセンス法 / 標識DNAオリゴマー / アンチセンスDNA / 2-アミノ-6-ビニルグアノシン / ^<125>I標識DNAオリゴマー / アンチジーン / 標識オリゴマーDNA / マルチ制御 / 反応性オリゴDNA / 癌 / 遺伝子配列特異的薬物放出システム / ハイブリッド形成活性化 / 遺伝子検出システム / DNA / インターカレーター / コンビケム / ランダムスクリーニング / ペプチド核酸 / インベージョン / ライブラリー / 2本鎖DNA結合分子 / コンビナトリアルケミストリー / miRNA / インテリジェント核酸 / 生体関連物質 / 核酸化学 / 電子移動 / 変異誘導 / 光電子移動 / アントラキノン / 光増感剤 / 疎水場 / バルジ構造 / ヘアピン構造 / ２本鎖DNA / 蛍光標識 / 選択的アルキル化反応 / ペンタペプチド / 塩基欠失部位 / 高次構造RNA / ヘキスト / 選択的化学反応 / 発現制御 / 低分子プローブ / 2-アミノ6-ビニルプリン / 3本鎖形成 / 点変異誘起 / 2-amino-6-vinilpurine / 2-アミノ-6ビニルプリン / ドラッグデリバリーシステム / ダブル活性化構造 / 2-アミノー6ビニルプリン / ポストモディフィケーション / 2-amino-6-vinyopurine / double acativation / drug delivery system / 蛍光 / 細胞内検出 / マスキング剤 / Cross-Link / Hybridization / Drug releasing system / Fluorescence / Gene / Detection in Cells / 逆転写阻害核酸系薬剤 / 薬剤耐性機構 / HIV治療薬 / ヌクレオチド除去反応 / ウイルスRNA / 中分子 / グアニン４重鎖 / ノンコーディングRNA / 機能性中分子 / RNA結合分子 / グアニン4重鎖 / G-カルテット構造 / 反応性プローブ / RNA 高次構造 / RNA 結合分子 / ハイブリッド型核酸標的医薬 / RNA標的創薬 / 選択的アルキル化 / 反応性分子 / 大規模解析法 / 蛍光指示薬競合置換アッセイ / バーコードマイクロアレイ / ハイスループット検索システム / RNA結合蛍光分子 / 結合分子 / 蛍光性分子 … More
Except Principal Investigator
ゲノム標的分子 / 機能性核酸 / 反応性分子 / インテリジェント核酸 / ナノ医薬 / インテリジェント / 有機化学 / インテリジェント人工核酸 / マイナーグループバインダー / アンチセンス / アンチジーン / 3本鎖DNA / 核酸医薬 / 薬物送達 / ナノメディスン / 2型糖尿病 / 疾患モデルマウス / ２型糖尿病 / ミトコンドリア / 機能性人工核酸 / 配列選択性 / DNA配列認識 / 新規リガンド / ビステトラヒドロフラン / ビスフラン / ビスピロール / DNA結合 / COMBINATORIAL CHEMISTRY / SOLID-STATE LIBRARY / PEPTIDE LIBRARY / DUPLEX DNA / DNA-BINDING MOLECULES / HYDROPHOBIC AMINO ACIDS Less

  • Research Projects

    (23 results)

  • Research Products

    (904 results)

  • Co-Researchers

    (30 People)

  •  RNA標的創薬を志向したRNA結合分子探索システムの構築Principal Investigator

    • Principal Investigator
      永次 史
    • Project Period (FY)
      2021 – 2022
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 37:Biomolecular chemistry and related fields
    • Research Institution
      Tohoku University

  •  Development of the method for large-scale analysis of the reactive molecules to RNA higher-ordered structurePrincipal Investigator

    • Principal Investigator
      永次 史
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 37010:Bio-related chemistry
    • Research Institution
      Tohoku University

  •  The new strategy for the development of the inhibitor of reverse transcriptasePrincipal Investigator

    • Principal Investigator
      Nagatsugi Fumi
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Drug development chemistry
    • Research Institution
      Tohoku University

  •  Development for the functional middle size molecules to the high ordered nucleic acidsstructurePrincipal Investigator

    • Principal Investigator
      Nagatsugi Fumi
    • Project Period (FY)
      2015 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Science and Engineering
    • Research Institution
      Tohoku University

  •  遺伝子を標的とした新規機能性低分子プロ－ブの開発Principal Investigator

    • Principal Investigator
      永次 史
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Science and Engineering
    • Research Institution
      Tohoku University

  •  Development of the strategy for the site-directed modification in hydrophobic pocket of DNA for the control of gene expressionPrincipal Investigator

    • Principal Investigator
      Nagatsugi Fumi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Bio-related chemistry
    • Research Institution
      Tohoku University

  •  遺伝子を標的とした新規機能性低分子プローブの開発Principal Investigator

    • Principal Investigator
      永次 史
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Science and Engineering
    • Research Institution
      Tohoku University

  •  Development of the strategy for inducing the selective point mutation by regulation of the electron transfer in the duplex DNAPrincipal Investigator

    • Principal Investigator
      NAGATSUGI Fumi
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Chemical pharmacy
    • Research Institution
      Tohoku University

  •  Study on the innovative molecular-targeting medicine based on the nano-DDS encapsulating intelligent artificial oligonucleotides

    • Principal Investigator
      SASAKI Shigeki
    • Project Period (FY)
      2009 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Drug development chemistry
    • Research Institution
      Kyushu University

  •  Development of the Functional Molecules for Genome Targeting ChemistryPrincipal Investigator

    • Principal Investigator
      NAGATSUGI Fumi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Chemistry related to living body
    • Research Institution
      Tohoku University

  •  細胞内におけるDNA高次構造認識分子の開発Principal Investigator

    • Principal Investigator
      永次 史
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Science and Engineering
    • Research Institution
      Tohoku University

  •  Application of the Activated Reaction by Hybridization to Target Genes for the Regulation of Gene Expression in CellsPrincipal Investigator

    • Principal Investigator
      NAGATSUGI Fumi
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Chemistry related to living body
    • Research Institution
      Tohoku University

  •  クリックケミストリーを応用した2本鎖DNA結合分子の新規検索法の開発Principal Investigator

    • Principal Investigator
      永次 史
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Chemical pharmacy
    • Research Institution
      Tohoku University

  •  ハイブリッド形成により細胞情報伝達システムをマルチ制御する機能性分子の開発Principal Investigator

    • Principal Investigator
      永次 史
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Science and Engineering
    • Research Institution
      Tohoku University

  •  ハイブリッド形成により細胞情報伝達システムをマルチ制御する機能性分子の開発Principal Investigator

    • Principal Investigator
      永次 史
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Science and Engineering
    • Research Institution
      Kyushu University

  •  Development of Genome-Targeting Molecules with Ability of Chemical Reactivity and Application to Intelligent Nano-Medicine

    • Principal Investigator
      SASAKI Shigeki
    • Project Period (FY)
      2005 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Chemical pharmacy
    • Research Institution
      Kyushu University

  •  Development of the Intelligent Nucleic Acids having Multi Regulation Activity Triggered by HybridizationPrincipal Investigator

    • Principal Investigator
      NAGATSUGI Fumi
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Chemistry related to living body
    • Research Institution
      Tohoku University
      Kyushu University

  •  The Development of the Method to Introduce the Selective Point Mutation using the Reactive OligonucleotidesPrincipal Investigator

    • Principal Investigator
      NAGATSUGI Fumi
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Chemistry related to living body
    • Research Institution
      KYUSHU UNIVERSITY

  •  The Development of the Novel Reactive Nucleobases to the Duplex DNAPrincipal Investigator

    • Principal Investigator
      NAGATSUGI Fumi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Bioorganic chemistry
    • Research Institution
      Kyushu University

  •  新規クロスリンク剤を組み込んだペプチド核酸のがん治療及び診断薬への展開Principal Investigator

    • Principal Investigator
      永次 史
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Radiation science
    • Research Institution
      Kyushu University

  •  Development of the New Recognition Molecules of DNA Sequences Based on the GC- and AT-Selective Ligands

    • Principal Investigator
      SASAKI Shigeki
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Chemical pharmacy
    • Research Institution
      KYUSHU UNIVERSITY

  •  遺伝子を標的とする新しい癌診断及び癌治療法の開発Principal Investigator

    • Principal Investigator
      永次 史
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Radiation science
    • Research Institution
      Kyushu University

  •  効率的なアンチセンス法による新しい癌診断薬の開発Principal Investigator

    • Principal Investigator
      永次 史
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Radiation science
    • Research Institution
      Kyushu University

All 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation Book Patent

  • [Book] Middle Nolecular Strategy2021
    • Author(s)
      Fumi Nagatsugi
    • Total Pages
      357
    • Publisher
      Springer
    • ISBN
      9789811624575
    • Data Source
      KAKENHI-PROJECT-21K19038

  • [Book] Middle Nolecular Strategy2021
    • Author(s)
      Fumi Nagatsugi, Kazumitsu Onizuka
    • Total Pages
      357
    • Publisher
      Springer
    • ISBN
      9789811624575
    • Data Source
      KAKENHI-PROJECT-20H02855

  • [Book] Molecular Design for Specific Recognition and Reaction in Genome-Targeting Chemistry, Frontiers in Organic Chemistry2005
    • Author(s)
      S.Sasaki, F.Nagatsugi
    • Publisher
      Bentham Science Publishers
    • Data Source
      KAKENHI-PROJECT-17035063

  • [Book] Molecular Design for Specific Recognition and Reaction in Genome-Targeting Chemistry, Frontiers in Organic Chemistry2005
    • Author(s)
      S.Sasaki, F.Nagatsugi
    • Publisher
      Bentham Science Publishers
    • Data Source
      KAKENHI-PROJECT-17209001

  • [Book] Molecular Design for Specific Recognition and Reaction in Genome-Targeting Chemistry, Frontiers in Organic Chemistry2005
    • Author(s)
      S.Sasaki, F.Nagatsugi
    • Publisher
      Bentham Science Publisherss
    • Data Source
      KAKENHI-PROJECT-17550158

  • [Journal Article] Selective and stable base pairing by alkynylated nucleosides featuring a spatially-separated recognition interface2022
    • Author(s)
      Okamura Hidenori、Trinh Giang Hoang、Dong Zhuoxin、Masaki Yoshiaki、Seio Kohji、Nagatsugi Fumi
    • Journal Title

      Nucleic Acids Research

      Volume: 50 Pages: 3042-3055

    • DOI

      10.1093/nar/gkac140

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H02855, KAKENHI-PROJECT-21K19038, KAKENHI-PROJECT-21K14749

  • [Journal Article] Synthesis of Crosslinked 2′‐OMe RNA Duplexes Using 2‐Amino‐6‐Vinylpurine and Their Application for Effective Inhibition of miRNA Function2022
    • Author(s)
      Abdelhady Ahmed Mostafa、Hirano Yu、Onizuka Kazumitsu、Okamura Hidenori、Komatsu Yasuo、Nagatsugi Fumi
    • Journal Title

      Current Protocols

      Volume: 2

    • DOI

      10.1002/cpz1.386

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H02855

  • [Journal Article] Rapid Alkene?Alkene Photo-Cross-Linking on the Base-Flipping-Out Field in Duplex DNA2022
    • Author(s)
      Abdelhady Ahmed Mostafa、Onizuka Kazumitsu、Ishida Kei、Yajima Sayaka、Mano Eriko、Nagatsugi Fumi
    • Journal Title

      The Journal of Organic Chemistry

      Volume: 87 Pages: 2267-2276

    • DOI

      10.1021/acs.joc.1c01498

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-20H04762, KAKENHI-PROJECT-19H02845, KAKENHI-PROJECT-20H02855, KAKENHI-PROJECT-21K19038, KAKENHI-PROJECT-21K19323

  • [Journal Article] Selective alkylation of parallel G-quadruplex structure2021
    • Author(s)
      Onizuka Kazumitsu、Ganbold Erchissaran、Ma Yue、Sasaki Shogo、Hazemi Madoka E.、Chen Yutong、Sato Norihiro、Ozawa Mamiko、Nagasawa Kazuo、Nagatsugi Fumi
    • Journal Title

      Organic &amp; Biomolecular Chemistry

      Volume: 19 Pages: 2891-2894

    • DOI

      10.1039/d0ob02365e

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-18H04387, KAKENHI-PUBLICLY-20H04762, KAKENHI-PROJECT-19H02845, KAKENHI-PROJECT-20H02855, KAKENHI-PROJECT-20K15411, KAKENHI-PROJECT-20H02876, KAKENHI-PROJECT-20J13814

  • [Journal Article] Synthesis of crosslinked 2′-OMe RNA duplexes and their application for effective inhibition of miRNA function2021
    • Author(s)
      Abdelhady Ahmed Mostafa、Hirano Yu、Onizuka Kazumitsu、Okamura Hidenori、Komatsu Yasuo、Nagatsugi Fumi
    • Journal Title

      Bioorganic & Medicinal Chemistry Letters

      Volume: 48 Pages: 128257-128257

    • DOI

      10.1016/j.bmcl.2021.128257

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H03372, KAKENHI-PROJECT-20H02855, KAKENHI-PROJECT-21K05123, KAKENHI-PROJECT-21K19038

  • [Journal Article] Liquid-like droplet formation by tumor suppressor p53 induced by multivalent electrostatic interactions between two disordered domains2020
    • Author(s)
      Kamagata Kiyoto、Kanbayashi Saori、Honda Masaya、Itoh Yuji、Takahashi Hiroto、Kameda Tomoshi、Nagatsugi Fumi、Takahashi Satoshi
    • Journal Title

      Scientific Reports

      Volume: 10 Pages: 580-580

    • DOI

      10.1038/s41598-020-57521-w

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-15H05838, KAKENHI-PROJECT-16KK0157, KAKENHI-PROJECT-18H02382

  • [Journal Article] DNAの狙った構造だけを化学修飾する！2020
    • Author(s)
      永次　史、鬼塚　和光
    • Journal Title

      化学

      Volume: 75 Pages: 52-56

    • Open Access
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Journal Article] Functional G-Quadruplex Binding Molecules2020
    • Author(s)
      Nagatsugi Fumi、Onizuka Kazumitsu
    • Journal Title

      Chemistry Letters

      Volume: 49 Issue: 7 Pages: 771-780

    • DOI

      10.1246/cl.200214

    • NAID

      130007872516

    • ISSN
      0366-7022, 1348-0715
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-20H04762, KAKENHI-PROJECT-19H02845, KAKENHI-PROJECT-20H02855

  • [Journal Article] Design of the Crosslinking Reactions for Nucleic Acids-Binding Protein and Evaluation of the Reactivity2020
    • Author(s)
      Odaira Kenta、Yamada Ken、Ishiyama Shogo、Okamura Hidenori、Nagatsugi Fumi
    • Journal Title

      Applied Sciences

      Volume: 10 Pages: 7709-7709

    • DOI

      10.3390/app10217709

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H02855

  • [Journal Article] Synthesis of RNA Crosslinking Oligonucleotides Modified with 2‐Amino‐7‐Deaza‐7‐Propynyl‐6‐Vinylpurine2019
    • Author(s)
      Yamada Ken、Abe Yusuke、Nagatsugi Fumi
    • Journal Title

      Current Protocols in Nucleic Acid Chemistry

      Volume: 76

    • DOI

      10.1002/cpnc.79

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Journal Article] Development of the binding molecules for the RNA higher-order structures based on the guanine-recognition by the G-clamp2019
    • Author(s)
      Murase Hirotaka、Nagatsugi Fumi
    • Journal Title

      Bioorganic & Medicinal Chemistry Letters

      Volume: 29 Pages: 1320-1324

    • DOI

      10.1016/j.bmcl.2019.03.052

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K14330, KAKENHI-PLANNED-15H05838

  • [Journal Article] Alkyne?Alkyne Photo-cross-linking on the Flipping-out Field2019
    • Author(s)
      Onizuka Kazumitsu、Ishida Kei、Mano Eriko、Nagatsugi Fumi
    • Journal Title

      Organic Letters

      Volume: 21 Pages: 2833-2837

    • DOI

      10.1021/acs.orglett.9b00817

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K08153, KAKENHI-PLANNED-15H05838

  • [Journal Article] Reactive OFF-ON type alkylating agents for higher-ordered structures of nucleic acids2019
    • Author(s)
      Onizuka Kazumitsu、Hazemi Madoka E、Sato Norihiro、Tsuji Gen-ichiro、Ishikawa Shunya、Ozawa Mamiko、Tanno Kousuke、Yamada Ken、Nagatsugi Fumi
    • Journal Title

      Nucleic Acids Research

      Volume: 47 Pages: 6578-6589

    • DOI

      10.1093/nar/gkz512

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-15H05838, KAKENHI-PROJECT-19H02845

  • [Journal Article] Synthesis and Properties of 2′-OMe-RNAs Modified with Cross-Linkable 7-Deazaguanosine Derivatives2018
    • Author(s)
      Yamada Ken、Abe Yusuke、Murase Hirotaka、Ida Yuta、Hagihara Shinya、Nagatsugi Fumi
    • Journal Title

      The Journal of Organic Chemistry

      Volume: 83 Pages: 8851-8862

    • DOI

      10.1021/acs.joc.8b01002

    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Journal Article] Structural optimization of pseudorotaxane-forming oligonucleotides for efficient and stable complex formation2018
    • Author(s)
      Onizuka Kazumitsu、Miyashita Takuya、Chikuni Tomoko、Ozawa Mamiko、Abe Hiroshi、Nagatsugi Fumi
    • Journal Title

      Nucleic Acids Research

      Volume: 46 Pages: 8710-8719

    • DOI

      10.1093/nar/gky744

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-15H05838, KAKENHI-PROJECT-16KT0052, KAKENHI-PROJECT-16K08153

  • [Journal Article] Selective alkylation of T?T mismatched DNA using vinyldiaminotriazine?acridine conjugate2018
    • Author(s)
      Onizuka Kazumitsu、Usami Akira、Yamaoki Yudai、Kobayashi Tomohito、Hazemi Madoka E、Chikuni Tomoko、Sato Norihiro、Sasaki Kaname、Katahira Masato、Nagatsugi Fumi
    • Journal Title

      Nucleic Acids Research

      Volume: 46 Pages: 1059-1068

    • DOI

      10.1093/nar/gkx1278

    • NAID

      120006466620

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08153, KAKENHI-PROJECT-17K14515, KAKENHI-PLANNED-15H05838

  • [Journal Article] Alkylating probes for the G-quadruplex structure and evaluation of the properties of the alkylated G-quadruplex DNA2018
    • Author(s)
      Sato Norihiro、Takahashi Shuntaro、Tateishi-Karimata Hisae、Hazemi Madoka E.、Chikuni Tomoko、Onizuka Kazumitsu、Sugimoto Naoki、Nagatsugi Fumi
    • Journal Title

      Organic & Biomolecular Chemistry

      Volume: 16 Pages: 1436-1441

    • DOI

      10.1039/c7ob03179c

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K08153, KAKENHI-PROJECT-17K01968, KAKENHI-PROJECT-17K05941, KAKENHI-PLANNED-15H05838, KAKENHI-PLANNED-17H06351, KAKENHI-PROJECT-16H02283, KAKENHI-PROJECT-16K14041

  • [Journal Article] Vinyldiaminotriazine-acridine conjugate as G-quadruplex alkylating agent2018
    • Author(s)
      Hazemi Madoka E.、Onizuka Kazumitsu、Kobayashi Tomohito、Usami Akira、Sato Norihiro、Nagatsugi Fumi
    • Journal Title

      Bioorganic & Medicinal Chemistry

      Volume: 26 Pages: 3551-3558

    • DOI

      10.1016/j.bmc.2018.05.030

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-15H05838, KAKENHI-PROJECT-16K08153

  • [Journal Article] Pseudorotaxane formation via the slippage process with chemically-cyclized oligonucleotide2017
    • Author(s)
      Kazumitsu Onizuka, Tomoko Chikuni, Takuya Amemiya, Takuya Miyashita, Kyoko Onizuka, Hiroshi Abe, Fumi Nagatsugi
    • Journal Title

      Nucleic Acids Research

      Volume: 印刷中 Pages: 5036-5047

    • DOI

      10.1093/nar/gkx265

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PUBLICLY-15H00793, KAKENHI-PLANNED-15H05838, KAKENHI-PROJECT-15K14975, KAKENHI-PROJECT-16K08153

  • [Journal Article] Synthesis of native-like crosslinked duplex RNA and study of its properties2017
    • Author(s)
      Kazumitsu Onizuka, Madoka E. Hazemi, Justin M. Thomas, Leanna R. Monteleone, Ken Yamada, Shuhei Imoto, Peter Beal, Fumi Nagatsugi
    • Journal Title

      Bioorganic & Medicinal Chemistry

      Volume: 25 Pages: 2191-2191

    • DOI

      10.1016/j.bmc.2017.02.034

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-15H00793, KAKENHI-PROJECT-15K14975, KAKENHI-PROJECT-16K08153, KAKENHI-PLANNED-15H05838

  • [Journal Article] Synthesis of Water-Soluble Triazinophanes and Evaluation of Their Molecular Recognition Properties2017
    • Author(s)
      Kusano Shuhei、Konishi Sae、Ishikawa Ryuta、Sato Norihiro、Kawata Satoshi、Nagatsugi Fumi、Hayashida Osamu
    • Journal Title

      European Journal of Organic Chemistry

      Volume: 2017 Pages: 1618-1623

    • DOI

      10.1002/ejoc.201601663

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Journal Article] Synthesis and properties of cross-linkable DNA duplex using 4-amino-2-oxo-6-vinyl-1,3,5-triazine2017
    • Author(s)
      Yamada,K.; Ishiyama,S.; Onizuka,K.; Nagatsugi,F.
    • Journal Title

      Tetrahedron

      Volume: 73 Pages: 1424-1435

    • DOI

      10.1016/j.tet.2017.01.043

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-15H05838, KAKENHI-PROJECT-15K14975

  • [Journal Article] Synthesis of peptide nucleic acids (PNA) with a crosslinking agent to RNA and effective inhibition of dicer2016
    • Author(s)
      Akisawa Takuya, Yamada Ken, Nagatsugi Fumi
    • Journal Title

      Bioorganic & Medicinal Chemistry Letters

      Volume: 26 Pages: 5902-5906

    • DOI

      10.1016/j.bmcl.2016.11.002

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-15H05838, KAKENHI-PROJECT-15K14975

  • [Journal Article] Stabilization of the i-motif structure by the intra-strand cross-link formation2015
    • Author(s)
      K. Kikuta, H. Piao, J. Brazier, ,Y. Taniguchi, K.Onizuka, F. Nagatsugi, S. Sasaki
    • Journal Title

      Bioorg. Med. Chem. Lett.

      Volume: 25 Pages: 3307-3310

    • DOI

      10.1016/j.bmcl.2015.05.064

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-15H05838, KAKENHI-PUBLICLY-26102710, KAKENHI-PROJECT-15H04633, KAKENHI-PROJECT-25288073

  • [Journal Article] Synthesis of Peptide Nucleic Acids Containing a Crosslinking Agent and Evaluation of Their Reactivities2015
    • Author(s)
      T. Akisawa, Y. Ishizawa, F. Nagatsugi
    • Journal Title

      Molecules

      Volume: 20 Pages: 4708-4719

    • DOI

      10.3390/molecules20034708

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K14975, KAKENHI-PLANNED-15H05838, KAKENHI-PUBLICLY-26102710, KAKENHI-PROJECT-25288073

  • [Journal Article] A New Strategy for Site-Specific Alkylation of DNA using Oligonucleotides Containing an Abasic site and Alkylating Probes2015
    • Author(s)
      N. Sato, G. Tsuji, Y. Sasaki, A. Usami, T. Moki, K. Onizuka, K. Yamada and F. Nagatsugi
    • Journal Title

      Chem.Commun.

      Volume: 51 Pages: 14885-14888

    • DOI

      10.1039/c5cc03915k

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-15H05838, KAKENHI-PUBLICLY-26102710, KAKENHI-PROJECT-25288073

  • [Journal Article] Crosslinking Reactions of 4-Amino-6-oxo-2-vinylpyrimidine with Guanine Derivatives and Structural Analysis of the Adducts2015
    • Author(s)
      S.Kusano, S. Ishiyama,Sik Lok Lam, T. Mashima, M. Katahira, K. Miyamoto, M. Aida, F. Nagatsugi
    • Journal Title

      Nucleic Acids Res.

      Volume: 43 Pages: 7717-7730

    • DOI

      10.1093/nar/gkv797

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K14975, KAKENHI-PUBLICLY-15H00813, KAKENHI-PLANNED-15H05838, KAKENHI-PUBLICLY-26102710, KAKENHI-PUBLICLY-26102733, KAKENHI-PROJECT-26840020, KAKENHI-PROJECT-25288073, KAKENHI-PROJECT-25291013

  • [Journal Article] Automatic Pseudorotaxane Formation Targeting on Nucleic Acids Using a Pair of Reactive Oligodeoxynucleotides2014
    • Author(s)
      Kazumitsu Onizuka*, Fumi Nagatsugi, Yoshihiro Ito, Hiroshi Abe
    • Journal Title

      J. Am. Chem. Soc.

      Volume: 136 Pages: 7201-7204

    • DOI

      10.1021/ja5018283

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25282240, KAKENHI-PROJECT-25288073, KAKENHI-PUBLICLY-26102710, KAKENHI-PROJECT-26860007

  • [Journal Article] Development of Crosslinking Reactions to RNA Triggered by Oxidation2014
    • Author(s)
      Shuhei Kusano, Takuya Haruyama, Shogo Ishiyama, Shinya Hagihara, Fumi Nagatsugi
    • Journal Title

      Chem. Commun

      Volume: 50 Pages: 3951-3954

    • DOI

      10.1039/c3cc49463b

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-13J09123, KAKENHI-PROJECT-21229002, KAKENHI-PUBLICLY-24102508, KAKENHI-PROJECT-25288073, KAKENHI-PROJECT-25620122, KAKENHI-PUBLICLY-26102710

  • [Journal Article] Synthesis of Peptide-conjugated Light-driven Molecular Motors and Evaluation of Their DNA-binding Properties2013
    • Author(s)
      Fumi Nagatsugi, Yusuke Takahashi, Maiko Kobayashi, Shunsuke Kuwahara, Shuhei Kusano, Tomoko Chikuni, Shinya Hagihara and Nobuyuki Harada
    • Journal Title

      Mol. BioSyst.

      Volume: 9 Pages: 969-973

    • DOI

      10.1039/c2mb25520k

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-13J09123, KAKENHI-PROJECT-21229002, KAKENHI-PROJECT-22750159, KAKENHI-PROJECT-23659002, KAKENHI-PUBLICLY-24102508, KAKENHI-PROJECT-25288073

  • [Journal Article] The crosslink formation of 2'-OMe oligonucleotide containing 2-amino-6-vinyl- purine protects mRNA from miRNA- mediated silencing2013
    • Author(s)
      Shinya Hagihara, Wei-Chen Lin, Shuhei Kusano, Xiao-guang Chao, Tsuneaki Hori, Shuhei Imoto, Fumi Nagatsugi
    • Journal Title

      Chembiochem

      Volume: 14 Pages: 1427-1429

    • DOI

      10.1002/cbic.201300382

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-13J09123, KAKENHI-PROJECT-21229002, KAKENHI-PUBLICLY-24102508, KAKENHI-PUBLICLY-24115701, KAKENHI-PROJECT-25288073

  • [Journal Article] 4-vinyl-substituted pyrimidine nucleosides exhibit the efficient and selective formation of interstrand cross-links with RNA and duplex DNA.2013
    • Author(s)
      Nishimoto, A., Jitsuzaki, D., Onizuka, K., Taniguchi, Y., Nagatsugi, F. and Sasaki, S
    • Journal Title

      Nucleic Acids Research

      Volume: 41 Pages: 6774-6781

    • DOI

      10.1093/nar/gkt197

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229002, KAKENHI-PUBLICLY-24102508, KAKENHI-PROJECT-25288073

  • [Journal Article] Fast DNA Interstrand Cross-linking Reaction by6-Vinylpurine2012
    • Author(s)
      Imoto, S., Chikuni, T., Kansui, H, Kunieda, T. , Nagatsugi, F.
    • Journal Title

      Nucleosides, Nucleotides and Nucleic Acids

      Volume: 31 Pages: 752-762

    • DOI

      10.1080/15257770.2012.726756

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659002, KAKENHI-PROJECT-23790146, KAKENHI-PUBLICLY-24102508

  • [Journal Article] Production of truncated protein by the crosslink formation of mRNA with 2'-OMe oligoribonucleotide containing 2-amino-6-vinylpurine2012
    • Author(s)
      Hagihara, S., Kusano, S., Lin, W.C., Chao, X.G., Hori, T., Imoto, S., Nagatsugi, F.
    • Journal Title

      BIOORGANIC MEDICINAL CHEMISTRY LETTERS

      Volume: 22 Pages: 3870-3872

    • DOI

      10.1016/j.bmcl.2012.04.123

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659002, KAKENHI-PROJECT-23750180, KAKENHI-PROJECT-23790146, KAKENHI-PUBLICLY-24102508, KAKENHI-PUBLICLY-24115701

  • [Journal Article] Synthesis of6-amino-2-vinyl purine derivatives for cross-linking and evaluation of the reactivity2012
    • Author(s)
      Kusano,S., Sakuraba, T., Hagihara, S., Nagatsugi, F.
    • Journal Title

      Bioorganic & Medicinal Chemistry Letters

      Volume: 22 Pages: 6957-6951

    • DOI

      10.1016/j.bmcl.2012.08.122

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659002, KAKENHI-PROJECT-23750180, KAKENHI-PUBLICLY-24102508

  • [Journal Article] 自己活性化インテリジェント人工核酸の創製2011
    • Author(s)
      永次　史
    • Journal Title

      核酸化学のニュートレンド, DNA・RNAの新たな可能性を拓く, CSJ カレントレビュー（化学同人）

      Volume: 06 Pages: 48-55

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659002

  • [Journal Article] 自己活性化インテリジェント人工核酸の創製2011
    • Author(s)
      永次史
    • Journal Title

      核酸化学のニュートレンド,DNA・RNAの新たな可能性を拓く,CSJカレントレビュー

      Pages: 48-55

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659002

  • [Journal Article] Development of the Highly Selective Reactions to Target Gene for the Control of the Gene Expression in Cells2011
    • Author(s)
      F.Nagatsugi
    • Journal Title

      Journal of Synthetic Organic Chemistry Japan

      Volume: 69 Pages: 108-117

    • NAID

      10027916316

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659002

  • [Journal Article] Induced cross-linking reactions to target genes using modified oligonucleotides2011
    • Author(s)
      F. Nagatsugi, and S. Imoto
    • Journal Title

      Organic & Biomolecular Chemistry

      Volume: 9 Pages: 2579-2585

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21350086

  • [Journal Article] Development of the Highly Selective Reactions to Target Gene for the Control of the Gene Expression in Cells2011
    • Author(s)
      F. Nagatsugi
    • Journal Title

      Journal of Synthetic Organic Chemistry Japan

      Volume: 69 Pages: 108-117

    • NAID

      10027916316

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21350086

  • [Journal Article] 自己活性化インテリジェント人工核酸の創製2011
    • Author(s)
      永次史
    • Journal Title

      化学同人

      Pages: 48-55

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21350086

  • [Journal Article] チミンとの架橋反応性を有する新規人工核酸の開発2011
    • Author(s)
      永次史
    • Journal Title

      化学工業

      Volume: 62 Pages: 137-142

    • Data Source
      KAKENHI-PROJECT-21350086

  • [Journal Article] チミンとの架橋反応性を有する新規人工核酸の開発2011
    • Author(s)
      永次史
    • Journal Title

      化学工業

      Volume: 62 Pages: 137-142

    • Data Source
      KAKENHI-PROJECT-23659002

  • [Journal Article] Induced cross-linking reactions to target genes using modified oligonucleotides2011
    • Author(s)
      F.Nagatsugi,and S.
    • Journal Title

      Organic & Biomolecular Chemistry

      Volume: 9 Pages: 2579-2585

    • DOI

      10.1039/c0ob00819b

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659002, KAKENHI-PROJECT-23790146

  • [Journal Article] Synthesis of Reactive Oligonucleotides for Gene Targeting and Their Application to Gene Expression Regulation2010
    • Author(s)
      Nagatsugi, F.; Sasaki, S.
    • Journal Title

      Bulletin of the Chemical Society of Japan

      Volume: 83 Pages: 744-755

    • NAID

      10027174779

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21350086

  • [Journal Article] インテリジェント核酸を用いた細胞内遺伝子発現制御2010
    • Author(s)
      永次史、佐々木茂貴
    • Journal Title

      Antisense(アンチセンスDNA/RNA研究会)

      Volume: vol14, No1 Pages: 19-30

    • Data Source
      KAKENHI-PROJECT-21350086

  • [Journal Article] The alkyl-connected 2-amino-6-vinylpurine (AVP) crosslinking agent for improved selectivity to the cytosine base in RNA2010
    • Author(s)
      Taniguchi, Y.; Kurose, Y.; Nishioka, T.; Nagatsugi, F.; Sasaki, S.
    • Journal Title

      Bioorganic & Medicinal Chemistry

      Volume: 18 Pages: 2894-2901

    • NAID

      120005227462

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21350086

  • [Journal Article] Alteration of cross-linking selectivity with the 2'-OMe analogue of 2-amino-6-vinylpurine and evaluation of antisense effects2010
    • Author(s)
      S. Imoto, T. Hori, S. Hagihara, Y. Taniguchi, S. Sasaki, F. Nagatsugi
    • Journal Title

      Bioorg. Med. Chem. Lett

      Volume: 20 Pages: 6121-6124

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21350086

  • [Journal Article] Synthesis of Reactive Oligonucleotides for Gene Targeting and Their Application to Gene Expression Regulation2010
    • Author(s)
      F. Nagatsugi. and S. Sasaki
    • Journal Title

      Bull. Chem. Soc. Jpn

      Volume: 83 Pages: 744-755

    • NAID

      10027174779

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21350086

  • [Journal Article] Synthesis of Reactive Oligonucleotides foe Gene Targeting and Their Application to Gene Expression Regulation2010
    • Author(s)
      Nagatsugi F., et al
    • Journal Title

      Bull.Chem.Soc.Jpn

      Volume: 83 Pages: 744-755

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229002

  • [Journal Article] Alteration of cross-linking selectivity with the 2'-OMe analogue of 2-amino-6-vinylpurine and evaluation of antisense effects2010
    • Author(s)
      Imoto, S.; Hori, T.; Hagihara, S.; Taniguchi, Y.; Sasaki, S.; Nagatsugi, F
    • Journal Title

      Bioorganic & Medicinal Chemistry Letters

      Volume: 20 Pages: 6121-6124

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21350086

  • [Journal Article] Incorporation of an inducible nucleotide analog into DNA by DNA polymerases2009
    • Author(s)
      M. M. Ali, S. Imoto, Y. Li , S. Sasaki and F. Nagatsugi
    • Journal Title

      Bioorg. Med. Chem.

      Volume: 17 Pages: 2859-2863

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21350086

  • [Journal Article] Evaluation of the antisense effect of PEGylated oligodeoxynucleotides containing intelligent nucleoside analogues2009
    • Author(s)
      Y.Taniguchi, Y.Kurose, T, Nishioka, F.Nagatsugi, S.Sasaki
    • Journal Title

      Nucleic Acids Symp.Ser 53

      Pages: 167-168

    • Data Source
      KAKENHI-PROJECT-21350086

  • [Journal Article] Incorporation of an inducible nucleotide analog into DNA by DNA po lymerases2009
    • Author(s)
      Md. M. Ali b, S. Imoto, Y. Li S. Sasaki F. Nagatsugi
    • Journal Title

      Bioorg. Med. Chem 17(In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659001

  • [Journal Article] Highly Selective and Efficient Interstrand Cross-Linking Formation to Thymine Without Photo-Irradiation2009
    • Author(s)
      Hattori, K., Hirohama, T., Imoto, S., Kusano, S., Nagatsugi F.
    • Journal Title

      Chem. Comm

      Pages: 6463-6465

    • DOI

      10.1039/b915381k

    • Data Source
      KAKENHI-PROJECT-21229002

  • [Journal Article] Incorporation of an inducible nucleotide analog into DNA by DNA polymerases2009
    • Author(s)
      M.M.Ali, S.Imoto, Y.Li, S.Sasaki, F.Nagatsugi
    • Journal Title

      Bioorg.Med.Chem. 17

      Pages: 2859-2863

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21350086

  • [Journal Article] Formation of highly selective and efficient interstrand cross-linking to thymine without photo-irradiation2009
    • Author(s)
      K. Hattori, T. Hirohama, S. Imoto, S. Kusano, F. Nagatsugi
    • Journal Title

      Chem. Commun

      Volume: 42 Pages: 6463-6465

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21350086

  • [Journal Article] Design and Synthesis of the Novel cross-linking Agent2009
    • Author(s)
      S.Kusano, K.Hattori, S.Imoto, F.Nagatsugi
    • Journal Title

      Nucleic Acids Symp.Ser 53

      Pages: 169-170

    • Data Source
      KAKENHI-PROJECT-21350086

  • [Journal Article] Incorporation of an inducible nucleotide analog into DNA by DNA polymerases2009
    • Author(s)
      Md. M. Ali b, S. Imoto, Y. Li S. Sasaki F. Nagatsugi
    • Journal Title

      Bioorg. Med. Chem 17(In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19021004

  • [Journal Article] Formation of Highly Selective and Efficient Interstrand Cross-Linking to Thymine Without Photo-Irradiation2009
    • Author(s)
      Hattori, K. ; Hirohama, T. ; Imoto, S. ; Kusano, S. ; Nagatsugi, F.
    • Journal Title

      Chem.Comm. 42

      Pages: 6463-6465

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21350086

  • [Journal Article] Incorporation of an inducible nucleotide analog into DNA by DNA polymerases2009
    • Author(s)
      Md. M. Ali b, S. Imoto, Y. Li S. Sasaki F. Nagatsugi
    • Journal Title

      Bioorg. Med. Chem. 17(In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19350079

  • [Journal Article] Incorporation of inducible nucleotide analog into DNA by DNA polymerases2009
    • Author(s)
      Ali M. M., Imoto S., Li Y., Sasaki S. Nagatsugi F.
    • Journal Title

      Bioorg. Med. Chem. 17

      Pages: 2859-2863

    • Data Source
      KAKENHI-PROJECT-17209001

  • [Journal Article] Synthesis and Evaluation of the Luciferase-Oligodeoxynucleotide for the Sequences-Selective Detection of Nucleic Acids2008
    • Author(s)
      F. Nagatsugi, R. Nakahara, K. Inoue, S. Sasaki
    • Journal Title

      Arch. Pharm. Chem. Life Sei.,,(2008) 341

      Pages: 562-567

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19021004

  • [Journal Article] Synthesis and Evaluation of the Peptide Nucleic Acids (PNAs) Incorporating Reactive Artificial Molecules2008
    • Author(s)
      S. Imoto, M. Goto, T. Hirohama, F. Nagatsugi
    • Journal Title

      Collection symposium series (2008) 10

      Pages: 414-416

    • Data Source
      KAKENHI-PROJECT-19350079

  • [Journal Article] DNA Templated Click Chemistry for Creation of Novel DNA Binding Molecules2008
    • Author(s)
      Imoto S., Hirohama T., Nagatsugi F.
    • Journal Title

      Bioorg. Chem. Lett. 18

      Pages: 5660-5663

    • Data Source
      KAKENHI-PROJECT-17209001

  • [Journal Article] DNA Templated Click Chemistry for Creation of Novel DNA Binding Molecules2008
    • Author(s)
      Imoto S., Hirohama T., Nagatsugi F.
    • Journal Title

      Bioorg. Chem. Lett. 18

      Pages: 5660-5663

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19350079

  • [Journal Article] Synthesis and Evaluation of the Luciferase-Oligodeoxynucleotide for the Sequences-Selective Detection of Nucleic Acids2008
    • Author(s)
      F. Nagatsugi, R. Nakahara, K. Inoue, S. Sasaki
    • Journal Title

      Arch. Pharm. Chem. Life Sci., (2008) 341

      Pages: 562-567

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659001

  • [Journal Article] Synthesis of the Peptide Nucleic Acid (PNA) Incorporating 2-Amino-6-vinylpurine Derivative and Evaluation of the Reactivity2008
    • Author(s)
      S. Imoto, A. Shimotazawa, M. Goto, T. Hirohama, F. Nagatsugi
    • Journal Title

      Nucleic Acids Symp. Ser 52

      Pages: 391-392

    • Data Source
      KAKENHI-PROJECT-19021004

  • [Journal Article] Synthesis and Evaluation of the Luciferase-Oligodeoxynucleotide for the Sequences-Selective Detection of Nucleic Acids2008
    • Author(s)
      F. Nagatsugi, R. Nakahara, K. Inoue, S. Sasaki
    • Journal Title

      Arch. Pharm. Chem. Life Sci., (2008) 341

      Pages: 562-567

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19350079

  • [Journal Article] New Methodology to Search for DNA Binding Ligands Basedon Duplex DNA-Templated Click Chemistry2008
    • Author(s)
      S. Imoto, T. Hirohama, F. Nagatsugi
    • Journal Title

      Nucleic Acids Symp. Ser 52

      Pages: 381-382

    • Data Source
      KAKENHI-PROJECT-19021004

  • [Journal Article] New Methodology to Search for DNA Binding Ligands Basedon Duplex DNA-Templated Click Chemistry2008
    • Author(s)
      S. Imoto, T. Hirohama, F. Nagatsugi
    • Journal Title

      Nucleic Acids Symp. Ser. 52

      Pages: 381-382

    • Data Source
      KAKENHI-PROJECT-19350079

  • [Journal Article] Synthesis and Evaluation of the Luciferase-Oligodeoxynucleotide for the Sequences-Selective Detection of Nucleic Acids2008
    • Author(s)
      Nagatsugi F., Nakahara R., Inoue K., Sasaki S.
    • Journal Title

      Arch. Pharm. Chem. Life Sci. 341

      Pages: 562-567

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19350079

  • [Journal Article] Synthesis of the Peptide Nucleic Acid (PNA) Incorporating 2-Amino-6- vinylpurine Derivative and Evaluation of the Reactivity2008
    • Author(s)
      S. Imoto, A. Shimotazawa, M. Goto, T. Hirohama, F. Nagatsugi
    • Journal Title

      Nucleic Acids Symp. Ser 52

      Pages: 391-392

    • Data Source
      KAKENHI-PROJECT-19659001

  • [Journal Article] Synthesis and Evaluation of the Luciferase-Oligodeoxynucleotide for the Sequencse-Selective Detection of Nucleic Acids2008
    • Author(s)
      Nagatsugi F., Nakahara R., Inoue K., Sasaki S.
    • Journal Title

      Arch. Pharm. Chem. Life Sci. 341

      Pages: 562-567

    • Data Source
      KAKENHI-PROJECT-17209001

  • [Journal Article] New Methodology to Search for DNA Binding Ligands Based on Duplex DNA-Templated Click Chemistry2008
    • Author(s)
      Imoto S., Hirohama, T., Nagatsugi F.
    • Journal Title

      Nucleic Acids Symp. Ser. 52

      Pages: 381-382

    • Data Source
      KAKENHI-PROJECT-19350079

  • [Journal Article] Synthesis of the Peptide Nucleic Acid(PNA)Incorporating 2-Amino-6-vinylpurine Derivative and Evaluation of the Reactivity2008
    • Author(s)
      Imoto S., Shimotazawa A., Goto M., Hirohama T., Nagatsugi F.
    • Journal Title

      Nucleic Acids Symp. Ser. 52

      Pages: 391-392

    • Data Source
      KAKENHI-PROJECT-19350079

  • [Journal Article] Synthesis and Evaluation of the Peptide Nucleic Acids (PNAs) Incorpo rating Reactive Artificial Molecules2008
    • Author(s)
      S. Imoto, M.Goto, T. Hirohama, F. Nagatsugi
    • Journal Title

      Collection symposium series (2008) 10

      Pages: 414-416

    • Data Source
      KAKENHI-PROJECT-19659001

  • [Journal Article] Synthesis of the new nucleoside analogue connecting 2-amino-6-vinylpurine to the 2'-deoxyribose skeleton via the methylene linker2008
    • Author(s)
      Y. Kurose, Y. Taniguchi, F. Nagatsugi, S. Sasaki
    • Journal Title

      Nucleic Acids Symp. Ser. 52

      Pages: 43-44

    • Data Source
      KAKENHI-PROJECT-19350079

  • [Journal Article] DNA Templated Click Chemistry for Creation of Novel DNABinding Molecules2008
    • Author(s)
      S. Imoto, T. Hirohama, F. Nagatsugi
    • Journal Title

      Bioorg. Med. Chem. Lett 18

      Pages: 5660-5663

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659001

  • [Journal Article] Synthesis and Evaluation of the Luciferase-Oligodeoxynucleotide for the Sequence-Selective Detection of Nucleic Acids2008
    • Author(s)
      Nagatsugi F, Nakahara R., Inoue K., Sasaki S
    • Journal Title

      Arch. Pharm. Chem. Life Sci 341

      Pages: 562-567

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209001

  • [Journal Article] Synthesis of the Peptide Nucleic Acid (PNA) Incorporating 2-Amino-6-vinylpurine Derivative and Evaluation of the Reactivity2008
    • Author(s)
      S. Imoto, A. Shimotazawa, M. Goto, T. Hirohama, F. Nagatsugi
    • Journal Title

      Nucleic Acids Symp. Ser. 52

      Pages: 391-392

    • Data Source
      KAKENHI-PROJECT-19350079

  • [Journal Article] Synthesis and Evaluation of the Peptide Nucleic Acids (PNAs) Incorp orating Reactive Artificial Molecules2008
    • Author(s)
      S. Imoto, M.Goto, T. Hirohama , F. Nagatsugi
    • Journal Title

      Collection symposium series(2008) 10

      Pages: 414-416

    • Data Source
      KAKENHI-PROJECT-19021004

  • [Journal Article] DNA Templated Click Chemistry for Creation of Novel DNABinding Molecules2008
    • Author(s)
      S. Imoto, T. Hirohama, F. Nagatsugi
    • Journal Title

      Bioorg. Med. Chem. Lett 18

      Pages: 5660-5663

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19021004

  • [Journal Article] New Methodology to Search for DNA Binding Ligands Basedon Duplex DNA-Templated Click Chemistry2008
    • Author(s)
      S. Imoto, T. Hirohama, F. Nagatsugi
    • Journal Title

      Nucleic Acids Symp. Ser 52

      Pages: 381-382

    • Data Source
      KAKENHI-PROJECT-19659001

  • [Journal Article] Synthesis of the new nucleoside analogue connecting 2-amino-6-vinylpurine to the 2'-deoxyribose skeleton via the methylene linker2008
    • Author(s)
      Kurose Y., Taniguchi Y., Nagatsugi F., Sasaki S.
    • Journal Title

      Nucleic Acids Symp. Ser. 52

      Pages: 391-392

    • Data Source
      KAKENHI-PROJECT-19350079

  • [Journal Article] Synthesis of new nucleosides analogue connecting 2-amino-6-vinylpurine to the 2'-deoxyribose skeleton via the methylene linker.2008
    • Author(s)
      Kurose Y., Taniguchi, Y., Nagatsugi R, Sasaki S.
    • Journal Title

      Nucleic Acids Symp., Ser. 52

      Pages: 43-44

    • Data Source
      KAKENHI-PROJECT-17209001

  • [Journal Article] DNA Templated Click Chemistry for Creation of Novel DNA Binding Molecules2008
    • Author(s)
      S. Imoto, T. Hirohama, F. Nagatsugi
    • Journal Title

      Bioorg. Med. Chem. Lett. 18

      Pages: 5660-5663

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19350079

  • [Journal Article] Synthesis of the new nucleoside analogue connecting 2-amino-6-vinylpurine to the 2'-deoxyribose skeleton via the methylene linker2008
    • Author(s)
      Y. Kurose, Y. Taniguchi, F. Nagatsugi, S. Sasaki
    • Journal Title

      Nucleic Acids Symp. Ser 52

      Pages: 43-44

    • Data Source
      KAKENHI-PROJECT-19659001

  • [Journal Article] Development of the Novel Drug Releasing System Triggered by Hybridization with Target Sequence2007
    • Author(s)
      Nagatsugi, F.; Nakayama, S.; Sasaki, S.
    • Journal Title

      Nucleosides, Nucleotides Nucleic Acids 26

      Pages: 799-803

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19350079

  • [Journal Article] Development of the Novel Drug Releasing System Triggered by Hybridization with Target Sequence2007
    • Author(s)
      Nagatsugi, F.
    • Journal Title

      Nucleosides, Nucleotides Nucleic Acids 26

      Pages: 799-803

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659001

  • [Journal Article] Efficient Synthesis of 6-Substituted Purine Derivatives Using Pd-Catalyzed Cross-Coupling Reactions with 2'-Deoxyguanosine O^6-Tosylate2007
    • Author(s)
      Nagatsugi F.
    • Journal Title

      Heterocycles 73

      Pages: 493-501

    • NAID

      40015763816

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659001

  • [Journal Article] Efficient Synthesis of 6-Substituted Purine Derivatives Using Pd-Catalyzed Cross-Coupling Reactions with 2'-Deoxyguanosine O^6-Tosylate2007
    • Author(s)
      Nagatsugi F.
    • Journal Title

      Heterocycles 73

      Pages: 493-501

    • NAID

      40015763816

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18032057

  • [Journal Article] Development of the Novel Drug Releasing System Triggered by Hybridization with Target Sequence,2007
    • Author(s)
      Nagatsugi, F.
    • Journal Title

      Nucleosides, Nucleotides Nucleic Acids 26

      Pages: 799-803

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19350079

  • [Journal Article] Enzymatic Incorporation of 2-amino-6-Vinylpurine Derivative2007
    • Author(s)
      Imoto, S.; Ali, M. M.; Li, Y.; Sasaki, S.; Nagatsugi, F.
    • Journal Title

      Nucleic Acids Symp. Ser. 51

      Pages: 357-358

    • Data Source
      KAKENHI-PROJECT-19350079

  • [Journal Article] Development of the Novel Drug Releasing System Triggered by Hybridization with Target Sequence2007
    • Author(s)
      Nagatsugi, F.
    • Journal Title

      Nucleosides, Nucleotides Nucleic Acids 26

      Pages: 799-803

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19021004

  • [Journal Article] Efficient Synthesis of 6-Substituted Purine Derivatives Using Pd-Catalyzed Cross-Coupling Reactions with 2'-Deoxyguanosine Ο^6-Tosylate2007
    • Author(s)
      Nagatsugi F.
    • Journal Title

      Heterocycles 73

      Pages: 493-501

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19350079

  • [Journal Article] Development of the Novel Drug Releasing System Triggered by Hybridization with Target Sequence,2007
    • Author(s)
      Nagatsugi, F.
    • Journal Title

      Nucleosides, Nucleotides Nucleic Acids 26

      Pages: 799-803

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18032057

  • [Journal Article] Efficient Synthesis of 6-Substituted Purine Derivatives Using Pd-Catalyzed Cross-Coupling Reactions with 2'-Deoxyguanosine O^6-Tosylate2007
    • Author(s)
      Nagatsugi F.; Ogata, Y ; Imoto, S.; Sasaki, S.
    • Journal Title

      Heterocycles 73

      Pages: 493-501

    • NAID

      40015763816

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19350079

  • [Journal Article] Efficient Synthesis of 6-Substituted Purine Derivatives Using Pd-Catalyzed Cross-Coupling Reactions with 2'-Deoxyguanosine O^6-Tosylate2007
    • Author(s)
      Nagatsugi F.
    • Journal Title

      Heterocycles 73

      Pages: 493-501

    • NAID

      40015763816

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19021004

  • [Journal Article] Intracellular Ability of an Inducible Alkylation System to Exhibit Antisense Effects with Greater Potency and Selectivity2006
    • Author(s)
      Ali M.M., Oishi M., Nagatsugi F., Mori K., Nagasaki Y., Kataoka K., Sasaki S
    • Journal Title

      Angew.Chem.Int.Ed (In press)

    • Data Source
      KAKENHI-PROJECT-17035063

  • [Journal Article] Intracelullar Ability of an Inducible Alkylation System to Exhibit Antisense Effects with Greater Potency and Selectivity2006
    • Author(s)
      Ali M.M., Oishi M., Nagatsugi F., Mori K., Nagasaki Y., Kataoka K., Sasaki S
    • Journal Title

      Angew.Chem.Int.Ed (In press)

    • Data Source
      KAKENHI-PROJECT-17209001

  • [Journal Article] Novel drug releasing system triggered by hybridization with target sequence,2006
    • Author(s)
      Nakayama S., Nagatsugi F., Sasaki S.
    • Journal Title

      Nucleic Acids Symp. Ser 50

      Pages: 143-144

    • Data Source
      KAKENHI-PROJECT-17209001

  • [Journal Article] Intracellular Ability of an Inducible Alkylation System to Exhibit Antisense Effects with Greater Potency and Selectivity2006
    • Author(s)
      Ali M.M., Oishi M., Nagatsugi F., Mori K., Nagasaki Y., Kataoka K., Sasaki S
    • Journal Title

      Angew.Chem.Int.Ed (In press)

    • Data Source
      KAKENHI-PROJECT-17550158

  • [Journal Article] Application of 2-Amino-6-Vinylpurine as an Efficient Agent for Conjugation of Oligonucleotides2006
    • Author(s)
      Ali M.M., Nagatsugi F., Sasaki S., Nakahara R., Maeda M
    • Journal Title

      Nucleosides, Nucleotides, and Nucleic Acids 25

      Pages: 159-169

    • Data Source
      KAKENHI-PROJECT-17550158

  • [Journal Article] Effects of Halogenated WNA Derivatives on Sequence Dependency for Expansion of Recognition Sequences in the Non-Natural Type Triplexes2006
    • Author(s)
      Taniguchi Y., Nakamura A., Senko Y., Nagatsugi F., Sasaki S
    • Journal Title

      J.Org.Chem (In press)

    • Data Source
      KAKENHI-PROJECT-17550158

  • [Journal Article] Application of 2-Amino-6-Vinylpurine as an Efficient Agent for Conjugation of Oligonucleotides2006
    • Author(s)
      Ali M.M., Nagatsugi F., Sasaki S., Nakahara R., Maeda M
    • Journal Title

      Nucleosides, Nucleotides, and Nucleic Acids 25

      Pages: 159-169

    • Data Source
      KAKENHI-PROJECT-17035063

  • [Journal Article] Application of 2-Amino-6-Vinylpurine as an Efficient Agent for Conjugation of Oligonucleotides2006
    • Author(s)
      Ali M.M., Nagatsugi F., Sasaki S., Nakahara R., Maeda M
    • Journal Title

      Nucleosides, Nucleotides, and Nucleic Acids 25

      Pages: 159-169

    • Data Source
      KAKENHI-PROJECT-17209001

  • [Journal Article] Effects of Halogenated WNA Derivatives on Sequence Dependency for Expansion of Recognition Sequences in the Non-Natural Type Triplexes2006
    • Author(s)
      Taniguchi Y., Nakamura A., Senko Y., Nagatsugi F., Sasaki S
    • Journal Title

      J.Org.Chem. (In press)

    • Data Source
      KAKENHI-PROJECT-17035063

  • [Journal Article] Substituent Effects on the In situ Activation of the Double Activated Cross-linking Reaction2005
    • Author(s)
      F.Nagatsugi, S.Mori, Md.Monsur Ali, Y.Ogata, S.Sasaki
    • Journal Title

      Nucleic Acids Symp.Ser 49

      Pages: 175-176

    • Data Source
      KAKENHI-PROJECT-17209001

  • [Journal Article] Smart Polyion Complex Micelled for Targeted IntracellularDelivery of PEGylated Antisense Oligonucleotide with Acid-Labile Linkag2005
    • Author(s)
      M.Oishi, F.Nagatsugi, S.Sasaki, Y.Nagasaki, K.Kataoka
    • Journal Title

      Chem Bio Chem (in press)(印刷中)

    • Data Source
      KAKENHI-PROJECT-15550148

  • [Journal Article] Supramolecular assemblies for the cytoplasmic delivery of antisense oligodeoxynucleotide : Polylon complex (PIC) micells based on poly(ethylene glycol)-SS-oligodeoxynucleotide conjugate2005
    • Author(s)
      M.Oishi, T.Hayama, Y.Akiyama, S.Takae, A.Harada, Y.Yamasaki, F.Nagatsugi, S.Sasaki, Y.Nagasaki, K.Kataoka
    • Journal Title

      Biomacromolecules 6

      Pages: 2449-2454

    • Data Source
      KAKENHI-PROJECT-17035063

  • [Journal Article] Hybridization-Promoted and Cytidine-Selective Activation for Cross-Linking with the Use of 2-Amino-6-Vinylpurine Derivatives2005
    • Author(s)
      T.Kawasaki, F.Nagatsugi, Md.Monsur Ali, M.Maeda, K.Sugiyama, K.Hori, S.Sasaki
    • Journal Title

      J.Org.Chem. 70

      Pages: 14-23

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15550148

  • [Journal Article] Supramolecular assemblies for the cytoplasmic delivery of antisense oligodeoxynucleotide: Polylon complex (PIC) micelles based on poly(ethylene glycol)-SS-oligodeoxynucleotide conjugate2005
    • Author(s)
      M.Oishi, T.Hayama, Y.Akiyama, S.Takae, A.Harada, T.Yarnasaki, F.Nagatsugi, S.Sasaki, Y.Nagasaki, K.Kataoka
    • Journal Title

      Biomacromolecules 6

      Pages: 2449-2454

    • Data Source
      KAKENHI-PROJECT-17209001

  • [Journal Article] Substituent Effects on the In situ Activation of the Double Activated Cross-linking Reaction2005
    • Author(s)
      F.Nagatsugi, S.Mori, Md.Monsur Ali, Y.Ogata, S.Sasaki
    • Journal Title

      Nucleic Acids Symp.Ser 49

      Pages: 175-176

    • Data Source
      KAKENHI-PROJECT-17035063

  • [Journal Article] Design of highly efficient and selective transfer reaction of nitrosyl group to dC and d^mC resulting in specific deamination2005
    • Author(s)
      Md.Monsur Ali, Nagatsugi F., Nakayama S., Md.Rowshon Alam, Kawasaki T., Sasaki S
    • Journal Title

      Nucleosides Nucleotides Nucleic Acid 24

      Pages: 721-724

    • Data Source
      KAKENHI-PROJECT-17035063

  • [Journal Article] Supramolecular assemblies for the cytoplasmic delivery of antisense oligodeoxynucleotide : Polylon complex (PIC) micelles based on poly(ethylene glycol)-SS-oligodeoxynucleotide conjugate2005
    • Author(s)
      M.Oishi, T.Hayama, Y.Akiyama, S.Takae, A.Harada, Y.Yamasaki, F.Nagatsugi, S.Sasaki, Y.Nagasaki, K.Kataoka
    • Journal Title

      Biomacromolecules 6

      Pages: 2449-2454

    • Data Source
      KAKENHI-PROJECT-17550158

  • [Journal Article] Smart Polyion Complex Micelles for Targeted Intracellular Delivery of PEGylated Antisense Oligonucleotide with Acid-Labile Linkage2005
    • Author(s)
      Oishi, M., F.Nagatsugi, Sasaki, S, Nagasaki, Y., Kataoka, K
    • Journal Title

      ChemBioChem 6

      Pages: 718-725

    • Data Source
      KAKENHI-PROJECT-17209001

  • [Journal Article] Smart Polyion Complex Micelles for Targeted Intracellular Delivery of PEGylated Antisense Oligonucleotide with Acid-Labile Linkage,2005
    • Author(s)
      Oishi, M., F.Nagatsugi, Sasaki, S., Nagasaki, Y., Kataoka, K
    • Journal Title

      ChemBioChem 6

      Pages: 718-725

    • Data Source
      KAKENHI-PROJECT-17550158

  • [Journal Article] Development of efficient packaging method of oligodeoxynucleotides by a condensed nano particle in lipid envelope structur2005
    • Author(s)
      Y.Yamada, K.Kogure, Y.Nakamura, K.Inoue, H.Akita, F.Nagatsugi, S.Sasaki, T.Suhara, H.Harashima
    • Journal Title

      Biol.Pharm.Bull 28

      Pages: 1939-1942

    • NAID

      110003666368

    • Data Source
      KAKENHI-PROJECT-17209001

  • [Journal Article] Hybridization-Promoted and Cytidine-Selective Activation for Cross-Linking with the Use of 2-Amino-6-Vinylpurine Derivatives2005
    • Author(s)
      Kawasaki, T., Nagatsugi, F., Md.Monsur Ali, Maeda, M., Sugiyama, K., Hori, K., Sasaki S
    • Journal Title

      J.Org.Chem. 70

      Pages: 14-23

    • Data Source
      KAKENHI-PROJECT-17035063

  • [Journal Article] Substituent Effects on the In situ Activation of the Double Activated Cross-linking Reaction2005
    • Author(s)
      F.Nagatsugi
    • Journal Title

      Nucleic Acids Symp. Ser 49

      Pages: 175-176

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17550158

  • [Journal Article] Expansion of triplex recognition codes by the use of novel bicyclic nucleoside derivatives (WNA)2005
    • Author(s)
      Taniguchi, Y., Nakamura, A., Senko, Y., Kodama, K., Nagatsugi, F., Sasaki, S
    • Journal Title

      Nucleosides Nucleotides Nucleic Acid 24

      Pages: 823-827

    • Data Source
      KAKENHI-PROJECT-17035063

  • [Journal Article] Development of efficient packaging method of oligodeoxynucleotides by a condensed nano particle in lipid envelope structur2005
    • Author(s)
      Y.Yamada, K.Kogure, Y.Nakamura, K.Inoue, H.Akita, F.Nagatsugi, S.Sasaki, T.Suhara, H.Harashima
    • Journal Title

      Biol.Pharm.Bull 28

      Pages: 1939-1942

    • NAID

      110003666368

    • Data Source
      KAKENHI-PROJECT-17550158

  • [Journal Article] Design of highly efficient and selective transfer reaction of nitrosyl group to dC and d^mC resulting in specific deamination,2005
    • Author(s)
      Md.Monsur Ali, Nagatsugi, F., Nakayama, S., Md.Rowshon Alam, Kawasaki, T., Sasaki, S
    • Journal Title

      Nucleosides Nucleotides Nucleic Acid 24

      Pages: 721-724

    • Data Source
      KAKENHI-PROJECT-17550158

  • [Journal Article] Substituent Effects on the In situ Activation of the Double Activated Cross-linking Reaction2005
    • Author(s)
      F.Nagatsugi, _S.Mori, Md.Monsur Ali, Y.Ogata, S.Sasaki
    • Journal Title

      Nucleic Acids Symp.Ser 49

      Pages: 175-176

    • Data Source
      KAKENHI-PROJECT-17550158

  • [Journal Article] Smart Polyion Complex Micells for Targeted Intracellular Delivery of PEGylated Antisense Oligonucleotide with Acid-Labile Linkage2005
    • Author(s)
      Oishi, M., F.Nagatsugi, Sasaki, S., Nagasaki, Y., Kataoka, K
    • Journal Title

      ChemBioChem 6

      Pages: 718-725

    • Data Source
      KAKENHI-PROJECT-17035063

  • [Journal Article] Hybridization-Promoted and Cytidine-Selective Activation for Cross-Linking with the Use of 2-Amino-6-Vinylpurine Derivatives2005
    • Author(s)
      Kawasaki, T., Nagatsugi, F.Md.Monsur Ali, Maeda, M., Sugiyama, K., Hori, K., Sasaki, S
    • Journal Title

      J.Org.Chem 70

      Pages: 14-23

    • Data Source
      KAKENHI-PROJECT-17209001

  • [Journal Article] Hybridization-Promoted and Cytidine-Selective Activation for Cross-Linking with the Use of 2-Amino-6-Vinylpurine Derivatives2005
    • Author(s)
      Kawasaki, T., Nagatsugi, F., Md.Monsur Ali, Maeda, M., Sugiyama, K..Hori, K., Sasaki, S
    • Journal Title

      J.Org.Chem 70

      Pages: 14-23

    • Data Source
      KAKENHI-PROJECT-17550158

  • [Journal Article] Smart Polyion Complex Micelles for Targeted Intracellular Delivery of PEGylated Antisense Oligonucleotide with Acid-Labile Linkage2005
    • Author(s)
      M.Oishi, F.Nagatsugi, S.Sasaki, Y.Nagasaki, K.Kataoka
    • Journal Title

      Chem Bio Chem 6

      Pages: 718-725

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15550148

  • [Journal Article] Development of efficient packaging method of oligodeoxynucleotides by a condensed nano particle in lipid envelope structure2005
    • Author(s)
      Y.Yamada, K.Kogure, Y.Nakamura, K.Inoue, H.Akita, F.Nagatsugi, S.Sasaki, T.Suhara, H.Harashima
    • Journal Title

      Biol.Pharm.Bull 28

      Pages: 1939-1942

    • NAID

      110003666368

    • Data Source
      KAKENHI-PROJECT-17035063

  • [Journal Article] Expansion of triplex recognition codes by the use of novel bicyclic nucleoside derivatives (WNA)2005
    • Author(s)
      Taniguchi, T.; Nakamura, A.; Senko, Y.; Kodama, K.; Nagatsugi, F.; Sasaki, S.
    • Journal Title

      Nucleosides Nucleotides Nucleic Acids 24

      Pages: 823-827

    • Data Source
      KAKENHI-PROJECT-17209001

  • [Journal Article] Hybridization-Promoted and Cytidine-Selective Activation for Cross-Linking with the Use of 2-Amino-6-Vinylpurine Derivatives2005
    • Author(s)
      T.Kawasaki, F.Nagatsugi, Md.M.Ali, M.Maeda, K.Sugiyama, K.Hori, S.Sasaki
    • Journal Title

      J.Org.Chem. 70(1)

      Pages: 14-23

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15550148

  • [Journal Article] Smart Polyion Complex Micelles for Targeted IntracellularDelivery of PEGylated Antisense Oligonucleotide with Acid-Labile Linkag2005
    • Author(s)
      M.Oishi, F.Nagatsugi, S.Sasaki, Y.Nagasaki, K.Kataoka
    • Journal Title

      Chem Bio Chem 6

      Pages: 718-725

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15550148

  • [Journal Article] Expansion of triplex recognition codes by the use of novel bicyclic nucleoside derivatives (WNA)2005
    • Author(s)
      Taniguchi, Y., Nakamura, A., Senko, Y., Kodama, K., Nagatsugi, F., Sasaki, S
    • Journal Title

      Nucleosides Nucleotides Nucleic Acids 24

      Pages: 823-827

    • Data Source
      KAKENHI-PROJECT-17550158

  • [Journal Article] Efficient Antisense Effect Using the Functional Oligonucleotides Containing Cross-linking Agents Conjugated PEG,2004
    • Author(s)
      Ali Md.Monsur, F.Nagatsugi, M.Ohishi, Y.Nagasaki, K.Kataoka, S.Sasak
    • Journal Title

      Nucleic Acids Res.Symp.Ser. 48

      Pages: 61-62

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15550148

  • [Journal Article] Selective Nitrosyl Group Transfer Reaction to Cytidine Using Oligonucleotides Bearing S-Nitrosothioguanosine2004
    • Author(s)
      F.Nagatsugi, S.Nakayama, Ali Md.Monsur, S.Sasaki
    • Journal Title

      Nucleic Acids Res.Symp.Ser. 48

      Pages: 23-24

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15550148

  • [Journal Article] Chemical Tools for Targeted Mutagenesis of DNA Based on Triple Helix Formation2004
    • Author(s)
      F.Nagatsugi, S.Sasaki
    • Journal Title

      Biol.Pharm.Bull. 27

      Pages: 463-467

    • NAID

      110003608787

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15550148

  • [Journal Article] Selective Formation of Stable Triplexes Including a TA or a CG Interrupting Site with New Bicyclic Nucleoside Analogs (WNA)2004
    • Author(s)
      S.Sasaki, Y.Taniguchi, Y.Senko, K.Kodama, F.Nagatsugi, M.Maeda
    • Journal Title

      J.Am.Chem.Soc. 126

      Pages: 516-528

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15550148

  • [Journal Article] Sequence-and Base-Specific Delivery of Nitric Oxide to Cytidine and 5-Methylcytidine Leading to Efficient Deamination2004
    • Author(s)
      Md.M.Ali, Md.R.Alam, T.Kawasaki, F.Nagatsugi, S.Sasaki
    • Journal Title

      J.Am.Chem.Soc. 126

      Pages: 8864-8865

    • Data Source
      KAKENHI-PROJECT-15550148

  • [Journal Article] Selective Nitrosyl Group Transfer Reaction to Cytidine Using Oligonucleotides Bearing S-Nitrosothioguanosine2004
    • Author(s)
      F.Nagatsugi, S.Nakayama, Ali Md.Monsur., S.Sasaki
    • Journal Title

      Nucleic Acids Res.Suppl. 48

      Pages: 23-24

    • Data Source
      KAKENHI-PROJECT-15550148

  • [Journal Article] Efficient Antisense Effect Using the Functional Oligonucleotides Containing Cross-linking Agents Conjugated PEG2004
    • Author(s)
      Ali Md.Monsur, F.Nagatsugi, M.Ohishi, Y.Nagasaki, K.Kataoka, S.Sasaki
    • Journal Title

      Nucleic Acids Res.Symp.Ser. 48

      Pages: 61-62

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15550148

  • [Journal Article] Sequence- and Base-Specific Delivery of Nitric Oxide to Cytidine and 5-Methylcytidine Leading to Efficient Deamination2004
    • Author(s)
      Md.M.Ali, Md.R.Alam, T.Kawasaki, F.Nagatsugi, S.Sasaki
    • Journal Title

      J.Am.Chem.Soc. 126

      Pages: 8864-8865

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15550148

  • [Journal Article] Chemical Tools for Targeted Mutagenesis of DNA Based on Triple Helix Formation.2004
    • Author(s)
      F.Nagatsugi, S.Sasaki
    • Journal Title

      Biol.Pharm.Bull. 27

      Pages: 463-467

    • NAID

      110003608787

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15550148

  • [Journal Article] Efficient Antisense Effect Using the Functional Oligonucleotides Containing Cross-linking Agents Conjugated PEG2004
    • Author(s)
      Ali Md.Monsur, F.Nagatsugi, M.Ohishi, Y.Nagasaki, K.Kataoka, S.Sasak
    • Journal Title

      Nucleic Acids Res.Suppl. 48

      Pages: 61-62

    • Data Source
      KAKENHI-PROJECT-15550148

  • [Journal Article] Chemical Tools for Targeted Mutagenesis of DNA Based on Triple Helix Formation2004
    • Author(s)
      F.Nagatsugi, S.Sasaki
    • Journal Title

      Biol.Pharm.Bull.

      Pages: 463-467

    • NAID

      110003608787

    • Data Source
      KAKENHI-PROJECT-15550148

  • [Journal Article] Efficient cross-linking reactions by functional nucleobases capable of in situ activation under neutral conditions2003
    • Author(s)
      F.Nagatsugi, Y.Suenaga, S.Sasaki
    • Journal Title

      Nucleic Acids Res. Suppl., 3

      Pages: 155-156

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15550148

  • [Journal Article] Enhancement and inhibition by 2'-O-hydroxyethyl residues of gene targeting mediated by triple helix forming oligonucelotides2003
    • Author(s)
      Kundu M, Nagatsugi F, Majumdar A, Miller PS, Seidman MM.
    • Journal Title

      Nucleosides Nucleotides Nucleic Acids. 22(10)

      Pages: 1927-1938

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15550148

  • [Journal Article] Efficient cross-linking reactions by functional nucleobases capable of in situ activation under neutral conditions2003
    • Author(s)
      F.Nagatsugi, Y.Suenaga, S.Sasaki
    • Journal Title

      Nucleic Acids Res.Suppl. 3

      Pages: 155-156

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15550148

  • [Journal Article] Site-Specific Mutagenesis by Triple-Helix Forming Oligonucleotides Containing a Reactive Nucleoside Analogue2003
    • Author(s)
      Fumi Nagatsugi et al.
    • Journal Title

      Nucleic Acids Res. 31

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15550148

  • [Journal Article] Enhancement and inhibition by 2'-O-hydroxyethyl residues of gene targeting mediated by triple helix forming oligonucleotides2003
    • Author(s)
      Kundu M, Nagatsugi F et al.
    • Journal Title

      Nucleosides Nucleotides NucleicAcids. 22(10)

      Pages: 1927-1938

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15550148

  • [Journal Article] Site-Specific Mutagenesis by Triple-Helix Forming Oligonucleotides Containing a Reactive Nucleoside Analogue2003
    • Author(s)
      F.Nagatsugi, S.Sasaki, P.S.Miller, M.M.Seidman
    • Journal Title

      Nucleic Acids Res. 31

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15550148

  • [Journal Article] Production of truncated protein by the crosslink formation of mRNA with 2'-OMe oligoribonucleotide containing 2-amino-6-vinylpurine
    • Author(s)
      Hagihara, S., Kusano, S., Lin, W. C., Chao, X. G., Hori, T., Imoto, S., Nagatsugi, F.
    • Journal Title

      Bioorg. Med. Chem. Lett.

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21350086

  • [Patent] RNAの高次構造解析方法2021
    • Inventor(s)
      小松 リチャード 馨, 宮下 映見, 鬼塚 和 光, 永次 史
    • Industrial Property Rights Holder
      小松 リチャード 馨, 宮下 映見, 鬼塚 和 光, 永次 史
    • Industrial Property Rights Type
      特許
    • Filing Date
      2021
    • Data Source
      KAKENHI-PROJECT-20H02855

  • [Patent] RNAの高次構造解析方法2021
    • Inventor(s)
      小松 リチャード 馨, 宮下 映見, 鬼塚 和光, 永次　史
    • Industrial Property Rights Holder
      小松 リチャード 馨, 宮下 映見, 鬼塚 和光, 永次　史
    • Industrial Property Rights Type
      特許
    • Filing Date
      2021
    • Data Source
      KAKENHI-PROJECT-21K19038

  • [Presentation] Development of novel OFF-ON type alkylating reagents2022
    • Author(s)
      Yutong Chen, Kazumitsu Onizuka, Pingyun Lan, Fumi Nagatsugi
    • Organizer
      日本化学会 第102春季年会
    • Data Source
      KAKENHI-PROJECT-20H02855

  • [Presentation] Selective photo-labeling of G4 DNA-binding protein2022
    • Author(s)
      AHMED MOSTAFA ABDELHADY, Kazumitsu Onizuka, Tatsuki Masuzawa, Shinichi Sato, Takanori Oyoshi, Fumi Nagatsugi
    • Organizer
      日本化学会 第102春季年会
    • Data Source
      KAKENHI-PROJECT-20H02855

  • [Presentation] Selective photo-labeling of G4 DNA-binding protein2022
    • Author(s)
      AHMED MOSTAFA ABDELHADY, Kazumitsu Onizuka, Tatsuki Masuzawa, Shinichi Sato, Takanori Oyoshi, Fumi Nagatsugi
    • Organizer
      日本化学会 第102春季年会
    • Data Source
      KAKENHI-PROJECT-21K19038

  • [Presentation] RNA-蛍光指示薬間相互作用大規模解析情報を用いた疾患関連pre-miRNA結合分子の探索2022
    • Author(s)
      長澤 瞭佑、鬼塚 和光、小松 馨、宮下 映見、小澤 眞美子、齊藤 博英、永次 史
    • Organizer
      日本薬学会 第142年会
    • Data Source
      KAKENHI-PROJECT-20H02855

  • [Presentation] Nucleic Acids Chemistry beyond the Watson-Crick Double Helix (76) : Structure-based Chemical Modification of Berberine to Improve the RNA Binding Property2022
    • Author(s)
      Sagar Satpathi, Tamaki Endoh, Yutong Chen, Saki Matsumoto, Tatsuya Ohyama, Peter Podbev, Janez Plavec, Kazumitsu Onizuka, Fumi Nagatsugi, Naoki Sugimoto
    • Organizer
      日本化学会 第102春季年会
    • Data Source
      KAKENHI-PROJECT-21K19038

  • [Presentation] CGGリピートRNAの構造変換を誘起する1,3-diazaphenoxazine誘導体の開発2022
    • Author(s)
      村瀬 裕貴、永次 史、佐々木 茂貴
    • Organizer
      日本薬学会 第142年会
    • Data Source
      KAKENHI-PROJECT-20H02855

  • [Presentation] Nucleic Acids Chemistry beyond the Watson-Crick Double Helix (76) : Structure-based Chemical Modification of Berberine to Improve the RNA Binding Property2022
    • Author(s)
      Sagar Satpathi, Tamaki Endoh, Yutong Chen, Saki Matsumoto, Tatsuya Ohyama, Peter Podbev, Janez Plavec, Kazumitsu Onizuka, Fumi Nagatsugi, Naoki Sugimoto
    • Organizer
      日本化学会 第102春季年会
    • Data Source
      KAKENHI-PROJECT-20H02855

  • [Presentation] Synthesis and cross-link properties of 2-amino-6-vinyl-7-deazapurine-deoxyriboside for anti-miRNA therapy2022
    • Author(s)
      Nadya Syahla Soemawisastra, Hidenori Okamura, Fumi Nagatsugi
    • Organizer
      日本化学会 第102春季年会
    • Data Source
      KAKENHI-PROJECT-20H02855

  • [Presentation] 光感受性オキシム構造を用いた生体適合性の光誘起型環化反応の開発2022
    • Author(s)
      岡村 秀紀、飯田 百香、金山 唯、永次 史
    • Organizer
      日本化学会 第102春季年会
    • Data Source
      KAKENHI-PROJECT-21K19038

  • [Presentation] DACN-MMCと3-アジドクマリンを用いた生体分子の蛍光標識化2022
    • Author(s)
      林原 智也、河崎 悠也、鬼塚 和光、井川 和宣、永次 史、友岡 克彦
    • Organizer
      日本化学会 第102春季年会
    • Data Source
      KAKENHI-PROJECT-21K19038

  • [Presentation] CGGリピートRNAの構造変換を誘起する1,3-diazaphenoxazine誘導体の開発2022
    • Author(s)
      村瀬 裕貴、永次 史、佐々木 茂貴
    • Organizer
      日本薬学会 第142年会
    • Data Source
      KAKENHI-PROJECT-21K19038

  • [Presentation] 光感受性オキシム構造を用いた生体適合性の光誘起型環化反応の開発2022
    • Author(s)
      岡村 秀紀、飯田 百香、金山 唯、永次 史
    • Organizer
      日本化学会 第102春季年会
    • Data Source
      KAKENHI-PROJECT-20H02855

  • [Presentation] RNA結合大規模情報に基づいた新規蛍光指示薬の創製2022
    • Author(s)
      岩田 遼平、鬼塚 和光、長澤 瞭佑、村瀬 裕貴、永次 史
    • Organizer
      日本化学会 第102春季年会
    • Data Source
      KAKENHI-PROJECT-20H02855

  • [Presentation] Development of novel OFF-ON type alkylating reagents2022
    • Author(s)
      Yutong Chen, Kazumitsu Onizuka, Pingyun Lan, Fumi Nagatsugi
    • Organizer
      日本化学会 第102春季年会
    • Data Source
      KAKENHI-PROJECT-21K19038

  • [Presentation] RNA結合大規模情報に基づいた新規蛍光指示薬の創製2022
    • Author(s)
      岩田 遼平、鬼塚 和光、長澤 瞭佑、村瀬 裕貴、永次 史
    • Organizer
      日本化学会 第102春季年会
    • Data Source
      KAKENHI-PROJECT-21K19038

  • [Presentation] RNA-蛍光指示薬間相互作用大規模解析情報を用いた疾患関連pre-miRNA結合分子の探索2022
    • Author(s)
      長澤 瞭佑、鬼塚 和光、小松 馨、宮下 映見、小澤 眞美子、齊藤 博英、永次 史
    • Organizer
      日本薬学会 第142年会
    • Data Source
      KAKENHI-PROJECT-21K19038

  • [Presentation] Synthesis and cross-link properties of 2-amino-6-vinyl-7-deazapurine-deoxyriboside for anti-miRNA therapy2022
    • Author(s)
      Nadya Syahla Soemawisastra, Hidenori Okamura, Fumi Nagatsugi
    • Organizer
      日本化学会 第102春季年会
    • Data Source
      KAKENHI-PROJECT-21K19038

  • [Presentation] DACN-MMCと3-アジドクマリンを用いた生体分子の蛍光標識化2022
    • Author(s)
      林原 智也、河崎 悠也、鬼塚 和光、井川 和宣、永次 史、友岡 克彦
    • Organizer
      日本化学会 第102春季年会
    • Data Source
      KAKENHI-PROJECT-20H02855

  • [Presentation] Unnatural base pairs with spatially isolated pseudo-nucleobases in the m+A25:D40ajor groove of DNA2021
    • Author(s)
      Hidenori Okamura, Zhuoxin Dong, Giang Hoang Trinh, Yoshiaki Masaki, Kohji Seio, Fumi Nagatsugi
    • Organizer
      Pacifichem2021 Satellite Symposium - Modified DNA and XNA for therapeutic application
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K19038

  • [Presentation] RNA結合性・アルキル化反応性の大規模解析技術開発2021
    • Author(s)
      鬼塚和光、小松リチャード馨、長澤瞭佑、Yutong Chen、宮下映見、石川竣也、小嶋かんな、村瀬裕貴、小澤眞美子、齊藤博英、永次史
    • Organizer
      第15回 バイオ関連化学シンポジウム
    • Data Source
      KAKENHI-PROJECT-20H02855

  • [Presentation] RNA標的低分子創薬を目指したRNA－蛍光指示薬間相互作用大規模解析2021
    • Author(s)
      長澤瞭佑、鬼塚和光、小松リチャード馨、宮下映見、小澤眞美子、齊藤博英、永次史
    • Organizer
      第11回CSJ化学フェスタ2021
    • Data Source
      KAKENHI-PROJECT-21K19038

  • [Presentation] Development of 2-amino-6-vinyl-7-deazapurine-deoxyriboside as an efficient cross-linking nucleoside for anti-miRNA therapy2021
    • Author(s)
      Nadia Syahla Soemawisastra, Hidenori Okamura, Fumi Nagatsugi
    • Organizer
      IS3NA-IRT Virtual Symposium 2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H02855

  • [Presentation] RNA-小分子間化学シグナル大規模解析技術の展開2021
    • Author(s)
      鬼塚和光、小松リチャード馨、齊藤博英、永次史
    • Organizer
      「化学コミュニケーションのフロンティア」第8回公開シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K19038

  • [Presentation] Development of the reactive OFF-ON type alkylating agents to higher ordered nucleic acids structures2021
    • Author(s)
      Fumi Nagatsugi, Madoka E. Hazemi, Norihiro Sato, Gen-ichiro Tsuji, Shunya Ishikawa, Mamiko Ozawa, Kazumitsu Onizuka
    • Organizer
      Pacifichem2021 New Challenge in Interdisciplinary and Multiscale Supramolecular Sciences
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K19038

  • [Presentation] Efficient alkene-alkene photo-cross-linking reaction on the flipping-out field in duplex DNA2021
    • Author(s)
      Ahmed Mostafa Abdelhady, Kazumitsu Onizuka, Sayaka Yajima, Kei Ishida, Eriko Mano, Fumi Nagatsugi
    • Organizer
      FIBER日本核酸化学会若手フォーラム
    • Data Source
      KAKENHI-PROJECT-21K19038

  • [Presentation] 標的核酸に対する選択的化学反応の開発2021
    • Author(s)
      永次 史
    • Organizer
      核酸化学若手フォーラム
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H02855

  • [Presentation] RNA結合性・アルキル化反応性の大規模解析技術開発2021
    • Author(s)
      鬼塚和光、小松リチャード馨、長澤瞭佑、Yutong Chen、宮下映見、石川竣也、小嶋かんな、村瀬裕貴、小澤眞美子、齊藤博英、永次史
    • Organizer
      第15回 バイオ関連化学シンポジウム
    • Data Source
      KAKENHI-PROJECT-21K19038

  • [Presentation] 標的核酸に対する選択的化学反応の開発2021
    • Author(s)
      永次　史
    • Organizer
      核酸化学若手フォーラム
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K19038

  • [Presentation] 副溝修飾アプタマーの探索を指向した置換基着脱型ヌクレオシドの開発2021
    • Author(s)
      岡村秀紀, 伊藤理奈, 佐藤健太, 永次史
    • Organizer
      日本ケミカルバイオロジー学会　第15回年会
    • Data Source
      KAKENHI-PROJECT-21K19038

  • [Presentation] Unnatural base pairs with spatially isolated hydrogen-bonding units in the DNA major groove2021
    • Author(s)
      Hidenori Okamura, Zhuoxin Dong, Giang Hoang Trinh, Fumi Nagatsugi
    • Organizer
      ISNAC2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H02855

  • [Presentation] RNA標的低分子創薬を目指したRNA－蛍光指示薬間相互作用大規模解析2021
    • Author(s)
      長澤瞭佑、鬼塚和光、小松リチャード馨、宮下映見、小澤眞美子、齊藤博英、永次史
    • Organizer
      第11回CSJ化学フェスタ2021
    • Data Source
      KAKENHI-PROJECT-20H02855

  • [Presentation] Unnatural base pairs with spatially isolated pseudo-nucleobases in the m+A25:D40ajor groove of DNA2021
    • Author(s)
      Hidenori Okamura, Zhuoxin Dong, Giang Hoang Trinh, Yoshiaki Masaki, Kohji Seio, Fumi Nagatsugi
    • Organizer
      Pacifichem2021 Satellite Symposium - Modified DNA and XNA for therapeutic application
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H02855

  • [Presentation] Efficient alkene-alkene photo-cross-linking reaction on the flipping-out field in duplex DNA2021
    • Author(s)
      Ahmed Mostafa Abdelhady, Kazumitsu Onizuka, Sayaka Yajima, Kei Ishida, Eriko Mano, Fumi Nagatsugi
    • Organizer
      FIBER日本核酸化学会若手フォーラム
    • Data Source
      KAKENHI-PROJECT-20H02855

  • [Presentation] 副溝修飾アプタマーの探索を指向した置換基着脱型人工核酸の開発2021
    • Author(s)
      岡村秀紀, 伊藤理奈, 佐藤健太, 永次史
    • Organizer
      第15回 バイオ関連化学シンポジウム
    • Data Source
      KAKENHI-PROJECT-21K19038

  • [Presentation] Novel reactivity modulable alkylating agents for higher-order structures of nucleic acids2021
    • Author(s)
      Yutong Chen, Kazumitsu Onizuka, Madoka E. Hazemi, Fumi Nagatsugi
    • Organizer
      有機合成化学夏季国際セミナー
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K19038

  • [Presentation] 標的核酸塩基のフリップアウトを誘起する人工核酸の開発とその機能化2021
    • Author(s)
      佐々木 まどか、鬼塚 和光、矢島 さやか、Ahmed Abdelhad、石田 圭、永次 史
    • Organizer
      日本化学会第101春季年会
    • Data Source
      KAKENHI-PROJECT-20H02855

  • [Presentation] Development of 2-amino-6-vinyl-7-deazapurine-deoxyriboside as an efficient cross-linking nucleoside for anti-miRNA therapy2021
    • Author(s)
      Nadia Syahla Soemawisastra, Hidenori Okamura, Fumi Nagatsugi
    • Organizer
      IS3NA-IRT Virtual Symposium 2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K19038

  • [Presentation] Efficient cross-linking reaction using base flip-inducing oligodeoxynucleotides2021
    • Author(s)
      Ahmed Mostafa Abdelhady, Kazumitsu Onizuka, Sayaka Yajima, Kei Ishida, Eriko Mano, Fumi Nagatsugi
    • Organizer
      IS3NA-IRT Virtual Symposium 2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H02855

  • [Presentation] Development of the reactive OFF-ON type alkylating agents to higher ordered nucleic acids structures2021
    • Author(s)
      Fumi Nagatsugi, Madoka E. Hazemi, Norihiro Sato, Gen-ichiro Tsuji, Shunya Ishikawa, Mamiko Ozawa, Kazumitsu Onizuka
    • Organizer
      Pacifichem2021 New Challenge in Interdisciplinary and Multiscale Supramolecular Sciences
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H02855

  • [Presentation] RNA 標的創薬を志向したRNA-小分子間相互作用大規模解析技術の開発2021
    • Author(s)
      鬼塚 和光、小松 馨、小嶋 かんな、村瀬 裕貴、石川 竣也、小澤 眞美子、長澤 瞭佑、宮下 映見、齊藤 博英、永次 史
    • Organizer
      日本薬学会第141年会
    • Data Source
      KAKENHI-PROJECT-20H02855

  • [Presentation] Creation of interstrand cross-linked nucleic acids and their application for miRNA inhibition2021
    • Author(s)
      Ahmed Mostafa Abdelhady, Kazumitsu Onizuka, Yu Hirano, Komatsu, Fumi Nagatsugi
    • Organizer
      ISNAC2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K19038

  • [Presentation] Unnatural base pairs with spatially-isolated nucleobase-like modules in the major groove of DNA2021
    • Author(s)
      Hidenori Okamura, Zhuoxin Dong, Giang Hoang Trinh, Fumi Nagatsugi
    • Organizer
      FIBER日本核酸化学会若手フォーラム
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K19038

  • [Presentation] RNA 結合性低分子探索に向けたRNA-蛍光指示薬間相互作用大規模解析2021
    • Author(s)
      長澤瞭佑、鬼塚和光、小松リチャード馨、宮下映見、小澤眞美子、齊藤博英、永次史
    • Organizer
      生体機能関連化学部会若手の会 第32回サマースクール
    • Data Source
      KAKENHI-PROJECT-21K19038

  • [Presentation] RNA 標的創薬を志向したRNA－蛍光指示薬間相互作用大規模解析2021
    • Author(s)
      長澤瞭佑、鬼塚和光、小松リチャード馨、宮下映見、小澤眞美子、齊藤博英、永次史
    • Organizer
      第32回万有仙台シンポジウム
    • Data Source
      KAKENHI-PROJECT-21K19038

  • [Presentation] RNA-小分子間化学シグナル大規模解析技術の展開2021
    • Author(s)
      鬼塚和光、小松リチャード馨、齊藤博英、永次史
    • Organizer
      「化学コミュニケーションのフロンティア」第8回公開シンポジウム
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H02855

  • [Presentation] Development of a photo-cyclization reaction producing phenanthridines in aqueous media2021
    • Author(s)
      飯田百香, 岡村秀紀, 金山唯, 永次史
    • Organizer
      令和３年度化学系学協会東北大会
    • Data Source
      KAKENHI-PROJECT-21K19038

  • [Presentation] RNAアルキル化反応の大規模解析技術開発2021
    • Author(s)
      鬼塚和光、小松リチャード馨、石川竣也、Yutong Chen、小嶋かんな、村瀬裕貴、長澤瞭佑、小澤眞美子、宮下映見、齊藤博英、永次史
    • Organizer
      日本ケミカルバイオロジー学会　第15回年会
    • Data Source
      KAKENHI-PROJECT-21K19038

  • [Presentation] Reactivity modulation of reactive OFF-ON type alkylating reagents for higher-ordered structures of nucleic acids2021
    • Author(s)
      Yutong Chen, Kazumitsu Onizuka, Madoka E. Hazemi, Fumi Nagatsugi
    • Organizer
      ISNAC2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K19038

  • [Presentation] 光感受性オキシムを用いた新規光環化反応の開発2021
    • Author(s)
      飯田 百香、岡村 秀紀、永次 史
    • Organizer
      日本化学会第101春季年会
    • Data Source
      KAKENHI-PROJECT-20H02855

  • [Presentation] RNA－蛍光指示薬間相互作用大規模解析に基づくRNA結合分子探索2021
    • Author(s)
      長澤瞭佑、鬼塚和光、小松リチャード馨、宮下映見、小澤眞美子、齊藤博英、永次史
    • Organizer
      第21回東北大学多元物質科学研究所研究発表会
    • Data Source
      KAKENHI-PROJECT-21K19038

  • [Presentation] Efficient cross-linking reaction using base flip-inducing oligodeoxynucleotides2021
    • Author(s)
      Ahmed Mostafa Abdelhady, Kazumitsu Onizuka, Sayaka Yajima, Kei Ishida, Eriko Mano, Fumi Nagatsugi
    • Organizer
      IS3NA-IRT Virtual Symposium 2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K19038

  • [Presentation] Structural optimization of alkynylated purine-pyridazine pairs for enhanced selectivity against natural nucleobases2021
    • Author(s)
      Zhuoxin Dong, Hidenori Okamura, Giang Hoang Trinh, Fumi Nagatsugi
    • Organizer
      FIBER日本核酸化学会若手フォーラム
    • Data Source
      KAKENHI-PROJECT-21K19038

  • [Presentation] Creation of interstrand cross-linked nucleic acids and their application for miRNA inhibition2021
    • Author(s)
      Ahmed Mostafa Abdelhady, Kazumitsu Onizuka, Yu Hirano, Komatsu, Fumi Nagatsugi
    • Organizer
      ISNAC2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H02855

  • [Presentation] Reactivity modulation of reactive OFF-ON type alkylating reagents for higher-ordered structures of nucleic acids2021
    • Author(s)
      Yutong Chen, Kazumitsu Onizuka, Madoka E. Hazemi, Fumi Nagatsugi
    • Organizer
      ISNAC2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H02855

  • [Presentation] Development of a photo-cyclization reaction producing phenanthridines in aqueous media2021
    • Author(s)
      飯田百香, 岡村秀紀, 金山唯, 永次史
    • Organizer
      令和３年度化学系学協会東北大会
    • Data Source
      KAKENHI-PROJECT-20H02855

  • [Presentation] Alkynylated purine-pyridazine base pairs with enhanced orthogonality by utilizing non-classical hydrogen bond2021
    • Author(s)
      Zhuoxin Dong, Hidenori Okamura, Fumi Nagatsugi
    • Organizer
      日本化学会第101春季年会
    • Data Source
      KAKENHI-PROJECT-20H02855

  • [Presentation] 化学修飾アプタマーの探索を指向した置換基着脱型ヌクレオシドの開発2021
    • Author(s)
      岡村 秀紀、伊藤 理奈、永次 史
    • Organizer
      日本薬学会第141年会
    • Data Source
      KAKENHI-PROJECT-20H02855

  • [Presentation] RNA 結合性低分子探索に向けたRNA-蛍光指示薬間相互作用大規模解析2021
    • Author(s)
      長澤瞭佑、鬼塚和光、小松リチャード馨、宮下映見、小澤眞美子、齊藤博英、永次史
    • Organizer
      生体機能関連化学部会若手の会 第32回サマースクール
    • Data Source
      KAKENHI-PROJECT-20H02855

  • [Presentation] RNA－蛍光指示薬間相互作用大規模解析に基づくRNA結合分子探索2021
    • Author(s)
      長澤瞭佑、鬼塚和光、小松リチャード馨、宮下映見、小澤眞美子、齊藤博英、永次史
    • Organizer
      第21回東北大学多元物質科学研究所研究発表会
    • Data Source
      KAKENHI-PROJECT-20H02855

  • [Presentation] Unnatural base pairs with spatially isolated hydrogen-bonding units in the DNA major groove2021
    • Author(s)
      Hidenori Okamura, Zhuoxin Dong, Giang Hoang Trinh, Fumi Nagatsugi
    • Organizer
      ISNAC2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K19038

  • [Presentation] Structural optimization of alkynylated purine-pyridazine pairs for enhanced selectivity against natural nucleobases2021
    • Author(s)
      Zhuoxin Dong, Hidenori Okamura, Giang Hoang Trinh, Fumi Nagatsugi
    • Organizer
      FIBER日本核酸化学会若手フォーラム
    • Data Source
      KAKENHI-PROJECT-20H02855

  • [Presentation] Reactivity modulation of reactive OFF-ON type G4-DNA alkylating reagents2021
    • Author(s)
      Yutong Chen, Kazumitsu Onizuka, Madoka Eurika Hazemi, Fumi Nagatsugi
    • Organizer
      日本化学会第101春季年会
    • Data Source
      KAKENHI-PROJECT-20H02855

  • [Presentation] Investigation of on-column Sonogashira coupling for structural optimization of alkynylated purine-pyridazine base pairs2021
    • Author(s)
      Giang Hoang Trinh, Hidenori Okamura, Fumi Nagatsugi
    • Organizer
      日本化学会第101春季年会
    • Data Source
      KAKENHI-PROJECT-20H02855

  • [Presentation] RNAの高次構造変化を誘起する新規低分子リガンドの開発2021
    • Author(s)
      村瀬 裕貴、永次 史、佐々木 茂貴
    • Organizer
      日本化学会第101春季年会
    • Data Source
      KAKENHI-PROJECT-20H02855

  • [Presentation] RNA－蛍光指示薬間相互作用大規模解析を利用したRNA結合性低分子の探索2021
    • Author(s)
      長澤瞭佑、鬼塚和光、小松リチャード馨、宮下映見、小澤眞美子、齊藤博英、永次史
    • Organizer
      令和３年度化学系学協会東北大会
    • Data Source
      KAKENHI-PROJECT-21K19038

  • [Presentation] RNA 標的創薬を志向したRNA－蛍光指示薬間相互作用大規模解析2021
    • Author(s)
      長澤瞭佑、鬼塚和光、小松リチャード馨、宮下映見、小澤眞美子、齊藤博英、永次史
    • Organizer
      第32回万有仙台シンポジウム
    • Data Source
      KAKENHI-PROJECT-20H02855

  • [Presentation] RNA結合分子のハイスループット探索に向けたRNA－蛍光指示薬間相互作用大規模解析2021
    • Author(s)
      長澤 瞭佑、鬼塚 和光、小松 馨、宮下 映見、小澤 眞美子、齊藤 博英、永次 史
    • Organizer
      日本化学会第101春季年会
    • Data Source
      KAKENHI-PROJECT-20H02855

  • [Presentation] Alkene-alkene photo-cross-linking reaction on the flipping-out field in duplex DNA2021
    • Author(s)
      AHMED MOSTAFA ABDELHADY, Kazumitsu Onizuka, Sayaka Yajima, Kei Ishida, Eriko Mano, Fumi Nagatsugi
    • Organizer
      日本化学会第101春季年会
    • Data Source
      KAKENHI-PROJECT-20H02855

  • [Presentation] RNA－蛍光指示薬間相互作用大規模解析を利用したRNA結合性低分子の探索2021
    • Author(s)
      長澤瞭佑、鬼塚和光、小松リチャード馨、宮下映見、小澤眞美子、齊藤博英、永次史
    • Organizer
      令和３年度化学系学協会東北大会
    • Data Source
      KAKENHI-PROJECT-20H02855

  • [Presentation] 副溝修飾アプタマーの探索を指向した置換基着脱型ヌクレオシドの開発2021
    • Author(s)
      岡村秀紀, 伊藤理奈, 佐藤健太, 永次史
    • Organizer
      日本ケミカルバイオロジー学会 第15回年会
    • Data Source
      KAKENHI-PROJECT-20H02855

  • [Presentation] RNAアルキル化反応の大規模解析技術開発2021
    • Author(s)
      鬼塚和光、小松リチャード馨、石川竣也、Yutong Chen、小嶋かんな、村瀬裕貴、長澤瞭佑、小澤眞美子、宮下映見、齊藤博英、永次史
    • Organizer
      日本ケミカルバイオロジー学会 第15回年会
    • Data Source
      KAKENHI-PROJECT-20H02855

  • [Presentation] Unnatural base pairs with spatially-isolated nucleobase-like modules in the major groove of DNA2021
    • Author(s)
      Hidenori Okamura, Zhuoxin Dong, Giang Hoang Trinh, Fumi Nagatsugi
    • Organizer
      FIBER日本核酸化学会若手フォーラム
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H02855

  • [Presentation] 化学修飾アプタマーの開発を指向した置換基着脱型ヌクレオシドの設計と合成2021
    • Author(s)
      岡村 秀紀、伊藤 理奈、永次 史
    • Organizer
      日本化学会第101春季年会
    • Data Source
      KAKENHI-PROJECT-20H02855

  • [Presentation] 副溝修飾アプタマーの探索を指向した置換基着脱型人工核酸の開発2021
    • Author(s)
      岡村秀紀, 伊藤理奈, 佐藤健太, 永次史
    • Organizer
      第15回 バイオ関連化学シンポジウム
    • Data Source
      KAKENHI-PROJECT-20H02855

  • [Presentation] ベルベリンによるRNA2次構造の認識機構の解析とRNAアルキル化剤への拡張2020
    • Author(s)
      遠藤玉樹, スタパチ サガー, チェン ユートン, 鬼塚和光, 永次 史, 杉本直己
    • Organizer
      第20回多元研発表会
    • Data Source
      KAKENHI-PROJECT-20H02855

  • [Presentation] Development of the novel artificial nucleic acids to induce the base flipping out2020
    • Author(s)
      YAJIMA, Sayaka; ONIZUKA, Kazumitsu; ISHIDA, Kei; NAGATSUGI, Fumi
    • Organizer
      日本化学会 第100春季年会
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] アプタマー探索適用を目指した新規修飾ヌクレオシドの開発2020
    • Author(s)
      伊藤理奈、 岡村秀紀、 永次 史
    • Organizer
      第31回万有仙台シンポジウム
    • Data Source
      KAKENHI-PROJECT-20H02855

  • [Presentation] 安定で直行性を持つ塩基対形成可能な認識部位を持つ人工塩基の開発2020
    • Author(s)
      岡村秀紀, ジャン・ホアン・トリン, ドン チョウシン, 永次 史
    • Organizer
      The 4th Symposium for The Core Research Cluster for Materials Science and the 3rd Symposium on International Joint Graduate Program in Materials Science
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H02855

  • [Presentation] 付加的な水素結合部位を付与したヌクレオシド類縁体による直行型塩基対形成2020
    • Author(s)
      岡村　秀紀・Trinh Hoang　Giang・永次　史
    • Organizer
      日本化学会 第100春季年会
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] 標的RNAに対して効率的架橋反応性を持つ人工核酸の開発2020
    • Author(s)
      永次 史, 阿部友亮, 山田 研, 福間清乃, 唐東来, 岡村秀紀
    • Organizer
      第69回高分子討論会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H02855

  • [Presentation] 核酸塩基フリップアウト場における特異な化学反応2020
    • Author(s)
      鬼塚 和光、石田 圭、矢島 さやか、間野 絵梨子、永次 史
    • Organizer
      日本薬学会 第140年会
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] 反応性オフーオン型のG4本鎖 DNAアルキル化剤の開発2020
    • Author(s)
      チェン ユートン、 鬼塚和光、 マドカ ハゼミ、 永次 史
    • Organizer
      第20回多元研発表会
    • Data Source
      KAKENHI-PROJECT-20H02855

  • [Presentation] 化学修飾アプタマーの探索を指向した新規人工ヌクレオシドの創製2020
    • Author(s)
      伊藤　理奈・岡村　秀紀・永次　史
    • Organizer
      日本化学会 第100春季年会
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] 官能基化された人工核酸塩基の開発2020
    • Author(s)
      岡村秀紀, 伊藤理奈, 永次 史
    • Organizer
      東北大学＆理化学研究所 連携シンポジウム
    • Data Source
      KAKENHI-PROJECT-20H02855

  • [Presentation] Development of the functional molecules for alkylating G-quadruplex2019
    • Author(s)
      S. Ishikawa, M. E. Hazemi, K.Onizuka, F.Nagatsugi
    • Organizer
      Tohoku University Campus Asia Program Summer School 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] 核酸高次構造選択的アルキル化のための反応性OFF-ON型反応素子の開発2019
    • Author(s)
      鬼塚和光、Madoka E. Hazemi、石川竣也、永次　史
    • Organizer
      日本ケミカルバイオロジー学会　第１4回年会
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] 遺伝子発現を制御する機能性中分子の創製2019
    • Author(s)
      永次　史
    • Organizer
      新学術領域成果報告会
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] 核酸高次構造選択的アルキル化反応は遺伝子発現を制御する2019
    • Author(s)
      鬼塚和光、ハゼミ・マドカ、石川俊也、永次　史、
    • Organizer
      第２２回生命化学研究会
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] G-clampによるグアニン認識を基本としたRNA高次構造結合性低分子リガンドの開発2019
    • Author(s)
      村瀬裕貴、永次　史
    • Organizer
      日本薬学会第139年会
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] 効率的遺伝子制御を目指した配座固定型架橋反応性オリゴヌクレオチドの開発2019
    • Author(s)
      8.永次　史、福間清乃、阿部友亮、山田　研、村瀬裕貴、岡村秀紀
    • Organizer
      第５回日本核酸医薬学会年会
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] Base flip-inducing oligo DNA and photo-crosslinking2019
    • Author(s)
      K.Onizuka, K. Ishida, E. Mano, F. Nagatsugi,
    • Organizer
      CISNAC 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] Selective Binding Molecules to Nucleic Acids in the Higher-Ordered Structures2019
    • Author(s)
      Fumi Nagatsugi, Hirotaka Murase, Kazumitsu Onizuka
    • Organizer
      Asian Chemical Biology Initiative 2019
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] Development of the alkylation reactions to the higher-ordered structures of nucleic acids2019
    • Author(s)
      K.Onizuka, M.E. Hazemi, N. Sato, G. Tsuji , S. Ishikawa, F. Nagatsugi
    • Organizer
      CISNAC 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] 付加的な水素結合ユニットを有するデュアルヘッド型人工塩基対の開発2019
    • Author(s)
      岡村秀紀、Trinh Hoang Giang、永次　史
    • Organizer
      第１３回バイオ関連化学シンポジウム
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] 標的核酸塩基のフリップアウトを誘起する人工核酸の開発と特異な光反応2019
    • Author(s)
      鬼塚 和光、石田　圭、間野絵梨子、永次 史
    • Organizer
      日本化学会第99春季年会
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] 高機能化遺伝子発現システムの構築を指向した新規人工塩基対の創製2019
    • Author(s)
      岡村秀紀、Trinh Hoang Giang、永次　史
    • Organizer
      第19回多元物質科学研究所研究発表会
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] Orthogonal base pair formation by nucleoside analogs bearing additional hydrogen-bonding units2019
    • Author(s)
      H. Okamura, G. H. Trinh, F. Nagatsugi
    • Organizer
      ISNAC 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] G4重鎖をアルキル化する機能性分子の開発2019
    • Author(s)
      石川俊也、Hazemi Eurika Madoka、鬼塚和光、永次　史
    • Organizer
      日本化学会第99春季年会
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] 反応性OFF-ON型核酸高次構造選択的アルキル化剤の開発2019
    • Author(s)
      鬼塚和光、Madoka E. Hazemi、石川竣也、永次　史
    • Organizer
      第１１５回有機合成化学シンポジウム
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] 遺伝子発現制御を目指した核酸の特殊反応場における選択的化学反応の開発2019
    • Author(s)
      永次　史
    • Organizer
      有機合成夏季セミナー　明日の有機合成化学
    • Invited
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] Reactive OFF-ON type alkylating agents for higher-ordered structures of nucleic acids2019
    • Author(s)
      F. Nagatsugi, M. HAZEMI, E. Ganbold, K. Onizuka
    • Organizer
      The 4th A3 Roundtable Meeting on Chemical Probe Research Hub, Sendai, Japan
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] Development of the effective alkylating probes for the higher-ordered structure of nucleic acids, Development of the effective alkylating probes for G-Quadruplex2019
    • Author(s)
      K.Onizuka, M.E. Hazemi, N. Sato, G. Tsuji, S. Ishikawa, F.Nagatsugi
    • Organizer
      27th FJS Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] Light-up型蛍光小分子に結合する核酸配列の最適化技術の確立と応用2019
    • Author(s)
      遠藤玉樹、村瀬裕貴、鬼塚和光、永次　史、杉本直己
    • Organizer
      第19回多元物質科学研究所研究発表会
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] 核酸塩基フリップアウト場における特異な光反応2019
    • Author(s)
      鬼塚 和光、石田　圭、間野　江梨子、永次　史
    • Organizer
      第１３回バイオ関連化学シンポジウム
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] Base-flip-inducing oligo DNA and photo-crosslinking on the flipping-out field2019
    • Author(s)
      K. Onizuka, K. Ishida, S. Yajima, E. Mano, F. Nagatsugi
    • Organizer
      ISNAC 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] Spontaneous pseudorotaxane formation targeting nucleic acids2018
    • Author(s)
      Kazumitsu Onizuka, Jumpei Matsuyama Takuya Miyashita, Yuuya Kawasaki, Kazunobu Igawa, Katsuhiko Tomooka, Fumi Nagatsugi
    • Organizer
      XXIII Round Table on Nucleosides, Nucleotides and Nucleic Acids Chemical Biology of Nucleic Acids
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] ビオチンをコンジュゲートした核酸結合性小分子の合成と結合RNA配列解析への展開2018
    • Author(s)
      小嶋 かんな・鬼塚 和光・丹野 宏亮・永次 史
    • Organizer
      日本化学会第98春季年会
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] Development of the effective alkylating probes for G-Quadruplex2018
    • Author(s)
      Fumi Nagatsugi, Norihiro Sato, Madoka Hazemi Eurika,Kazumitsu Onizuka
    • Organizer
      XXIII Round Table on Nucleosides, Nucleotides and Nucleic Acids Chemical Biology of Nucleic Acids
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] ビニルキナゾリノン誘導体によるG-四重鎖構造のアルキル化2018
    • Author(s)
      Madoka Eurika HAZEMI・ Kazumitsu ONIZUKA・Norihiro SATO ・Fumi NAGATSUGI
    • Organizer
      日本薬学会第１３８年会
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] 標的核酸塩基をフリップアウトさせる機能性核酸の開発2018
    • Author(s)
      石田　圭、鬼塚 和光、永次 史
    • Organizer
      第１２回バイオ関連化学シンポジウム
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] Development of small molecular G-clamp derivatives binding to RNA higher-order structure2018
    • Author(s)
      Hirotaka Murase, Fumi Nagatsugi
    • Organizer
      The 45th International Symposium on Nucleic Acids Chemistry
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] ヘアピンRNAに結合する1,3-ジアザフェノキサジン誘導体の開発2018
    • Author(s)
      村瀬 裕貴 ・ 永次 史
    • Organizer
      日本薬学会第１３８年会
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] 相補塩基のフリップアウトを誘起する人工核酸の開発2018
    • Author(s)
      石田 圭・鬼塚 和光・永次 史
    • Organizer
      日本化学会第98春季年会
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] 擬ロタキサン形成核酸の開発とその応用研究2018
    • Author(s)
      鬼塚 和光、松山 潤炳、宮下 卓也、河崎 悠也、井川 和宣、友岡 克彦、永次 史
    • Organizer
      第４回日本核酸医薬学会年会
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] Development of artificial nucleic acids to induce the base flipping out2018
    • Author(s)
      Kei Ishida, Kazumitsu Onizuka, and Fumi Nagatsugi
    • Organizer
      Tohoku University Campus Asia Program Summer School 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] 効率的遺伝子制御に向けた架橋反応性7-デアザ-6-ビニルグアニン誘導体の開発2018
    • Author(s)
      村瀬裕貴、福間清乃、阿部友亮、山田研、鬼塚和光、永次　史
    • Organizer
      第４回日本核酸医薬学会年会
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] RNAの非共有結合性蛍光ラベル化を可能にする蛍光ON型擬ロタキサン形成核酸の開発2018
    • Author(s)
      鬼塚和光、松山潤平、小澤眞美子、宮下卓也、河崎悠也、井川和亘、友岡克彦、吉田優、細谷孝充、永次 史
    • Organizer
      第18回多元物質科学研究所研究発表会
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] Development of the acyclic linked 7-deaza-6-vinyl guanine derivatives and Evaluation of the crosslinking reactivity2018
    • Author(s)
      Kiyono Fukuma, Hirotaka Murase, Yusuke Abe, Ken Yamada, Kazumitsu Onizuka, Fumi Nagatsugi
    • Organizer
      Tohoku University Campus Asia Program Summer School 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] RNA切断能を持つ機能性核酸の開発2018
    • Author(s)
      鬼塚 和光・田口 晃史・永次 史
    • Organizer
      日本化学会第98春季年会
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] 核酸高次構造アルキル化のための新規反応剤の開発2018
    • Author(s)
      鬼塚 和光、Hazemi E.Madoka, 丹野宏亮、石川俊也、佐藤憲大、永次　史
    • Organizer
      第１２回バイオ関連化学シンポジウム
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] Development of fluorescent probe for RNA higher-order structure2018
    • Author(s)
      Hirotaka Murase, Fumi Nagatsugi
    • Organizer
      XXIII Round Table on Nucleosides, Nucleotides and Nucleic Acids Chemical Biology of Nucleic Acids
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] Targeting RNA G-Quadruplex and KRas Protein-Protein Interaction Using Click chemistry2018
    • Author(s)
      Toan Khanh Le, Kazumitsu Onizuka, Junko Ohkanda, Fumi Nagatsugi
    • Organizer
      Tohoku University Campus Asia Program Summer School 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] 標的RNAを化学的に切断する機能性核酸の開発2018
    • Author(s)
      鬼塚 和光 ・ 田口 晃史 ・ 永次 史
    • Organizer
      日本薬学会第１３８年会
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] Synthesis of biotinylated nucleic acids binding molecules for the analysis of their binding RNA sequences2018
    • Author(s)
      Kanna Ojima, Kazumitsu Onizuka, Kousuke Tanno, Fumi Nagatsugi
    • Organizer
      Tohoku University Campus Asia Program Summer School 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] RNAの非共有結合性蛍光ラベル化を可能にする蛍光OFF/ON型擬ロタキサン形成核酸の開発2018
    • Author(s)
      松山 潤炳1・鬼塚 和光・宮下 卓也・河崎 悠也・井川 和宣・友岡 克彦・永次 史
    • Organizer
      日本化学会第98春季年会
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] Selective Binding Molecules to Nucleic Acids in the Higher-Ordered Structures2018
    • Author(s)
      Fumi Nagatsugi, HAZEMI, Madoka Eurika, Akira Usami, Norihiro Sato, Kazumitsu Onizuka
    • Organizer
      The 3rd A3 Roundtable Meeting on Chemical Probe Research Hub
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] 高い架橋反応性を持つ7-デアザ-6-ビニルグアニン誘導体の開発2018
    • Author(s)
      福間 清乃 ・ 阿部 友亮 ・ 山田 研 ・鬼塚 和光・ 村瀬 裕貴・ 永次 史
    • Organizer
      日本薬学会第１３８年会
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] Development of fluorescence OFF/ON type pseudorotaxane-forming nucleic acids for noncovalent labeling of RNA2018
    • Author(s)
      Jumpei Matsuyama, Kazumitsu Onizuka, Takuya Miyashita, Yuuya Kawasaki, Kazunobu Igawa, Katsuhiko Tomooka, Fumi Nagatsugi
    • Organizer
      Tohoku University Campus Asia Program Summer School 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] Development of the Cross-linkable Oligonucleotides for the Control of Gene Expression2018
    • Author(s)
      Fumi Nagatsugi, Ken Yamada, Yusuke Abe, Kiyono Fukuma, Hirotaka Murase
    • Organizer
      IKCOC-14
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] Spontaneous pseudorotaxane formation targeting nucleic acids and fluorogenic click chemistry2018
    • Author(s)
      K.Onizuka, J. Matsuyama, T.Miyashita, Y. Kawasaki, K. Igawa, K.Tomooka, F. Nagatsugi
    • Organizer
      The 45th International Symposium on Nucleic Acids Chemistry
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] 1，3－ジアザフェノキサジン環によるグアニン認識を利用したRNA高次構造検出プローブの開発2018
    • Author(s)
      村瀬裕貴、永次　史
    • Organizer
      日本ケミカルバイオロジー学会　第１３回年会
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] ビオチンを修飾した核酸結合性分子の合成と結合RNA配列解析への展開2018
    • Author(s)
      小嶋かんな、鬼塚和光、丹野宏亮、永次　史
    • Organizer
      日本ケミカルバイオロジー学会　第１３回年会
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] フリップアウト能を持つ人工核酸の開発と特異な化学反応の検討2018
    • Author(s)
      石田　圭、鬼塚 和光、間野絵梨子、永次 史
    • Organizer
      第18回多元物質科学研究所研究発表会
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] 疾患関連核酸高次構造を標的とした反応性プローブの開発2018
    • Author(s)
      永次　史
    • Organizer
      平成30年度化学系学協会東北大会
    • Invited
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] 核酸高次構造をアルキル化する中分子の開発2017
    • Author(s)
      永次　史
    • Organizer
      日本薬学会第１３７年会（仙台）
    • Place of Presentation
      仙台国際センター（宮城県仙台市）
    • Year and Date
      2017-03-24
    • Invited
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] T-Tミスマッチ構造を選択的にアルキル化する小分子の開発2017
    • Author(s)
      鬼塚　和光、宇佐美　彬、小林倫仁、Madoka Eurika Hazemi、永次　史
    • Organizer
      日本ケミカルバイオロジー学会　第１２回年会
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] Development of novel G-quadruplex alkylating agents2017
    • Author(s)
      M. E. Hazemi, K. Onizuka, T. Kobayashi, A. Usami, N. Sato, F. Nagatsugi
    • Organizer
      ISBC2017
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] Selective G-quadruplex alkylation by vinyl triazine derivatives2017
    • Author(s)
      HAZEMI, Madoka Eurika; USAMI, Akira; KOBAYASHI, Tomohito; SATO, Norihiro; ONIZUKA, Kazumitsu; NAGATSUGI, Fumi
    • Organizer
      日本化学会第９７春季年会
    • Place of Presentation
      慶應義塾大学　日吉キャンパス（神奈川県横浜市）
    • Year and Date
      2017-03-14
    • Data Source
      KAKENHI-PROJECT-15K14975

  • [Presentation] 動的分子認識を指向した蛍光性ベンゾオキサボロールの合成及びcis-1,2ジオール認識能評価2017
    • Author(s)
      小西紗枝、永次　史、林田　修、草野修平
    • Organizer
      第17回多元物質科学研究所研究発表会
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] 核酸高次構造をアルキル化する中分子の開発～生体分子に対する選択的化学反応の開発～2017
    • Author(s)
      永次　史
    • Organizer
      第４回　新学術領域研究　反応集積化が導く中分子戦略：高次生物機能分子の創製、若手シンポジウム
    • Invited
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] Development of G-quadruplex Alkylating Small Molecules2017
    • Author(s)
      M. E. Hazemi, K. Onizuka, T. Kobayashi, A. Usami, N. Sato, F. Nagatsugi
    • Organizer
      The 44th International Symposium on Nucleic Acids Chemistry
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] Development of new efficient alkylating probes targeting double stranded DNA containing an abasic-site2017
    • Author(s)
      K. Tanno, K. Yamada, Y. Sasaki, N. Sato, K. Onizuka F. Nagatsugi
    • Organizer
      Tohoku University Campus Asia Program Summer School 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] DNA中のT-Tミスマッチ構造を選択的にアルキル化する小分子の開発2017
    • Author(s)
      鬼塚　和光、宇佐美　彬、山置佑大、小林倫仁、Madoka Eurika Hazemi、千国友子、片平　正人、永次　史
    • Organizer
      第１１回バイオ関連化学シンポジウム
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] RNAの非共有結合性蛍光ラベル化を可能にする蛍光ON型擬ロタキサン形成核酸の開発2017
    • Author(s)
      松山潤平、鬼塚和光、宮下卓也、河崎悠也、井川和宣、友岡克彦、永次 史
    • Organizer
      第17回多元物質科学研究所研究発表会
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] Mechanistic study of pseudorotaxane formation via the slipping process targeting on nucleic acids2017
    • Author(s)
      ONIZUKA, Kazumitsu; CHIKUNI, Tomoko; MIYASHITA, Takuya; NAGATSUGI, Fumi
    • Organizer
      日本化学会第９７春季年会
    • Place of Presentation
      慶應義塾大学　日吉キャンパス（神奈川県横浜市）
    • Year and Date
      2017-03-14
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] Spontaneous pseudorotaxane formation methods targeting on RNA2017
    • Author(s)
      K. Onizuka, T. Miyashita, T. Chikuni, F. Nagatsugi
    • Organizer
      The 43rd Naito conference on noncoding RNA: biology, chemistry, and diseases
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] Development of the Chemical Tools for the Alkylation to Nucleic Acid Binding Protein2017
    • Author(s)
      F. Nagatsugi, K. Odaira, K. Yamada
    • Organizer
      Asian Chemical Biology Initiative (ACBI) 2017
    • Place of Presentation
      Ho-chi-minh, Vietnam
    • Year and Date
      2017-01-20
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] Development of the Reactive Probes for Selective Alkylation to G4 Structure2017
    • Author(s)
      F. Nagatsugi
    • Organizer
      Asian Chemical Biology Initiative
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] トリアジン型シクロファンの開発と分子認識2017
    • Author(s)
      草野修平、小西紗枝、永次　史、林田　修
    • Organizer
      第17回多元物質科学研究所研究発表会
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] 脱塩基部位を持つ２本鎖DNAを標的とした効率的アルキル化プローブの開発2017
    • Author(s)
      丹野　宏亮・山田　研・佐々木　欣宏・佐藤　憲大・鬼塚　和光・永次　史
    • Organizer
      日本化学会第９７春季年会
    • Place of Presentation
      慶應義塾大学　日吉キャンパス（神奈川県横浜市）
    • Year and Date
      2017-03-14
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] Investigation of linker structures to functionalize pseudorotaxane-forming oligo nucleic acids2017
    • Author(s)
      TAGUCHI, Akifumi; ONIDUKA, Kazumitu; MIYASHITA, Takuya; NAGATSUGI, Fumi
    • Organizer
      日本化学会第９７春季年会
    • Place of Presentation
      慶應義塾大学　日吉キャンパス（神奈川県横浜市）
    • Year and Date
      2017-03-14
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] Development of the Reactive Oligonucleotides for the Control of Gene Expression2017
    • Author(s)
      F. Nagatsugi, K. Yamada, Y. Abe, S. Kusano
    • Organizer
      26th FJS symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] 脱塩基部位を持つ２本鎖DNAを標的とした効率的アルキル化プローブの開発2017
    • Author(s)
      丹野　宏亮・山田　研・佐々木　欣宏・佐藤　憲大・鬼塚　和光・永次　史
    • Organizer
      日本化学会第９７春季年会
    • Place of Presentation
      慶應義塾大学　日吉キャンパス（神奈川県横浜市）
    • Year and Date
      2017-03-14
    • Data Source
      KAKENHI-PROJECT-15K14975

  • [Presentation] 環状化核酸を用いたスリッピングによる擬ロタキサン構造形成のメカニズム研究2017
    • Author(s)
      鬼塚和光、千国友子、宮下卓也、永次　史
    • Organizer
      日本薬学会第１３７年会（仙台）
    • Place of Presentation
      東北大学川内キャンパス（宮城県仙台市）
    • Year and Date
      2017-03-24
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] The development of small molecules binding to the hairpin RNA structur2017
    • Author(s)
      H. Murase, F.Nagatsugi
    • Organizer
      ISBC2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] 核酸高次構造をアルキル化する中分子の開発2017
    • Author(s)
      永次　史
    • Organizer
      日本薬学会第１３７年会（仙台）
    • Place of Presentation
      仙台国際センター（宮城県仙台市）
    • Year and Date
      2017-03-24
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K14975

  • [Presentation] 核酸医薬の修飾技術動向2017
    • Author(s)
      永次　史
    • Organizer
      技術情報協会セミナー
    • Invited
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] 環状化核酸を用いたスリッピングによる擬ロタキサン構造形成のメカニズム研究2017
    • Author(s)
      鬼塚和光、千国友子、宮下卓也、永次　史
    • Organizer
      日本薬学会第１３７年会（仙台）
    • Place of Presentation
      東北大学川内キャンパス（宮城県仙台市）
    • Year and Date
      2017-03-24
    • Data Source
      KAKENHI-PROJECT-15K14975

  • [Presentation] 核酸結合蛋白質に対する新規架橋反応性核酸の開発2017
    • Author(s)
      永次　史，小平 健太,　山田　研
    • Organizer
      第３回日本核酸医薬学会年会
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] Selective G-quadruplex alkylation by vinyl triazine derivatives2017
    • Author(s)
      HAZEMI, Madoka Eurika; USAMI, Akira; KOBAYASHI, Tomohito; SATO, Norihiro; ONIZUKA, Kazumitsu; NAGATSUGI, Fumi
    • Organizer
      日本化学会第９７春季年会
    • Place of Presentation
      慶應義塾大学　日吉キャンパス（神奈川県横浜市）
    • Year and Date
      2017-03-14
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] Mechanistic study of pseudorotaxane formation via the slipping process targeting on nucleic acids2017
    • Author(s)
      ONIZUKA, Kazumitsu; CHIKUNI, Tomoko; MIYASHITA, Takuya; NAGATSUGI, Fumi
    • Organizer
      日本化学会第９７春季年会
    • Place of Presentation
      慶應義塾大学　日吉キャンパス（神奈川県横浜市）
    • Year and Date
      2017-03-14
    • Data Source
      KAKENHI-PROJECT-15K14975

  • [Presentation] Development of artificial oligonucleotides with the RNA- cleaving ability2017
    • Author(s)
      A. Taguchi, K. Onizuka, F. Nagatsugi
    • Organizer
      Tohoku University Campus Asia Program Summer School 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] Development of the Chemical Tools for the Alkylation to Nucleic Acid Binding Protein2017
    • Author(s)
      F. Nagatsugi, K. Odaira, K. Yamada
    • Organizer
      Asian Chemical Biology Initiative (ACBI) 2017
    • Place of Presentation
      Ho-chi-minh, Vietnam
    • Year and Date
      2017-01-20
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K14975

  • [Presentation] Investigation of linker structures to functionalize pseudorotaxane-forming oligo nucleic acid2017
    • Author(s)
      TAGUCHI, Akifumi; ONIDUKA, Kazumitu; MIYASHITA, Takuya; NAGATSUGI, Fumi
    • Organizer
      日本化学会第９７春季年会
    • Place of Presentation
      慶應義塾大学　日吉キャンパス（神奈川県横浜市）
    • Year and Date
      2017-03-14
    • Data Source
      KAKENHI-PROJECT-15K14975

  • [Presentation] 効率的遺伝子発現制御を目指した核酸をテンプレートにした選択的化学反応の開発2017
    • Author(s)
      永次　史
    • Organizer
      第29回万有札幌シンポジウム
    • Invited
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] 高効率遺伝子発現制御を指向した、架橋反応性7-デアザ-6-ビニルグアニン誘導体の開発2017
    • Author(s)
      福間清乃、阿部友亮、山田研、鬼塚和光、村瀬裕貴、永次　史
    • Organizer
      第１１回バイオ関連化学シンポジウム
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] 遺伝子発現を制御する機能性中分子の創製2017
    • Author(s)
      永次　史
    • Organizer
      第４回　新学術領域研究　反応集積化が導く中分子戦略：高次生物機能分子の創製　成果報告会
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] Spontaneous pseudorotaxane formation targeting RNA2017
    • Author(s)
      K. Onizuka, J. Matsuyama, T. Miyashita, Y. Kawasaki, K. Igawa, K. Tomooka, F. Nagatsugi
    • Organizer
      ISBC2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] 核酸高次構造をアルキル化する中分子の開発2017
    • Author(s)
      永次　史
    • Organizer
      アライアンス医療材料・デバイス・システムグループG3 分科会
    • Invited
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] Development of the New Probes for the Selective Chemical Modification to Higher Ordered Structured Nucleic Acids2016
    • Author(s)
      Fumi Nagatsugi
    • Organizer
      Asian Chemical Biology Initiative 2016
    • Place of Presentation
      Jakarta, Indonesia
    • Year and Date
      2016-01-30
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] Deveropment of psedorotaxane-forming oligonucleotides aiming at translational regulation2016
    • Author(s)
      T. Miyashita, K. Onizuka, F. Nagatsugi
    • Organizer
      Tohoku University Campus Asia Program Summer School
    • Place of Presentation
      Tohoku Univ. Sendai, Japan
    • Year and Date
      2016-08-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] DNA/RNAを標的とした擬ロタキサン形成オリゴDNAの構造最適化2016
    • Author(s)
      宮下　卓也、鬼塚　和光、永次　史
    • Organizer
      日本ケミカルバイオロジー学会　第11回年会
    • Place of Presentation
      京都テルサ（京都府京都市）
    • Year and Date
      2016-06-10
    • Data Source
      KAKENHI-PROJECT-15K14975

  • [Presentation] 核酸を標的とした擬ロタキサン形成オリゴ核酸の構造最適化2016
    • Author(s)
      鬼塚和光、宮下卓也、雨宮拓哉、永次　史
    • Organizer
      日本薬学会１３６年会
    • Place of Presentation
      パシフィコ横浜、神奈川
    • Year and Date
      2016-03-26
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] 架橋２重鎖を用いた酵素的DNA伸長反応の阻害2016
    • Author(s)
      山田　研、永次　史
    • Organizer
      日本化学会第９６春季年会
    • Place of Presentation
      同志社大学、京都
    • Year and Date
      2016-03-24
    • Data Source
      KAKENHI-PROJECT-15K14975

  • [Presentation] Development of Middle Molecular Probes for the Selective Chemical Modification to Higher-Order Structures in RNA2016
    • Author(s)
      A. Usami, T. Kobayashi, M. E. Hazemi, N. Sato, K. Onizuka, F. Nagatsugi
    • Organizer
      Tohoku University Campus Asia Program Summer School
    • Place of Presentation
      Tohoku Univ. Sendai, Japan
    • Year and Date
      2016-08-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] Synthesis of natural-like cross-linked duplex RNA and its properties2016
    • Author(s)
      M.E. Hazemi, K. Onizuka, K. Yamada, F. Nagatsugi
    • Organizer
      The 43th International Symposium on Nucleic Acids Chemistry
    • Place of Presentation
      Kumamoto univ., Kumamoto, Japan
    • Year and Date
      2016-09-27
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K14975

  • [Presentation] 架橋２重鎖を用いた酵素的DNA伸長反応の阻害2016
    • Author(s)
      山田　研、永次　史
    • Organizer
      日本化学会第９６春季年会
    • Place of Presentation
      同志社大学、京都
    • Year and Date
      2016-03-24
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] 核酸結合性タンパク質を標的とした新規架橋反応性塩基の合成と評価2016
    • Author(s)
      小平 健太、石山 翔午、山田 研、永次 史
    • Organizer
      第２７回万有シンポジウム
    • Place of Presentation
      仙台国際センター（宮城県仙台市）
    • Data Source
      KAKENHI-PROJECT-15K14975

  • [Presentation] 翻訳制御を指向した擬ロタキサン形成オリゴ核酸の開発2016
    • Author(s)
      鬼塚　和光、宮下　卓也、永次　史
    • Organizer
      第２回日本核酸医薬学会年会
    • Place of Presentation
      東京理科大学葛飾キャンパス図書館（東京都葛飾区）大ホール
    • Year and Date
      2016-11-15
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] 脱塩基部位を持つ２本鎖DNA選択的アルキル化プローブの開発2016
    • Author(s)
      丹野宏亮、山田　研、佐々木欣宏、佐藤憲大、永次 史
    • Organizer
      第16回多元物質科学研究所研究発表会
    • Place of Presentation
      東北大学片平キャンパス・さくらホール（宮城県仙台市）
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] Deveropment of psedorotaxane-forming oligonucleotides aiming at translational regulation2016
    • Author(s)
      T. Miyashita, K. Onizuka, F. Nagatsugi
    • Organizer
      Tohoku University Campus Asia Program Summer School 2016
    • Place of Presentation
      Tohoku Univ. Sendai, Japan
    • Year and Date
      2016-08-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K14975

  • [Presentation] Preparation of “Cross-Linkable duplex” using the Oligonucleotide Containing 4-amino-2-oxo-6-vinyl-1,3,5-triazine2016
    • Author(s)
      F. Nagatsugi, K. Odaira, K. Yamada
    • Organizer
      The First A3 Roundtable Meeting on Chemical Probe Research Hub
    • Place of Presentation
      Hotel LEOPALACE Hakata, Fukuoka Japan
    • Year and Date
      2016-09-22
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] Preparation of “Cross-Linkable duplex” using the Oligonucleotide Containing 4-amino-2-oxo-6-vinyl-1,3,5-triazine2016
    • Author(s)
      F. Nagatsugi, K. Odaira, K. Yamada
    • Organizer
      The First A3 Roundtable Meeting on Chemical Probe Research Hub
    • Place of Presentation
      Hotel LEOPALACE Hakata, Fukuoka Japan
    • Year and Date
      2016-09-22
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K14975

  • [Presentation] Development of the Middle-size Molecules for Alkylation to Highly Ordered Structures of Nucleic Acids2016
    • Author(s)
      F. Nagatsugi
    • Organizer
      The 2nd International Symposium on Middle Molecular Strategy
    • Place of Presentation
      Senri Life Science Center, Osaka, Japan
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] 脱塩基部位を持つ２本鎖DNA選択的アルキル化プローブの開発2016
    • Author(s)
      丹野宏亮、山田　研、佐々木欣宏、佐藤憲大、永次 史
    • Organizer
      第16回多元物質科学研究所研究発表会
    • Place of Presentation
      東北大学片平キャンパス・さくらホール（宮城県仙台市）
    • Data Source
      KAKENHI-PROJECT-15K14975

  • [Presentation] Synthesis of a New Cross-Linkable Oligonucleotides having 4-Amino-6-Oxo-2-Vinyl-Triazine2016
    • Author(s)
      K. Yamada, K. Odaira, S. Ishiyama, F. Nagatsugi
    • Organizer
      XXII Round Table on Nucleosides, Nucleotides and Nucleic Acids Chemical Biology of Nucleic Acids
    • Place of Presentation
      Paris, France
    • Year and Date
      2016-07-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K14975

  • [Presentation] 核酸結合性タンパク質を標的とした新規架橋反応性塩基の合成と評価2016
    • Author(s)
      小平 健太、石山 翔午、山田 研、永次 史
    • Organizer
      第２７回万有シンポジウム
    • Place of Presentation
      仙台国際センター（宮城県仙台市）
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] Synthesis of a New Cross-Linkable Oligonucleotides having 4-Amino-6-Oxo-2-Vinyl-Triazine2016
    • Author(s)
      K. Yamada, K. Odaira, S. Ishiyama, F. Nagatsugi
    • Organizer
      XXII Round Table on Nucleosides, Nucleotides and Nucleic Acids Chemical Biology of Nucleic Acids
    • Place of Presentation
      Paris, France
    • Year and Date
      2016-07-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] Development of the New Probes for the Selective Chemical Modification to Higher Ordered Structured Nucleic Acids2016
    • Author(s)
      Fumi Nagatsugi
    • Organizer
      Asian Chemical Biology Initiative 2016
    • Place of Presentation
      Jakarta, Indonesia
    • Year and Date
      2016-01-30
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] U-Uミスマッチ構造選択的な化学修飾を目指した中分しプローブの開発2016
    • Author(s)
      宇佐美 彬、小林 倫仁、Hazemi Eurika Madoka、鬼塚 和光、永次 史
    • Organizer
      第１０回バイオ関連化学シンポジウム
    • Place of Presentation
      石川県立音楽堂もてなしドーム（石川県金沢市）
    • Year and Date
      2016-09-07
    • Data Source
      KAKENHI-PROJECT-15K14975

  • [Presentation] Development of the Chemical Tools for the Alkylation to Nucleic Acid Binding Protein2016
    • Author(s)
      F. Nagatsugi, K. Odaira, K. Yamada
    • Organizer
      The Fourth Asian Chemical Biology Conference　(ACBC2016)
    • Place of Presentation
      85 Sky Tower Hotel, Kaohsiung, TAIWAN
    • Year and Date
      2016-11-28
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K14975

  • [Presentation] U-Uミスマッチ構造選択的な化学修飾を目指した中分しプローブの開発2016
    • Author(s)
      宇佐美 彬、小林 倫仁、Hazemi Eurika Madoka、鬼塚 和光、永次 史
    • Organizer
      第１０回バイオ関連化学シンポジウム
    • Place of Presentation
      石川県立音楽堂もてなしドーム（石川県金沢市）
    • Year and Date
      2016-09-07
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] Structural optimization of pseudorotaxane-forming oligoDNA targeting on nucleic acids2016
    • Author(s)
      K. Onizuka, Miyashita, T., F. Nagatsugi
    • Organizer
      The 43th International Symposium on Nucleic Acids Chemistry
    • Place of Presentation
      Kumamoto Univ., Kumamoto, Japan
    • Year and Date
      2016-09-27
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] Synthesis of Middle Molecular Probes for theSelective Chemical Modification to Higher-Order Structures in RNA2016
    • Author(s)
      A. Usami, T. Kobayashi, M. E. Hazemi, N. Sato, K. Onizuka, F. Nagatsugi
    • Organizer
      ISONIS 10
    • Place of Presentation
      Awajishima　Hyogo,Yumebutai, International Conference center
    • Year and Date
      2016-11-18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] 翻訳制御を指向した擬ロタキサン形成オリゴ核酸の開発2016
    • Author(s)
      鬼塚　和光、宮下　卓也、永次　史
    • Organizer
      第２回日本核酸医薬学会年会
    • Place of Presentation
      東京理科大学葛飾キャンパス図書館大ホール（東京都葛飾区）
    • Year and Date
      2016-11-15
    • Data Source
      KAKENHI-PROJECT-15K14975

  • [Presentation] U-Uミスマッチ構造を選択的に化学修飾する小分子プローブの開発2016
    • Author(s)
      宇佐美　彬、小林倫仁、佐藤憲大、鬼塚和光、永次　史
    • Organizer
      日本化学会第９６春季年会
    • Place of Presentation
      同志社大学、京都
    • Year and Date
      2016-03-24
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] 標的核酸に対して自発的に擬ロタキサン構造を形成する人工核酸の開発2016
    • Author(s)
      鬼塚　和光、宮下　卓也、永次　史
    • Organizer
      第１０回バイオ関連化学シンポジウム
    • Place of Presentation
      石川県立音楽堂もてなしドーム（石川県金沢市）
    • Year and Date
      2016-09-07
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] Synthesis of Middle Molecular Probes for the Selective Chemical Modification to Higher-Order Structures in RNA2016
    • Author(s)
      A. Usami, T. Kobayashi, M. E. Hazemi, N. Sato, K. Onizuka, F. Nagatsugi
    • Organizer
      ISONIS 10
    • Place of Presentation
      Hyogo, Awajishima-shi, 　yumebtai international conference center
    • Year and Date
      2016-11-18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K14975

  • [Presentation] U-Uミスマッチ構造を選択的に化学修飾する小分子プローブの開発2016
    • Author(s)
      宇佐美　彬、小林倫仁、佐藤憲大、鬼塚和光、永次　史
    • Organizer
      日本化学会第９６春季年会
    • Place of Presentation
      同志社大学、京都
    • Year and Date
      2016-03-24
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] 核酸を標的とした擬ロタキサン形成オリゴ核酸の構造最適化2016
    • Author(s)
      鬼塚和光、宮下卓也、雨宮拓哉、永次　史
    • Organizer
      日本薬学会１３６年会
    • Place of Presentation
      パシフィコ横浜、神奈川
    • Year and Date
      2016-03-26
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] 核酸結合性蛋白質との架橋反応を目指したビニルトリアジン誘導体の開発2016
    • Author(s)
      山田　研、小平 健太、石山 翔午、鬼塚和光、永次　史
    • Organizer
      日本ケミカルバイオロジー学会　第11回年会
    • Place of Presentation
      京都テルサ（京都府京都市）
    • Year and Date
      2016-06-10
    • Data Source
      KAKENHI-PROJECT-15K14975

  • [Presentation] Development of the Chemical Tools for the Alkylation to Nucleic Acid Binding Protein2016
    • Author(s)
      F. Nagatsugi, K. Odaira, K. Yamada
    • Organizer
      The Fourth Asian Chemical Biology Conference　(ACBC2016)
    • Place of Presentation
      85 Sky Tower Hotel, Kaohsiung, TAIWAN
    • Year and Date
      2016-11-28
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] Development of Middle Molecular Probes for the Selective Chemical Modification to Higher-Order Structures in RNA2016
    • Author(s)
      A. Usami, T. Kobayashi, M. E. Hazemi, N. Sato, K. Onizuka, F. Nagatsugi
    • Organizer
      Tohoku University Campus Asia Program Summer School 2016
    • Place of Presentation
      Tohoku Univ. Sendai, Japan
    • Year and Date
      2016-08-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K14975

  • [Presentation] Development of the Middle-size Molecules for Alkylation to Highly Ordered Structures of Nucleic Acids2016
    • Author(s)
      F. Nagatsugi
    • Organizer
      The 2nd International Symposium on Middle Molecular Strategy
    • Place of Presentation
      Senri Life Science Center, Osaka, Japan
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K14975

  • [Presentation] Selective Reactions to Nucleic Acids with Higher Ordered Structure2016
    • Author(s)
      F. Nagatsugi, N. Sato,　Kobayashi, Y. Sasaki, K.Onizuka, K. Yamada
    • Organizer
      12 th International, Symposium on Organic Reactions
    • Place of Presentation
      Kyoto Terrsa, Kyoto, Japan
    • Year and Date
      2016-04-21
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] Synthesis of a new cross-linkable nucleic acid derivative targeting nucleic acid binding proteins2016
    • Author(s)
      K. Odaira, S. Ishiyama, K. Yamada, F. Nagatsugi
    • Organizer
      Tohoku University Campus Asia Program Summer School 2016
    • Place of Presentation
      Tohoku Univ. Sendai, Japan
    • Year and Date
      2016-08-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K14975

  • [Presentation] Synthesis of the middle-size molecules for alkylation to highly ordered structures of nucleic acids2016
    • Author(s)
      N. Sato, Y. Sasaki, G.Tsuji, A.Usami, K. Onizuka, K.Yamada and F. Nagatsugi
    • Organizer
      XXII Round Table on Nucleosides, Nucleotides and Nucleic Acids Chemical Biology of Nucleic Acids
    • Place of Presentation
      Paris, France
    • Year and Date
      2016-07-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] Synthesis of Natural-like Cross-linked duplex RNA for Biochemical Studies2016
    • Author(s)
      M. H. Eurika, K. Onizuka, K. Yamada, F. Nagatsugi
    • Organizer
      Tohoku University Campus Asia Program Summer School
    • Place of Presentation
      Tohoku Univ. Sendai, Japan
    • Year and Date
      2016-08-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] Selective Reactions to Nucleic Acids with Higher Ordered Structure2016
    • Author(s)
      F. Nagatsugi, N. Sato,　Kobayashi, Y. Sasaki, K.Onizuka, K. Yamada
    • Organizer
      12 th International, Symposium on Organic Reactions
    • Place of Presentation
      Kyoto Terrsa, Kyoto, Japan
    • Year and Date
      2016-04-21
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K14975

  • [Presentation] 核酸結合性蛋白質との架橋反応を目指したビニルトリアジン誘導体の開発2016
    • Author(s)
      山田　研、小平 健太、石山 翔午、鬼塚和光、永次　史
    • Organizer
      日本ケミカルバイオロジー学会　第11回年会
    • Place of Presentation
      京都テルサ（京都府京都市）
    • Year and Date
      2016-06-10
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] 核酸結合性蛋白質を標的とした新規架橋反応性核酸誘導体の合成2016
    • Author(s)
      小平健太、石山 翔午、山田 研、永次 史
    • Organizer
      日本化学会第９６春季年会
    • Place of Presentation
      同志社大学、京都
    • Year and Date
      2016-03-24
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] Synthesis of natural-like cross-linked duplex RNA and its properties2016
    • Author(s)
      M.E. Hazemi, K. Onizuka, K. Yamada, F. Nagatsugi
    • Organizer
      The 43th International Symposium on Nucleic Acids Chemistry
    • Place of Presentation
      Kumamoto Univ., Kumamoto, Japan
    • Year and Date
      2016-09-27
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] DNA/RNAを標的とした擬ロタキサン形成オリゴDNAの構造最適化2016
    • Author(s)
      宮下　卓也、鬼塚　和光、永次　史
    • Organizer
      日本ケミカルバイオロジー学会　第11回年会
    • Place of Presentation
      京都テルサ（京都府京都市）
    • Year and Date
      2016-06-10
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] 核酸結合性蛋白質を標的とした新規架橋反応性核酸誘導体の合成2016
    • Author(s)
      小平健太、石山 翔午、山田 研、永次 史、
    • Organizer
      日本化学会第９６春季年会
    • Place of Presentation
      同志社大学、京都
    • Year and Date
      2016-03-24
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] Synthesis of Natural-like Cross-linked duplex RNA for Biochemical Studies2016
    • Author(s)
      M. H. Eurika, K. Onizuka, K. Yamada, F. Nagatsugi
    • Organizer
      Tohoku University Campus Asia Program Summer School 2016
    • Place of Presentation
      Tohoku Univ. Sendai, Japan
    • Year and Date
      2016-08-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K14975

  • [Presentation] Structural optimization of pseudorotaxane-forming oligoDNA targeting on nucleic acids2016
    • Author(s)
      K. Onizuka, Miyashita, T., F. Nagatsugi
    • Organizer
      The 43th International Symposium on Nucleic Acids Chemistry
    • Place of Presentation
      Kumamoto univ., Kuamamoto, Japan
    • Year and Date
      2016-09-27
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K14975

  • [Presentation] Synthesis of the middle-size molecules for alkylation to highly ordered structures of nucleic acids2016
    • Author(s)
      N. Sato, Y. Sasaki, G.Tsuji, A.Usami, K. Onizuka, K.Yamada and F. Nagatsugi
    • Organizer
      XXII Round Table on Nucleosides, Nucleotides and Nucleic Acids Chemical Biology of Nucleic Acids
    • Place of Presentation
      Paris, France
    • Year and Date
      2016-07-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K14975

  • [Presentation] 核酸標的擬ロタキサン形成オリゴDNAの構造最適化2016
    • Author(s)
      宮下卓也、鬼塚和光、永次　史
    • Organizer
      日本化学会第９６春季年会
    • Place of Presentation
      同志社大学、京都
    • Year and Date
      2016-03-24
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] 標的核酸に対して自発的に擬ロタキサン構造を形成する人工核酸の開発2016
    • Author(s)
      鬼塚　和光、宮下　卓也、永次　史
    • Organizer
      第１０回バイオ関連化学シンポジウム
    • Place of Presentation
      石川県立音楽堂もてなしドーム（石川県金沢市）
    • Year and Date
      2016-09-07
    • Data Source
      KAKENHI-PROJECT-15K14975

  • [Presentation] 核酸結合性蛋白質を標的とした新規架橋反応性核酸誘導体の合成2016
    • Author(s)
      小平健太、石山 翔午、山田 研、永次 史
    • Organizer
      日本化学会第９６春季年会
    • Place of Presentation
      同志社大学、京都
    • Year and Date
      2016-03-24
    • Data Source
      KAKENHI-PROJECT-15K14975

  • [Presentation] Synthesis of a new cross-linkable nucleic acid derivative targeting nucleic acid binding protein2016
    • Author(s)
      K. Odaira, S. Ishiyama, K. Yamada, F. Nagatsugi
    • Organizer
      Tohoku University Campus Asia Program Summer School
    • Place of Presentation
      Tohoku Univ. Sendai, Japan
    • Year and Date
      2016-08-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] 遺伝子の化学的マニュピュレーションに向けた新規技術の開発2015
    • Author(s)
      永次　史
    • Organizer
      金沢大学薬学シンポジウム2014
    • Place of Presentation
      金沢大学
    • Year and Date
      2015-01-25
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-26102710

  • [Presentation] Development of the crosslinking reactions to RNA for application in cells2015
    • Author(s)
      Fumi Nagatsugi
    • Organizer
      Pharmaceutical Science Symposium
    • Place of Presentation
      Sakura Hall, Sendai, Japan
    • Year and Date
      2015-10-16
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] The effect of intra-strand cross-link formation on the stability of DNA i-motif2015
    • Author(s)
      Kenji Kikuta, Piao Haishun, John Brazir, Kazumitsu Onizuka, Fumi Nagatsugi, Yosuke Taniguchi, Shigeki Sasaki,
    • Organizer
      The 42th International Symposium on Nucleic Acids Chemistry
    • Place of Presentation
      Egret Himeji, Himeji　Japan
    • Year and Date
      2015-09-23
    • Data Source
      KAKENHI-PUBLICLY-26102710

  • [Presentation] The effect of intra-strand cross-link formation on the stability of DNA i-motif2015
    • Author(s)
      Kenji Kikuta, Piao Haishun, John Brazir, Kazumitsu Onizuka, Fumi Nagatsugi, Yosuke Taniguchi, Shigeki Sasaki
    • Organizer
      The 42th International Symposium on Nucleic Acids Chemistry
    • Place of Presentation
      Egret Himeji, Himeji　Japan
    • Year and Date
      2015-09-23
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] 遺伝子の発現を効率よく制御可能な架橋反応性ペプチド核酸(PNA)の開発2015
    • Author(s)
      秋澤　拓也、永次　史
    • Organizer
      日本ケミカルバイオロジー学会　第11回年会
    • Place of Presentation
      東北大学　川内萩ホール
    • Year and Date
      2015-06-10
    • Data Source
      KAKENHI-PUBLICLY-26102710

  • [Presentation] Pseudorotaxane formation via slipping process targeting on nucleic acids2015
    • Author(s)
      Kazumitsu Onizuka, Takuya Miyashita , Fumi Nagatsugi
    • Organizer
      The 42th International Symposium on Nucleic Acids Chemistry
    • Place of Presentation
      Egret Himeji, Himeji　Japan
    • Year and Date
      2015-09-23
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] 遺伝子の発現を効率よく制御可能な架橋反応性ペプチド核酸(PNA)の開発2015
    • Author(s)
      秋澤　拓也、永次　史
    • Organizer
      日本ケミカルバイオロジー学会　第11回年会
    • Place of Presentation
      東北大学　川内萩ホール
    • Year and Date
      2015-06-10
    • Data Source
      KAKENHI-PROJECT-15K14975

  • [Presentation] Development of small molecular probes for selective alkylation of the higher-order structure of nucleic acidsDevelopment of small molecular probes for selective alkylation of the higher-order structure of nucleic acids2015
    • Author(s)
      Yoshihiro Sasaki, Norihiro Sato, Genichiro Tsuji, Ken Yamada, Fumi Nagatsugi,
    • Organizer
      Tohoku University Campus Asia Program Summer School
    • Place of Presentation
      Sendai, Japan
    • Year and Date
      2015-08-27
    • Data Source
      KAKENHI-PUBLICLY-26102710

  • [Presentation] 生化学ツールのための架橋形成した天然擬似２本鎖RNAの合成2015
    • Author(s)
      鬼塚和光、Hazemi Madoka Eurika、永次　史
    • Organizer
      第9回バイオ関連化学シンポジウム
    • Place of Presentation
      熊本大学工学部、熊本
    • Year and Date
      2015-09-10
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] Development of the crosslinking reactions to RNA for application in cells2015
    • Author(s)
      Fumi Nagatsugi
    • Organizer
      Pharmaceutical Science Symposium
    • Place of Presentation
      Sakura hall, Sendai, Japan
    • Year and Date
      2015-10-16
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] 遺伝子の発現を効率よく制御可能な架橋反応性ペプチド核酸(PNA)の開発2015
    • Author(s)
      秋澤　拓也、永次　史、
    • Organizer
      日本ケミカルバイオロジー学会　第11回年会
    • Place of Presentation
      東北大学川内萩ホール、仙台
    • Year and Date
      2015-06-10
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] 核酸結合性タンパク質との架橋反応を目指したビニルトリアジン誘導体の合成2015
    • Author(s)
      小平健太、石山翔午、山田研、 鬼塚和光、永次史
    • Organizer
      第４回CSJ化学フェスタ2015
    • Place of Presentation
      タワーホール船堀、東京
    • Year and Date
      2015-10-14
    • Data Source
      KAKENHI-PROJECT-15K14975

  • [Presentation] 架橋反応性塩基を持つ擬相補的PNAの合成と２本鎖DNAに対する反応性評価2015
    • Author(s)
      永次　史，秋澤拓也
    • Organizer
      第１回日本核酸医薬学会年会
    • Place of Presentation
      京都テルサ、京都
    • Year and Date
      2015-11-30
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] Development of the selective crosslinking reactions to 8-oxoguanine2015
    • Author(s)
      Fumi Nagatsugi, Shuhei Kusano, Shogo Ishiyama, Sik Lok Lam, Tsukasa Mashima, Masato Katahira, Fumi Nagatsugi
    • Organizer
      The 42th International Symposium on Nucleic Acids Chemistry
    • Place of Presentation
      Egret Himeji, Himeji　Japan
    • Year and Date
      2015-09-23
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] Development of the Effective Chemical Strategy for Regulation of Gene Expression.2015
    • Author(s)
      Nagatsugi F., Hagihara S., Kusano S
    • Organizer
      Pharmaceutical Science Symposium 2015
    • Place of Presentation
      Sakura hall, Sendai, Japan
    • Year and Date
      2015-10-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] 架橋反応性ペプチド核酸（PNA）を用いた遺伝子発現制御法の開発2015
    • Author(s)
      秋澤　拓也、永次　史
    • Organizer
      第２６回万有シンポジウム
    • Place of Presentation
      仙台国際センター、仙台市
    • Year and Date
      2015-06-10
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] 核酸結合性タンパク質との架橋反応を目指したビニルトリアジン誘導体の合成2015
    • Author(s)
      小平健太、石山翔午、山田研、 鬼塚和光、永次史、2015/10/14-16
    • Organizer
      第４回CSJ化学フェスタ2015
    • Place of Presentation
      タワーホール船堀、東京
    • Year and Date
      2015-10-14
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] Development of the interlocked structure formation method targeted RNA2015
    • Author(s)
      Takuya Amemiya, Kazumitsu Onizuka, Fumi Nagatsugi
    • Organizer
      Tohoku University Campus Asia Program Summer School
    • Place of Presentation
      Tohoku University, Sendai, Japan
    • Year and Date
      2015-08-28
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] 核酸を標的とした擬ロタキサン形成オリゴDNAの構造最適化2015
    • Author(s)
      宮下　卓也、鬼塚和光、永次　史、
    • Organizer
      第9回バイオ関連化学シンポジウム
    • Place of Presentation
      熊本大学工学部、熊本
    • Year and Date
      2015-09-10
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] Development of the crosslinking reactions to RNA for application in cells2015
    • Author(s)
      Fumi Nagatsugi
    • Organizer
      Pharmaceutical Science Symposium 2015
    • Place of Presentation
      Sakura Hall, Sendai, Japan
    • Year and Date
      2015-10-16
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K14975

  • [Presentation] 核酸結合性蛋白質との反応を目指したビニルトリアジンを有する核酸誘導体の開発2015
    • Author(s)
      山田 研、石山 翔午、鬼塚 和光、永次 史
    • Organizer
      第9回バイオ関連化学シンポジウム
    • Place of Presentation
      熊本大学工学部、熊本
    • Year and Date
      2015-09-10
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] 架橋反応性塩基を持つ擬相補的PNAの合成と２本鎖DNAに対する反応性評価2015
    • Author(s)
      永次　史，秋澤拓也
    • Organizer
      第１回日本核酸医薬学会年会
    • Place of Presentation
      京都テルサ、京都
    • Year and Date
      2015-11-30
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] 効率的遺伝子発現制御を目指した選択的化学反応の開発2015
    • Author(s)
      永次　史
    • Organizer
      第３２回有機合成セミナ
    • Place of Presentation
      ニューウェルシティ湯河原　湯河原, 神奈川県
    • Year and Date
      2015-09-15
    • Invited
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] Synthesis of vinyltriazine derivatives aiming at alkylation to U&#8210;U mismatch structure in RNA2015
    • Author(s)
      Tomohito Kobayashi, Kazumitsu Onizuka, Fumi Nagatsugi
    • Organizer
      Tohoku University Campus Asia Program Summer School
    • Place of Presentation
      Tohoku university, Sendai, Japan
    • Year and Date
      2015-08-28
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] 効率的遺伝子発現制御を目指した選択的化学反応の開発2015
    • Author(s)
      永次　史
    • Organizer
      第３２回有機合成セミナー
    • Place of Presentation
      ニューウェルシテ湯河原　熱海市
    • Year and Date
      2015-09-15
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-26102710

  • [Presentation] 核酸結合性蛋白質との架橋反応を目指したビニルトリアジン誘導体の開発2015
    • Author(s)
      山田　研、石山 翔午、鬼塚和光、永次　史
    • Organizer
      日本ケミカルバイオロジー学会　第11回年会
    • Place of Presentation
      東北大学　川内萩ホール
    • Year and Date
      2015-06-10
    • Data Source
      KAKENHI-PUBLICLY-26102710

  • [Presentation] Development of small molecular probes for selective alkylation of the higher-order structure of nucleic acid2015
    • Author(s)
      Yoshihiro Sasaki, Norihiro Sato, Genichiro Tsuji, Ken Yamada, Fumi Nagatsugi, s
    • Organizer
      Tohoku University Campus Asia Program Summer School
    • Place of Presentation
      Tohoku University, Sendai, Japan
    • Year and Date
      2015-08-28
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] 核酸を標的とした擬ロタキサン形成オリゴDNAの構造最適化2015
    • Author(s)
      宮下　卓也、鬼塚和光、永次　史
    • Organizer
      第9回バイオ関連化学シンポジウム
    • Place of Presentation
      熊本大学工学部・黒髪南キャンパス
    • Year and Date
      2015-09-10
    • Data Source
      KAKENHI-PUBLICLY-26102710

  • [Presentation] RNＡのミスマッチ構造選択的にアルキル化する分子の開発2015
    • Author(s)
      小林倫仁、鬼塚和光、永次　史2015/6/10-12
    • Organizer
      日本ケミカルバイオロジー学会　第11回年会
    • Place of Presentation
      東北大学川内萩ホール、仙台
    • Year and Date
      2015-06-10
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] 生化学ツールのための架橋形成した天然擬似２本鎖RNAの合成2015
    • Author(s)
      鬼塚和光、Hazemi Madoka Eurika、永次　史
    • Organizer
      第9回バイオ関連化学シンポジウム
    • Place of Presentation
      熊本大学工学部・黒髪南キャンパス
    • Year and Date
      2015-09-10
    • Data Source
      KAKENHI-PUBLICLY-26102710

  • [Presentation] 生化学ツールのための架橋形成した天然擬似２本鎖RNAの合成2015
    • Author(s)
      鬼塚和光、Hazemi Madoka Eurika、永次　史、
    • Organizer
      第9回バイオ関連化学シンポジウム
    • Place of Presentation
      熊本大学工学部　熊本
    • Year and Date
      2015-09-10
    • Data Source
      KAKENHI-PROJECT-15K14975

  • [Presentation] Development of the selective crosslinking reactions to 8-oxoguanine2015
    • Author(s)
      Fumi Nagatsugi, Shuhei Kusano, Shogo Ishiyama, Sik Lok Lam, Tsukasa Mashima, Masato Katahira, Fumi Nagatsugi
    • Organizer
      The 42th International Symposium on Nucleic Acids Chemistry
    • Place of Presentation
      Egret Himeji, Himeji　Japan
    • Year and Date
      2015-09-23
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] Development of pseudorotaxane formation methods targeting on nucleic acids2015
    • Author(s)
      Kazumitsu Onizuka, Yoshihiro Ito, Hiroshi Abe, Fumi Nagatsugi
    • Organizer
      Pacifichem 2015
    • Place of Presentation
      Hawaii, USA.
    • Year and Date
      2015-12-15
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] 架橋反応性ペプチド核酸（PNA）を用いた遺伝子発現制御法の開発2015
    • Author(s)
      秋澤　拓也、永次　史
    • Organizer
      第２６回万有シンポジウム
    • Place of Presentation
      仙台国際センター、仙台市
    • Year and Date
      2015-06-06
    • Data Source
      KAKENHI-PUBLICLY-26102710

  • [Presentation] Pseudorotaxane formation via slipping process targeting on nucleic acids,2015
    • Author(s)
      Kazumitsu Onizuka, Takuya Miyashita , Fumi Nagatsugi
    • Organizer
      The 42th International Symposium on Nucleic Acids Chemistry
    • Place of Presentation
      Egret Himeji, Himeji　Japan
    • Year and Date
      2015-09-23
    • Data Source
      KAKENHI-PUBLICLY-26102710

  • [Presentation] 鎖内クロスリンク形成によるi-motifの安定化2015
    • Author(s)
      菊田健司、朴　海順、John Brazier、鬼塚和光、永次　史、谷口陽祐、佐々木茂貴
    • Organizer
      第9回バイオ関連化学シンポジウム
    • Place of Presentation
      熊本大学工学部・黒髪南キャンパス
    • Year and Date
      2015-09-10
    • Data Source
      KAKENHI-PUBLICLY-26102710

  • [Presentation] 効率的遺伝子発現制御を目指した選択的化学反応の開発2015
    • Author(s)
      永次　史
    • Organizer
      第３２回有機合成セミナ
    • Place of Presentation
      ウェルシティ湯河原、湯河原、神奈川県
    • Year and Date
      2015-09-15
    • Invited
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] Synthesis and Evaluation of the Reactivity of 7-Deaza-6-vinylguanosine Derivatives,2015
    • Author(s)
      Yusuke Abe, Ken Yamada, Yuta Ida, and Fumi Nagatsugi
    • Organizer
      Tohoku University Campus Asia Program Summer School
    • Place of Presentation
      Sendai, Japan
    • Year and Date
      2015-08-28
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K14975

  • [Presentation] 核酸結合性蛋白質との架橋反応を目指したビニルトリアジン誘導体の開発2015
    • Author(s)
      山田　研、石山 翔午、鬼塚和光、永次　史
    • Organizer
      日本ケミカルバイオロジー学会　第11回年会
    • Place of Presentation
      東北大学川内萩ホール、仙台
    • Year and Date
      2015-06-10
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] 核酸結合性蛋白質との反応を目指したビニルトリアジンを有する核酸誘導体の開発2015
    • Author(s)
      山田 研、石山 翔午、鬼塚 和光、永次 史
    • Organizer
      第9回バイオ関連化学シンポジウム
    • Place of Presentation
      熊本大学工学部　熊本
    • Year and Date
      2015-09-10
    • Data Source
      KAKENHI-PROJECT-15K14975

  • [Presentation] 遺伝子の化学的マニュピュレーションに向けた新規技術の開発2015
    • Author(s)
      永次　史
    • Organizer
      金沢大学薬学シンポジウム2014
    • Place of Presentation
      金沢大学
    • Year and Date
      2015-01-25
    • Invited
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] RNAを高次構造選択的に化学修飾する小分子プローブの開発2015
    • Author(s)
      宇佐美　彬、佐藤憲大、鬼塚和光、永次　史、
    • Organizer
      第9回バイオ関連化学シンポジウム
    • Place of Presentation
      熊本大学工学部　熊本
    • Year and Date
      2015-09-10
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] 効率的遺伝子発現制御を目指した選択的化学反応の開発2015
    • Author(s)
      永次　史
    • Organizer
      第３２回有機合成セミナー
    • Place of Presentation
      ウェルシティー湯河原、湯河原、神奈川県
    • Year and Date
      2015-09-15
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K14975

  • [Presentation] Development of the interlocked structure formation method targeted RNA2015
    • Author(s)
      Takuya Amemiya, Kazumitsu Onizuka, Fumi Nagatsugi,
    • Organizer
      Tohoku University Campus Asia Program Summer School
    • Place of Presentation
      Sendai, Japan
    • Year and Date
      2015-08-27
    • Data Source
      KAKENHI-PUBLICLY-26102710

  • [Presentation] RNAを標的とした擬ロタキサン形成オリゴDNAの構造最適化2015
    • Author(s)
      宮下 卓也, 鬼塚 和光, 永次 史
    • Organizer
      第15回多元物質科学研究所研究発表会
    • Place of Presentation
      東北大学片平キャンパス・さくらホール、仙台
    • Year and Date
      2015-12-22
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] DNA高次構造選択的にアルキル化する小分子の開発2015
    • Author(s)
      佐々木欣宏、佐藤憲大、辻厳一郎、山田　研、永次　史、佐藤 憲大、辻 厳一郎、茂木 琢真、鬼塚 和光、永次 史、、
    • Organizer
      第9回バイオ関連化学シンポジウム
    • Place of Presentation
      熊本大学工学部、熊本
    • Year and Date
      2015-09-10
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] Synthesis of vinyltriazine derivatives aiming at alkylation to U-U mismatch structure in RNA2015
    • Author(s)
      Tomohito Kobayashi, Kazumitsu Onizuka, Fumi Nagatsugi
    • Organizer
      Tohoku University Campus Asia Program Summer School
    • Place of Presentation
      Sendai, Japan
    • Year and Date
      2015-08-27
    • Data Source
      KAKENHI-PUBLICLY-26102710

  • [Presentation] Development of the selective crosslinking reactions to 8-oxoguanine2015
    • Author(s)
      Fumi Nagatsugi, Shuhei Kusano, Shogo Ishiyama, Sik Lok Lam, Tsukasa Mashima, Masato Katahira, Fumi Nagatsugi
    • Organizer
      The 42th International Symposium on Nucleic Acids Chemistry
    • Place of Presentation
      Egret Himeji, Himeji　Japan
    • Year and Date
      2015-09-23
    • Data Source
      KAKENHI-PUBLICLY-26102710

  • [Presentation] 核酸結合性蛋白質との架橋反応を目指したビニルトリアジン誘導体の開発2015
    • Author(s)
      山田　研、石山 翔午、鬼塚和光、永次　史
    • Organizer
      日本ケミカルバイオロジー学会　第11回年会
    • Place of Presentation
      東北大学　川内萩ホール
    • Year and Date
      2015-06-10
    • Data Source
      KAKENHI-PROJECT-15K14975

  • [Presentation] 核酸結合性蛋白質との反応を目指したビニルトリアジンを有する核酸誘導体の開発2015
    • Author(s)
      山田 研、石山 翔午、鬼塚 和光、永次 史
    • Organizer
      第9回バイオ関連化学シンポジウム
    • Place of Presentation
      熊本大学工学部　熊本
    • Year and Date
      2015-09-10
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] Synthesis and Evaluation of the Reactivity of 7-Deaza-6-vinylguanosine Derivatives2015
    • Author(s)
      Yusuke Abe, Ken Yamada, Yuta Ida, and Fumi Nagatsugi
    • Organizer
      Tohoku University Campus Asia Program Summer School
    • Place of Presentation
      Sendai, Japan
    • Year and Date
      2015-08-27
    • Data Source
      KAKENHI-PUBLICLY-26102710

  • [Presentation] DNA高次構造選択的にアルキル化する小分子の開発2015
    • Author(s)
      佐々木欣宏、佐藤憲大、辻厳一郎、山田　研、永次　史、佐藤 憲大、辻 厳一郎、茂木 琢真、鬼塚 和光、永次 史、
    • Organizer
      第9回バイオ関連化学シンポジウム
    • Place of Presentation
      熊本大学工学部　熊本
    • Year and Date
      2015-09-10
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] RNAを高次構造選択的に化学修飾する小分子プローブの開発2015
    • Author(s)
      宇佐美　彬、佐藤憲大、鬼塚和光、永次　史、
    • Organizer
      第9回バイオ関連化学シンポジウム
    • Place of Presentation
      熊本大学工学部、熊本
    • Year and Date
      2015-09-10
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] Synthesis of vinyltriazine derivatives aiming at alkylation to U&#8210;U mismatch structure in RNA2015
    • Author(s)
      Tomohito Kobayashi, Kazumitsu Onizuka, Fumi Nagatsugi
    • Organizer
      Tohoku University Campus Asia Program Summer School
    • Place of Presentation
      Tohoku University, Sendai, Japan
    • Year and Date
      2015-08-28
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] RNAを高次構造選択的に化学修飾する小分子プローブの開発2015
    • Author(s)
      宇佐美　彬、佐藤憲大、鬼塚和光、永次　史
    • Organizer
      第9回バイオ関連化学シンポジウム
    • Place of Presentation
      熊本大学工学部・黒髪南キャンパス
    • Year and Date
      2015-09-10
    • Data Source
      KAKENHI-PUBLICLY-26102710

  • [Presentation] 核酸高次構造における選択的アルキル化反応の開発2015
    • Author(s)
      永次　史、佐藤憲大、佐々木欣宏、辻厳一郎、小林倫仁、山田　研、鬼塚和光
    • Organizer
      日本ケミカルバイオロジー学会　第11回年会
    • Place of Presentation
      東北大学　川内萩ホール
    • Year and Date
      2015-06-10
    • Data Source
      KAKENHI-PUBLICLY-26102710

  • [Presentation] 核酸結合性タンパク質との架橋反応を目指したビニルトリアジン誘導体の合成2015
    • Author(s)
      小平健太、石山翔午、山田研、 鬼塚和光、永次史
    • Organizer
      第４回CSJ化学フェスタ2015
    • Place of Presentation
      タワーホール船堀、東京
    • Year and Date
      2015-10-14
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] 架橋反応性ペプチド核酸（PNA）を用いた遺伝子発現制御法の開発2015
    • Author(s)
      秋澤　拓也、永次　史
    • Organizer
      第２６回万有シンポジウム
    • Place of Presentation
      仙台国際センター、仙台市
    • Year and Date
      2015-06-06
    • Data Source
      KAKENHI-PROJECT-15K14975

  • [Presentation] DNA高次構造選択的にアルキル化する小分子の開発2015
    • Author(s)
      佐々木欣宏、佐藤憲大、辻厳一郎、山田　研、永次　史、佐藤 憲大、辻 厳一郎、茂木 琢真、鬼塚 和光、永次 史、
    • Organizer
      第9回バイオ関連化学シンポジウム
    • Place of Presentation
      熊本大学工学部・黒髪南キャンパス
    • Year and Date
      2015-09-10
    • Data Source
      KAKENHI-PUBLICLY-26102710

  • [Presentation] Synthesis and Evaluation of the Reactivity of 7-Deaza-6-vinylguanosine Derivatives, Tohoku University Campus Asia Program Summer Schoo2015
    • Author(s)
      Yusuke Abe, Ken Yamada, Yuta Ida, and Fumi Nagatsugi
    • Organizer
      Tohoku University Campus Asia Program Summer School
    • Place of Presentation
      Tohoku university, Sendai, Japan
    • Year and Date
      2015-08-28
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] Development of small molecular probes for selective alkylation of the higher-order structure of nucleic acids2015
    • Author(s)
      Yoshihiro Sasaki, Norihiro Sato, Genichiro Tsuji, Ken Yamada, Fumi Nagatsugi,
    • Organizer
      Tohoku University Campus Asia Program Summer School
    • Place of Presentation
      Tohoku university,Sendai, Japan
    • Year and Date
      2015-08-28
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] 架橋反応性塩基を持つ擬相補的PNAの合成と２本鎖DNAに対する反応性評価2015
    • Author(s)
      永次　史，秋澤拓也
    • Organizer
      第１回日本核酸医薬学会年会
    • Place of Presentation
      京都テルサ、京都
    • Year and Date
      2015-11-30
    • Data Source
      KAKENHI-PROJECT-15K14975

  • [Presentation] Development of the Effective Chemical Strategy for Regulation of Gene Expression2015
    • Author(s)
      Nagatsugi F., Hagihara S., Kusano S.
    • Organizer
      Pharmaceutical Science Symposium 2015
    • Place of Presentation
      Sakura Hall, Sendai, Japan
    • Year and Date
      2015-10-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K14975

  • [Presentation] RNＡのミスマッチ構造選択的にアルキル化する分子の開発2015
    • Author(s)
      小林倫仁、鬼塚和光、永次　史
    • Organizer
      日本ケミカルバイオロジー学会　第11回年会
    • Place of Presentation
      東北大学　川内萩ホール
    • Year and Date
      2015-06-10
    • Data Source
      KAKENHI-PUBLICLY-26102710

  • [Presentation] Development of the selective crosslinking reactions to 8-oxoguanine2015
    • Author(s)
      Fumi Nagatsugi, Shuhei Kusano, Shogo Ishiyama, Sik Lok Lam, Tsukasa Mashima, Masato Katahira, Fumi Nagatsugi
    • Organizer
      The 42th International Symposium on Nucleic Acids Chemistry
    • Place of Presentation
      Egret Himeji, Himeji, Japan
    • Year and Date
      2015-09-23
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K14975

  • [Presentation] Synthesis and Evaluation of the Reactivity of 7-Deaza-6-vinylguanosine Derivatives2015
    • Author(s)
      Yusuke Abe, Ken Yamada, Yuta Ida, and Fumi Nagatsugi
    • Organizer
      Tohoku University Campus Asia Program Summer School
    • Place of Presentation
      Tohoku University,Sendai, Japan
    • Year and Date
      2015-08-28
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] 核酸高次構造における選択的アルキル化反応の開発2015
    • Author(s)
      永次　史、佐藤憲大、佐々木欣宏、辻厳一郎、小林倫仁、山田　研、鬼塚和光、
    • Organizer
      日本ケミカルバイオロジー学会　第11回年会
    • Place of Presentation
      東北大学川内萩ホール、仙台
    • Year and Date
      2015-06-10
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] 鎖内クロスリンク形成によるi-motifの安定化2015
    • Author(s)
      菊田健司、朴　海順、John Brazier、鬼塚和光、永次　史、谷口陽祐、佐々木茂貴、
    • Organizer
      第9回バイオ関連化学シンポジウム
    • Place of Presentation
      熊本大学工学部、熊本
    • Year and Date
      2015-09-10
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] 遺伝子を標的とした新規機能性低分子プローブの開発　天然物ケミカルバイオロジー:分子標的と活性制御2015
    • Author(s)
      永次　史、茂木　琢磨、草野修平、佐藤憲大
    • Organizer
      第６回領域公開シンポジウム
    • Place of Presentation
      東北大学
    • Year and Date
      2015-06-08
    • Data Source
      KAKENHI-PUBLICLY-26102710

  • [Presentation] Development of the strategy for the selective chemical modification in a hydrophobic site in DNA or RNA2015
    • Author(s)
      Norihiro Sato, Tomohito Kobayashi, Yoshihiro Sasaki, Kazumitsu Onizuka, Ken Yamada, Fumi Nagatsugi
    • Organizer
      Pacifichem 2015
    • Place of Presentation
      Hawaii, USA.
    • Year and Date
      2015-12-15
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05838

  • [Presentation] 細胞内遺伝子発現制御を目指した酸化応答型架橋反応性核酸の開発2014
    • Author(s)
      春山拓哉・草野修平・永次　史
    • Organizer
      日本化学会第94春季年会
    • Place of Presentation
      名古屋大学
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] 疎水空間を有する2本鎖DNAに対する化学修飾法の開発2014
    • Author(s)
      佐藤　憲大・辻　厳一郎・茂木　琢真・永次　史
    • Organizer
      日本化学会第94春季年会
    • Place of Presentation
      名古屋大学
    • Data Source
      KAKENHI-PUBLICLY-24102508

  • [Presentation] Development of the Strategy for the Selective Chemical Modification in Hydrophobic Pockets2014
    • Author(s)
      F. Nagatsugi, G. Tsuji, S.Norihiro
    • Organizer
      Asian Chemical Biology Initiative 2014
    • Place of Presentation
      Manila Meeting Manila Hotel
    • Invited
    • Data Source
      KAKENHI-PROJECT-21229002

  • [Presentation] 細胞内遺伝子発現制御を目指した酸化応答型架橋反応性核酸の開発2014
    • Author(s)
      春山拓哉・草野修平・永次　史
    • Organizer
      日本化学会第94春季年会
    • Place of Presentation
      名古屋大学
    • Data Source
      KAKENHI-PUBLICLY-24102508

  • [Presentation] 架橋反応性核酸塩基を導入したペプチド核酸の合成と評価2014
    • Author(s)
      秋澤　拓也、石澤　悠樹、永次　史
    • Organizer
      日本化学会第94春季年会
    • Place of Presentation
      名古屋大学
    • Data Source
      KAKENHI-PROJECT-21229002

  • [Presentation] 疎水空間を有する2本鎖DNAに対する化学修飾法の開発2014
    • Author(s)
      佐藤　憲大・辻　厳一郎・茂木　琢真・永次　史
    • Organizer
      日本化学会第94春季年会
    • Place of Presentation
      名古屋大学
    • Data Source
      KAKENHI-PROJECT-21229002

  • [Presentation] 細胞内遺伝子発現制御を目指した酸化応答型架橋反応性核酸の開発2014
    • Author(s)
      春山拓哉・草野修平・永次　史
    • Organizer
      日本化学会第94春季年会
    • Place of Presentation
      名古屋大学
    • Data Source
      KAKENHI-PROJECT-21229002

  • [Presentation] グアニン類縁体に対する架橋形成ピリミジン誘導体の反応性2014
    • Author(s)
      石山　翔午、草野　修平、永次　史
    • Organizer
      日本化学会第94春季年会
    • Place of Presentation
      名古屋大学
    • Data Source
      KAKENHI-PROJECT-21229002

  • [Presentation] 2本鎖DNAの塩基欠損部位に対する化学修飾法の開発2014
    • Author(s)
      佐藤憲大、辻厳一郎、茂木琢真、鬼塚和光、永次 史
    • Organizer
      第２５回万有シンポミニシンポジウム
    • Place of Presentation
      東北大学、仙台
    • Year and Date
      2014-06-13
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] 核酸を標的にした擬ロタキサン形成法の開発2014
    • Author(s)
      鬼塚和光、伊藤嘉浩、阿部　洋、永次 史
    • Organizer
      第14回多元物質科学研究所研究発表会
    • Place of Presentation
      東北大学片平キャンパス・さくらホール、仙台
    • Year and Date
      2014-12-05
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] 疎水空間を有する2本鎖DNAに対する化学修飾法の開発2014
    • Author(s)
      佐藤　憲大・辻　厳一郎・茂木　琢真・永次　史
    • Organizer
      日本化学会第94春季年会
    • Place of Presentation
      名古屋大学
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] グアニン類縁体に対する架橋形成ピリミジン誘導体の反応性2014
    • Author(s)
      石山　翔午、草野　修平、永次　史
    • Organizer
      日本化学会第94春季年会
    • Place of Presentation
      名古屋大学
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] Development of the Strategy for the Selective Chemical Modification in Hydrophobic Pockets2014
    • Author(s)
      F. Nagatsugi, G. Tsuji, S.Norihiro
    • Organizer
      Asian Chemical Biology Initiative 2014 Manila Meeting
    • Place of Presentation
      Manila Hotel、Phylipin
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-24102508

  • [Presentation] グアニン類縁体に対する架橋反応性核酸の反応及び構造解析2014
    • Author(s)
      .石山　翔午、草野　修平、永次　史
    • Organizer
      第２５回万有シンポジウム
    • Place of Presentation
      仙台国際センター、仙台市
    • Year and Date
      2014-06-14
    • Data Source
      KAKENHI-PUBLICLY-26102710

  • [Presentation] グアニン類縁体に対する架橋形成ピリミジン誘導体の反応性2014
    • Author(s)
      石山　翔午、草野　修平、永次　史
    • Organizer
      日本化学会第94春季年会
    • Place of Presentation
      名古屋大学
    • Data Source
      KAKENHI-PUBLICLY-24102508

  • [Presentation] 架橋反応性核酸塩基を導入したペプチド核酸の合成と評価2014
    • Author(s)
      秋澤　拓也、石澤　悠樹、永次　史
    • Organizer
      日本化学会第94春季年会
    • Place of Presentation
      名古屋大学
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] 化学反応性オリゴDNAを用いたRNA標的擬ロタキサン形成法の開発2014
    • Author(s)
      鬼塚和光、伊藤嘉浩、阿部　洋、永次 史
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      熊本大学
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] Inhibition of the miRNA function by using of Crosslink Reaction2014
    • Author(s)
      Fumi Nagatsugi
    • Organizer
      The 1st International Symposium of Chemistry and Biology of RNA Interference
    • Place of Presentation
      Kitakyushu International Conference Center, Kitakyushu, Japan
    • Year and Date
      2014-11-04
    • Invited
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] Development of the Strategy for the Selective Chemical Modification in Hydrophobic Pockets2014
    • Author(s)
      F. Nagatsugi, G. Tsuji, S.Norihiro
    • Organizer
      Asian Chemical Biology Initiative 2014 Manila Meeting
    • Place of Presentation
      Philipin, Manila hotel
    • Invited
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] 2本鎖DNAの塩基欠損部位に対する化学修飾法の開発2014
    • Author(s)
      佐藤憲大、辻厳一郎、茂木琢真、鬼塚和光、永次史
    • Organizer
      第２５回万有シンポミニシンポジウム
    • Place of Presentation
      東北大学、仙台
    • Year and Date
      2014-06-13
    • Data Source
      KAKENHI-PUBLICLY-26102710

  • [Presentation] 化学反応性オリゴDNAを用いたRNA標的擬ロタキサン形成法の開発2014
    • Author(s)
      鬼塚和光、伊藤嘉浩、阿部　洋、永次 史
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      熊本大学
    • Data Source
      KAKENHI-PUBLICLY-24102508

  • [Presentation] 架橋反応性核酸塩基を導入したペプチド核酸の合成と評価2014
    • Author(s)
      秋澤　拓也、石澤　悠樹、永次　史
    • Organizer
      日本化学会第94春季年会
    • Place of Presentation
      名古屋大学
    • Data Source
      KAKENHI-PUBLICLY-24102508

  • [Presentation] 化学反応性オリゴDNAを用いたRNA標的擬ロタキサン形成法の開発2014
    • Author(s)
      鬼塚和光、伊藤嘉浩、阿部　洋、永次 史
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      熊本大学
    • Data Source
      KAKENHI-PROJECT-21229002

  • [Presentation] 架橋反応性を有したペプチド核酸（PNA）の合成と機能性評価2014
    • Author(s)
      秋澤拓也、児玉栄一、永次 史
    • Organizer
      第14回多元物質科学研究所研究発表会
    • Place of Presentation
      東北大学片平キャンパス・さくらホール、仙台
    • Year and Date
      2014-12-05
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] Inhibition of the miRNA Function by Using of Crosslink Reactions2014
    • Author(s)
      Fumi Nagatsugi
    • Organizer
      The 1st International Symposium of Chemistry and Biology of RNA Interference
    • Place of Presentation
      Kitakyushu International Conference Center, Kitakyushu, Japan
    • Year and Date
      2014-11-04
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-26102710

  • [Presentation] グアニン類縁体に対する架橋反応性核酸の反応及び構造解析2014
    • Author(s)
      石山　翔午、草野　修平、永次　史
    • Organizer
      第２５回万有シンポジウム
    • Place of Presentation
      仙台国際センター、仙台市
    • Year and Date
      2014-06-14
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] 細胞内における遺伝子発現制御を目指した選択的架橋反応性核酸の開発2013
    • Author(s)
      3. 永次　史
    • Organizer
      日本薬学会東海支部特別講演会
    • Place of Presentation
      岐阜薬大　岐阜
    • Invited
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] 細胞内における遺伝子発現制御を目指した選択的架橋反応性核酸の開発2013
    • Author(s)
      永次　史
    • Organizer
      日本薬学会東海支部特別講演会
    • Place of Presentation
      岐阜薬大　岐阜
    • Invited
    • Data Source
      KAKENHI-PROJECT-21229002

  • [Presentation] Development of the Strategy for the Selective Chemical Modification to an Abasic Site in Duplex DNA2013
    • Author(s)
      Norihiro Sato, Takuma Moki, Shinya Hagihara, Fumi Nagatsugi
    • Organizer
      4th UK/Japan Conference in Catalytic Asymmetric Synthesis
    • Place of Presentation
      Sendai, Japan
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] 架橋反応性核酸を用いたIn Cell Chemistryへの展開(Selected Oral)2013
    • Author(s)
      永次　史、萩原伸也、草野修平、春山拓哉
    • Organizer
      第３９回反応と合成の進歩シンポジウム
    • Place of Presentation
      九州大学 医学部 百年講堂、福岡
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] 酸化反応をトリガーとする架橋反応の開発2013
    • Author(s)
      草野　修平、岩本　直生、萩原　伸也、永次　史
    • Organizer
      第７回バイオ関連化学シンポジウム
    • Place of Presentation
      名古屋大学
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] Effective Chemical Strategy for Regulation of Gene Expression using Cross-linking Reactions2013
    • Author(s)
      9. Fumi Nagatsugi, Shinya Hagihara, Shuhei Kusano, Takuya Akisawa
    • Organizer
      9th Annual Meeting of the Oligonucleotide Therapeutics Society
    • Place of Presentation
      Napoli, Italia
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] 遺伝子発現の化学的制御を目指した機能性分子の創製とその機能性評価2013
    • Author(s)
      永次　史
    • Organizer
      第３回　慶応義塾大学　戦略的研究基盤形成支援事業シンポジウム
    • Place of Presentation
      慶応義塾大学日吉キャンパス
    • Invited
    • Data Source
      KAKENHI-PROJECT-21229002

  • [Presentation] Development of the cross-link forming pyrimidine derivative2013
    • Author(s)
      Shuhei Kusano, Shogo Ishiyama, Shinya Hagihara, and Fumi Nagatsugi
    • Organizer
      International Symposium for the 70th Anniversary of the Tohoku Branch of the Chemical Society of Japan
    • Place of Presentation
      Sendai, Japan
    • Data Source
      KAKENHI-PUBLICLY-24102508

  • [Presentation] Development of the New Strategy for Selective Reactions to DNA in an Abasic site2013
    • Author(s)
      Fumi Nagatsugi
    • Organizer
      The 2nd International Symposium on Chemical Biology of Natural Products:Target ID and Regulation of Bioactivity
    • Place of Presentation
      PACIFICO YOKOHAMA, Japan
    • Data Source
      KAKENHI-PROJECT-21229002

  • [Presentation] グアニンに対して選択的に反応する架橋反応剤の開発2013
    • Author(s)
      永次　史、草野修平、萩原　伸也
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      横浜
    • Year and Date
      2013-03-28
    • Data Source
      KAKENHI-PUBLICLY-24102508

  • [Presentation] Development of the Oxidation Induced Crosslink Reaction2013
    • Author(s)
      Shuhei Kusano, Takuya Haruyama, Nao Iwamoto, Shinya Hagihara, Fumi Nagatsugi
    • Organizer
      The 40th International Symposium on Nucleic Acids Chemistry
    • Place of Presentation
      Kanagawa University, Japan
    • Data Source
      KAKENHI-PUBLICLY-24102508

  • [Presentation] 酸化反応をトリガーとする架橋反応性分子の開発2013
    • Author(s)
      草野　修平、岩本　直生、萩原　伸也、春山　拓哉、永次　史
    • Organizer
      第１回バイオ関連化学シンポジウム若手フォーラム
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-21229002

  • [Presentation] 架橋反応性核酸を用いたIn Cell Chemistryへの展開(Selected Oral)2013
    • Author(s)
      永次　史、萩原伸也、草野修平、春山拓哉
    • Organizer
      第３９回反応と合成の進歩シンポジウム
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-21229002

  • [Presentation] Development of the Oxidation Induced Crosslink Reaction2013
    • Author(s)
      Shuhei Kusano, Takuya Haruyama, Nao Iwamoto, Shinya Hagihara, Fumi Nagatsugi,
    • Organizer
      The 40th International Symposium on Nucleic Acids Chemistry
    • Place of Presentation
      Kanagawa University, Japan
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] Regulation of the Gene Expression by the Use of Reactive Oligonucleotides2013
    • Author(s)
      Fumi Nagatsugi
    • Organizer
      Technologies for Medical Diagnostic and Therapy Symposium
    • Place of Presentation
      academia sinica, Taiwan
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-24102508

  • [Presentation] グアニンおよび8-オキソグアニンに対する架橋形成ピリミジン誘導体の反応性2013
    • Author(s)
      石山　翔午，草野　修平，永次　史
    • Organizer
      第３９回反応と合成の進歩シンポジウム
    • Place of Presentation
      九州大学 医学部 百年講堂
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] Development of the molecular probes to achieve the selective chemical modification in an abasic site2013
    • Author(s)
      Norihiro Sato, Takuma Moki, Shinya Hagihara, Fumi Nagatsugi
    • Organizer
      International Symposium for the 70th Anniversary of the Tohoku Branch of the Chemical Society of Japan
    • Place of Presentation
      Sendai, Japan
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] Effective Chemical Strategy for Regulation of Gene Expression using Cross-linking Reactions2013
    • Author(s)
      Fumi Nagatsugi, Shinya Hagihara, Shuhei Kusano, Takuya Akisawa
    • Organizer
      9th Annual Meeting of the Oligonucleotide Therapeutics Society
    • Place of Presentation
      Napoli, Italia
    • Data Source
      KAKENHI-PUBLICLY-24102508

  • [Presentation] Development of the molecular probes to achieve the selective chemical modification in an abasic site2013
    • Author(s)
      Norihiro Sato, Takuma Moki, Shinya Hagihara, Fumi Nagatsugi
    • Organizer
      International Symposium for the 70th Anniversary of the Tohoku Branch of the Chemical Society of Japan
    • Place of Presentation
      Sendai, Japan
    • Data Source
      KAKENHI-PROJECT-21229002

  • [Presentation] 遺伝子を標的とした新規機能性低分子プローブの開発2013
    • Author(s)
      永次　史、茂木　琢磨、草野修平、佐藤憲大
    • Organizer
      第３回領域公開シンポジウム
    • Place of Presentation
      筑波
    • Data Source
      KAKENHI-PROJECT-21229002

  • [Presentation] 塩基欠損部位を有する２本鎖DNAに対する化学的修飾法の開発2013
    • Author(s)
      辻厳一郎、佐藤憲大、茂木琢真、永次　史
    • Organizer
      第３９回反応と合成の進歩シンポジウム
    • Place of Presentation
      九州大学 医学部 百年講堂、福岡
    • Data Source
      KAKENHI-PUBLICLY-24102508

  • [Presentation] Development of the New Strategy for Selective Reactions to DNA in an Abasic site2013
    • Author(s)
      Fumi Nagatsugi,
    • Organizer
      The 2nd International Symposium on Chemical Biology of Natural Products:Target ID and Regulation of Bioactivity
    • Place of Presentation
      PACIFICO YOKOHAMA, Japan
    • Data Source
      KAKENHI-PUBLICLY-24102508

  • [Presentation] 架橋反応性ペプチド核酸の合成と反応性検討2013
    • Author(s)
      秋澤　拓也、石澤　悠樹、永次　史
    • Organizer
      第２３回アンチセンスシンポジウム
    • Place of Presentation
      徳島（徳島大学大塚講堂）
    • Data Source
      KAKENHI-PROJECT-21229002

  • [Presentation] 塩基欠損部位を持つ2本鎖DNAにおける化学修飾法の開発2013
    • Author(s)
      佐藤憲大、茂木琢真、萩原伸也、永次　史
    • Organizer
      日本ケミカルバイオロジー学会　第8回年会
    • Place of Presentation
      東京医科歯科大学
    • Data Source
      KAKENHI-PUBLICLY-24102508

  • [Presentation] コンフォメーションを固定した新規架橋反応性核酸の開発2013
    • Author(s)
      井田裕太、萩原伸也、草野修平、永次　史
    • Organizer
      第７回バイオ関連化学シンポジウム
    • Place of Presentation
      名古屋大学
    • Data Source
      KAKENHI-PUBLICLY-24102508

  • [Presentation] 塩基欠損部位を有する２本鎖DNAに対する化学的修飾法の開発2013
    • Author(s)
      辻厳一郎、佐藤憲大、茂木琢真、永次　史
    • Organizer
      第３９回反応と合成の進歩シンポジウム
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-21229002

  • [Presentation] グアニン類縁体に対する架橋形成ピリミジン誘導体の反応性2013
    • Author(s)
      草野　修平、萩原　伸也、永次　史
    • Organizer
      日本化学会第93春季年会
    • Place of Presentation
      立命館大学、滋賀県
    • Year and Date
      2013-03-22
    • Data Source
      KAKENHI-PUBLICLY-24102508

  • [Presentation] グアニン類縁体に対する架橋形成ピリミジン誘導体の反応性2013
    • Author(s)
      草野修平、萩原伸也、永次史
    • Organizer
      日本化学会第93春季年会
    • Place of Presentation
      立命館大学、滋賀県
    • Data Source
      KAKENHI-PROJECT-23659002

  • [Presentation] 塩基欠損部位を持つ2本鎖DNAにおける化学修飾法の開発2013
    • Author(s)
      佐藤憲大、茂木琢真、萩原伸也、永次　史
    • Organizer
      日本ケミカルバイオロジー学会　第8回年会
    • Place of Presentation
      東京医科歯科大学
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] Development of the cross-link forming pyrimidine derivative2013
    • Author(s)
      Shuhei Kusano, Shogo Ishiyama, Shinya Hagihara, and Fumi Nagatsugi
    • Organizer
      International Symposium for the 70th Anniversary of the Tohoku Branch of the Chemical Society of Japan
    • Place of Presentation
      Sendai, Japan
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] 極めて高い反応性を持つ架橋反応性オリゴヌクレオチドによるテロメラーゼ阻害の検討2013
    • Author(s)
      岩本　直生、草野　修平、萩原　伸也、永次　史、
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      横浜
    • Year and Date
      2013-03-28
    • Data Source
      KAKENHI-PUBLICLY-24102508

  • [Presentation] Regulation of the Gene Expression by the Use of Reactive Oligonucleotides2013
    • Author(s)
      Fumi Nagatsugi
    • Organizer
      Technologies for Medical Diagnostic and Therapy Symposium
    • Place of Presentation
      academia sinica, Taiwan
    • Invited
    • Data Source
      KAKENHI-PROJECT-21229002

  • [Presentation] 極めて高い反応性を持つ架橋反応性オリゴヌクレオチドによるテロメラーゼ阻害の検討2013
    • Author(s)
      岩本　直生、草野　修平、萩原　伸也、永次　史、
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23659002

  • [Presentation] Development of the Effective Chemical Strategy for Regulation of Gene Expression2013
    • Author(s)
      Fumi Nagatsugi , Shinya Hagihara , Shuhei Kusano, Norihiro Sato
    • Organizer
      Gordon Conference on nucleoside, nucleotide and oligonucleotide
    • Place of Presentation
      Newport, U.S.A.
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] Development of Molecular Probe for the Selective Modification in an Abasic Site2013
    • Author(s)
      Gen-ichiro Tsuji, Norihiro Sato, Takuma Moki, Fumi Nagatsugi
    • Organizer
      The 40th International Symposium on Nucleic Acids Chemistry
    • Place of Presentation
      Kanagawa University, Japan
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] Development of the cross-link forming pyrimidine derivative2013
    • Author(s)
      Shuhei Kusano, Shogo Ishiyama, Shinya Hagihara, and Fumi Nagatsugi
    • Organizer
      International Symposium for the 70th Anniversary of the Tohoku Branch of the Chemical Society of Japan
    • Place of Presentation
      Sendai, Japan
    • Data Source
      KAKENHI-PROJECT-21229002

  • [Presentation] 酸化反応をトリガーとする架橋反応の開発2013
    • Author(s)
      草野　修平、岩本　直生、萩原　伸也、永次　史
    • Organizer
      第７回バイオ関連化学シンポジウム
    • Place of Presentation
      名古屋大学
    • Data Source
      KAKENHI-PUBLICLY-24102508

  • [Presentation] 遺伝子発現の化学的制御を目指した機能性分子の創製とその機能性評価2013
    • Author(s)
      永次　史
    • Organizer
      第３回　慶応義塾大学　戦略的研究基盤形成支援事業シンポジウム～グリーンイノベーションとライフイノベーションの架け橋～
    • Place of Presentation
      慶応義塾大学日吉キャンパス
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-24102508

  • [Presentation] Development of the Effective Chemical Strategy for Regulation of Gene Expression2013
    • Author(s)
      Fumi Nagatsugi , Shinya Hagihara , Shuhei Kusano, Norihiro Sato
    • Organizer
      5th Asian Arden Conference
    • Place of Presentation
      Nagoya, Japan
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] 架橋反応性ペプチド核酸の合成と反応性検討2013
    • Author(s)
      秋澤　拓也、石澤　悠樹、永次　史
    • Organizer
      第２３回アンチセンスシンポジウム
    • Place of Presentation
      徳島大学
    • Data Source
      KAKENHI-PUBLICLY-24102508

  • [Presentation] Development of the Chemical Strategy for Regulation of Gene Expression2013
    • Author(s)
      Fumi Nagatsugi
    • Organizer
      Asian Chemical Biology Initiative
    • Place of Presentation
      Bangkok, Thai(招待講演)
    • Data Source
      KAKENHI-PROJECT-23659002

  • [Presentation] Synthesis of Peptide Nucleic Acid (PNA) containing Cross-linking Agent2013
    • Author(s)
      Akisawa Takuya, Ishizawa Yuki, Nagatsugi Fumi
    • Organizer
      nternational Symposium for the 70th Anniversary of the Tohoku Branch of the Chemical Society of Japan
    • Place of Presentation
      Sendai, Japan
    • Data Source
      KAKENHI-PUBLICLY-24102508

  • [Presentation] 塩基欠損部位を持つ2本鎖DNAにおける部位特異的修飾方法の開発2013
    • Author(s)
      佐藤　憲大、茂木　琢真、萩原　伸也、永次　史
    • Organizer
      日本化学会第93春季年会
    • Place of Presentation
      立命館大学、滋賀県
    • Year and Date
      2013-03-22
    • Data Source
      KAKENHI-PUBLICLY-24102508

  • [Presentation] 次世代型核酸医薬を目指した架橋反応性核酸の開発2013
    • Author(s)
      永次　史
    • Organizer
      第7回次世代を担う医療薬科学シンポジウム
    • Place of Presentation
      片平さくらホール　仙台
    • Invited
    • Data Source
      KAKENHI-PROJECT-21229002

  • [Presentation] コンフォメーションを固定した新規架橋反応性核酸の開発2013
    • Author(s)
      井田裕太、萩原伸也、草野修平、永次　史
    • Organizer
      第７回バイオ関連化学シンポジウム
    • Place of Presentation
      名古屋大学
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] 化学反応性オリゴDNAを用いた擬ロタキサン形成法の開発2013
    • Author(s)
      鬼塚和光、永次 史、伊藤嘉浩、阿部　洋
    • Organizer
      第13回多元物質科学研究所研究発表会
    • Place of Presentation
      さくらホール、仙台
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] 次世代型核酸医薬を目指した架橋反応性核酸の開発2013
    • Author(s)
      3. 永次　史
    • Organizer
      第7回次世代を担う医療薬科学シンポジウム
    • Place of Presentation
      片平さくらホール　仙台
    • Invited
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] Development of Molecular Probe for the Selective Modification in an Abasic Site2013
    • Author(s)
      Gen-ichiro Tsuji, Norihiro Sato, Takuma Moki, Fumi Nagatsugi
    • Organizer
      The 40th International Symposium on Nucleic Acids Chemistry
    • Place of Presentation
      Kanagawa University, Japan
    • Data Source
      KAKENHI-PUBLICLY-24102508

  • [Presentation] Development of the Chemical Strategy for Regulation of Gene Expression2013
    • Author(s)
      Fumi Nagatsugi
    • Organizer
      2st Asian Chemical Biology Initiative
    • Place of Presentation
      Bangkok, Thai
    • Invited
    • Data Source
      KAKENHI-PROJECT-23659002

  • [Presentation] Development of the Strategy for th Selective Chemical Modification to an Abasic Site in Duplex DNA2013
    • Author(s)
      Norihiro Sato, Takuma Moki, Shinya Hagihara, Fumi Nagatsugi
    • Organizer
      4th UK/Japan Conference in Catalytic Asymmetric Synthesis
    • Place of Presentation
      Sendai
    • Data Source
      KAKENHI-PROJECT-21229002

  • [Presentation] 効率的遺伝子発現制御を目指した高い架橋形成能を持つビニルプリン誘導体の開発2013
    • Author(s)
      草野　修平、岩本　直生、萩原　伸也、永次　史
    • Organizer
      日本ケミカルバイオロジー学会　第8回年会
    • Place of Presentation
      東京医科歯科大学
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] Regulation of the Gene Expression by the Use of Reactive Oligonucleotides2013
    • Author(s)
      Fumi Nagatsugi
    • Organizer
      Technologies for Medical Diagnostic and Therapy Symposium
    • Place of Presentation
      academia sinica, Taiwan
    • Invited
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] 架橋反応性核酸を用いたRNA検出法の構築2013
    • Author(s)
      草野　修平、萩原　伸也、永次　史
    • Organizer
      第13回多元物質科学研究所研究発表会
    • Place of Presentation
      さくらホール、仙台
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] 架橋反応性核酸を用いた細胞内における遺伝子発現制御に向けた検討2013
    • Author(s)
      永次　史、萩原伸也、草野修平
    • Organizer
      第２３回アンチセンスシンポジウム
    • Place of Presentation
      徳島（徳島大学大塚講堂）
    • Data Source
      KAKENHI-PROJECT-21229002

  • [Presentation] 塩基欠損部位を持つ2本鎖DNAにおける化学修飾法の開発2013
    • Author(s)
      佐藤憲大、茂木琢真、萩原伸也、永次　史
    • Organizer
      日本ケミカルバイオロジー第８回年会
    • Place of Presentation
      東京　東京医科歯科大学
    • Data Source
      KAKENHI-PROJECT-21229002

  • [Presentation] Effective Chemical Strategy for Regulation of Gene Expression using Cross-linking Reactions2013
    • Author(s)
      Fumi Nagatsugi, Shinya Hagihara, Shuhei Kusano, Takuya Akisawa
    • Organizer
      9th Annual Meeting of the OLIGONYCLEOTIDE Therapeutics Society
    • Place of Presentation
      Napoli, Italia
    • Data Source
      KAKENHI-PROJECT-21229002

  • [Presentation] Development of the molecular probes to achieve the selective chemical modification in an abasic site2013
    • Author(s)
      Norihiro Sato, Takuma Moki, Shinya Hagihara, Fumi Nagatsugi
    • Organizer
      nternational Symposium for the 70th Anniversary of the Tohoku Branch of the Chemical Society of Japan
    • Place of Presentation
      Sendai, Japan
    • Data Source
      KAKENHI-PUBLICLY-24102508

  • [Presentation] 塩基欠損部位を持つ2本鎖DNAにおける部位特異的修飾方法の開発2013
    • Author(s)
      佐藤憲大、茂木琢真、萩原伸也、永次史
    • Organizer
      日本化学会第93春季年会
    • Place of Presentation
      立命館大学、滋賀県
    • Data Source
      KAKENHI-PROJECT-23659002

  • [Presentation] 架橋反応性ペプチド核酸の合成と反応性検討2013
    • Author(s)
      秋澤　拓也、石澤　悠樹、永次　史、
    • Organizer
      第２３回アンチセンスシンポジウム
    • Place of Presentation
      徳島大学
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] 立体配座を固定化した新規架橋性分子の開発2013
    • Author(s)
      井田　裕太、草野　修平、岩本　直生、萩原　伸也、永次　史
    • Organizer
      日本化学会第93春季年会
    • Place of Presentation
      立命館大学、滋賀県
    • Year and Date
      2013-03-22
    • Data Source
      KAKENHI-PUBLICLY-24102508

  • [Presentation] 塩基欠損部位を有する２本鎖DNAに対する化学的修飾法の開発2013
    • Author(s)
      辻厳一郎、佐藤憲大、茂木琢真、永次　史
    • Organizer
      第３９回反応と合成の進歩シンポジウム
    • Place of Presentation
      九州大学 医学部 百年講堂、福岡
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] Development of the Effective Chemical Strategy for Regulation of Gene Expression2013
    • Author(s)
      Fumi Nagatsugi , Shinya Hagihara , Shuhei Kusano, Norihiro Sato
    • Organizer
      5th Asian Arden Conference
    • Place of Presentation
      Nagoya, Japan
    • Data Source
      KAKENHI-PUBLICLY-24102508

  • [Presentation] 効率的遺伝子発現制御を目指した高い架橋形成能を持つビニルプリン誘導体の開発2013
    • Author(s)
      草野　修平、岩本　直生、萩原　伸也、永次　史、
    • Organizer
      日本ケミカルバイオロジー学会　第8回年会
    • Place of Presentation
      東京医科歯科大学
    • Data Source
      KAKENHI-PUBLICLY-24102508

  • [Presentation] Development of Molecular Probe for the Selective Modification in an Abasic Site2013
    • Author(s)
      Gen-ichiro Tsuji, Norihiro Sato, Takuma Moki, Fumi Nagatsugi
    • Organizer
      第４０回国際核酸化学シンポジウム
    • Place of Presentation
      Kanagawa University, Japan
    • Data Source
      KAKENHI-PROJECT-21229002

  • [Presentation] An efficient method for RNA modification with high sequence and base selectivity using non-natural efficient　method　for　RNA　modification　with　high　sequence　and base　selectivity　using　non-natural　functional ODN2013
    • Author(s)
      Shigeki Sasaki, Daichi Jitsuzaki, Atsushi Nishimoto, Kazumitsu Onizuka, Fumi Nagatsugi, Yosuke Taniguchi
    • Organizer
      Gordon Research Confernces
    • Place of Presentation
      Salve Regina University(USA)
    • Data Source
      KAKENHI-PROJECT-21229002

  • [Presentation] コンフォメーションを固定した新規架橋反応性核酸の開発2013
    • Author(s)
      井田裕太、萩原伸也、草野修平、永次　史
    • Organizer
      第７回バイオ関連化学シンポジウム
    • Place of Presentation
      名古屋　名古屋大学
    • Data Source
      KAKENHI-PROJECT-21229002

  • [Presentation] 細胞内における遺伝子発現制御を目指した選択的架橋反応性核酸の開発2013
    • Author(s)
      永次　史
    • Organizer
      日本薬学会東海支部特別講演会
    • Place of Presentation
      岐阜薬大　岐阜
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-24102508

  • [Presentation] 酸化反応をトリガーとする架橋反応性分子の開発2013
    • Author(s)
      草野　修平、岩本　直生、萩原　伸也、春山　拓哉、永次　史
    • Organizer
      第１回バイオ関連化学シンポジウム若手フォーラム
    • Place of Presentation
      名古屋大学
    • Data Source
      KAKENHI-PUBLICLY-24102508

  • [Presentation] 酸化反応をトリガーとする架橋反応性分子の開発2013
    • Author(s)
      10. 草野　修平、岩本　直生、萩原　伸也、春山　拓哉、永次　史
    • Organizer
      第１回バイオ関連化学シンポジウム若手フォーラム
    • Place of Presentation
      名古屋大学
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] Development of the Effective Chemical Strategy for Regulation of Gene Expression2013
    • Author(s)
      Fumi Nagatsugi, Shinya Hagihara , Shuhei Kusano, Norihiro Sato
    • Organizer
      Gordon Conference on nucleoside, nucleotide and oligonucleotide
    • Place of Presentation
      Newport, U.S.A.
    • Data Source
      KAKENHI-PROJECT-21229002

  • [Presentation] グアニンに対して選択的に反応する架橋反応剤の開発2013
    • Author(s)
      永次　史、草野修平、萩原　伸也
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23659002

  • [Presentation] Development of the Effective Chemical Strategy for Regulation of Gene Expression2013
    • Author(s)
      Fumi Nagatsugi , Shinya Hagihara , Shuhei Kusano, Norihiro Sato
    • Organizer
      Gordon Conference on nucleoside, nucleotide and oligonucleotide
    • Place of Presentation
      Newport, U.S.A
    • Data Source
      KAKENHI-PUBLICLY-24102508

  • [Presentation] 架橋反応性核酸を用いたRNA検出法の構築2013
    • Author(s)
      草野　修平、萩原　伸也、永次　史、
    • Organizer
      第13回多元物質科学研究所研究発表会
    • Place of Presentation
      北大学片平キャンパス・さくらホール、仙台
    • Data Source
      KAKENHI-PUBLICLY-24102508

  • [Presentation] Synthesis of Peptide Nucleic Acid (PNA) containing Cross-linking Agent2013
    • Author(s)
      Akisawa Takuya, Ishizawa Yuki, Nagatsugi Fumi
    • Organizer
      International Symposium for the 70th Anniversary of the Tohoku Branch of the Chemical Society of Japan
    • Place of Presentation
      Sendai, Japan
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] 立体配座を固定化した新規架橋性分子の開発2013
    • Author(s)
      井田裕太、草野修平、岩本直生、萩原伸也、永次史
    • Organizer
      日本化学会第93春季年会
    • Place of Presentation
      立命館大学、滋賀県
    • Data Source
      KAKENHI-PROJECT-23659002

  • [Presentation] 酸化反応をトリガーとする架橋反応の開発2013
    • Author(s)
      草野　修平、岩本　直生、萩原　伸也、永次　史
    • Organizer
      第７回バイオ関連化学シンポジウム
    • Place of Presentation
      名古屋　名古屋大学
    • Data Source
      KAKENHI-PROJECT-21229002

  • [Presentation] 化学反応性オリゴDNAを用いた擬ロタキサン形成法の開発2013
    • Author(s)
      鬼塚和光、永次 史、伊藤嘉浩、阿部　洋
    • Organizer
      第13回多元物質科学研究所研究発表会
    • Place of Presentation
      北大学片平キャンパス・さくらホール、仙台
    • Data Source
      KAKENHI-PUBLICLY-24102508

  • [Presentation] Design of the efficient cross-linking agent with the fixed conformation2013
    • Author(s)
      Yuta Ida, Shuhei Kusano, Shinya Hagihara, Fumi Nagatsugi
    • Organizer
      Tohoku University Campus Asia Program Summer School
    • Place of Presentation
      Sendai, Japan
    • Data Source
      KAKENHI-PUBLICLY-24102508

  • [Presentation] 効率的遺伝子発現制御を目指した高い架橋形成能を持つビニルプリン誘導体の開発2013
    • Author(s)
      草野　修平、岩本　直生、萩原　伸也、永次　史
    • Organizer
      日本ケミカルバイオロジー第８回年会
    • Place of Presentation
      東京　東京医科歯科大学
    • Data Source
      KAKENHI-PROJECT-21229002

  • [Presentation] 次世代型核酸医薬を目指した架橋反応性核酸の開発2013
    • Author(s)
      永次　史
    • Organizer
      第7回次世代を担う医療薬科学シンポジウム
    • Place of Presentation
      片平さくらホール　仙台
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-24102508

  • [Presentation] 架橋反応性核酸を用いた細胞内における遺伝子発現制御に向けた検討2013
    • Author(s)
      永次　史、萩原伸也、草野修平
    • Organizer
      第２３回アンチセンスシンポジウム
    • Place of Presentation
      徳島大学
    • Data Source
      KAKENHI-PUBLICLY-24102508

  • [Presentation] Development of the Oxidation Induced Crosslink Reaction2013
    • Author(s)
      Shuhei Kusano, Takuya Haruyama, Nao Iwamoto, Shinya Hagihara, Fumi Nagatsugi
    • Organizer
      第４０回国際核酸化学シンポジウム
    • Place of Presentation
      Kanagawa University, Japan
    • Data Source
      KAKENHI-PROJECT-21229002

  • [Presentation] Development of the Chemical Strategy for Regulation of Gene Expression2013
    • Author(s)
      Fumi Nagatsugi
    • Organizer
      2st Asian Chemical Biology Initiative
    • Place of Presentation
      Bangkok, Thai
    • Year and Date
      2013-01-25
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-24102508

  • [Presentation] グアニンおよび8-オキソグアニンに対する架橋形成ピリミジン誘導体の反応性2013
    • Author(s)
      石山　翔午，草野　修平，永次　史
    • Organizer
      第３９回反応と合成の進歩シンポジウム
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-21229002

  • [Presentation] 架橋反応性核酸を用いた細胞内における遺伝子発現制御に向けた検討2013
    • Author(s)
      永次　史、萩原伸也、草野修平
    • Organizer
      第２３回アンチセンスシンポジウム
    • Place of Presentation
      徳島大学
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] 架橋性オリゴ核酸を用いた細胞内遺伝子発現制御機能性オリゴ核酸のRNAへの架橋形成による遺伝子発現制御2013
    • Author(s)
      萩原伸也、草野修平、井田裕太、岩本直生、永次史
    • Organizer
      日本化学会第93春季年会
    • Place of Presentation
      立命館大学、滋賀県
    • Data Source
      KAKENHI-PROJECT-23659002

  • [Presentation] Design of the efficient cross-linking agent with the fixed conformation2013
    • Author(s)
      Yuta Ida, Shuhei Kusano, Shinya Hagihara, Fumi Nagatsugi
    • Organizer
      Tohoku University Campus Asia Program Summer School 2013
    • Place of Presentation
      Sendai, Japan
    • Data Source
      KAKENHI-PROJECT-25288073

  • [Presentation] 2'位メトキシピリミジン型クロスリンク核酸の開発と評価2013
    • Author(s)
      秋島広佑、西本篤史、實崎大地、谷口陽祐、永次史、佐々木茂貴
    • Organizer
      第30回日本薬学会九州支部大会
    • Place of Presentation
      長崎（長崎国際大学）
    • Data Source
      KAKENHI-PROJECT-21229002

  • [Presentation] グアニンおよび8-オキソグアニンに対する架橋形成ピリミジン誘導体の反応性2013
    • Author(s)
      石山　翔午，草野　修平，永次　史
    • Organizer
      第３９回反応と合成の進歩シンポジウム
    • Place of Presentation
      九州大学 医学部 百年講堂、福岡