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Nishio Hiroshi  西尾 浩

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… Alternative Names

Hiroshi Nishio  西尾 浩

西尾 浩  ニシオ ヒロシ

NISHIO Hiroshi  西尾 浩

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Researcher Number 90445239
Other IDs
Affiliation (Current) 2025: 慶應義塾大学, 医学部(信濃町), 講師
Affiliation (based on the past Project Information) *help 2025: 慶應義塾大学, 医学部(信濃町), 講師
2021 – 2023: 慶應義塾大学, 医学部(信濃町), 講師
2019 – 2020: 慶應義塾大学, 医学部(信濃町), 助教
2015: 慶應義塾大学, 医学部, 特任助教
2013: 慶應義塾大学, 医学部, 助教 … More
2011: Keio University, 医学部, 研究員
2010: 慶應義塾大学, 医学部, 研究員(非常勤)
2008 – 2009: Keio University, 医学部, 助教 Less
Review Section/Research Field
Principal Investigator
Basic Section 56040:Obstetrics and gynecology-related / Obstetrics and gynecology
Keywords
Principal Investigator
免疫逃避 / 卵巣がん / 免疫療法 / 免疫寛容 / がん微小環境 / がん免疫療法 / 卵巣癌 / 免疫抑制 / がん免疫逃避 / 免疫チェックポイント … More / immunoescape / ovarian cancer / regulatory Tcell / immunotherapy / 制御性T細胞 / サイトカイン / STAT3 / NF-kB / HNF-1beta / 骨髄由来抑制細胞 / 免疫抑制サイトカイン / 腫瘍免疫 / HPV / MAPK / シグナル伝達系 / B7ファミリー / 腫瘍免疫学 / 子宮頸癌 Less
  • Research Projects

    (6 results)
  • Research Products

    (22 results)
  • Co-Researchers

    (9 People)
  •  婦人科がんにおけるがん免疫疲弊と免疫記憶の包括的理解と制御法の開発Principal Investigator

    • Principal Investigator
      西尾 浩
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Keio University
  •  卵巣がんにおける腫瘍浸潤T細胞の免疫不応状態の克服による複合的免疫療法の開発Principal Investigator

    • Principal Investigator
      西尾 浩
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Keio University
  •  Functional analysis of novel immune checkpoints and development of combined immunotherapy in gynecological cancerPrincipal Investigator

    • Principal Investigator
      Nishio Hiroshi
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Keio University
  •  Investigating cancer-immunoescape mechanism and effective immuunotherapy for ovarian cancerPrincipal Investigator

    • Principal Investigator
      Hiroshi Nishio
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Keio University
  •  婦人科癌における免役逃避機構の解明および新規解除方法の開発Principal Investigator

    • Principal Investigator
      西尾 浩
    • Project Period (FY)
      2010
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Keio University
  •  Analysis of immune escape mechanism in cervical cancer that aims at immunotherapeutic applicationPrincipal Investigator

    • Principal Investigator
      NISHIO Hiroshi
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Keio University

All 2024 2023 2022 2021 2020 2019 2016 2015 2013 2010 2009

All Journal Article Presentation

  • [Journal Article] Gastric-type adenocarcinoma of the uterine cervix: clinical features and future directions2024

    • Author(s)
      Nishio Hiroshi、Matsuda Risa、Iwata Takashi、Yamagami Wataru
    • Journal Title

      Japanese Journal of Clinical Oncology

      Volume: 54 Issue: 5 Pages: 516-520

    • DOI

      10.1093/jjco/hyae019

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K09604
  • [Journal Article] 当科で経験した子宮頸部胃型粘液性癌12例の検討2023

    • Author(s)
      木村由実子, 西尾浩, 千代田達幸, 松井友哉, 岩田卓, 椎名美季, 大野あゆみ, 横田めぐみ, 田中守, 青木大輔
    • Journal Title

      東京産科婦人科学会雑誌

      Volume: 72 Pages: 19-24

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K09604
  • [Journal Article] 卵巣がんに対する免疫チェックポイント阻害薬治療の開発2022

    • Author(s)
      西尾浩, 青木大輔
    • Journal Title

      腫瘍内科

      Volume: 30 Pages: 385-388

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K09604
  • [Journal Article] Transcription Factor Homeobox D9 Drives the Malignant Phenotype of HPV18-Positive Cervical Cancer Cells via Binding to the Viral Early Promoter2021

    • Author(s)
      Hayashi S, Iwata T, Imagawa R, Sugawara M, Chen G, Tanimoto S, Sugawara Y, Tanaka I, Matsui T, Nishio H, Nakamura M, Katoh Y, Mori S, Kukimoto I, Aoki D.
    • Journal Title

      Cancers (Basel)

      Volume: 13(18) Issue: 18 Pages: 4613-4613

    • DOI

      10.3390/cancers13184613

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K11309, KAKENHI-PROJECT-18K09244, KAKENHI-PROJECT-19K09832, KAKENHI-PROJECT-20K09682, KAKENHI-PROJECT-21K09461
  • [Journal Article] Meningitis caused by Listeria monocytogenes in a locally advanced cervical cancer patient with pyometra: A case report2021

    • Author(s)
      Matoba Yusuke、Nishio Hiroshi、Sekiguchi Koji、Uno Shunsuke、Masuda Kenta、Hiramatsu Makiko、Takahashi Mio、Oishi Maki、Uwamino Yoshifumi、Uchida Sho、Dat? Yugaku、Morisada Tohru、Banno Kouji、Nakahara Jin、Aoki Daisuke
    • Journal Title

      Gynecologic Oncology Reports

      Volume: 37 Pages: 100799-100799

    • DOI

      10.1016/j.gore.2021.100799

    • Data Source
      KAKENHI-PROJECT-19K09832
  • [Journal Article] Current status of cancer immunotherapy for gynecologic malignancies2021

    • Author(s)
      Hiroshi Nishio, Takashi Iwata, Daisuke Aoki
    • Journal Title

      Jpn J Clin Oncol

      Volume: 51 Issue: 2 Pages: 167-172

    • DOI

      10.1093/jjco/hyaa214

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K09832
  • [Journal Article] Tumor-infiltrating lymphocytes predict survival outcomes in patients with cervical cancer treated with concurrent chemoradiotherapy2020

    • Author(s)
      Akiko Ohno, Takashi Iwata, Yuki Katoh, Shiho Taniguchi, Kohsei Tanaka, Hiroshi Nishio, Masaru Nakamura , Tohru Morisada, Guanliang Chen, Miyuki Saito, Tomonori Yaguchi, Yutaka Kawakami, Daisuke Aoki
    • Journal Title

      Gynecol Oncol .

      Volume: 159 Issue: 2 Pages: 329-334

    • DOI

      10.1016/j.ygyno.2020.07.106

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K09832, KAKENHI-PROJECT-20H03534, KAKENHI-PROJECT-18K16813
  • [Journal Article] Transcription factor homeobox D9 is involved in the malignant phenotype of cervical cancer through direct binding to the human papillomavirus oncogene promoter2019

    • Author(s)
      Hirao N, Iwata T, Tanaka K, Nishio H, Nakamura M, Morisada T, Morii K, Maruyama N, Katoh Y, Yaguchi T, Ohta S, Kukimoto I, Aoki D, Kawakami Y.
    • Journal Title

      Gynecol Oncol

      Volume: 155 Issue: 2 Pages: 340-348

    • DOI

      10.1016/j.ygyno.2019.08.026

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K11309, KAKENHI-PROJECT-19K09832, KAKENHI-PROJECT-18K16813, KAKENHI-PROJECT-16H06276
  • [Journal Article] Pregnancy Outcomes After Abdominal Radical Trachelectomy for Early-Stage Cervical Cancer: A 13-Year Experience in a Single Tertiary-Care Center2016

    • Author(s)
      Kasuga Y, Nishio H, Miyakoshi K, Sato S, Sugiyama J, Matsumoto T, Tanaka K, Ochiai D, Minegishi K, Hamatani T, Iwata T, Morisada T, Nakamura M, Fujii T, Kuji N, Aoki D, Tanaka M
    • Journal Title

      Int J Gynecol Cancer

      Volume: 26 Issue: 1 Pages: 163-168

    • DOI

      10.1097/igc.0000000000000571

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26462540, KAKENHI-PROJECT-25462610, KAKENHI-PROJECT-25462614, KAKENHI-PROJECT-25293345, KAKENHI-PROJECT-16K15536
  • [Journal Article] p16(INK4a)immunohistochemistry is a promising biomarker to predict the outcome of low grade cervical intraepithelial neoplasia:comparison study with HPV genotyping2013

    • Author(s)
      Nishio S, Fujii T, Nishio H, Kameyama K, Saito M, Iwata T, Kubushiro K, Aoki D
    • Journal Title

      J Gynecol Oncol

      Volume: 24 Issue: 3 Pages: 215-221

    • DOI

      10.3802/jgo.2013.24.3.215

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592462, KAKENHI-PROJECT-25462614
  • [Journal Article] Reproductive and obstetric outcomes after radical abdominal trachelectomy for early-stage cervical cancer in a series of 31 pregnancies.2013

    • Author(s)
      Nishio H, Fujii T, Sugiyama J, Kuji N, Tanaka M, Hamatani T, Miyakoshi K, Minegishi K, Tsuda H, Iwata T, Tanaka K, Fukuchi T, Takehara Y, Yoshimura Y, Aoki D.
    • Journal Title

      Hum Reprod

      Volume: 28 Issue: 7 Pages: 1793-1798

    • DOI

      10.1093/humrep/det118

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592413, KAKENHI-PROJECT-23592462, KAKENHI-PROJECT-25293345, KAKENHI-PROJECT-25462614
  • [Journal Article] 化学療法・分子標的による抗腫瘍免疫応答の制御2013

    • Author(s)
      谷口智憲、里見良輔、西尾浩、杉山重里、大村学、川村直、小林明日香、河上裕
    • Journal Title

      実験医学

      Volume: 31 Pages: 1938-1944

    • Data Source
      KAKENHI-PROJECT-25462614
  • [Journal Article] Cancer-induced immunosuppressive cascades and their reversal by molecular-targeted therapy.2013

    • Author(s)
      Kawakami Y, Yaguchi T, Sumimoto H, Kudo-Saito C, Tsukamoto N, Iwata-Kajihara T, Nakamura S, Nishio H, Satomi R, Kobayashi A, Tanaka M, Hoon Park J, Kamijuku H, Tsujikawa T, Kawamura N
    • Journal Title

      Ann. N.Y. Acad. Sci.,

      Volume: 1284(1) Issue: 1 Pages: 80-86

    • DOI

      10.1111/nyas.12094

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23240128, KAKENHI-PROJECT-25430158, KAKENHI-PROJECT-25462614, KAKENHI-PROJECT-25670506, KAKENHI-PROJECT-25830122
  • [Presentation] A novel checkpoint molecule, neurotrophic factor X, is a promising immunotherapy target for ovarian cancer.2019

    • Author(s)
      Nishio Hiroshi, Iwata Takashi, Tanaka Kohsei, Saiki Naohiko, Nishio Sakiko, Nakamura Masaru, Morisada Tohru, Tanaka Mamoru, Aoki Daisuke.
    • Organizer
      第71回日本産科婦人科学会学術講演会
    • Data Source
      KAKENHI-PROJECT-19K09832
  • [Presentation] 子宮頸がん局所に浸潤するT細胞を用いた免疫療法の開発2015

    • Author(s)
      Sunthamala Nuchsupha、西尾 浩、谷口 智憲、岩田 卓、河上 裕、青木 大輔
    • Organizer
      婦人科がん分子標的研究会
    • Place of Presentation
      美ヶ原温泉ホテル(長野県松本市)
    • Year and Date
      2015-07-17
    • Data Source
      KAKENHI-PROJECT-25462614
  • [Presentation] 卵巣明細胞腺癌においてHNF-1βは腫瘍免疫の抑制に関与する2013

    • Author(s)
      杉山重里、西尾浩、岩田卓、谷口智憲、青木大輔、河上裕
    • Organizer
      第65回日本産科婦人科学会
    • Place of Presentation
      ロイトン札幌(北海道)
    • Data Source
      KAKENHI-PROJECT-25462614
  • [Presentation] ヒト卵巣癌における NF-κB活性化による免疫抑制誘導と NF-κB 阻害剤による改善2013

    • Author(s)
      西尾浩、谷口智憲、住本秀敏、梅澤一夫、岩田卓、藤井多久磨、青木大輔、河上裕
    • Organizer
      第72回日本癌学会
    • Place of Presentation
      パシフィコ横浜(神奈川)
    • Data Source
      KAKENHI-PROJECT-25462614
  • [Presentation] Immunosuppression through HNF-1b signaling in human ovarian clear cell cancer.2013

    • Author(s)
      Hiroshi Nishio1,2, Juri Sugiyama1,2, Tomonori Yaguch1, Takashi Iwata2, Daisuke Aoki2, Yutaka Kawakami1
    • Organizer
      /2013/28th Annual meeting of Society for Immunotherapy of Cancer
    • Place of Presentation
      Gaylord National Hotel & Convention Center(Washington)
    • Data Source
      KAKENHI-PROJECT-25462614
  • [Presentation] 活性化NF-kBの阻害により卵巣癌細胞株における免疫抑制環境は解除される2010

    • Author(s)
      西尾浩
    • Organizer
      第62回日本産婦人科学会学術講演会
    • Place of Presentation
      東京国際フォーラム
    • Year and Date
      2010-04-23
    • Data Source
      KAKENHI-PROJECT-22791546
  • [Presentation] Blockade of activated NF-kB in cancer cells and immune cells may eliminate immunosuppressive state in human ovarian cancer2010

    • Author(s)
      西尾浩
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪国際会議場
    • Year and Date
      2010-09-24
    • Data Source
      KAKENHI-PROJECT-22791546
  • [Presentation] 卵巣癌におけるNF-kBシグナルの亢進はIL-6の産生およびMDSCの誘導により免疫抑制に関与する2010

    • Author(s)
      西尾浩
    • Organizer
      第14回日本がん免疫学会
    • Place of Presentation
      KKR熊本
    • Year and Date
      2010-07-23
    • Data Source
      KAKENHI-PROJECT-22791546
  • [Presentation] 子宮頸癌細胞株におけるB7タンパクの発現解析~免疫療法にむけた基盤的研究~2009

    • Author(s)
      岩田卓 藤井多久磨 西尾浩 塚崎克己 青木大輔 吉村泰典
    • Organizer
      第61回日本産科婦人科学会総会学術集会
    • Place of Presentation
      京都
    • Year and Date
      2009-04-03
    • Data Source
      KAKENHI-PROJECT-20791163
  • 1.  IWATA TAKASHI (30296652)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 11 results
  • 2.  YAGUCHI TOMONORI (40424163)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 6 results
  • 3.  加藤 侑希 (60733649)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  KUDO Chie
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 5.  TSUKAMOTO Nobuo
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 6.  藤井 多久磨
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 7.  柊元 巌
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 8.  浜谷 敏生
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 9.  河上 裕
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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