Murakawa Takeshi 村川武志

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MURAKAWA Takeshi 村川武志

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Researcher Number	90445990
Other IDs	https://orcid.org/0000-0001-5905-532X
Affiliation (Current)	2025: 大阪医科薬科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 大阪医科薬科大学, 医学部, 助教 2007 – 2020: Osaka Medical College, 医学部, 助教
Review Section/Research Field	Principal Investigator Structural biochemistry / Complex systems / Medium-sized Section 43:Biology at molecular to cellular levels, and related fields / Basic Section 38030:Applied biochemistry-related / Basic Section 43020:Structural biochemistry-related / Functional biochemistry Except Principal Investigator Structural biochemistry / Basic Section 27040:Biofunction and bioprocess engineering-related / Basic Section 49060:Virology-related / Basic Section 38030:Applied biochemistry-related / Basic Section 37010:Bio-related chemistry / Transition State Control / Bio-related chemistry
Keywords	Principal Investigator トパキノン / アミン酸化酵素 / HAG法 / SFX / シリアルフェムト秒結晶構造解析 / 酵素 / X線結晶構造解析 / 中性子結晶構造解析 / 反応中間体 / 結晶 … More / 蛋白質 / 銅含有アミン酸化酵素 / Ｘ線 / 補酵素 / 中性子 / X線結晶構造回析 / 中性子結晶構造回析 / X線 / 中性子線 / 高分解能 / TPQ / 超高分解能X腺結晶構造解析 / 中性子線結晶構造解析 / 高分解能X線結晶解析 / ビルトイン補酵素 / 同位体効果 / ビルトインキノン補酵素 / プロトントンネリング … More Except Principal Investigator 補酵素 / ピリドキサールリン酸 / 遷移相速度論 / 酵素反応機構 / 銅アミン酸化酵素 / 反応機構 / 中性子構造解析 / 酵素 / ゆらぎ / 反応中間体 / 反応速度論 / X線結晶解析 / プロトン移動 / 湿度制御 / 試料環境制御 / 温度制御 / 非凍結結晶構造解析 / 温度環境 / 構造ダイナミクス / 結晶化温度 / タンパク質の機能 / X線結晶構造解析 / 細胞性因子 / 翻訳終結 / RNA / フラビウイルス / RyDEN / 極限環境タンパク質科学 / 極限環境生物 / 好熱菌 / 高温X線結晶構造解析 / 酸化反応 / 金属イオン / 翻訳後修飾 / 結晶構造解析 / 銅 / 中性子結晶構造 / 遷移状態 / ハロゲン化物イオン / 銅イオン / pH依存性 / 解離基 / トーパキノン / キノタンパク質 / 触媒反応機構 / 補欠分子族 / 反応駆動力 / エネルギー準位図 / 電子移動 / Ｘ線結晶解析 / 量子化学計算 / 副反応 / プロトン化状態 / ピリドキサール5'-リン酸 / 生成物支援触媒 / 基質支援触媒 / 反応特異性 / エネルギー進位 / 計算化学 / タンパク質のゆらぎ / 立体化学 / トレオニン合成酵素 / セリンパルミトイル転移酵素 / エネルギー準位 / キノン酵素 / ピリドキサール酵素 Less

Analysis of proton transfer in enzymatic reactions based on quantum theoryPrincipal Investigator
- Principal Investigator
  
  村川武志
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 38030:Applied biochemistry-related
- Research Institution
  Osaka Medical and Pharmaceutical University
High-Temperature X-ray Crystallography on the Proteins from Thermophiles, Opening the Way to Protein Science in Extreme Environments
- Principal Investigator
  
  福井健二
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38030:Applied biochemistry-related
- Research Institution
  Osaka Medical and Pharmaceutical University
Molecular characterisation of the RyDEN-based translation termination complex in the flavivirus RNA dysfunction
- Principal Investigator
  
  鈴木陽一
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  Osaka Medical and Pharmaceutical University
Real-time structural dynamics analysis of protein crystal structure by changing the environment (temperature/pH)
- Principal Investigator
  
  馬場清喜
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 27040:Biofunction and bioprocess engineering-related
- Research Institution
  Japan Synchrotron Radiation Research Institute
速度論および熱力学的手法を用いた"in crystallo" 酵素反応解析Principal Investigator
- Principal Investigator
  
  村川武志
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
- Research Institution
  Osaka Medical and Pharmaceutical University
シリアルフェムト秒結晶構造解析に基づく銅含有アミン酸化酵素の触媒機構の解明Principal Investigator
- Principal Investigator
  
  村川武志
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Osaka Medical and Pharmaceutical University
非凍結結晶を用いた“in crystallo”酵素反応解析Principal Investigator
- Principal Investigator
  
  村川武志
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  Osaka Medical and Pharmaceutical University
シリアルフェムト秒結晶構造解析による銅含有アミン酸化酵素の触媒機構の解明Principal Investigator
- Principal Investigator
  
  村川武志
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Osaka Medical and Pharmaceutical University
Elucidation of quinone cofactor biogenesis in copper amine oxidase on the basis of proton structures and flexibility analysis
- Principal Investigator
  
  Okajima Toshihide
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 37010:Bio-related chemistry
- Research Institution
  Osaka University
In crystallo thermodynamic analysis of the cofactor conformational change of copper amine oxidasePrincipal Investigator
- Principal Investigator
  
  Murakawa Takeshi
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Osaka Medical College
Elucidation of enzyme catalytic mechanism regulating transition state by linking conformational change and fluctuations of the active site
- Principal Investigator
  
  Okajima Toshihide
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Transition State Control
- Research Institution
  Osaka University
Concerted proton/electron transfer mechanism in cofactor-dependent enzyme
- Principal Investigator
  
  HAYASHI Hideyuki
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bio-related chemistry
- Research Institution
  Osaka Medical College
X-ray and neutron crystallographic structure of copper amine oxidasePrincipal Investigator
- Principal Investigator
  
  Murakawa Takeshi
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Osaka Medical College
Reaction specificity of pyridoxal enzymes
- Principal Investigator
  
  Hayashi Hideyuki
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Osaka Medical College
Structural studies for the refined reaction mechanism of copper amine oxidase.Principal Investigator
- Principal Investigator
  
  TAKESHI Murakawa
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Osaka Medical College
Multidimensional energy analysis of pyridoxal-enzyme and quinoenzyme reactions
- Principal Investigator
  
  HAYASHI Hideyuki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Osaka Medical College
Kinetic and X-ray crystallographic analysis of quantum mechanical hydrogen tunneling in enzyme-catalyzed reactionPrincipal Investigator
- Principal Investigator
  
  MURAKAWA Takeshi
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Osaka Medical College

[Journal Article] Neutron Crystallography of a Semiquinone Radical Intermediate of Copper Amine Oxidase Reveals a Substrate-Assisted Conformational Change of the Peptidyl Quinone Cofactor2023
- Author(s)
  Murakawa Takeshi、Kurihara Kazuo、Shoji Mitsuo、Yano Naomine、Kusaka Katsuhiro、Kawano Yoshiaki、Suzuki Mamoru、Shigeta Yasuteru、Yano Takato、Adachi Motoyasu、Tanizawa Katsuyuki、Okajima Toshihide
- Journal Title
  
  ACS Catalysis
  
  Volume: 13 Issue: 18 Pages: 12403-12413
- DOI
  10.1021/acscatal.3c02629
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K18117, KAKENHI-PROJECT-20K06530, KAKENHI-PROJECT-20K06238, KAKENHI-PLANNED-20H05453, KAKENHI-PUBLICLY-22H04757
[Journal Article] Serial femtosecond X-ray crystallography of an anaerobically formed catalytic intermediate of copper amine oxidase2022
- Author(s)
  Murakawa Takeshi、Suzuki Mamoru、Fukui Kenji、Masuda Tetsuya、Sugahara Michihiro、Tono Kensuke、Tanaka Tomoyuki、Iwata So、Nango Eriko、Yano Takato、Tanizawa Katsuyuki、Okajima Toshihide
- Journal Title
  
  Acta Crystallographica Section D Structural Biology
  
  Volume: 78 Issue: 12 Pages: 1428-1438
- DOI
  10.1107/s2059798322010385
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06238, KAKENHI-PROJECT-20K06530, KAKENHI-PROJECT-19H00923, KAKENHI-PLANNED-19H05781, KAKENHI-PUBLICLY-22H04757, KAKENHI-PLANNED-19H05777
[Journal Article] Molecular mechanism of a large conformational change of the quinone cofactor in the semiquinone intermediate of bacterial copper amine oxidase2022
- Author(s)
  Shoji Mitsuo、Murakawa Takeshi、Nakanishi Shota、Boero Mauro、Shigeta Yasuteru、Hayashi Hideyuki、Okajima Toshihide
- Journal Title
  
  Chemical Science
  
  Volume: 13 Issue: 36 Pages: 10923-10938
- DOI
  10.1039/d2sc01356h
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06530, KAKENHI-PROJECT-22H04916, KAKENHI-PLANNED-20H05453, KAKENHI-PUBLICLY-22H04757, KAKENHI-PUBLICLY-22H04800
[Journal Article] Re-evaluation of protein neutron crystallography with and without X-ray/neutron joint refinement2022
- Author(s)
  Murakawa Takeshi、Kurihara Kazuo、Adachi Motoyasu、Kusaka Katsuhiro、Tanizawa Katsuyuki、Okajima Toshihide
- Journal Title
  
  IUCrJ
  
  Volume: 9 Issue: 3 Pages: 342-348
- DOI
  10.1107/s2052252522003657
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K05694, KAKENHI-PROJECT-20K06530, KAKENHI-PUBLICLY-22H04757
[Journal Article] Microcrystal preparation for serial femtosecond X-ray crystallography of bacterial copper amine oxidase2021
- Author(s)
  Murakawa Takeshi、Suzuki Mamoru、Arima Toshi、Sugahara Michihiro、Tanaka Tomoyuki、Tanaka Rie、Iwata So、Nango Eriko、Tono Kensuke、Hayashi Hideyuki、Fukui Kenji、Yano Takato、Tanizawa Katsuyuki、Okajima Toshihide
- Journal Title
  
  Acta Crystallographica Section F Structural Biology Communications
  
  Volume: 77 Issue: 10 Pages: 356-363
- DOI
  10.1107/s2053230x21008967
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K05694, KAKENHI-PLANNED-19H05781, KAKENHI-PUBLICLY-20H05448, KAKENHI-PROJECT-19H00923, KAKENHI-PROJECT-20K06238, KAKENHI-PROJECT-20K06530, KAKENHI-PLANNED-19H05777
[Journal Article] X-Ray and Neutron Joint Refinement Displays Shared Proton and Keto Form of Quinone Cofactor in Copper Amine Oxidase2021
- Author(s)
  Murakawa Takeshi、Kurihara Kazuo、Kusaka Katsuhiro、Okajima Toshihide、Adachi Motoyasu
- Journal Title
  
  Photon Factory Highlights 2020
  
  Volume: 6 Pages: 42-43
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K05694
[Journal Article] Neutron Crystallography Reveals Unprecedented Active-site Structure in Copper Amine Oxidase2021
- Author(s)
  Murakawa Takeshi、Kurihara Kazuo、Tamada Taro、Kusaka Katsuhiro、Adachi Motoyasu、Okajima Toshihide
- Journal Title
  
  J-PARC MLF ANNUAL REPORT
  
  Volume: 12 Pages: 14-16
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K05694
[Journal Article] Unique protonation states of aspartate and topaquinone in the active site of copper amine oxidase2020
- Author(s)
  Shoji Mitsuo、Murakawa Takeshi、Boero Mauro、Shigeta Yasuteru、Hayashi Hideyuki、Okajima Toshihide
- Journal Title
  
  RSC Advances
  
  Volume: 10 Issue: 63 Pages: 38631-38639
- DOI
  10.1039/d0ra06365g
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K05694, KAKENHI-PROJECT-20K06530, KAKENHI-PUBLICLY-20H05088, KAKENHI-PUBLICLY-20H05448, KAKENHI-PLANNED-20H05453, KAKENHI-PUBLICLY-20H05497, KAKENHI-PROJECT-17K07317
[Journal Article] In crystallo thermodynamic analysis of the catalytic reaction in bacterial copper amine oxidase2020
- Author(s)
  Takeshi Murakawa, Seiki Baba, Toshihide Okajima
- Journal Title
  
  SPring-8/SACLA Research Frontiers
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16KT0055
[Journal Article] Neutron crystallography of copper amine oxidase reveals keto/enolate interconversion of the quinone cofactor and unusual proton sharing2020
- Author(s)
  Takeshi Murakawa, Kazuo Kurihara, Mitsuo Shoji, Chie Shibazaki, Tomoko Sunami, Taro Tamada, Naomine Yano, Taro Yamada, Katsuhiro Kusaka, Mamoru Suzuki, Yasuteru Shigeta, Ryota Kuroki, Hideyuki Hayashi, Takato Yano, Katsuyuki Tanizawa, Motoyasu Adachi, Toshihide Okajima
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 印刷中 Issue: 20 Pages: 10818-10824
- DOI
  10.1073/pnas.1922538117
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K05694, KAKENHI-PROJECT-16KT0055, KAKENHI-PROJECT-20K06238, KAKENHI-PUBLICLY-19H05047, KAKENHI-PUBLICLY-20H05497
[Journal Article] 宙に浮く水素イオン？！－大型タンパク質の中性子結晶構造解析で見えた特異な世界－（4月28日、プレス発表）2020
- Author(s)
  村川武志、栗原和男、庄司光男、柴崎千枝、角南智子、玉田太郎、矢野直峰、山田太郎、日下勝弘、鈴木　守、重田育照、黒木良太、林　秀行、矢野貴人、谷澤克行、安達基泰、岡島俊英
- Journal Title
  
  J-PARC News
  
  Volume: 181 Pages: 2-2
- Data Source
  KAKENHI-PROJECT-19K05694
[Journal Article] In crystallo thermodynamic analysis of the catalytic reaction in bacterial copper amine oxidase2020
- Author(s)
  Takeshi Murakawa, Seiki Baba, Toshihide Okajima
- Journal Title
  
  SPring-8/SACLA Research Frontiers
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K05694
[Journal Article] In crystallo thermodynamic analysis of the catalytic reaction in bacterial copper amine oxidase2020
- Author(s)
  Takeshi Murakawa, Seiki Baba,Toshihide Okajima
- Journal Title
  
  SPring-8/SACLA Research Frontiers 2019
  
  Volume: 1 Pages: 20-21
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K05694
[Journal Article] In crystallo thermodynamic analysis of the cofactor conformational change induced during the catalytic reaction of copper amine oxidase2019
- Author(s)
  村川武志，馬場清喜，岡島俊英
- Journal Title
  
  生化学
  
  Volume: 91 Issue: 4 Pages: 565-571
- DOI
  10.14952/SEIKAGAKU.2019.910565
- NAID
  40022022855
- ISSN
  0037-1017
- Year and Date
  2019-08-25
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K05694, KAKENHI-PROJECT-16KT0055
[Journal Article] In crystallo thermodynamic analysis of conformational change of the topaquinone cofactor in bacterial copper amine oxidase2018
- Author(s)
  Murakawa Takeshi、Baba Seiki、Kawano Yoshiaki、Hayashi Hideyuki、Yano Takato、Kumasaka Takashi、Yamamoto Masaki、Tanizawa Katsuyuki、Okajima Toshihide
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 116 Issue: 1 Pages: 135-140
- DOI
  10.1073/pnas.1811837116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16KT0055, KAKENHI-PROJECT-17K07317, KAKENHI-PROJECT-15K05573
[Journal Article] Molecular Mechanism of the Reaction Specificity in Threonine Synthase: Importance of the Substrate Conformations2017
- Author(s)
  Ujiie Yuzuru，Tanaka Wataru，Hanaoka Kyohei，Harada Ryuhei，Kayanuma Megumi，Shoji Mitsuo，Murakawa Takeshi，Ishida Toyokazu，Shigeta Yasuteru，Hayashi Hideyuki
- Journal Title
  
  The Journal of Physical Chemistry B
  
  Volume: 121 Issue: 22 Pages: 5536-5543
- DOI
  10.1021/acs.jpcb.7b02932
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K05573, KAKENHI-PROJECT-16H06164, KAKENHI-PROJECT-15J03797
[Journal Article] Probing the Catalytic Mechanism of Copper Amine Oxidase from Arthrobacter globiformis with Halide Ions.2015
- Author(s)
  Murakawa, T., Hamaguchi, A., Nakanishi, S., Kataoka, M., Nakai, T., Kawano, Y., Yamaguchi, H., Hayashi, H., Tanizawa, K., and Okajima, T.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 290 Issue: 38 Pages: 23094-23109
- DOI
  10.1074/jbc.m115.662726
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K05573, KAKENHI-PROJECT-15K07391, KAKENHI-PROJECT-26440037
[Journal Article] A QM/MM Study of the l-Threonine Formation Reaction of Threonine Synthase: Implications into the Mechanism of the Reaction Specificity.2014
- Author(s)
  Shoji, M., Hanaoka, K., Ujiie, Y., Tanaka, W., Kondo, D., Umeda, H., Kamoshida, Y., Kayanuma, M., Kamiya, K., Shiraishi, K., Machida, Y., Murakawa, T., and Hayashi, H.
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 136 Issue: 12 Pages: 4525-4533
- DOI
  10.1021/ja408780c
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24570140, KAKENHI-PROJECT-24750007
[Journal Article] High-resolution crystal structure of copper amine oxidase from Arthrobacter globiformis : assignment of bound diatomic molecules as O_22013
- Author(s)
  Murakawa T, Hayashi H, Sunami T, Kurihara K, Tamada T, Kuroki R, Suzuki M, Tanizawa K, Okajima T.
- Journal Title
  
  Acta Crystallogr D Biol Crystallogr
  
  Volume: 69 Pages: 2483-94
- Data Source
  KAKENHI-PROJECT-23770127
[Journal Article] High-resolution crystal structure of copper amine oxidase from Arthrobacter globiformis: assignment of bound diatomic molecules as O22013
- Author(s)
  Murakawa T, Hayashi H, Sunami T, Kurihara K, Tamada T, Kuroki R, Suzuki M, Tanizawa K, Okajima T.
- Journal Title
  
  Acta Crystallographica Section D
  
  Volume: 69 Issue: 12 Pages: 2483-2494
- DOI
  10.1107/s0907444913023196
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23770127
[Journal Article] Structural insights into the substrate specificity of bacterial copper amine oxidase obtained by using irreversible inhibitors2012
- Author(s)
  Murakawa T, Hayashi H, Taki M, Yamamoto Y, Kawano Y, Tanizawa K, Okajima T.
- Journal Title
  
  J. Biochem.
  
  Volume: 151 Pages: 167-78
- NAID
  10031166055
- Data Source
  KAKENHI-PROJECT-23770127
[Journal Article] Structural insights into the substrate specificity of bacterial copper amine oxidase obtained by using irreversible inhibitors2012
- Author(s)
  Hideyuki Hayashi, Takeshi Murakawa
- Journal Title
  
  J.Biochem.
  
  Volume: 151 Issue: 2 Pages: 167-178
- DOI
  10.1093/jb/mvr125
- NAID
  10031166055
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570120, KAKENHI-PROJECT-23685039
[Journal Article] Structural insights into the substrate specificity of bacterial copper amine oxidase obtained by using irreversible inhibitors2012
- Author(s)
  Murakawa T, Hayashi H, Taki M, Yamamoto Y, Kawano Y, Tanizawa K, Okajima T.
- Journal Title
  
  J Biochem
  
  Volume: 151 Pages: 167-178
- NAID
  10031166055
- Data Source
  KAKENHI-PROJECT-21570120
[Journal Article] Structural insights into the substrate specificity of bacterial copper amine oxidase obtained by using irreversible inhibitors.2012
- Author(s)
  Takeshi Murakawa, Hideyuki Hayashi, Masayasu Taki,Yukio Yamamoto, Yoshiaki Kawano, Katsuyuki Tanizawa, Toshihide Okajima.
- Journal Title
  
  THE JOURNAL OF BIOCHEMISTRY
  
  Volume: 15 Pages: 167-178
- NAID
  10031166055
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23770127
[Journal Article] Product-assisted catalysis as the basis of the reaction specificity of threonine synthase2011
- Author(s)
  Murakawa
- Journal Title
  
  J.Biol.Chem.
  
  Volume: 286 Pages: 2774-2784
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570120
[Journal Article] Product-assisted catalysis as the basis of the reaction specificity of threonine synthase2011
- Author(s)
  Murakawa, T., Machida, Y., Hideyuki Hayashi
- Journal Title
  
  J. Biol. Chem
  
  Volume: 286 Pages: 2774-2784
- Data Source
  KAKENHI-PROJECT-21570120
[Journal Article] Structural insights into the enzymatic mechanism of serine palmitoyltransferase from Sphingobacterium multivorum2009
- Author(s)
  Ikushiro, H., Islam, M. M., Okamoto, A., Hoseki, J., Murakawa, T., Fujii, S., Miyahara, I., Hayashi, H.
- Journal Title
  
  J Biochem
  
  Volume: 146 Pages: 549-562
- NAID
  10026304060
- Data Source
  KAKENHI-PROJECT-21570120
[Journal Article] Further insight into the mechanism of streoselective proton abstraction by bacterial copper amine oxidase2008
- Author(s)
  Masayasu Taki, Takeshi Murakawa (equally contributing), Takuya Nakamoto, Mayumi Uchida, Hideyuki Hayashi, Katsuyuki Tanizawa, Yukio Yamamoto, Toshihide Okajima
- Journal Title
  
  Biochemistry 47
  
  Pages: 7726-7733
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770118
[Journal Article] Further insight into the mechanism of streoselective proton abstraction by bacterial copper amine oxidase2008
- Author(s)
  Masayasu Taki, Takeshi Murakawa (equally contributing)
- Journal Title
  
  Biochemistry 47
  
  Pages: 7726-7733
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770118
[Presentation] Molecular movie of the catalytic reaction of bacterial copper amine oxidase conducted by mix-and-inject serial femtosecond X-ray crystallography2023
- Author(s)
  Takeshi Murakawa
- Organizer
  Molecular Movie” International Symposium 2023
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06530
[Presentation] Molecular movie of the catalytic reaction of bacterial copper amine oxidase conducted by mix-and-inject serial femtosecond X-ray crystallography2023
- Author(s)
  Takeshi Murakawa
- Organizer
  Molecular Movie” International Symposium 2023
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K18117
[Presentation] 銅含有アミン酸化酵素の中性子結晶構造解析2023
- Author(s)
  村川武志，栗原和男，日下勝弘，安達基泰，岡島俊英
- Organizer
  2023年度量子ビームサイエンスフェスタ
- Data Source
  KAKENHI-PROJECT-20K06530
[Presentation] 銅含有アミン酸化酵素の中性子結晶構造解析2023
- Author(s)
  村川武志，栗原和男，日下勝弘，安達基泰，岡島俊英
- Organizer
  2023年度量子ビームサイエンスフェスタ
- Data Source
  KAKENHI-PROJECT-23K18117
[Presentation] 銅含有アミン酸化酵素の中性子結晶構造解析2023
- Author(s)
  村川武志，栗原和男，日下勝弘，安達基泰，岡島俊英
- Organizer
  2023年度量子ビームサイエンスフェスタ
- Data Source
  KAKENHI-PUBLICLY-22H04757
[Presentation] Molecular movie of the catalytic reaction of bacterial copper amine oxidase conducted by mix-and-inject serial femtosecond X-ray crystallography2023
- Author(s)
  Takeshi Murakawa
- Organizer
  “Molecular Movie” International Symposium 2023
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-22H04757
[Presentation] シリアルフェムト秒結晶構造解析に基づく銅含有アミン酸化酵素触媒機構の解明2023
- Author(s)
  村川武志，鈴木守，福井健二，桝田哲哉，宮原郁子，溝端栄一，羅方佳，姜正敏，岩田想，南後恵理子，矢野貴人，當舎武彦，谷澤克行，岡島俊英
- Organizer
  令和5度新学術領域研究領域会議
- Data Source
  KAKENHI-PUBLICLY-22H04757
[Presentation] Molecular movie of the catalytic reaction of bacterial copper amine oxidase conducted by mix-and-inject serial femtosecond X-ray crystallography2022
- Author(s)
  Takeshi Murakawa
- Organizer
  10th Asian Biological Inorganic Chemistry Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-22H04757
[Presentation] Molecular movie of the catalytic reaction of bacterial copper amine oxidase conducted by mix-and-inject serial femtosecond X-ray crystallography2022
- Author(s)
  Takeshi Murakawa
- Organizer
  10th Asian Biological Inorganic Chemistry Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06530
[Presentation] 二液混合シリアルフェムト秒X線結晶構造解析に基づく銅含有アミン酸化酵素触媒機構の解明2022
- Author(s)
  村川武志
- Organizer
  日本放射光学会
- Invited
- Data Source
  KAKENHI-PROJECT-20K06530
[Presentation] 二液混合シリアルフェムト秒X線結晶構造解析に基づく銅含有アミン酸化酵素触媒機構の解明村川武志2022
- Author(s)
  村川武志
- Organizer
  日本蛋白質科学会
- Invited
- Data Source
  KAKENHI-PROJECT-20K06530
[Presentation] 二液混合シリアルフェムト秒X線結晶構造解析に基づく銅含有アミン酸化酵素触媒機構の解明2022
- Author(s)
  村川武志
- Organizer
  日本放射光学会
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H05448
[Presentation] 二液混合シリアルフェムト秒X線結晶構造解析に基づく銅含有アミン酸化酵素触媒機構の解明2022
- Author(s)
  村川武志
- Organizer
  日本蛋白質科学会
- Invited
- Data Source
  KAKENHI-PUBLICLY-22H04757
[Presentation] 銅含有アミン酸化酵素の中性子結晶構造解析2021
- Author(s)
  村川武志，栗原和男，安達基泰，日下勝弘，岡島俊英
- Organizer
  日本結晶学会
- Data Source
  KAKENHI-PUBLICLY-20H05448
[Presentation] 高分解能中性子結晶構造解析に基づく銅含有アミン酸化酵素の触媒機構2021
- Author(s)
  村川武志
- Organizer
  iBIXタンパク質構造研究会
- Invited
- Data Source
  KAKENHI-PROJECT-20K06530
[Presentation] シリアルフェムト秒結晶構造解析による銅含有アミン酸化酵素の触媒機構の解明2021
- Author(s)
  村川武志
- Organizer
  日本生化学会
- Invited
- Data Source
  KAKENHI-PROJECT-20K06530
[Presentation] シリアルフェムト秒結晶構造解析による銅含有アミン酸化酵素の触媒機構の解明2021
- Author(s)
  村川武志
- Organizer
  日本生化学会
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H05448
[Presentation] 高分解能中性子結晶構造解析に基づく銅含有アミン酸化酵素の触媒機構2021
- Author(s)
  村川武志
- Organizer
  iBIXタンパク質構造研究会
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H05448
[Presentation] 銅含有アミン酸化酵素の中性子結晶構造解析2021
- Author(s)
  村川武志，栗原和男，安達基泰，日下勝弘，岡島俊英
- Organizer
  日本結晶学会
- Data Source
  KAKENHI-PROJECT-20K06530
[Presentation] 銅アミン酸化酵素のトパキノン補酵素生合成反応における中間体形成の分光学的解析・速度論的解析2020
- Author(s)
  酒井克輝、佐々木康、村川武志、谷澤克行、岡島俊英
- Organizer
  日本農芸化学会2020年度大会
- Data Source
  KAKENHI-PROJECT-16KT0055
[Presentation] QM/MM法による銅アミン酸化酵素のプロトン化状態についての理論解析2020
- Author(s)
  庄司光男、村川武志、重田育照、林秀行、岡島俊英
- Organizer
  第34回分子シミュレーション討論会
- Data Source
  KAKENHI-PUBLICLY-20H05448
[Presentation] 銅アミン酸化酵素のトパキノン補酵素生合成反応における中間体形成の分光学的解析・速度論的解析2020
- Author(s)
  酒井克輝、佐々木康、村川武志、谷澤克行、岡島俊英
- Organizer
  日本農芸化学会2020年度大会
- Data Source
  KAKENHI-PROJECT-19K05694
[Presentation] シリアルフェムト秒結晶構造解析による銅含有アミン酸化酵素の触媒機構の解明2020
- Author(s)
  村川武志
- Organizer
  令和二年度新学術領域研究「高速分子動画」シンポジウム
- Data Source
  KAKENHI-PUBLICLY-20H05448
[Presentation] 銅アミン酸化酵素のプロトン化状態についてのQM/MM解析2020
- Author(s)
  庄司光男、村川武志、重田育照、林秀行、岡島俊英
- Organizer
  量子生命科学会第２回大会
- Data Source
  KAKENHI-PROJECT-19K05694
[Presentation] QM/MM法による銅アミン酸化酵素のプロトン化状態についての理論解析2020
- Author(s)
  庄司光男、村川武志、重田育照、林秀行、岡島俊英
- Organizer
  第34回分子シミュレーション討論会
- Data Source
  KAKENHI-PROJECT-19K05694
[Presentation] 銅含有アミン酸化酵素触媒機構の ”in crystallo” 熱力学的解析2019
- Author(s)
  村川武志
- Organizer
  大阪大学蛋白質研究所セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-17K07317
[Presentation] Structural basis for conformational change of the topaquinone cofactor during the catalytic reaction of bacterial copper amine oxidase2019
- Author(s)
  Toshihide Okajima, Takeshi Murakawa, Seiki Baba, Satoshi Kanagawa, Hideyuki Hayashi, Takato Yano, Takashi Kumasaka, and Katsuyuki Tanizawa
- Organizer
  33rd Annual Symposium of The Protein Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K05694
[Presentation] Structural basis for conformational change of the topaquinone cofactor during the catalytic reaction of bacterial copper amine oxidase2019
- Author(s)
  Toshihide Okajima, Takeshi Murakawa, Seiki Baba, Satoshi Kanagawa, Hideyuki Hayashi, Takato Yano, Takashi Kumasaka, and Katsuyuki Tanizawa
- Organizer
  33rd Annual Symposium of The Protein Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16KT0055
[Presentation] 銅含有アミン酸化酵素触媒機構の“in crystallo” 熱力学的解析2019
- Author(s)
  村川武志
- Organizer
  第42回 SPring-8先端利用技術ワークショップ/大阪大学蛋白質研究所セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-16KT0055
[Presentation] 銅含有アミン酸化酵素触媒機構の“in crystallo”熱力学的解析2019
- Author(s)
  村川武志，馬場清喜，河野能顕，林秀行，矢野貴人，熊坂崇，山本雅貴，谷澤克行，岡島俊英
- Organizer
  日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-17K07317
[Presentation] 銅含有アミン酸化酵素触媒機構の“in crystallo” 熱力学的解析2019
- Author(s)
  村川武志
- Organizer
  第42回 SPring-8先端利用技術ワークショップ/大阪大学蛋白質研究所セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-19K05694
[Presentation] 銅アミン酸化酵素の基質アミン複合体構造に基づく基質認識機構の解析2018
- Author(s)
  金川哲士，村川武志，谷澤克行，岡島俊英
- Organizer
  第18回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-16KT0055
[Presentation] ヒスチジノールリン酸アミノトランスフェラーゼの基質認識機構2018
- Author(s)
  林秀行，村川武志
- Organizer
  日本化学会第98春季年会
- Data Source
  KAKENHI-PROJECT-15K05573
[Presentation] 銅アミン酸化酵素の補酵素生合成における初期反応中間体の解析2018
- Author(s)
  佐々木康，村川武志，谷澤克行，岡島俊英
- Organizer
  酵素補酵素研究会2018
- Data Source
  KAKENHI-PROJECT-16KT0055
[Presentation] 銅含有アミン酸化酵素におけるセミキノンラジカル生成機構についての理論的解明2018
- Author(s)
  庄司光男, 村川武志, 重田育照, 岡島俊英
- Organizer
  分子シミュレーション討論会
- Data Source
  KAKENHI-PROJECT-16KT0055
[Presentation] In crystallo thermodynamic analysisによる銅アミン酸化酵素の反応機構解析2018
- Author(s)
  村川武志
- Organizer
  酵素補酵素研究会2018
- Data Source
  KAKENHI-PROJECT-16KT0055
[Presentation] In crystallo thermodynamic analysisによる銅アミン酸化酵素の反応機構解析2018
- Author(s)
  村川武志，馬場清喜，河野能顕，林秀行，矢野貴人，熊坂崇，山本雅貴，谷澤克行，岡島俊英，
- Organizer
  酵素補酵素研究会
- Data Source
  KAKENHI-PROJECT-17K07317
[Presentation] トレオニン合成酵素の反応機構2018
- Author(s)
  町田康博，村川武志，境晶子，林秀行
- Organizer
  日本ビタミン学会第70回大会
- Data Source
  KAKENHI-PROJECT-15K05573
[Presentation] 銅アミン酸化酵素の補酵素生合成における初期反応中間体の解析2018
- Author(s)
  佐々木康，村川武志，谷澤克行，岡島俊英,
- Organizer
  酵素補酵素研究会
- Data Source
  KAKENHI-PROJECT-17K07317
[Presentation] 銅アミン酸化酵素の基質アミン複合体構造に基づく基質認識機構及び基質特異性の改変2018
- Author(s)
  金川哲士，村川武志，谷澤克行，岡島俊英
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-16KT0055
[Presentation] 銅含有アミン酸化酵素における触媒反応中のプロトン化状態についての理論的解明2017
- Author(s)
  庄司光男，村川武志，重田育照，岡島俊英
- Organizer
  第１７回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-17K07317
[Presentation] 銅アミン酸化酵素活性中心の高分解能 X 線および中性子結晶構造2017
- Author(s)
  岡島俊英、村川武志、栗原和男、安達基泰、柴崎千枝、玉田太郎、林秀行、谷澤克行
- Organizer
  第8回MLFシンポジウム
- Place of Presentation
  つくば
- Year and Date
  2017-03-14
- Invited
- Data Source
  KAKENHI-PROJECT-16KT0055
[Presentation] 銅含有アミン酸化酵素における触媒反応中のプロトン化状態についての理論的解明2017
- Author(s)
  庄司光男, 村川武志, 重田育照, 岡島俊英
- Organizer
  第17回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-16KT0055
[Presentation] 銅含有アミン酸化酵素における触媒反応中のプロトン化状態についての理論的解明2017
- Author(s)
  庄司光男，村川武志，重田育照，岡島俊英
- Organizer
  第１７回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-26440037
[Presentation] Analysis of the Catalytic Mechanism of Copper Amine Oxidase from Arthrobacter globiformis.2016
- Author(s)
  H. Yamaguchi, T. Murakawa, M. Kataoka, Y. Kawano, H. Hayashi, K. Tanizawa and T. Okajima
- Organizer
  International Symposium on Diffraction Structural Biology 2016
- Place of Presentation
  Knoxville, Tennessee, U.S.A
- Year and Date
  2016-08-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16KT0055
[Presentation] 2.Analysis of the Catalytic Mechanism of Copper Amine Oxidase from Arthrobacter Globiformis.2016
- Author(s)
  Hiroshi Yamaguchi, Takeshi Murakawa, Misumi Kataoka, Yoshiaki Kawano, Hideyuki Hayashi, Katsuyuki Tanizawa, and Toshihide Okajima.
- Organizer
  ISDSB2016
- Place of Presentation
  Tennessee, USA.
- Year and Date
  2016-08-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26440037
[Presentation] X-ray crystallographic structure of semiquinone radical intermediate formed in bacterial copper amine oxidase.2016
- Author(s)
  Toshihide Okajima, Tadashi Nakai1 , Katsuyuki Tanizawa , Takeshi Murakawa , and Hideyuki Hayashi.
- Organizer
  ICC05-AEM2016
- Place of Presentation
  Unazuki, Japan.
- Year and Date
  2016-09-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26440037
[Presentation] Strain as the driving force for catalysis in aspartate aminotransferase2016
- Author(s)
  Hideyuki Hayashi and Takeshi Murakawa
- Organizer
  V Russian Congress on Biochemistry
- Place of Presentation
  Sochi, Russian Federation
- Year and Date
  2016-10-04
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K05573
[Presentation] X-ray crystallographic structure of semiquinone radical intermediate formed in bacterial copper amine oxidase2016
- Author(s)
  T. Okajima, T. Nakai, K. Tanizawa, T. Murakawa, and H. Hayashi
- Organizer
  Fifth International Conference on Cofactors (ICC-05) & Active Enzyme Molecule 2016
- Place of Presentation
  黒部
- Year and Date
  2016-09-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16KT0055
[Presentation] スレオニン合成酵素における生成物支援機構の理論的解明2016
- Author(s)
  氏家謙、庄司光男、原田隆平、村川武志、重田育照、林秀行
- Organizer
  第５４回生物物理会年会
- Place of Presentation
  つくば
- Year and Date
  2016-11-25
- Data Source
  KAKENHI-PROJECT-16KT0055
[Presentation] トレオニン合成酵素における生成物支援触媒機構についての理論的解明2015
- Author(s)
  庄司光男，氏家謙，栢沼愛，重田育照，村川武志，林秀行
- Organizer
  第53回日本生物物理学会年会
- Place of Presentation
  金沢
- Year and Date
  2015-09-13
- Data Source
  KAKENHI-PROJECT-24570140
[Presentation] Molecular dynamics study on the key catalytic intermediates of threonine synthase2015
- Author(s)
  Mitsuo Shoji, Yuzuru Ujiie, Ryuhei Harada, Megumi Kayanuma, Yasuteru Shigeta, Takeshi Murakawa, Hideyuki Hayashi
- Organizer
  The 29th Annual Symposium of the Protein Society
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2015-07-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24570140
[Presentation] 銅含有アミン酸化酵素の大型結晶調製と予備的中性子回折実験2015
- Author(s)
  村川武志
- Organizer
  茨城県平成２７年度第３回(第11 回) iBIX 研究会
- Place of Presentation
  茨城県東海村
- Year and Date
  2015-10-28
- Invited
- Data Source
  KAKENHI-PROJECT-26440037
[Presentation] Molecular dynamics study on the molecular mechanism of product-assisted catalysis in threonine synthase2015
- Author(s)
  氏家謙，田中弥，庄司光男，原田隆平，栢沼愛，重田育照，村川武志，林秀行
- Organizer
  第43回構造活性相関シンポジウム・第10回薬物の分子設計と開発に関する日中シンポジウム
- Place of Presentation
  新潟
- Year and Date
  2015-09-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24570140
[Presentation] Energetics of the proton-transfer mechanism in aspartate aminotransferase2015
- Author(s)
  Hideyuki Hayashi, Takeshi Murakawa, Mitsuo Shoji, Yasuteru Shigeta
- Organizer
  Pacifichem 2015
- Place of Presentation
  Honolulu, USA
- Year and Date
  2015-12-15
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K05573
[Presentation] "Super-closed” structure of aspartate aminotransferase unveils the mechanism for the substate-induced transaldimination process2015
- Author(s)
  Hideyuki Hayashi, Takeshi Murakawa, Ikuko Miyahara
- Organizer
  Biocatalysis-2015
- Place of Presentation
  Moscow, Russia
- Year and Date
  2015-06-21
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K05573
[Presentation] 銅アミン酸化酵素のTPQ生成反応と触媒反応における保存性Asn残基の役割2014
- Author(s)
  村川武志，中西将太，元山暁仁，林秀行，谷澤克行，岡島俊英
- Organizer
  日本蛋白質科学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23770127
[Presentation] トレオニン合成酵素の反応機構についての理論的研究:反応特異性決定過程の解明2014
- Author(s)
  庄司光男，氏家謙，田中弥，栢沼愛，梅田宏明，町田康博，村川武志，林秀行
- Organizer
  日本化学会第94春季年会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24570140
[Presentation] 分子動力学法によるトレオニン合成酵素の反応特異性についての理論的解明2013
- Author(s)
  氏家謙，田中弥，花岡恭平，庄司光男，栢沼愛，神谷克政，白石賢二，町田康博，村川武志，林秀行
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24570140
[Presentation] トレオニン合成酵素における反応特異性決定過程の理論解明2013
- Author(s)
  庄司光男，花岡恭平，氏家謙，田中弥，梅田宏明，栢沼愛，神谷克政，白石賢二，町田康博，村川武志，林秀行
- Organizer
  第13回日本蛋白質科学会年会
- Place of Presentation
  鳥取
- Data Source
  KAKENHI-PROJECT-24570140
[Presentation] トレオニン合成酵素における反応特異性についての理論的解明2013
- Author(s)
  庄司光男，氏家謙，田中弥，花岡恭平，梅田宏明，栢沼愛，神谷克政，白石賢二，町田康博，村川武志，林秀行
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24570140
[Presentation] 銅含有アミン酸化酵素の高分解能X線結晶構造解析2012
- Author(s)
  村川武志,岡島俊英,谷澤克行,林秀行
- Organizer
  日本生化学会
- Place of Presentation
  福岡
- Year and Date
  2012-12-15
- Data Source
  KAKENHI-PROJECT-23770127
[Presentation] 銅含有アミン酸化酵素の高分解能X線結晶構造解析2012
- Author(s)
  村川武志，岡島俊英，谷澤克行，林秀行
- Organizer
  酵素補酵素研究会
- Place of Presentation
  名古屋大学（名古屋）
- Data Source
  KAKENHI-PROJECT-23770127
[Presentation] 銅含有アミン酸化酵素の高分解能X線結晶構造解析2012
- Author(s)
  村川武志，岡島俊英，谷澤克行，林秀行
- Organizer
  生化学会近畿支部会
- Place of Presentation
  京都大学（京都）
- Data Source
  KAKENHI-PROJECT-23770127
[Presentation] トレオニン合成酵素におけるリン酸脱離以降の反応機構についての理論的解明2012
- Author(s)
  庄司光男，花岡恭平，近藤大生，田口真彦，栢沼愛，梅田宏明，鴨志田良和，神谷克政，白石賢二，村川武志，林秀行
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  マリンメッセ福岡
- Data Source
  KAKENHI-PROJECT-24570140
[Presentation] 銅含有アミン酸化酵素の高分解能X線結晶構造解析2012
- Author(s)
  村川武志，岡島俊英，谷澤克行，林秀行
- Organizer
  日本生化学会
- Place of Presentation
  福岡国際会議場（福岡）
- Data Source
  KAKENHI-PROJECT-23770127
[Presentation] トレオニン合成酵素の触媒性リン酸イオン結合残基の役割2012
- Author(s)
  町田康博，村川武志，庄司光男，林秀行
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  マリンメッセ福岡
- Data Source
  KAKENHI-PROJECT-24570140
[Presentation] 銅含有アミン酸化酵素の高分解能X線結晶構造解析2012
- Author(s)
  村川武志,岡島俊英,谷澤克行,林秀行
- Organizer
  日本生化学会近畿支部会
- Place of Presentation
  京都
- Year and Date
  2012-05-19
- Data Source
  KAKENHI-PROJECT-23770127
[Presentation] 生成物支援触媒によってもたらされる酵素の反応特異性2011
- Author(s)
  村川武志, 林秀行
- Organizer
  第11回日本蛋白質科学会年会
- Place of Presentation
  吹田
- Year and Date
  2011-06-08
- Data Source
  KAKENHI-PROJECT-21570120
[Presentation] Acid-base chemistry of the catalytic reaction of the bacterial copper amine oxidase2011
- Author(s)
  村川武志, 岡島俊英, 濱口章央, 谷澤克行, 林秀行
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-21570120
[Presentation] Acid-base chemistry of the reductive half reaction of bacterial copper amine oxidase2011
- Author(s)
  Takeshi Murakawa, Toshihide Okajima, Akio Hamaguchi, Katsuyuki Tanizawa, and Hideyuki Hayashi
- Organizer
  日本生化学会
- Place of Presentation
  京都
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-23770127
[Presentation] Acid-base chemistry of the catalytic reaction of the bacterial copper amine oxidase2011
- Author(s)
  Takeshi Murakawa, Toshihide Okajima, Akio Hamaguchi, Katsuyuki Tanizawa, Hideyuki Hayashi
- Organizer
  日本生化学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23770127
[Presentation] Acid-base chemistry of the reductive half reaction of bacterial copper amine oxidase2011
- Author(s)
  Takeshi Murakawa, Toshihide Okajima, Akio Hamaguchi, Katsuyuki Tanizawa, and Hideyuki Hayashi
- Organizer
  ICC-03
- Place of Presentation
  トゥルク,フィンランド
- Year and Date
  2011-07-12
- Data Source
  KAKENHI-PROJECT-23770127
[Presentation] Acid-base chemistry of the catalytic reaction of the bacterial copper amine oxidase2011
- Author(s)
  Takeshi Murakawa, Toshihide Okajima, Akio Hamaguchi, Katsuyuki Tanizawa, Hideyuki Hayashi
- Organizer
  The Third International Conference on Cofactors 03
- Place of Presentation
  フィンランド
- Data Source
  KAKENHI-PROJECT-23770127
[Presentation] Acid-Base Chemistry in the Reductive Half-Reaction of Copper Amine Oxidase from Arthrobacter globiformis2010
- Author(s)
  村川武志
- Organizer
  Gordon Research Conference
- Place of Presentation
  Ventura(USA)
- Data Source
  KAKENHI-PROJECT-19770118
[Presentation] 銅含有アミン酸化酵素の触媒機構:酸化的半反応中間体の立体構造解析2010
- Author(s)
  喜久川政吾, 岡島俊英, 濱口章央, 村川武志, 林秀行, 谷澤克行
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-21570120
[Presentation] トレオニン合成酵素の分光学的および速度論的解析2010
- Author(s)
  村川武志, 林秀行
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-21570120
[Presentation] 銅アミン酸化酵素反応はトパセミキノンラジカル中間体を経由して進行する2009
- Author(s)
  濱口章央, 岡島俊英, 谷澤克行, 村川武志, 林秀行
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2009-10-22
- Data Source
  KAKENHI-PROJECT-21570120
[Presentation] 速度論および構造解析に基づく酵素触媒反応におけるプロトントンネリング機構の解析2009
- Author(s)
  村川武志, 岡島俊英, 谷澤克行, 林秀行
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2009-10-22
- Data Source
  KAKENHI-PROJECT-21570120
[Presentation] 速度論および構造解析に基づく酵素触媒反応におけるプロトントンネリング機構の解析2009
- Author(s)
  村川武志
- Organizer
  日本生化学会
- Place of Presentation
  神戸ポートアイランド(兵庫)
- Year and Date
  2009-10-22
- Data Source
  KAKENHI-PROJECT-19770118
[Presentation] 速度論および構造解析に基づく酵素触媒反応におけるプロトントンネリング機構の解析2009
- Author(s)
  村川武志
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド(兵庫)
- Year and Date
  2009-10-22
- Data Source
  KAKENHI-PROJECT-21570120
[Presentation] Hydrogen Tunneling in Bacterial Copper Amine Oxidase Reaction2008
- Author(s)
  村川武志
- Organizer
  Gordon Research Conference
- Place of Presentation
  Ventura (USA)
- Data Source
  KAKENHI-PROJECT-19770118
[Presentation] 速度論および構造解析に基づく酵素反応触媒反応におけるプロトントンネリング機構の解析2008
- Author(s)
  村川武志
- Organizer
  日本生化学会
- Place of Presentation
  神戸
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-19770118
[Presentation] 銅アミン酸化酵素のTPQ補酵素とその前駆体Tyr残基のコンフォメーション制御の分子機構
- Author(s)
  村川武志，中西将太，元山暁仁，林秀行，谷澤克行，岡島俊英
- Organizer
  日本生化学会
- Place of Presentation
  京都
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-26440037
[Presentation] 銅アミン酸化酵素のTPQ生成反応と触媒反応における保存性Asn残基の役割
- Author(s)
  村川武志，中西将太，元山暁仁，林秀行，谷澤克行，岡島俊英
- Organizer
  日本蛋白質科学会
- Place of Presentation
  横浜
- Year and Date
  2014-06-25 – 2014-06-27
- Data Source
  KAKENHI-PROJECT-26440037
[Presentation] トレオニン合成酵素の触媒過程前半部分の解析
- Author(s)
  林秀行，村川武志，庄司光男
- Organizer
  日本化学会第95春季年会
- Place of Presentation
  船橋
- Year and Date
  2015-03-26 – 2015-03-29
- Data Source
  KAKENHI-PROJECT-24570140
[Presentation] Conformational flexibility of the topa quinone cofactor in copper amine oxidase revealed by site-specific mutagenesis of the neighboring conserved asparagine residue
- Author(s)
  Takeshi Murakawa, Hideyuki Hayashi, Katsuyuki Tanizawa, Toshihide Okajima
- Organizer
  ICC-04
- Place of Presentation
  イタリア，パルマ
- Year and Date
  2014-08-24 – 2014-08-30
- Data Source
  KAKENHI-PROJECT-26440037
[Presentation] トレオニン合成酵素の触媒反応前半部分の反応機構解析
- Author(s)
  町田康博，村川武志，庄司光男，林秀行
- Organizer
  第61回日本生化学会近畿支部例会
- Place of Presentation
  京都
- Year and Date
  2014-05-17 – 2015-05-17
- Data Source
  KAKENHI-PROJECT-24570140

1. HAYASHI Hideyuki (00183913)

# of Collaborated Projects: 6 results

# of Collaborated Products: 37 results
2. 馬場清喜 (00437344)

# of Collaborated Projects: 5 results

# of Collaborated Products: 2 results
3. Shoji Mitsuo (00593550)

# of Collaborated Projects: 3 results

# of Collaborated Products: 17 results
4. Okajima Toshihide (10247968)

# of Collaborated Projects: 3 results

# of Collaborated Products: 25 results
5. 福井健二 (00466038)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 中井忠志 (00333344)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 鈴木守 (40280507)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 栗原和男 (50354890)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 安達基泰 (60293958)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 鈴木陽一 (40432330)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 高橋宏隆 (70432804)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Murakawa Takeshi 村川 武志

MURAKAWA Takeshi 村川 武志

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Analysis of proton transfer in enzymatic reactions based on quantum theoryPrincipal Investigator

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速度論および熱力学的手法を用いた"in crystallo" 酵素反応解析Principal Investigator

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シリアルフェムト秒結晶構造解析に基づく銅含有アミン酸化酵素の触媒機構の解明Principal Investigator

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非凍結結晶を用いた“in crystallo”酵素反応解析Principal Investigator

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シリアルフェムト秒結晶構造解析による銅含有アミン酸化酵素の触媒機構の解明Principal Investigator

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In crystallo thermodynamic analysis of the cofactor conformational change of copper amine oxidasePrincipal Investigator

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X-ray and neutron crystallographic structure of copper amine oxidasePrincipal Investigator

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Murakawa Takeshi 村川武志

MURAKAWA Takeshi 村川武志