Yamamoto Naoki 山本直樹

… Alternative Names

YAMAMOTO Naoki 山本直樹

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Researcher Number	90448283
Other IDs	https://orcid.org/0000-0001-8423-3634
Affiliation (Current)	2024: 山口大学, 教育・学生支援機構, 教授
Affiliation (based on the past Project Information) *help	2020 – 2024: 山口大学, 教育・学生支援機構, 教授 2019: 山口大学, 教育・学生支援機構, 准教授 2015 – 2019: 山口大学, 大学教育機構, 准教授 2010 – 2016: Yamaguchi University, 大学教育機構, 講師 2009: Yamaguchi University, 大学院・医学系研究科, 助教 … More 2008: 山口大学, 大学院・医学系研究科, 医員 2007 – 2008: Yamaguchi University, 医学部・附属病院, 医員 2007 – 2008: 山口大学, 医学部附属病院, 医員 2007: 山口大学, 医学部付属病院, 医員 Less
Review Section/Research Field	Principal Investigator Gastroenterology / Basic Section 53010:Gastroenterology-related Except Principal Investigator Gastroenterology / Basic Section 53010:Gastroenterology-related / General internal medicine (including Psychosomatic medicine) / Basic Section 42020:Veterinary medical science-related / Developmental mechanisms and the body works / Natural medicines / Veterinary medical science
Keywords	Principal Investigator 肝線維化 / 電子顕微鏡 / 再生医療 / 骨髄細胞 / 肝硬変 / EpCAM / 幹細胞 / 肝脂肪化 / 間葉系幹細胞 / 培養骨髄細胞 … More / GFP/CCl4モデル / 免疫電顕 / 骨髄幹細胞 / 肝臓再生 / 発生・分化 / 再生医学 / 移植・再生医療 / 肝臓修復細胞 / MAFLD / iPS細胞 / Adenylate kinase / CXCR4 / 四塩化炭素 / 代謝性脂肪性肝疾患 / アデノシンデアミナーゼ / 脂肪性肝疾患 / 肝線維化抑制 / MMP9 / stem cell / AutoMACS / CCl4モデル / CCL4モデル / 非アルコール性脂肪性肝炎 / GFP/CC14モデル / 非アルコール性肝炎 … More Except Principal Investigator 間葉系幹細胞 / 骨髄細胞 / 肝線維化 / 肝硬変症 / 肝再生 / 肝硬変 / 再生医療 / 肝細胞癌 / メダカ / 鉄キレート剤 / 骨髄間葉系幹細胞 / 肝臓再生 / 肝臓 / ゼブラフィッシュ / 癌 / microRNA / CT enterography / クローン病 / エクソソーム / 再生療法 / 移植・再生医療 / 老化 / 犬 / 肝線維症 / HTVi法 / Maid / NASH / Deferasirox / Deferoxamine / 非アルコール性脂肪性肝炎 / 非アルコール性脂肪肝炎 / 漢方薬 / 細胞・組織 / 移植 / 電子顕微鏡 / 肝発癌 / 再生医学 / 細胞増殖 / 自己骨髄細胞 / 腸管線維化 / 肝脂肪化 / Cross-sectional imaging / 線維性腸管狭窄 / アデニル酸キナーゼ / ミトコンドリア / 代謝 / 鉄キレート / 細胞 / キレート / 鉄 / がん / 骨髄 / 肝臓修復細胞 / マウス / 細胞外小胞 / deferoxamine / deferasirox / 膵癌 / 運動刺激 / 加齢変化 / 抗重力筋 / 踏み台昇運動 / 年齢差 / 性差 / サテライトセル / エキセントリック収縮 / 踏み台昇降運動 / Matrix metalloproteinase / コラゲナーゼ活性 / 酸化ストレス / トランスレーショナルリサーチ / 線維化改善 / 間葉系細胞 / ライブイメージング / マクロファージ / 細胞療法 / 薬剤 / 分子標的薬 / 動物モデル / 血管新生 / 寛解維持療法 / dextran sulfate sodium / 大建中湯 / 潰瘍性大腸炎 / 肝機能検査 / ICGクリアランス / 肝動脈 / 慢性肝炎 / 骨髄間質細胞 / アデニル酸カイネース / サーカデイアンリズム / 脂肪肝 / サーカディアンリズム / 肝障害 / Deferoximine / DEN発癌モデル / DEN肝発癌モデル / Sorafenib / CDAAモデル / 肝臓病 / 遺伝子導入法 / 線維化 / 遺伝子導入 / 肝前癌性病変 / 肝繊維化 / 肝線維化. / 遺伝子治療 / ABMi療法 / 修復再生療法 / FGF / HTVi 法 / 肝臓修復 / TNFR1 KO / Maid KO / Maid KO mice / medaka / 非アルコール脂肪肝炎 / 肝発がん / 薬剤スクリーニング / 高脂肪食 / 進行肝細胞癌 / 肝発癌ラットモデル / 薬理学 / 肝腺維化 / MMP9 / サイトカイン / 発癌 Less

Novel therapeutic strategies to overcome intestinal fibrosis in Crohn's disease
- Principal Investigator
  
  橋本真一
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Yamaguchi University
Establishment of Mass Production Method and Functional Enhancement of Mesenchymal Stem Cells for Liver Regeneration Therapy
- Principal Investigator
  
  藤澤浩一
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  University of Occupational and Environmental Health, Japan
間葉系幹細胞の作用を洗練・集約化した抗線維化microRNA封入脂質ナノ粒子の開発
- Principal Investigator
  
  松本俊彦
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Yamaguchi University
iPS細胞から誘導した間葉系幹細胞由来細胞外小胞によるセルフリー肝臓再生療法の開発
- Principal Investigator
  
  高見太郎
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Yamaguchi University
The cell identification research of bone marrow drived liver repaired cell in the new liver regeneration therapyPrincipal Investigator
- Principal Investigator
  
  山本直樹
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Yamaguchi University
新規骨髄由来肝臓修復細胞による肝臓再生療法の開発
- Principal Investigator
  
  谷健二
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Yamaguchi University
鉄除去により強制的に変化させた代謝を標的とした新規抗癌併用療法の開発
- Principal Investigator
  
  藤澤浩一
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  University of Occupational and Environmental Health, Japan
  Yamaguchi University
線維性腸管狭窄に対するメカニズムの解明と臨床応用への検討
- Principal Investigator
  
  橋本真一
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Yamaguchi University
Development of hybrid therapy using iron chelators and regenerative therapy for advanced hepatocellular carcinoma with decompensated liver cirrhosis
- Principal Investigator
  
  Takami Taro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Yamaguchi University
抗線維化作用増強exosomeを用いた継続型低侵襲肝臓再生療法の開発
- Principal Investigator
  
  松本俊彦
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Yamaguchi University
The development research of liver regeneration therapy used bone marrow drived liver repaired cell
- Principal Investigator
  
  SAKAIDA Isao
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Yamaguchi University
二種類の骨髄由来肝臓修復細胞による効率的な肝臓再生療法の開発Principal Investigator
- Principal Investigator
  
  山本直樹
- Project Period (FY)
  2018 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Yamaguchi University
Development of cell-free liver regeneration therapy with the anticipatory method to culture higher-quality MSCs for liver cirrhosis
- Principal Investigator
  
  TAKAMI Taro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Yamaguchi University
The development of liver regeneration therapy with higher therapeutic effects on liver cirrhosis using a middle-large size liver cirrhosis model.
- Principal Investigator
  
  SAKAIDA Isao
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Yamaguchi University
Age and sex differences in satellite cell activation during step up and down exercise
- Principal Investigator
  
  MIYATA Hirofumi
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Developmental mechanisms and the body works
- Research Institution
  Yamaguchi University
Effects of a novel oral iron chelator on refractory digestive system cancers
- Principal Investigator
  
  YAMASAKI Takahiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Yamaguchi University
The analysis and identification of bome marrow drived liver repair cellPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Naoki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Yamaguchi University
Basic research to develop next generation cell therapy for improvement of liver fibrosis.
- Principal Investigator
  
  TERAI Shuji
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Niigata University
Research and development for liver regeneration therapy with higher-therapeutic effects using the higher-functioning cultured bone marrow mesenchymal stem cells
- Principal Investigator
  
  TAKAMI Taro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Yamaguchi University
Establishment of the bone marrow stromal cell autotransplantation therapy for the chronic liver in dogs
- Principal Investigator
  
  TANI KENJI
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Veterinary medical science
- Research Institution
  Yamaguchi University
Utility of herbal medicine for remission maintenance therapy of ulcerative colitis
- Principal Investigator
  
  HASHIMOTO Shinichi
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Natural medicines
- Research Institution
  Yamaguchi University
Development of Medaka Model for Analysis of Angiogenesis and Kupffer cell
- Principal Investigator
  
  Terai Shuji
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Niigata University
  Yamaguchi University
The analysis of small bone marrow drived liver repair cellPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Naoki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Yamaguchi University
Development of the analytical method of the cancer stem cell using the ATP sensor in the cell
- Principal Investigator
  
  FUJISAWA Koichi
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Yamaguchi University
The development of new combination therapy with deferasirox and sorafenib on advanced hepatocellular carcinama
- Principal Investigator
  
  YAMASAKI Takahiro
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Yamaguchi University
Basic research for chronotherapy focused on liver regeneration andliver steatosis by circadian clock
- Principal Investigator
  
  TERAI Shuji
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Yamaguchi University
The basic research of the development of future generation cell therapy used bone marrow derived liver repaid cell
- Principal Investigator
  
  TERAI Shuji
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Yamaguchi University
Both Herbal medicine Bofu-tsusho-san (TJ-62) and Dai-saiko-to (TJ-8) prevent liver fibrosis and hepatocarcinogenesis in rat liver cirrhosis.
- Principal Investigator
  
  UCHIDA Kouichi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  Yamaguchi University
Development of new gene transfer system for small fish
- Principal Investigator
  
  SAKAIDA Isao
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Yamaguchi University
非アルコール性脂肪性肝炎関連発癌に対する戦略的研究
- Principal Investigator
  
  寺井崇二
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Yamaguchi University
THE ELECTRON MICROSCOPICAL ANALYSIS FOR CELL LINEAGE AND REPAIR FUNCTION OF BONE MARROW CELL IN CIRRHOSIS MICE AND NASH MICEPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Naoki
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Yamaguchi University
Development of a novel therapy using the iron chelator for advanced hepatocellular carcinoma
- Principal Investigator
  
  YAMASAKI Takahiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Yamaguchi University
血管観察トランスジェニックメダカを用いた非アルコール性脂肪性肝炎の病態解析
- Principal Investigator
  
  坂井田功
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Yamaguchi University
Mechanism of fibrolysis and effect on cancer by autologus bone marrow cell infusion therapy for liver cirrhosis
- Principal Investigator
  
  SAKAIDA Isao
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Yamaguchi University
The effect of Herbal medicine Bofu-tsusho-san(TJ-62)and the Crude Drugs with hepatic steatosis
- Principal Investigator
  
  UCHIDA Koichi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  Yamaguchi University
THE ELECTRON MICROSCOPICAL ANALYSIS FOR CELL LINEAGE OF BONE MARROW STEM CELL DIFFERENTIATION IN CIRRHOSIS MICEPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Naoki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Yamaguchi University

[Book] コンセンサス癌治療(最新の肝細胞癌の診断と治療),進行肝癌に対する鉄キレート剤の効果2013
- Author(s)
  山﨑隆弘,山本直樹,寺井崇二,坂井田功, 他
- Publisher
  へるす出版
- Data Source
  KAKENHI-PROJECT-23590978
[Book] コンセンサス癌治療　（最新の肝細胞癌の診断と治療）2013
- Author(s)
  山﨑隆弘、佐伯一成、在津潤一、浦田洋平、高見太郎、山本直樹、寺井崇二、坂井田　功
- Total Pages
  116
- Publisher
  へるす出版
- Data Source
  KAKENHI-PROJECT-23590978
[Journal Article] Adenylate Kinase Isozyme 3 Regulates Mitochondrial Energy Metabolism and Knockout Alters HeLa Cell Metabolism2022
- Author(s)
  Fujisawa Koichi、Wakazaki Maina、Matsuzaki Aya、Matsumoto Toshihiko、Yamamoto Naoki、Noma Takafumi、Takami Taro
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 8 Pages: 4316-4319
- DOI
  10.3390/ijms23084316
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08289, KAKENHI-PROJECT-18K08005, KAKENHI-PROJECT-22K08057, KAKENHI-PROJECT-20H03663, KAKENHI-PROJECT-20K08358
[Journal Article] Involvement of DNA Damage Response via the Ccndbp1-Atm-Chk2 Pathway in Mice with Dextran-Sodium-Sulfate-Induced Colitis2022
- Author(s)
  Horigome R, Kamimura K, Niwa Y, Ogawa K, Mizuno KI, Fujisawa K, Yamamoto N, Takami T, Sugano T, Sakamaki A, Kamimura H, Takamura M, Terai S.
- Journal Title
  
  J Clin Med.
  
  Volume: 11(13) Issue: 13 Pages: 3674-3680
- DOI
  10.3390/jcm11133674
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08005, KAKENHI-PROJECT-20K08289, KAKENHI-PROJECT-20K08326, KAKENHI-PROJECT-22K08057, KAKENHI-PROJECT-20H03663
[Journal Article] Cyclin D1 Binding Protein 1 Responds to DNA Damage through the ATM / CHK2 Pathway2022
- Author(s)
  Niwa Yusuke、Kamimura Kenya、Ogawa K、Oda C、Tanaka Y、Horigome R、Ohtsuka M、Miura H、Fujisawa Koichi、Yamamoto Naoki、Takami Taro、Okuda Shujiro、Ko Masayoshi、Owaki Takashi、Kimura Atsushi、Shibata Osamu、Morita Shinichi、Sakai N、Abe H、Yokoo T、Sakamaki A、Kamimura H、Terai S
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 11 Issue: 3 Pages: 851-851
- DOI
  10.3390/jcm11030851
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08289, KAKENHI-PROJECT-20K17043, KAKENHI-PROJECT-20K08326, KAKENHI-PROJECT-20H03663, KAKENHI-PROJECT-20K08379
[Journal Article] An iron chelation-based combinatorial anticancer therapy comprising deferoxamine and a lactate excretion inhibitor inhibits the proliferation of cancer cells2022
- Author(s)
  Fujisawa Koichi、Takami Taro、Matsumoto Toshihiko、Yamamoto Naoki、Yamasaki Takahiro、Sakaida Isao
- Journal Title
  
  Cancer Metabolism
  
  Volume: 10 Issue: 1 Pages: 8-16
- DOI
  10.1186/s40170-022-00284-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08289, KAKENHI-PROJECT-18K08005, KAKENHI-PROJECT-22K08057, KAKENHI-PROJECT-20H03663, KAKENHI-PROJECT-20K08358
[Journal Article] Effect of drug-eluting bead transarterial chemoembolization loaded with cisplatin on normal dogs2022
- Author(s)
  Nakasumi K, Yamamoto N, Takami T, Itoh H, Itamoto K, Horikirizono H, Iseri T, Nakaichi M, Nemoto Y, Sunahara H, Tani K.
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: 84 Issue: 1 Pages: 114-120
- DOI
  10.1292/jvms.21-0396
- NAID
  130008141140
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08005
[Journal Article] Comparison of two primer-probe sets of Fusobacterium nucleatum using droplet digital polymerase chain reaction for the detection of colorectal neoplasia from faecal samples2022
- Author(s)
  Yamaoka Y, Sasai M, Suehiro Y, Hashimoto S, Goto A, Yamamoto N, Suzuki N, Higaki S, Fujii I, Suzuki C, Matsumoto T, Hoshida T, Koga M, Tsutsumi T, Lim LA, Matsubara Y, Tomochika S, Yoshida S, Hazama S, Yotsuyanagi H, Nagano H, Sakaida I, Takami T, Yamasaki T.
- Journal Title
  
  Ann Clin Biochem.
  
  Volume: 59(6) Issue: 6 Pages: 396-403
- DOI
  10.1177/00045632221115559
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03663
[Journal Article] Evaluation of the Effects of Microgravity on Activated Primary Human Hepatic Stellate Cells2022
- Author(s)
  Fujisawa K, Nishimura Y, Sakuragi A, Duponselle J, Matsumoto T, Yamamoto N, Murata T, Sakaida I, Takami T.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 23(13) Issue: 13 Pages: 7429-7435
- DOI
  10.3390/ijms23137429
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08005, KAKENHI-PROJECT-20K08289, KAKENHI-PROJECT-22K08057, KAKENHI-PROJECT-20H03663, KAKENHI-PROJECT-20K08358
[Journal Article] Establishment of an Adult Medaka Fatty Liver Model by Administration of a Gubra-Amylin-Nonalcoholic Steatohepatitis Diet Containing High Levels of Palmitic Acid and Fructose2021
- Author(s)
  Fujisawa K, Takami T, Okubo S, Nishimura Y, Yamada Y, Kondo K, Matsumoto T, Yamamoto N, Sakaida I.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 22(18) Issue: 18 Pages: 9931-9941
- DOI
  10.3390/ijms22189931
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08005, KAKENHI-PROJECT-20K08289, KAKENHI-PROJECT-20K08358, KAKENHI-PROJECT-20H03663
[Journal Article] Seasonal variations in photoperiod affect hepatic metabolism of medaka ( Oryzias latipes )2021
- Author(s)
  Fujisawa Koichi、Takami Taro、Shintani Haruko、Sasai Nanami、Matsumoto Toshihiko、Yamamoto Naoki、Sakaida Isao
- Journal Title
  
  FEBS Open Bio
  
  Volume: 11 Issue: 4 Pages: 1029-1040
- DOI
  10.1002/2211-5463.13095
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15815, KAKENHI-PROJECT-18K08005, KAKENHI-PROJECT-20K08289, KAKENHI-PROJECT-20H03663
[Journal Article] Metabolic Alterations in Spheroid-Cultured Hepatic Stellate Cells.2020
- Author(s)
  Fujisawa K, Takami T, Sasai N, Matsumoto T, Yamamoto N, Sakaida I.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 21(10) Issue: 10 Pages: 3451-3455
- DOI
  10.3390/ijms21103451
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08005, KAKENHI-PROJECT-20K08289, KAKENHI-PROJECT-20K08358, KAKENHI-PROJECT-18K15815, KAKENHI-PROJECT-20H03663
[Journal Article] Bone marrow-derived humoral factors suppress oxidative phosphorylation, upregulate TSG-6, and improve therapeutic effects on liver injury of mesenchymal stem cells2020
- Author(s)
  Miyaji Takashi、Takami Taro、Fujisawa Koichi、Matsumoto Toshihiko、Yamamoto Naoki、Sakaida Isao
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 66 Issue: 3 Pages: 213-223
- DOI
  10.3164/jcbn.19-125
- NAID
  130007839286
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15815, KAKENHI-PROJECT-17H04162, KAKENHI-PROJECT-17K09428, KAKENHI-PROJECT-18K08005, KAKENHI-PROJECT-20K08358
[Journal Article] Invasion inhibition in pancreatic cancer using the oral iron chelating agent deferasirox2020
- Author(s)
  Amano Shogo、Kaino Seiji、Shinoda Shuhei、Harima Hirofumi、Matsumoto Toshihiko、Fujisawa Koichi、Takami Taro、Yamamoto Naoki、Yamasaki Takahiro、Sakaida Isao
- Journal Title
  
  BMC Cancer
  
  Volume: 20 Issue: 1 Pages: 681-681
- DOI
  10.1186/s12885-020-07167-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08332, KAKENHI-PROJECT-20K08358
[Journal Article] Mesenchymal Stem Cells Induce a Fibrolytic Phenotype By Regulating mmu-miR-6769b-5p Expression in Macrophages.2020
- Author(s)
  Nishi M, Matsumoto T, Fujisawa K, Suehiro Y, Takami T, Yamamoto N, Yamasaki T, Sakaida I.
- Journal Title
  
  Stem Cells Dev.
  
  Volume: 29(22) Issue: 22 Pages: 1457-1466
- DOI
  10.1089/scd.2020.0123
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08005, KAKENHI-PROJECT-20K08332, KAKENHI-PROJECT-20H03663
[Journal Article] Dantrolene prevents hepatic steatosis by reducing cytoplasmic Ca 2+ level and ER stress2020
- Author(s)
  Tamitani M, Yamamoto T, Yamamoto N, Fujisawa K, Tanaka S, Nakamura Y, Uchinoumi H, Oda T, Okuda S, Takami T, Kobayashi S, Sakaida I, Yano M.
- Journal Title
  
  Biochem Biophys Rep.
  
  Volume: 23:100787. Pages: 100787-100793
- DOI
  10.1016/j.bbrep.2020.100787
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08005, KAKENHI-PROJECT-18K08039, KAKENHI-PROJECT-18K08076, KAKENHI-PROJECT-18K08108, KAKENHI-PROJECT-20H03677, KAKENHI-PROJECT-20H03663
[Journal Article] Trans-portal hepatic infusion of cultured bone marrow-derived mesenchymal stem cells in a steatohepatitis murine model2020
- Author(s)
  Sasaki R, Takami T, Fujisawa K, Matsumoto T, Ishikawa T, Yamamoto N, Sakaida I.
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 67 Issue: 3 Pages: 274-282
- DOI
  10.3164/jcbn.20-88
- NAID
  130007934155
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08005, KAKENHI-PROJECT-20K08358, KAKENHI-PROJECT-17K10441, KAKENHI-PROJECT-20H03663
[Journal Article] Bone marrow-derived humoral factors suppress oxidative phosphorylation, upregulate TSG-6, and improve therapeutic effects on liver injury of mesenchymal stem cells2020
- Author(s)
  Miyaji T, Takami T, Fujisawa K, Matsumoto T, Yamamoto N, Sakaida I.
- Journal Title
  
  J Clin Biochem Nutr.
  
  Volume: 66(3) Pages: 213-223
- NAID
  130007839286
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03663
[Journal Article] Evaluation of the Effects of Cultured Bone Marrow Mesenchymal Stem Cell Infusion on Hepatocarcinogenesis in Hepatocarcinogenic Mice With Liver Cirrhosis.2019
- Author(s)
  Matsuura K, Takami T, Maeda M, Hisanaga T, Fujisawa K, Saeki I, Matsumoto T, Hidaka I, Yamamoto N, Sakaida I.
- Journal Title
  
  Transplant Proc.
  
  Volume: 51(3) Issue: 3 Pages: 925-935
- DOI
  10.1016/j.transproceed.2019.03.011
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05287, KAKENHI-PROJECT-18K08005, KAKENHI-PROJECT-17H04162, KAKENHI-PROJECT-17K09428
[Journal Article] Liver regeneration therapy through the hepatic artery-infusion of cultured bone marrow cells in a canine liver fibrosis model.2019
- Author(s)
  Nishimura T, Takami T, Sasaki R, Aibe Y, Matsuda T, Fujisawa K, Matsumoto T, Yamamoto N, Tani K, Taura Y, Sakaida I.
- Journal Title
  
  PLoS One.
  
  Volume: 14(1) Issue: 1 Pages: 234-244
- DOI
  10.1371/journal.pone.0210588
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09428, KAKENHI-PROJECT-16H05287, KAKENHI-PROJECT-17H04162, KAKENHI-PROJECT-18K08005, KAKENHI-PROJECT-18K15815
[Journal Article] Usefulness of adult medaka fish as a model for the evaluation of alcoholic fatty liver.2019
- Author(s)
  Fujisawa K, Takami T, Nagatomo T, Fukui Y, Hoshida H, Saeki I, Matsumoto T, Hidaka I, Yamamoto N, Sakaida I.
- Journal Title
  
  Alcohol.
  
  Volume: 77 Pages: 147-154
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08005
[Journal Article] NUPR1 acts as a pro-survival factor in human bone marrow-derived mesenchymal stem cells and is induced by the hypoxia mimetic reagent deferoxamine.2019
- Author(s)
  Matsunaga K, Fujisawa K, Takami T, Burganova G, Sasai N, Matsumoto T, Yamamoto N, Sakaida I.
- Journal Title
  
  J Clin Biochem Nutr.
  
  Volume: 64(3) Pages: 209-216
- NAID
  130007641429
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08005
[Journal Article] Usefulness of Adult Medaka Fish as a Model for the Evaluation of Alcoholic Fatty Liver.2019
- Author(s)
  Fujisawa K, Takami T, Nagatomo T, Fukui Y, Hoshida H, Saeki I, Matsumoto T, Hidaka I, Yamamoto N, Sakaida I.
- Journal Title
  
  Alcohol.
  
  Volume: 77 Pages: 147-154
- DOI
  10.1016/j.alcohol.2019.01.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09428, KAKENHI-PROJECT-16K19823, KAKENHI-PROJECT-16H05287, KAKENHI-PROJECT-17H04162, KAKENHI-PROJECT-18K15815
[Journal Article] NUPR1 acts as a pro-survival factor in human bone marrow-derived mesenchymal stem cells and is induced by the hypoxia mimetic reagent deferoxamine2019
- Author(s)
  Matsunaga Kazuhito、Fujisawa Koichi、Takami Taro、Burganova Guzel、Sasai Nanami、Matsumoto Toshihiko、Yamamoto Naoki、Sakaida Isao
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 64 Issue: 3 Pages: 209-216
- DOI
  10.3164/jcbn.18-112
- NAID
  130007641429
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15815, KAKENHI-PROJECT-17K09428
[Journal Article] Evaluation of the effects of ascorbic acid on metabolism of human mesenchymal stem cells.2018
- Author(s)
  Fujisawa K, Hara K, Takami T, Okada S, Matsumoto T, Yamamoto N, Sakaida I.
- Journal Title
  
  Stem Cell Res Ther.
  
  Volume: 9(1) Issue: 1 Pages: 93-93
- DOI
  10.1186/s13287-018-0825-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09428, KAKENHI-PROJECT-18K08005, KAKENHI-PROJECT-18K15815, KAKENHI-PROJECT-16H05287, KAKENHI-PROJECT-17H04162
[Journal Article] Assessment of high-fat-diet-induced fatty liver in medaka.2018
- Author(s)
  Fujisawa K, Takami T, Fukui Y, Nagatomo T, Saeki I, Matsumoto T, Hidaka I, Yamamoto N, Okamoto T, Furutani-Seiki M, Sakaida I
- Journal Title
  
  Biol Open.
  
  Volume: 7(11) Pages: 341-347
- DOI
  10.1242/bio.031534
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09428, KAKENHI-PROJECT-18K08005, KAKENHI-PROJECT-16K19823, KAKENHI-PROJECT-18K15815, KAKENHI-PROJECT-17H04162
[Journal Article] Deferasirox, an oral iron chelator, with gemcitabine synergistically inhibits pancreatic cancer cell growth in vitro and in vivo.2018
- Author(s)
  Shinoda S, Kaino S, Amano S, Harima H, Matsumoto T, Fujisawa K, Takami T, Yamamoto N, Yamasaki T, Sakaida I.
- Journal Title
  
  Oncotarget.
  
  Volume: 9(47) Issue: 47 Pages: 28434-28444
- DOI
  10.18632/oncotarget.25421
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09428, KAKENHI-PROJECT-18K08005, KAKENHI-PROJECT-18K15815, KAKENHI-PROJECT-16H05287, KAKENHI-PROJECT-17H04162
[Journal Article] Analysis of Metabolomic Changes in Mesenchymal Stem Cells on Treatment with Desferrioxamine as a Hypoxia Mimetic Compared to Hypoxic Conditions.2018
- Author(s)
  Fujisawa K, Takami T, Okada S, Hara K, Matsumoto T, Yamamoto N, Yamasaki T, Sakaida I.
- Journal Title
  
  Stem Cells.
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04162
[Journal Article] Treatment strategies for advanced hepatocellular carcinoma: Sorafenib vs hepatic arterial infusion chemotherapy.2018
- Author(s)
  Saeki I, Yamasaki T, Maeda M, Hisanaga T, Iwamoto T, Fujisawa K, Matsumoto T, Hidaka I, Marumoto Y, Ishikawa T, Yamamoto N, Suehiro Y, Takami T, Sakaida I.
- Journal Title
  
  World J Hepatol.
  
  Volume: 10(9) Issue: 9 Pages: 571-584
- DOI
  10.4254/wjh.v10.i9.571
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09428, KAKENHI-PROJECT-18K08005, KAKENHI-PROJECT-18K15815, KAKENHI-PROJECT-16H05287, KAKENHI-PROJECT-17H04162
[Journal Article] Analysis of Metabolomic Changes in Mesenchymal Stem Cells on Treatment with Desferrioxamine as a Hypoxia Mimetic Compared to Hypoxic Conditions.2018
- Author(s)
  Fujisawa K, Takami T, Okada S, Hara K, Matsumoto T, Yamamoto N, Yamasaki T, Sakaida I.
- Journal Title
  
  Stem Cells
  
  Volume: 印刷中 Issue: 8 Pages: 1226-1236
- DOI
  10.1002/stem.2826
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09428, KAKENHI-PROJECT-16K21193, KAKENHI-PROJECT-18K08005, KAKENHI-PROJECT-18K15815, KAKENHI-PROJECT-16H05287
[Journal Article] Effectiveness of tolvaptan monotherapy and low-dose furosemide/tolvaptan combination therapy for hepatoprotection and diuresis in a rat cirrhotic model2017
- Author(s)
  Tanabe N, Takami T, Fujisawa K, Matsumoto T, Yamamoto N, Sakaida I.
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 61 Issue: 1 Pages: 53-59
- DOI
  10.3164/jcbn.16-122
- NAID
  130006847656
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05287, KAKENHI-PROJECT-15K09005, KAKENHI-PROJECT-16K21193
[Journal Article] 動注化学療法の新たな工夫－deferoxamineの効果－2017
- Author(s)
  山﨑隆弘, 佐伯一成, 藤澤浩一, 松本俊彦, 末廣　寛, 山本直樹, 高見太郎, 坂井田　功
- Journal Title
  
  肝胆膵
  
  Volume: 75(2) Pages: 374-382
- Data Source
  KAKENHI-PROJECT-16H05287
[Journal Article] Protective Effect of Daikenchuto on Dextran Sulfate Sodium-Induced Colitis in Mice2017
- Author(s)
  Takaharu Matsunaga, Shinichi Hashimoto, Naoki Yamamoto, Ryo Kawasato, Tomohiro Shirasawa, Atsushi Goto, Koichi Fujisawa, Taro Takami, Takeshi Okamoto, Jun Nishikawa, and Isao Sakaida
- Journal Title
  
  Gastroenterology Research and Practice
  
  Volume: 1298263 Pages: 1298263-1298263
- DOI
  10.1155/2017/1298263
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25460123, KAKENHI-PROJECT-16H05287
[Journal Article] Evaluating effects of L-carnitine on human bone-marrow-derived mesenchymal stem cells.2017
- Author(s)
  Fujisawa K, Takami T (Corresponding), Fukui Y, Quintanilha LF, Matsumoto T, Yamamoto N, Sakaida I.
- Journal Title
  
  Cell Tissue Res
  
  Volume: 368(2) Issue: 2 Pages: 301-310
- DOI
  10.1007/s00441-017-2569-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09428, KAKENHI-PROJECT-16H05287, KAKENHI-PROJECT-15K09005, KAKENHI-PROJECT-16K21193
[Journal Article] A canine liver fibrosis model to develop a therapy for liver cirrhosis using cultured bone marrow-derived cells.2017
- Author(s)
  Matsuda T, Takami T, Sasaki R, Nishimura T, Aibe Y, Paredes BD, Quintanilha LF, Matsumoto T, Ishikawa T, Yamamoto N, Tani K, Terai S, Taura Y, Sakaida I.
- Journal Title
  
  Hepatology Communications
  
  Volume: 1 Issue: 7 Pages: 691-703
- DOI
  10.1002/hep4.1071
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09428, KAKENHI-PROJECT-16H05287, KAKENHI-PROJECT-17H04162, KAKENHI-PROJECT-15K09005, KAKENHI-PROJECT-16K21193
[Journal Article] Profiling of the circadian metabolome in thioacetamide-induced liver cirrhosis in mice.2017
- Author(s)
  Fujisawa K, Takami T, Matsumoto T, Yamamoto N, Sakaida I.
- Journal Title
  
  Hepatol Commun.
  
  Volume: 1(7) Issue: 7 Pages: 704-718
- DOI
  10.1002/hep4.1075
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05287, KAKENHI-PROJECT-17H04162, KAKENHI-PROJECT-15K09005
[Journal Article] Evaluation of the effects of L-carnitine on medaka (Oryzias latipes) fatty liver.2017
- Author(s)
  Fujisawa K, Takami T, Matsuzaki A, Matsumoto T, Yamamoto N, Terai S, Sakaida I.
- Journal Title
  
  Sci Rep.
  
  Volume: 7(1) Issue: 1 Pages: 2749-2749
- DOI
  10.1038/s41598-017-02924-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05287, KAKENHI-PROJECT-15K09005, KAKENHI-PROJECT-16K21193
[Journal Article] Modulation of anti-cancer drug sensitivity through the regulation of mitochondrial activity by adenylate kinase 4.2016
- Author(s)
  Fujisawa K, Terai S, Takami T, Yamamoto N, Yamasaki T, Matsumoto T, Yamaguchi K, Owada Y, Nishina H, Noma T, Sakaida I.
- Journal Title
  
  J Exp Clin Cancer Res.
  
  Volume: - Issue: 1 Pages: 48-48
- DOI
  10.1186/s13046-016-0322-2
- NAID
  120006937642
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461009, KAKENHI-PLANNED-26114005, KAKENHI-PROJECT-16H05287, KAKENHI-PROJECT-26293012, KAKENHI-PROJECT-15K09005
[Journal Article] Effects of an oral iron chelator, deferasirox, on advanced hepatocellular carcinoma2016
- Author(s)
  Saeki I, Yamamoto N, Yamasaki T(corresponding author), Takami T, Maeda M, Fujisawa K, Iwamoto T, Matsumoto T, Hidaka I, Ishikawa T, Uchida k, Tani K, Sakaida I
- Journal Title
  
  World J Gastroenterol.
  
  Volume: 22(40) Issue: 40 Pages: 8967-77
- DOI
  10.3748/wjg.v22.i40.8967
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05287
[Journal Article] Effects of an oral iron chelator, deferasirox, on advanced hepatocellular carcinoma.2016
- Author(s)
  Yamamoto N, Saeki I, Yamasaki T, Takami T, Maeda M, Fujisawa K, Iwamoto T, Matsumoto T, Hidaka I, Ishikawa T, Uchida K, Tani K, Sakaida I.
- Journal Title
  
  World J Gastroenterol.
  
  Volume: 22(40) Pages: 8967-8977
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K09005
[Journal Article] Deferasirox, an oral iron chelator, prevents hepatocarcinogenesis and adverse effects of sorafenib2016
- Author(s)
  Yamamoto N, Yamasaki T,Takami T,Matsumoto T,Fujisawa K,Saeki I,Uchida K, Terai S, Sakaida I,
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: in press
- NAID
  130005149374
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K09005
[Journal Article] Deferasirox, an oral iron chelator, prevents hepatocarcinogenesis and adverse effects of sorafenib.2016
- Author(s)
  Yamamoto N, Yamasaki T, Takami T, Uchida K, Fujisawa K, Matsumoto T, Saeki I, Terai S, Sakaida I.
- Journal Title
  
  J Clin Biochem Nutr.
  
  Volume: May;58(3): Pages: 202-9
- NAID
  130005149374
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293175
[Journal Article] Deferasirox, a novel oral iron chelator, shows antiproliferative activity against pancreatic cancer in vitro and in vivo.2016
- Author(s)
  Harima H, Kaino S, Takami T, Shinoda S, Matsumoto T, Fujisawa K, Yamamoto N, Yamasaki T, Sakaida I.
- Journal Title
  
  BMC Cancer.
  
  Volume: 16 Issue: 1 Pages: 702-702
- DOI
  10.1186/s12885-016-2744-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05287, KAKENHI-PROJECT-15K09005
[Journal Article] Deferasirox, an oral iron chelator, prevents hepatocarcinogenesis and adverse effects of sorafenib2016
- Author(s)
  Yamamoto N, Yamasaki T, Takami T, Uchida K, Fujisawa K, Matsumoto T, Saeki I, Terai S, Sakaida I.
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 58 Issue: 3 Pages: 202-209
- DOI
  10.3164/jcbn.15-127
- NAID
  130005149374
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05287, KAKENHI-PROJECT-15K09005
[Journal Article] Endoscopic Removal of Ingested Dentures and Dental Instruments: A Retrospective Analysis.2016
- Author(s)
  Mizuno KI, Takahashi K, Tominaga K, Nishigaki Y, Sato H, Ikarashi S, Hayashi K, Yamamoto T, Honda Y, Hashimoto S, Kamimura K, Takeuchi M, Yokoyama J, Sato Y, Kobayashi M, Terai S:
- Journal Title
  
  Gastroenterology research and practice.
  
  Volume: 3537147 Pages: 1-5
- DOI
  10.1155/2016/3537147
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293175
[Journal Article] Evidence for a Role of the Transcriptional Regulator Maid in Tumorigenesis and Aging.2015
- Author(s)
  Fujisawa K, Terai S, Matsumoto T, Takami T, Yamamoto N, Nishina H, Furutani-Seiki M, Sakaida I.
- Journal Title
  
  PLoS One
  
  Volume: 10（６） Issue: 6 Pages: e0129950-e0129950
- DOI
  10.1371/journal.pone.0129950
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09005, KAKENHI-PROJECT-26461009, KAKENHI-PROJECT-25670370, KAKENHI-PROJECT-26293175
[Journal Article] A new therapeutic assessment score for advanced hepatocellular carcinoma patients receiving hepatic arterial infusion chemotherapy.2015
- Author(s)
  Saeki I, Yamasaki T, Tanabe N, Iwamoto T, Matsumoto T, Urata Y, Hidaka I, Ishikawa T, Takami T, Yamamoto N, Uchida K, Terai S, Sakaida I.
- Journal Title
  
  PLoS One.
  
  Volume: 10(5) Issue: 5 Pages: e0126649-e0126649
- DOI
  10.1371/journal.pone.0126649
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K09005, KAKENHI-PROJECT-26461009
[Journal Article] Circadian variations in the liver metabolites of medaka (Oryzias latipes).2015
- Author(s)
  Fujisawa K, Takami T, Kimoto Y, Matsumoto T, Yamamoto N, Terai S, Sakaida I.
- Journal Title
  
  Sci Rep.
  
  Volume: - Issue: 1 Pages: 20916-20916
- DOI
  10.1038/srep20916
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461009, KAKENHI-PROJECT-25670370, KAKENHI-PROJECT-26293175, KAKENHI-PROJECT-15K09005
[Journal Article] Status and prospects of liver cirrhosis treatment by using bone marrow-derived cells and mesenchymal cells.2014
- Author(s)
  Terai S, Takami T, Yamamoto N, Fujisawa K, Ishikawa T, Urata Y, Tanimoto H, Iwamoto T, Mizunaga Y, Matsuda T, Oono T, Marumoto M, Burganova G, Fernando Quintanilha L, Hidaka I, Marumoto Y, Saeki I, Uchida K, Yamasaki T, Tani K, Taura Y, Fujii Y, Nishina H, Okita K, Sakaida I.
- Journal Title
  
  Tissue Eng Part B Rev
  
  Volume: 20(3) Issue: 3 Pages: 206-210
- DOI
  10.1089/ten.teb.2013.0527
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24590978, KAKENHI-PROJECT-26293012, KAKENHI-PROJECT-26293175, KAKENHI-PROJECT-26461009
[Journal Article] Enhanced survival of mice infused with bone marrow-derived as compared with adipose-derived mesenchymal stem cells.2014
- Author(s)
  Shiratsuki S, Terai S, Murata Y, Takami T, Yamamoto N, Fujisawa K, Burganova G, Quintanilha LF, Sakaida I.
- Journal Title
  
  Hepatol Res
  
  Volume: - Issue: 13 Pages: 1353-1359
- DOI
  10.1111/hepr.12507
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590978, KAKENHI-PROJECT-26461009, KAKENHI-PROJECT-26860974, KAKENHI-PROJECT-15K09005
[Journal Article] Bone-marrow-derived cells cultured in serum-free medium reduce liver fibrosis and improve liver function in carbon-tetrachloride-treated cirrhotic mice.2013
- Author(s)
  Iwamoto T, Terai S, Hisanaga T, Takami T, Yamamoto N, Watanabe S, Sakaida I.
- Journal Title
  
  Cell Tissue Res.
  
  Volume: 351(3) Issue: 3 Pages: 487-95
- DOI
  10.1007/s00441-012-1528-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590978, KAKENHI-PROJECT-24790703
[Journal Article] Canine mesenchymal stem cells show antioxidant properties against thioacetamide-induced liver injury in vitro and in vivo.2013
- Author(s)
  Quintanilha LF, Takami T, Hirose Y, Fujisawa K, Murata Y, Yamamoto N, Goldenberg RC, Terai S, Sakaida I.
- Journal Title
  
  Hepatol Res.
  
  Volume: - Issue: 10
- DOI
  10.1111/hepr.12204
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590978, KAKENHI-PROJECT-24790703, KAKENHI-PROJECT-26461009
[Journal Article] Improvement of liver fibrosis by infusion of cultured cells derived from human bone marrow.2013
- Author(s)
  Tanimoto H, Terai S, Taro T, Murata Y, Fujisawa K, Yamamoto N, Sakaida I.
- Journal Title
  
  Cell Tissue Res.
  
  Volume: 354(3) Issue: 3 Pages: 717-28
- DOI
  10.1007/s00441-013-1727-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590978, KAKENHI-PROJECT-24790703
[Journal Article] Bortezomib induces tumor-specific cell death and growth inhibition in hepatocellular carcinoma and improves liver fibrosis.2013
- Author(s)
  Saeki I, Terai S, Fujisawa K, Takami T, Yamamoto N, Matsumoto T, Hirose Y, Murata Y, Yamasaki T, Sakaida I.
- Journal Title
  
  J Gastroenterol.
  
  Volume: 48(6) Issue: 6 Pages: 738-50
- DOI
  10.1007/s00535-012-0675-z
- NAID
  10031184064
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590978, KAKENHI-PROJECT-24590978
[Journal Article] Serum transferrin as a predictor of prognosis for hepatic arterial infusion chemotherapy in advanced hepatocellular carcinoma.2013
- Author(s)
  Zaitu J
- Journal Title
  
  Hepatol Res
  
  Volume: Apr 22 Issue: 5 Pages: 481-90
- DOI
  10.1111/hepr.12141
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590978, KAKENHI-PROJECT-23591821, KAKENHI-PROJECT-24590978, KAKENHI-PROJECT-26461009
[Journal Article] Splenectomy enhances the anti-fibrotic effect of bone marrow cell infusion and improves liver function in cirrhotic mice and patients2012
- Author(s)
  Iwamoto T, Terai S, Mizunaga Y, Yamamoto N, Omori K, Uchida K, Yamasaki T, Fujii Y, Nishina H, Sakaida I
- Journal Title
  
  J Gastroenterol
  
  Volume: 47(3) Pages: 300-312
- NAID
  10030560153
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390150
[Journal Article] Therapeutic potential of canine bone marrow stromal cells (BMSCs) in the carbon tetrachloride (CCl4) induced chronic liver dysfunction mouse model2012
- Author(s)
  Haraguchi T, Tani K, Takagishi R, Oda Y, Itamoto K, Yamamoto N, Terai S, Sakaida I, Nakazawa H, Taura Y
- Journal Title
  
  J Vet Med Sci
  
  Volume: 74(5 Pages: 607-611
- NAID
  130001879886
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390150
[Journal Article] Bone-marrow-derived cells cultured in serum-free medium reduce liver fibrosis and improve liver function in carbon-tetrachloride-treated cirrhotic mice2012
- Author(s)
  Iwamoto T, Terai S, Hisanaga T, Takami T,Yamamoto N, Watanabe S, Sakaida I
- Journal Title
  
  Cell Tissue Res
  
  Volume: 351(3) Pages: 487-495
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390150
[Journal Article] Matrix metalloproteinases (MMPs) activity in cultured canine bone marrow stromal cells (BMSCs)2012
- Author(s)
  Haraguchi T, Tani K, Koga M, Oda Y, Itamoto K, Yamamoto N, Terai S, Sakaida I, Nakazawa H, Taura Y
- Journal Title
  
  J Vet Med Sci
  
  Volume: 74(5) Pages: 633-636
- NAID
  130001410433
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390150
[Journal Article] Bortezomib induces tumor-specific cell death and growth inhibition in hepatocellular carcinoma and improves liver fibrosis2012
- Author(s)
  Saeki I, Terai S, Fujisawa K, Takami T, Yamamoto N, Matsumoto T, Hirose Y, Murata Y, Yamasaki T, Sakaida I
- Journal Title
  
  J Gastroenterol
  
  Volume: 26 Pages: 1-13
- NAID
  10031184064
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390150
[Journal Article] Timeline for development of autologous bone marrow infusion (ABMi) therapy and perspective for future stem cell therapy2012
- Author(s)
  Terai S, Tanimoto H, Maeda M, Zaitsu J, Hisanaga T, Iwamoto T, Fujisawa K, Mizunaga Y, Matsumoto T, Urata Y, Marumoto Y, Hidaka I, Ishikawa T, Yokoyama Y, Aoyama K, Tsuchiya M, Takami T, Omori K, Yamamoto N, Segawa M, Uchida K, Yamasaki T, Okita K, Sakaida I
- Journal Title
  
  J Gastroenterol
  
  Volume: 47(5) Pages: 491-497
- NAID
  10030650365
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390150
[Journal Article] Granulocyte colony-stimulating factor and interleukin-1β are important cytokines in repair of the cirrhotic liver after bone marrow cell infusion: comparison of humans and model mice2012
- Author(s)
  Mizunaga Y, Terai S, Yamamoto N, Uchida K, Yamasaki T, Nishina H, Fujita Y, Shinoda K, Hamamoto Y, Sakaida I
- Journal Title
  
  Cell Transplant
  
  Volume: 21(11) Pages: 2363-2375
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390150
[Journal Article] Senescence marker protein 30(SMP30)/ regucalcin(RGN) expression decreases with aging, acute liver injuries and tumors in zebrafish2011
- Author(s)
  Fujisawa K, Terai S, Hirose Y, Takami T, Yamamoto N, Sakaida I.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 414 Pages: 331-336
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659148
[Journal Article] Senescence　marker protein 30 (SMP30)/regucalcin (RGN) expression decreases with aging, acute　liver injuries and tumors in zebrafish.2011
- Author(s)
  Fujisawa K, Terai S, Hirose Y, Takami T, Yamamoto N, Sakaida I.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 414 Pages: 331-336
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659398
[Journal Article] TNFR1-mediated signaling is important to induce the improvement of liver fibrosis by bone marrow cell infusion2011
- Author(s)
  Hisanaga T, Terai S, Iwamoto T, Takami T, Yamamoto N, Murata T, Matsuyama T, Nishina H, Sakaida I
- Journal Title
  
  Cell Tissue Res
  
  Volume: 346(1) Pages: 79-88
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390150
[Journal Article] Senescence marker protein 30 (SMP30)/regucalcin (RGN) expression decreases with aging, acute liver injuries and tumors in zebrafish2011
- Author(s)
  Fujisawa K
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 414(2) Issue: 2 Pages: 331-336
- DOI
  10.1016/j.bbrc.2011.09.067
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390150, KAKENHI-PROJECT-22659148
[Journal Article] Splenectomy reduces fibrosis and preneoplastic lesions with increased triglycerides and essential fatty acids in rat liver cirrhosis induced by a choline-deficient L-amino acid-defined diet.2010
- Author(s)
  Oishi T, Terai S, Iwamoto T, Takami T, Yamamoto N, Sakaida I.
- Journal Title
  
  Hepatol Res. in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790668
[Journal Article] Medaka as a model for human nonalcoholic steatohepatitis.2010
- Author(s)
  Matsumoto T, Terai S, Oishi T, Kuwashiro S, Fujisawa K, Yamamoto N, Fujita Y, Hamamoto Y, Furutani-Seiki M, Nishina H, Sakaida I.
- Journal Title
  
  Dis Model Mech. 3(7-8)
  
  Pages: 431-440
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790668
[Journal Article] Continuos intravenous infusion of atrial natriuretic peptide (ANP) prevented liver fibrosis in rat.2009
- Author(s)
  Ishigaki N, Yamamoto N, Jin H, Uchida K, Terai S, Sakaida I.
- Journal Title
  
  Biochem Biophys Res Commun. 16;378(3)
  
  Pages: 354-359
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790668
[Journal Article] Continuos intravenous infusion of atrial natriuretic peptide (ANP) prevented liver fibrosis in rat.2009
- Author(s)
  Ishigaki N, Yamamoto N, Jin H, Uchida K, Terai S, Sakaida I
- Journal Title
  
  378(3)
  
  Pages: 354-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390199
[Journal Article] Sakaida I Continuos intravenous infusion of atrial natriuretic peptide (ANP)2009
- Author(s)
  Ishigaki N, Yamamoto N, Jin H, Uchida K, Terai S
- Journal Title
  
  prevented liver fibrosis in rat 378(3)
  
  Pages: 354-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790486
[Journal Article] Continuous high expression of XBP1 and GRP78 is important for the survival of bone marrow cells in CCl4-treated cirrhotic liver.2008
- Author(s)
  Marumoto Y, Terai S, Urata Y, Matsumoto T, Mizunaga Y, Yamamoto N, Jin H, Fujisawa K, Murata T, Shinoda K, Nishina H, Sakaida I
- Journal Title
  
  Biochem Biophys Res Commun 367(3)
  
  Pages: 546-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390199
[Journal Article] Continuous high expression of XBP1 and GRP78 is important for the survival of bone marrow cells in CCl4-treated cirrhotic liver2008
- Author(s)
  Marumoto Y, Terai S, Urata Y, Matsumoto T, Mizunaga Y, Yamamoto N, Jin H, Fujisawa K, Murata T, Shinoda K, Nishina H, Sakaida I
- Journal Title
  
  Biochem Biophys Res Commun 367(3)
  
  Pages: 546-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790486
[Journal Article] Continuous high expression of XBP1 and GRP78 is important for the survival of bone marrow cells in CCl4-treated cirrhotic liver.2008
- Author(s)
  Marumoto Y, Terai S, Urata Y, Matsumoto T, Mizunaga Y, Yamamoto N, Jin H, Fujisawa K, Murata T, Shinoda K, Nishina H, Sakaida I.
- Journal Title
  
  Biochem Biophys Res Commun. 14;367(3)
  
  Pages: 546-552
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790668
[Journal Article] Differentiation and enrichment of hepatocyte-like cells from human embryonic stem cells in vitro and in vivo2007
- Author(s)
  Duan Y, Catana A, Meng Y, Yamamoto N, He S,Gupta S, Gambhir SS, Zern MA
- Journal Title
  
  Stem cells 25(12)
  
  Pages: 3058-68
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790486
[Journal Article] Differentiation and enrichment of hepatocyte-like cells from human embryonic stem cells in vitro and in vivo.2007
- Author(s)
  Duan Y, Catana A, Meng Y, Yamamoto N, He S, Gupta S, Gambhir SS, Zern MA
- Journal Title
  
  Stem cells 25(12)
  
  Pages: 3058-68
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390199
[Journal Article] Telmisartan prevents hepatic fibrosis and enzyme-altered lesions in liver cirrhosis rat induced by a choline-deficient L-amino acid-defined diet.2007
- Author(s)
  Jin H, Yamamoto N, Uchida K, Terai S, Sakaida I
- Journal Title
  
  Biochem Biophys Res Commun 364(4)
  
  Pages: 801-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390199
[Patent] ソラフェニブの副作用低減剤2012
- Inventor(s)
  山本　直樹　　　山崎　隆弘　　　坂井田　功
- Industrial Property Rights Holder
  山口大学
- Industrial Property Rights Type
  特許
- Filing Date
  2012-11-05
- Data Source
  KAKENHI-PROJECT-24590978
[Patent] ソラフェニブの副作用低減剤2012
- Inventor(s)
  山本　直樹　山崎　隆弘　坂井田　功
- Industrial Property Rights Holder
  山口大学
- Industrial Property Rights Type
  特許
- Filing Date
  2012-11-05
- Data Source
  KAKENHI-PROJECT-23590978
[Patent] 分岐鎖アミノ酸（BCAA）による分子標的薬ソラフェニブの副作用軽減効果2011
- Inventor(s)
  山本　直樹
- Industrial Property Rights Holder
  山口大学
- Filing Date
  2011
- Data Source
  KAKENHI-PROJECT-23590978
[Patent] 分岐鎖アミノ酸(BCAA)による分子標的薬ソラフェニブの副作用軽減効果2011
- Inventor(s)
  山本直樹, 坂井田功
- Industrial Property Rights Holder
  山口大学
- Industrial Property Rights Type
  特許
- Filing Date
  2011-12-02
- Overseas
- Data Source
  KAKENHI-PROJECT-23590978
[Patent] ナトリウム利尿ペプチドを有効性成分とする肝硬変、前癌病変の抑制剤2008
- Inventor(s)
  山本直樹, 寺井崇二, 坂井田功
- Industrial Property Rights Holder
  山口大学
- Industrial Property Number
  2007-114293
- Acquisition Date
  2008-04-24
- Data Source
  KAKENHI-PROJECT-19390199
[Patent] ナトリウム利尿ペプチドを有効性成分とする肝硬変、前癌病変の抑制剤2007
- Inventor(s)
  山本直樹、寺井崇二、坂井田功
- Industrial Property Rights Holder
  山口大学
- Industrial Property Number
  2007-114293
- Filing Date
  2007-04-24
- Data Source
  KAKENHI-PROJECT-19390199
[Patent] ナトリウム利尿ペプチドを有効性成分とする肝硬変、前癌病変の抑制剤2007
- Inventor(s)
  山本直樹,寺井崇二,坂井田功
- Industrial Property Rights Holder
  山口大学
- Industrial Property Number
  2007-114293
- Acquisition Date
  2007-04-24
- Data Source
  KAKENHI-PROJECT-19790486
[Patent] ナトリウム利尿ペプチドを有効性成分とする肝硬変、前癌病変の抑制剤2007
- Inventor(s)
  山本直樹, 寺井崇二, 坂井田功
- Industrial Property Rights Holder
  山口大学
- Industrial Property Number
  2007-114293
- Acquisition Date
  2007-04-24
- Data Source
  KAKENHI-PROJECT-19790486
[Presentation] 培養自己骨髄間葉系幹細胞投与療法に対するexosomeを用いた補助療法の開発2022
- Author(s)
  原和冴, 松本俊彦, 藤澤浩一, 山本直樹, 高見太郎
- Organizer
  第21回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-20H03663
[Presentation] 医師主導治験「自己完結型肝硬変再生療法」の開発とNASH肝硬変への有効性評価2022
- Author(s)
  高見太郎, 松本俊彦, 大田久美江, 児玉雅季, 藤村瑠意, 小島奈緒美, 山本直樹, 坂井田功
- Organizer
  第21回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-20H03663
[Presentation] 医師主導治験「自己完結型肝硬変再生療法」の開発とNASH肝硬変への有効性評価2022
- Author(s)
  高見太郎, 松本俊彦, 大田久美江, 児玉雅季, 藤村瑠意, 小島奈緒美, 山本直樹, 坂井田功
- Organizer
  第21回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-18K08005
[Presentation] 肝線維化研究Revisited-肝臓学のBiologyからTranslationalへ肝星細胞とマクロファージの細胞間相互作用におけるmiR-142-3pの役割2022
- Author(s)
  松本俊彦, 山本直樹, 高見太郎
- Organizer
  第58回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-22K08057
[Presentation] 鉄キレート剤（DFO）投与により変化した代謝をターゲットとした併用療法の検討2022
- Author(s)
  藤澤浩一、松本俊彦、山本直樹、高見太郎
- Organizer
  第58回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-20K08358
[Presentation] 培養自己骨髄間葉系幹細胞投与療法に対するexosomeを用いた補助療法の開発2022
- Author(s)
  原和冴, 松本俊彦, 山本直樹, 高見太郎
- Organizer
  第29回肝細胞研究会
- Data Source
  KAKENHI-PROJECT-20K08386
[Presentation] 培養自己骨髄間葉系幹細胞投与療法に対するexosomeを用いた補助療法の開発2022
- Author(s)
  原和冴, 松本俊彦, 藤澤浩一, 山本直樹, 高見太郎
- Organizer
  第21回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-22K08057
[Presentation] 培養自己骨髄間葉系幹細胞投与療法に対するexosomeを用いた補助療法の開発2022
- Author(s)
  原和冴, 松本俊彦, 藤澤浩一, 山本直樹, 高見太郎
- Organizer
  第21回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-18K08005
[Presentation] 肝線維化研究Revisited-肝臓学のBiologyからTranslationalへ肝星細胞とマクロファージの細胞間相互作用におけるmiR-142-3pの役割2022
- Author(s)
  松本俊彦, 山本直樹, 高見太郎
- Organizer
  第58回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-20H03663
[Presentation] 医師主導治験「自己完結型肝硬変再生療法」の開発とNASH肝硬変への有効性評価2022
- Author(s)
  高見太郎、松本俊彦、大田久美江、児玉雅季、藤村瑠意、小島奈緒美、山本直樹、坂井田　功
- Organizer
  第21回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-20K08358
[Presentation] 培養自己骨髄間葉系幹細胞投与療法に対するexosomeを用いた補助療法の開発2022
- Author(s)
  原和冴, 松本俊彦, 藤澤浩一, 山本直樹, 高見太郎
- Organizer
  第21回再生医療学会総会
- Data Source
  KAKENHI-PROJECT-20K08386
[Presentation] 肝線維化研究Revisited-肝臓学のBiologyからTranslationalへ肝星細胞とマクロファージの細胞間相互作用におけるmiR-142-3pの役割2022
- Author(s)
  松本俊彦, 山本直樹, 高見太郎
- Organizer
  第58回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-18K08005
[Presentation] 鉄キレート剤（DFO）投与により変化した代謝をターゲットとした併用療法の検討2022
- Author(s)
  藤澤浩一, 松本俊彦, 山本直樹, 高見太郎
- Organizer
  第58回日本肝臓総会
- Data Source
  KAKENHI-PROJECT-20K08289
[Presentation] 医師主導治験「自己完結型肝硬変再生療法」の開発とNASH肝硬変への有効性評価2022
- Author(s)
  高見太郎, 松本俊彦, 大田久美江, 児玉雅季, 藤村瑠意, 小島奈緒美, 山本直樹, 坂井田功
- Organizer
  第21回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-22K08057
[Presentation] 鉄キレート剤(DFO)投与により起こる代謝変化を標的にした抗癌剤併用療法の検討2021
- Author(s)
  藤澤浩一, 松本俊彦, 山本直樹, 高見太郎
- Organizer
  第28回肝細胞研究会総会
- Data Source
  KAKENHI-PROJECT-20H03663
[Presentation] 培養自己骨髄間葉系幹細胞投与療法に対するmicroRNAを用いた補助療法の開発2021
- Author(s)
  原和冴, 松本俊彦, 藤澤浩一, 山本直樹, 高見太郎
- Organizer
  第35回肝類洞壁細胞研究会
- Data Source
  KAKENHI-PROJECT-18K08005
[Presentation] 鉄キレート剤（DFO）投与により起こる代謝変化を標的にした抗癌剤併用療法の検討2021
- Author(s)
  藤澤浩一, 松本俊彦, 山本直樹, 高見太郎
- Organizer
  第28回肝細胞研究会
- Data Source
  KAKENHI-PROJECT-20K08289
[Presentation] A novel anticancer therapy with deferoxamine and drugs targeting iron-chelation-modulated metabolism2021
- Author(s)
  Koichi Fujisawa, Toshihiko Matsumoto, Naoki Yamamoto, Takahiro Yamasaki, Taro, Takami
- Organizer
  The Asian Pacific Association for the Study of the Liver (APASL) OSAKA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08289
[Presentation] 培養自己骨髄間葉系幹細胞投与療法に対するmicroRNAを用いた補助療法の開発2021
- Author(s)
  原和冴、松本俊彦、藤澤浩一、山本直樹、高見太郎
- Organizer
  第35回肝類洞壁細胞研究会
- Data Source
  KAKENHI-PROJECT-20K08386
[Presentation] Infused bone marrow derived cells have important capacities that repair of fibrosis and phagocytosis of damaged cells2021
- Author(s)
  Naoki Yamamoto, Taro Takami, Koichi Fuzisawa, Toshihiko Matsumoto, Kenji Tani, Isao Sakaida
- Organizer
  The 19th Annual Meeting of the International Society for Stem Cell Research (ISSCR)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08005
[Presentation] 骨髄由来間葉系幹細胞におけるストレス応答機構の解明2020
- Author(s)
  笹井奈々実, 藤澤浩一, 高見太郎, 松本俊彦, 山本直樹, 西川潤, 坂井田功
- Organizer
  第19回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-20H03663
[Presentation] 健常異種動物の骨髄上清による培養骨髄間葉系幹細胞の高品質化2020
- Author(s)
  高見太郎, 宮地隆史, 藤澤浩一, 松本俊彦, 山本直樹,坂井田功
- Organizer
  第27回肝細胞研究会総会
- Data Source
  KAKENHI-PROJECT-20H03663
[Presentation] Infused bone marrow derived cells have important capacities that repair of fibrosis and phagocytosis of damaged cells2020
- Author(s)
  Naoki Yamamoto, Taro Takami, Koichi Fuzisawa,Toshihiko Matsumoto, Kenji Tani, Yasuho Taura, Isao Sakaida
- Organizer
  The 18th Annual Meeting of the International Society for Stem Cell Research (ISSCR)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08005
[Presentation] Hsa-miR-5682は肝星細胞における細胞外マトリックス蛋白および分子シャペロンの発現を網羅的に抑制する2020
- Author(s)
  松本俊彦, 藤澤浩一, 高見太郎, 山本直樹, 末広寛, 山崎隆弘, 坂井田功
- Organizer
  第106回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-20H03663
[Presentation] オートファジーに関わる NUPR1に着目した骨髄由来間葉系幹細胞のストレス耐性機構の評価2020
- Author(s)
  笹井奈々実、藤澤浩一、松本俊彦、高見太郎、山本直樹、西川潤、坂井田功
- Organizer
  第27回肝細胞研究会
- Data Source
  KAKENHI-PROJECT-20K08289
[Presentation] 骨髄由来間葉系幹細胞におけるストレス応答機構の解明2020
- Author(s)
  笹井奈々実、藤澤浩一、高見太郎、松本俊彦、山本直樹、西川潤、坂井田功
- Organizer
  第19回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-18K08005
[Presentation] Hsa-miR-5682は肝星細胞における細胞外マトリックス蛋白および分子シャペロンの発現を網羅的に抑制する2020
- Author(s)
  松本俊彦、藤澤浩一、高見太郎、山本直樹、坂井田功
- Organizer
  第106回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-18K08005
[Presentation] 改良コリン欠乏食マウス脂肪肝炎モデルにおける培養骨髄間葉系幹細胞投与の有効性評価と投与経路の検討2020
- Author(s)
  佐々木嶺、高見太郎、藤澤浩一、松本俊彦、山本直樹、坂井田功
- Organizer
  第56回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-18K08005
[Presentation] 骨髄由来間葉系幹細胞におけるストレス応答機構の解明2020
- Author(s)
  笹井奈々実、藤澤浩一、松本俊彦、高見太郎、山本直樹、西川潤、坂井田功
- Organizer
  第19回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-20K08289
[Presentation] 骨髄間葉系幹細胞を用いた肝臓再生療法に対する microRNAを用いた補助療法の開発2019
- Author(s)
  松本　俊彦、藤澤　浩一、高見　太郎、山本　直樹、末広　寛、山﨑　隆弘、坂井田　功
- Organizer
  第51回日本臨床形態分子学会
- Data Source
  KAKENHI-PROJECT-17H04162
[Presentation] Infused bone marrow derived cells have important capacities that repair of fibrosis and phagocytosis of damaged cells2019
- Author(s)
  Naoki Yamamoto, Taro Takami, Koichi Fuzisawa,Toshihiko Matsumoto, Kenji Tani, Yasuho Taura, Isao Sakaida
- Organizer
  The 17th Annual Meeting of the International Society for Stem Cell Research　(ISSCR)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08005
[Presentation] 改良コリン欠乏食マウス脂肪肝炎モデルにおける培養骨髄間葉系幹細胞投与の有効性評価と投与経路の検討2019
- Author(s)
  佐々木嶺、高見太郎、藤澤浩一、松本俊彦、山本直樹、坂井田功
- Organizer
  第43回日本肝臓学会西部会
- Data Source
  KAKENHI-PROJECT-18K08005
[Presentation] 核酸医薬品の開発を目指した肝星細胞におけるmiR142-3pの機能解析2019
- Author(s)
  松本俊彦、原和冴、藤澤浩一、高見太郎、山本直樹、山﨑隆弘、坂井田功
- Organizer
  第105回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-18K08005
[Presentation] microRNAの特性利用による抗線維化核酸医薬品の開発に向けた基礎検討2019
- Author(s)
  松本　俊彦、藤澤　浩一、高見　太郎、山本　直樹、山崎　隆弘、坂井田　功
- Organizer
  第55回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-17H04162
[Presentation] 改良コリン欠乏食マウス脂肪肝炎モデルにおける培養骨髄間葉系幹細胞投与の有効性評価と投与経路の検討2019
- Author(s)
  佐々木嶺、高見太郎、藤澤浩一、松本俊彦、山本直樹、坂井田功
- Organizer
  第55回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-18K08005
[Presentation] イヌ肝線維化評価モデルによる「肝硬変症に対する培養自己骨髄間葉系幹細胞肝動脈投与療法」の非臨床POC2018
- Author(s)
  西村達朗, 高見太郎, 佐々木嶺, 松田崇史, 藤澤浩一, 松本俊彦, 山本直樹, 坂井田功,
- Organizer
  第18回日本再生医療学会総会　神戸国際会議場
- Data Source
  KAKENHI-PROJECT-18K08005
[Presentation] 高脂肪食投与によるメダカ脂肪肝の代謝変化とTransparent(透明)メダカを用いたUltrasoundによる非侵襲的脂肪肝評価2018
- Author(s)
  藤澤浩一, 高見太郎, 福井悠美, 松本俊彦, 山本直樹,坂井田功
- Organizer
  第54回日本肝臓学会総会　大阪国際会議場
- Data Source
  KAKENHI-PROJECT-18K08005
[Presentation] 非代償性肝硬変症に対する培養自己骨髄間葉系幹細胞を末梢静脈投与する低侵襲再生療法の臨床実施2018
- Author(s)
  高見太郎, 松本俊彦, 久永拓郎, 宮地隆史, 佐々木嶺, 西村達朗, 仁志麻衣子, 松浦桂司, 松田崇史, 岩本拓也, 藤澤浩一, 丸本芳雄, 石川剛, 山本直樹, 坂井田功,
- Organizer
  第18回日本再生医療学会総会　神戸国際会議場
- Data Source
  KAKENHI-PROJECT-18K08005
[Presentation] 骨髄間葉系幹細胞によるmicroRNAを介した肝線維化改善機序の検討2018
- Author(s)
  仁志麻衣子, 松本俊彦, 藤澤浩一, 高見太郎, 山本直樹, 坂井田功
- Organizer
  第18回日本再生医療学会総会　神戸国際会議場
- Data Source
  KAKENHI-PROJECT-18K08005
[Presentation] Infused bone marrow derived cells have two capacities that repair of fibrosis and phagocytosis of damaged cells2018
- Author(s)
  Naoki Yamamoto,Taro Takami, Shuji Terai, Koichi Uchida, Koichi Fujisawa, Toshihiko Matsumoto, Kenji Tani, Hiroshi Nishina,Isao Sakaida.
- Organizer
  The 15th Annual Meeting of the International Society for Stem Cell Research(ISSCR) Melbourne
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08005
[Presentation] Nonclinical proof-of-concept for "hepatic artery infusion of cultured autologous bone marrow mesenchymal stem cells" in a canine liver fibrosis model2018
- Author(s)
  Tatsuro Nishimura, Taro Takami, Ryo Sasaki, Yuki Aibe, Takashi Matsuda, Toshihiko, Matsumoto, Koichi Fujisawa, Naoki Yamamoto, Isao Sakaida
- Organizer
  The Liver Meeting 2018, AASLD San Francisco USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08005
[Presentation] miR142‐3pによる肝線維化抑制効果の検討2018
- Author(s)
  松本俊彦, 仁志麻衣子, 藤澤浩一, 高見太郎, 山本直樹, 山崎隆弘, 坂井田功
- Organizer
  第54回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-16H05287
[Presentation] 骨髄間葉系幹細胞によるmicroRNAを介した肝線維化改善機序の検討2018
- Author(s)
  仁志麻衣子, 松本俊彦, 藤澤浩一, 高見太郎, 山本直樹, 坂井田功
- Organizer
  第54回日本肝臓学会総会　大阪国際会議場
- Data Source
  KAKENHI-PROJECT-18K08005
[Presentation] Direct infusion of cultured autologous bone marrow-derived mesenchymal stem cells offers higher therapeutic efficacy than conventional peripheral infusion in liver fibrosis animal models2018
- Author(s)
  Takami T, Sasaki R, Nishimura T, Matsuda T, Fujisawa K, Matsumoto T, Yamamoto N, Sakaida I.
- Organizer
  6th Annual Midwest Conference on Cell Therapy and Regenerative Medicine
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09428
[Presentation] Direct infusion of cultured autologous bone marrow-derived mesenchymal stem cells offers higher therapeutic efficacy than conventional peripheral infusion in liver fibrosis animal models2018
- Author(s)
  Takami T, Sasaki R, Nishimura T, Matsuda T, Fujisawa K, Matsumoto T, Yamamoto N, Sakaida I.
- Organizer
  6th Annual Midwest Conference on Cell Therapy and Regenerative Medicine
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04162
[Presentation] NAFLDに対するCa代謝調節による新規治療方法の確立のための基礎的検討2018
- Author(s)
  山本直樹, 高見太郎, 松本俊彦, 藤澤浩一, 宮地隆史, 佐々木領, 西村達郎, 松浦桂司, 仁志麻衣子,坂井田功,
- Organizer
  第54回日本肝臓学会総会　大阪国際会議場
- Data Source
  KAKENHI-PROJECT-18K08005
[Presentation] miR142‐3pによる肝線維化抑制効果の検討2018
- Author(s)
  松本俊彦, 仁志麻衣子, 藤澤浩一, 高見太郎, 山本直樹, 山崎隆弘, 坂井田功
- Organizer
  第54回日本肝臓学会総会　大阪国際会議場
- Data Source
  KAKENHI-PROJECT-18K08005
[Presentation] Arterial infusion of cultured autologous bone marrow mesenchymal stem cells has a stronger therapeutic effect on liver cirrhosis in our established canine model2018
- Author(s)
  Ryo Sasaki, Tatsuro Nishimura, Taro Takami, Yuki Aibe, Takashi Matsuda, Toshihiko, Matsumoto, Koichi Fujisawa, Naoki Yamamoto, Isao Sakaida
- Organizer
  The Liver Meeting 2018, AASLD San Francisco USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08005
[Presentation] 自己骨髄間葉系幹細胞を用いた肝臓再生療法の臨床実施と創薬への展開2018
- Author(s)
  松本俊彦, 高見太郎, 宮地隆史, 佐々木嶺, 西村達朗, 藤澤浩一, 岩本拓也, 石川剛, 山本直樹, 坂井田功
- Organizer
  第25回肝細胞研究会　東京大学
- Data Source
  KAKENHI-PROJECT-18K08005
[Presentation] イヌ線維化評価モデルによる培養自己骨髄間葉系幹細胞肝動脈投与の非臨床Proof of Conceptの取得2017
- Author(s)
  西村達朗、高見太郎、佐々木嶺、相部祐希、松田崇史、山本直樹、坂井田功
- Organizer
  第53回日本肝臓学会総会　広島
- Data Source
  KAKENHI-PROJECT-15K09005
[Presentation] 肝硬変症に対する自己骨髄細胞を用いた再生療法の開発と機序の解明2017
- Author(s)
  高見　太郎、松本　俊彦、仁志　麻衣子、西村達朗、佐々木嶺、相部祐希、松田崇史、藤澤　浩一、山本直樹、坂井田功
- Organizer
  第24回肝細胞研究会
- Data Source
  KAKENHI-PROJECT-17K09428
[Presentation] 骨髄間葉系幹細胞によるマクロファージMMP発現の制御2017
- Author(s)
  仁志麻衣子、松本俊彦、藤澤浩一、高見太郎、山本直樹、坂井田功
- Organizer
  第53回日本肝臓学会総会　広島
- Data Source
  KAKENHI-PROJECT-15K09005
[Presentation] 肝硬変症に対する自己骨髄細胞を用いた再生療法2017
- Author(s)
  高見　太郎松本　俊彦　藤澤　浩一　山本　直樹　坂井田　功
- Organizer
  第16回日本再生医療学会総会
- Place of Presentation
  仙台国際センター(宮城県・仙台市)
- Year and Date
  2017-03-07
- Data Source
  KAKENHI-PROJECT-15K09005
[Presentation] Infused bone marrow derived cells have two capacities that repair of fibrosis and phagocytosis of damaged cells2017
- Author(s)
  Naoki Yamamoto,Taro Takami, Shuji Terai, Koichi Uchida, Koichi Fujisawa, Toshihiko Matsumoto, Hiroshi Nishina,Isao Sakaida.
- Organizer
  The 14th Annual Meeting of the International Society for Stem Cell Research(ISSCR) Boston
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09005
[Presentation] マクロファージRho family GTPaseを標的とした肝線維溶解療法に向けた基盤研究2017
- Author(s)
  松本俊彦、仁志麻衣子、藤澤浩一、高見太郎、山本直樹、坂井田功
- Organizer
  第53回日本肝臓学会総会広島
- Data Source
  KAKENHI-PROJECT-15K09005
[Presentation] Nonclinical proof-of-concept for "hepatic artery infusion of cultured autologous bone marrow mesenchymal stem cells" in a canine liver fibrosis model2017
- Author(s)
  Tatsuro Nishimura, Taro Takami, Ryo Sasaki, Yuki Aibe, Takashi Matsuda, Toshihiko, Matsumoto, Koichi Fujisawa, Naoki Yamamoto, Isao Sakaida
- Organizer
  The Liver Meeting 2017, AASLD Washington DC
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09005
[Presentation] BCAA製剤によるSorafenibの治療効果増強と副作用軽減作用の解析2017
- Author(s)
  山本直樹、高見太郎、藤澤浩一、松本　俊彦、内田耕一、坂井田功
- Organizer
  第53回日本肝臓学会総会　広島
- Data Source
  KAKENHI-PROJECT-15K09005
[Presentation] 次世代型経口鉄キレート剤デフェラシロクスとゲムシタビンを併用した新規膵癌治療の基礎的研究2017
- Author(s)
  篠田祟平、戒能聖治、天野彰吾、安田真弓、仙譽学、松本俊彦、藤澤浩一、高見太郎、山本直樹、山﨑隆弘、坂井田功
- Organizer
  第103回　日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-16H05287
[Presentation] Hepatic arterial infusion of cultured autologous bone marrow mesenchymal stem cells has a stronger therapeutic effect on liver cirrhosis in our established canine model2016
- Author(s)
  Takami T, Aibe Y, Nishimura T, Matsuda T, Matsumoto T, Fujisawa K, Yamamoto N, Tani K, Taura Y, Sakaida I.
- Organizer
  ISSCR2016
- Place of Presentation
  San Francisco, USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461009
[Presentation] 肝臓再生療法における骨髄由来肝臓修復細胞の特徴2016
- Author(s)
  山本　直樹
- Organizer
  第15回日本再生医療学会総会
- Place of Presentation
  大阪国際会議場（大阪府・大阪市）
- Year and Date
  2016-03-17
- Data Source
  KAKENHI-PROJECT-15K09005
[Presentation] Arterial infusion of cultured autologous bone marrow mesenchymal stem cells has a stronger therapeutic effect on liver cirrhosis in our established canine model2016
- Author(s)
  Taro Takami, Yuki Aibe, Tatsuro Nishimura, Takashi Matsuda, Toshihiko Matsumoto, Koichi Fujisawa, Naoki Yamamoto, Kenji Tani, Yasuho Taura, Isao Sakaida
- Organizer
  International Society for Stem Cell Research 2016 (ISSCR2016)
- Place of Presentation
  San Francisco USA
- Year and Date
  2016-06-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09005
[Presentation] 肝硬変症に対する自己骨髄細胞を用いた肝臓再生療法2016
- Author(s)
  高見　太郎松本　俊彦　山本　直樹　藤澤　浩一　坂井田　功
- Organizer
  JDDW 2016
- Place of Presentation
  神戸国際会議場（兵庫県・神戸市）
- Year and Date
  2016-11-03
- Data Source
  KAKENHI-PROJECT-15K09005
[Presentation] Cultured bone marrow-derived mesenchymal stem cells contributed to improving liver cirrhosis through both the direct stabilization of redox homeostasis and cell-cell interaction with macrophages2016
- Author(s)
  Taro Takami, Toshihiko Matsumoto, Maiko Nishi, Koichi Fujisawa, Naoki Yamamoto, Isao Sakaida
- Organizer
  The Liver Meeting 2016, AASLD
- Place of Presentation
  Boston USA
- Year and Date
  2016-11-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09005
[Presentation] Effects of iron chelator, deferasirox, on hepatocellular carcinoma in basic and clinical studies.2016
- Author(s)
  Issei Saeki, Takahiro Yamasaki, Naoki Yamamoto, Koichi Fujisawa, Toshihiko Matsumoto, Taro Takami, Isao Sakaida.
- Organizer
  10th ILCA Annual Conference
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2016-09-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05287
[Presentation] 肝硬変症に対する新規SGLT2(Sodium-Glucose Co-Transporter2)阻害剤の治療効果の基礎的検証と機序解明2016
- Author(s)
  山本　直樹、高見太郎、藤澤浩一、松本俊彦、坂井田功
- Organizer
  第52回日本肝臓学会総会
- Place of Presentation
  ホテルニューオータニ幕張(千葉県・千葉市)
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-15K09005
[Presentation] 進行肝細胞癌に対する経口鉄キレート剤の治療戦略2016
- Author(s)
  佐伯一成、山本　直樹、高見太郎、山﨑隆弘、坂井田功
- Organizer
  第52回日本肝臓学会総会
- Place of Presentation
  ホテルニューオータニ幕張(千葉県・千葉市)
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-15K09005
[Presentation] The efficacy and safety of liver regeneration therapy by hepatic arterial infusion of cultured autologous bone marrow mesenchymal stem cells in our established canine cirrhotic model2016
- Author(s)
  Yuki Aibe, Taro Takami, Ryo Sasaki, Tatsuro Nishimura, Takashi Matsuda, Toshihiko Matsumoto, Koichi Fujisawa, Tsuyoshi Ishikawa, Naoki Yamamoto, Kenji Tani, Yasuho Taura, Isao Sakaida
- Organizer
  The Liver Meeting 2016, AASLD
- Place of Presentation
  Boston USA
- Year and Date
  2016-11-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09005
[Presentation] イヌ肝線維化モデル系における培養自己骨髄間葉系幹細胞投与の有効性評価2016
- Author(s)
  相部祐希、高見太郎、西村達朗、佐々木嶺、松田崇史、藤澤浩一、松本俊彦、石川剛、山本直樹、坂井田功
- Organizer
  第52回日本肝臓学会総会
- Place of Presentation
  ホテルニューオータニ幕張
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-15K09005
[Presentation] 進行肝細胞癌に対する経口鉄キレート剤の治療戦略2016
- Author(s)
  佐伯一成、山本直樹、坂井田　功.
- Organizer
  第52回日本肝臓学会総会
- Place of Presentation
  千葉県千葉市（ホテルニューオータニ幕張）
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-16H05287
[Presentation] Rho family GTPases regulate MMPs expression and pro-inflammatory phenotype of macrophages in fibrotic liver.2016
- Author(s)
  Toshihiko Matsumoto, Maiko Nishi, Koichi Fujisawa, Taro Takami, Naoki Yamamoto, Isao Sakaida
- Organizer
  The Liver Meeting 2016, AASLD
- Place of Presentation
  Boston USA
- Year and Date
  2016-11-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09005
[Presentation] Cultured bone marrow-derived mesenchymal stem cells contributed to improving liver cirrhosis through both the direct stabilization of redox homeostasis and cell-cell interaction with macrophages2016
- Author(s)
  Takami T, Matsumoto T, Nishi M, Fujisawa K, Yamamoto N, Sakaida I.
- Organizer
  The Liver meeting 2016, AASLD
- Place of Presentation
  Boston, USA
- Year and Date
  2016-11-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461009
[Presentation] Infused bone marrow derived cells have two capacities that repair of fibrosis and phagocytosis of damaged cells2016
- Author(s)
  Naoki Yamamoto,Taro Takami, Toshihiko Matsumoto, Koichi Uchida, Koichi Fujisawa, Isao Sakaida
- Organizer
  International Society for Stem Cell Research 2016 (ISSCR2016)
- Place of Presentation
  San Francisco USA
- Year and Date
  2016-06-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09005
[Presentation] レボカルニチンによるSASP現象抑制効果によるNAFLD治療の可能性2016
- Author(s)
  山本　直樹、高見太郎、藤澤浩一、松本俊彦、坂井田功
- Organizer
  第52回日本肝臓学会総会
- Place of Presentation
  ホテルニューオータニ幕張(千葉県・千葉市)
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-15K09005
[Presentation] レボカルニチンによるNAFLD治療効果の基礎的検討2015
- Author(s)
  山本　直樹
- Organizer
  第51回日本肝臓学会総会
- Place of Presentation
  熊本ホテル日航（熊本県・熊本市）
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-15K09005
[Presentation] L-carnitine prevents liver fibrosis and preneoplastic lesions in rat liver cirrhosis model induced by a choline-deficient L-amino acid-defined diet(CDAA) and Diethylnitrosamine (DEN)2015
- Author(s)
  Naoki Yamamoto
- Organizer
  The 23th United European Gastroenterology Week (UEGW 2015)
- Place of Presentation
  Barcelona Convention Center (Spain)
- Year and Date
  2015-10-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09005
[Presentation] 新規SGLT2(Sodium-Glucose Co-Transporter2)阻害剤の肝線維化抑制効果の基礎的検討2015
- Author(s)
  山本　直樹
- Organizer
  第51回日本肝臓学会総会
- Place of Presentation
  熊本ホテル日航（熊本県・熊本市）
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-15K09005
[Presentation] 非代償性肝硬変に対する自己骨髄細胞を用いた肝再生療法2015
- Author(s)
  高見　太郎、相部　祐希、松田　崇史、久永　拓郎、岩本　拓也、藤澤　浩一、松本　俊彦、丸本　芳雄、石川　剛、山本　直樹、谷　健二、藤井　康彦、田浦　保穂、寺井　崇二、坂井田　功
- Organizer
  第22回肝細胞研究会
- Place of Presentation
  鳥取県米子市（Big Ship）
- Year and Date
  2015-06-04
- Data Source
  KAKENHI-PROJECT-26461009
[Presentation] Infused bone marrow derived cells have two capacities that phagocytosis of damaged cells and repair of fibrosis in mice2015
- Author(s)
  Naoki Yamamoto
- Organizer
  The 12th Annual Meeting of the International Society for Stem Cell Research　(ISSCR) 2015
- Place of Presentation
  Stockholm convention center (Sweden)
- Year and Date
  2015-06-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09005
[Presentation] Less invasive liver regeneration therapy for liver cirrhosis patients using cultured autologous bone marrow-derived mesenchymal stem cells2015
- Author(s)
  Takami T, Aibe Y, Matsuda T, Matsumoto T, Fujisawa K, Yamamoto N, Terai S, Sakaida I.
- Organizer
  ISSCR2015
- Place of Presentation
  Stockholm, Sweden
- Year and Date
  2015-06-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461009
[Presentation] 肝癌におけるアデニル酸キナーゼアイソザイムの低酸素耐性2014
- Author(s)
  藤澤浩一、野間隆文、高見太郎、山本直樹、寺井崇二、坂井田功
- Organizer
  薬剤耐性に関わるメカニズムの解明消化器とフリーラジカル研究会
- Place of Presentation
  京都都ホテル(京都)
- Year and Date
  2014-03-08
- Data Source
  KAKENHI-PROJECT-24659369
[Presentation] The new oral iron chelator, Deferasirox, is the new drug to prevent Liver Fibrosis and Hepatocarcinogenesis2013
- Author(s)
  Naoki Yamamoto, Takahiro Yamasaki, Koichi Uchida, Norikazu Tanabe, Taro Takami, Issei Saeki, Koichi Fujisawa, Masaki Maeda, Shuji Terai, Isao Sakaida
- Organizer
  64th Annual Liver Meeting in AASLD 2013
- Place of Presentation
  Washington Convention Center(Washington DC USA)
- Data Source
  KAKENHI-PROJECT-23590978
[Presentation] The new oral iron chelator prevents liver fibrosis and preneoplastic lesions in liver cancer and liver cirrhosis model2013
- Author(s)
  Naoki Yamamoto
- Organizer
  The 21st United European Gastroenterology Week (UEGW /Gastro 2013 )
- Place of Presentation
  ICC, Berlin (Germany)
- Data Source
  KAKENHI-PROJECT-24590978
[Presentation] Serum transferrin as a predictor of prognosis for hepatic arterial infusion chemotherapy in advanced hepatocellular carcinoma2013
- Author(s)
  Takahiro Yamasaki, Issei Saeki, Junichi Zaitsu, Yohei Harima, Takuya Iwamoto, Yumiko Harima, Toshihiko Matsumoto, Yohei Urata, Isao Hidaka, Yoshio Marumoto, Tsuyoshi Ishikawa, Taro Takami, Naoki Yamamoto, Seiji Kaino, Koichi Uchida, Shuji Terai, Isao Sakaida
- Organizer
  The 23rd Conference of the Asian Pacific Association for the Study of the Liver（APASL) 2013
- Place of Presentation
  Suntec Singapole(Singapole)
- Data Source
  KAKENHI-PROJECT-23590978
[Presentation] The new oral iron chelater prevent Liver fibrosis and preneoplastic lesion s in liver cancer and liver cirrhosis model2013
- Author(s)
  Yamamoto N, Yamasaki T, Terai S, Sakaida I, et al.
- Organizer
  23^<th> Conference of the Asian Pacific Association for the Study of the Liver (APASL) 2013
- Place of Presentation
  Suntec Singapole, Singapole
- Year and Date
  2013-06-08
- Data Source
  KAKENHI-PROJECT-23590978
[Presentation] Serum transferrin as a predictor of prognosis for hepatic arterial infusion chemotherapy in advanced hepatocellular carcinoma2013
- Author(s)
  Yamasaki T, Yamamoto N, Terai S, Sakaida I, et al.
- Organizer
  23^<th> Conference of the Asian Pacific Association for the Study of the Liver (APASL) 2013
- Place of Presentation
  Suntec Singapole, Singapole
- Year and Date
  2013-06-07
- Data Source
  KAKENHI-PROJECT-23590978
[Presentation] The new oral iron chelator Deferasirox prevents liver fibrosis and preneoplastic lesions in rat liver cirrhosis induced2013
- Author(s)
  Naoki Yamamoto, Takahiro Yamasaki, Teiichi Hirose, Taro Takami, Koichi Fujisawa, Masaki Maeda, Koichi Uchida, Issei Saeki, Shuji Terai, Isao Sakaida
- Organizer
  The 23rd Conference of the Asian Pacific Association for the Study of the Liver（APASL) 2013
- Place of Presentation
  Suntec Singapole(Singapole)
- Data Source
  KAKENHI-PROJECT-23590978
[Presentation] The new oral iron chelator, Deferasirox, is the new drug to prevent Liver Fibrosis and Hepatocarcinogenesis2013
- Author(s)
  Naoki Yamamoto
- Organizer
  AASLD's 64th Annual Liver Meeting 2013
- Place of Presentation
  Washington Convention Center(Washington USA)
- Data Source
  KAKENHI-PROJECT-24590978
[Presentation] The new oral iron chelator prevents liver fibrosis and preneoplastic lesions in liver cancer and liver cirrhosis model2013
- Author(s)
  Naoki Yamamoto, Takahiro Yamasaki, Koichi Uchida, Taro Takami, Koichi Fujisawa, Masaki Maeda, Issei Saeki, Shuji Terai, Isao Sakaida
- Organizer
  The 21st United European Gastroenterology Week (UEGW /Gastro 2013 )
- Place of Presentation
  ICC Berlin(Germany)
- Data Source
  KAKENHI-PROJECT-23590978
[Presentation] The new oral iron chelater prevent Liver fibrosis and preneoplastic lesion s in liver cancer and liver cirrhosis model2013
- Author(s)
  Yamamoto N, Yamasaki T, Terai S, Sakaida I, et al.
- Organizer
  21^<th> United European gastroenterology Week(UEGW) 2013
- Place of Presentation
  ICC Berlin Germany
- Year and Date
  2013-10-15
- Data Source
  KAKENHI-PROJECT-23590978
[Presentation] The new oral iron chelater,Defeeasirox,is the new drug to prevent Liver fibrosis and Hepatocarcinogenesis2013
- Author(s)
  Yamamoto N, Yamasaki T, Terai S, Sakaida I, et al.
- Organizer
  64^<th> Annual Liver Meeting in AASLD 2013
- Place of Presentation
  Washington Convention Center Washington DC USA
- Year and Date
  2013-11-05
- Data Source
  KAKENHI-PROJECT-23590978
[Presentation] 鉄キレート剤による肝線維化・肝発癌抑制効果の検討2012
- Author(s)
  山本　直樹
- Organizer
  第26回肝類洞壁細胞研究会学術集会
- Place of Presentation
  ANAクラウンプラザホテル宇部(山口）
- Data Source
  KAKENHI-PROJECT-24590978
[Presentation] 鉄キレート剤による肝線維化・肝発癌抑制効果の検討2012
- Author(s)
  山本　直樹
- Organizer
  第26回肝類洞壁細胞研究会学術集会
- Place of Presentation
  ANAクラウンプラザホテル宇部 (宇部)
- Data Source
  KAKENHI-PROJECT-23590978
[Presentation] 肝細胞癌治療に対する鉄キレート剤の新規治療薬としての可能性2012
- Author(s)
  山本直樹,寺井崇二,山﨑隆弘,坂井田功, 他
- Organizer
  第48回日本肝臓学会総会
- Place of Presentation
  ANAクラウンプラザホテル,金沢
- Year and Date
  2012-06-07
- Data Source
  KAKENHI-PROJECT-23590978
[Presentation] 肝細胞癌治療に対する鉄キレート剤の新規治療薬としての可能性2012
- Author(s)
  山本　直樹
- Organizer
  第48回日本肝臓学会総会
- Place of Presentation
  ANAクラウンプラザホテル金沢 (金沢)
- Data Source
  KAKENHI-PROJECT-23590978
[Presentation] Dipeptidyl peptidase-4(DPP IV) inhibitor prevents liver fibrosis and preneoplastic lesion in rat liver cirrhosis induced by a choline-deficient L-amino acid-defined diet2012
- Author(s)
  Yamamoto Naoki
- Organizer
  United European Gastroenterology Week (UEGW /Gastro 2012 )
- Place of Presentation
  Amsterdam, Netherlands
- Data Source
  KAKENHI-PROJECT-24590978
[Presentation] SMP30/Regucalcin is a useful marker for liver tumor2011
- Author(s)
  Koichi Fujisawa, Shuji Terai, Taro Takami, Naoki Yamamoto, Isao Sakaida
- Organizer
  ISHSR
- Place of Presentation
  フィレンツェィタリア
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-22659148
[Presentation] 肝線維化修復時における二種類の骨髄由来細胞の動態と特徴2011
- Author(s)
  山本直樹
- Organizer
  第47回日本肝臓学会総会
- Place of Presentation
  東京グランパシフィック LE DAIBA
- Year and Date
  2011-06-05
- Data Source
  KAKENHI-PROJECT-22390150
[Presentation] Two kind of bone marrow cells phagocyte damaged hepatocyte and repair fibrosis in cirrhosis mice2011
- Author(s)
  Yamamoto Naoki
- Organizer
  The 62th Annual Meeting of the American Association for the study of Liver Diseases (AASLD)
- Place of Presentation
  San Francisco USA
- Year and Date
  2011-11-06
- Data Source
  KAKENHI-PROJECT-22390150
[Presentation] 肝線維化修復時における二種類の骨髄由来細胞の動態と特徴2011
- Author(s)
  山本直樹
- Organizer
  第47回日本肝臓学会総会
- Place of Presentation
  グランパシフィックLE DAIBA,東京
- Year and Date
  2011-06-02
- Data Source
  KAKENHI-PROJECT-22390150
[Presentation] HHM(Maid) is a specific regulator to inhibit the generation of liver tumor and progression of liver fibrosis-From the studyof CCl4 induced Maid KO mice and DEN exposure HHM Tg medaka fish-2011
- Author(s)
  Shuji Terai, Naoki Yamamoto, Koichi Fujisawa, Tomoaki Murata, Isao Sakaida
- Organizer
  The Liver Meeting 2011
- Place of Presentation
  アメリカ　サンフランシスコ
- Data Source
  KAKENHI-PROJECT-23659398
[Presentation] 肝線維化修復時における二種類の骨髄由来細胞の動態と特徴2011
- Author(s)
  山本直樹
- Organizer
  第25回肝類洞壁細胞研究会学術集会
- Place of Presentation
  東京ガーデンパレス東京
- Year and Date
  2011-11-18
- Data Source
  KAKENHI-PROJECT-22390150
[Presentation] SMP30/ Regucalcin is a useful marker for liver tumor ISHSR2011
- Author(s)
  Koichi Fujisawa, Shuji Terai, Taro Takami, Naoki Yamamoto, Isao Sakaida
- Place of Presentation
  フィレンツェイタリア
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-22659148
[Presentation] 免疫電顕を用いた骨髄由来肝幹細胞の肝硬変の修復時の各種細胞の動態2011
- Author(s)
  山本直樹
- Organizer
  第10回日本再生医療学会総会
- Place of Presentation
  東京京王ブラザホテル
- Year and Date
  2011-03-19
- Data Source
  KAKENHI-PROJECT-21790668
[Presentation] SMP30/Regucalcin is a useful marker for liver tumor2011
- Author(s)
  Koichi Fujisawa, Shuji Terai, Taro Takami, Naoki Yamamoto, Isao Sakaida
- Organizer
  ISHSR
- Place of Presentation
  イタリア　フィッレンッエ
- Data Source
  KAKENHI-PROJECT-23659398
[Presentation] Two kind of bone marrow cells phagocyte damaged hepatocyte and repair fibrosis in cirrhosis mice2011
- Author(s)
  Yamamoto Naoki
- Organizer
  The 62th AASLD meeting
- Place of Presentation
  San Francisco USA
- Year and Date
  2011-11-03
- Data Source
  KAKENHI-PROJECT-22390150
[Presentation] The Electron Microscopical Analysis for cell lineage of bone marrow cell differentiation in cirrhosis mice2010
- Author(s)
  Yamamoto Naoki
- Organizer
  The 15th ISHSR meeting
- Place of Presentation
  Pasadena USA
- Year and Date
  2010-08-25
- Data Source
  KAKENHI-PROJECT-22390150
[Presentation] 防風通聖散・大柴胡湯によるコリン欠乏食誘発ラット肝硬変モデルにおける肝線維化抑制及び前癌性病変発生抑制効果ついての検討2010
- Author(s)
  内田耕一、山本直樹、寺井崇二、桑代紳哉、大石俊之、山崎隆弘、坂井田功
- Organizer
  第46回日本肝臓学会総
- Place of Presentation
  ホテルメトロポリタン山形
- Year and Date
  2010-05-27
- Data Source
  KAKENHI-PROJECT-22590657
[Presentation] 免疫電顕を用いた骨髄由来肝幹細胞の肝硬変の修復時の各種細胞の動態2010
- Author(s)
  山本直樹
- Organizer
  第9回日本再生医療学会総会
- Place of Presentation
  広島
- Year and Date
  2010-03-18
- Data Source
  KAKENHI-PROJECT-19390199
[Presentation] 骨髄中の肝幹細胞の動態と微細構造解析-GFP/CCl4モデル-2010
- Author(s)
  山本直樹
- Organizer
  第9回日本再生医療学会総会
- Place of Presentation
  広島
- Year and Date
  2010-03-19
- Data Source
  KAKENHI-PROJECT-21790668
[Presentation] THE ELECTRON MICROSCOPICAL ANALYSIS FOR CELL LINEAGE OF BONE MARROW CELL DIFFERENTIATION IN CIRRHOSIS MICE2010
- Author(s)
  Naoki Yamamoto
- Organizer
  The 3th ISHSR meeting Pasaseda USA
- Place of Presentation
  Pasaseda,USA
- Year and Date
  2010-08-28
- Data Source
  KAKENHI-PROJECT-21790668
[Presentation] 骨髄細胞投与による肝修復機構におけるTNFαシグナルの関与についての検討2010
- Author(s)
  久永拓郎山本直樹寺井崇二坂井田功
- Organizer
  第9回日本再生医療学会総会
- Place of Presentation
  広島
- Year and Date
  2010-03-18
- Data Source
  KAKENHI-PROJECT-19390199
[Presentation] 骨髄中の肝幹細胞の動態と微細構造解析-GFP/CCl4モデル-2010
- Author(s)
  山本直樹
- Organizer
  第9回日本再生医療学会総会
- Place of Presentation
  広島・広島国際会議場
- Year and Date
  2010-03-15
- Data Source
  KAKENHI-PROJECT-21790668
[Presentation] GFP/CCl4モデルにおける微細構造解析からの骨髄中の肝幹細胞の動態解析2010
- Author(s)
  山本直樹寺井崇二坂井田功
- Organizer
  第9回日本再生医療学会総会
- Place of Presentation
  広島
- Year and Date
  2010-03-18
- Data Source
  KAKENHI-PROJECT-19390199
[Presentation] 漢方薬(防風通聖散・大柴胡湯)による肝脂肪化・肝線維化抑制効果について2010
- Author(s)
  内田耕一、山本直樹、桑代紳哉、大石俊之、寺井崇二、坂井田功
- Organizer
  第31回日本肥満学会
- Place of Presentation
  群馬前橋テルサ
- Year and Date
  2010-10-01
- Data Source
  KAKENHI-PROJECT-22590657
[Presentation] 脾臓摘出によるABMI療法の肝線維化、肝再生効果に対する臨床、基礎的検討2010
- Author(s)
  岩本拓也山本直樹寺井崇二坂井田功
- Organizer
  第9回日本再生医療学会総会
- Place of Presentation
  広島
- Year and Date
  2010-03-18
- Data Source
  KAKENHI-PROJECT-19390199
[Presentation] 骨髄由来肝幹細胞の肝硬変修復時における様々な動態と微細構造解析2010
- Author(s)
  山本直樹
- Organizer
  第46回日本肝臓学会総会
- Place of Presentation
  山形テルサ
- Year and Date
  2010-05-31
- Data Source
  KAKENHI-PROJECT-21790668
[Presentation] THE ELECTRON MICROSCOPICAL ANALYSIS FOR CELL LINEAGE OF BONE MARROW CELL DIFFERENTIATION IN CIRRHOSIS MICE2010
- Author(s)
  Naoki Yamamoto
- Organizer
  The 3th ISHSR meeting
- Place of Presentation
  Pasaseda USA
- Year and Date
  2010-08-28
- Data Source
  KAKENHI-PROJECT-21790668
[Presentation] THE ELECTRON MICROSCOPICAL ANALYSIS FOR CELL LINEAGE OF BONEMARROW CELL DIFFERENTIATION IN CIRRHOSIS MICE2009
- Author(s)
  Naoki Yamamoto
- Organizer
  第60回AASLD(The American Association for the Study of Liver Disease)
- Place of Presentation
  Boston USA
- Year and Date
  2009-11-03
- Data Source
  KAKENHI-PROJECT-21790668
[Presentation] THE ELECTRON MICROSCOPICAL ANALYSIS FOR CELL LINEAGE OF BONE MARROW CELL DIFFERENTIATION IN CIRRHOSIS MICE2009
- Author(s)
  山本直樹
- Organizer
  第60回AASLD(The American Association for the Study of Liver Disease)
- Place of Presentation
  Boston USA
- Year and Date
  2009-11-03
- Data Source
  KAKENHI-PROJECT-19390199
[Presentation] THE ELECTRON MICROSCOPICAL ANALYSIS FOR CELL LINEAGE OF BONE MARROW CELL DIFFERENTIATION IN CIRRHOSIS MICE2009
- Author(s)
  Naoki Yamamoto
- Organizer
  第17回UEGW/Gastro 2009(United European Gastroenterology Week)
- Place of Presentation
  London UK
- Year and Date
  2009-11-24
- Data Source
  KAKENHI-PROJECT-21790668
[Presentation] THE ELECTRON MICROSCOPICAL ANALYSIS FOR CELL LINEAGE OF BONE MARROW CELL DIFFERENTIATION IN CIRRHOSIS MICE.2009
- Author(s)
  Yamamoto N, Terai S, Sakaida I
- Organizer
  第60回AASLD(The American Association for the Study of Liver Disease)
- Place of Presentation
  Boston USA
- Year and Date
  2009-11-02
- Data Source
  KAKENHI-PROJECT-19390199
[Presentation] GFP/CC14モデルにおける微細構造解析からの骨髄中の肝幹細胞の動態解析2009
- Author(s)
  山本直樹
- Organizer
  第8回日本再生医療学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19390199
[Presentation] 肝硬変症に対するラエンネックの肝機能改善効果に対する検討2009
- Author(s)
  久永拓郎山本直樹寺井崇二坂井田功
- Organizer
  第8回日本再生医療学会総会
- Place of Presentation
  東京
- Year and Date
  2009-03-05
- Data Source
  KAKENHI-PROJECT-19390199
[Presentation] 免疫電顕を用いた骨髄由来肝幹細胞の肝硬変の修復時の各種細胞の動態2009
- Author(s)
  山本直樹
- Organizer
  第45回日本肝臓学会総会
- Place of Presentation
  神戸・神戸国際会議場
- Year and Date
  2009-06-05
- Data Source
  KAKENHI-PROJECT-21790668
[Presentation] GFP/CCl4モデルにおける微細構造解析からの骨髄中の肝幹細胞の動態解析2009
- Author(s)
  山本直樹寺井崇二坂井田功
- Organizer
  第8回日本再生医療学会総会
- Place of Presentation
  東京
- Year and Date
  2009-03-05
- Data Source
  KAKENHI-PROJECT-19390199
[Presentation] HE ELECTRON MICROSCOPICAL ANALYSIS FOR CELL LINEAGE OF BONE MARROW CELL DIFFERENTIATION IN CIRRHOSIS MICE2009
- Author(s)
  山本直樹
- Organizer
  第17回UEGW/G/Gastro 2009(United European Gastroenterology Week)
- Place of Presentation
  London UK
- Year and Date
  2009-11-26
- Data Source
  KAKENHI-PROJECT-19390199
[Presentation] TNF-alpha signal is important to repair cirrhotic liver by bone marrow cell infusion2009
- Author(s)
  Hisanaga T, Terai S, Iwamoto T, Takami T, Yamamoto N, Nishina H, Sakaida I
- Organizer
  第60回AASLD(The American Association for the Study of Liver Disease)
- Place of Presentation
  Boston USA
- Year and Date
  2009-11-01
- Data Source
  KAKENHI-PROJECT-19390199
[Presentation] GFP/CCl4モデルにおける微細構造解析からの骨髄中の肝幹細胞の動態解析2009
- Author(s)
  山本直樹
- Organizer
  第8回日本再生医療学会総会
- Place of Presentation
  東京
- Year and Date
  2009-03-05
- Data Source
  KAKENHI-PROJECT-19790486
[Presentation] 免疫電顕を用いた骨髄由来肝幹細胞の肝硬変の修復時の各種細胞の動態2009
- Author(s)
  山本直樹寺井崇二坂井田功
- Organizer
  第45回日本肝臓学会総会
- Place of Presentation
  神戸
- Year and Date
  2009-06-05
- Data Source
  KAKENHI-PROJECT-19390199
[Presentation] plenectomy enhances the effect of bone marrow cell infusion on the repair of the microenvironment in mice and patients with liver cirrhosis2009
- Author(s)
  Iwamoto T, Terai S, Yamamoto N, Sakaida I
- Organizer
  第60回AASLD(The American Association for the Study of Liver Disease)
- Place of Presentation
  Boston USA
- Year and Date
  2009-10-31
- Data Source
  KAKENHI-PROJECT-19390199
[Presentation] 免疫電顕を用いた骨髄由来肝幹細胞の肝硬変の修復時の各種細胞の動態2009
- Author(s)
  山本直樹
- Organizer
  第23回肝類洞壁細胞研究会
- Place of Presentation
  大阪・ホテル京阪ユニバーサルタワー
- Year and Date
  2009-12-16
- Data Source
  KAKENHI-PROJECT-21790668
[Presentation] 免疫電顕を用いた骨髄由来肝幹細胞の肝硬変の修復時の各種細胞の動態2009
- Author(s)
  山本直樹寺井崇二坂井田功
- Organizer
  第16回肝細胞研究会
- Place of Presentation
  山形
- Year and Date
  2009-06-26
- Data Source
  KAKENHI-PROJECT-19390199
[Presentation] 免疫電顕を用いた骨髄由来細胞の肝硬変修復時の動態と各種特徴2009
- Author(s)
  山本直樹
- Organizer
  第5回広島肝臓プロジェクト研究センターシンポジウム
- Place of Presentation
  広島・広島広仁会館
- Year and Date
  2009-09-15
- Data Source
  KAKENHI-PROJECT-21790668
[Presentation] 免疫電顕を用いた骨髄由来肝幹細胞の肝硬変の修復時の各種細胞の動態2009
- Author(s)
  山本直樹
- Organizer
  第16回肝細胞研究会
- Place of Presentation
  山形
- Year and Date
  2009-06-20
- Data Source
  KAKENHI-PROJECT-21790668
[Presentation] 免疫電顕を用いた骨髄由来肝幹細胞の肝硬変の修復時の各種細胞の動態2009
- Author(s)
  山本直樹
- Organizer
  第16回肝細胞研究会
- Place of Presentation
  山形・山形テルサ
- Year and Date
  2009-06-20
- Data Source
  KAKENHI-PROJECT-21790668
[Presentation] GFP/CCl4モデルにおける微細構造解析からの骨髄中の肝幹細胞の動態解析2009
- Author(s)
  山本直樹
- Organizer
  第41回日本臨床分子形態学会
- Place of Presentation
  神戸
- Year and Date
  2009-09-25
- Data Source
  KAKENHI-PROJECT-21790668
[Presentation] 免疫電顕を用いた骨髄由来肝幹細胞の肝硬変の修復時の各種細胞の動態2009
- Author(s)
  山本直樹
- Organizer
  第23回肝類洞壁細胞研究会
- Place of Presentation
  大阪
- Year and Date
  2009-12-23
- Data Source
  KAKENHI-PROJECT-21790668
[Presentation] THE ELECTRON MICROSCOPICAL ANALYSIS FOR CELL LINEAGE OF BONE MARROW CELL DIFFERENTIATION IN CIRRHOSIS MICE.2009
- Author(s)
  Yamamoto N, Terai S, Sakaida I
- Organizer
  第17回UEGW/Gastro 2009(United European Gastroenterology Week)
- Place of Presentation
  London UK
- Year and Date
  2009-11-25
- Data Source
  KAKENHI-PROJECT-19390199
[Presentation] 免疫電顕を用いた骨髄由来肝幹細胞の肝硬変の修復時の各種細胞の動態2009
- Author(s)
  山本直樹
- Organizer
  第23回肝類洞壁細胞研究会
- Place of Presentation
  大阪
- Year and Date
  2009-12-23
- Data Source
  KAKENHI-PROJECT-19390199
[Presentation] 免疫電顕を用いた骨髄由来細胞の肝硬変修復時の動熊と各種特徴2009
- Author(s)
  山本直樹
- Organizer
  第5回広島肝臓プロジェクト研究センターシンポジウム
- Place of Presentation
  広島
- Year and Date
  2009-09-15
- Data Source
  KAKENHI-PROJECT-19390199
[Presentation] 免疫電顕を用いた骨髄由来肝幹細胞の肝硬変の修復時の各種細胞の動熊2009
- Author(s)
  山本直樹
- Organizer
  第16回肝細胞研究会
- Place of Presentation
  山形
- Year and Date
  2009-06-19
- Data Source
  KAKENHI-PROJECT-19390199
[Presentation] 骨髄細胞投与による肝修復機構におけるTNFαシグナルの関与についての検討2009
- Author(s)
  久永拓郎山本直樹寺井崇二坂井田功
- Organizer
  第45回日本肝臓学会総会
- Place of Presentation
  神戸
- Year and Date
  2009-06-05
- Data Source
  KAKENHI-PROJECT-19390199
[Presentation] 脾臓摘出によるABMI療法の肝線維化、肝再生効果に対する臨床、基礎的検討2009
- Author(s)
  岩本拓也山本直樹寺井崇二坂井田功
- Organizer
  第8回日本再生医療学会総会
- Place of Presentation
  東京
- Year and Date
  2009-03-05
- Data Source
  KAKENHI-PROJECT-19390199
[Presentation] THE ELECTRON MICROSCOPICAL ANALYSIS FOR CELL LINEAGE OF BONEMARROW CELL DIFFERENTIATION IN CIRRHOSIS MICE2009
- Author(s)
  Naoki Yamamoto
- Organizer
  第17回LUEGW/Gastro 2009(United European Gastroenterology Week)
- Place of Presentation
  London UK
- Year and Date
  2009-11-24
- Data Source
  KAKENHI-PROJECT-21790668
[Presentation] 免疫電顕を用いた骨髄由来肝幹細胞の肝硬変の修復時の各種細胞の動態2009
- Author(s)
  山本直樹
- Organizer
  第45回日本肝臓学会総会
- Place of Presentation
  神戸
- Year and Date
  2009-06-05
- Data Source
  KAKENHI-PROJECT-21790668
[Presentation] 脾臓摘出術の自己骨髄細胞投与療法に対する臨床、基礎的検討2009
- Author(s)
  岩本拓也山本直樹寺井崇二坂井田功
- Organizer
  第45回日本肝臓学会総会
- Place of Presentation
  神戸
- Year and Date
  2009-06-05
- Data Source
  KAKENHI-PROJECT-19390199
[Presentation] 免疫電顕を用いた骨髄由来肝幹細胞の肝硬変の修復時の各種細胞の動熊2009
- Author(s)
  山本直樹
- Organizer
  第45回日本肝臓学会総会
- Place of Presentation
  神戸
- Year and Date
  2009-06-05
- Data Source
  KAKENHI-PROJECT-19390199
[Presentation] THE ELECTRON MICROSCOPICAL ANALYSIS FOR CELL LINEAGE OF BONE MARROW CELL DIFFERENTIATION IN CIRRHOSIS MICE2009
- Author(s)
  Naoki Yamamoto
- Organizer
  第60回AASLD(The American Association for the Study of Liver Disease)
- Place of Presentation
  Boston USA
- Year and Date
  2009-11-03
- Data Source
  KAKENHI-PROJECT-21790668
[Presentation] 免疫電顕を用いた骨髄由来細胞の肝硬変修復時の動態と各種特徴2009
- Author(s)
  山本直樹
- Organizer
  第5回広島肝臓プロジェクト研究センターシンポジウム
- Place of Presentation
  広島
- Year and Date
  2009-09-15
- Data Source
  KAKENHI-PROJECT-21790668
[Presentation] ナトリウム利尿ポリペプチド製剤による肝線維化抑制効果についての検討2008
- Author(s)
  山本直樹
- Organizer
  第94回日本消化器病学会総会
- Place of Presentation
  福岡
- Year and Date
  2008-05-15
- Data Source
  KAKENHI-PROJECT-19790486
[Presentation] 脾臓摘出術併用骨髄細胞投与による肝硬変の改善の検討2008
- Author(s)
  岩本拓也山本直樹寺井崇二坂井田功
- Organizer
  第44回日本肝臓学会総会
- Place of Presentation
  愛媛
- Year and Date
  2008-06-04
- Data Source
  KAKENHI-PROJECT-19390199
[Presentation] 防風通聖散のコリン欠乏性ラット肝硬変モデルに対する肝線維化・肝発癌抑制効果についての検討2008
- Author(s)
  内田耕一、山本直樹、寺井崇二、水永裕子、岩本拓也、桑代紳哉、坂井田功
- Organizer
  第59回アメリカ肝臓病学会(AASLD)
- Place of Presentation
  米国、サンフランシスコ
- Year and Date
  2008-11-03
- Data Source
  KAKENHI-PROJECT-19590693
[Presentation] ナトリウム利尿ポリペプチド製剤による肝線維化抑制効果についての検討2008
- Author(s)
  山本直樹
- Organizer
  第44回日本肝臓学会総会
- Place of Presentation
  愛媛
- Data Source
  KAKENHI-PROJECT-19790486
[Presentation] GFP/CCl4モデルにおける微細構造解析からの骨髄中の肝幹細胞の動態解析2008
- Author(s)
  山本直樹
- Organizer
  第44回日本肝臓学会総会
- Place of Presentation
  愛媛
- Year and Date
  2008-06-04
- Data Source
  KAKENHI-PROJECT-19790486
[Presentation] ABMI therapy combined with splenectomy is an effective for liver cirrhosis2008
- Author(s)
  Iwamoto T, Terai S, Yamamoto N, Sakaida I
- Organizer
  第59回AASLD(The American Association for the Study of Liver Disease)
- Place of Presentation
  San Francisco USA
- Year and Date
  2008-11-01
- Data Source
  KAKENHI-PROJECT-19390199
[Presentation] GFP/CCl4モデルにおける微細構造解析からの骨髄中の肝幹細胞の動態解析2008
- Author(s)
  山本直樹寺井崇二坂井田功
- Organizer
  第44回日本肝臓学会総会
- Place of Presentation
  愛媛
- Year and Date
  2008-06-04
- Data Source
  KAKENHI-PROJECT-19390199
[Presentation] 大柴胡湯のコリン欠乏性ラット肝硬変モデルに対する肝線維化・肝発癌抑制効果についての検討2008
- Author(s)
  内田耕一、山本直樹、寺井崇二、水永裕子、岩本拓也、桑代紳哉、坂井田功
- Organizer
  第59回アメリカ肝臓病学会(AASLD)
- Place of Presentation
  米国、サンフランシスコ
- Year and Date
  2008-11-03
- Data Source
  KAKENHI-PROJECT-19590693
[Presentation] GFP/CC14モデルにおける微細構造解析からの骨髄中の肝幹細胞の動態2008
- Author(s)
  山本直樹
- Organizer
  第44回日本肝臓学会総会
- Place of Presentation
  愛媛
- Data Source
  KAKENHI-PROJECT-19390199
[Presentation] Natriuretic peptide improved liver fibrosis in rat model using new treatment system2008
- Author(s)
  Yamamoto Naoki
- Organizer
  59^<th> AASLD 2008
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-19790486
[Presentation] G-CSF is a candidate serum marker for ABMI therapy for liver cirrhosis patient2008
- Author(s)
  Mizunaga Y, Terai S, Yamamoto N, Sakaida I
- Organizer
  第59回AASLD(The American Association for the Study of Liver Disease)
- Place of Presentation
  San Francisco USA
- Year and Date
  2008-11-01
- Data Source
  KAKENHI-PROJECT-19390199
[Presentation] GFP/CCl4モデルにおける微細構造解析からの骨髄中の肝幹細胞の動態解析2007
- Author(s)
  山本直樹寺井崇二坂井田功
- Organizer
  第43回日本肝臓学会総会
- Place of Presentation
  東京
- Year and Date
  2007-06-04
- Data Source
  KAKENHI-PROJECT-19390199
[Presentation] The American Association for the Study of Liver Disease2007
- Author(s)
  Terai S, Iwamoto T, Mizunaga Y, Omori K, Yamamoto N, Uchida K, Yamasaki T, Sakaida I
- Organizer
  第58回AASLD
- Place of Presentation
  Boston USA
- Year and Date
  2007-11-01
- Data Source
  KAKENHI-PROJECT-19390199
[Presentation] GFP/CCl4モデルにおける微細構造解析からの骨髄中の肝幹細胞の動態解析2007
- Author(s)
  山本直樹寺井崇二坂井田功
- Organizer
  第6回日本再生医療学会総会
- Place of Presentation
  横浜
- Year and Date
  2007-04-04
- Data Source
  KAKENHI-PROJECT-19390199
[Presentation] GFP/CC14モデルにおける微細構造解析からの骨髄中の肝幹細胞の動態解析2007
- Author(s)
  山本直樹
- Organizer
  第21回肝類洞壁細胞研究会
- Place of Presentation
  愛媛
- Year and Date
  2007-12-23
- Data Source
  KAKENHI-PROJECT-19790486
[Presentation] Natriuretic peptide improved liver fibrosis in rat model using new treatment system.2007
- Author(s)
  山本直樹
- Organizer
  第57回AASLD(The American Association for the Study of Liver Disease)
- Place of Presentation
  Boston USA
- Year and Date
  2007-11-04
- Data Source
  KAKENHI-PROJECT-19790486
[Presentation] GFP/CC14モデルにおける微細構造解析からの骨髄中の肝幹細胞の動態解析2007
- Author(s)
  山本直樹
- Organizer
  第6回日本再生医療学会総会
- Place of Presentation
  横浜
- Year and Date
  2007-03-05
- Data Source
  KAKENHI-PROJECT-19790486
[Presentation] GFP/CC14モデルにおける微細構造解析からの骨髄中の肝幹細胞の動態解析2007
- Author(s)
  山本直樹
- Organizer
  第14回肝細胞研究会
- Place of Presentation
  鹿児島
- Year and Date
  2007-06-23
- Data Source
  KAKENHI-PROJECT-19790486
[Presentation] GFP/CCl4モデルにおける微細構造解析からの骨髄中の肝幹細胞の動態解析2007
- Author(s)
  山本直樹
- Organizer
  第43回日本肝臓学会総会
- Place of Presentation
  東京
- Year and Date
  2007-06-04
- Data Source
  KAKENHI-PROJECT-19790486
[Presentation] ナトリウム利尿ポリペプチド製剤による肝線維化抑制効果についての検討2007
- Author(s)
  山本直樹
- Organizer
  第14回肝細胞研究会
- Place of Presentation
  鹿児島
- Year and Date
  2007-06-22
- Data Source
  KAKENHI-PROJECT-19790486
[Presentation] GFP/CC14モデルにおける微細構造解析からの骨髄中の肝幹細胞の動態解析2007
- Author(s)
  山本直樹
- Organizer
  第43回日本肝臓学会総会
- Place of Presentation
  東京
- Year and Date
  2007-06-04
- Data Source
  KAKENHI-PROJECT-19790486
[Presentation] Atrial natriuretic peptide (ANP) prevented liver fibrosis in rat using new treatment system2007
- Author(s)
  山本直樹
- Organizer
  第57回AASLD(The American Association for the study of Liver Disease)
- Place of Presentation
  Boston USA
- Year and Date
  2007-11-05
- Data Source
  KAKENHI-PROJECT-19790486
[Presentation] GFP/CCl4モデルにおける微細構造解析からの骨髄中の肝幹細胞の動態解析2007
- Author(s)
  山本直樹
- Organizer
  第14回肝細胞研究会
- Place of Presentation
  鹿児島
- Year and Date
  2007-06-20
- Data Source
  KAKENHI-PROJECT-19790486
[Presentation] GFP/CCl4モデルにおける微細構造解析からの骨髄中の肝幹細胞の動態解析2007
- Author(s)
  山本直樹
- Organizer
  第6回日本再生医療学会総会
- Place of Presentation
  横浜
- Year and Date
  2007-04-04
- Data Source
  KAKENHI-PROJECT-19790486
[Presentation] ナトリウム利尿ポリペプチド製剤による肝線維化抑制効果についての検討2007
- Author(s)
  山本直樹
- Organizer
  第43回日本肝臓学会総会
- Place of Presentation
  東京
- Year and Date
  2007-06-04
- Data Source
  KAKENHI-PROJECT-19790486
[Presentation] GFP/CCl4モデルにおける微細構造解析からの骨髄中の肝幹細胞の動態解析2007
- Author(s)
  山本直樹寺井崇二坂井田功
- Organizer
  第14回肝細胞研究会
- Place of Presentation
  鹿児島
- Year and Date
  2007-06-20
- Data Source
  KAKENHI-PROJECT-19390199
[Presentation] New canine liver cirrhotic model to develop a less invasive regeneration therapy using cultured autologous bone marrow-derived cells
- Author(s)
  Takashi Matsuda, Taro Takami, Tsuyoshi Ishikawa, Naoki Yamamoto, Shuji Terai, Isao Sakaida
- Organizer
  The Liver Meeting 2014, AASLD
- Place of Presentation
  John B. Hynes Veterans Memorial Convention Center（Boston USA)
- Year and Date
  2014-11-07 – 2014-11-11
- Data Source
  KAKENHI-PROJECT-24590978
[Presentation] 次世代型経口鉄キレート剤は再発予防剤およびソラフェニブの副作用軽減剤となりうる
- Author(s)
  山本直樹、山崎隆弘、佐伯　一成、高見太郎、藤澤浩一、内田耕一、寺井崇二、坂井田功
- Organizer
  第50回日本肝臓学会総会
- Place of Presentation
  ホテルニューオータニ　(東京）
- Year and Date
  2014-05-29 – 2014-05-30
- Data Source
  KAKENHI-PROJECT-24590978
[Presentation] 骨髄由来及び脂肪組織由来間葉系幹細胞(BMSC・ASC)における生物学的特性の差異に関する検討
- Author(s)
  白築祥吾, 寺井崇二, 村田泰彦, 松田崇史石川剛, 高見太郎, 山本直樹, 坂井田功
- Organizer
  第50回日本肝臓学会総会
- Place of Presentation
  ホテルニューオータニ　(東京）
- Year and Date
  2014-05-29 – 2014-05-30
- Data Source
  KAKENHI-PROJECT-24590978
[Presentation] 肝臓線維化における骨髄由来肝臓修復細胞の特徴
- Author(s)
  山本　直樹　高見　太郎　藤澤　浩一　寺井　崇二　坂井田　功
- Organizer
  第14回日本再生医療学会総会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市）
- Year and Date
  2015-03-19 – 2015-03-21
- Data Source
  KAKENHI-PROJECT-24590978
[Presentation] Less invasive liver regeneration therapy for liver cirrhosis using cultured autologous bone marrow-derived mesenchymal stem cells.
- Author(s)
  Takami T, Terai S, Quintanilha LF, Fujisawa K, Yamamoto N, Sakaida I.
- Organizer
  FASEB meeting
- Place of Presentation
  Keystone, CO, USA
- Year and Date
  2014-07-06 – 2014-07-10
- Data Source
  KAKENHI-PROJECT-26461009
[Presentation] 培養骨髄間葉系幹細胞投与による肝臓再生メカニズムの解明
- Author(s)
  高見　太郎　藤澤　浩一　山本　直樹　寺井　崇二　坂井田　功
- Organizer
  第14回日本再生医療学会総会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市）
- Year and Date
  2015-03-19 – 2015-03-21
- Data Source
  KAKENHI-PROJECT-24590978
[Presentation] Our regeneration therapies using autologous bone marrow cells for liver cirrhosis.
- Author(s)
  Taro Takami, Shuji Terai, Bruno Diaz Paredes, Luiz Fernando Quintanilha, Koichi Fujisawa, Naoki Yamamoto, Isao Sakaida
- Organizer
  JDDW 2014 International Session (Symposium)
- Place of Presentation
  神戸国際会議場(兵庫県神戸市）
- Year and Date
  2014-10-23 – 2014-10-26
- Data Source
  KAKENHI-PROJECT-24590978
[Presentation] 培養自己骨髄間葉系幹細胞投与の安全性・有効性および投与経路評価のためのイヌ肝線維化モデル
- Author(s)
  松田　崇史、高見　太郎、石川　剛、山本　直樹、寺井　崇二、坂井田　功
- Organizer
  第50回日本肝臓学会総会
- Place of Presentation
  ホテルニューオータニ　(東京）
- Year and Date
  2014-05-29 – 2014-05-30
- Data Source
  KAKENHI-PROJECT-24590978
[Presentation] Less invasive liver regeneration therapy for liver cirrhosis using cultured autologous bone marrow-derived mesenchymal stem cells with redox-regulatory capacity.
- Author(s)
  Takami T, Terai S, Paredes BD, Quintanilha LF, Fujisawa K, Yamamoto N, Sakaida I.
- Organizer
  The Liver meeting 2014, AASLD
- Place of Presentation
  Boston, MA, USA
- Year and Date
  2014-11-07 – 2014-11-11
- Data Source
  KAKENHI-PROJECT-26461009

1. TAKAMI Taro (60511251)

# of Collaborated Projects: 27 results

# of Collaborated Products: 134 results
2. FUJISAWA Koichi (00448284)

# of Collaborated Projects: 20 results

# of Collaborated Products: 111 results
3. TERAI Shuji (00332809)

# of Collaborated Projects: 14 results

# of Collaborated Products: 70 results
4. SAKAIDA Isao (80263763)

# of Collaborated Projects: 12 results

# of Collaborated Products: 66 results
5. 松本俊彦 (70634723)

# of Collaborated Projects: 12 results

# of Collaborated Products: 88 results
6. UCHIDA Koichi (80397992)

# of Collaborated Projects: 4 results

# of Collaborated Products: 7 results
7. YAMASAKI Takahiro (00304478)

# of Collaborated Projects: 4 results

# of Collaborated Products: 20 results
8. TANI KENJI (00365420)

# of Collaborated Projects: 4 results

# of Collaborated Products: 5 results
9. HASHIMOTO Shinichi (40530217)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
10. IIZUKA Norio (80332807)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. ISHIKAWA Tsuyoshi (20569305)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
12. Kamimura Kenya (00579146)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
13. TAURA YASUHO (80163153)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. MIYATA Hirofumi (90190793)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 仲澤宏 (90604992)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 山際訓 (10419327)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 佐藤祐一 (00401761)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 川合弘一 (80419291)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 土屋淳紀 (70464005)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 岩本拓也 (80634716)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 佐伯一成 (60634756)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
22. 砂原央 (20836209)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 山本健 (50363122)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
24. 河井一明 (60161262)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 李云善 (90449950)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. NISHINA Hiroshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. TABATA Yasuhiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. TOGUCHIDA Junya

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. AIBE Yuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
30. YONEDA Kenji

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Yamamoto Naoki 山本 直樹

YAMAMOTO Naoki 山本 直樹

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The cell identification research of bone marrow drived liver repaired cell in the new liver regeneration therapyPrincipal Investigator

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二種類の骨髄由来肝臓修復細胞による効率的な肝臓再生療法の開発Principal Investigator

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Yamamoto Naoki 山本直樹

YAMAMOTO Naoki 山本直樹