KIYAMA Yuji 城山優治

… Alternative Names

Kiyama Yuji 城山優治

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Researcher Number	90456195
Other IDs
Affiliation (Current)	2025: 鹿児島大学, 医歯学域医学系, 助教
Affiliation (based on the past Project Information) *help	2019 – 2024: 鹿児島大学, 医歯学域医学系, 助教 2017 – 2018: 東京大学, 先端科学技術研究センター, 特任助教 2015 – 2016: 東京大学, 医科学研究所, 助教 2009 – 2013: The University of Tokyo, 医科学研究所, 助教
Review Section/Research Field	Principal Investigator Basic Section 51020:Cognitive and brain science-related / Brain biometrics / Fusional basic brain science / Laboratory animal science Except Principal Investigator Basic Section 55060:Emergency medicine-related / Basic Section 46010:Neuroscience-general-related
Keywords	Principal Investigator 扁桃体 / 情動 / 恐怖 / GRP / 光操作 / 神経活動操作 / 拘束ストレス / 恐怖学習 / AST / ストレス … More / Arc / 恐怖条件付け / arc promoter / amygdala / Venus / Arc promoter / 透明化 / 遺伝子改変動物 / 活動神経 / ドミナント・ネガティブ / PhiC31o / 部位特異的遺伝子欠損 / dominant negative / hyperactive / dominant-negative / Amygdala / Cre recombinase / プロモーター / Cre-loxPシステム / シナプス可塑性 / 不安 / NMDA受容体 / miRNA … More Except Principal Investigator 神経活動イメージング / 敗血症関連脳症 / 鎮静薬 / 神経イメージング / 敗血症性脳症 / 敗血症 / パルミトイル化酵素 / 神経活動依存的遺伝子 / ZDHHC18 / 遺伝子欠損マウス / Zdhhc18 / 活動依存的 / 統合失調症 / 神経活動依存的 / zdhhc18 Less

敗血症脳症に伴う特異的脳神経活動の機能的意義
- Principal Investigator
  
  中原真由美
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Kagoshima University
In vitro, in vivo functions and involvement in schizophrenia of lipid modifying enzyme that shows activity-dependent expression
- Principal Investigator
  
  Haraguchi Misako
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 46010:Neuroscience-general-related
- Research Institution
  Kagoshima University
インビボ神経イメージングによる敗血症関連脳症に関与する大脳神経回路同定と治療戦略
- Principal Investigator
  
  中原真由美
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Kagoshima University
Neuronal networks regulating emotional conditions under stressed conditionsPrincipal Investigator
- Principal Investigator
  
  KIYAMA YUJI
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51020:Cognitive and brain science-related
- Research Institution
  Kagoshima University
Functional Analysis of Amygdaloid Nucleus by Profiling Activated NeuronsPrincipal Investigator
- Principal Investigator
  
  Kiyama Yuji
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Brain biometrics
- Research Institution
  The University of Tokyo
Creation and analysis of amygdala-specific gene knockout mice utilizing a dominant-negative mutant of CrePrincipal Investigator
- Principal Investigator
  
  KIYAMA Yuji
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Fusional basic brain science
- Research Institution
  The University of Tokyo
Establishment of a technique to generate highly brain region specific gene knockdown mouse and its applicationPrincipal Investigator
- Principal Investigator
  
  KIYAMA Yuji
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research a proposed research project)
- Research Field
  
  Laboratory animal science
- Research Institution
  The University of Tokyo

All 2022 2021 2019 2018 2016 2014 2013 2012 2011 Other

All Journal Article Presentation Other

[Journal Article] Loss of calsyntenin paralogs disrupts interneuron stability and mouse behavior2022
- Author(s)
  Mori Keita、Koebis Michinori、Nakao Kazuki、Kobayashi Shizuka、Kiyama Yuji、Watanabe Masahiko、Manabe Toshiya、Iino Yuichi、Aiba Atsu
- Journal Title
  
  Molecular Brain
  
  Volume: 15 Issue: 1 Pages: 23-23
- DOI
  10.1186/s13041-022-00909-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06901, KAKENHI-PROJECT-19K07799, KAKENHI-PROJECT-19H03321, KAKENHI-PROJECT-17H06113
[Journal Article] Gastrin-releasing peptide regulates fear learning under stressed conditions via activation of the amygdalostriatal transition area2022
- Author(s)
  Goto Fumiko、Kiyama Yuji、Ogawa Itone、Okuno Hiroyuki、Ichise Taeko、Ichise Hirotake、Anai Motonobu、Kodama Tatsuhiko、Yoshida Nobuaki、Bito Haruhiko、Manabe Toshiya
- Journal Title
  
  Molecular Psychiatry
  
  Volume: - Issue: 3 Pages: 1694-1703
- DOI
  10.1038/s41380-021-01408-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07799, KAKENHI-PUBLICLY-20H05068, KAKENHI-PROJECT-19H03321, KAKENHI-PROJECT-19H03328, KAKENHI-ORGANIZER-17H06308, KAKENHI-PLANNED-17H06312
[Journal Article] Cooperation of LIM domain-binding 2 (LDB2) with EGR in the pathogenesis of schizophrenia.2021
- Author(s)
  Ohnishi T, Kiyama Y, Arima-Yoshida F, Kadota M, Ichikawa T, Yamada K, Watanabe A, Ohba H, Tanaka K, Nakaya A, Horiuchi Y, Iwayama Y, Toyoshima M, Ogawa I, Shimamoto-Mitsuyama C, Maekawa M, Balan S, Arai M, Miyashita M, Toriumi K, et al.
- Journal Title
  
  EMBO Mol Med
  
  Volume: 13 Issue: 4
- DOI
  10.15252/emmm.202012574
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06977, KAKENHI-PROJECT-19K07799, KAKENHI-PROJECT-19K08023, KAKENHI-PROJECT-20K07934, KAKENHI-PUBLICLY-19H04876, KAKENHI-PUBLICLY-19H04887, KAKENHI-PROJECT-19H03328, KAKENHI-PROJECT-19H03589, KAKENHI-PROJECT-19H03321, KAKENHI-PROJECT-19K06629, KAKENHI-PROJECT-18H03579, KAKENHI-PROJECT-18K07578
[Journal Article] Glial pathology in a novel spontaneous mutant mouse of the Eif2b5 gene: a vanishing white matter disease model.2019
- Author(s)
  Terumitsu-Tsujita M, Kitaura H, Miura I, Kiyama Y, Goto F, Muraki Y, Ominato S, Hara N, Simankova A, Bizen N, Kashiwagi K, Ito T, Toyoshima Y, Kakita A, Manabe T, Wakana S, Takebayashi H, Igarashi H
- Journal Title
  
  Ｊｏｕｒｎａｌ　ｏｆ　Ｎｅｕｒｏｃｈｅｍｉｓｔｒｙ
  
  Volume: jnc.14887 Issue: 1 Pages: 1-16
- DOI
  10.1111/jnc.14887
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07799, KAKENHI-PUBLICLY-18H04939, KAKENHI-PUBLICLY-19H04876, KAKENHI-PROJECT-19H03321, KAKENHI-PROJECT-17K15542, KAKENHI-PROJECT-18H02592
[Journal Article] The adhesion molecule cadherin 11 is essential for acquisition of normal hearing ability through middle ear development in the mouse2018
- Author(s)
  Kiyama Yuji、Kikkawa Yayoi S.、Kinoshita Makoto、Matsumoto Yu、Kondo Kenji、Fujimoto Chisato、Iwasaki Shinichi、Yamasoba Tatsuya、Manabe Toshiya
- Journal Title
  
  Laboratory Investigation
  
  Volume: 98 Issue: 11 Pages: 1364-1374
- DOI
  10.1038/s41374-018-0083-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17KT0048, KAKENHI-PROJECT-18K09341, KAKENHI-PROJECT-18K09369, KAKENHI-PROJECT-18K09370, KAKENHI-PROJECT-15K10744, KAKENHI-PROJECT-16K11226, KAKENHI-PROJECT-15K01848
[Journal Article] Lemur kinase 3 deficiency causes pronounced locomotor hyperactivity and impairs endocytic trafficking2014
- Author(s)
  Inoue T, Hoshina N, Nakazawa T, Kiyama Y, Kobayashi S, Abe T, Yamamoto T, Manabe T and Yamamoto T
- Journal Title
  
  J. Neurosci.
  
  Volume: 34 Pages: 5927-5937
- Data Source
  KAKENHI-PROJECT-23700488
[Journal Article] LMTK3 deficiency causes pronounced locomotor hyperactivity and impairs endocytic trafficking2014
- Author(s)
  Takeshi Inoue, Naosuke Hoshina, Takanobu Nakazawa, Yuji Kiyama, Shizuka Kobayashi, Takaya Abe, Toshifumi Yamamoto, Toshiya Manabe, and Tadashi Yamamoto
- Journal Title
  
  Journal of Neuroscience
  
  Volume: 未定
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23700488
[Journal Article] NMDAR2B tyrosine phosphorylation is involved in thermal nociception2012
- Author(s)
  Delawary M, Tezuka T, Yamamoto T. (9名)
- Journal Title
  
  Neurosci Lett
  
  Volume: Vol.516 Issue: 2 Pages: 270-273
- DOI
  10.1016/j.neulet.2012.04.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229006, KAKENHI-PROJECT-23220008, KAKENHI-PROJECT-23700488, KAKENHI-PLANNED-21115006, KAKENHI-PUBLICLY-24121705
[Journal Article] NMDAR2B tyrosine phosphorylation is involved in thermal nociception2012
- Author(s)
  Delawary M., Tezuka T., Kiyama Y., Yokoyama K., Wada E., Wada K., Manabe T., Yamamoto T., Nakazawa T.
- Journal Title
  
  Neurosci. Lett.
  
  Volume: 516(2) Pages: 270-273
- Data Source
  KAKENHI-PROJECT-23700488
[Journal Article] Age-dependent regulation of depression-like behaviors through modulation of adrenergic receptor α1A subtype expression revealed by the analysis of interleukin-1 receptor antagonist knockout mice2011
- Author(s)
  Wakabayashi C., Kiyama Y., Kunugi H., Manabe T., Iwakura Y.
- Journal Title
  
  Neuroscience
  
  Volume: 192 Pages: 475-484
- Data Source
  KAKENHI-PROJECT-23700488
[Presentation] Ldb2 modulates neuronal activities and fear learning by regulating Arc expression in the lateral nucleus of the amygdala2022
- Author(s)
  城山優治
- Organizer
  第44回日本神経科学大会/第1回 CJK 国際会議
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07799
[Presentation] 術後認知機能障害(POCD)マウスモデルの開発と術後認知機能障害関連脳領域の同定2021
- Author(s)
  大江将軍、長谷川麻衣子、向原桂香、中原真由美、城山優治、奥野浩行、森山孝宏、上村裕一
- Organizer
  第62回日本麻酔科学会
- Data Source
  KAKENHI-PROJECT-21K09077
[Presentation] マウスにおける全身麻酔下手術による扁桃体の神経活動亢進と記憶障害2021
- Author(s)
  城山優治、中原真由美、大江将軍、坂口茜、黒江那彩、上村裕一、奥野浩行
- Organizer
  第93回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K07799
[Presentation] てんかん発症に至るまでの海馬歯状回　（APE欠損をモデルとして）2019
- Author(s)
  城山優治、奥野浩行、内藤眞、尾藤晴彦、児玉龍彦、真鍋俊也、穴井元暢
- Organizer
  日本生化学会第92回大会
- Data Source
  KAKENHI-PROJECT-19K07799
[Presentation] GRP regulates fear learning under stress conditions2016
- Author(s)
  後藤史子、城山優治、　小川糸音、奥野浩行、吉田進昭、尾藤晴彦、真鍋俊也
- Organizer
  日本神経科学学会大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-15K01848
[Presentation] The adhesion molecule cadherin 11 is essential for acquiring normal hearing ability2013
- Author(s)
  城山優治
- Organizer
  東京大学生命科学シンポジウム
- Place of Presentation
  東京大学伊藤国際学術研究センター
- Data Source
  KAKENHI-PROJECT-23700488
[Presentation] 細胞接着分子cadherin 11は正常な聴覚機能獲得に必須である2012
- Author(s)
  城山優治　吉川弥生　竹市雅俊　山岨達也　真鍋俊也
- Organizer
  第３５回日本分子生物学会大会
- Place of Presentation
  マリンメッセ福岡（福岡）
- Data Source
  KAKENHI-PROJECT-23700488
[Presentation] 細胞接着因子Cadherin11は正常な聴覚機能獲得に必須である2012
- Author(s)
  城山優治、吉川弥生、竹市雅俊、山岨達也、真鍋俊也
- Organizer
  第35回日本分子生物学会退会
- Place of Presentation
  マリンメッセ福岡(福岡市)
- Data Source
  KAKENHI-PROJECT-23700488
[]
[]

1. 奥野浩行 (80272417)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
2. 中原真由美 (90707514)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. Haraguchi Misako (10244229)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 新山修平 (40258455)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. OGAWA Itone

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. TORIUMI Kazuya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. MATSUMOTO Yu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 山本雅

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 小林静香

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KIYAMA Yuji 城山 優治

Kiyama Yuji 城山 優治

Research Projects

Research Products

Co-Researchers

敗血症脳症に伴う特異的脳神経活動の機能的意義

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

In vitro, in vivo functions and involvement in schizophrenia of lipid modifying enzyme that shows activity-dependent expression

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

インビボ神経イメージングによる敗血症関連脳症に関与する大脳神経回路同定と治療戦略

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Neuronal networks regulating emotional conditions under stressed conditionsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functional Analysis of Amygdaloid Nucleus by Profiling Activated NeuronsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Creation and analysis of amygdala-specific gene knockout mice utilizing a dominant-negative mutant of CrePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of a technique to generate highly brain region specific gene knockdown mouse and its applicationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Loss of calsyntenin paralogs disrupts interneuron stability and mouse behavior2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Gastrin-releasing peptide regulates fear learning under stressed conditions via activation of the amygdalostriatal transition area2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cooperation of LIM domain-binding 2 (LDB2) with EGR in the pathogenesis of schizophrenia.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Glial pathology in a novel spontaneous mutant mouse of the Eif2b5 gene: a vanishing white matter disease model.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The adhesion molecule cadherin 11 is essential for acquisition of normal hearing ability through middle ear development in the mouse2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Lemur kinase 3 deficiency causes pronounced locomotor hyperactivity and impairs endocytic trafficking2014

Author(s)

Journal Title

Data Source

[Journal Article] LMTK3 deficiency causes pronounced locomotor hyperactivity and impairs endocytic trafficking2014

Author(s)

Journal Title

Data Source

KIYAMA Yuji 城山優治

Kiyama Yuji 城山優治

[Presentation] てんかん発症に至るまでの海馬歯状回　（APE欠損をモデルとして）2019