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Yoshihara Satoshi  吉原 哲

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YOSHIHARA Satoshi  吉原 哲

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Researcher Number 90461037
Other IDs
Affiliation (Current) 2025: 兵庫医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help 2024: 兵庫医科大学, 医学部, 教授
2016 – 2019: 兵庫医科大学, 医学部, 講師
2017: 兵庫医科大学, 医学部, 助教
2009 – 2011: 兵庫医科大学, 医学部, 助教
Review Section/Research Field
Principal Investigator
Basic Section 50020:Tumor diagnostics and therapeutics-related / Laboratory animal science
Except Principal Investigator
Basic Section 53020:Cardiology-related / Basic Section 49020:Human pathology-related / Tumor therapeutics / Hematology
Keywords
Principal Investigator
多発性骨髄腫 / CAR-T細胞療法 / 免疫療法 / ヒト化マウス / 間葉系細胞 / 間葉系幹細胞
Except Principal Investigator
キメラ抗原受容体T細胞療法 / 腫瘍循環器 / びまん性大細胞型B細胞リンパ腫 / 遷延性血球減少 … More / 血球減少 / CAR-T細胞療法 / CAR-T細胞 / 生着促進 / 骨髄内移植 / 骨髄内臍帯血移植 / 間葉系幹細胞 / 臍帯血移植 / 移植片対宿主病 / HLA不適合移植 / 造血幹細胞移植 Less
  • Research Projects

    (6 results)
  • Research Products

    (35 results)
  • Co-Researchers

    (14 People)
  •  Clinicopathological analysis of prolonged cytopenia after chimeric antigen receptor (CAR)-T cell therapy

    • Principal Investigator
      松田 育雄
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49020:Human pathology-related
    • Research Institution
      Hyogo Medical University
  •  キメラ抗原受容体T細胞療法における標的抗原以外に対する免疫応答の意義Principal Investigator

    • Principal Investigator
      吉原 哲
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Hyogo Medical University
  •  非ホジキンリンパ腫患者のキメラ抗原受容体T細胞療法前後における心機能の経時的変化

    • Principal Investigator
      大星 真貴子
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Hyogo Medical University
  •  An immunotherapy model for hematopoietic malignancies (multiple myeloma) using humanized micePrincipal Investigator

    • Principal Investigator
      Yoshihara Satoshi
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory animal science
    • Research Institution
      Hyogo Medical University
  •  Novel therapeutic strategy by intrabone marrow co-transplantation of cord blood and cord-derived mesenchymal stem cells

    • Principal Investigator
      OKADA Masaya
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Tumor therapeutics
    • Research Institution
      Hyogo Medical University
  •  Establishment of safety of HLA-haploidentical stem cell transplantation

    • Principal Investigator
      OGAWA Hiroyasu
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Hyogo Medical University

All 2020 2019 2018 2017 2012 2011 2010 2009

All Journal Article Presentation

  • [Journal Article] Treatment strategy in a patient showing borderline features between plasmablastic lymphoma and plasmablastic myeloma harboring a 17p deletion2020

    • Author(s)
      Yoshihara Kyoko、Yoshihara Satoshi、Matsuda Ikuo、Imado Takehito、Matsuo Shohei、Okada Masaya、Shimizu Yoshifumi、Hirota Seiichi、Fujimori Yoshihiro
    • Journal Title

      Annals of Hematology

      Volume: 99 Issue: 6 Pages: 1405-1407

    • DOI

      10.1007/s00277-020-03975-x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K07142
  • [Journal Article] Safety and efficacy of amnion-derived mesenchymal stem cells (AM01) in patients with steroid-refractory acute graft-versus-host disease after allogeneic haematopoietic stem cell transplantation: a study protocol for a phase I/II Japanese trial2019

    • Author(s)
      Yamahara K、Hamada A、Soma T、Okamoto R、Okada M、Yoshihara S、Yoshihara K、Ikegame K、Tamaki H、Kaida K、Inoue T、Ohsugi Y、Nishikawa H、Hayashi H、Ito Y、Iijima H、Ohnishi S、Hashimoto D、Isoe T、Teshima T、Ogawa H、Sato N、Fujimori Y
    • Journal Title

      BMJ Open

      Volume: 9 Issue: 7 Pages: e026403-e026403

    • DOI

      10.1136/bmjopen-2018-026403

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K07142, KAKENHI-PROJECT-17K07228
  • [Journal Article] Predictive value of interim FDG-PET/CT findings in patients with diffuse large B-cell lymphoma treated with R-CHOP2019

    • Author(s)
      Kitajima Kazuhiro、Okada Masaya、Yoshihara Kyoko、Tokugawa Tazuko、Sawada Akihiro、Yoshihara Satoshi、Tamaki Hiroya、Fujimori Yoshihiro、Ueda Syuji、Kawamoto Hiroyuki、Taniguchi Junichi、Yamakado Koichiro
    • Journal Title

      Oncotarget

      Volume: 10 Issue: 52 Pages: 5403-5411

    • DOI

      10.18632/oncotarget.27103

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K07142
  • [Journal Article] Low incidence of HHV‐6 reactivation in haploidentical hematopoietic stem cell transplantation with corticosteroid as graft‐vs‐host disease prophylaxis compared with cord blood transplantation2019

    • Author(s)
      Tamaki Hiroya、Ikegame Kazuhiro、Yoshihara Satoshi、Kaida Katsuji、Yoshihara Kyoko、Inoue Takayuki、Kato Ruri、Nakata Jun、Fujioka Tatsuya、Soma Toshihiro、Okada Masaya、Ogawa Hiroyasu
    • Journal Title

      Transplant Infectious Disease

      Volume: - Issue: 3

    • DOI

      10.1111/tid.13073

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K07185, KAKENHI-PROJECT-16K09882, KAKENHI-PROJECT-17K07142
  • [Journal Article] Early evaluation of tumor response to 90Y-ibritumomab radioimmunotherapy in relapsed/refractory B cell non-Hodgkin lymphoma: what is the optimal timing for FDG-PET/CT?2019

    • Author(s)
      Kitajima K, Okada M, et al.
    • Journal Title

      Eur Radiol.

      Volume: - Issue: 7 Pages: 3935-3944

    • DOI

      10.1007/s00330-019-06134-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K07185, KAKENHI-PROJECT-17K07142
  • [Journal Article] Posttransplant Hemophagocytic Lymphohistiocytosis Driven by Myeloid Cytokines and Vicious Cycles of T-Cell and Macrophage Activation in Humanized Mice2019

    • Author(s)
      Yoshihara Satoshi、Li Yuying、Xia Jinxing、Danzl Nichole、Sykes Megan、Yang Yong-Guang
    • Journal Title

      Frontiers in Immunology

      Volume: 10

    • DOI

      10.3389/fimmu.2019.00186

    • Data Source
      KAKENHI-PROJECT-17K07142
  • [Journal Article] A prospective multicenter phase II study of intrabone marrow transplantation of unwashed cord blood using reduced-intensity conditioning.2018

    • Author(s)
      Okada M, Tasaka T, et al.
    • Journal Title

      Eur J Haematol.

      Volume: 100 Issue: 4 Pages: 335-343

    • DOI

      10.1111/ejh.12999

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K07185, KAKENHI-PROJECT-17K07142
  • [Journal Article] 急性GVHD・クローン病に対する羊膜由来間葉系幹細胞の医師主導治験 -兵庫医科大学発・初認定ベンチャーによる開発をめざして-2018

    • Author(s)
      山原 研一, 濱田 彰子, 大西 俊介, 相馬 俊裕, 岡本 里香, 中村 志郎, 岡田 昌也, 吉原 哲, 吉原 享子, 橋本 大吾, 磯江 敏幸, 豊嶋 崇徳, 佐藤 典宏, 藤盛 好啓
    • Journal Title

      兵庫医科大学医学会雑誌

      Volume: 43 Pages: 41-45

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K07185
  • [Journal Article] Aldehyde dehydrogenase activity in cryopreserved cord blood cells for quality assessment prior to transplantation2018

    • Author(s)
      Ikemoto Junko、Yoshihara Satoshi、Kobayashi Tamami、Kai Shunro、Fujimori Yoshihiro
    • Journal Title

      Molecular Medicine Reports

      Volume: 18 Pages: 4530-4534

    • DOI

      10.3892/mmr.2018.9481

    • Data Source
      KAKENHI-PROJECT-17K07142
  • [Journal Article] Intra-bone marrow transplantation of unwashed cord blood using reduced-intensity conditioning treatment : A phase I study2012

    • Author(s)
      Okada M, Yoshihara S, Taniguchi K, Ogawa H, et al.(12人中12番)
    • Journal Title

      Biology of Blood and Marrow Transplantation

      Volume: 18 Issue: 4 Pages: 633-639

    • DOI

      10.1016/j.bbmt.2008.12.508

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591252
  • [Journal Article] Salvage haploidentical transplantation for graft failure using reduced-intensity conditioning2012

    • Author(s)
      Yoshihara S, Ikegame K, Taniguchi K, Ogawa H, et al.(13人中13番)
    • Journal Title

      Bone Marrow Transplantation

      Volume: 47 Issue: 3 Pages: 369-373

    • DOI

      10.1038/bmt.2011.84

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591252
  • [Journal Article] Risk and prevention of graft failure in patients with preexisting donor-specific HLA antibodies undergoing unmanipulated haploidentical SCT2011

    • Author(s)
      Yoshihara S, Maruya E, Taniguchi K, Ogawa H. et al.(17人中17番)
    • Journal Title

      Bone Marrow Transplantation

      Volume: (in press) Issue: 4 Pages: 508-515

    • DOI

      10.1038/bmt.2011.131

    • Year and Date
      2011-06-20
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591252
  • [Journal Article] Strategy for bone marrow transplantation in eculizumab-treated paroxysmal nocturnal hemoglobinuria2011

    • Author(s)
      Taniguchi K, Okada M, Yoshihara S, Ogawa H, et al.(11人中11番)
    • Journal Title

      International Journal of Hematology

      Volume: 94 Issue: 4 Pages: 403-407

    • DOI

      10.1007/s12185-011-0931-7

    • NAID

      10030265488

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591252
  • [Journal Article] Incidence of extramedullary relapse after haploidentical SCT for advanced AML/myelodysplastic syndrome2011

    • Author(s)
      Yoshihara S, Ikegame K, Kaida K, Ogawa H, et al.(11人中11番)
    • Journal Title

      Bone Marrow Transplantation

      Volume: (in press) Issue: 5 Pages: 669-676

    • DOI

      10.1038/bmt.2011.163

    • Year and Date
      2011-08-22
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591252
  • [Journal Article] Allogeneic stem cell transplantation as treatment for heavily-treated, refractory acute graft-versus-host disease after HLA-mismatched stem cell transplantation2011

    • Author(s)
      Ikegame K, Yoshihara S, Taniguchi Y, Ogawa H, et al.(13人中13番)
    • Journal Title

      Experimental Hematology

      Volume: 39 Issue: 8 Pages: 880-890

    • DOI

      10.1016/j.exphem.2011.05.007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591252
  • [Journal Article] Use of foscarnet for cytomegalovirus infection after allogeneic hematopoietic stem cell transplantation from a related donor2010

    • Author(s)
      Asakura M, Ikegame K, Yoshihara S, Ogawa H. et al.(16人中16番)
    • Journal Title

      International Journal of Hematology

      Volume: 92 Issue: 2 Pages: 351-359

    • DOI

      10.1007/s12185-010-0657-y

    • NAID

      10026712482

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591252
  • [Journal Article] Molecular detection of AML1-MTG8-positive cells in peripheral blood from a patient with isolated extramedullary relapse of t(8 ; 21) acute myeloid leukemia2009

    • Author(s)
      Tamaki H, Yoshihara S, Fujioka T, Ogawa H, et al.(6人中6番)
    • Journal Title

      Leukemia

      Volume: 23 Issue: 2 Pages: 424-426

    • DOI

      10.1038/leu.2008.220

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591252
  • [Presentation] Feasibility of 6 cycles of VRd/KRd as induction therapy prior to stem-cell collection in transplant-eligible multiple myeloma.2020

    • Author(s)
      Yoshihara Kyoko, Shimizu Yoshifumi, Yoshihara Satoshi, Takatsuka Hiroyuki, Kawamoto Hiroyuki, Imado Takehito, Okada Masaya, Fujimori Yoshihiro
    • Organizer
      第42回造血細胞移植学会総会
    • Data Source
      KAKENHI-PROJECT-17K07142
  • [Presentation] 生物由来原料基準を満たす国産ウシ血小板溶解物「NeoSERA」を原材料とする羊膜由来間葉系幹細胞の細胞製剤化2019

    • Author(s)
      山原研一, 浜田彰子, 黒田将子, 池本純子, 吉原享子, 吉原哲, 岡田昌也, 橋本大吾, 相馬俊裕, 豊嶋崇徳, 藤盛好啓
    • Organizer
      第67回日本輸血・細胞治療学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K07142
  • [Presentation] DLBCL再発例の治療および予後に関する後方視的解析2019

    • Author(s)
      吉原享子, 清水義文, 高塚広行, 川本裕之, 吉原哲, 徳川多津子, 澤田暁宏, 玉置広哉, 岡田昌也, 三澤眞人, 伊福秀貴, 大江与喜子, 藤盛好啓.
    • Organizer
      第81回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K07142
  • [Presentation] Ph陽性ALL患者における移植後TKI維持療法の有用性2019

    • Author(s)
      福永景子, 池亀和博, 海田勝仁, 井上貴之, 吉原哲, 吉原享子, 大杉夕子, 玉置広哉, 岡田昌也, 小川啓恭, 藤盛好啓
    • Organizer
      第81回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K07142
  • [Presentation] Bendamustine plus rituximab in the treatment of indolentlymphoma.2018

    • Author(s)
      Yoshihara Kyoko, Shimizu Yoshifumi, Kawamoto Hiroyuki, Takatsuka Hiroyuki, Tokugawa Tazuko, Sawada Akihiro, Yoshihara Satoshi, Okada Masaya, Misawa Mahito, Ifuku Hidetaka, Okamoto Takahiro, Ooe Yokiko, Fujimori Yoshihiro
    • Organizer
      第80回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K07142
  • [Presentation] V-EPOCHが著効したdel 17pを有するplasmablastic lymphoma/myelomaの1例2018

    • Author(s)
      吉原享子、吉原哲、松田育雄、松尾祥平、今戸健一、岡田昌也、廣田誠一、藤盛好啓
    • Organizer
      第43回日本骨髄腫学会総会
    • Data Source
      KAKENHI-PROJECT-17K07142
  • [Presentation] 当院におけるテムセルHS注の運用2018

    • Author(s)
      池本純子、杉山寛貴、原田由紀、大塚真哉、小野本仁美、入江玲子、 奥田典子、村田理恵、前田和宏、吉原享子、吉原哲、岡田昌也、 山原研一、相馬俊裕、藤盛好啓
    • Organizer
      第40回日本造血細胞移植学会総会
    • Data Source
      KAKENHI-PROJECT-17K07142
  • [Presentation] IgA型M蛋白の急激な上昇を伴う骨髄再発を来した胸腺MALTリンパ腫の一例2018

    • Author(s)
      吉原哲 , 松田育雄, 吉原享子, 池本純子, 岡山昌也, 廣田誠一, 藤盛好啓
    • Organizer
      第58回日本リンパ網内系学会総会
    • Data Source
      KAKENHI-PROJECT-17K07142
  • [Presentation] Len/dexによる導入療法後に大量メルファラン療法+自家末梢血幹細胞移植を施行したPOEMS症候群の一例2018

    • Author(s)
      円山牧子, 吉原享子, 松田育雄, 吉原哲, 岡田昌也, 廣田誠一, 藤盛好啓
    • Organizer
      第58回日本リンパ網内系学会総会
    • Data Source
      KAKENHI-PROJECT-17K07142
  • [Presentation] V-EPOCHが著効したdel 17pを有するplasmablastic lymphoma/myelomaの1例2018

    • Author(s)
      吉原享子, 吉原哲, 松田育雄, 松尾祥平, 今戸健人, 岡田昌也, 廣田誠, 藤盛好啓
    • Organizer
      第43回日本骨髄腫学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K07142
  • [Presentation] 非寛解白血病に対するハプロミニ移植におけるWT1測定の意義:単施設解析2018

    • Author(s)
      玉置広哉、池亀和博、海田勝仁、丸山聡、眞弓あずさ、井上貴之、 寺本昌弘、吉原哲、岡田昌也、小川啓恭
    • Organizer
      第40回日本造血細胞移植学会総会
    • Data Source
      KAKENHI-PROJECT-17K07142
  • [Presentation] The efficacy of mesenchymal stem cells for the treatment of steroid-refractory acute GVHD2018

    • Author(s)
      福永 景子, 池亀 和博, 海田 勝仁, 井上 貴之, 吉原 哲, 吉原 享子, 大杉 夕子, 玉置 広哉, 岡田 昌也, 小川 啓恭, 藤盛 好啓
    • Organizer
      日本血液学会総会
    • Data Source
      KAKENHI-PROJECT-16K07185
  • [Presentation] Detailed bone marrow plasma cell phenotyping in the patients with suspected plasma cell disorders.2018

    • Author(s)
      Yoshihara Satoshi, Yoshihara Kyoko, Ikemoto Junko, Onomoto Hitomi, Sugiyama Hiroki, Ikegame Kazuhiro, Tamaki Hiroya, Okada Masaya, Osugi Yuko, Fujimori Yoshihiro
    • Organizer
      第80回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K07142
  • [Presentation] Frailty score-based treatment strategy for transplant-ineligible elderly myeloma patients2017

    • Author(s)
      吉原享子、吉原哲、池本純子、岡田昌也、山原研一、相馬俊裕、藤盛好啓
    • Organizer
      第79回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K07142
  • [Presentation] 当院におけるテムセルHS注の管理体制の構築2017

    • Author(s)
      杉山 寛貴, 原田 由紀, 大塚 真哉, 小野本 仁美, 入江 玲子, 奥田 典子, 村田 理恵, 前田 和宏, 池本 純子, 吉原 享子, 吉原 哲, 山原 研一, 相馬 俊裕, 藤盛 好啓
    • Organizer
      第65回日本輸血・細胞治療学会総会
    • Data Source
      KAKENHI-PROJECT-17K07142
  • [Presentation] Unmanipulated HLA-haploidentical(2-3 antigen-mismatched) stem cell transplantation using myeliablative or reduced-intensity preconditioning regimen2011

    • Author(s)
      Kaida K, Ikegame K, Yoshihara S, Taniguchi K, Ishii S, Kato R, Inoue T, Okada M, Tamaki H, Fujioka T, Soma T, Ogawa H.
    • Organizer
      The 53th annual meeting of the American Society of Hematology
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PROJECT-21591252
  • [Presentation] Host regulatory T cells contribute to the regulation of GVHD in murine MHC haploidentical BMT models2011

    • Author(s)
      井上貴之、池亀和博、吉原哲、海田勝仁、谷口享子、玉置広哉、藤岡龍哉、岡田昌也、加藤るり、山本庸子、相馬俊裕、小川啓恭
    • Organizer
      第73回日本血液学会学術集会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-10-14
    • Data Source
      KAKENHI-PROJECT-21591252
  • [Presentation] High risk of graft rejection in cases with HLA anitibodies undergoing haploidentical SCT without TCD2010

    • Author(s)
      吉原哲, et al.
    • Organizer
      第72回日本血液学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2010-09-25
    • Data Source
      KAKENHI-PROJECT-21591252
  • 1.  TAMAKI Hiroya (70416254)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 2.  IKEGAME Kazuhiro (20372609)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 8 results
  • 3.  OKADA Masaya (00309452)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 20 results
  • 4.  相馬 俊裕 (40273619)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 7 results
  • 5.  OGAWA Hiroyasu (80194447)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 10 results
  • 6.  FUJIOKA Tatsuya (70403045)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 7.  吉原 享子 (80595265)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 19 results
  • 8.  松田 育雄 (50335452)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  廣田 誠一 (50218856)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  藤原 弘 (20398291)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  大星 真貴子 (60648252)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  閔 庚徳 (00909004)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  砂山 勇 (40974770)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  朝倉 正紀 (80443505)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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