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KOBAYASI TETSUYA  小林 徹也

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KOBAYASHI Tetsuya  小林 徹也

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Researcher Number 90513359
Other IDs
Affiliation (Current) 2025: 東京大学, 生産技術研究所, 教授
Affiliation (based on the past Project Information) *help 2022 – 2025: 東京大学, 生産技術研究所, 教授
2023: 東京大学, 生産技術研究所, 准教授
2010 – 2021: 東京大学, 生産技術研究所, 准教授
2012: 東京大学, 生産技術研究所, 講師
2009 – 2010: 東京大学, 生産技術研究所, 講師
Review Section/Research Field
Principal Investigator
Transformative Research Areas, Section (IV) / System genome science / Basic Section 13010:Mathematical physics and fundamental theory of condensed matter physics-related / Complex systems / Basic Section 43060:System genome science-related / Constructive Systems Biology / Science and Engineering / Biological Sciences
Except Principal Investigator
Complex systems / Developmental biology / General anatomy (including histology/embryology) / General anatomy (including Histology/Embryology) / Biological Sciences
Keywords
Principal Investigator
理論生物学 / 強化学習 / 定量生物学 / T細胞 / エントロピー正則化 / 最適制御 / 非平衡熱力学 / 自己複製 / 多様性 / 低次元化 … More / バイオインフォマティクス / レパトア / NGS / T細胞受容体 / 数理モデル / 生体生命情報学 / 数理工学 / 非平衡ダイナミクス / 点過程 / GENERIC / 一般化勾配流 / 迷路探索 / 平均場制御 / 自律分散 / 自己触媒 / 情報幾何 / 完全適応 / 部分観測制御 / 確率モデリング / 受容体応答 / 最適フィルター / Fisherの基本定理 / 化学走性 / 情報幾何学 / 非平衡化学熱力学 / 分散部分観測制御 / 生物物理学 / 化学熱力学 / 学習理論 / 適応現象 / 細胞系譜 / リボソーム / 細胞分裂 / 変分構造 / ゆらぎ定理 / 深層ネットワーク / 表現型進化 / 学習ダイナミクス / クローン分布 / 自然勾配 / T細胞レパトア / 深層強化学習 / クローン選択 / 生物物理 / GUI / 整数計画法 / 再生補助医療 / 核同定 / 隠れ状態 / 分岐過程 / 発生系譜 / 着床前杯 / 生殖補助医療 / 発生 / モデル化とシミュレーション / 深層学習 / トラッキング / 系譜解析 / 力学モデル / 4Dイメージング / 着床前胚 / 免疫学 / 微分方程式モデル / シーケンス解析 / T細胞受容体レパトア / 胸腺上皮細胞 / 胸腺 / 恒常性 / 論理演算 / 分子ネットワーク / ゆらぎ / ノイズ耐性 / LDA / 1細胞 / T細胞レセプター / 次世代シーケンサー / 複雑系 / 適応免疫 / 免疫レパトア / 免疫レパートリ / バイオイメージ / 哺乳類 / 時空間動態 / 初期発生 / バイオイメージインフォマティクス / 画像解析 / バイオイメージング / シミュレーション工学 / 細胞・組織 / 発生・分化 … More
Except Principal Investigator
ライブイメージング / ゼブラフィッシュ / 発生学・形態形成学 / 細胞極性 / 情報熱力学 / 非平衡統計力学 / 生物物理学 / 情報物理学 / 非線形システム / 代謝経路 / 遺伝子回路 / 合成生物学 / 並列シュミレーション / 並列シミュレーション / 複雑ネットワーク / 確率過程 / 非線形動力学 / 人工遺伝子回路 / 発生生物学 / 卵管 / マウス / 形態形成 / イメージング / 体節形成 / ニワトリ初期胚 / 細胞遊走 / 中胚葉 / ニワトリ胚 / 数理モデル / 初期胚 / 細胞 / 発生 / 哺乳類 Less
  • Research Projects

    (22 results)
  • Research Products

    (285 results)
  • Co-Researchers

    (52 People)
  •  EPIC assembly: emergence of novel functional assembly by Evo-Physico Information CouplingArea Organizer

    • Area Organizer
      小林 徹也
    • Project Period (FY)
      2025 – 2029
    • Research Category
      Grant-in-Aid for Transformative Research Areas (A)
  •  進化情報アセンブリによる生命機能の創出原理Principal Investigator

    • Principal Investigator
      小林 徹也
    • Project Period (FY)
      2025 – 2029
    • Research Category
      Grant-in-Aid for Transformative Research Areas (A)
    • Review Section
      Transformative Research Areas, Section (IV)
    • Research Institution
      The University of Tokyo
  •  進化情報アセンブリの統合理論と進化則の解読技術の構築Principal Investigator

    • Principal Investigator
      小林 徹也
    • Project Period (FY)
      2025 – 2029
    • Research Category
      Grant-in-Aid for Transformative Research Areas (A)
    • Review Section
      Transformative Research Areas, Section (IV)
    • Research Institution
      The University of Tokyo
  •  Thermodynamics of self-replicationPrincipal Investigator

    • Principal Investigator
      小林 徹也
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 13010:Mathematical physics and fundamental theory of condensed matter physics-related
    • Research Institution
      The University of Tokyo
  •  Optimization theory for proto-intelligence and its applicationsPrincipal Investigator

    • Principal Investigator
      小林 徹也
    • Project Period (FY)
      2024 – 2025
    • Research Category
      Grant-in-Aid for Transformative Research Areas (A)
    • Review Section
      Transformative Research Areas, Section (IV)
    • Research Institution
      The University of Tokyo
  •  Computational theory for complex dynamics and its applicationsPrincipal Investigator

    • Principal Investigator
      小林 徹也
    • Project Period (FY)
      2024 – 2025
    • Research Category
      Grant-in-Aid for Transformative Research Areas (A)
    • Review Section
      Transformative Research Areas, Section (IV)
    • Research Institution
      The University of Tokyo
  •  Quantitative understanding of self-replication of cellsPrincipal Investigator

    • Principal Investigator
      KOBAYASHI TETSUYA
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 43060:System genome science-related
    • Research Institution
      The University of Tokyo
  •  Information physics of living matters

    • Principal Investigator
      岡田 康志
    • Project Period (FY)
      2019 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Complex systems
    • Research Institution
      The University of Tokyo
  •  Information Physics of Biological AdaptationsPrincipal Investigator

    • Principal Investigator
      Kobayashi Tetsuya
    • Project Period (FY)
      2019 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Complex systems
    • Research Institution
      The University of Tokyo
  •  深層ネットワークを援用した表現型制約と表現型進化原理の探索と普遍構造の探求Principal Investigator

    • Principal Investigator
      小林 徹也
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Research Institution
      The University of Tokyo
  •  低次元化に基づく免疫受容体配列ダイバーシティ解析手法の改良と応用展開Principal Investigator

    • Principal Investigator
      小林 徹也
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Research Institution
      The University of Tokyo
  •  Quantitative Immunology of T cell homeostasisPrincipal Investigator

    • Principal Investigator
      小林 徹也
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Constructive Systems Biology
    • Research Institution
      The University of Tokyo
  •  Development of informatics techniques for analysis developmental lineagesPrincipal Investigator

    • Principal Investigator
      Kobayashi Tetsuya
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (A)
    • Research Field
      System genome science
    • Research Institution
      The University of Tokyo
  •  Statistical methods for immuno-repertoire analysis based on TCR sequence dataPrincipal Investigator

    • Principal Investigator
      Kobayashi Tetsuya
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      System genome science
    • Research Institution
      The University of Tokyo
  •  確率変動にロバスト性を有する演算素子の設計理論と分子実装Principal Investigator

    • Principal Investigator
      小林 徹也
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Science and Engineering
    • Research Institution
      The University of Tokyo
  •  Mechanisms controlling the multilevel polarity formation in the mouse oviduct

    • Principal Investigator
      FUJIMORI Toshihiko
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Developmental biology
    • Research Institution
      National Institute for Basic Biology
  •  In vivo measurement of developmental signaling activities during dorso-ventral patterning in zebrafish embryo

    • Principal Investigator
      KONDOW Akiko
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General anatomy (including histology/embryology)
    • Research Institution
      Fujita Health University
  •  Design and Analysis for Dynamical Genetic Circuits based on various Mathematical Models

    • Principal Investigator
      YAMAMURA Masayuki
    • Project Period (FY)
      2011 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Complex systems
    • Research Institution
      Tokyo Institute of Technology
  •  Live imaging of mesodermal cell migration during chick gastrulation

    • Principal Investigator
      NAKAYA Yukiko
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Developmental biology
    • Research Institution
      The Institute of Physical and Chemical Research
  •  Spatiotemporal analysis of cyclic gene expression in the presomitic mesoderm using novel whole-embryo-live-imaging method

    • Principal Investigator
      KONDOW Akiko
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General anatomy (including Histology/Embryology)
    • Research Institution
      Fujita Health University
  •  Cell Community in early mammalian development

    • Principal Investigator
      FUJIMORI Toshihiko
    • Project Period (FY)
      2009 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      National Institute for Basic Biology
  •  Informatics and mathematics for In siloco reconstruction of mammalian early embryogenesisPrincipal Investigator

    • Principal Investigator
      KOBAYASHI Tetsuya
    • Project Period (FY)
      2009 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 Other

All Journal Article Presentation Book

  • [Book] 機械学習を生命科学に使う!2020

    • Author(s)
      小林 徹也、杉村 薫、舟橋 啓
    • Total Pages
      240
    • Publisher
      羊土社
    • ISBN
      9784758103916
    • Data Source
      KAKENHI-PROJECT-19H03216
  • [Book] "機械学習を生命科学に使う! : シークエンスや画像データをどう解析し、新たな生物学的発見につなげるか?"2020

    • Author(s)
      小林 徹也
    • Publisher
      羊土社
    • ISBN
      9784758103916
    • Data Source
      KAKENHI-ORGANIZER-19H05794
  • [Book] 機械学習を生命科学に使う!2020

    • Author(s)
      小林 徹也、杉村 薫、舟橋 啓
    • Total Pages
      240
    • Publisher
      羊土社
    • ISBN
      9784758103916
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Book] 定量生物学2018

    • Author(s)
      小林 徹也
    • Total Pages
      290
    • Publisher
      化学同人
    • ISBN
      9784759817300
    • Data Source
      KAKENHI-PROJECT-16H06155
  • [Journal Article] Population dynamics models for various forms of adaptation2023

    • Author(s)
      Nakashima So、J. Kobayashi Tetsuya
    • Journal Title

      Biophysics and Physicobiology

      Volume: 20 Issue: 3 Pages: n/a

    • DOI

      10.2142/biophysico.bppb-v20.0034

    • ISSN
      2189-4779
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Journal Article] Forward-Backward Sweep Method for the System of HJB-FP Equations in Memory-Limited Partially Observable Stochastic Control2023

    • Author(s)
      Tottori Takehiro、Kobayashi Tetsuya J.
    • Journal Title

      Entropy

      Volume: 25 Issue: 2 Pages: 208-208

    • DOI

      10.3390/e25020208

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22KJ0557, KAKENHI-ORGANIZER-19H05794, KAKENHI-PLANNED-19H05799
  • [Journal Article] Information geometry of dynamics on graphs and hypergraphs2023

    • Author(s)
      Kobayashi Tetsuya J.、Loutchko Dimitri、Kamimura Atsushi、Horiguchi Shuhei A.、Sughiyama Yuki
    • Journal Title

      Information Geometry

      Volume: - Issue: 1 Pages: 97-166

    • DOI

      10.1007/s41884-023-00125-w

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22KJ0632, KAKENHI-PLANNED-19H05799
  • [Journal Article] Decentralized Stochastic Control with Finite-Dimensional Memories: A Memory Limitation Approach2023

    • Author(s)
      Tottori Takehiro、Kobayashi Tetsuya J.
    • Journal Title

      Entropy

      Volume: 25 Issue: 5 Pages: 791-791

    • DOI

      10.3390/e25050791

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22KJ0557, KAKENHI-PLANNED-19H05799
  • [Journal Article] Cellular gradient flow structure linking single-cell-level rules and population-level dynamics2023

    • Author(s)
      Horiguchi Shuhei A.、Kobayashi Tetsuya J.
    • Journal Title

      Physical Review Research

      Volume: 5 Issue: 2

    • DOI

      10.1103/physrevresearch.5.l022052

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22KJ0632, KAKENHI-PLANNED-19H05799
  • [Journal Article] Characterizing the Asymmetry in Hardness between Synthesis and Destruction of Heteropolymers2022

    • Author(s)
      Kobayashi Ikumi、Sasa Shin-ichi
    • Journal Title

      Physical Review Letters

      Volume: 128 Issue: 24 Pages: 247801-247801

    • DOI

      10.1103/physrevlett.128.247801

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K20425, KAKENHI-PROJECT-23K22415, KAKENHI-ORGANIZER-19H05794, KAKENHI-PLANNED-19H05795
  • [Journal Article] Acceleration of evolutionary processes by learning and extended Fisher's fundamental theorem2022

    • Author(s)
      So Nakashima, Tetsuya J. Kobayashi
    • Journal Title

      Physical Review Research

      Volume: 4 Issue: 1 Pages: 013069-013069

    • DOI

      10.1103/physrevresearch.4.013069

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19J22607, KAKENHI-PROJECT-19H03216, KAKENHI-PLANNED-19H05799
  • [Journal Article] Kinetic derivation of the Hessian geometric structure in chemical reaction networks2022

    • Author(s)
      Kobayashi Tetsuya J.、Loutchko Dimitri、Kamimura Atsushi、Sughiyama Yuki
    • Journal Title

      Physical Review Research

      Volume: 4 Issue: 3 Pages: 033066-033066

    • DOI

      10.1103/physrevresearch.4.033066

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K21308, KAKENHI-ORGANIZER-19H05794, KAKENHI-PLANNED-19H05799
  • [Journal Article] Riemannian geometry of optimal driving and thermodynamic length and its application to chemical reaction networks2022

    • Author(s)
      Loutchko Dimitri、Sughiyama Yuki、Kobayashi Tetsuya J.
    • Journal Title

      Physical Review Research

      Volume: 4 Issue: 4 Pages: 043049-043049

    • DOI

      10.1103/physrevresearch.4.043049

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-19H05794, KAKENHI-PLANNED-19H05799
  • [Journal Article] Hessian geometric structure of chemical thermodynamic systems with stoichiometric constraints2022

    • Author(s)
      Sughiyama Yuki、Loutchko Dimitri、Kamimura Atsushi、Kobayashi Tetsuya J.
    • Journal Title

      Physical Review Research

      Volume: 4 Issue: 3 Pages: 033065-033065

    • DOI

      10.1103/physrevresearch.4.033065

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K21308, KAKENHI-ORGANIZER-19H05794, KAKENHI-PLANNED-19H05799
  • [Journal Article] Machine Learning Approaches to TCR Repertoire Analysis2022

    • Author(s)
      Katayama Yotaro、Yokota Ryo、Akiyama Taishin、Kobayashi Tetsuya J.
    • Journal Title

      Frontiers in Immunology

      Volume: 13 Pages: 858057-858057

    • DOI

      10.3389/fimmu.2022.858057

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K19391, KAKENHI-PROJECT-19K20408, KAKENHI-ORGANIZER-19H05794, KAKENHI-PLANNED-19H05799, KAKENHI-PROJECT-20H03441
  • [Journal Article] Optimal sensing and control of run-and-tumble chemotaxis2022

    • Author(s)
      Nakamura Kento、Kobayashi Tetsuya J.
    • Journal Title

      Physical Review Research

      Volume: 4 Issue: 1 Pages: 013120-013120

    • DOI

      10.1103/physrevresearch.4.013120

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20J21362, KAKENHI-PLANNED-19H05799
  • [Journal Article] Comparative Study of Repertoire Classification Methods Reveals Data Efficiency of k-mer Feature Extraction2022

    • Author(s)
      Katayama Yotaro、Kobayashi Tetsuya J.
    • Journal Title

      Frontiers in Immunology

      Volume: 13

    • DOI

      10.3389/fimmu.2022.797640

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-19H05794, KAKENHI-PLANNED-19H05799
  • [Journal Article] The Onsager-Machlup Integral for Non-Reciprocal Systems with Odd Elasticity2022

    • Author(s)
      Yasuda Kento、Kobayashi Akira、Lin Li-Shing、Hosaka Yuto、Sou Isamu、Komura Shigeyuki
    • Journal Title

      Journal of the Physical Society of Japan

      Volume: 91 Issue: 1 Pages: 015001-015001

    • DOI

      10.7566/jpsj.91.015001

    • NAID

      210000159508

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-20H05538, KAKENHI-PROJECT-19J20271, KAKENHI-PROJECT-22KJ1640, KAKENHI-ORGANIZER-19H05794
  • [Journal Article] Chemical thermodynamics for growing systems2022

    • Author(s)
      Sughiyama Yuki、Kamimura Atsushi、Loutchko Dimitri、Kobayashi Tetsuya J.
    • Journal Title

      Physical Review Research

      Volume: 4 Issue: 3 Pages: 033191-033191

    • DOI

      10.1103/physrevresearch.4.033191

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K21308, KAKENHI-ORGANIZER-19H05794, KAKENHI-PLANNED-19H05799
  • [Journal Article] Hessian geometry of nonequilibrium chemical reaction networks and entropy production decompositions2022

    • Author(s)
      Kobayashi Tetsuya J.、Loutchko Dimitri、Kamimura Atsushi、Sughiyama Yuki
    • Journal Title

      Physical Review Research

      Volume: 4 Issue: 3 Pages: 033208-033208

    • DOI

      10.1103/physrevresearch.4.033208

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K21308, KAKENHI-ORGANIZER-19H05794, KAKENHI-PLANNED-19H05799
  • [Journal Article] An explainable deep learning-based algorithm with an attention mechanism for predicting the live birth potential of mouse embryos2022

    • Author(s)
      Tokuoka Yuta、Yamada Takahiro G.、Mashiko Daisuke、Ikeda Zenki、Kobayashi Tetsuya J.、Yamagata Kazuo、Funahashi Akira
    • Journal Title

      Artificial Intelligence in Medicine

      Volume: 134 Pages: 102432-102432

    • DOI

      10.1016/j.artmed.2022.102432

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22KJ3051, KAKENHI-PLANNED-18H05528, KAKENHI-ORGANIZER-19H05794, KAKENHI-PLANNED-19H05799
  • [Journal Article] Memory-Limited Partially Observable Stochastic Control and Its Mean-Field Control Approach2022

    • Author(s)
      Tottori Takehiro、Kobayashi Tetsuya J.
    • Journal Title

      Entropy

      Volume: 24 Issue: 11 Pages: 1599-1599

    • DOI

      10.3390/e24111599

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22KJ0557, KAKENHI-ORGANIZER-19H05794, KAKENHI-PLANNED-19H05799
  • [Journal Article] Asynchronous division at 4-8-cell stage of preimplantation embryos affects live birth through ICM/TE differentiation2022

    • Author(s)
      Mashiko Daisuke、Ikeda Zenki、Tokoro Mikiko、Hatano Yu、Yao Tatsuma、Kobayashi Tetsuya J.、Fukunaga Noritaka、Asada Yoshimasa、Yamagata Kazuo
    • Journal Title

      Scientific Reports

      Volume: 12 Issue: 1 Pages: 9411-9411

    • DOI

      10.1038/s41598-022-13646-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22KJ3051, KAKENHI-PLANNED-18H05528, KAKENHI-ORGANIZER-19H05794, KAKENHI-PLANNED-19H05799
  • [Journal Article] Representation and inference of size control laws by neural-network-aided point processes2021

    • Author(s)
      Kamimura Atsushi、Kobayashi Tetsuya J.
    • Journal Title

      Physical Review Research

      Volume: 3 Issue: 3

    • DOI

      10.1103/physrevresearch.3.033032

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03216, KAKENHI-PLANNED-19H05799
  • [Journal Article] Forward and Backward Bellman Equations Improve the Efficiency of the EM Algorithm for DEC-POMDP2021

    • Author(s)
      Tottori Takehiro、Kobayashi Tetsuya J.
    • Journal Title

      Entropy

      Volume: 23 Issue: 5 Pages: 551-551

    • DOI

      10.3390/e23050551

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22KJ0557, KAKENHI-PLANNED-19H05799
  • [Journal Article] 大腸菌走化性における感知・応答の情報論的な最適性2021

    • Author(s)
      中村絢斗、小林徹也
    • Journal Title

      生体の科学

      Volume: 3 Pages: 239-244

    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Journal Article] Connection between the Bacterial Chemotactic Network and Optimal Filtering2021

    • Author(s)
      Kento Nakamura, Tetsuya J. Kobayashi
    • Journal Title

      Physical Review Letters

      Volume: 126 Issue: 12 Pages: 128102-128102

    • DOI

      10.1103/physrevlett.126.128102

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20J21362, KAKENHI-ORGANIZER-19H05794, KAKENHI-PLANNED-19H05799
  • [Journal Article] Understanding adaptive immune system as reinforcement learning2021

    • Author(s)
      Kato Takuya、Kobayashi Tetsuya J.
    • Journal Title

      Physical Review Research

      Volume: 3 Issue: 1 Pages: 013222-013222

    • DOI

      10.1103/physrevresearch.3.013222

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Journal Article] 3D convolutional neural networks-based segmentation to acquire quantitative criteria of the nucleus during mouse embryogenesis2020

    • Author(s)
      Tokuoka Yuta、Yamada Takahiro G.、Mashiko Daisuke、Ikeda Zenki、Hiroi Noriko F.、Kobayashi Tetsuya J.、Yamagata Kazuo、Funahashi Akira
    • Journal Title

      npj Systems Biology and Applications

      Volume: 6 Issue: 1 Pages: 32-32

    • DOI

      10.1038/s41540-020-00152-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-18H05528, KAKENHI-PROJECT-18H02357, KAKENHI-PROJECT-19H03216, KAKENHI-PROJECT-19J13189, KAKENHI-ORGANIZER-19H05794, KAKENHI-PLANNED-19H05799
  • [Journal Article] Lineage EM algorithm for inferring latent states from cellular lineage trees2020

    • Author(s)
      Nakashima So、Sughiyama Yuki、Kobayashi Tetsuya J
    • Journal Title

      Bioinformatics

      Volume: 36 Issue: 9 Pages: 2829-2838

    • DOI

      10.1093/bioinformatics/btaa040

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K17763, KAKENHI-PROJECT-19H03216, KAKENHI-ORGANIZER-19H05794, KAKENHI-PLANNED-19H05799
  • [Journal Article] Reliable target ligand detection by noise-induced receptor cluster formation2020

    • Author(s)
      Kajita Masashi K.、Aihara Kazuyuki、Kobayashi Tetsuya J.
    • Journal Title

      Chaos: An Interdisciplinary Journal of Nonlinear Science

      Volume: 30 Issue: 1 Pages: 011104-011104

    • DOI

      10.1063/1.5140714

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K18147, KAKENHI-PUBLICLY-18H05096, KAKENHI-ORGANIZER-19H05794, KAKENHI-PLANNED-19H05799, KAKENHI-PROJECT-15H05707
  • [Journal Article] 生命科学における機械学習の応用とその課題2020

    • Author(s)
      小林 徹也
    • Journal Title

      数理科学

      Volume: 58 Pages: 43-49

    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Journal Article] Bayesian gates for reliable logical operations under noisy conditions2020

    • Author(s)
      Kobayashi Tetsuya J
    • Journal Title

      PHYSICAL REVIEW E

      Volume: 101 Issue: 4 Pages: 042205-042205

    • DOI

      10.1103/physreve.101.042205

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-19H05794, KAKENHI-PLANNED-19H05799
  • [Journal Article] Fitness Gain of Individually Sensed Information by Cells2019

    • Author(s)
      Kobayashi Tetsuya J.、Sughiyama Yuki
    • Journal Title

      Entropy

      Volume: 21 Issue: 10 Pages: 1002-1002

    • DOI

      10.3390/e21101002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H03216, KAKENHI-PROJECT-16K17763, KAKENHI-ORGANIZER-19H05794, KAKENHI-PLANNED-19H05799
  • [Journal Article] Quantitative analysis reveals reciprocal regulations underlying recovery dynamics of thymocytes and thymic environment in mice2019

    • Author(s)
      Kaneko Kazumasa B.、Tateishi Ryosuke、Miyao Takahisa、Takakura Yuki、Akiyama Nobuko、Yokota Ryo、Akiyama Taishin、Kobayashi Tetsuya J.
    • Journal Title

      Communications Biology

      Volume: 2 Issue: 1 Pages: 444-444

    • DOI

      10.1038/s42003-019-0688-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08622, KAKENHI-PUBLICLY-18H05096, KAKENHI-PUBLICLY-18H04989, KAKENHI-ORGANIZER-19H05794, KAKENHI-PLANNED-19H05799, KAKENHI-PROJECT-17H04038
  • [Journal Article] Quantitative Analysis Reveals Reciprocal Regulations Underlying Recovery Dynamics of Thymocytes and Thymic Environment in Mice2019

    • Author(s)
      Kazumasa B Kaneko, Ryosuke Tateishi, Takahisa Miyao, Yuki Takakura, Nobuko Akiyama, Ryo Yokota , Taishin Akiyama, Tetsuya J. Kobayashi
    • Journal Title

      Communications Biology

      Volume: 印刷中

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17KT0014
  • [Journal Article] Long-term hindlimb unloading causes a preferential reduction of medullary thymic epithelial cells expressing autoimmune regulator (Aire)2018

    • Author(s)
      Horie Kenta、Kudo Takashi、Yoshinaga Riko、Akiyama Nobuko、Sasanuma Hiroki、Kobayashi Tetsuya J.、Shimbo Miki、Jeon Hyojung、Miyao Takahisa、Miyauchi Maki、Shirakawa Masaki、Shiba Dai、Yoshida Nobuaki、Muratani Masafumi、Takahashi Satoru、Akiyama Taishin
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 501 Issue: 3 Pages: 745-750

    • DOI

      10.1016/j.bbrc.2018.05.060

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08622, KAKENHI-PUBLICLY-18H04965, KAKENHI-PUBLICLY-18H04989, KAKENHI-PUBLICLY-18H05096, KAKENHI-PROJECT-17H04038, KAKENHI-ORGANIZER-15H05935
  • [Journal Article] The explicit form of the rate function for semi-Markov processes and its contractions2018

    • Author(s)
      Yuki Sughiyama, Testuya J. Kobayashi
    • Journal Title

      Journal of Physics A: Mathematical and Theoretical

      Volume: 51 Issue: 12 Pages: 125001-125001

    • DOI

      10.1088/1751-8121/aaab6d

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K17763, KAKENHI-PROJECT-16H06155
  • [Journal Article] Stochastic and information-thermodynamic structures of population dynamics in a fluctuating environment2017

    • Author(s)
      Testuya J. Kobayashi, Yuki Sughiyama
    • Journal Title

      Physical Review E

      Volume: 96 Issue: 1 Pages: 012402-012402

    • DOI

      10.1103/physreve.96.012402

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K17763, KAKENHI-PROJECT-16H06155
  • [Journal Article] Quantification of Inter-Sample Differences in T-Cell Receptor Repertoires Using Sequence-Based Information2017

    • Author(s)
      Yokota Ryo、Kaminaga Yuki、Kobayashi Tetsuya J.
    • Journal Title

      Frontiers in Immunology

      Volume: 8 Pages: 1500-1500

    • DOI

      10.3389/fimmu.2017.01500

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17KT0014
  • [Journal Article] システム生物学と免疫系の自己-非自己識別2016

    • Author(s)
      秋山泰身, 小林徹也
    • Journal Title

      医学の歩み

      Volume: 259 Pages: 839-842

    • Data Source
      KAKENHI-PROJECT-15K14433
  • [Journal Article] Discreteness-induced transitions in multibody reaction systems2016

    • Author(s)
      Yohei Saito, Yuki Sughiyama, Kunihiko Kaneko, Tetsuya J. Kobayashi
    • Journal Title

      Physical Review E

      Volume: 94 Issue: 2 Pages: 22140-22140

    • DOI

      10.1103/physreve.94.022140

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PUBLICLY-15H00800
  • [Journal Article] Positive and negative regulatory mechanisms for fine-tuning cellularity and functions of medullary thymic epithelial cells2015

    • Author(s)
      Taishin Akiyama, Ryosuke Tateishi, Nobuko Akiyama, Riko Yoshinaga, Tetsuya J. Kobayashi
    • Journal Title

      Frontier Immunology

      Volume: 6 Pages: 1-6

    • DOI

      10.3389/fimmu.2015.00461

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K14433, KAKENHI-PUBLICLY-15H01150, KAKENHI-PROJECT-26670234
  • [Journal Article] Improved and robust detection of cell nuclei from four dimensional fluorescence images.2014

    • Author(s)
      Bashar MK, Yamagata K, Kobayashi TJ.
    • Journal Title

      PLoS One

      Volume: 9 Issue: 7 Pages: e101891-e101891

    • DOI

      10.1371/journal.pone.0101891

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-21116001, KAKENHI-PLANNED-25116005, KAKENHI-PUBLICLY-25125712, KAKENHI-PROJECT-25712035, KAKENHI-PROJECT-26660250
  • [Journal Article] 細胞のふるまいを読み解く時系列に潜む情報量2013

    • Author(s)
      小林徹也、上村淳
    • Journal Title

      実験医学

      Volume: Vol.31(8) Pages: 1239-1244

    • Data Source
      KAKENHI-PLANNED-21116006
  • [Journal Article] Single Cell Visualization of Yeast Gene Expression Shows Correlation of Epigenetic Switching Between Multiple Heterochromatic Regions Through Multiple Generations2013

    • Author(s)
      Y.Mano, T.J. Kobayashi, J.Nakayama, H.Uchida, M.Oki
    • Journal Title

      Plos Biology

      Volume: Vol.11

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21116006
  • [Journal Article] 定量データが切り開く生命科学2013

    • Author(s)
      小林徹也
    • Journal Title

      実験医学

      Volume: 31 Pages: 1202-1208

    • Data Source
      KAKENHI-PLANNED-23119008
  • [Journal Article] Single Cell Visualization of Yeast Gene Expression Shows Correlation of Epigenetic Switching Between Multiple Heterochromatic Regions Through Multiple Generations2013

    • Author(s)
      Yasunobu Mano, Tetsuya J. Kobayashi, Jun-ichi Nakayama, Hiroyuki Uchida, Masaya Oki
    • Journal Title

      Plos Biology

      Volume: 11 Issue: 7 Pages: e1001601-e1001601

    • DOI

      10.1371/journal.pbio.1001601

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21116006, KAKENHI-ORGANIZER-23114001, KAKENHI-PLANNED-23114005, KAKENHI-PLANNED-23119008, KAKENHI-PROJECT-23370004
  • [Journal Article] 定量データが切り開く生命科学2013

    • Author(s)
      小林徹也
    • Journal Title

      実験医学

      Volume: Vol.31(8) Pages: 1202-1208

    • Data Source
      KAKENHI-PLANNED-21116006
  • [Journal Article] Automatic Extraction of Nuclei Centroids of Mouse Embronic Cells from Fluorescence Microscopy Images2012

    • Author(s)
      K.Bashar, K.Komatsu, T.Fujimori, T.J. Kobayashi
    • Journal Title

      Plos One

      Volume: Vol.7(5)

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21116006
  • [Journal Article] Automatic Extraction of Nuclei Centroids of Mouse Embry- onic Cells from Fluorescence Microscopy Images2012

    • Author(s)
      Md. Khayrul Bashar, Koji Komatsu, Toshihiko Fujimori and Tetsuya J. Kobayashi
    • Journal Title

      Plos One

      Volume: 7 Issue: 5 Pages: e35550-e35550

    • DOI

      10.1371/journal.pone.0035550

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21116006, KAKENHI-PLANNED-21116005
  • [Journal Article] Information processing and integration with intracellular kinetics near critical point2012

    • Author(s)
      A.Kamimura,T.J. Kobayashi
    • Journal Title

      Frontiers in Physiology

      Volume: Vol.3 Pages: 203-203

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21116006
  • [Journal Article] Theoretical aspect of cellular decision- making and information processing2012

    • Author(s)
      Kobayashi TJ, Kamimura, A
    • Journal Title

      Adv Exp Med Biol.

      Volume: 736 Pages: 275-91

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22570210
  • [Journal Article] Information Processing and integration with intracellular dynamics near critical point2012

    • Author(s)
      A. Kamimura, T. J. Kobayashi
    • Journal Title

      Frontiers in Fractal Physiology

      Volume: 3 Pages: 203-203

    • DOI

      10.3389/fphys.2012.00203

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J08104, KAKENHI-PLANNED-21116006
  • [Journal Article] Physiological intracellular crowdedness is defined by perimeter to area ratio of subcellular compartments2012

    • Author(s)
      N.Hiroi, T.Okuhara, T.Kubojima, K.Iba, A.Tabira, S.Yamashita, Y.Okada, T.J. Kobayashi,A. Funahashi
    • Journal Title

      Frontiers in Physiology

      Volume: Vol.3 Pages: 293-293

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21116006
  • [Journal Article] Physiological intracellular crowdedness is defined by perimeter to area ratio of subcellular compartments2012

    • Author(s)
      Noriko Hiroi, Takahiro Okuhara, Takeshi Kubojima, Keisuke Iba, Akito Tabira, Shuji Yamashita, Yasunori Okada, Tetsuya J. Kobayashi, Akira Funahashi
    • Journal Title

      Frontiers in Physiology

      Volume: 7 Pages: 293-293

    • DOI

      10.3389/fphys.2012.00293

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21116006
  • [Journal Article] Theoretical aspect of cellular decision-making and information processing2012

    • Author(s)
      Tetsuya J. Kobayashi
    • Journal Title

      Advances in Experimental Medicine and Biology

      Volume: vol. 736 Pages: 275-291

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23119008
  • [Journal Article] Dynamics of intracellular information decoding2011

    • Author(s)
      Kobayashi TJ, Kamimura A
    • Journal Title

      Phys Biol.

      Volume: 8 Pages: 55007-55007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22570210
  • [Journal Article] Perturbation analyses of intermolecular interactions2011

    • Author(s)
      Koyama YM, Kobayashi TJ, Tomoda S, Hiroki R
    • Journal Title

      Physical Review

      Volume: E84 Pages: 46702-46702

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22570210
  • [Journal Article] Connection between noise- induced symmetry breaking and an information -decoding function for intracellular networks2011

    • Author(s)
      Kobayashi TJ
    • Journal Title

      Physical Review Letters

      Volume: 106 Pages: 228101-228101

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22570210
  • [Journal Article] Perturbation analyses of intermolecular interactions2011

    • Author(s)
      Yohei M.Koyama, Tetsuya J.Kobayashi, Hiroki R.Ueda
    • Journal Title

      Physical Review E

      Volume: 84 Pages: 26704-26704

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21116006
  • [Journal Article] Perturbation analyses of intermolecular interactions2011

    • Author(s)
      Y. M. Koyama, T.J. Kobayashi, H.R. Ueda
    • Journal Title

      Physical Review E

      Volume: Vol.84 Pages: 26704-26704

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21116006
  • [Journal Article] Dynamics of Intracellular Information decoding2011

    • Author(s)
      Kobayashi TJ, Atsushi Kamimura A
    • Journal Title

      Physical Biology

      Volume: 8 Pages: 55007-55007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22570210
  • [Journal Article] Atypical Cadherins Dachsous and Fat Control Dynamics of Noncentrosomal Microtubules in Planar Cell Polarity2010

    • Author(s)
      Toshiyuki Harumoto, Masayoshi Ito, Yuko Shimada, Tetsuya J.Kobayashi, Hiroki R.Ueda, Bingwei Lu
    • Journal Title

      Developmental cell

      Volume: 19 Pages: 389-401

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21116006
  • [Journal Article] Atypical Cadherins Dachsous and Fat Control Dynamics of Noncentrosomal Microtubules in Planar Cell Polarity2010

    • Author(s)
      T.Harumoto, M.Ito, Y.Shimada,T.J. Kobayashi, H.R. Ueda, B.Lu, T.Uemura
    • Journal Title

      Developmental cell

      Volume: Vol.19 Pages: 389-401

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21116006
  • [Journal Article] Atypical Cadherins Dachsous and Fat Control Dynamics of Noncentrosomal Microtubules in Planar Cell Polarity2010

    • Author(s)
      Harumoto T, Ito M, Shimada Y, Kobayashi TJ, Ueda HR, Lu B, and Uemura T
    • Journal Title

      Developmental cell

      Volume: 19 Pages: 389-401

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22570210
  • [Journal Article] Implementation of Dynamic Bayesian Decision Making by Intracellular Kinetics2010

    • Author(s)
      Kobayashi TJ
    • Journal Title

      Physical Review Letters

      Volume: 104 Pages: 228104-228104

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22570210
  • [Presentation] ストレス条件下における髄質胸腺上皮細胞の分化ダイナミクス変化の情報学的解析2024

    • Author(s)
      木下 恭兵, 小林 徹也
    • Organizer
      第8回理論免疫学ワークショップ
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] 計算資源制限を伴う最適推定制御とその生体情報処理への応用:記憶の相転移2024

    • Author(s)
      鳥取 岳広, 小林 徹也
    • Organizer
      定量生物学の会 第十一回年会
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] 細胞増殖を統合した分化軌道推定手法の開発と胸腺細胞のロバスト性解明への応用2024

    • Author(s)
      木下 恭兵, 小林 徹也
    • Organizer
      定量生物学の会 第十一回年会
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] epiNMF: a Novel Method to Uncover the Influence of Epigenome on Local Mutation Rates2024

    • Author(s)
      Machiko Katori, Hiroyuki Yamasaki, Tetsuya Yamada-Saito, Tetsuya J. Kobayashi, Shoi Shi
    • Organizer
      Gordon Research Seminar, DNA Damage, Mutation and Cancer
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] 細胞集団の勾配流によるモデリング2024

    • Author(s)
      堀口 修平, 小林 徹也
    • Organizer
      第8回理論免疫学ワークショップ
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] 環境を通じて情報共有する細胞集団の強化学習的理解2024

    • Author(s)
      加藤雅己, 小林徹也
    • Organizer
      第8回理論免疫学ワークショップ
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] 歴史から紐解く化学反応論と化学熱力学2024

    • Author(s)
      小林 徹也
    • Organizer
      定量生物学の会 第十一回年会
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] 一般化勾配流による多細胞システムのモデル化2024

    • Author(s)
      堀口 修平, 小林 徹也
    • Organizer
      定量生物学の会 第十一回年会
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] ジャンプ過程に対する線形可解な確率最適制御2023

    • Author(s)
      堀口 修平, 小林 徹也
    • Organizer
      2023年度数理生物学会年会
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] 化学反応システムの熱力学とその応用2023

    • Author(s)
      小林徹也
    • Organizer
      定量生物学の会 第十回年会
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] Chemical thermodynamics for growing compartments with stoichiometric constraints2023

    • Author(s)
      Atsushi Kamimura, Yuki Sughiyama, Tetsuya J. Kobayashi
    • Organizer
      日本生物物理学会第61回年次大会
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] 観測と記憶が制限された確率最適制御問題の解法:確率空間上のポントリャーギンの最小原理と前向き後向きスイープ法2023

    • Author(s)
      鳥取岳広, 小林徹也
    • Organizer
      計測自動制御学会第10回制御部門マルチシンポジウム
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] 深層学習によるTCR-pMHC結合予測2023

    • Author(s)
      堅山 耀太郎, 小林 徹也
    • Organizer
      第7回理論免疫学ワークショップ
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] Noise-induced receptor clustering as a functional role of noise for reducing errors in target ligand detection2023

    • Author(s)
      Masashi K. Kajita, Kazuyuki Aihara, Tetsuya J. Kobayashi
    • Organizer
      28th International Conference on Statistical Physics
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] Uncovering the Influence of Epigenetics on Local Mutation Rates through a Comprehensive Analysis of Epigenomic and Genomic Data2023

    • Author(s)
      Machiko Katori, Tetsuya Yamada, Tetsuya J. Kobayashi, Shoi Shi
    • Organizer
      Probabilistic Modeling in Genomics 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] Using and Creating Control Theory for Biological Problems2023

    • Author(s)
      Tetsuya J. Kobayashi
    • Organizer
      10th International Congress on Industrial and Applied Mathematics
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] Limits of gradient sensing with a dynamically changing cell shape2023

    • Author(s)
      Kento Nakamura, Tetsuya J. Kobayashi
    • Organizer
      28th International Conference on Statistical Physics
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] Cellular gradient flow structure connects single-cell-level rules and population-level dynamics2023

    • Author(s)
      Shuhei A. Horiguchi, Tetsuya J. Kobayashi
    • Organizer
      STATPHY, Satellite Meeting, Statistical Physics, Information-Processing in Living Systems
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] The Hessian Geometry of Thermodynamic Uncertainty Relations in Chemical Reaction Networks2023

    • Author(s)
      Dimitri Loutchko, Atsushi Kamimura, Yuki Sughiyama, Tetsuya J. Kobayashi
    • Organizer
      28th International Conference on Statistical Physics
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] 胸腺上皮細胞のシングルセル解析2023

    • Author(s)
      木下 恭兵, 小林 徹也
    • Organizer
      第7回理論免疫学ワークショップ
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] グラフニューラルネットワークによる分子表現と匂い認知の予測への応用2023

    • Author(s)
      小林徹也
    • Organizer
      第7回理論免疫学ワークショップ
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] 体積成長を考慮した自己複製系の化学熱力学2023

    • Author(s)
      上村淳, 杉山友規, 小林徹也
    • Organizer
      「細胞を創る」研究会16.0
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] 機械学習ベースの隠れ状態推定手法の比較と生物データへの応用2023

    • Author(s)
      谷本 佑馬, 上村 淳, 小林 徹也
    • Organizer
      第26回情報論的学習理論ワークショップ
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] Information Geometry of Equilibrium and Nonequilibrium Chemical Reaction Networks2023

    • Author(s)
      Tetsuya J. Kobayashi, Dimitri Loutchko, Atsushi Kamimura, Yuki Sughiyama
    • Organizer
      28th International Conference on Statistical Physics
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] Optimality of Biological Information Processing2023

    • Author(s)
      Tetsuya J. Kobayashi
    • Organizer
      Biomedical Mathematics Online Colloquium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] ゆらいだ生体時系列データから隠れた変動を見出す機械・深層学習手法2023

    • Author(s)
      小林 徹也
    • Organizer
      第96回日本生化学会大会
    • Invited
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] Optimal Information Processing and Control in Living Systems with limited resources2023

    • Author(s)
      Tetsuya J. Kobayashi
    • Organizer
      STATPHYS28 Satellite Meeting:Statistical Physics and Information-Processing in Living Systems
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] Hessian geometric derivation of macroscopic thermodynamic uncertainty relations (TUR)2023

    • Author(s)
      Dimitri Loutchko, Tetsuya J. Kobayashi
    • Organizer
      10th International Congress on Industrial and Applied Mathematics
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] 細胞を創るための平衡・非平衡化学熱力学2023

    • Author(s)
      小林 徹也, 杉山友規, Dimitri Loutchko, 上村 淳
    • Organizer
      「細胞を創る」研究会16.0
    • Invited
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] 生物学的制約を考慮した最適推定制御問題における記憶の相転移2023

    • Author(s)
      鳥取 岳広, 小林 徹也
    • Organizer
      日本物理学会2023年秋季大会
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] Chemical thermodynamics for growing protocells2023

    • Author(s)
      Atsushi Kamimura, Yuki Sughiyama, Tetsuya J. Kobayashi
    • Organizer
      Origins of Life Donostia Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] Generalized gradient flow modeling of the cellular population dynamics and a T-cell immune response model2023

    • Author(s)
      Shuhei A. Horiguchi, Tetsuya J. Kobayashi
    • Organizer
      The 8th CIJK Conference on Mathematical and Theoretical Biology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] 伸長方向を制御する細胞による勾配方向の推定限界2023

    • Author(s)
      中村絢斗, 小林徹也
    • Organizer
      2023年度数理生物学会年会
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] 環境を通じて情報共有する細胞集団の強化学習的理解2023

    • Author(s)
      加藤雅己, 小林徹也
    • Organizer
      2023年度数理生物学会年会
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] ハイパーグラフ上の非線形一般化勾配流とその情報幾何学構造2023

    • Author(s)
      小林 徹也
    • Organizer
      第26回情報論的学習理論ワークショップ
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] Chemical thermodynamics for growing compartments2023

    • Author(s)
      Atsushi Kamimura, Yuki Sughiyama, Tetsuya J. Kobayashi
    • Organizer
      Molecular Origins of Life
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] The fate of growing systems under themorynamic and stoichiometric constraints2023

    • Author(s)
      Atsushi Kamimura, Yuki Sughiyama, Tetsuya J. Kobayashi
    • Organizer
      28th International Conference on Statistical Physics
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] Cellular gradient flow structure connects single-cell-level rules and population-level dynamics2023

    • Author(s)
      Shuhei A. Horiguchi, Tetsuya J. Kobayashi
    • Organizer
      10th International Congress on Industrial and Applied Mathematics
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] リソース制約部分観測最適制御理論:生体情報処理の理解にむけた自由エネルギー原理とは違うルート2023

    • Author(s)
      小林 徹也
    • Organizer
      「あいまい脳」 班会議
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-19H05794
  • [Presentation] Partially Observable Stochastic Control with Memory Limitation and Mean-Field Approach2023

    • Author(s)
      Takehiro Tottori, Tetsuya J. Kobayashi
    • Organizer
      10th International Congress on Industrial and Applied Mathematics
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] 分散型確率最適制御問題に対する記憶制限アプローチ2023

    • Author(s)
      鳥取 岳広, 小林 徹也
    • Organizer
      第67回システム制御情報学会研究発表講演会
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] グラフNNによる化学分子表現学習とその匂い認知予測への応用2023

    • Author(s)
      小林 徹也, 梦吉, 舟橋 啓
    • Organizer
      日本生物物理学会第61回年次大会
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] Spectral Graph NNによる化学分子表現とその匂い認知予測への応用2023

    • Author(s)
      小林徹也
    • Organizer
      2023年度数理生物学会年会
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] リソース制約部分観測最適制御理論:生体情報処理の理解にむけた自由エネルギー原理とは違うルート2023

    • Author(s)
      小林徹也
    • Organizer
      「あいまい脳」 班会議
    • Invited
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] Cellular gradient flow structure connects single-cell-level rules and population-level dynamics2023

    • Author(s)
      Shuhei A. Horiguchi, Tetsuya J. Kobayashi
    • Organizer
      28th International Conference on Statistical Physics
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] 細胞集団動態の勾配流によるモデリング2023

    • Author(s)
      堀口修平, 小林徹也
    • Organizer
      第7回理論免疫学ワークショップ
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] Optimal information processing and motor control of run-and-tumble chemotaxis under stochastic fluctuation2022

    • Author(s)
      Kento Nakamura, Tetsuya J. Kobayashi
    • Organizer
      12th European Conference on Mathematical and Theoretical Biology (ECMTB)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] Evolution of Thymic Involution Through the Lens of Learning Theory2022

    • Author(s)
      堀口修平, 小林徹也
    • Organizer
      第51回日本免疫学会学術集会
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] Riemannian Geometry of Chemical Reaction Networks and its Applications to Optimal Driving and Sensitivity2022

    • Author(s)
      Dimitri Loutchko, Tetsuya J. Kobayashi
    • Organizer
      Workshop on Non-equilibrium Phenomena in Physics and Biology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] Chemical thermodynamics for growing systems2022

    • Author(s)
      杉山友規, 上村敦・LoutchkoDimitri, 小林徹也
    • Organizer
      RIMS共同研究集会「ランダム力学系・非自励力学系研究の展望:理論と応用」
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] Cell competition in a hybrid mechanochemical model2022

    • Author(s)
      小林 徹也
    • Organizer
      25th Anniversary Symposium of German-Japanese Joint Research Project on Nonequilibrium Statistical Physics Perspectives for Future Collaboration
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-19H05794
  • [Presentation] T細胞系の定量生物学:発生からレパトアまで2022

    • Author(s)
      小林徹也
    • Organizer
      第2回ASHBi 数理ヒト生物学研究会 (MathHuB研究会)
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] Information Geometry of Equilibrium and Nonequilibrium Chemical Reaction Networks2022

    • Author(s)
      Tetsuya J. Kobayashi
    • Organizer
      Workshop on Non-equilibrium Phenomena in Physics and Biology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] 記憶が制限された部分観測確率制御2022

    • Author(s)
      鳥取岳広, 小林徹也
    • Organizer
      日本物理学会2022年秋季大会
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] "ラマン―オミクス対応が明らかにする細胞構成要素連動性の重要性 (英語タイトル:Raman-omics correspondence reveals stoichiometric balance constrains on omics changes)"2022

    • Author(s)
      亀井健一郎、小林鉱石、野添嵩、中岡秀憲、若本祐一
    • Organizer
      第45回日本分子生物学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03216
  • [Presentation] 記憶が制限された部分観測確率制御に対する平均場制御アプローチ2022

    • Author(s)
      鳥取岳広, 小林徹也
    • Organizer
      第65回自動制御連合講演会
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] T細胞系の定量生物学:発生からレパトアまで2022

    • Author(s)
      小林 徹也
    • Organizer
      第2回ASHBi 数理ヒト生物学研究会 (MathHuB研究会)
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-19H05794
  • [Presentation] A general approach to chemical thermodynamics and constraints for growing systems2022

    • Author(s)
      杉山友規, 上村淳, Dimitri Loutchko, 小林徹也
    • Organizer
      日本生物物理学会第60回年次大会
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] Gradient flow of the heterogeneous cellular population and a T-cell immune response model.2022

    • Author(s)
      Shuhei A. Horiguchi, Tetsuya J. Kobayashi
    • Organizer
      12th European Conference on Mathematical and Theoretical Biology (ECMTB)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] 細胞集団動態と1細胞動態の一般化勾配流によるモデリング2022

    • Author(s)
      堀口修平, 小林徹也
    • Organizer
      ソフトバイオ研究会2022
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] Information Geometry of Equilibrium and Nonequilibrium Chemical Reaction Networks2022

    • Author(s)
      小林 徹也
    • Organizer
      Workshop on Non-equilibrium Phenomena in Physics and Biology
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-19H05794
  • [Presentation] Hessian Geometric Structure of Equilibrium and Nonequilibrium Chemical Reaction Newtworks2022

    • Author(s)
      小林 徹也
    • Organizer
      理研 iTEMSセミナー
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-19H05794
  • [Presentation] Hessian Geometric Structure of Equilibrium and Nonequilibrium Chemical Reaction Newtworks2022

    • Author(s)
      小林徹也
    • Organizer
      理研 iTEMSセミナー
    • Invited
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] Chemical Thermodynamics of Growing Systems2022

    • Author(s)
      小林 徹也
    • Organizer
      ICTP-KIAS School on Statistical Physics for Life Sciences
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-19H05794
  • [Presentation] グラフ・ハイパーグラフ上のダイナミクスの情報幾何学2022

    • Author(s)
      小林 徹也
    • Organizer
      JST数学関連3領域連携WS「情報科学と拓く新しい数理科学」
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-19H05794
  • [Presentation] 細胞集団の勾配流と1細胞動態の法則2022

    • Author(s)
      堀口修平, 小林徹也
    • Organizer
      2022年度数理生物学会年会
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] グラフ・ハイパーグラフ上のダイナミクスの情報幾何学2022

    • Author(s)
      小林徹也
    • Organizer
      JST数学関連3領域連携WS「情報科学と拓く新しい数理科学」
    • Invited
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] 前向き後向きBellman方程式による分散型部分観測確率制御の効率化2021

    • Author(s)
      鳥取 岳広, 小林 徹也
    • Organizer
      第 64 回自動制御連合講演会
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] 学習による進化の加速とFisherの基本定理の拡張2021

    • Author(s)
      中島蒼, 小林徹也
    • Organizer
      2021年度日本数理生物学会年会
    • Data Source
      KAKENHI-PROJECT-19H03216
  • [Presentation] 集団動態における生物学的コストとリーマン多様体上の勾配流:免疫系への応用2021

    • Author(s)
      堀口 修平, 小林 徹也
    • Organizer
      2021年度日本数理生物学会年会
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] 生体における化学情報処理機構の定量生物学2021

    • Author(s)
      小林徹也
    • Organizer
      第4回センサ&IoTセミナー
    • Invited
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] Representation and inference of cell growth and division by neural-network-aided point processes2021

    • Author(s)
      上村 淳, 小林徹也
    • Organizer
      日本生物物理学会第59回年次大会
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] Acceleration of evolutionary processes by learning and extended Fisher's fundamental theorem2021

    • Author(s)
      So Nakashima, Tetsuya J. Kobayashi
    • Organizer
      The 20th Congress of the International Union for Pure and Applied Biophysics (IUPAB)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] 単細胞はどこまでよくできているか? 最適フィルター・最適制御理論に基づくバクテリア化学感知機構の最適性の検証2021

    • Author(s)
      小林徹也
    • Organizer
      統計物理と統計科学の連続セミナー
    • Invited
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] Biochemical implementation of optimal control for run-and-tumble chemotaxis2021

    • Author(s)
      Kento Nakamura, Tetsuya J. Kobayashi
    • Organizer
      The 20th Congress of the International Union for Pure and Applied Biophysics (IUPAB)
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] 学習による進化の加速とFisherの基本定理の拡張2021

    • Author(s)
      中島蒼, 小林徹也
    • Organizer
      2021年度日本数理生物学会年会
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] Acceleration of evolutionary processes by learning and extended Fisher's fundamental theorem2021

    • Author(s)
      So Nakashima, Tetsuya J. Kobayashi
    • Organizer
      The 20th Congress of the International Union for Pure and Applied Biophysics (IUPAB)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03216
  • [Presentation] Estimating Bacterial Quantitative Proteomes from Cellular Raman Spectra2021

    • Author(s)
      Ken-ichiro F Kamei, Koseki J Kobayashi-Kirschvink, Hidenori Nakaoka, and Yuichi Wakamoto
    • Organizer
      BPS2021 65th Biophysical Society Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03216
  • [Presentation] Repertoire seqと機械学習2021

    • Author(s)
      小林 徹也
    • Organizer
      第5回理論免疫学ワークショップ
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-19H05794
  • [Presentation] Poisson 点過程と Ginibre 点過程上での連続パーコレーションと 確率論的感染症モデル2021

    • Author(s)
      香取 真知子, 香取 眞理, 小林 徹也
    • Organizer
      2021年度日本数理生物学会年会
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] 推定・制御の最適性に基づくバクテリア化学走性の理解2021

    • Author(s)
      中村絢斗, 小林徹也
    • Organizer
      第 64 回自動制御連合講演会
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] T細胞レパトアデータによる免疫状態の分類手法について2021

    • Author(s)
      堅山 耀太郎, 小林 徹也
    • Organizer
      第6回理論免疫学ワークショップ
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] 機械学習による免疫レパトア分類2021

    • Author(s)
      小林徹也
    • Organizer
      iB Seminar:名古屋大学ハイブリッドセミナー
    • Invited
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] バクテリア化学走性機構の最適性2021

    • Author(s)
      小林徹也
    • Organizer
      2021年日本バイオインフォマティクス学会年会・第十回生命医薬情報連合大会(IIBMP2021)
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] 生命現象をとらえる理論的方法とその展開:情報から構造まで2021

    • Author(s)
      小林徹也
    • Organizer
      東京大学理学部物理学科・2021年度 後期 物理学教室コロキウム
    • Invited
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] Representation and inference of cell growth and division by neural-network-aided point processes2021

    • Author(s)
      上村 淳, 小林徹也
    • Organizer
      日本生物物理学会第59回年次大会
    • Data Source
      KAKENHI-PROJECT-19H03216
  • [Presentation] 機械学習によるシングルセル・ダイナミクスからの生物学的原理の解読2021

    • Author(s)
      小林徹也
    • Organizer
      日本生物物理学会第59回年次大会
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] 細胞集団の勾配流とT細胞分化モデル2021

    • Author(s)
      堀口 修平, 小林 徹也
    • Organizer
      第6回理論免疫学ワークショップ
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] A gradient flow of the heterogeneous cellular population2021

    • Author(s)
      Shuhei A. Horiguchi, Tetsuya J. Kobayashi
    • Organizer
      International Conference on "Emergence of Cooperation and Organization in Groups of Animals and Non-living Objects" (ICMMA 2021)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] 感知ノイズ下の run-and-tumble 型化学走性の最適な制御方式2021

    • Author(s)
      中村絢斗 , 小林徹也
    • Organizer
      2021年度日本数理生物学会年会
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] 生物学における機械学習的アプローチの最先端2020

    • Author(s)
      小林 徹也
    • Organizer
      第43回日本分子生物学会年会
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-19H05794
  • [Presentation] Deciphering latent growth mode of cells from cellular lineage trees2020

    • Author(s)
      小林 徹也
    • Organizer
      Establishing International Research Network of Mathematical Oncology
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-19H05794
  • [Presentation] Optimality of the sensory system of Escherichia coli2020

    • Author(s)
      Kento Nakamura, Tetsuya J. Kobayashi
    • Organizer
      2020 Society of Mathematical Biology Virtual Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] Deciphering latent growth mode of cells from cellular lineage trees2020

    • Author(s)
      Tetsuya J. Kobayashi
    • Organizer
      Establishing International Research Network of Mathematical Oncology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03216
  • [Presentation] 学習理論に基づく胸腺の機能的意義2020

    • Author(s)
      堀口 修平, 小林 徹也
    • Organizer
      第5回理論免疫学ワークショップ
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] 免疫系における胸腺の強化学習の観点からの機能的意義2020

    • Author(s)
      堀口 修平, 小林 徹也
    • Organizer
      2020年度 日本数理生物学会年会
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] 増殖系における個の学習がもつ役割の考察2020

    • Author(s)
      中島蒼, 小林徹也
    • Organizer
      2020年度 日本数理生物学会年会
    • Data Source
      KAKENHI-PROJECT-19H03216
  • [Presentation] 獲得免疫系の定量生物学2020

    • Author(s)
      小林 徹也
    • Organizer
      2020年度 日本数理生物学会年会
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-19H05794
  • [Presentation] Understanding biological sensing and its optimality2020

    • Author(s)
      小林 徹也
    • Organizer
      Universal Principles in Biological Systems and their Evolution
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-19H05794
  • [Presentation] Information processing in cellular systems and the fitness value of information2020

    • Author(s)
      小林 徹也
    • Organizer
      Computational Principles in Active Perception and Reinforcement Learning in the Brain
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-19H05794
  • [Presentation] Lineage EM Algorithm for Inferring Latent States from Cellular Lineage Trees2020

    • Author(s)
      So Nakashima, Yuki Sughiyama, Tetsuya J. Kobayashi
    • Organizer
      2020 Society of Mathematical Biology Virtual Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03216
  • [Presentation] Information processing in cellular systems and the fitness value of information2020

    • Author(s)
      Tetsuya J. Kobayashi
    • Organizer
      Computational Principles in Active Perception and Reinforcement Learning in the Brain
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03216
  • [Presentation] 増殖系における個の学習がもつ役割の考察2020

    • Author(s)
      中島蒼, 小林徹也
    • Organizer
      2020年度 日本数理生物学会年会
    • Invited
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] 生物学における機械学習的アプローチの最先端2020

    • Author(s)
      小林 徹也
    • Organizer
      第43回日本分子生物学会年会
    • Invited
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] Repertoire seqと機械学習2020

    • Author(s)
      小林 徹也
    • Organizer
      第5回理論免疫学ワークショップ
    • Invited
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] 生物学における機械学習的アプローチの最先端2020

    • Author(s)
      小林 徹也
    • Organizer
      第43回日本分子生物学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03216
  • [Presentation] Lineage EM Algorithm for Inferring Latent States from Cellular Lineage Trees2020

    • Author(s)
      So Nakashima, Yuki Sughiyama, Tetsuya J. Kobayashi
    • Organizer
      2020 Society of Mathematical Biology Virtual Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] Deciphering latent growth mode of cells from cellular lineage trees2020

    • Author(s)
      小林 徹也
    • Organizer
      ワークショップ「数理腫瘍学の研究」
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03216
  • [Presentation] 獲得免疫系の定量生物学2020

    • Author(s)
      小林 徹也
    • Organizer
      2020年度 日本数理生物学会年会
    • Invited
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] バクテリア走化性の情報物理学2020

    • Author(s)
      小林 徹也, 中村 絢斗
    • Organizer
      第58回日本生物物理学会年会
    • Invited
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] 増殖系における個の学習がもつ役割の考察2020

    • Author(s)
      小林 徹也
    • Organizer
      2020年度 日本数理生物学会年会
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-19H05794
  • [Presentation] 最適確率制御システムと大腸菌化学走性過程の対応2020

    • Author(s)
      中村絢斗, 小林徹也
    • Organizer
      2020年度 日本数理生物学会年会
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] Deciphering latent growth mode of cells from cellular lineage trees2020

    • Author(s)
      Tetsuya J. Kobayashi
    • Organizer
      Establishing International Research Network of Mathematical Oncology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] 免疫T細胞の抗原識別における確率ノイズの構造2019

    • Author(s)
      梶田 真司, 合原 一幸, 小林 徹也
    • Organizer
      2019年度 日本数理生物学会年会
    • Data Source
      KAKENHI-PUBLICLY-18H05096
  • [Presentation] 情報から捉える生命現象2019

    • Author(s)
      小林 徹也
    • Organizer
      定量生物学の会 北海道キャラバン 2019
    • Data Source
      KAKENHI-PROJECT-19H03216
  • [Presentation] 増殖系と隠れマルコフモデルの対応に基づく学習の考察(A Study on Learning in Growing Population on the Basis of Hidden Markov Model)2019

    • Author(s)
      中島 蒼, 小林 徹也
    • Organizer
      第57回日本生物物理学会年会
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] ライブセルイメージングおよび単一胚移植による産まれる発生パターンの解析2019

    • Author(s)
      小林 徹也
    • Organizer
      有性生殖にかかわる染色体・クロマチン・核動態に関する研究会(遺伝研研究会)
    • Data Source
      KAKENHI-ORGANIZER-19H05794
  • [Presentation] T細胞の分化時間を一定に保つ適応メカニズム2019

    • Author(s)
      金子和正, 小林徹也
    • Organizer
      2019年度 日本数理生物学会年会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-18H05096
  • [Presentation] バクテリアの走化性における濃度変化の推定ダイナミクス2019

    • Author(s)
      中村絢斗, 小林徹也
    • Organizer
      2019年度 日本数理生物学会年会
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] 免疫学習の数理2019

    • Author(s)
      小林 徹也
    • Organizer
      第3回理論免疫学ワークショップ
    • Data Source
      KAKENHI-PUBLICLY-18H05096
  • [Presentation] Understanding adaptive immunity as a reinforcement learning system2019

    • Author(s)
      Tetsuya J. Kobayashi
    • Organizer
      Reinforcement Learning & Biological Intelligence
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H04814
  • [Presentation] 免疫学習の数理2019

    • Author(s)
      小林 徹也
    • Organizer
      第3回理論免疫学ワークショップ
    • Invited
    • Data Source
      KAKENHI-PROJECT-17KT0014
  • [Presentation] 増殖系と隠れマルコフモデルの対応に基づく学習の考察(A Study on Learning in Growing Population on the Basis of Hidden Markov Model)2019

    • Author(s)
      中島 蒼, 小林 徹也
    • Organizer
      第57回日本生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-19H03216
  • [Presentation] 免疫恒常性維持機構への数理的アプローチ2019

    • Author(s)
      小林 徹也
    • Organizer
      細胞ダイバース第四回公開シンポジウム
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-19H05794
  • [Presentation] 強化学習に基づいた適応免疫学習過程のモデル化2019

    • Author(s)
      小林 徹也
    • Organizer
      第9回定量生物学の会 年会
    • Data Source
      KAKENHI-PUBLICLY-18H04814
  • [Presentation] Fitness response relation of a multitype age-structured population dynamics2019

    • Author(s)
      杉山 友規, 中島 蒼, 小林 徹也
    • Organizer
      第57回日本生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-19H03216
  • [Presentation] 免疫細胞多様性の強化学習モデルの解析2019

    • Author(s)
      堀口 修平, 小林 徹也
    • Organizer
      2019年度 日本数理生物学会年会
    • Data Source
      KAKENHI-PUBLICLY-18H05096
  • [Presentation] Understanding adaptive immune system as reinforcement learning2019

    • Author(s)
      小林 徹也
    • Organizer
      Interface between Immunology & Quantitative Biology
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-19H05794
  • [Presentation] 免疫細胞多様性の強化学習モデルの解析2019

    • Author(s)
      堀口 修平, 小林 徹也
    • Organizer
      2019年度 日本数理生物学会年会
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] 免疫恒常性維持機構への数理的アプローチ2019

    • Author(s)
      小林 徹也,金子 和正,秋山 泰身
    • Organizer
      細胞ダイバース第四回公開シンポジウム
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-18H05096
  • [Presentation] 情報から捉える生命現象2019

    • Author(s)
      小林 徹也
    • Organizer
      定量生物学の会 北海道キャラバン 2019
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] 細胞ダイバーシティーへの数理的アプローチ2019

    • Author(s)
      小林 徹也
    • Organizer
      第92回日本生化学会大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03216
  • [Presentation] T細胞の分化時間を一定に保つ適応メカニズム2019

    • Author(s)
      金子和正, 小林徹也
    • Organizer
      2019年度 日本数理生物学会年会
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] 免疫T細胞の抗原識別における確率ノイズの構造2019

    • Author(s)
      梶田 真司, 合原 一幸, 小林 徹也
    • Organizer
      2019年度 日本数理生物学会年会
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] 抗原識別における確率的ノイズの役割(A role of stochastic noise in ligand discrimination)2019

    • Author(s)
      梶田 真司, 合原 一幸, 小林 徹也
    • Organizer
      第57回日本生物物理学会年会
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] Deciphering latent growth mode of cells from cellular lineage trees2019

    • Author(s)
      小林 徹也
    • Organizer
      ワークショップ「数理腫瘍学の研究」
    • Invited
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] マウス着床前発生における細胞数半自動計測法を用いた産仔に繋がる胚の解析2019

    • Author(s)
      小林 徹也
    • Organizer
      第42回日本分子生物学会年会
    • Data Source
      KAKENHI-ORGANIZER-19H05794
  • [Presentation] Fitness response relation of a multitype age-structured population dynamics2019

    • Author(s)
      杉山 友規, 中島 蒼, 小林 徹也
    • Organizer
      第57回日本生物物理学会年会
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] 細胞ダイバーシティーへの数理的アプローチ2019

    • Author(s)
      小林 徹也
    • Organizer
      第92回日本生化学会大会
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-19H05794
  • [Presentation] 細胞ダイバーシティーへの数理的アプローチ2019

    • Author(s)
      小林 徹也
    • Organizer
      第92回日本生化学会大会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-18H05096
  • [Presentation] Information processing in cellular systems and the fitness value of information2019

    • Author(s)
      Tetsuya J. Kobayashi
    • Organizer
      Computational Principles in Active Perception and Reinforcement Learning in the Brain
    • Invited
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] 細胞ダイバーシティーへの数理的アプローチ2019

    • Author(s)
      小林 徹也
    • Organizer
      第92回日本生化学会大会:組織・臓器の構築と制御の統合的理解を目指した細胞ダイバーシティー研究
    • Invited
    • Data Source
      KAKENHI-PLANNED-19H05799
  • [Presentation] 免疫学習の数理2019

    • Author(s)
      小林 徹也
    • Organizer
      第3回理論免疫学ワークショップ
    • Data Source
      KAKENHI-PUBLICLY-18H04814
  • [Presentation] T細胞集団の恒常性と多様性の数理的理解2019

    • Author(s)
      小林 徹也
    • Organizer
      1細胞解析と数理モデリングの融合がもたらす細胞社会ダイバーシティーの理解
    • Invited
    • Data Source
      KAKENHI-PROJECT-17KT0014
  • [Presentation] 抗原識別における確率的ノイズの役割(A role of stochastic noise in ligand discrimination)2019

    • Author(s)
      梶田 真司, 合原 一幸, 小林 徹也
    • Organizer
      第57回日本生物物理学会年会
    • Data Source
      KAKENHI-PUBLICLY-18H05096
  • [Presentation] 情報から捉える生命現象2019

    • Author(s)
      小林 徹也
    • Organizer
      定量生物学の会 北海道キャラバン 2019
    • Data Source
      KAKENHI-ORGANIZER-19H05794
  • [Presentation] A data-driven model for collective cell motion in Dictyostelium discoideum2018

    • Author(s)
      Keizaburo Nishikino, Ryo Yokota, Tetsuya J. Kobayashi
    • Organizer
      第56回日本生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-16H06155
  • [Presentation] Analyzing and modeling of early embryo development2018

    • Author(s)
      Takaaki Matsui, Tetsuya J. Kobayashi
    • Organizer
      第56回日本生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-16H06155
  • [Presentation] 細胞系譜から隠れた増殖モードを推定する2018

    • Author(s)
      小林 徹也
    • Organizer
      第15回 生物数学の理論とその応用 -次世代の数理科学への展開-
    • Data Source
      KAKENHI-PROJECT-16H06155
  • [Presentation] Modeling homeostatic dynamics of thymic T cell development2017

    • Author(s)
      Tetsuya J. Kobayashi
    • Organizer
      Mathematical Innovation for Biomedicine
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17KT0014
  • [Presentation] Theoretical analysis of thymic T cell development dynamics via interaction with thymic epithelial cells2017

    • Author(s)
      Kazumasa Kaneko, Ryo Yokota, Taishin Akiyama, Tetsuya J. Kobayashi
    • Organizer
      EMBL conference Quantitative Principles in Biology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17KT0014
  • [Presentation] A retrospective approach towards population dynamics under fluctuating environment / A retrospective analysis of the muti-state age-structured population dynamics2017

    • Author(s)
      Tetsuya J. Kobayashi, and Yuki Sughiyama
    • Organizer
      Ancestral lines in populations under selection
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06155
  • [Presentation] 胸腺T細胞分化の数理モデリング2017

    • Author(s)
      金子和正, 横田亮, 秋山泰身, 小林徹也
    • Organizer
      第2回理論免疫学WS
    • Invited
    • Data Source
      KAKENHI-PROJECT-17KT0014
  • [Presentation] 胸腺における上皮細胞との相互作用によるT細胞分化制御の理論解析2017

    • Author(s)
      金子和正, 横田亮, 秋山泰身, 小林徹也
    • Organizer
      第1回理論免疫学ワークショップ2017
    • Place of Presentation
      JMSアステールプラザ, 広島
    • Year and Date
      2017-01-19
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K14433
  • [Presentation] サンプル間における T 細胞受容体の定量的レパトア解析2017

    • Author(s)
      横田亮, 神永祐貴,小林徹也
    • Organizer
      定量生物学の会 第八回年会
    • Place of Presentation
      基礎生物学研究所
    • Year and Date
      2017-01-08
    • Data Source
      KAKENHI-PROJECT-15K14433
  • [Presentation] 力学系モデルによる免疫細胞の分化制御プロセスの理論解析2017

    • Author(s)
      金子和正, 横田亮, 秋山泰身, 小林徹也
    • Organizer
      定量生物学の会 第八回年会
    • Place of Presentation
      基礎生物学研究所
    • Year and Date
      2017-01-08
    • Data Source
      KAKENHI-PROJECT-15K14433
  • [Presentation] Mathematical modeling of thymic T cell development via interaction with thymic epithelial cells2017

    • Author(s)
      Kazumasa Kaneko, Ryo Yokota, Taishin Akiyama, Tetsuya J. Kobayashi
    • Organizer
      第46回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-17KT0014
  • [Presentation] Modeling homeostatic dynamics of thymic T cell development2017

    • Author(s)
      Tetsuya J. Kobayashi
    • Organizer
      LyonSysBio 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17KT0014
  • [Presentation] 情報からとらえる生命現象2017

    • Author(s)
      小林 徹也
    • Organizer
      応用物理学会 有機分子・バイオエレクトロニクス分科会2月研究会
    • Place of Presentation
      東京大学駒場第 II キャンパス 生産技術研究所大会議室
    • Year and Date
      2017-02-21
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-15H00800
  • [Presentation] Theoretical analysis of thymic T cell development via interaction with thymic epithelial cells2017

    • Author(s)
      Kazumasa Kaneko, Ryo Yokota, Taishin Akiyama, Tetsuya J. Kobayashi
    • Organizer
      The 2017 (27th) annual meeting of the Japanese Society for Mathematical Biology
    • Data Source
      KAKENHI-PROJECT-17KT0014
  • [Presentation] EM based algorithm to infer both phenotypic state and cell division properties from lineage information2017

    • Author(s)
      So Nakashima, Yuki Sughiyama, Tetsuya J. Kobayashi
    • Organizer
      EMBL conference Quantitative Principles in Biology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06155
  • [Presentation] 定量免疫学に向けて2017

    • Author(s)
      小林 徹也
    • Organizer
      第1回理論免疫学ワークショップ2017
    • Place of Presentation
      JMSアステールプラザ, 広島
    • Year and Date
      2017-01-19
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K14433
  • [Presentation] Modeling and inferring dynamics of T cell population dynamics in thymus2016

    • Author(s)
      Kazumasa Kaneko, Ryo Yokota, Taishin Akiyama, Tetsuya J. Kobayashi
    • Organizer
      第45回日本免疫学会学術集会
    • Place of Presentation
      沖縄コンベンションセンター
    • Year and Date
      2016-12-05
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K14433
  • [Presentation] Discreteness-induced transition in multi-body reaction systems2016

    • Author(s)
      Yohei Saito, Yuki Sughiyama, Kunihiko Kaneko, Tetsuya J. Kobayashi
    • Organizer
      The 2016 (26th) annual meeting of the Japanese Society for Mathematical Biology
    • Place of Presentation
      Shiiki Hall, Kyushu Univ, Fukuoka, Japan
    • Year and Date
      2016-09-07
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-15H00800
  • [Presentation] Quantification of intersample difference in TCR sequences2016

    • Author(s)
      Ryo Yokota, Tetsuya J. Kobayashi
    • Organizer
      第45回日本免疫学会学術集会
    • Place of Presentation
      沖縄コンベンションセンター
    • Year and Date
      2016-12-05
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K14433
  • [Presentation] 免疫細胞の分化プロセスの力学系によるモデリング2016

    • Author(s)
      金子和正, 横田亮, 秋山泰身, 小林徹也
    • Organizer
      生命情報科学若手の会 第8回研究会
    • Place of Presentation
      北海道伊達市大滝セミナーハウスおよび北海道大学
    • Year and Date
      2016-10-12
    • Data Source
      KAKENHI-PROJECT-15K14433
  • [Presentation] Modeling and inferring dynamics of T cell population in thymus2016

    • Author(s)
      Kazumasa Kaneko, Ryo Yokota, Taishin Akiyama, Tetsuya J. Kobayashi
    • Organizer
      The 2016 (26th) annual meeting of the Japanese Society for Mathematical Biology
    • Place of Presentation
      Shiiki Hall, Kyushu Univ, Fukuoka, Japan
    • Year and Date
      2016-09-07
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K14433
  • [Presentation] Modeling and inferring dynamics of T cell population dynamics in thymus2016

    • Author(s)
      Kazumasa Kaneko, Ryo Yokota, Taishin Akiyama, Tetsuya J. Kobayashi
    • Organizer
      生物物理学会 第54回年会
    • Place of Presentation
      つくば国際会議場
    • Year and Date
      2016-11-25
    • Data Source
      KAKENHI-PROJECT-15K14433
  • [Presentation] Discreteness-induced transition in multi-body reaction systems2016

    • Author(s)
      Yohei Saito, Yuki Sughiyama, Tetsuya J. Kobayashi
    • Organizer
      生物物理学会 第54回年会
    • Place of Presentation
      つくば国際会議場
    • Year and Date
      2016-11-25
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-15H00800
  • [Presentation] Steady State Thermodynamics in Population Dynamics2016

    • Author(s)
      Yuki Sughiyama, Tetsuya J. Kobayashi
    • Organizer
      生物物理学会 第54回年会
    • Data Source
      KAKENHI-PROJECT-16H06155
  • [Presentation] Quantification of the intersample difference in T cell population2016

    • Author(s)
      Ryo Yokota, Yuki Kaminaga, Tetsuya J. Kobayashi
    • Organizer
      生物物理学会 第54回年会
    • Place of Presentation
      つくば国際会議場
    • Year and Date
      2016-11-25
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K14433
  • [Presentation] Statistical analysis shows non-randomness of V/J gene selection in human TCR.2015

    • Author(s)
      Yotaro Katayama, Ryo Yokota, Tetsuya J. Kobayashi
    • Organizer
      The 44th Annual Meetings of The Japanese Society for Immunology
    • Place of Presentation
      札幌コンベンションセンター(北海道)
    • Year and Date
      2015-11-18
    • Data Source
      KAKENHI-PROJECT-15K14433
  • [Presentation] Systems-Biological Approaches for TCR Repertoire Analysis2015

    • Author(s)
      Tetsuya J. Kobayashi
    • Organizer
      The 44th Annual Meetings of The Japanese Society for Immunology
    • Place of Presentation
      札幌コンベンションセンター(北海道)
    • Year and Date
      2015-11-18
    • Data Source
      KAKENHI-PROJECT-15K14433
  • [Presentation] ミクロな細胞システムにおけるゆらぎと確率的情報処理2014

    • Author(s)
      小林徹也
    • Organizer
      続日本ゆらぎ現象研究会
    • Place of Presentation
      東京工業大学, 東京
    • Invited
    • Data Source
      KAKENHI-PLANNED-21116006
  • [Presentation] Information Decoding in Microscopic Biological Processes2013

    • Author(s)
      T.J. Kobayashi
    • Organizer
      35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
    • Data Source
      KAKENHI-PLANNED-21116006
  • [Presentation] Analysis of changes in Epigenetic gene expression by single cell2013

    • Author(s)
      Masaya Oki, Tetsuya. J. Kobayashi
    • Organizer
      酵母からのエピジェネティクス研究へのメッセージ; ~酵母が明らかにする生命科学の最先端~
    • Place of Presentation
      グランディア芳泉,福井
    • Invited
    • Data Source
      KAKENHI-PLANNED-21116006
  • [Presentation] 大局的細胞移動推定及び局所的相対位置関係類似度を用いた密な状態における3次元細胞トラッキング2013

    • Author(s)
      備瀬竜馬、佐藤洋一、近藤晶子、小林徹也、大沼清
    • Organizer
      第16回画像の認識・理解シンポジウムMIRU2013
    • Place of Presentation
      国立情報学研究所、東京
    • Data Source
      KAKENHI-PROJECT-25460258
  • [Presentation] Dynamic Information Processing in Biological Sensing Systems2013

    • Author(s)
      Tetsuya J. Kobayashi
    • Organizer
      Nonlinear Theory and Its Applications (NOLTA) 2013
    • Place of Presentation
      Santa Fe, US
    • Invited
    • Data Source
      KAKENHI-PLANNED-21116006
  • [Presentation] Single-cell Stochastic Dynamics of Epigenetic Regulation in Yeast2013

    • Author(s)
      小林 徹也
    • Organizer
      NGS現場の会 第三回研究会
    • Place of Presentation
      神戸国際会議場,神戸
    • Data Source
      KAKENHI-PLANNED-21116006
  • [Presentation] Information Decoding in Microscopic Biological Processes2013

    • Author(s)
      Tetsuya J. Kobayashi
    • Organizer
      35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
    • Place of Presentation
      Osaka International Convension Center, Osaka, Japan
    • Invited
    • Data Source
      KAKENHI-PLANNED-21116006
  • [Presentation] Dynamic Information Processing in Biological Sensing Systems2013

    • Author(s)
      T. J. Kobayashi
    • Organizer
      Nonlinear Theory and Its Applications 2013
    • Data Source
      KAKENHI-PLANNED-21116006
  • [Presentation] Information-theoretical Approach for Biological Sensing Phenomena2013

    • Author(s)
      Tetsuya J. Kobayashi
    • Organizer
      iCeMS One-Day Symposium on Theoretical and Computational Biology
    • Place of Presentation
      iCeMs, Kyoto
    • Invited
    • Data Source
      KAKENHI-PLANNED-21116006
  • [Presentation] Analyzing Stochastic Dynamics of Cellular & Multi-cellular Systems2013

    • Author(s)
      Kobayashi
    • Organizer
      The 61th NIBB Conference "Cellular Community in Mammalian Embryogenesis"
    • Place of Presentation
      Okazaki Conference Center, Aichi, Japan
    • Invited
    • Data Source
      KAKENHI-PLANNED-21116006
  • [Presentation] 密な状況での細胞群の3次元追跡2013

    • Author(s)
      備瀬竜馬、佐藤洋一、近藤晶子、小林徹也、大沼清
    • Organizer
      第13回東京大学生命科学シンポジウム
    • Place of Presentation
      東京大学本郷キャンパス、東京
    • Data Source
      KAKENHI-PROJECT-25460258
  • [Presentation] Role of Adaptive Dynamics in Stochastic Cellular Sensing Systems2013

    • Author(s)
      小林 徹也
    • Organizer
      第51回日本生物物理学会年会
    • Place of Presentation
      国立京都国際会館
    • Invited
    • Data Source
      KAKENHI-PLANNED-21116006
  • [Presentation] Dynamics of Bayesian Inference and its Application to Cellular Decision-Making2013

    • Author(s)
      T.J. Kobayashi
    • Organizer
      Information, probability and inference in systems biology (IPISB 2013)
    • Data Source
      KAKENHI-PLANNED-21116006
  • [Presentation] Nuclear Centroids and Volumes Extraction from Four Dimensional Fluorescence Images: A Preliminary Study for Embryo Condition Assessment2013

    • Author(s)
      Khayrul Bashar, Kazuo Yamagata, Tetsuya J. Kobayashi
    • Organizer
      35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
    • Place of Presentation
      Osaka International Convension Center, Osaka, Japan
    • Data Source
      KAKENHI-PLANNED-21116006
  • [Presentation] Nuclei Identification from Fluorescence Images using Graph Mining2013

    • Author(s)
      Khayrul Bashar, Kazuo Yamagata, Tetsuya J. Kobayashi
    • Organizer
      35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
    • Place of Presentation
      Osaka International Convension Center, Osaka, Japan
    • Data Source
      KAKENHI-PLANNED-21116006
  • [Presentation] "Dynamics of Bayesian Inference and its Application to Cellular Decision-Making"2013

    • Author(s)
      Tetsuya J. Kobayashi
    • Organizer
      Information, probability and inference in systems biology (IPISB 2013)
    • Place of Presentation
      ICMS, Edinburgh, UK,
    • Invited
    • Data Source
      KAKENHI-PLANNED-21116006
  • [Presentation] Bayesian Information Processing in Stochastic Biological Systems2013

    • Author(s)
      T.J. Kobayashi
    • Organizer
      International Conference of Noise and Fluctuation 2013
    • Place of Presentation
      Montpellier, France
    • Data Source
      KAKENHI-PLANNED-21116006
  • [Presentation] 情報ダイナミクスの生命科学2012

    • Author(s)
      小林徹也
    • Organizer
      生命医薬情報学連合大会 - 情報計算化学生物学会
    • Place of Presentation
      タワーホール船堀
    • Invited
    • Data Source
      KAKENHI-PLANNED-21116006
  • [Presentation] 細胞システムにおける確率的情報処理2012

    • Author(s)
      小林徹也
    • Organizer
      システム分子行動学 数理シンポジウム
    • Place of Presentation
      東京大学
    • Invited
    • Data Source
      KAKENHI-PLANNED-21116006
  • [Presentation] Detection of Three Dimensional Centroids of Cell Nuclei from Fluorescence Microscopy Images2012

    • Author(s)
      Md. Khayrul Bashar, Koji Komatsu, Toshihiko Fujimori, and Tetsuya J. Kobayashi
    • Organizer
      CDB Symposium 2012 Quantitative Developmental Biology
    • Place of Presentation
      Riken, Kobe, Japan
    • Data Source
      KAKENHI-PLANNED-21116006
  • [Presentation] Segmenting Cell Nuclei from Three Dimensional Fluorescence Microscopy Images2012

    • Author(s)
      Md. Khayrul Bashar, Koji Komatsu, Toshihiko Fujimori, and Tetsuya J. Kobayashi
    • Organizer
      Joint symposium by JST/BBSRC(UK) Molecular Imaging and Systems Biology
    • Place of Presentation
      University of Tokyo, Japan
    • Data Source
      KAKENHI-PLANNED-21116006
  • [Presentation] Bayesian Approach for Cellular Information Processing2012

    • Author(s)
      Tetsuya J. Kobayashi
    • Organizer
      Dynamic Days Asia Pacific 7
    • Place of Presentation
      Taipei, Taiwan
    • Invited
    • Data Source
      KAKENHI-PLANNED-21116006
  • [Presentation] 細胞システムにおける確率的情報処理の数理2012

    • Author(s)
      小林徹也
    • Organizer
      情報統計力学の最前線 ―確率が繋ぐ自然現象と情報処理の数理―
    • Place of Presentation
      東北大学
    • Invited
    • Data Source
      KAKENHI-PLANNED-21116006
  • [Presentation] 情報ダイナミクスの生命科学2012

    • Author(s)
      小林徹也
    • Organizer
      生命医薬情報学連合大会 -情報計算化学生物学会
    • Data Source
      KAKENHI-PLANNED-21116006
  • [Presentation] Statistical approach towards intracellular information processing2012

    • Author(s)
      Tetsuya J. Kobayashi
    • Organizer
      Workshop on Applied Physics and Statistics for Quantitative Biology
    • Place of Presentation
      The Institute of Statistical Mathematics, Research and Organization of Information and Systems, JAPAN
    • Invited
    • Data Source
      KAKENHI-PLANNED-21116006
  • [Presentation] 生体システムにおける情報ダイナミクス2012

    • Author(s)
      小林徹也
    • Organizer
      ネットワーク構造と生命現象
    • Place of Presentation
      JR博多シティ 大会議室
    • Invited
    • Data Source
      KAKENHI-PLANNED-21116006
  • [Presentation] Improved detection of cell centroids from fluorescence images by adaptive filtering2012

    • Author(s)
      Md. Khayrul Bashar, Koji Komatsu, Toshihiko Fujimori, and Tetsuya J. Kobayashi
    • Organizer
      International conference of Systems Biology 2012
    • Place of Presentation
      Univ. Toronto,Toronto, Canada
    • Data Source
      KAKENHI-PLANNED-21116006
  • [Presentation] Mathematical modeling for cost-effective cell-cell communication2012

    • Author(s)
      Tomoyuki Yamada, Atsushi Kamimura, Tetsuya J. Kobayashi
    • Organizer
      International Symposium on Artificial Life and Robotics 17th '12
    • Place of Presentation
      Beppu, Japan
    • Data Source
      KAKENHI-PLANNED-21116006
  • [Presentation] Three dimensional cell nuclei extraction from fluorescence microscopy images using locally adaptive threshold2011

    • Author(s)
      M.K.Bashar, K.Komatsu, Tetesuya J.Kobayashi, T.Fujimori
    • Organizer
      ICSB2011 Workshop Microscopic Image Analysis with Applications in Biology (MIAAB'2011)
    • Place of Presentation
      ドイツ・ハイデルベルグ
    • Year and Date
      2011-09-02
    • Data Source
      KAKENHI-PLANNED-21116006
  • [Presentation] 定量的な生命科学と情報・数理技術2011

    • Author(s)
      小林徹也
    • Organizer
      第84回日本生化学会大会
    • Data Source
      KAKENHI-PLANNED-21116006
  • [Presentation] バイオイメージインフォマティクス~理論生物学・定量生物学の視点から~2011

    • Author(s)
      小林徹也
    • Organizer
      バイオイメージ・インフォマティクス ワークショップ2011
    • Place of Presentation
      理化学研究所横浜研究所交流棟ホール(交流棟1階)
    • Year and Date
      2011-01-28
    • Data Source
      KAKENHI-PLANNED-21116006
  • [Presentation] 細胞間信号伝達におけるコミュニケーションコストの数理的解析2011

    • Author(s)
      山田智之, 上村淳, 小林徹也
    • Organizer
      第21回 日本数理生物学会 年会
    • Place of Presentation
      明治大学リバティータワー
    • Data Source
      KAKENHI-PLANNED-21116006
  • [Presentation] バイオイメージングと画像情報処理の技術 : 定量的な解析にむけて2011

    • Author(s)
      小林徹也
    • Organizer
      日本顕微鏡学会第55回シンポジウム
    • Data Source
      KAKENHI-PLANNED-21116006
  • [Presentation] Mathematical analysis of cost-effective cell-cell communication(コストを考慮した細胞間コミュニケーションの数理的解析)2011

    • Author(s)
      山田智之, 上村淳, 小林徹也
    • Organizer
      第49回 生物物理学会 年会
    • Place of Presentation
      兵庫県立大学姫路書写キャンパス
    • Data Source
      KAKENHI-PLANNED-21116006
  • [Presentation] Detecting Nuclei-centroids of Mouse Embryonic Cells from Fluorescence Microscopy Images2011

    • Author(s)
      M.K.Bashar, K.Komatsu, Tetesuya J.Kobayashi, T.Fujimori
    • Organizer
      International conference of Systems Biology 2011
    • Place of Presentation
      ドイツ・ハイデルベルグ
    • Year and Date
      2011-08-30
    • Data Source
      KAKENHI-PLANNED-21116006
  • [Presentation] バイオイメージングと画像情報処理の技術:定量的な解析にむけて2011

    • Author(s)
      小林 徹也
    • Organizer
      日本顕微鏡学会第55回シンポジウム
    • Place of Presentation
      サンポート高松 かがわ国際会議場
    • Invited
    • Data Source
      KAKENHI-PLANNED-21116006
  • [Presentation] GPGPUを用いたバイオイメージの高速画像処理2011

    • Author(s)
      舟橋啓, 太田信之, 小林徹也, 広井賀子
    • Organizer
      バイオイメージ・インフォマティクスワークショップ2011
    • Place of Presentation
      理化学研究所横浜研究所
    • Year and Date
      2011-01-28
    • Data Source
      KAKENHI-PLANNED-21116006
  • [Presentation] 定量的な生命科学と情報・数理技術2011

    • Author(s)
      小林 徹也
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      国立京都国際会館
    • Invited
    • Data Source
      KAKENHI-PLANNED-21116006
  • [Presentation] 定量的な生命科学とバイオイメージング2010

    • Author(s)
      小林徹也
    • Organizer
      第19回日本バイオイメージング学会学術集会
    • Data Source
      KAKENHI-PLANNED-21116006
  • [Presentation] 細胞機能としての情報処理2010

    • Author(s)
      小林徹也
    • Organizer
      分子生物学会年会
    • Data Source
      KAKENHI-PLANNED-21116006
  • [Presentation] Towards Automatic Cell Segmentation and Tracking Using Fluorescence Microscopy Images2010

    • Author(s)
      M.K.Bashar, T.J.Kobayashi
    • Organizer
      定量生物学の会 第三回年会
    • Place of Presentation
      東京大学・生産技術研究所
    • Year and Date
      2010-11-27
    • Data Source
      KAKENHI-PLANNED-21116006
  • [Presentation] 定量的な生命科学とバイオイメージング2010

    • Author(s)
      小林徹也
    • Organizer
      第19回 日本バイオイメージング学会学術集会
    • Place of Presentation
      慶應義塾大学 日吉キャンパス来往舎
    • Year and Date
      2010-09-10
    • Data Source
      KAKENHI-PLANNED-21116006
  • [Presentation] 画像解析によるin vivo細胞内粒子運動の統計的性質の解析2010

    • Author(s)
      小林徹也, 舟橋啓, 春本敏之, 太田信之, 上田泰己, 上村匡
    • Organizer
      MIRU2010 Workshop:細胞内画像処理
    • Place of Presentation
      釧路・釧路市国際交流センター
    • Year and Date
      2010-07-26
    • Data Source
      KAKENHI-PLANNED-21116006
  • [Presentation] AUTOMATIC SEGMENTATION OF ABDOMINAL BLOOD VESSELS FROM CONTRASTED X-RAY CT IMAGES2010

    • Author(s)
      M.K.Bashar, K.Mori, T.J.Kobayashi
    • Organizer
      6th International Conference on Electrical & Computer Engineering (ICECE) 2010
    • Place of Presentation
      Dhaka, Bangladesh
    • Year and Date
      2010-12-18
    • Data Source
      KAKENHI-PLANNED-21116006
  • [Presentation] 3D Cell Tracking under dense cell culture conditions by preserving the structure of neighbor cells

    • Author(s)
      Ryoma Bise, Yoichi Sato, Akiko Kondow, Tetsuya J. Kobayashi, Kiyoshi Ohnuma
    • Organizer
      IEEE International Symposium on Biomedical Imaging (ISBI) 2014
    • Place of Presentation
      北京、中華人民共和国
    • Year and Date
      2014-04-29 – 2014-05-02
    • Data Source
      KAKENHI-PROJECT-25460258
  • 1.  FUJIMORI Toshihiko (80301274)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 2.  FUNAHASHI Akira (70324548)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 3.  KONDOW Akiko (90396838)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 4.  OHNUMA Kiyoshi (50396834)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 5.  NONAKA Shigenori (90435529)
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  • 6.  Yokota Ryo (80733154)
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    # of Collaborated Products: 11 results
  • 7.  SASAKI Hiroshi (10211939)
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  • 8.  MENO Chikara (20311764)
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  • 9.  SUZUKI Atsushi (00264606)
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  • 10.  HIROI Noriko (20548408)
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    # of Collaborated Products: 3 results
  • 11.  HONDA Hisao (10289118)
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  • 12.  NAKAYA Yukiko (70415256)
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    # of Collaborated Products: 0 results
  • 13.  Hori Shohei (50392113)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  SATO Yoichi (70302627)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 15.  YAMAMURA Masayuki (00220442)
    # of Collaborated Projects: 1 results
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  • 16.  KONAGAYA Akihiko (00301200)
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  • 17.  SUZUKI Yasuhiro (50292983)
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  • 18.  MOCHIZUKI Atsushi (10304726)
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  • 19.  TAKAYASU Misako (20296776)
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  • 20.  ONO Isao (20078166)
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  • 21.  ITO Hiroshi (20512627)
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  • 22.  SEKINE Ryoji (70730232)
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    # of Collaborated Products: 0 results
  • 23.  秋山 泰身 (50327665)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 24.  若本 祐一 (30517884)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 25.  岡田 康志 (50272430)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  佐々 真一 (30235238)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 27.  石島 秋彦 (80301216)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  沙川 貴大 (60610805)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  伊藤 創祐 (00771221)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  澤井 哲 (20500367)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  竹内 一将 (50622304)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  川口 喬吾 (00787319)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  青木 一洋 (80511427)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  松岡 里実 (00569733)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  神原 丈敏 (40451637)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  福岡 創 (50447190)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 37.  榎 佐和子 (50467635)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 38.  池崎 圭吾 (10722960)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 39.  蔡 栄淑 (40378716)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 40.  森下 喜弘 (00404062)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 41.  岩城 光宏 (30432503)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 42.  猪股 秀彦 (60372166)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 43.  中島 昭彦 (90612119)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 44.  Katayama Yotaro
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 45.  Kaminaga Yuki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 46.  Kaneko Kazumasa
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 47.  Kajita Masashi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 48.  YAMAGATA kazuo
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 49.  秋山 伸子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 50.  上村 淳
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 4 results
  • 51.  杉山 友規
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 52.  好村 滋行
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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