Yamashita Motozo 山下元三

… Alternative Names

YAMASHITA Motozo 山下元三

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Researcher Number	90524984
Other IDs
Affiliation (Current)	2025: 大阪大学, 歯学部附属病院, 講師
Affiliation (based on the past Project Information) *help	2017 – 2024: 大阪大学, 歯学部附属病院, 講師 2016: 大阪大学, 歯学研究科, 助教 2009 – 2015: Osaka University, 歯学部附属病院, 助教 2013: 大阪大学, 歯学附属病院, 助教 2011: 大阪大学, 歯学研究科, 助教
Review Section/Research Field	Principal Investigator Periodontal dentistry / Medium-sized Section 57:Oral science and related fields / Periodontology / Basic Section 57030:Conservative dentistry-related Except Principal Investigator Medium-sized Section 57:Oral science and related fields / Periodontology / Basic Section 57030:Conservative dentistry-related / Dental engineering/Regenerative dentistry / Periodontal dentistry / Basic Section 57040:Regenerative dentistry and dental engineering-related
Keywords	Principal Investigator 歯周病 / 歯根膜細胞 / 細胞老化 / 老化 / エピジェネティクス / 加齢 / 歯学 / 歯根膜老化制御薬剤 / 老化歯周組織 / 高齢者 … More / 糖尿病 / 相分離 / ネオエピゲノム歯周病治療 / 液相分離 / DNAトポイソメラーゼー / DNAのねじれ / BRD4 / エンハンサー / 炎症 / ATACシークエンス / サイトカインストーム / スーパーエンハンサー / DNA超らせん / エピゲノム / 歯周病治療 / senolytic / NAD+中間代謝産物 / 時計遺伝子 / NAMPT / SIRT / 時間制御 / 老化制御 / 老化細胞 / ミトコンドリア / NMN / NAD+依存性 / MicroRNAs / インフラマエイジング / トランスオミクス / MicroRNA / 細部老化 / エクソソーム / microRNAs / 慢性炎症 / マイクロRNA / SASP / 幹細胞 / ECM蛋白 / 非対称性細胞分裂 / ニッチェ / 歯周組織幹細胞 / オートファジ- / オートファジー / 歯周組織 / 細胞内大規模蛋白分解 / ユビキチン化システム / シグナルクロストーク / 歯周外科学 / シグナル伝達 … More Except Principal Investigator 歯根膜細胞 / 歯周病 / 歯根膜 / ゲノムワイドアプローチ / 歯周組織再生 / 疾患関連遺伝子 / 侵襲性歯周炎 / シングルセル解析 / 骨芽細胞 / リン酸カルシウム / 石灰化過程 / 石灰化 / 老化 / エクソームシークエンス / GWAS / 組織再生 / 歯周組織 / FGF-2 / バイオインフォマティクス / 分子疫学 / 転写因子 / キメラ分子 / 分子接着剤 / PROTAC / 口腔 / 高齢者 / エピゲノム / 長期縦断研究 / 歯 / 双子研究 / オートファジー / フォールディング / コラーゲン / プロテオスタシス / CXCR4/SDF-1 / microRNA / 細胞老化 / ソーティング / ラマン分光 / ラマンスペクトル / ラマン分光法 / 細胞外基質 / 誘電率顕微鏡 / 基質小胞 / 硬組織 / RNA Velocity / ヒエラルキー / trajectory / 運命決定 / 細胞系譜 / セメント芽細胞 / 幹細胞 / 系譜解析 / ノックインマウス / 組織幹細胞 / プロテオーム解析 / メタボローム解析 / オミクス解析 / CLSPN / LIPA / SNP / エクソームシークエンス解析 / オルガネラ / ミトコンドリア / リソソーム / オルガネラ間相互作用 / ステムセルエイジング / 歯学 / CRISPR/Cas9 / ゲノム編集 / Chemical screening / 遺伝子改変マウス / 長寿研究 / PON1 / Ebelactone B / カテプシンA / 細胞由来マイクロパーティクルマイクロパーティクル / 細胞由来マイクロパーティクル / マイクロパーティクル / FGF－２ / オステオインテグレーション / インプラント / 歯科疾患感受性 / エピジェネティクス / 受動喫煙 / 喫煙 / 再生医療 / 再生療法 Less

Regulation of Periodontal Tissue Aging - A Novel Strategy for Overcoming Periodontal Disease and Diabetes in the Elderly-Principal Investigator
- Principal Investigator
  
  山下元三
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Osaka University
分子接着剤を用いた超効率的な組織再生誘導
- Principal Investigator
  
  岩山智明
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Osaka University
CXCR4/SDF-1 axis ameliorates the impaired wound healing and tissue regeneration in aged periodontal tissue
- Principal Investigator
  
  池上久仁子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Osaka University
歯根膜コラーゲンのプロテオスタシス制御に基づく新規歯周治療法の開発
- Principal Investigator
  
  中村友美
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Osaka University
Longitudinal study of oral health and systemic disease in older identical twins
- Principal Investigator
  
  池邉一典
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Osaka University
Enhancement of Single Cell Analysis of Periodontal Ligament by Raman Spectroscopy Sorting
- Principal Investigator
  
  Takedachi Masahide
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Osaka University
Creation of neo-epigenetic periodontal therapy targeting DNA twistPrincipal Investigator
- Principal Investigator
  
  Yamashita Motozo
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Osaka University
Role of interorganelle communication in mineralization
- Principal Investigator
  
  Iwayama Tomoaki
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Osaka University
Understanding of pathogenesis of aggressive periodontitis by omics data
- Principal Investigator
  
  Shinya Murakami
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Osaka University
Analysis of cellular hierarchy in the periodontal ligament
- Principal Investigator
  
  Iwayama Tomoaki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Osaka University
Nano-level multimodal analysis of matrix vesicle-mediated biomineralization
- Principal Investigator
  
  Murakami Shinya
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Osaka University
Extension of healthy longevity in body and periodontal tissue by NMN supplementation and senolytic treatmentPrincipal Investigator
- Principal Investigator
  
  YAMASHITA MOTOZO
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Osaka University
Challenge to the development of new treatments applying the enhancement of periodontal tissue regeneration by controlling stem cell aging
- Principal Investigator
  
  Kitamura Masahiro
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57040:Regenerative dentistry and dental engineering-related
- Research Institution
  Osaka University
Development of time controlled therapy for aged periodontal tissue.Principal Investigator
- Principal Investigator
  
  YAMASHITA MOTOZO
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Periodontology
- Research Institution
  Osaka University
Feasible research for novel periodontal regeneration therapeutics by CRISPR/Cas9
- Principal Investigator
  
  YAMADA Satoru
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Periodontology
- Research Institution
  Tohoku University
  Osaka University
Analysis of micro RNA-34a in senescent periodontal ligament cells.
- Principal Investigator
  
  Ikegami Kuniko
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Periodontology
- Research Institution
  Osaka University
Effects of cathepsin A on the regeneration of periodontal ligament tissue
- Principal Investigator
  
  Kitagaki Jirouta
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontology
- Research Institution
  Osaka University
Identification of genetic risk factors of aggressive periodontitis by genome wide approach
- Principal Investigator
  
  Murakami Shinya
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Periodontology
- Research Institution
  Osaka University
The effect of cell-derived microparticles on the homeostasis of periodontal tissue
- Principal Investigator
  
  Yanagita Manabu
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontology
- Research Institution
  Osaka University
Analysis of SASP in chronic periodontal diseasePrincipal Investigator
- Principal Investigator
  
  YAMASHITA MOTOZO
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Periodontology
- Research Institution
  Osaka University
Asymmetric stem cell division in the homeostasis and the disease onset of periodontal tissuePrincipal Investigator
- Principal Investigator
  
  YAMASHITA MOTOZO
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Osaka University
On demand regulation of tissue regenerative environment at the recipient site of transplantation therapy and dental implant
- Principal Investigator
  
  NOZAKI Takenori
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dental engineering/Regenerative dentistry
- Research Institution
  Osaka University
Development of predictive periodontology based on molecular epidemiological study
- Principal Investigator
  
  MURAKAMI Shinya
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Osaka University
A Challenge to the expansion of indications in periodontal tissue regeneration using FGF-2 by analyzing cross talk between signal molecules
- Principal Investigator
  
  KITAMURA Masahiro
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Dental engineering/Regenerative dentistry
- Research Institution
  Osaka University
Passive smoking-induced epigenetic regulation in tooth・periodontal tissue-associated genes.
- Principal Investigator
  
  KITAMURA Masahiro
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Periodontal dentistry
- Research Institution
  Osaka University
Defective autophagy in aged periodontal tissuePrincipal Investigator
- Principal Investigator
  
  YAMASHITA Motozo
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Periodontal dentistry
- Research Institution
  Osaka University
Ubiquitin-proteasome system regulates cytokine signal crosstalk in periodontal stem cellsPrincipal Investigator
- Principal Investigator
  
  YAMASHITA Motozo
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Osaka University

All 2023 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 Other

All Journal Article Presentation

[Journal Article] Cellular senescence with SASP in periodontal ligament cells triggers inflammation in aging periodontal tissue2023
- Author(s)
  Kuniko Ikegami, Motozo Yamashita, Mio Suzuki, Tomomi Nakamura, Koki Hashimoto, Jirouta Kitagaki, Manabu Yanagita, Masahiro Kitamura, Shinya Murakami
- Journal Title
  
  Aging
  
  Volume: 15(5) Pages: 1279-1305
- DOI
  10.18632/aging.204569
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09963, KAKENHI-PROJECT-22K09979
[Journal Article] Autophagy facilitates type I collagen synthesis in periodontal ligament cells2021
- Author(s)
  Nakamura Tomomi、Yamashita Motozo、Ikegami Kuniko、Suzuki Mio、Yanagita Manabu、Kitagaki Jirouta、Kitamura Masahiro、Murakami Shinya
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 1-14
- DOI
  10.1038/s41598-020-80275-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21674, KAKENHI-PROJECT-20K18532, KAKENHI-PROJECT-20K18534
[Journal Article] 老化と慢性炎症　ー歯周組織の慢性炎症2021
- Author(s)
  山下元三、村上伸也
- Journal Title
  
  別冊　BIO Clinica 慢性炎症と疾患
  
  Volume: Vol.10 No.2 Pages: 41-46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21674
[Journal Article] Long-term exposure to cigarette smoke influences characteristics in human gingival fibroblasts2021
- Author(s)
  Mari Tatsumi, Manabu Yanagita, Motozo Yamashita, Shiori Hasegawa, Kuniko Ikegami, Masahiro Kitamura, Shinya Murakami
- Journal Title
  
  J Periodontal Res
  
  Volume: 56(5) Issue: 5 Pages: 951-963
- DOI
  10.1111/jre.12891
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21674, KAKENHI-PROJECT-20K18534
[Journal Article] Periodontal inflamed surface area is associated with hs-CRP in septuagenarian Japanese adults in cross-sectional findings from the SONIC study2021
- Author(s)
  Koji Miki, Masahiro Kitamura, Kodai Hatta, Kei Kamide, Yasuyuki Gondo, Motozo Yamashita, Masahide Takedachi, Takenori Nozaki, Chiharu Fujihara, Yoichiro Kashiwagi et al
- Journal Title
  
  Sci Rep
  
  Volume: 11(1) Issue: 1 Pages: 14436-14436
- DOI
  10.1038/s41598-021-93872-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21674, KAKENHI-PROJECT-17H02633, KAKENHI-PROJECT-20K07803
[Journal Article] Aromatase inhibitor anastrozole modifies cellular functions in gingival fibroblasts and endothelial cells: possible periodontal complications of aromatase inhibitor treatment2021
- Author(s)
  Shiori Hasegawa Manabu Yanagita Mari Tatsumi Motozo Yamashita Masahiro Kitamura, Shinya Murakami
- Journal Title
  
  Journal of Periodontal Research
  
  Volume: － Issue: 4 Pages: 828-836
- DOI
  10.1111/jre.12881
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21674
[Journal Article] Association of periodontal disease with atherosclerosis in 70-year-old Japanese older adults2020
- Author(s)
  Kitamura M, Ikebe K, Kamide K, Gondo Y, Yamashita M, Takedachi M, Nozaki T, Fujihara C, Yamada S, Kashiwagi Y, Miki K, Iwayama T, Hatta K, Mihara Y, Kurushima Y et al
- Journal Title
  
  Odontology
  
  Volume: 109 Issue: 2 Pages: 506-513
- DOI
  10.1007/s10266-020-00567-z
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02982, KAKENHI-PROJECT-19H01069
[Journal Article] Clinical Outcome of Periodontal Tissue Regeneration Therapy by Administration of Basic Fibroblast Growth Factor (FGF-2)2020
- Author(s)
  沢田啓吾北村正博長谷川詩織森本千晶平井麻絵今井昂川嵜公輔橋本康樹麻生桃子辻井翔一野田亜利紗花田滉輔政近健司藤田翔子鈴木美麻八木寛子池上久仁子山本智美森健太中村友美小笹匡雄北垣次郎太岩山智明柏木陽一郎藤原千春三木康史竹立匡秀山下元三野崎剛徳村上伸也
- Journal Title
  
  The Japanese Journal of Conservative Dentistry
  
  Volume: 63 Issue: 3 Pages: 219-227
- DOI
  10.11471/shikahozon.63.219
- NAID
  130007871208
- ISSN
  0387-2343, 2188-0808
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K18534, KAKENHI-PROJECT-18H02982
[Journal Article] Response to "Genetics of Periodontitis without Bias".2019
- Author(s)
  Masumoto R, Kitagaki J, Fujihara C, Matsumoto M, Miyauchi S, Asano Y, Imai A, Kobayashi K, Nakaya A, Yamashita M, Yamada S, Kitamura M, Murakami S
- Journal Title
  
  The Journal of Periodontal Research
  
  Volume: 54(5) Issue: 5 Pages: 455-456
- DOI
  10.1111/jre.12652
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H01069
[Journal Article] Response to “Identification of Genetic Risk Factors of Aggressive Periodontitis Using Genome-Wide Association Studies in Association with Those of Chronic Periodontitis.”2019
- Author(s)
  Masumoto R, Kitagaki J, Fujihara C, Matsumoto M, Miyauchi S, Asano Y, Imai A, Kobayashi K, Nakaya A, Yamashita M, Yamada S, Kitamura M, Murakami S.
- Journal Title
  
  J Periodontal Res.
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H02579
[Journal Article] Identification of genetic risk factors of aggressive periodontitis using genomewide association studies in association with those of chronic periodontitis.2018
- Author(s)
  Masumoto R, Kitagaki J, Fujihara C, Matsumoto M, Miyauchi S, Asano Y, Imai A, Kobayashi K, Nakaya A, Yamashita M, Yamada S, Kitamura M, Murakami S.
- Journal Title
  
  J Periodontal Res.
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H02579
[Journal Article] Sphingomyelin Phosphodiesterase 3 Enhances Cytodifferentiation of Periodontal Ligament Cells2017
- Author(s)
  S Miyauchi, J Kitagaki, R Masumoto, A Imai, K Kobayashi, A Nakaya, S Kawai, C Fujihara, Y Asano, M Yamashita, M Yanagita, S Yamada, M Kitamura, S. Murakami
- Journal Title
  
  J Dent Res
  
  Volume: 96 Issue: 3 Pages: 339-46
- DOI
  10.1177/0022034516677938
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H02579, KAKENHI-PROJECT-15K11385, KAKENHI-PROJECT-16K11828, KAKENHI-PROJECT-15K09139
[Journal Article] Effects of paraoxonase 1 on the cytodifferentiation and mineralization of periodontal ligament cells.2017
- Author(s)
  R Masumoto, J Kitagaki, M Matsumoto, S Miyauchi, C Fujihara, M Yamashita, S Yamada, M Kitamura, S Murakami.
- Journal Title
  
  J Periodont Res
  
  Volume: 53(2) Issue: 2 Pages: 200-209
- DOI
  10.1111/jre.12507
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H02579, KAKENHI-PROJECT-17H04416, KAKENHI-PROJECT-15K11385
[Journal Article] A Putative Association of a Single Nucleotide Polymorphism in GPR126 with Aggressive Periodontitis in a Japanese Population2016
- Author(s)
  Kitagaki J, Miyauchi S, Asano Y, Imai A, Kawai S, Michikami I, Yamashita M, Yamada S, Kitamura M, Murakami S
- Journal Title
  
  PLoS One
  
  Volume: 11 Issue: 8 Pages: e0160765-e0160765
- DOI
  10.1371/journal.pone.0160765
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H02579, KAKENHI-PROJECT-15K09139, KAKENHI-PROJECT-15K11385
[Journal Article] he effects of cigarette smoke condensate and nicotine on periodontal tissue in a periodontitis model mouse.2016
- Author(s)
  Kubota M, Yanagita M, Mori K, Hasegawa S, Yamashita M, Yamada S, Kitamura M, Murakami S.
- Journal Title
  
  PLoS One
  
  Volume: 11 Issue: 5 Pages: e0155594-e0155594
- DOI
  10.1371/journal.pone.0155594
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26463133
[Journal Article] Transcriptome Reveals Cathepsin K in Periodontal Ligament Differentiation.2016
- Author(s)
  Yamada S, Ozaki N, Tsushima K, Yamaba S, Fujihara C, Awata T, Sakashita H, Kajikawa T, Kitagaki J, Yamashita M, Yanagita M, Murakami S
- Journal Title
  
  J Dent Res
  
  Volume: 95 Issue: 9 Pages: 1026-33
- DOI
  10.1177/0022034516645796
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H02579, KAKENHI-PROJECT-26293437
[Journal Article] IFN-β Expression via TLR3 in Human Gingival Epithelial Cells in the Presence of Nicotine2016
- Author(s)
  柳田学
- Journal Title
  
  The Japanese Journal of Conservative Dentistry
  
  Volume: 59 Issue: 1 Pages: 93-102
- DOI
  10.11471/shikahozon.59.93
- NAID
  130005129178
- ISSN
  0387-2343, 2188-0808
- Language
  Japanese
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26463133
[Journal Article] Transcriptome reveals cathepsin K in periodontal ligament differentiation2016
- Author(s)
  S Yamada, N Ozaki, K Tsushima, S Yamaba, C Fujihara, T Awata, H Sakashita, T Kajikawa, J Kitagaki, M Yamashita, M Yanagita, S Murakami
- Journal Title
  
  J Dent Res
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H02579
[Journal Article] TGF-beta negatively regulates the BMP2-dependent early commitment of periodontal ligament cells into hard tissue forming cells2015
- Author(s)
  T Kawahara, M Yamashita, K Ikegami, T Nakamura, M Yanagita, S Yamada, M Kitamura, S Murakami
- Journal Title
  
  PLOS ONE
  
  Volume: in press
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390466
[Journal Article] Influence of genetic and environmental factors on oral diseases and function in aged twins2015
- Author(s)
  Y Kurushima, K Ikebe*, K Matsuda, K Enoki, S Ogata, M Yamashita, S Murakami, K Hayakawa, Y Maeda
- Journal Title
  
  J of Oral Rehabilitation
  
  Volume: 42 Issue: 1 Pages: 49-56
- DOI
  10.1111/joor.12228
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23249086, KAKENHI-PROJECT-25670884, KAKENHI-PROJECT-26293151, KAKENHI-PROJECT-26462918
[Journal Article] TGF-beta negatively regulates the BMP2-dependent early commitment of periodontal ligament cells into hard tissue forming cells2015
- Author(s)
  T Kawahara, M Yamashita, K Ikegami, T Nakamura, M Yanagita, S Yamada, M Kitamura, S Murakami
- Journal Title
  
  PLOS ONE
  
  Volume: in press
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25670884
[Journal Article] PLAP-1/asporin positively regulates FGF-2 activity2015
- Author(s)
  T Awata, S Yamada, K Tsushima, H Sakashita, S Yamaba, T Kajikawa, M Yamashita, M Takedachi, M Yanagita, M Kitamura, S Murakami.
- Journal Title
  
  J Dent Res
  
  Volume: 94 Issue: 10 Pages: 1417-24
- DOI
  10.1177/0022034515598507
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H02579, KAKENHI-PROJECT-26893146, KAKENHI-PROJECT-26293437
[Journal Article] Effects of proteasome inhibitor bortezomib on cytodifferentiation and mineralization of periodontal ligament cells2014
- Author(s)
  J Kitagaki, S Miyauchi1, C Xie, M Yamashita, S Yamada, M Kitamura, S Murakami.
- Journal Title
  
  J Periodont Res
  
  Volume: 50 Issue: 2 Pages: 248-255
- DOI
  10.1111/jre.12202
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390466, KAKENHI-PROJECT-25670884, KAKENHI-PROJECT-25862045
[Journal Article] 歯根膜細胞の石灰化過程におけるTGF-βシグナルの役割2013
- Author(s)
  山下元三、河原貴展、村上伸也
- Journal Title
  
  日本歯周病学会会誌
  
  Volume: 55 Pages: 132-139
- NAID
  10031183908
- Data Source
  KAKENHI-PROJECT-24390466
[Journal Article] 歯根膜細胞の石灰化過程における TGF-・eta シグナルの役割2013
- Author(s)
  山下元三、河原貴展、村上伸也
- Journal Title
  
  日本歯周病学会会誌
  
  Volume: 第55巻2号(印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659976
[Journal Article] 歯根膜細胞の石灰化過程におけるTGF-βシグナルの役割2013
- Author(s)
  山下元三、河原貴展、村上伸也
- Journal Title
  
  日本歯周病学会会誌
  
  Volume: 55-2 Pages: 132-139
- NAID
  10031183908
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670884
[Journal Article] A tumor suppressor function of Smurf2 associated with controlling chromatin landscape and genome stability through RNF202012
- Author(s)
  Blank M, Tang Y, Yamashita M, Burkett SS, Cheng SY, Zhang YE
- Journal Title
  
  Nat Med
  
  Volume: 18(2) Issue: 2 Pages: 227-234
- DOI
  10.1038/nm.2596
- Data Source
  KAKENHI-PROJECT-23659976
[Journal Article] A tumor suppressor function of Smurf2 associated with controlling chromatin landscape and genome stability through RNF202012
- Author(s)
  Blank M, Tang Y, Yamashita M, Burkett SS, Cheng SY, Zhang YE
- Journal Title
  
  Nat Med
  
  Volume: 18(2) Pages: 227-234
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689053
[Journal Article] Ablation of Smurf2 reveals an inhibition in TGF-β signalling through multiple mono-ubiquitination of Smad3.2011
- Author(s)
  Tang LY, Yamashita M, Coussens NP, Tang Y, Wang X, Li C, Deng CX, Cheng SY, Zhang YE
- Journal Title
  
  EMBO J.
  
  Volume: 30(23) Issue: 23 Pages: 4777-89
- DOI
  10.1038/emboj.2011.393
- Data Source
  KAKENHI-PROJECT-23659976
[Journal Article] Ablation of Smurf2 reveals an inhibition in TGF-βsignalling through multiple mono-ubiquitination of Smad32011
- Author(s)
  Tang LY, Yamashita M, Coussens NP, Tang Y, Wang X, Li C, Deng CX, Cheng SY, Zhang YE
- Journal Title
  
  EMBO J
  
  Volume: 30(23) Pages: 4777-4789
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689053
[Journal Article] A negative feedback control of TGF-beta signaling by GSK3-mediated Smad3 linker phosphorylation at Ser2042009
- Author(s)
  山下元三
- Journal Title
  
  J Biol Chem. 284(30)
  
  Pages: 19808-19816
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689053
[Presentation] 早老症Werner症候群患者の歯周病治療2023
- Author(s)
  池上久仁子、山下元三、川口美紅、吉田悠作、板橋光輝、我妻奈都子、北村正博、村上伸也
- Organizer
  第66回秋季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-22K09963
[Presentation] NAD+依存性のミトコンドリアの異常が老化歯根膜における酸化ストレスに及ぼす影響2021
- Author(s)
  橋本　康樹，山下　元三，池上　久仁子，中村　友美，西川　有彩，森川　竜也，北村　正博，村上　伸也
- Organizer
  第64回秋季日本歯周病学会総会
- Data Source
  KAKENHI-PROJECT-20K21674
[Presentation] HSP47 causes the denatured collagen in aged periodontal ligament.2021
- Author(s)
  Arisa Nishikawa, Motozo Yamashita and Shinya Murakami
- Organizer
  第69回国際歯科研究学会日本部会学術大会(JADR)(国際学会)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21674
[Presentation] Roles of HSPs for Type 1 Collagen Synthesis in HPDL Cells2020
- Author(s)
  A. Nishikawa, M.Yamashita, M. Suzuki, K. Ikegami, T. Nakamura, K. Hashimoto, T. Morikawa, M. Kitamura, S. Murakami
- Organizer
  98th General Session & Exhibition of the IADR
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02982
[Presentation] Genetic and Environmental Factors on Periodontitis in Elderly Twins.2020
- Author(s)
  Ikegami K, Yamashita M, Miki K, Nishikawa A, Hashimoto K, Morikawa T, Takeshita N, Ikebe K, Kitamura M and Murakami S.
- Organizer
  106th Annual Meeting American Academy of Periodontology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02982
[Presentation] 歯根膜細胞の分化過程におけるCGRPの機能解析2020
- Author(s)
  竹下登、三木康史、山下元三、北村正博、村上伸也
- Organizer
  第63回秋季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-18H02982
[Presentation] Analysis of Mitophagy in Senescent HPDL Cell.2019
- Author(s)
  Yamashita M, Suzuki M, Ikegam K, Nakamura T, Nishikawa A, Hashimoto K, Morikawa T, Miki K, Yanagita M, Kitamura M, Shinya Murakami.
- Organizer
  13th Asian Pacific Society of Periodontology Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02982
[Presentation] NMN Improves the Accumulation of ROS in Senescent HPDL Cells2019
- Author(s)
  Hashimoto K, Yamashita M, Suzuki M, Ikegami K, Nakamura T, Nishikawa A, Morikawa T, Kitamura M, Murakami S
- Organizer
  4th Meeting of the International Association for Dental Research Asia Pacific Region 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04416
[Presentation] 老化ヒト歯根膜細胞における活性酸素産生に及ぼすマイトファジーの役割2019
- Author(s)
  鈴木美麻，山下元三，池上久仁子，中村友美，西川有彩，橋本康樹，北村正博，村上伸也
- Organizer
  日本歯科保存学会春季学術大会（第150回）
- Data Source
  KAKENHI-PROJECT-18H02982
[Presentation] 老化ヒト歯根膜細胞における活性酸素産生に及ぼすマイトファジーの役割2019
- Author(s)
  鈴木美麻，山下元三，池上久仁子，中村友美，西川有彩，橋本康樹，北村正博，村上伸也
- Organizer
  日本歯科保存学会春季学術大会（第150回）
- Data Source
  KAKENHI-PROJECT-18K19644
[Presentation] NMN Improves the Accumulation of ROS in Senescent HPDL Cells2019
- Author(s)
  Hashimoto K, Yamashita M, Suzuki M, Ikegami K, Nakamura T, Nishikawa A, Morikawa T, Kitamura M, Murakami S
- Organizer
  4th Meeting of the International Association for Dental Research Asia Pacific Region 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02982
[Presentation] 老化ヒト歯根膜細胞における活性酸素産生に及ぼすマイトファジーの役割2019
- Author(s)
  鈴木美麻，山下元三，池上久仁子，中村友美，西川有彩，橋本康樹，北村正博，村上伸也
- Organizer
  日本歯科保存学会春季学術大会（第150回）
- Data Source
  KAKENHI-PROJECT-17H04416
[Presentation] MiR-34a Regutates Stem Cell Aging in Periodontal ligament Stem Cells.2019
- Author(s)
  Ikegami K, Yamashita M, Suzuki M, Nishikawa A, Hashimoto K, Nakamura T, Miki K, Yanagita M, Kitamura M, Murakami S.
- Organizer
  13th Asian Pacific Society of Periodontology Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02982
[Presentation] MiR-34a Regutates Stem Cell Aging in Periodontal ligament Stem Cells.2019
- Author(s)
  Ikegami K, Yamashita M, Suzuki M, Nishikawa A, Hashimoto K, Nakamura T, Miki K, Yanagita M, Kitamura M, Murakami S.
- Organizer
  13th Asian Pacific Society of Periodontology Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04416
[Presentation] Activation of HSPs Ameliorates the Collagen Production in HPDL Cells2019
- Author(s)
  Nishikawa A, Yamashita M, Suzuki M, Ikegami K, Nakamura T, Hashimoto K, Morikawa T, Kitamura M, Murakami S
- Organizer
  4th Meeting of the International Association for Dental Research Asia Pacific Region 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02982
[Presentation] Analysis of Mitophagy in Senescent HPDL Cell.2019
- Author(s)
  Yamashita M, Suzuki M, Ikegam K, Nakamura T, Nishikawa A, Hashimoto K, Morikawa T, Miki K, Yanagita M, Kitamura M, Shinya Murakami.
- Organizer
  13th Asian Pacific Society of Periodontology Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19644
[Presentation] 大阪大学歯学部附属病院（口腔治療・歯周科）における塩基性線維芽細胞（FGF-2）製剤を用いた歯周組織再生療法の治療実績2019
- Author(s)
  長谷川詩織、北村正博、今井昴、川嵜公輔、橋本康樹、花田滉輔、麻生桃子、野田亜利紗、辻井翔一、政近健司、藤田翔子、鈴木美麻、平井麻絵、森本千晶、八木寛子、池上久仁子、沢田啓吾、中村友美、岩山智明、柏木陽一郎、藤原千春、三木康史、竹立匡秀、山下元三、野崎剛徳、村上伸也
- Organizer
  第151回秋季日本保存学会
- Data Source
  KAKENHI-PROJECT-18H02982
[Presentation] Activation of HSPs Ameliorates the Collagen Production in HPDL Cells2019
- Author(s)
  Nishikawa A, Yamashita M, Suzuki M, Ikegami K, Nakamura T, Hashimoto K, Morikawa T, Kitamura M, Murakami S
- Organizer
  4th Meeting of the International Association for Dental Research Asia Pacific Region 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04416
[Presentation] Analysis of Mitophagy in Senescent HPDL Cell.2019
- Author(s)
  Yamashita M, Suzuki M, Ikegam K, Nakamura T, Nishikawa A, Hashimoto K, Morikawa T, Miki K, Yanagita M, Kitamura M, Shinya Murakami.
- Organizer
  13th Asian Pacific Society of Periodontology Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04416
[Presentation] NMN Improves the Accumulation of ROS in Senescent HPDL Cells2019
- Author(s)
  Hashimoto K, Yamashita M, Suzuki M, Ikegami K, Nakamura T, Nishikawa A, Morikawa T, Kitamura M, Murakami S
- Organizer
  4th Meeting of the International Association for Dental Research Asia Pacific Region 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19644
[Presentation] Activation of HSPs Ameliorates the Collagen Production in HPDL Cells2019
- Author(s)
  Nishikawa A, Yamashita M, Suzuki M, Ikegami K, Nakamura T, Hashimoto K, Morikawa T, Kitamura M, Murakami S
- Organizer
  4th Meeting of the International Association for Dental Research Asia Pacific Region 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19644
[Presentation] Impairment of mitophagy in senescent HPDL cells2018
- Author(s)
  Mio SUZUKI, Motozo YAMASHITA, Kuniko IKEGAMI, Tomomi NAKAMURA, Koji MIKI, Manabu YANAGITA, Masahiro KITAMURA, Shinya MURAKAMI
- Organizer
  96th IADR
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02982
[Presentation] Identification of Genetic Risk Factors for Aggressive Periodontitis2018
- Author(s)
  Risa Masumoto, Jirouta Kitagaki, Masahiro Matsumoto, Chiharu Fujihara, Motozo Yamashita, Satoru Yamada, Masahiro Kitamura, Shinya Murakami
- Organizer
  96th General Session of the IADR
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02579
[Presentation] Optical dissection of the mitophagy dynamics in HPDL cells2018
- Author(s)
  Motozo Yamashita, Mio Suzuki, Kuniko Ikegami, Tomomi Nakamura, Arisa Nishikawa, Koji Miki, Manabu Yanagita, Masahiro Kitamura, Shinya Murakami
- Organizer
  AAP 104th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02982
[Presentation] Senescence-associated miR-34a accelerates periodontal stem-cell aging by targeting SATB22018
- Author(s)
  Kuniko Ikegami, Motozo Yamashita, Mio Suzuki, Arisa Nishikawa, Tomomi Nakamura, Koji Miki, Jirouta Kitagaki, Manabu Yanagita, Masahiro Kitamura and Shinya Murakami
- Organizer
  American Academy of Periodontology (AAP) 104th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04416
[Presentation] Optical dissection of the mitophagy dynamics in HPDL cells.2018
- Author(s)
  Motozo Yamashita, Mio Suzuki, Kuniko Ikegami, Tomomi Nakamura, Arisa Nishikawa, Koji Miki, Manabu Yanagita, Masahiro Kitamura, Shinya Murakami
- Organizer
  American Academy of Periodontology (AAP) 104th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04416
[Presentation] Dissection of the mitophagy dynamics in HPDL cells by fluorescent probe.2018
- Author(s)
  Mio Suzuki, Motozo Yamashita, Kuniko Ikegami, Tomomi Nakamura, Arisa Nishikawa, Kouki Hashimoto, Koji Miki, Manabu Yanagita, Masahiro Kitamura, Shinya Murakami
- Organizer
  第66回国際歯科研究学会日本部会総会・学術大会
- Data Source
  KAKENHI-PROJECT-17H04416
[Presentation] Senescence-associated miR-34a suppress osteoblastic differentiation in periodontal stem cell2018
- Author(s)
  Kuniko Ikegami, Motozo Yamashita, Mio Suzuki, Arisa Nishikawa, Tomomi Nakamura, Koji Miki, Manabu Yanagita, Masahiro Kitamura, Shinya Murakami
- Organizer
  66th JADR
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02982
[Presentation] Impairment of mitophagy in senescent HPDL cells.2018
- Author(s)
  Mio SUZUKI, Motozo YAMASHITA, Kuniko IKEGAMI, Tomomi NAKAMURA, Koji MIKI, Manabu YANAGITA, Masahiro KITAMURA, Shinya MURAKAMI
- Organizer
  96th General Session and Exhibition of the IADR
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04416
[Presentation] 老化歯根膜細胞におけるマイトファジーの機能解析2018
- Author(s)
  山下元三、鈴木美麻、池上久仁子、西川有梨沙、橋本康樹、柳田学、北村正博、村上伸也
- Organizer
  第18回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-17H04416
[Presentation] タバコ煙の長期曝露が歯肉線維芽細胞の細胞機能に及ぼす影響2018
- Author(s)
  辰巳真理、柳田学、長谷川詩織、鈴木美麻、池上久仁子、山下元三、北村正博、村上伸也
- Organizer
  第61回春季日本歯周病学会
- Data Source
  KAKENHI-PROJECT-18H02982
[Presentation] ヒト老化歯根膜細胞におけるmicroRNA-34a -SATB2を介した硬組織形成制御2017
- Author(s)
  池上久仁子、山下元三、鈴木美麻、三木康史、北垣次郎太、柳田学、北村正博、村上伸也
- Organizer
  日本炎症・再生医学会
- Data Source
  KAKENHI-PROJECT-16H06962
[Presentation] Exome Sequencing of Aggressive Periodontitis in a Japanese Population2017
- Author(s)
  S Miyauchi, J Kitagaki, R Masumoto, M Yamashita, M Yanagita, S Yamada, M Kitamura, S Murakami
- Organizer
  2017　IADR　GENERAL　SESSION
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02579
[Presentation] ヒト老化歯根膜細胞におけるマイトファジーの機能低下2017
- Author(s)
  鈴木　美麻，山下　元三，池上　久仁子，中村　友美，柳田　学，野崎　剛徳，山田　聡，北村　正博，村上　伸也
- Organizer
  第６０回　春季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-15H02579
[Presentation] Failure of mitophagy in senescent HPDL cells2017
- Author(s)
  M Suzuki, M Yamashita, K Ikegami, T Nakamura, K Miki, M Yanagita, M Kitamura, S Murakami
- Organizer
  第65回国際歯科研究学会日本部会総会・学術大会　JADR2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04416
[Presentation] ヒト老化歯根膜細胞におけるmicroRNA-34a-SATB2を介した硬組織形成制御2017
- Author(s)
  池上　久仁子，山下　元三，鈴木　美麻，三木　康史，北垣　次郎太，柳田　学，北村　正博，村上　伸也
- Organizer
  第38回日本炎症・再生医学会
- Data Source
  KAKENHI-PROJECT-17H04416
[Presentation] ヒト老化歯根膜細胞におけるマイトファジーの機能低下2017
- Author(s)
  山下元三、鈴木美麻、池上久仁子、中村友美、西川有彩、北村正博、村上伸也
- Organizer
  第40回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H04416
[Presentation] Possible mechanism of aromatase-inhibitor induces gingival overgrowth2017
- Author(s)
  Shiori Hasegawa, Manabu Yanagita, Mikiko Kubota, Motozo Yamashita, Masahiro Kitamura, Shinya Murakami
- Organizer
  2017 IADR GENERAL SESSION
- Place of Presentation
  San Francisco, California (USA)
- Year and Date
  2017-03-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02579
[Presentation] Genetic Risk Factor for Aggressive Periodontitis in a Japanese Population2017
- Author(s)
  R Masumoto, J Kitagaki, M Matsumoto, C Fujihara, M Yamashita, S Yamada, M Kitamura, S Murakami
- Organizer
  第65回国際歯科研究学会日本部会総会・学術大会　JADR2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02579
[Presentation] Exome Sequencing of Aggressive Periodontitis in a Japanese Population2017
- Author(s)
  Shizuka Miyauchi, Jirouta Kitagaki, Risa Masumoto, Motozo Yamashita, Manabu Yanagita, Satoru Yamada, Masahiro Kitamura, Shinya Murakami
- Organizer
  2017 IADR GENERAL SESSION
- Place of Presentation
  San Francisco, California, USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11385
[Presentation] Analysis of pathomolecular condition of periodontitis with Loeys-Dietz Syndrome2017
- Author(s)
  K Tsushima, S Yamada, T Awata, S Yamaba, H Sakashita, M Kinoshita, M Takedachi, J Kitagaki, M Yamashita, M Yanagita, T Nozaki, M Kitamura, M Saito, S Murakami
- Organizer
  2017　IADR　GENERAL　SESSION
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02579
[Presentation] Exome Sequencing of Aggressive Periodontitis in a Japanese Population2017
- Author(s)
  Shizuka Miyauchi, Jirouta Kitagaki, Risa Masumoto, Motozo Yamashita, Manabu Yanagita, Satoru Yamada, Masahiro Kitamura, Shinya Murakami
- Organizer
  2017 IADR GENERAL SESSION
- Place of Presentation
  San Francisco, California (USA)
- Year and Date
  2017-03-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02579
[Presentation] ゲノムワイドアプローチを用いた日本人における侵襲性歯周炎の疾患関連遺伝子探索2017
- Author(s)
  桝本　梨沙、北垣　次郎太、松本　昌大、宮内　静香、小笹　匡雄、東山　弥生、竹立　匡秀、藤原　千春、山下　元三、山田　聡、北村　正博、村上　伸也
- Organizer
  第147回歯科保存学会秋季学術大会
- Data Source
  KAKENHI-PROJECT-15H02579
[Presentation] 歯根膜細胞の骨芽細胞への分化におけるparaoxonase 1の役割2017
- Author(s)
  北垣次郎太、枡本梨沙、松本昌大、宮内静香、藤原千春、山下元三、山田聡、北村正博、村上伸也
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-15K11385
[Presentation] 歯周組織の老化性炎症におけるmicroRNA-34aの役割2017
- Author(s)
  池上久仁子、山下元三、鈴木美麻、山本智美、沢田啓吾、森健太、粟田敏仁、大原廣之、柏木陽一郎、小笹匡雄、竹立匡秀、北垣次郎太、柳田学、野崎剛徳、山田聡、北村正博、村上伸也
- Organizer
  日本再生医療学会
- Data Source
  KAKENHI-PROJECT-16H06962
[Presentation] Analysis of cellular senescence in periodontal disease2017
- Author(s)
  Motozo Yamashita
- Organizer
  THE 7TH JAPAN-THAILAND KOREA JOINT SYMPOSIUM
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04416
[Presentation] 日本人における侵襲性歯周炎の疾患関連遺伝子探索2017
- Author(s)
  桝本　梨沙、北垣　次郎太、松本　昌大、宮内　静香、藤原　千春、黒田　智子、田内　拓史、小笹　匡雄、柏木　陽一郎、沢田　啓吾、山下　元三、柳田　学、竹立　匡秀、山田　聡、野崎　剛徳、北村　正博、村上　伸也
- Organizer
  第60回　秋季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-17H04416
[Presentation] 歯周組織の老化性炎症におけるmicroRNA-34aの役割2017
- Author(s)
  池上久仁子、山下元三、鈴木美麻、山本智美、沢田啓吾、森健太、粟田敏仁、大原廣之、柏木陽一郎、小笹匡雄、竹立匡秀、北垣次郎太、柳田学、野崎剛徳、山田聡、北村正博、村上伸也
- Organizer
  第16回　日本再生医療学会総会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2017-03-07
- Data Source
  KAKENHI-PROJECT-16H06962
[Presentation] ヒト老化歯根膜細胞におけるmicroRNA-34a SATB2を介した硬組織形成制御2017
- Author(s)
  池上　久仁子、山下　元三、中村　友美、鈴木　美麻、西川　有彩、平沼　麻央、三木　康史、北垣　次郎太、柳田　学、北村　正博、村上　伸也
- Organizer
  第147回歯科保存学会秋季学術大会
- Data Source
  KAKENHI-PROJECT-15H02579
[Presentation] Hypoxia　affects Extracellular Matrix Productionin Periodontal Cells2017
- Author(s)
  Chiaki Morimoto, Masahide Takedachi, Satomi Yamamoto, Keigo Sawada, Asae Hirai, Tomoaki Iwayama, Tomomi Nakamura, Motozo Yamashita and Shinya Murakami
- Organizer
  2017 IADR GENERAL SESSION
- Place of Presentation
  San Francisco, California (USA)
- Year and Date
  2017-03-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02579
[Presentation] ゲノムワイドアプローチを用いた日本人における侵襲性歯周炎の疾患関連遺伝子探索2017
- Author(s)
  桝本　梨沙、北垣　次郎太、松本　昌大、宮内　静香、小笹　匡雄、東山　弥生、竹立　匡秀、藤原　千春、山下　元三、山田　聡、北村　正博、村上　伸也
- Organizer
  第147回歯科保存学会秋季学術大会
- Data Source
  KAKENHI-PROJECT-17H04416
[Presentation] ヒト老化歯根膜細胞におけるmicro-RNA-34a SATB2を介した硬組織形成制御2017
- Author(s)
  池上　久仁子、山下　元三、中村　友美、鈴木　美麻、西川　有彩、平沼　麻央、三木　康史、北垣　次郎太、柳田　学、北村　正博、村上　伸也
- Organizer
  第60回　秋季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-17H04416
[Presentation] 日本人における侵襲性歯周炎の疾患関連遺伝子探索2017
- Author(s)
  桝本　梨沙、北垣　次郎太、松本　昌大、宮内　静香、藤原　千春、黒田　智子、田内　拓史、小笹　匡雄、柏木　陽一郎、沢田　啓吾、山下　元三、柳田　学、竹立　匡秀、山田　聡、野崎　剛徳、北村　正博、村上　伸也
- Organizer
  第60回　秋季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-15H02579
[Presentation] 歯根膜の老化性炎症における細胞老化の役割2016
- Author(s)
  池上久仁子、山下元三、鈴木美麻、柳田学、野崎剛徳、山田聡、北村正博、村上伸也
- Organizer
  第59回秋季日本歯周病学会学術大会
- Place of Presentation
  朱鷺メッセ（新潟県新潟市）
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-16H06962
[Presentation] Genome-wide Association Study of Aggressive Periodontitis in a Japanese Population2016
- Author(s)
  Shizuka MIYAUCHI, Jirouta KITAGAKI, Motozo YAMASHITA, Satoru YAMADA, Masahiro KITAMURA, Shinya MURAKAMI
- Organizer
  2016 IADR GENERAL SESSION
- Place of Presentation
  Seoul, Korea
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02579
[Presentation] ゲノムワイドアプローチによる日本人侵襲性歯周炎の疾患関連遺伝子探索2016
- Author(s)
  宮内静香、北垣次郎太、山下元三、山田聡、北村正博、村上伸也
- Organizer
  第144回日本歯科保存学会2016年度春季学術大会
- Place of Presentation
  栃木県総合文化センター（栃木県宇都宮市）
- Data Source
  KAKENHI-PROJECT-15K11385
[Presentation] マウス実験的歯周炎モデルにおけるタバコ煙濃縮物およびニコチンの影響2016
- Author(s)
  久保田実木子、柳田学、長谷川詩織、森健太、山下元三、山田聡、北村正博、村上伸也
- Organizer
  第144回春季日本歯科保存学会
- Place of Presentation
  栃木県総合文化センター、栃木県、宇都宮市
- Year and Date
  2016-06-09
- Data Source
  KAKENHI-PROJECT-26463133
[Presentation] 歯根膜細胞の骨芽細胞分化に対するSMPD3の効果2016
- Author(s)
  北垣次郎太、宮内静香、枡本梨沙、藤原千春、山下元三、柳田学、山田聡、北村正博、村上伸也
- Organizer
  第145回日本歯科保存学会2016年度秋季学術大会
- Place of Presentation
  キッセイ文化ホール（長野県松本市）
- Data Source
  KAKENHI-PROJECT-15K11385
[Presentation] 低酸素状態が歯肉線維芽細胞のコラーゲン産生に及ぼす影響2016
- Author(s)
  森本千晶、竹立匡秀、山本智美、平井麻絵、沢田啓吾、中村友美、山下元三、村上伸也
- Organizer
  第59回春季日本歯周病学会学術大会
- Place of Presentation
  かごしま県民交流センター（鹿児島県鹿児島市）
- Data Source
  KAKENHI-PROJECT-15H02579
[Presentation] The effects of aromatase inhibitor on gingival cells2016
- Author(s)
  Shiori HASEGAWA, Manabu YANAGITA, Mikiko KUBOTA, Motozo YAMASHITA, Masahiro KITAMURA, Shinya MURAKAMI
- Organizer
  2016 IADR GENERAL SESSION
- Place of Presentation
  Seoul, Korea
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02579
[Presentation] アロマターゼ阻害薬が歯周組織構成細胞に及ぼす影響2016
- Author(s)
  長谷川詩織、柳田学、久保田実木子、山下元三、北村正博、村上伸也
- Organizer
  第59回春季日本歯周病学会学術大会
- Place of Presentation
  かごしま県民交流センター（鹿児島県鹿児島市）
- Data Source
  KAKENHI-PROJECT-15H02579
[Presentation] microRNA-34a によるヒト歯根膜細胞の老化制御2016
- Author(s)
  山下元三、池上久仁子、鈴木美麻、柳田学、山田聡、北村正博、村上伸也
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16H06962
[Presentation] 歯根膜細胞の骨芽細胞分化に対するSMPD3の効果2016
- Author(s)
  北垣次郎太、宮内静香、枡本梨沙、藤原千春、山下元三、柳田学、山田聡、北村正博、村上伸也
- Organizer
  第145回日本歯科保存学会2016年度秋季学術大会
- Place of Presentation
  キッセイ文化ホール（長野県松本市）
- Data Source
  KAKENHI-PROJECT-15H02579
[Presentation] Genome-wide Association Study of Aggressive Periodontitis in a Japanese Population2016
- Author(s)
  Shizuka MIYAUCHI, Jirouta KITAGAKI, Motozo YAMASHITA, Satoru YAMADA, Masahiro KITAMURA, Shinya MURAKAMI
- Organizer
  2016 IADR GENERAL SESSION
- Place of Presentation
  Seoul, Korea
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11385
[Presentation] 歯根膜細胞の骨芽細胞分化におけるSMPD3の影響2016
- Author(s)
  北垣次郎太、宮内静香、桝本梨沙、今井敦子、小林香織、中谷明弘、河合伸治、藤原千春、山下元三、柳田学、山田聡、北村正博、村上伸也
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Data Source
  KAKENHI-PROJECT-15K11385
[Presentation] 歯周病に関与する遺伝因子と環境因子の検討－双生児研究からの解析－2016
- Author(s)
  三木康史、山下元三、池上久仁子、鈴木美麻、久留島悠子、池邉一典、北村正博、前田芳信、村上伸也
- Organizer
  第23回　日本歯科医学会
- Place of Presentation
  福岡国際会議場（福岡県福岡市）
- Year and Date
  2016-10-23
- Data Source
  KAKENHI-PROJECT-16H06962
[Presentation] ゲノムワイドアプローチによる日本人侵襲性歯周炎の疾患関連遺伝子探索2016
- Author(s)
  宮内静香、北垣次郎太、山下元三、山田聡、北村正博、村上伸也
- Organizer
  第144回日本歯科保存学会2016年度春季学術大会
- Place of Presentation
  栃木県総合文化センター（栃木県宇都宮市）
- Data Source
  KAKENHI-PROJECT-15H02579
[Presentation] アロマターゼ阻害薬が歯周組織構成細胞に及ぼす影響2016
- Author(s)
  長谷川詩織、柳田学、久保田実木子、山下元三、北村正博、村上伸也
- Organizer
  第59回春季日本歯周病学会
- Place of Presentation
  鹿児島県民交流センター、鹿児島県、鹿児島市
- Year and Date
  2016-05-20
- Data Source
  KAKENHI-PROJECT-26463133
[Presentation] タバコ煙濃縮物およびニコチンの全身投与がマウス実験的歯周炎の病態形成に及ぼす影響2016
- Author(s)
  久保田実木子、柳田学、長谷川詩織、辰巳真理、山下元三、山田聡、北村正博、村上伸也
- Organizer
  第145回秋季日本歯科保存学会
- Place of Presentation
  キッセイ文化ホール、長野県、松本市
- Year and Date
  2016-10-28
- Data Source
  KAKENHI-PROJECT-26463133
[Presentation] 歯根膜細胞の骨芽細胞分化におけるSMPD3の影響2016
- Author(s)
  北垣次郎太、宮内静香、桝本梨沙、今井敦子、小林香織、中谷明弘、河合伸治、藤原千春、山下元三、柳田学、山田聡、北村正博、村上伸也
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Data Source
  KAKENHI-PROJECT-15H02579
[Presentation] 歯根膜細胞における非神経性コリン作動系の発現2016
- Author(s)
  三木康史、山下元三、柳田学、北村正博、村上伸也
- Organizer
  第145回秋季日本歯科保存学会
- Place of Presentation
  キッセイ文化ホール、長野県、松本市
- Year and Date
  2016-10-28
- Data Source
  KAKENHI-PROJECT-26463133
[Presentation] The Effects of Hypoxia on Collagen Production in Gingival Fibroblasts2016
- Author(s)
  Chiaki MORIMOTO, Masahide TAKEDACHI, Satomi YAMAMOTO, Asae HIRAI, Keigo SAWADA, Tomoaki IWAYAMA, Tomomi NAKAMURA, Motozo YAMASHITA, Shinya MURAKAMI.
- Organizer
  2016 IADR GENERAL SESSION
- Place of Presentation
  Seoul, Korea
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02579
[Presentation] Loeys-Dietz症候群モデルマウスの作製と解析2015
- Author(s)
  津島　賢一朗，山田　聡，粟田　敏仁，山羽　聡子，阪下　裕美，竹立　匡秀，北垣　次郎太，山下　元三，柳田　学，野崎　剛徳，北村　正博，齋藤　正寛，村上　伸也
- Organizer
  第58回春季日本歯周病学会学術大会
- Place of Presentation
  幕張メッセ（千葉）
- Year and Date
  2015-05-15
- Data Source
  KAKENHI-PROJECT-15H02579
[Presentation] Cigarette smoke condensate and nicotine exacerbate periodontal tissue destruction in periodontitis-model mouse2015
- Author(s)
  Manabu Yanagita, Mikiko Kubota , Kenta Mori, Shiori Hasegawa, Satoko Yamaba,　Motozo Yamashita, Satoru Yamada, Masahiro Kitamura, and Shinya Murakami
- Organizer
  2015 IADR/AADR/CADR General Session & Exhibition
- Place of Presentation
  Hynes Convention Center（USA, Mass., Boston)
- Year and Date
  2015-03-12
- Data Source
  KAKENHI-PROJECT-25670884
[Presentation] ゲノムワイドアプローチによる日本人侵襲性歯周炎の疾患関連遺伝子探索2015
- Author(s)
  宮内静香、北垣次郎太、山下元三、山田聡、北村正博、村上伸也
- Organizer
  第142回日本歯科保存学会2015年度春季学術大会
- Place of Presentation
  北九州国際会議場（小倉）
- Year and Date
  2015-06-26
- Data Source
  KAKENHI-PROJECT-15K11385
[Presentation] ゲノムワイドアプローチによる日本人侵襲性歯周炎の疾患関連遺伝子探索2015
- Author(s)
  宮内静香、北垣次郎太、山下元三、山田　聡、北村正博、村上伸也
- Organizer
  第142回日本歯科保存学会2015年度春季学術大会
- Place of Presentation
  北九州国際会議場（小倉）
- Year and Date
  2015-06-26
- Data Source
  KAKENHI-PROJECT-15H02579
[Presentation] ゲノムワイドアプローチによる日本人侵襲性歯周炎の疾患関連遺伝子探索2015
- Author(s)
  北垣次郎太、宮内静香、今井敦子、朝野仁裕、河合伸治、道上郁美、山下元三、山田聡、北村正博、村上伸也
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド（兵庫）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15H02579
[Presentation] Cigarette smoke condensate and nicotine exacerbate periodontal tissue destruction in periodontitis-model mouse2015
- Author(s)
  M Yanagita, M Kubota , K Mori, S Hasegawa, S Yamaba,　Motozo Yamashita, S Yamada, M Kitamura, S Murakami
- Organizer
  2015 IADR/AADR/CADR General Session & Exhibition
- Place of Presentation
  Boston, USA
- Year and Date
  2015-03-12
- Data Source
  KAKENHI-PROJECT-24390466
[Presentation] 日本人侵襲性歯周炎患者のヒトエクソーム解読と遺伝子多型解析2015
- Author(s)
  北垣次郎太、宮内静香、山下元三、山田聡、北村正博、村上伸也
- Organizer
  第143回秋季保存学術大会
- Place of Presentation
  文京シビックホール（東京）
- Year and Date
  2015-11-13
- Data Source
  KAKENHI-PROJECT-15H02579
[Presentation] 日本人侵襲性歯周炎患者のヒトエクソーム解読と遺伝子多型解析2015
- Author(s)
  北垣次郎太、宮内静香、山下元三、山田聡、北村正博、村上伸也
- Organizer
  第143回秋季保存学術大会
- Place of Presentation
  文京シビックホール（東京）
- Year and Date
  2015-11-13
- Data Source
  KAKENHI-PROJECT-15K11385
[Presentation] Pathomolecular relationship between Loeys-Dietz syndrome and aggressive periodontitis2015
- Author(s)
  Kenichiro TSUSHIMA, Satoru YAMADA, Toshihito AWATA, Satoko YAMABA, Hiromi SAKASHITA, Masahide TAKEDACHI, Jirouta KITAGAKI, Motozo YAMASHITA, Manabu YANAGITA, Takenori NOZAKI, Masahiro KITAMURA, Shinya MURAKAMI
- Organizer
  第63回国際歯科研究学会学術大会
- Place of Presentation
  福岡国際会議場（福岡）
- Year and Date
  2015-10-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02579
[Presentation] ゲノムワイドアプローチによる日本人侵襲性歯周炎の疾患関連遺伝子探索2015
- Author(s)
  北垣次郎太、宮内静香、今井敦子、朝野仁裕、河合伸治、道上郁美、山下元三、山田聡、北村正博、村上伸也
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド（兵庫）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K11385
[Presentation] 歯肉上皮細胞における TLR3 を介した TLR2 発現上昇の機構2015
- Author(s)
  森健太、柳田学、久保田実木子、長谷川詩織、山下元三、山田聡、北村正博、村上伸也
- Organizer
  第143回秋季日本歯科保存学会
- Place of Presentation
  文京シビックホール、東京
- Year and Date
  2015-11-13
- Data Source
  KAKENHI-PROJECT-26463133
[Presentation] 70歳を対象にした歯周病罹患実態の調査2014
- Author(s)
  松井美樹、北村正博、柏木陽一郎、池永有里、川口佳保里、西原千尋、藤原健太、森永泰樹、鈴木美麻、平井麻絵、北垣次郎太、竹立匡秀、柳田　学、山下元三、野崎剛徳、山田　聡、池邉一典、前田芳信、村上伸也
- Organizer
  第57回秋季日本歯周病学会学術大会
- Place of Presentation
  神戸国際会議場（神戸）
- Year and Date
  2014-10-19
- Data Source
  KAKENHI-PROJECT-23249086
[Presentation] 高齢双生児者における歯周病細菌抗体価と遺伝要因の解析2014
- Author(s)
  東山弥生、山下元三、三木康史、池上久仁子、津島賢一朗、川口佳保里、久保田実木子、小河　大、西原千尋、藤原健太、池永友里、森永泰樹、北垣次郎太、柳田　学、野崎剛徳、久留島悠子、榎木香織、松田謙一、池邉一典、北村正博、前田芳信、村上伸也
- Organizer
  第141回秋季日本歯科保存学会
- Place of Presentation
  山形テルサ（山形）
- Year and Date
  2014-10-31
- Data Source
  KAKENHI-PROJECT-23249086
[Presentation] Analysis of cellular senescence in aged human periodontal ligament cells2014
- Author(s)
  K Ikegami, M Yamashita, T Nakamura, M Kubota, K Mori, M Yanagita, M Kitamura S Murakami
- Organizer
  AAP 100th Anniversary Annual Meeting
- Place of Presentation
  San Francisco, USA
- Year and Date
  2014-09-20
- Data Source
  KAKENHI-PROJECT-24390466
[Presentation] ヒト歯根膜細胞のストレス応答におけるオートファジーの関与2014
- Author(s)
  中村友美、山下元三、池上久仁子、柳田　学、竹立匡秀、山田　聡、北村正博、村上伸也
- Organizer
  第140回春季日本歯科保存学会
- Place of Presentation
  滋賀県立芸術劇場（滋賀県、大津市）
- Year and Date
  2014-06-20
- Data Source
  KAKENHI-PROJECT-25670884
[Presentation] Identification of the genetic polymorphism on aggressive periodontitis in Japanese2014
- Author(s)
  J Kitagaki, S Miyauchi, M Yamashita, S Yamada, M Kitamura, S Murakami
- Organizer
  第62回国際歯科研究学会日本部会（JADR）学術大会
- Place of Presentation
  KKRホテル（大阪）
- Year and Date
  2014-12-04
- Data Source
  KAKENHI-PROJECT-23249086
[Presentation] 老化ヒト歯根膜細胞におけるmicroRNA発現の網羅解析2014
- Author(s)
  池上久仁子、山下元三、中村友美、東山弥生、阪下裕美、山本智美、柳田　学、野崎剛徳、山田　聡、北村正博、村上伸也
- Organizer
  第140回春季日本歯科保存学会
- Place of Presentation
  滋賀県立芸術劇場（滋賀県、大津市）
- Year and Date
  2014-06-20
- Data Source
  KAKENHI-PROJECT-25670884
[Presentation] 初期固定力の不十分なインプラントに対する FGF-2 の安定性獲得促進効果2014
- Author(s)
  野崎剛徳, 田中利江, 沢田啓吾, 小笹匡雄, 三木康史, 池上久仁子, 阪下裕美, 山本智美, 宮内静香, 北垣次郎太, 山下元三, 山田聡, 白石紀子, 安齋純
- Organizer
  第57回秋季日本歯周病学会学術大会
- Place of Presentation
  神戸国際展示場
- Year and Date
  2014-10-19
- Data Source
  KAKENHI-PROJECT-24592956
[Presentation] AUTOPHAGY REGULATES EXTRACELLULAR MATRIX PRODUCTION BY HUMAN PERIODONTAL LIGAMENT CELLS2014
- Author(s)
  M Yamashita, T Nakamura, K Ikegami, S Yamaba, M Kubota, K Mori, M Yanagita, T Nozaki, M Kitamura, S Murakami
- Organizer
  AAP 100th Anniversary Annual Meeting
- Place of Presentation
  San Francisco, USA
- Year and Date
  2014-09-20
- Data Source
  KAKENHI-PROJECT-24390466
[Presentation] FGF-2存在下で分化した単球はM2マクロファージに類似した形質を有する2014
- Author(s)
  長谷川詩織、柳田学、久保田実木子、森健太、山下元三、山田聡、北村正博、村上伸也
- Organizer
  第141回秋季日本歯科保存学会
- Place of Presentation
  山形
- Year and Date
  2014-10-31
- Data Source
  KAKENHI-PROJECT-26463133
[Presentation] エクソーム解析を用いた侵襲性歯周炎の原因遺伝子の探索2014
- Author(s)
  北垣次郎太、宮内静香、今井敦子、朝野仁裕、橋野恵衣、河合伸治、道上郁美、山下元三、村上伸也
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川）
- Year and Date
  2014-11-25
- Data Source
  KAKENHI-PROJECT-23249086
[Presentation] ヒト歯根膜細胞のSASP（Senescence-associated secretory phenotype）の解析2013
- Author(s)
  山下元三、池上久仁子、山田聡、北村正博、村上伸也
- Organizer
  第36回　日本分子生物学会年会
- Place of Presentation
  兵庫（神戸国際会議場）
- Data Source
  KAKENHI-PROJECT-24390466
[Presentation] 高齢双生児の歯周病における遺伝因子と環境因子の関与2013
- Author(s)
  三木康史、山下元三、北垣次郎太、池上久仁子、久保田実木子、粟田敏仁、梶川哲宏、竹立匡秀、柳田学、野崎剛徳、山田聡、久留島悠子、松田謙一、池邉一典、北村正博、前田芳信、村上伸也、大阪ツインリサーチグループ
- Organizer
  第138回　日本歯科保存学会2013年度春季学術大会
- Place of Presentation
  福岡（福岡国際会議場）
- Data Source
  KAKENHI-PROJECT-23249086
[Presentation] 高齢双生児における口腔領域の類似度2013
- Author(s)
  久留島悠子、池邉一典、松田謙一、榎木香織、尾形宗士郎、山下元三、村上伸也、加藤憲司、早川和生、前田芳信、大阪ツインリサーチグループ
- Organizer
  日本双生児研究学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23249086
[Presentation] Analysis of SASP (senescence-associated secretory phenotype) in periodontal ligament2013
- Author(s)
  K Ikegami, M Yamashita, T Nakamura, M Yanagita, S Yamada, M Kitamura, S Murakami
- Organizer
  2nd Meeting of the International Association for Dental Research &; Asia Pacific Region
- Place of Presentation
  Bangkok, Thailand (Plaza Athenee,バンコク,タイ)
- Data Source
  KAKENHI-PROJECT-24390466
[Presentation] Genetic and Environmental Influences on Oral Condition among Elder Twins2013
- Author(s)
  Kurushima Y, Ikebe K, Matsuda K, Enoki K, Ogata S, Yamashita M, Murakami S, Kato K, Hayakawa K, Maeda Y, Osaka Twin Research Group
- Organizer
  91st General Session & Exhibition of the IADR
- Place of Presentation
  Seattle, USA
- Data Source
  KAKENHI-PROJECT-23249086
[Presentation] Effects of aging on ossification of periodontal ligament cells2012
- Author(s)
  Ikegami K, Yamashita M, Nakamura T, Kawahara T, Yanagita M, Yamada S, Kitamura M, Murakami S
- Organizer
  第60回国際歯科研究学会日本部会学術大会
- Place of Presentation
  新潟市
- Year and Date
  2012-12-14
- Data Source
  KAKENHI-PROJECT-23659975
[Presentation] Supportive periodontal therapyは歯の保存に有効である2012
- Author(s)
  山羽聡子、北村正博、松井美樹、山口泰司、東山弥生、松本航、久保田実木子、西村誠、山本温、吉岡恵理、竹立匡秀、北垣次郎太、柳田学、山下元三、野崎剛徳、山田聡、村上伸也
- Organizer
  第22回日本歯科医学会総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23249086
[Presentation] 歯根膜細胞においてFGF-2はWnt依存性にBMPシグナルを制御する2011
- Author(s)
  山下元三、河原貴展、橋本悠平、中村友美、梶川哲宏、森健太、前田憲一郎、北垣次郎太、柳田学、山田聡、北村正博、村上伸也
- Organizer
  日本歯科保存学会2011年度春季学術大会(第134回)
- Place of Presentation
  東京
- Year and Date
  2011-06-10
- Data Source
  KAKENHI-PROJECT-21689053
[Presentation] SIRT1による歯根膜細胞の石灰化制御2011
- Author(s)
  中村友美，山下元三，河原貴展，橋本悠平，梶川哲宏，森　健太，前田憲一郎，北垣次郎太，柳田　学，山田聡，北村正博，村上伸也
- Organizer
  日本歯科保存学会2011年度秋季学術大会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23659976
[Presentation] SIRT1による歯根膜細胞の石灰化制御2011
- Author(s)
  中村友美、山下元三、河原貴展、橋本悠平、梶川哲宏、森健太、前田憲一郎、北垣次郎太、柳田学、山田聡、北村正博、村上伸也
- Organizer
  第135回秋季日本歯科保存学会
- Place of Presentation
  大阪国際交流センター（　大阪府　）
- Data Source
  KAKENHI-PROJECT-23659975
[Presentation] Ossification of periodontal ligament cells induced by TGF-βtype I receptor inhibitor2011
- Author(s)
  T. KAWAHARA, M. YAMASHITA, and S. MURAKAMI
- Organizer
  Osaka International Symposium" Current Topics on Frontier Oral Science
- Place of Presentation
  Osaka
- Year and Date
  2011-11-24
- Data Source
  KAKENHI-PROJECT-21689053
[Presentation] TGF-βI型受容体阻害剤による歯根膜細胞の石灰化制御2011
- Author(s)
  T.KAWAHARA, M.YAMASHITA, S.MURAKAMI
- Organizer
  Osaka International Symposium "Current Topics on Frontier Oral Science
- Place of Presentation
  Osaka
- Year and Date
  2011-11-24
- Data Source
  KAKENHI-PROJECT-21689053
[Presentation] Endogenous TGF-β downregulates mineralization of periodontal ligament cells in vitro2011
- Author(s)
  河原貴展、山下元三、橋本悠平,中村友美, 梶川哲宏, 前田憲一郎, 北垣次郎太, 山田聡, 北村正博, 村上伸也
- Organizer
  第32回日本炎症・再生医学会
- Place of Presentation
  京都
- Year and Date
  2011-06-03
- Data Source
  KAKENHI-PROJECT-21689053
[Presentation] SIRT1による歯根膜細胞の石灰化制御2011
- Author(s)
  中村友美, 山下元三, 河原貴展, 橋本悠平, 梶川哲宏, 森健太, 前田憲一郎, 北垣次郎太, 柳田学, 山田聡, 北村正博, 村上伸也
- Organizer
  日本歯科保存学会2011年度秋季学術大会(第135回)
- Place of Presentation
  大阪
- Year and Date
  2011-10-21
- Data Source
  KAKENHI-PROJECT-21689053
[Presentation] 歯根膜細胞におけるオートファジーの役割2011
- Author(s)
  中村友美，山下元三，河原貴展，橋本悠平, 梶川哲宏, 山田聡, 北垣次郎太, 前田憲一郎, 北村正博, 村上伸也
- Organizer
  第54回春季日本歯周病学会学術大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23659976
[Presentation] 歯根膜細胞においてFGF-2はWnt 依存性に BMP シグナルを制御する2011
- Author(s)
  山下元三
- Organizer
  日本歯科保存学会2011年度春季学術大会(第134回)
- Place of Presentation
  千葉(東京ベイ舞浜クラブリゾート)
- Year and Date
  2011-06-09
- Data Source
  KAKENHI-PROJECT-23390452
[Presentation] Dual mode of TGF-βfunction in periodontal ligamental cell calcification2011
- Author(s)
  T. KAWAHARA, M. YAMASHITA, T. Nakamura, T. KAJIKAWA, S. YAMADA, M. KITAMURA and S. MURAKAMI
- Organizer
  The 59th Annual Meeting of Japanese Association of Dental Research
- Place of Presentation
  Hiroshima
- Year and Date
  2011-10-09
- Data Source
  KAKENHI-PROJECT-21689053
[Presentation] 歯根膜細胞におけるオートファジーの役割2011
- Author(s)
  中村友美, 山下元三, 河原貴展, 橋本悠平, 梶川哲宏, 山田聡, 北垣次郎太, 前田憲一郎, 北村正博, 村上伸也
- Organizer
  第54回春季日本歯周病学会学術大会
- Place of Presentation
  福岡
- Year and Date
  2011-05-28
- Data Source
  KAKENHI-PROJECT-21689053
[Presentation] Endogenous TGF-βdownregulates mineralization of periodontal ligament cells in vitro2011
- Author(s)
  T. KAWAHARA, M. YAMASHITA, Y. HASHIMOTO, T. NAKAMURA, T. KAJIKAWA, S. YAMADA, M. KITAMURA, and S. MURAKAMI
- Organizer
  89th General Session & Exhibition of the IADR
- Place of Presentation
  San Diego, CA
- Year and Date
  2011-03-18
- Data Source
  KAKENHI-PROJECT-21689053
[Presentation] 歯根膜細胞においてFGF-2はWnt依存性にBMPシグナルを制御する2011
- Author(s)
  山下元三
- Organizer
  日本歯科保存学会2011年度春季学術大会(第134回)
- Place of Presentation
  東京ベイ舞浜クラブリゾート(千葉県)
- Year and Date
  2011-06-09
- Data Source
  KAKENHI-PROJECT-23390452
[Presentation] Post-transcriptional control of BMPsignaling by FGF-2 in periodontal ligament cells2011
- Author(s)
  Y. HASHIMOTO, M. YAMASHITA, T. KAWAHARA, T. NAKAMURA, T. KAJIKAWA, S. YAMADA, T. NOZAKI, M. KITAMURA, and S. MURAKAMI
- Organizer
  89th General Session & Exhibition of the IADR
- Place of Presentation
  San Diego, CA
- Year and Date
  2011-03-19
- Data Source
  KAKENHI-PROJECT-21689053
[Presentation] Endogenous TGF-βdownregulates mineralization of periodontal ligament cells in vitro2011
- Author(s)
  河原貴展、山下元三、橋本悠平, 中村友美, 梶川哲宏, 前田憲一郎, 北垣次郎太, 山田聡, 北村正博, 村上伸也
- Organizer
  第32回日本炎症・再生医学会
- Place of Presentation
  京都
- Year and Date
  2011-06-03
- Data Source
  KAKENHI-PROJECT-21689053
[Presentation] TGF-β signaling regulates mineralization of periodontal ligament cells2010
- Author(s)
  山下元三、河原貴展
- Organizer
  The 96th Annual Meeting of American Academy of Periodontology in collaboration with the Japanese Society of Periodontology
- Place of Presentation
  Honolulu, Hawaii
- Data Source
  KAKENHI-PROJECT-21689053
[Presentation] TGF-βsignaling regulates mineralization of periodontal ligament cells.2010
- Author(s)
  T. KAWAHARA, M. YAMASHITA, Y. HASHIMOTO, T. KAJIKAWA, S. YAMADA, M. KITAMURA, and S. MURAKAMI
- Organizer
  The 96th Annual Meeting of American Academy of Periodontology in collaboration with the Japanese Society of Periodontology
- Place of Presentation
  Honolulu, Hawai
- Year and Date
  2010-10-30
- Data Source
  KAKENHI-PROJECT-21689053
[Presentation] 歯根膜細胞においてFGF-2はMAPK依存性にBMPシグナルを抑制する2010
- Author(s)
  河原貴展、山下元三、橋本悠平、梶川哲宏、中村友美, 前田憲一郎、山田聡、北村正博、村上伸也
- Organizer
  第53回秋季日本歯周病学会学術大会
- Place of Presentation
  高松
- Year and Date
  2010-09-19
- Data Source
  KAKENHI-PROJECT-21689053
[Presentation] 歯根膜細胞においてFGF-2はMAPK依存性にBMPシグナルを抑制する2010
- Author(s)
  山下元三、河原貴展
- Organizer
  第53回日本歯周病学会秋季学術大会
- Place of Presentation
  高松
- Year and Date
  2010-09-19
- Data Source
  KAKENHI-PROJECT-21689053
[Presentation] FGF-2-MAPK signal pathway suppresses BMP signaling axis in periodontal ligament cells2010
- Author(s)
  T. Kawahara and M. YAMASHITA
- Organizer
  Osaka-Chulalongkorn-Mahidol Joint Symposium," Current topics on Oral Science"
- Place of Presentation
  Osaka
- Year and Date
  2010-11-26
- Data Source
  KAKENHI-PROJECT-21689053
[Presentation] FGF-2-MAPK signal pathway suppresses BMP signaling axis in periodontal ligament cells2010
- Author(s)
  山下元三、河原貴展
- Organizer
  Osaka-Chulalongkorn-Mahidol Joint Symposium
- Place of Presentation
  Osaka
- Year and Date
  2010-11-26
- Data Source
  KAKENHI-PROJECT-21689053
[Presentation] FGF-2はMAPK依存性にBMPによるSmad1リン酸化を抑制する2010
- Author(s)
  山下元三、河原貴展
- Organizer
  日本歯科保存学会2010年度春季学術大会(第132回)
- Place of Presentation
  熊本
- Year and Date
  2010-06-04
- Data Source
  KAKENHI-PROJECT-21689053
[Presentation] A negative feedback control of TGF-beta signaling by GSK3-mediated Smad3 linker phosphorylation at Ser2042009
- Author(s)
  山下元三
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-21689053
[Presentation] TGF-βI型受容体阻害剤による歯根膜細胞の石灰化制御2009
- Author(s)
  河原貴展、山下元三、梶川哲宏、橋本悠平、柳田学、山田聡、北村正博、村上伸也
- Organizer
  日本歯科保存学会2009年度秋季学術大会(第131回)
- Place of Presentation
  仙台
- Year and Date
  2009-10-29
- Data Source
  KAKENHI-PROJECT-21689053
[Presentation] FGF-2はMAPK依存性にBMPによるSmad1リン酸化を抑制する2009
- Author(s)
  河原貴展、山下元三、橋本悠平、梶川哲宏、前田憲一郎、北垣次郎太、山田聡、北村正博、村上伸也
- Organizer
  日本歯科保存学会2010年度春季学術大会(第132回)
- Place of Presentation
  熊本
- Year and Date
  2009-06-04
- Data Source
  KAKENHI-PROJECT-21689053
[Presentation] 老化歯根膜細胞による炎症性サイトカイン(SASP蛋白)の産生
- Author(s)
  池上久仁子、山下元三、柳田学、野崎剛徳、北村正博、村上伸也
- Organizer
  第36回日本炎症・再生医学会
- Place of Presentation
  虎ノ門ヒルズフォーラム（東京都、港区）
- Year and Date
  2015-07-22 – 2015-07-23
- Data Source
  KAKENHI-PROJECT-25670884
[Presentation] ヒト歯根膜細胞のSASP（Senescence-associated secretory phenotype）の解析
- Author(s)
  山下元三、池上久仁子、山田聡、北村正博、村上伸也
- Organizer
  第36回　日本分子生物学会年会
- Place of Presentation
  兵庫（神戸国際会議場）
- Invited
- Data Source
  KAKENHI-PROJECT-25670884
[Presentation] Analysis of SASP (senescence-associated secretory phenotype) in periodontal ligament
- Author(s)
  K Ikegami, M Yamashita, T Nakamura, M Yanagita, S Yamada, M Kitamura, S Murakami
- Organizer
  2nd Meeting of the International Association for Dental Research – Asia Pacific Region
- Place of Presentation
  Bangkok, Thailand (Plaza Athenee,バンコク,タイ)
- Invited
- Data Source
  KAKENHI-PROJECT-25670884
[Presentation] ヒト歯根膜細胞の老化により誘導されるSASPの解析
- Author(s)
  池上久仁子、山下元三、山羽聡子、中村友美、森健太、粟田敏仁、柳田学、北村正博、村上伸也
- Organizer
  第138回　日本歯科保存学会2013年度春季学術大会
- Place of Presentation
  福岡（福岡国際会議場）
- Invited
- Data Source
  KAKENHI-PROJECT-25670884
[Presentation] 老化歯根膜細胞における細胞外基質蛋白の発現変動
- Author(s)
  池上久仁子、山下元三、中村友美、柳田学、野崎剛徳、山田聡、北村正博、村上伸也
- Organizer
  第142回日本歯科保存学会2015年度春季大会
- Place of Presentation
  北九州国際会議場（福岡県、北九州市）
- Year and Date
  2015-06-25 – 2015-06-26
- Data Source
  KAKENHI-PROJECT-25670884

1. MURAKAMI Shinya (70239490)

# of Collaborated Projects: 13 results

# of Collaborated Products: 85 results
2. TAKEDACHI Masahide (60452447)

# of Collaborated Projects: 9 results

# of Collaborated Products: 12 results
3. YAMADA Satoru (40359849)

# of Collaborated Projects: 8 results

# of Collaborated Products: 48 results
4. Iwayama Tomoaki (80757865)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
5. 柏木陽一郎 (20598396)

# of Collaborated Projects: 6 results

# of Collaborated Products: 1 results
6. KITAGAKI Jirouta (90570292)

# of Collaborated Projects: 5 results

# of Collaborated Products: 45 results
7. KITAMURA Masahiro (10243247)

# of Collaborated Projects: 5 results

# of Collaborated Products: 48 results
8. NOZAKI Takenori (30263304)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
9. YANAGITA Manabu (80379081)

# of Collaborated Projects: 4 results

# of Collaborated Products: 14 results
10. IKEBE Kazunori (70273696)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
11. Ikegami Kuniko (80779116)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
12. 藤原千春 (00755358)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
13. 中村友美 (00807589)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
14. KAMIDE Kei (80393239)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. GONDO Yasuyuki (40250196)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. OZASA Masao (20624563)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. KOJIMA Yuko (90632141)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 森崎隆幸 (30174410)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 仲野和彦 (00379083)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 大川玲奈 (80437384)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 小椋俊彦 (70371028)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 山口佳則 (20386634)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 高阪貴之 (40755360)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 渡邉幹夫 (50294088)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 三木康史 (10598395)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 伊藤幸裕 (30636402)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. SAWADA Keigo

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. KINOSHITA Masaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 池邊一典

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results

Yamashita Motozo 山下 元三

YAMASHITA Motozo 山下 元三

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Regulation of Periodontal Tissue Aging - A Novel Strategy for Overcoming Periodontal Disease and Diabetes in the Elderly-Principal Investigator

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Creation of neo-epigenetic periodontal therapy targeting DNA twistPrincipal Investigator

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Extension of healthy longevity in body and periodontal tissue by NMN supplementation and senolytic treatmentPrincipal Investigator

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Development of time controlled therapy for aged periodontal tissue.Principal Investigator

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Yamashita Motozo 山下元三

YAMASHITA Motozo 山下元三