Hirata Shintaro 平田信太郎

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HIRATA Shintaro 平田信太郎

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Researcher Number	90525461
Other IDs
Affiliation (Current)	2025: 広島大学, 病院(医), 教授
Affiliation (based on the past Project Information) *help	2025: 広島大学, 病院(医), 教授 2021 – 2023: 広島大学, 病院(医), 教授 2020: 広島大学, 病院(医), 准教授 2016 – 2019: 広島大学, 病院(医), 講師 2013 – 2015: 産業医科大学, 大学病院, 講師 2009 – 2010: University of Occupational and Environmental Health, Japan, 医学部, 助教
Review Section/Research Field	Principal Investigator Laboratory medicine / Basic Section 54020:Connective tissue disease and allergy-related / Basic Section 52010:General internal medicine-related / 膠原病・アレルギー・感染症内科学 Except Principal Investigator Basic Section 08020:Social welfare-related / Basic Section 57030:Conservative dentistry-related
Keywords	Principal Investigator 関節リウマチ / バイオマーカー / メトトレキサート / 寛解 / 治癒 / 寛解休薬後再燃リスク / 臨床検査医学 / 予後予測 / 関節破壊 / 国際情報交換 … More / JAK (Janus kinase) / サイトカイン / CD4陽性T細胞 / CP690,550 / JAK(Janus kinase) / 全身性エリテマトーデス / 膠原病学 … More Except Principal Investigator ぶどう膜炎診療 / 地域連携 / Porphyromonas gingivalis / 歯周病 / 自己抗体 / ACPA / 関節リウマチ / 歯周炎 Less

Personalization and optimization of the initial treatment of rheumatoid arthritis through TDM of red blood cell MTX-PGPrincipal Investigator
- Principal Investigator
  
  平田信太郎
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Hiroshima University
眼炎症疾患の患者を中心とした診療連携におけるぶどう膜炎診療システムの有用性
- Principal Investigator
  
  原田陽介
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 08020:Social welfare-related
- Research Institution
  Hiroshima University
Elucidation of the mechanism of periodontal tissue destruction by ACPA derived from patients with rheumatoid arthritis and periodontopathogenic bacteria-related proteins
- Principal Investigator
  
  應原一久
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Hiroshima University
Development of predictive biomarkers that enable to "cure" rheumatoid arthritisPrincipal Investigator
- Principal Investigator
  
  Shintaro Hirata
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Hiroshima University
Investigation of revolutionary predictive biomarkers for structural damage and risk of flare after withdrawal of drugs due to remission in rheumatoid arthritisPrincipal Investigator
- Principal Investigator
  
  Hirata Shintaro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Hiroshima University
Investigation of novel multi-biomarker indices to predict for joint destruction in rheumatoid arthritisPrincipal Investigator
- Principal Investigator
  
  HIRATA Shintaro
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  University of Occupational and Environmental Health, Japan
Therapeutic strategy targeting Jak3 for systemic lupus erythematosusPrincipal Investigator
- Principal Investigator
  
  HIRATA Shintaro
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  University of Occupational and Environmental Health, Japan

All 2024 2021 2020 2019 2018 2017 2016 2015 2014 2013 2011 2010 2009 Other

All Journal Article Presentation Book

[Book] 実践リウマチ肺障害の診断-実際の症例に基づく胸部X線読影診断のポイント-2011
- Author(s)
  田中良哉、迎寛、齋藤和義、平田信太郎
- Total Pages
  127
- Publisher
  永井書店
- Data Source
  KAKENHI-PROJECT-21790953
[Journal Article] Periostin regulates integrin expression in gingival epithelial cells2024
- Author(s)
  Hirata Reika、Iwata Tomoyuki、Fujita Tsuyoshi、Nagahara Takayoshi、Matsuda Shinji、Sasaki Shinya、Taniguchi Yuri、Hamamoto Yuta、Ouhara Kazuhisa、Kudo Yasusei、Kurihara Hidemi、Mizuno Noriyoshi
- Journal Title
  
  Journal of Oral Biosciences
  
  Volume: 66 Issue: 1 Pages: 170-178
- DOI
  10.1016/j.job.2023.11.009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09983
[Journal Article] The Lipopolysaccharide Mutant Re-LPS Is a Useful Tool for Detecting LPS Contamination in Rheumatoid Synovial Cell Cultures2021
- Author(s)
  Kohno Hiroki、Ouhara Kazuhisa、Mokuda Sho、Tokunaga Tadahiro、Sugimoto Tomohiro、Watanabe Hirofumi、Ishitoku Michinori、Yoshida Yusuke、Mizuno Noriyoshi、Ozawa Tatsuhiko、Kawataka Masatoshi、Hirata Shintaro、Kishi Hiroyuki、Sugiyama Eiji
- Journal Title
  
  Pathobiology
  
  Volume: 89 Issue: 2 Pages: 92-100
- DOI
  10.1159/000520022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07940, KAKENHI-PROJECT-19K08908, KAKENHI-PROJECT-19K18499, KAKENHI-PROJECT-21H02962
[Journal Article] Tapering and discontinuation of oral glucocorticoids without deterioration of disease status in patients with rheumatoid arthritis under a stable treatment2021
- Author(s)
  Shintaro Hirata, Hiroki Kohno, Hirofumi Watanabe, Tadahiro Tokunaga, Yusuke Yoshida, Tomohiro Sugimoto, Sho Mokuda, Keisuke Oda, Takaki Nojima, Eiji Sugiyama
- Journal Title
  
  Modern Rheumatology
  
  Volume: ahead of print Issue: 4 Pages: 803-808
- DOI
  10.1080/14397595.2020.1864914
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K18499, KAKENHI-PROJECT-19K07940
[Journal Article] Serum CXCL10 levels are associated with better responses to abatacept treatment of rheumatoid arthritis.2020
- Author(s)
  Yukawa K, Mokuda S, Kohno H, Oi K, Kuranobu T, Tokunaga T, Yoshida Y, Yamana J, Iwahashi M, Hirata S, Yamana S, Sugiyama E.
- Journal Title
  
  Clin Exp Rheumatol
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07940
[Journal Article] Activin A Expressed in Rheumatoid Synovial Cells Downregulates TNFα-Induced CXCL10 Expression and Osteoclastogenesis2020
- Author(s)
  Kuranobu T, Mokuda S, Oi K, Tokunaga T, Yukawa K, Kohno H, Yoshida Y, Hirata S, Sugiyama E
- Journal Title
  
  Pathobiology
  
  Volume: - Issue: 3 Pages: 198-207
- DOI
  10.1159/000506260
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07940, KAKENHI-PROJECT-19K08908, KAKENHI-PROJECT-19K18499
[Journal Article] TGFβ1 Regulates Human RANKL-Induced Osteoclastogenesis via Suppression of NFATc1 Expression2020
- Author(s)
  Tokunaga T, Mokuda S, Kohno H, Yukawa K, Kuranobu T, Oi K, Yoshida Y, Hirata S, Sugiyama E
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 21 Issue: 3 Pages: 800-800
- DOI
  10.3390/ijms21030800
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07940, KAKENHI-PROJECT-19K08908, KAKENHI-PROJECT-19K18499
[Journal Article] Effect of Porphyromonas gingivalis infection on gut dysbiosis and resultant arthritis exacerbation in mouse model2020
- Author(s)
  Hamamoto Yuta、Ouhara Kazuhisa、Munenaga Syuichi、Shoji Mikio、Ozawa Tatsuhiko、Hisatsune Jyunzo、Kado Isamu、Kajiya Mikihito、Matsuda Shinji、Kawai Toshihisa、Mizuno Noriyoshi、Fujita Tsuyoshi、Hirata Shintaro、Tanimoto Kotaro、Nakayama Koji、Kishi Hiroyuki、Sugiyama Eiji、Kurihara Hidemi
- Journal Title
  
  Arthritis Research & Therapy
  
  Volume: 22 Issue: 1 Pages: 249-249
- DOI
  10.1186/s13075-020-02348-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07940, KAKENHI-PROJECT-19K08908, KAKENHI-PROJECT-19K10072, KAKENHI-PROJECT-20K09921, KAKENHI-PROJECT-20K18537, KAKENHI-PLANNED-16H06499, KAKENHI-PROJECT-18H02689, KAKENHI-PROJECT-18K09599, KAKENHI-PROJECT-19K18999, KAKENHI-PROJECT-19K24073
[Journal Article] Tumour necrosis factor alpha promotes secretion of 14-3-3η by inducing necroptosis in macrophages2020
- Author(s)
  Trimova G, Yamagata K, Iwata S, Hirata S, Zhang T, Uemura F, Satoh M, Biln N, Nakayamada S, Maksymowych WP, Tanaka Y
- Journal Title
  
  Arthritis Res Ther
  
  Volume: 22 Issue: 1 Pages: 24-24
- DOI
  10.1186/s13075-020-2110-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07940, KAKENHI-PROJECT-19K08925, KAKENHI-PROJECT-19K08617
[Journal Article] Tumour necrosis factor α augments the inhibitory effects of CTLA‐4‐Ig on osteoclast generation from human monocytes via induction of CD80 expression2019
- Author(s)
  Oi K, Tokunaga T, Kuranobu T, Yukawa K, Kohno H, Yoshida Y, Mokuda S, Hirata S, Sugiyama E
- Journal Title
  
  Clin Exp Immunol
  
  Volume: 196 Issue: 3 Pages: 392-402
- DOI
  10.1111/cei.13271
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07940
[Journal Article] Increased remodelling of interstitial collagens and basement membrane is suppressed by treatment in patients with rheumatoid arthritis: serological evaluation of a one-year prospective study of 149 Japanese patients.2018
- Author(s)
  Gudmann NS, Hirata S, Karsdal MA, Kubo S, Bay-Jensen AC, Tanaka Y.
- Journal Title
  
  Clin Exp Rheumatol.
  
  Volume: 36 Pages: 462-470
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08956
[Journal Article] SLEバイオマーカーとしての可溶性VCAM-12017
- Author(s)
  平田信太郎
- Journal Title
  
  リウマチ科
  
  Volume: 57 Pages: 317-320
- Data Source
  KAKENHI-PROJECT-16K08956
[Journal Article] Association of the multi-biomarker disease activity score with joint destruction in patients with rheumatoid arthritis receiving tumor necrosis factor-alpha inhibitor treatment in clinical practice.2016
- Author(s)
  Hirata S, Li W, Kubo S, Fukuyo S, Mizuno Y, Hanami K, Sawamukai N, Yamaoka K, Saito K, Defranoux NA, Tanaka Y.
- Journal Title
  
  Mod Rheumatol.
  
  Volume: Epub Mar 30
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460713
[Journal Article] Association of the multi-biomarker disease activity score with joint destruction in patients with rheumatoid arthritis receiving tumor necrosis factor-alpha inhibitor treatment in clinical practice.2016
- Author(s)
  Hirata S, Li W, Kubo S, Fukuyo S, Mizuno Y, Hanami K, Sawamukai N, Yamaoka K, Saito K, Defranoux NA, Tanaka Y.
- Journal Title
  
  Mod Rheumatol
  
  Volume: 26 Issue: 6 Pages: 850-856
- DOI
  10.3109/14397595.2016.1153449
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08956, KAKENHI-PROJECT-16K09915
[Journal Article] Serum 14-3-3η level is associated with severity and clinical outcomes of rheumatoid arthritis, and its pretreatment level is predictive of DAS28 remission with tocilizumab.2015
- Author(s)
  Hirata S, Marotta A, Gui Y, Hanami K, Tanaka Y.
- Journal Title
  
  Arthritis Res Ther.
  
  Volume: 17 Issue: 1 Pages: 280-280
- DOI
  10.1186/s13075-015-0799-7
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460713, KAKENHI-PROJECT-26860764
[Journal Article] A multi-biomarker disease activity score tracks clinical response consistently in patients with rheumatoid arthritis treated with different anti-tumor necrosis factor therapies: A retrospective observational study.2015
- Author(s)
  Hirata S, Li W, Defranoux N, Cavet G, Bolce R, Yamaoka K, Saito K, Tanaka Y.
- Journal Title
  
  Mod Rheumatol.
  
  Volume: 25 Issue: 3 Pages: 344-9
- DOI
  10.3109/14397595.2014.958893
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460713
[Journal Article] Combination therapy for early rheumatoid arthritis: a treatment holiday perspective.2015
- Author(s)
  Hirata S, Tanaka Y.
- Journal Title
  
  Expert Rev Clin Pharmacol.
  
  Volume: 8 Issue: 1 Pages: 115-22
- DOI
  10.1586/17512433.2015.984689
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460713
[Journal Article] Discontinuation of adalimumab after achieving remission in patients with established rheumatoid arthritis: 1-year outcome of the HONOR study.2014
- Author(s)
  Tanaka Y, Hirata S, Kubo S, Fukuyo S, Hanami K, Sawamukai N, Nakano K, Nakayamada S, Yamaoka K, Sawamura F, Saito K.
- Journal Title
  
  Ann Rheum Dis
  
  Volume: in press Issue: 2 Pages: 389-95
- DOI
  10.1136/annrheumdis-2013-204016
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460713, KAKENHI-PROJECT-26860764
[Journal Article] Abatacept inhibits radiographic progression in patients with rheumatoid arthritis: a retrospective analysis of 6 months of abatacept treatment in routine clinical practice. The ALTAIR study.2014
- Author(s)
  Kubo S, Saito K, Hirata S, Fukuyo S, Yamaoka K, Sawamukai N, Nawata M, Iwata S, Mizuno Y, Tanaka Y.
- Journal Title
  
  Mod Rheumatol
  
  Volume: 24 Issue: 1 Pages: 42-51
- DOI
  10.3109/14397595.2013.854051
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460713
[Journal Article] Effects of tofacitinib on lymphocytes in rheumatoid arthritis: Relation to efficacy and infectious adverse events.2014
- Author(s)
  Sonomoto K, Yamaoka K, Kubo S, Hirata S, Fukuyo S, Maeshima K, Suzuki K, Saito K, Tanaka Y.
- Journal Title
  
  Rheumatology (Oxford).
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460713
[Journal Article] A multi-biomarker disease activity score tracks clinical response consistently in patients with rheumatoid arthritis treated with different anti-tumor necrosis factor therapies: A retrospective observational study.2014
- Author(s)
  Hirata S, Li W, Defranoux N, Cavet G, Bolce R, Yamaoka K, Saito K, Tanaka Y.
- Journal Title
  
  Mod Rheumatol.
  
  Volume: Oct 8: 1-6. Epub
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25460713
[Journal Article] Primary and secondary surveys on epidemiology of Sjören's syndrome in Japan.2014
- Author(s)
  Tsuboi H, Asashima H, Takai C, Hagiwara S, Hagiya C, Yokosawa M, Hirota T, Umehara H, Kawakami A, Nakamura H, Sano H, Tsubota K, Ogawa Y, Takamura E, Saito I, Inoue H, Nakamura S, Moriyama M, Takeuchi T, Tanaka Y, Hirata S, Mimori T, Yoshifuji H, Ohta A, Matsumoto I, Sumida T.
- Journal Title
  
  Mod Rheumatol
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460713
[Journal Article] Is It Possible to Withdraw Biologics From Therapy in Rheumatoid Arthritis?2014
- Author(s)
  TanakaY, Hirata S.
- Journal Title
  
  Clin Ther
  
  Volume: in press Issue: 12 Pages: 2028-2035
- DOI
  10.1016/j.clinthera.2013.10.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460713
[Journal Article] Efficacy and safety of reducing duration of infliximab infusion.2014
- Author(s)
  Fukuyo S, Saito K, Yamaoka K, Sawamukai N, Hirata S, Nawata M, Iwata S, Tanaka Y.
- Journal Title
  
  Mod Rheumatol
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460713
[Journal Article] Discontinuation of adalimumab after attaining disease activity score 28-erythrocyte sedimentation rate remission in patients with rheumatoid arthritis (HONOR study): an observational study.2013
- Author(s)
  Hirata S, Saito K, Kubo S, Fukuyo S, Mizuno Y, Iwata S, Nawata M, Sawamukai N, Nakano K, Yamaoka K, Tanaka Y.
- Journal Title
  
  Arthritis Res Ther
  
  Volume: 15 Issue: 5
- DOI
  10.1186/ar4315
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460713
[Journal Article] A multi-biomarker score measures rheumatoid arthritis disease activity in the BeSt study.2013
- Author(s)
  Hirata S, Dirven L, Shen Y, Centola M, Cavet G, Lems WF, Tanaka Y, Huizinga TW, Allaart CF.
- Journal Title
  
  Rheumatology (Oxford)
  
  Volume: 52 Issue: 7 Pages: 1202-7
- DOI
  10.1093/rheumatology/kes362
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460713
[Journal Article] Discontinuation of biologics in patients with rheumatoid arthritis.2013
- Author(s)
  Tanaka Y, Hirata S, Saleem B, Emery P.
- Journal Title
  
  Clin Exp Rheumatol
  
  Volume: 31
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460713
[Presentation] リウマチ滑膜細胞のTLR4活性化研究におけるLPSのコンタミネーションの検出に、変異型LPS・Re-LPSは有用である2021
- Author(s)
  24.河野紘輝, 應原一久, 德永忠浩, 茂久田翔, 水野智仁, 小澤龍彦, 川高正聖, 平田信太郎, 岸　裕幸, 杉山英二
- Organizer
  第36回日本臨床リウマチ学会
- Data Source
  KAKENHI-PROJECT-19K07940
[Presentation] 無治療の関節リウマチの血清反応陽性例、陰性例における血清バイオマーカー値の比較検討2021
- Author(s)
  河野紘輝, 荒木慧, 石德理訓, 渡辺裕文, 茂久田翔, 平田信太郎, 杉山英二
- Organizer
  第36回日本臨床リウマチ学会
- Data Source
  KAKENHI-PROJECT-19K07940
[Presentation] 関節リウマチ滑膜細胞におけるシトルリン化フィブリノーゲンのCXCL10誘導作用とその機序の検討2020
- Author(s)
  河野紘輝, 應原一久, 大本卓司, 渡辺裕文, 湯川和俊, 徳永忠浩, 倉信達臣, 大井勝博, 杉本智裕, 吉田雄介, 茂久田翔, 小田啓介, 野島崇樹, 平田信太郎, 杉山英二
- Organizer
  第64回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-19K07940
[Presentation] Tapering and Discontinuing Prednisolone Without Deteriorated Disease Control by Optimizing Methotrexate in Patients with Rheumatoid Arthritis Under Stable Treatment - 2-year Results in the Real-world Clinical Practice -2019
- Author(s)
  Hirata S, Omoto T, Kohno H, Watanabe H, Yukawa K, Tokunaga T, Kuranobu T, Oi K, Yoshida Y, Sugimoto T, Mokuda S, Oda K, Nojima T, Sugiyama E
- Organizer
  2019 ACR/ARP Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07940
[Presentation] Practical Optimization of Methotrexate Dose Improves Disease Control of Rheumatoid Arthritis Despite Reduction or Discontinuation of Oral Glucocorticoids.2018
- Author(s)
  Shintaro Hirata, Kei Araki, Hiroki Kohno, Kazutoshi Yukawa, Tadahiro Tokunaga, Tatsuomi Kuranobu, Katsuhiro Oi, Yusuke Yoshida, Tomohiro Sugimoto, Keisuke Oda, Takaki Nojima, Eiji Sugiyama
- Organizer
  ACR/ARHP2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08956
[Presentation] 疾患活動性評価の正確化（Multi-biomarker disease activity（MBDA）score による活動性評価）2018
- Author(s)
  平田信太郎
- Organizer
  第33回日本臨床リウマチ学会
- Invited
- Data Source
  KAKENHI-PROJECT-16K08956
[Presentation] OPTIMISATION OF METHOTREXATE DOSE INDUCED SUCCESSFUL REDUCTION OF GLUCOCORTICOIDS WITHOUT IMPAIRED DISEASE CONTROL IN PATIENTS WITH RHEUMATOID ARTHRITIS.2018
- Author(s)
  251.S. Hirata, T. Kondo, K. Yukawa, T. Tokunaga, T. Kuranobu, K. Oi, Y. Yoshida, M. Funaki, K. Oda, T. Nojima, E. Sugiyama
- Organizer
  EULAR2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08956
[Presentation] 血清１４－３－３ηは関節リウマチ患者のトシリツマブ治療反応性を予測できる2017
- Author(s)
  田中良哉、平田信太郎、花見健太郎、Anthony　Marotta
- Organizer
  第61回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-16K08956
[Presentation] 血清１４－３－３ηによる関節リウマチ患者に於けるアダリムマブ(ADA)治療中止後の関節破壊進行と再燃の予測2017
- Author(s)
  田中良哉、平田信太郎、花見健太郎、Anthony　Marotta
- Organizer
  第61回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-16K08956
[Presentation] 当科開設以来の関節リウマチ（RA）に対する生物学的抗リウマチ薬（ｂDMARDｓ）選択と継続に関する検討．2017
- Author(s)
  平田信太郎、近藤拓馬、湯川和俊、德永忠浩、倉信達臣、大井勝博、吉田雄介、舟木将雅、小田啓介、野島崇樹、杉山英二
- Organizer
  第28回日本リウマチ学会中国・四国支部学術集会
- Data Source
  KAKENHI-PROJECT-16K08956
[Presentation] MULTICENTER 14-3-3ETA BIOMARKER REPRODUCIBILITY; THE JAPANESE EXPERIENCE.2017
- Author(s)
  S. Hirata, M. Kaneda, T. Isayama, Y. Gui, A. Marotta, W. P. Maksymowych, Y. Tanaka.
- Organizer
  EULAR 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08956
[Presentation] 14-3-3ETA PREDICTS JOINT DAMAGE PROGRESSION AND FLARING AFTER ADALIMUMAB DISCONTINUATION．2017
- Author(s)
  S. Hirata, A. Marotta, K. Hanami, Y. Tanaka.
- Organizer
  EULAR 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08956
[Presentation] 関節リウマチに伴う間質性肺疾患(RA-ILD)に対するタクロリムス(TAC)の有効性2017
- Author(s)
  平田信太郎、中野和久、久保智史、杉山英二、田中良哉
- Organizer
  第61回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-16K08956
[Presentation] Predicting Flare and Sustained Clinical Remission after Adalimumab Withdrawal Using the Multi-Biomarker Disease Activity (MBDA) Score2016
- Author(s)
  Shintaro Hirata, Xingbin Wang, CC Hwang, Ippei Miyagawa, Satoshi Kubo, Kazuhisa Nakano, Shingo Nakayamada, Kazuyoshi Saito, Nadine A. Defranoux, Yoshiya Tanaka
- Organizer
  ACR/ARHP 2016
- Place of Presentation
  Washington DC, USA
- Year and Date
  2016-11-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08956
[Presentation] Lower Baseline 14-3-3η Levels Are Associated with Better Patient Reported Outcomes in Tocilizumab Treated Patients2016
- Author(s)
  Shintaro Hirata, Anthony Marotta, Kentaro Hanami, Yoshiya Tanaka
- Organizer
  ACR/ARHP 2016
- Place of Presentation
  Washington DC, USA
- Year and Date
  2016-11-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08956
[Presentation] PREDICTIVE VALUE OF THE MULTI-BIOMARKER DISEASE ACTIVITY (MBDA) SCORE FOR FLARE AND SUSTAINED REMISSION IN THE HONOR STUDY2016
- Author(s)
  S. Hirata, S. Tang, C.C. Hwang, I. Miyagawa, S. Kubo, K. Nakano, S. Nakayamada, K. Saito, N.A. Defranoux, Y. Tanaka
- Organizer
  EULAR2016
- Place of Presentation
  London, UK
- Year and Date
  2016-06-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08956
[Presentation] BASELINE SERUM 14-3-3 ETA INDEPENDENTLY PREDICTS CLINICALLY IMPORTANT IMPROVEMENTS IN HAQ-DI IN PATIENTS WITH RHEUMATOID ARTHRITIS TREATED WITH TOCILIZUMAB2016
- Author(s)
  S. Hirata, K. Hanami, A. Marotta, Y. Tanaka
- Organizer
  EULAR2016
- Place of Presentation
  London, UK
- Year and Date
  2016-06-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08956
[Presentation] ANTI-JAK IS ANTI-FIBROTIC IN PATIENTS WITH RHEUMATOID ARTHRITIS2016
- Author(s)
  S. Hirata, N.S. Gudmann, S. Kubo, M. Karsdal, A.C. Bay-Jensen, Y. Tanaka
- Organizer
  EULAR2016
- Place of Presentation
  London, UK
- Year and Date
  2016-06-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08956
[Presentation] 関節リウマチにおいてベースライン14-3-3η低値はtocilizumabによる1年後のDAS28-ESR寛解達成を予測する.2015
- Author(s)
  平田信太郎, 花見健太郎, 山形薫, 宮川一平, 久保智史, 岩田慈, 澤向範文, 中野和久, 中山田真吾, 齋藤和義, Anthony Marotta, 田中良哉
- Organizer
  第43回日本臨床免疫学会
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2015-10-22
- Data Source
  KAKENHI-PROJECT-25460713
[Presentation] Predictive value of the MBDA score and composite measures for sustained remission at 1 year after withdrawal of adalimumab in the HONOR study2015
- Author(s)
  Shintaro Hirata, Kentaro Hanami, Nadine Defranoux, Ippei Miyagawa, Satoshi Kubo, Shunsuke Fukuyo, Norifumi Sawamukai, Kazuhisa Nakano, Shingo Nakayamada, Kazuyoshi Saito, Yoshiya Tanaka
- Organizer
  第59回日本リウマチ学会総会・学術集会 (JCR2015)
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-04-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460713
[Presentation] Neo-epitopes of connective tissue turnover are biomarkers of disease activity and modulated in response to tofacitinib or tocilizumab in rheumatoid arthritis2015
- Author(s)
  Shintarto Hirata, Natasja S. Gudmann, Morten Karsdal, Anne C. Bay-Jensen, Yoshiya Tanaka
- Organizer
  EULAR2015
- Place of Presentation
  Rome, Italy
- Year and Date
  2015-06-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460713
[Presentation] The relevance of serum 14-3-3η levels to clinical and radiographic outcomes in patients with rheumatoid arthritis2015
- Author(s)
  Shintaro Hirata, Kentaro Hanami, Kaoru Yamagata, Ippei Miyagawa, Satoshi Kubo, Shunsuke Fukuyo, Norifumi Sawamukai, Kazuhisa Nakano, Shingo Nakayamada, Kazuyoshi Saito, Anthony Marotta, Yoshiya Tanaka
- Organizer
  第59回日本リウマチ学会総会・学術集会 (JCR2015)
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-04-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460713
[Presentation] JAK Inhibition Significantly Reduced Fibrogenesis in Rheumatoid Arthritis Patients2015
- Author(s)
  Shintaro Hirata, Natasja Stæhr Gudman, Kentaro Hanami, Satoshi Kubo, Anne C. Bay-Jensen, Morten Asser Karsdal, Yoshiya Tanaka
- Organizer
  ACR2015
- Place of Presentation
  San Francisco, United States
- Year and Date
  2015-11-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460713
[Presentation] 14-3-3η Positive Status and Higher Titres Are Associated with More Severe RA2015
- Author(s)
  Shintaro Hirata, Kentaro Hanami, Anthony Marotta, Yoshiya Tanaka
- Organizer
  ACR2015
- Place of Presentation
  San Francisco, United States
- Year and Date
  2015-11-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460713
[Presentation] Multi-biomarker disease activity (MBDA)スコアは関節リウマチにおける最も鋭敏に構造的寛解を予測、反映する疾患活動性マーカーである2013
- Author(s)
  平田信太郎, 齋藤和義, 久保智史, 福與俊介, 水野泰志, Wanying Li, Douglas J. Haney, Nadine Defranoux, Rebecca Bolce, Guy Cavet, 園本格士朗,花見健太郎, 岩田慈, 名和田雅夫, 澤向範文, 中野和久, 中山田真吾, 山岡邦宏、田中良哉
- Organizer
  第57回日本リウマチ学会総会・学術集会（JCR2013)
- Place of Presentation
  京都（国立京都国際会館）
- Data Source
  KAKENHI-PROJECT-25460713
[Presentation] BEHAVIOR OF THE MULTI-BIOMARKER DISEASE ACTIVITY (VECTRA® DA ALGORITHM) SCORE AND COMPONENTS IN PATIENTS WITH RHEUMATOID ARTHRITIS TREATED WITH TOCILIZUMAB2013
- Author(s)
  K.Hanami, S.Hirata, H.Tasaka, W.Li, R.Bolce, E.H.Sasso, N.A.Defranoux, K.Yamaoka, K.Saito, Y.Tanaka
- Organizer
  EULAR2013
- Place of Presentation
  Madrid, Spain
- Data Source
  KAKENHI-PROJECT-25460713
[Presentation] A MULTI-BIOMARKER DISEASE ACTIVITY (VECTRA™ DA ALGORITHM) SCORE IS ASSOCIATED WITH RADIOGRAPHIC OUTCOMES IN RA PATIENTS TREATED WITH TNF INHIBITORS2013
- Author(s)
  S.Hirata, W.Li, N.A.Defranoux, R.Bolce, D.J.Haney, E.H.Sasso, S.Kubo, S.Fukuyo, Y.Mizuno, K.Yamaoka, K.Saito, Y.Tanaka
- Organizer
  EULAR2013
- Place of Presentation
  Madrid, Spain
- Data Source
  KAKENHI-PROJECT-25460713
[Presentation] 血清MMP-3はTNF阻害療法下の関節リウマチにおける関節裂隙狭小化スコアと相関性が高い2013
- Author(s)
  平田信太郎, 齋藤和義, 久保智史, 福與俊介, 水野泰志, 園本格士朗, 花見健太郎, 岩田慈, 名和田雅夫, 澤向範文, 中野和久, 中山田真吾, 山岡邦宏, 田中良哉
- Organizer
  第57回日本リウマチ学会総会・学術集会（JCR2013)
- Place of Presentation
  京都（国立京都国際会館）
- Data Source
  KAKENHI-PROJECT-25460713
[Presentation] A novel peripheral blood derived multi-biomarker disease activity (MBDA; Vectra™ DA Algorithm) score reflects clinical, functional, and radiographic outcomes in Japanese rheumatoid arthritis patients treated with TNF inhibitors2013
- Author(s)
  Shintaro Hirata, Wanying Li, Nadine A. Defranoux, Rebecca Bolce, Kentaro Hanami, Satoshi Kubo, Shunsuke Fukuyo, Yasushi Mizuno, Kunihiro Yamaoka, Kazuyoshi Saito, Yoshiya Tanaka
- Organizer
  EAGOR2013
- Place of Presentation
  Seoul, South Korea
- Data Source
  KAKENHI-PROJECT-25460713
[Presentation] REPEATED HIGH OR LOW MULTI-BIOMARKER DISEASE ACTIVITY (VECTRA® DA ALGORITHM) SCORES ASSOCIATED WITH RADIOGRAPHIC OUTCOMES IN PATIENTS WITH RA TREATED WITH TNF INHIBITORS2013
- Author(s)
  S.Hirata, W.Li, N.A.Defranoux, R.Bolce, E.H.Sasso, S.Kubo, S.Fukuyo, Y.Mizuno, K.Yamaoka, K.Saito, Y.Tanaka
- Organizer
  ACR2013
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-25460713
[Presentation] Analysis of clinical factors for achieving to EULAR low disease activity at 24 weeks with adalimumab in patients with RA.2010
- Author(s)
  Hirata S, Saito K, Tsujimura S, Nakano K, Yamaoka K, Tanaka
- Organizer
  International Workshop, The 54th Annual General Assembly and Scientific Meeting of The Japan College of Rheumagoloty
- Place of Presentation
  Kobe
- Year and Date
  2010-04-22
- Data Source
  KAKENHI-PROJECT-21790953
[Presentation] 膠原病合併IPに対するTacrolimusの有用性-Global composite measureによる評価の試み2010
- Author(s)
  平田信太郎, 齋藤和義, 久保智史, 辻村静代, 中野和久, 山岡邦宏, 田中良哉
- Organizer
  第54回日本リウマチ学会総会・学術集会
- Place of Presentation
  神戸
- Year and Date
  2010-04-24
- Data Source
  KAKENHI-PROJECT-21790953
[Presentation] サイトカインを標的とした病態制御の可能性関節リウマチにおける完全ヒトTNFα抗体Adalimumabの疾患活動性制御に関与する背景因子の検討2010
- Author(s)
  平田信太郎, 齋藤和義, 名和田雅夫, 辻村静代, 中野和久, 山岡邦宏, 田中良哉
- Organizer
  第31回日本炎症・再生医学会
- Place of Presentation
  東京
- Year and Date
  2010-08-05
- Data Source
  KAKENHI-PROJECT-21790953
[Presentation] Adalimumab(ADA)にて24週後に低疾患活動性(LDA)を達成する症例の背景因子の検討2010
- Author(s)
  平田信太郎, 齋藤和義, 辻村静代, 中野和久, 山岡邦宏, 田中良哉
- Organizer
  第54回日本リウマチ学会総会・学術集会
- Place of Presentation
  神戸
- Year and Date
  2010-04-24
- Data Source
  KAKENHI-PROJECT-21790953
[Presentation] 膠原病合併間質性肺炎に対するcomposite measureを用いたタクロリムスの有用性の検討2010
- Author(s)
  平田信太郎, 齋藤和義, 久保智史, 辻村静代, 中野和久, 山岡邦宏, 田中良哉
- Organizer
  第39回九州リウマチ学会
- Place of Presentation
  福岡
- Year and Date
  2010-03-06
- Data Source
  KAKENHI-PROJECT-21790953
[Presentation] 当科におけるアダリムマブ24週投与の解析アダリムマブの効果予測の可能性2009
- Author(s)
  平田信太郎, 齋藤和義, 久保智史, 宮川一平, 福與俊介, 花見健太郎, 湯川宗之助, 岩田慈, 名和田雅夫, 辻村静代, 中野和久, 山岡邦宏, 田中良哉
- Organizer
  第38回九州リウマチ学会
- Place of Presentation
  久留米
- Year and Date
  2009-09-05
- Data Source
  KAKENHI-PROJECT-21790953
[Presentation] 膠原病に伴う間質性肺炎に対するタクロリムスの有用性の検討2009
- Author(s)
  平田信太郎, 中野和久, 齋藤和義, 久保智史, 鈴木克典, 名和田雅夫, 澤向範文, 山岡邦宏, 田中良哉
- Organizer
  第53回日本リウマチ学会総会・学術集会
- Place of Presentation
  東京
- Year and Date
  2009-04-23
- Data Source
  KAKENHI-PROJECT-21790953
[Presentation] 関節リウマチに対するadalimumab(ADA)の早期有効性に関与する因子の検討2009
- Author(s)
  平田信太郎, 齋藤和義, 花見健太郎, 岩田慈, 名和田雅夫, 澤向範文, 中野和久, 山岡邦宏, 田中良哉
- Organizer
  第53回日本リウマチ学会総会・学術集会
- Place of Presentation
  東京
- Year and Date
  2009-04-24
- Data Source
  KAKENHI-PROJECT-21790953
[Presentation] TNF阻害療法下のRA患者におけるmulti-biomarker disease activity (MBDA)スコアと関節破壊進行に関する検討
- Author(s)
  平田信太郎, 齋藤和義, 久保智史, 福與俊介, 水野泰志, Wanying Li, Nadine A. Defranoux, Rebecca Bolce, Eric Sasso, 宮川一平,花見健太郎, 澤向範文, 中野和久, 中山田真吾, 山岡邦宏、田中良哉
- Organizer
  第58回日本リウマチ学会総会・学術集会 (JCR2014)
- Place of Presentation
  グランドプリンスホテル新高輪（東京都港区）
- Year and Date
  2014-04-24 – 2014-04-26
- Data Source
  KAKENHI-PROJECT-25460713
[Presentation] Neo-epitopes of connective tissue turnover are biomarkers of disease activity and modulated in response to tofacitinib or tocilizumab in rheumatoid arthritis
- Author(s)
  Shintarto Hirata, Natasja S. Gudmann, Morten Karsdal, Anne C. Bay-Jensen, Yoshiya Tanaka
- Organizer
  The Annual European Congress of Rheumatology EULAR 2015
- Place of Presentation
  Fiera Roma, Rome, Italy
- Year and Date
  2015-06-10 – 2015-06-13
- Data Source
  KAKENHI-PROJECT-25460713
[Presentation] 14-3-3eta Informs Joint Pathological Mechanisms of Treatment Response to Assist with T2T Strategies
- Author(s)
  Shintaro Hirata, Kentaro Hanami, Anthony Marotta, Yoshiya Tanaka
- Organizer
  2014 ACR/ARHP Annual Meeting
- Place of Presentation
  Boston Convention & Exhibition Center, Boston, Massachusetts, USA
- Year and Date
  2014-11-14 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-25460713

1. 吉田雄介 (60772051)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. 應原一久 (80550425)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. 庄子幹郎 (10336175)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 小澤龍彦 (10432105)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 原田陽介 (10464314)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 柳井亮二 (10346554)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 土居岳彦 (20572100)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 木内良明 (40214738)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 田中武志 (40325197)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 日山知奈 (10984437)

# of Collaborated Projects: 1 results

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11. 杉本智裕 (10848435)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 石徳理訓 (50924932)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 松尾裕彰 (60346385)

# of Collaborated Projects: 1 results

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14. 茂久田翔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hirata Shintaro 平田 信太郎

HIRATA Shintaro 平田 信太郎

Research Projects

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Personalization and optimization of the initial treatment of rheumatoid arthritis through TDM of red blood cell MTX-PGPrincipal Investigator

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眼炎症疾患の患者を中心とした診療連携におけるぶどう膜炎診療システムの有用性

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Elucidation of the mechanism of periodontal tissue destruction by ACPA derived from patients with rheumatoid arthritis and periodontopathogenic bacteria-related proteins

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Development of predictive biomarkers that enable to "cure" rheumatoid arthritisPrincipal Investigator

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Investigation of revolutionary predictive biomarkers for structural damage and risk of flare after withdrawal of drugs due to remission in rheumatoid arthritisPrincipal Investigator

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Investigation of novel multi-biomarker indices to predict for joint destruction in rheumatoid arthritisPrincipal Investigator

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Therapeutic strategy targeting Jak3 for systemic lupus erythematosusPrincipal Investigator

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[Book] 実践リウマチ肺障害の診断-実際の症例に基づく胸部X線読影診断のポイント-2011

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[Journal Article] Periostin regulates integrin expression in gingival epithelial cells2024

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[Journal Article] The Lipopolysaccharide Mutant Re-LPS Is a Useful Tool for Detecting LPS Contamination in Rheumatoid Synovial Cell Cultures2021

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[Journal Article] Tapering and discontinuation of oral glucocorticoids without deterioration of disease status in patients with rheumatoid arthritis under a stable treatment2021

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[Journal Article] Serum CXCL10 levels are associated with better responses to abatacept treatment of rheumatoid arthritis.2020

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[Journal Article] Activin A Expressed in Rheumatoid Synovial Cells Downregulates TNFα-Induced CXCL10 Expression and Osteoclastogenesis2020

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[Journal Article] TGFβ1 Regulates Human RANKL-Induced Osteoclastogenesis via Suppression of NFATc1 Expression2020

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Hirata Shintaro 平田信太郎

HIRATA Shintaro 平田信太郎