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Hirata Shintaro  平田 信太郎

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HIRATA Shintaro  平田 信太郎

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Researcher Number 90525461
Other IDs
Affiliation (Current) 2025: 広島大学, 病院(医), 教授
Affiliation (based on the past Project Information) *help 2025: 広島大学, 病院(医), 教授
2021 – 2023: 広島大学, 病院(医), 教授
2020: 広島大学, 病院(医), 准教授
2016 – 2019: 広島大学, 病院(医), 講師
2013 – 2015: 産業医科大学, 大学病院, 講師
2009 – 2010: University of Occupational and Environmental Health, Japan, 医学部, 助教
Review Section/Research Field
Principal Investigator
Laboratory medicine / Basic Section 54020:Connective tissue disease and allergy-related / Basic Section 52010:General internal medicine-related / 膠原病・アレルギー・感染症内科学
Except Principal Investigator
Basic Section 08020:Social welfare-related / Basic Section 57030:Conservative dentistry-related
Keywords
Principal Investigator
バイオマーカー / 関節リウマチ / 寛解 / 治癒 / 寛解休薬後再燃リスク / 臨床検査医学 / 予後予測 / 関節破壊 / 国際情報交換 / JAK (Janus kinase) … More / サイトカイン / CD4陽性T細胞 / CP690,550 / JAK(Janus kinase) / 全身性エリテマトーデス / 膠原病学 … More
Except Principal Investigator
ぶどう膜炎診療 / 地域連携 / Porphyromonas gingivalis / 歯周病 / 自己抗体 / ACPA / 関節リウマチ / 歯周炎 Less
  • Research Projects

    (7 results)
  • Research Products

    (68 results)
  • Co-Researchers

    (11 People)
  •  赤血球MTX-PGのTDMにより関節リウマチ初期治療の個別化・最適化を目指す研究Principal Investigator

    • Principal Investigator
      平田 信太郎
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54020:Connective tissue disease and allergy-related
    • Research Institution
      Hiroshima University
  •  眼炎症疾患の患者を中心とした診療連携におけるぶどう膜炎診療システムの有用性

    • Principal Investigator
      原田 陽介
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 08020:Social welfare-related
    • Research Institution
      Hiroshima University
  •  Elucidation of the mechanism of periodontal tissue destruction by ACPA derived from patients with rheumatoid arthritis and periodontopathogenic bacteria-related proteins

    • Principal Investigator
      應原 一久
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57030:Conservative dentistry-related
    • Research Institution
      Hiroshima University
  •  Development of predictive biomarkers that enable to "cure" rheumatoid arthritisPrincipal Investigator

    • Principal Investigator
      Shintaro Hirata
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Hiroshima University
  •  Investigation of revolutionary predictive biomarkers for structural damage and risk of flare after withdrawal of drugs due to remission in rheumatoid arthritisPrincipal Investigator

    • Principal Investigator
      Hirata Shintaro
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory medicine
    • Research Institution
      Hiroshima University
  •  Investigation of novel multi-biomarker indices to predict for joint destruction in rheumatoid arthritisPrincipal Investigator

    • Principal Investigator
      HIRATA Shintaro
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory medicine
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  Therapeutic strategy targeting Jak3 for systemic lupus erythematosusPrincipal Investigator

    • Principal Investigator
      HIRATA Shintaro
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      University of Occupational and Environmental Health, Japan

All 2024 2021 2020 2019 2018 2017 2016 2015 2014 2013 2011 2010 2009 Other

All Journal Article Presentation Book

  • [Book] 実践リウマチ肺障害の診断-実際の症例に基づく胸部X線読影診断のポイント-2011

    • Author(s)
      田中良哉、迎寛、齋藤和義、平田信太郎
    • Total Pages
      127
    • Publisher
      永井書店
    • Data Source
      KAKENHI-PROJECT-21790953
  • [Journal Article] Periostin regulates integrin expression in gingival epithelial cells2024

    • Author(s)
      Hirata Reika、Iwata Tomoyuki、Fujita Tsuyoshi、Nagahara Takayoshi、Matsuda Shinji、Sasaki Shinya、Taniguchi Yuri、Hamamoto Yuta、Ouhara Kazuhisa、Kudo Yasusei、Kurihara Hidemi、Mizuno Noriyoshi
    • Journal Title

      Journal of Oral Biosciences

      Volume: 66 Issue: 1 Pages: 170-178

    • DOI

      10.1016/j.job.2023.11.009

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K09983
  • [Journal Article] The Lipopolysaccharide Mutant Re-LPS Is a Useful Tool for Detecting LPS Contamination in Rheumatoid Synovial Cell Cultures2021

    • Author(s)
      Kohno Hiroki、Ouhara Kazuhisa、Mokuda Sho、Tokunaga Tadahiro、Sugimoto Tomohiro、Watanabe Hirofumi、Ishitoku Michinori、Yoshida Yusuke、Mizuno Noriyoshi、Ozawa Tatsuhiko、Kawataka Masatoshi、Hirata Shintaro、Kishi Hiroyuki、Sugiyama Eiji
    • Journal Title

      Pathobiology

      Volume: 89 Issue: 2 Pages: 92-100

    • DOI

      10.1159/000520022

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07940, KAKENHI-PROJECT-19K08908, KAKENHI-PROJECT-19K18499, KAKENHI-PROJECT-21H02962
  • [Journal Article] Tapering and discontinuation of oral glucocorticoids without deterioration of disease status in patients with rheumatoid arthritis under a stable treatment2021

    • Author(s)
      Shintaro Hirata, Hiroki Kohno, Hirofumi Watanabe, Tadahiro Tokunaga, Yusuke Yoshida, Tomohiro Sugimoto, Sho Mokuda, Keisuke Oda, Takaki Nojima, Eiji Sugiyama
    • Journal Title

      Modern Rheumatology

      Volume: ahead of print Issue: 4 Pages: 803-808

    • DOI

      10.1080/14397595.2020.1864914

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K18499, KAKENHI-PROJECT-19K07940
  • [Journal Article] Serum CXCL10 levels are associated with better responses to abatacept treatment of rheumatoid arthritis.2020

    • Author(s)
      Yukawa K, Mokuda S, Kohno H, Oi K, Kuranobu T, Tokunaga T, Yoshida Y, Yamana J, Iwahashi M, Hirata S, Yamana S, Sugiyama E.
    • Journal Title

      Clin Exp Rheumatol

      Volume: -

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07940
  • [Journal Article] Activin A Expressed in Rheumatoid Synovial Cells Downregulates TNFα-Induced CXCL10 Expression and Osteoclastogenesis2020

    • Author(s)
      Kuranobu T, Mokuda S, Oi K, Tokunaga T, Yukawa K, Kohno H, Yoshida Y, Hirata S, Sugiyama E
    • Journal Title

      Pathobiology

      Volume: - Issue: 3 Pages: 198-207

    • DOI

      10.1159/000506260

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07940, KAKENHI-PROJECT-19K08908, KAKENHI-PROJECT-19K18499
  • [Journal Article] TGFβ1 Regulates Human RANKL-Induced Osteoclastogenesis via Suppression of NFATc1 Expression2020

    • Author(s)
      Tokunaga T, Mokuda S, Kohno H, Yukawa K, Kuranobu T, Oi K, Yoshida Y, Hirata S, Sugiyama E
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 21 Issue: 3 Pages: 800-800

    • DOI

      10.3390/ijms21030800

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07940, KAKENHI-PROJECT-19K08908, KAKENHI-PROJECT-19K18499
  • [Journal Article] Effect of Porphyromonas gingivalis infection on gut dysbiosis and resultant arthritis exacerbation in mouse model2020

    • Author(s)
      Hamamoto Yuta、Ouhara Kazuhisa、Munenaga Syuichi、Shoji Mikio、Ozawa Tatsuhiko、Hisatsune Jyunzo、Kado Isamu、Kajiya Mikihito、Matsuda Shinji、Kawai Toshihisa、Mizuno Noriyoshi、Fujita Tsuyoshi、Hirata Shintaro、Tanimoto Kotaro、Nakayama Koji、Kishi Hiroyuki、Sugiyama Eiji、Kurihara Hidemi
    • Journal Title

      Arthritis Research & Therapy

      Volume: 22 Issue: 1 Pages: 249-249

    • DOI

      10.1186/s13075-020-02348-z

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07940, KAKENHI-PROJECT-19K08908, KAKENHI-PROJECT-19K10072, KAKENHI-PROJECT-20K09921, KAKENHI-PROJECT-20K18537, KAKENHI-PLANNED-16H06499, KAKENHI-PROJECT-18H02689, KAKENHI-PROJECT-18K09599, KAKENHI-PROJECT-19K18999, KAKENHI-PROJECT-19K24073
  • [Journal Article] Tumour necrosis factor alpha promotes secretion of 14-3-3η by inducing necroptosis in macrophages2020

    • Author(s)
      Trimova G, Yamagata K, Iwata S, Hirata S, Zhang T, Uemura F, Satoh M, Biln N, Nakayamada S, Maksymowych WP, Tanaka Y
    • Journal Title

      Arthritis Res Ther

      Volume: 22 Issue: 1 Pages: 24-24

    • DOI

      10.1186/s13075-020-2110-9

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07940, KAKENHI-PROJECT-19K08925, KAKENHI-PROJECT-19K08617
  • [Journal Article] Tumour necrosis factor α augments the inhibitory effects of CTLA‐4‐Ig on osteoclast generation from human monocytes via induction of CD80 expression2019

    • Author(s)
      Oi K, Tokunaga T, Kuranobu T, Yukawa K, Kohno H, Yoshida Y, Mokuda S, Hirata S, Sugiyama E
    • Journal Title

      Clin Exp Immunol

      Volume: 196 Issue: 3 Pages: 392-402

    • DOI

      10.1111/cei.13271

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07940
  • [Journal Article] Increased remodelling of interstitial collagens and basement membrane is suppressed by treatment in patients with rheumatoid arthritis: serological evaluation of a one-year prospective study of 149 Japanese patients.2018

    • Author(s)
      Gudmann NS, Hirata S, Karsdal MA, Kubo S, Bay-Jensen AC, Tanaka Y.
    • Journal Title

      Clin Exp Rheumatol.

      Volume: 36 Pages: 462-470

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08956
  • [Journal Article] SLEバイオマーカーとしての可溶性VCAM-12017

    • Author(s)
      平田 信太郎
    • Journal Title

      リウマチ科

      Volume: 57 Pages: 317-320

    • Data Source
      KAKENHI-PROJECT-16K08956
  • [Journal Article] Association of the multi-biomarker disease activity score with joint destruction in patients with rheumatoid arthritis receiving tumor necrosis factor-alpha inhibitor treatment in clinical practice.2016

    • Author(s)
      Hirata S, Li W, Kubo S, Fukuyo S, Mizuno Y, Hanami K, Sawamukai N, Yamaoka K, Saito K, Defranoux NA, Tanaka Y.
    • Journal Title

      Mod Rheumatol.

      Volume: Epub Mar 30

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25460713
  • [Journal Article] Association of the multi-biomarker disease activity score with joint destruction in patients with rheumatoid arthritis receiving tumor necrosis factor-alpha inhibitor treatment in clinical practice.2016

    • Author(s)
      Hirata S, Li W, Kubo S, Fukuyo S, Mizuno Y, Hanami K, Sawamukai N, Yamaoka K, Saito K, Defranoux NA, Tanaka Y.
    • Journal Title

      Mod Rheumatol

      Volume: 26 Issue: 6 Pages: 850-856

    • DOI

      10.3109/14397595.2016.1153449

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08956, KAKENHI-PROJECT-16K09915
  • [Journal Article] Serum 14-3-3η level is associated with severity and clinical outcomes of rheumatoid arthritis, and its pretreatment level is predictive of DAS28 remission with tocilizumab.2015

    • Author(s)
      Hirata S, Marotta A, Gui Y, Hanami K, Tanaka Y.
    • Journal Title

      Arthritis Res Ther.

      Volume: 17 Issue: 1 Pages: 280-280

    • DOI

      10.1186/s13075-015-0799-7

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25460713, KAKENHI-PROJECT-26860764
  • [Journal Article] A multi-biomarker disease activity score tracks clinical response consistently in patients with rheumatoid arthritis treated with different anti-tumor necrosis factor therapies: A retrospective observational study.2015

    • Author(s)
      Hirata S, Li W, Defranoux N, Cavet G, Bolce R, Yamaoka K, Saito K, Tanaka Y.
    • Journal Title

      Mod Rheumatol.

      Volume: 25 Issue: 3 Pages: 344-9

    • DOI

      10.3109/14397595.2014.958893

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25460713
  • [Journal Article] Combination therapy for early rheumatoid arthritis: a treatment holiday perspective.2015

    • Author(s)
      Hirata S, Tanaka Y.
    • Journal Title

      Expert Rev Clin Pharmacol.

      Volume: 8 Issue: 1 Pages: 115-22

    • DOI

      10.1586/17512433.2015.984689

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25460713
  • [Journal Article] Discontinuation of adalimumab after achieving remission in patients with established rheumatoid arthritis: 1-year outcome of the HONOR study.2014

    • Author(s)
      Tanaka Y, Hirata S, Kubo S, Fukuyo S, Hanami K, Sawamukai N, Nakano K, Nakayamada S, Yamaoka K, Sawamura F, Saito K.
    • Journal Title

      Ann Rheum Dis

      Volume: in press Issue: 2 Pages: 389-95

    • DOI

      10.1136/annrheumdis-2013-204016

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25460713, KAKENHI-PROJECT-26860764
  • [Journal Article] Abatacept inhibits radiographic progression in patients with rheumatoid arthritis: a retrospective analysis of 6 months of abatacept treatment in routine clinical practice. The ALTAIR study.2014

    • Author(s)
      Kubo S, Saito K, Hirata S, Fukuyo S, Yamaoka K, Sawamukai N, Nawata M, Iwata S, Mizuno Y, Tanaka Y.
    • Journal Title

      Mod Rheumatol

      Volume: 24 Issue: 1 Pages: 42-51

    • DOI

      10.3109/14397595.2013.854051

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25460713
  • [Journal Article] Effects of tofacitinib on lymphocytes in rheumatoid arthritis: Relation to efficacy and infectious adverse events.2014

    • Author(s)
      Sonomoto K, Yamaoka K, Kubo S, Hirata S, Fukuyo S, Maeshima K, Suzuki K, Saito K, Tanaka Y.
    • Journal Title

      Rheumatology (Oxford).

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25460713
  • [Journal Article] A multi-biomarker disease activity score tracks clinical response consistently in patients with rheumatoid arthritis treated with different anti-tumor necrosis factor therapies: A retrospective observational study.2014

    • Author(s)
      Hirata S, Li W, Defranoux N, Cavet G, Bolce R, Yamaoka K, Saito K, Tanaka Y.
    • Journal Title

      Mod Rheumatol.

      Volume: Oct 8: 1-6. Epub

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25460713
  • [Journal Article] Primary and secondary surveys on epidemiology of Sjören's syndrome in Japan.2014

    • Author(s)
      Tsuboi H, Asashima H, Takai C, Hagiwara S, Hagiya C, Yokosawa M, Hirota T, Umehara H, Kawakami A, Nakamura H, Sano H, Tsubota K, Ogawa Y, Takamura E, Saito I, Inoue H, Nakamura S, Moriyama M, Takeuchi T, Tanaka Y, Hirata S, Mimori T, Yoshifuji H, Ohta A, Matsumoto I, Sumida T.
    • Journal Title

      Mod Rheumatol

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25460713
  • [Journal Article] Is It Possible to Withdraw Biologics From Therapy in Rheumatoid Arthritis?2014

    • Author(s)
      TanakaY, Hirata S.
    • Journal Title

      Clin Ther

      Volume: in press Issue: 12 Pages: 2028-2035

    • DOI

      10.1016/j.clinthera.2013.10.008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25460713
  • [Journal Article] Efficacy and safety of reducing duration of infliximab infusion.2014

    • Author(s)
      Fukuyo S, Saito K, Yamaoka K, Sawamukai N, Hirata S, Nawata M, Iwata S, Tanaka Y.
    • Journal Title

      Mod Rheumatol

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25460713
  • [Journal Article] Discontinuation of adalimumab after attaining disease activity score 28-erythrocyte sedimentation rate remission in patients with rheumatoid arthritis (HONOR study): an observational study.2013

    • Author(s)
      Hirata S, Saito K, Kubo S, Fukuyo S, Mizuno Y, Iwata S, Nawata M, Sawamukai N, Nakano K, Yamaoka K, Tanaka Y.
    • Journal Title

      Arthritis Res Ther

      Volume: 15 Issue: 5

    • DOI

      10.1186/ar4315

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25460713
  • [Journal Article] A multi-biomarker score measures rheumatoid arthritis disease activity in the BeSt study.2013

    • Author(s)
      Hirata S, Dirven L, Shen Y, Centola M, Cavet G, Lems WF, Tanaka Y, Huizinga TW, Allaart CF.
    • Journal Title

      Rheumatology (Oxford)

      Volume: 52 Issue: 7 Pages: 1202-7

    • DOI

      10.1093/rheumatology/kes362

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25460713
  • [Journal Article] Discontinuation of biologics in patients with rheumatoid arthritis.2013

    • Author(s)
      Tanaka Y, Hirata S, Saleem B, Emery P.
    • Journal Title

      Clin Exp Rheumatol

      Volume: 31

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25460713
  • [Presentation] リウマチ滑膜細胞のTLR4活性化研究におけるLPSのコンタミネーションの検出に、変異型LPS・Re-LPSは有用である2021

    • Author(s)
      24.河野紘輝, 應原一久, 德永忠浩, 茂久田翔, 水野智仁, 小澤龍彦, 川高正聖, 平田信太郎, 岸 裕幸, 杉山英二
    • Organizer
      第36回日本臨床リウマチ学会
    • Data Source
      KAKENHI-PROJECT-19K07940
  • [Presentation] 無治療の関節リウマチの血清反応陽性例、陰性例における血清バイオマーカー値の比較検討2021

    • Author(s)
      河野紘輝, 荒木慧, 石德理訓, 渡辺裕文, 茂久田翔, 平田信太郎, 杉山英二
    • Organizer
      第36回日本臨床リウマチ学会
    • Data Source
      KAKENHI-PROJECT-19K07940
  • [Presentation] 関節リウマチ滑膜細胞におけるシトルリン化フィブリノーゲンのCXCL10誘導作用とその機序の検討2020

    • Author(s)
      河野 紘輝, 應原 一久, 大本 卓司, 渡辺 裕文, 湯川 和俊, 徳永 忠浩, 倉信 達臣, 大井 勝博, 杉本 智裕, 吉田 雄介, 茂久田 翔, 小田 啓介, 野島 崇樹, 平田 信太郎, 杉山 英二
    • Organizer
      第64回日本リウマチ学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-19K07940
  • [Presentation] Tapering and Discontinuing Prednisolone Without Deteriorated Disease Control by Optimizing Methotrexate in Patients with Rheumatoid Arthritis Under Stable Treatment - 2-year Results in the Real-world Clinical Practice -2019

    • Author(s)
      Hirata S, Omoto T, Kohno H, Watanabe H, Yukawa K, Tokunaga T, Kuranobu T, Oi K, Yoshida Y, Sugimoto T, Mokuda S, Oda K, Nojima T, Sugiyama E
    • Organizer
      2019 ACR/ARP Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07940
  • [Presentation] Practical Optimization of Methotrexate Dose Improves Disease Control of Rheumatoid Arthritis Despite Reduction or Discontinuation of Oral Glucocorticoids.2018

    • Author(s)
      Shintaro Hirata, Kei Araki, Hiroki Kohno, Kazutoshi Yukawa, Tadahiro Tokunaga, Tatsuomi Kuranobu, Katsuhiro Oi, Yusuke Yoshida, Tomohiro Sugimoto, Keisuke Oda, Takaki Nojima, Eiji Sugiyama
    • Organizer
      ACR/ARHP2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08956
  • [Presentation] 疾患活動性評価の正確化 (Multi-biomarker disease activity(MBDA)score による活動性評価)2018

    • Author(s)
      平田信太郎
    • Organizer
      第33回日本臨床リウマチ学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K08956
  • [Presentation] OPTIMISATION OF METHOTREXATE DOSE INDUCED SUCCESSFUL REDUCTION OF GLUCOCORTICOIDS WITHOUT IMPAIRED DISEASE CONTROL IN PATIENTS WITH RHEUMATOID ARTHRITIS.2018

    • Author(s)
      251.S. Hirata, T. Kondo, K. Yukawa, T. Tokunaga, T. Kuranobu, K. Oi, Y. Yoshida, M. Funaki, K. Oda, T. Nojima, E. Sugiyama
    • Organizer
      EULAR2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08956
  • [Presentation] 血清14-3-3ηは関節リウマチ患者のトシリツマブ治療反応性を予測できる2017

    • Author(s)
      田中良哉、平田信太郎、花見健太郎、Anthony Marotta
    • Organizer
      第61回日本リウマチ学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-16K08956
  • [Presentation] 血清14-3-3ηによる関節リウマチ患者に於けるアダリムマブ(ADA)治療中止後の関節破壊進行と再燃の予測2017

    • Author(s)
      田中良哉、平田信太郎、花見健太郎、Anthony Marotta
    • Organizer
      第61回日本リウマチ学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-16K08956
  • [Presentation] 当科開設以来の関節リウマチ(RA)に対する生物学的抗リウマチ薬(bDMARDs)選択と継続に関する検討.2017

    • Author(s)
      平田信太郎、近藤拓馬、湯川和俊、德永忠浩、倉信達臣、大井勝博、吉田雄介、舟木将雅、小田啓介、野島崇樹、杉山英二
    • Organizer
      第28回日本リウマチ学会中国・四国支部学術集会
    • Data Source
      KAKENHI-PROJECT-16K08956
  • [Presentation] MULTICENTER 14-3-3ETA BIOMARKER REPRODUCIBILITY; THE JAPANESE EXPERIENCE.2017

    • Author(s)
      S. Hirata, M. Kaneda, T. Isayama, Y. Gui, A. Marotta, W. P. Maksymowych, Y. Tanaka.
    • Organizer
      EULAR 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08956
  • [Presentation] 14-3-3ETA PREDICTS JOINT DAMAGE PROGRESSION AND FLARING AFTER ADALIMUMAB DISCONTINUATION.2017

    • Author(s)
      S. Hirata, A. Marotta, K. Hanami, Y. Tanaka.
    • Organizer
      EULAR 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08956
  • [Presentation] 関節リウマチに伴う間質性肺疾患(RA-ILD)に対するタクロリムス(TAC)の有効性2017

    • Author(s)
      平田信太郎、中野和久、久保智史、杉山英二、田中良哉
    • Organizer
      第61回日本リウマチ学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-16K08956
  • [Presentation] Predicting Flare and Sustained Clinical Remission after Adalimumab Withdrawal Using the Multi-Biomarker Disease Activity (MBDA) Score2016

    • Author(s)
      Shintaro Hirata, Xingbin Wang, CC Hwang, Ippei Miyagawa, Satoshi Kubo, Kazuhisa Nakano, Shingo Nakayamada, Kazuyoshi Saito, Nadine A. Defranoux, Yoshiya Tanaka
    • Organizer
      ACR/ARHP 2016
    • Place of Presentation
      Washington DC, USA
    • Year and Date
      2016-11-06
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08956
  • [Presentation] Lower Baseline 14-3-3η Levels Are Associated with Better Patient Reported Outcomes in Tocilizumab Treated Patients2016

    • Author(s)
      Shintaro Hirata, Anthony Marotta, Kentaro Hanami, Yoshiya Tanaka
    • Organizer
      ACR/ARHP 2016
    • Place of Presentation
      Washington DC, USA
    • Year and Date
      2016-11-06
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08956
  • [Presentation] PREDICTIVE VALUE OF THE MULTI-BIOMARKER DISEASE ACTIVITY (MBDA) SCORE FOR FLARE AND SUSTAINED REMISSION IN THE HONOR STUDY2016

    • Author(s)
      S. Hirata, S. Tang, C.C. Hwang, I. Miyagawa, S. Kubo, K. Nakano, S. Nakayamada, K. Saito, N.A. Defranoux, Y. Tanaka
    • Organizer
      EULAR2016
    • Place of Presentation
      London, UK
    • Year and Date
      2016-06-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08956
  • [Presentation] BASELINE SERUM 14-3-3 ETA INDEPENDENTLY PREDICTS CLINICALLY IMPORTANT IMPROVEMENTS IN HAQ-DI IN PATIENTS WITH RHEUMATOID ARTHRITIS TREATED WITH TOCILIZUMAB2016

    • Author(s)
      S. Hirata, K. Hanami, A. Marotta, Y. Tanaka
    • Organizer
      EULAR2016
    • Place of Presentation
      London, UK
    • Year and Date
      2016-06-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08956
  • [Presentation] ANTI-JAK IS ANTI-FIBROTIC IN PATIENTS WITH RHEUMATOID ARTHRITIS2016

    • Author(s)
      S. Hirata, N.S. Gudmann, S. Kubo, M. Karsdal, A.C. Bay-Jensen, Y. Tanaka
    • Organizer
      EULAR2016
    • Place of Presentation
      London, UK
    • Year and Date
      2016-06-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08956
  • [Presentation] 関節リウマチにおいてベースライン14-3-3η低値はtocilizumabによる1年後のDAS28-ESR寛解達成を予測する.2015

    • Author(s)
      平田信太郎, 花見健太郎, 山形 薫, 宮川一平, 久保智史, 岩田慈, 澤向範文, 中野和久, 中山田真吾, 齋藤和義, Anthony Marotta, 田中良哉
    • Organizer
      第43回日本臨床免疫学会
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Year and Date
      2015-10-22
    • Data Source
      KAKENHI-PROJECT-25460713
  • [Presentation] Predictive value of the MBDA score and composite measures for sustained remission at 1 year after withdrawal of adalimumab in the HONOR study2015

    • Author(s)
      Shintaro Hirata, Kentaro Hanami, Nadine Defranoux, Ippei Miyagawa, Satoshi Kubo, Shunsuke Fukuyo, Norifumi Sawamukai, Kazuhisa Nakano, Shingo Nakayamada, Kazuyoshi Saito, Yoshiya Tanaka
    • Organizer
      第59回日本リウマチ学会総会・学術集会 (JCR2015)
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2015-04-23
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25460713
  • [Presentation] Neo-epitopes of connective tissue turnover are biomarkers of disease activity and modulated in response to tofacitinib or tocilizumab in rheumatoid arthritis2015

    • Author(s)
      Shintarto Hirata, Natasja S. Gudmann, Morten Karsdal, Anne C. Bay-Jensen, Yoshiya Tanaka
    • Organizer
      EULAR2015
    • Place of Presentation
      Rome, Italy
    • Year and Date
      2015-06-10
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25460713
  • [Presentation] The relevance of serum 14-3-3η levels to clinical and radiographic outcomes in patients with rheumatoid arthritis2015

    • Author(s)
      Shintaro Hirata, Kentaro Hanami, Kaoru Yamagata, Ippei Miyagawa, Satoshi Kubo, Shunsuke Fukuyo, Norifumi Sawamukai, Kazuhisa Nakano, Shingo Nakayamada, Kazuyoshi Saito, Anthony Marotta, Yoshiya Tanaka
    • Organizer
      第59回日本リウマチ学会総会・学術集会 (JCR2015)
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2015-04-23
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25460713
  • [Presentation] JAK Inhibition Significantly Reduced Fibrogenesis in Rheumatoid Arthritis Patients2015

    • Author(s)
      Shintaro Hirata, Natasja Stæhr Gudman, Kentaro Hanami, Satoshi Kubo, Anne C. Bay-Jensen, Morten Asser Karsdal, Yoshiya Tanaka
    • Organizer
      ACR2015
    • Place of Presentation
      San Francisco, United States
    • Year and Date
      2015-11-06
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25460713
  • [Presentation] 14-3-3η Positive Status and Higher Titres Are Associated with More Severe RA2015

    • Author(s)
      Shintaro Hirata, Kentaro Hanami, Anthony Marotta, Yoshiya Tanaka
    • Organizer
      ACR2015
    • Place of Presentation
      San Francisco, United States
    • Year and Date
      2015-11-06
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25460713
  • [Presentation] Multi-biomarker disease activity (MBDA)スコアは関節リウマチにおける最も鋭敏に構造的寛解を予測、反映する疾患活動性マーカーである2013

    • Author(s)
      平田 信太郎, 齋藤 和義, 久保 智史, 福與 俊介, 水野 泰志, Wanying Li, Douglas J. Haney, Nadine Defranoux, Rebecca Bolce, Guy Cavet, 園本 格士朗,花見 健太郎, 岩田 慈, 名和田 雅夫, 澤向 範文, 中野 和久, 中山田 真吾, 山岡 邦宏、田中 良哉
    • Organizer
      第57回日本リウマチ学会総会・学術集会(JCR2013)
    • Place of Presentation
      京都(国立京都国際会館)
    • Data Source
      KAKENHI-PROJECT-25460713
  • [Presentation] BEHAVIOR OF THE MULTI-BIOMARKER DISEASE ACTIVITY (VECTRA® DA ALGORITHM) SCORE AND COMPONENTS IN PATIENTS WITH RHEUMATOID ARTHRITIS TREATED WITH TOCILIZUMAB2013

    • Author(s)
      K.Hanami, S.Hirata, H.Tasaka, W.Li, R.Bolce, E.H.Sasso, N.A.Defranoux, K.Yamaoka, K.Saito, Y.Tanaka
    • Organizer
      EULAR2013
    • Place of Presentation
      Madrid, Spain
    • Data Source
      KAKENHI-PROJECT-25460713
  • [Presentation] A MULTI-BIOMARKER DISEASE ACTIVITY (VECTRA™ DA ALGORITHM) SCORE IS ASSOCIATED WITH RADIOGRAPHIC OUTCOMES IN RA PATIENTS TREATED WITH TNF INHIBITORS2013

    • Author(s)
      S.Hirata, W.Li, N.A.Defranoux, R.Bolce, D.J.Haney, E.H.Sasso, S.Kubo, S.Fukuyo, Y.Mizuno, K.Yamaoka, K.Saito, Y.Tanaka
    • Organizer
      EULAR2013
    • Place of Presentation
      Madrid, Spain
    • Data Source
      KAKENHI-PROJECT-25460713
  • [Presentation] 血清MMP-3はTNF阻害療法下の関節リウマチにおける関節裂隙狭小化スコアと相関性が高い2013

    • Author(s)
      平田 信太郎, 齋藤 和義, 久保 智史, 福與 俊介, 水野 泰志, 園本 格士朗, 花見 健太郎, 岩田 慈, 名和田 雅夫, 澤向 範文, 中野 和久, 中山田 真吾, 山岡 邦宏, 田中 良哉
    • Organizer
      第57回日本リウマチ学会総会・学術集会(JCR2013)
    • Place of Presentation
      京都(国立京都国際会館)
    • Data Source
      KAKENHI-PROJECT-25460713
  • [Presentation] A novel peripheral blood derived multi-biomarker disease activity (MBDA; Vectra™ DA Algorithm) score reflects clinical, functional, and radiographic outcomes in Japanese rheumatoid arthritis patients treated with TNF inhibitors2013

    • Author(s)
      Shintaro Hirata, Wanying Li, Nadine A. Defranoux, Rebecca Bolce, Kentaro Hanami, Satoshi Kubo, Shunsuke Fukuyo, Yasushi Mizuno, Kunihiro Yamaoka, Kazuyoshi Saito, Yoshiya Tanaka
    • Organizer
      EAGOR2013
    • Place of Presentation
      Seoul, South Korea
    • Data Source
      KAKENHI-PROJECT-25460713
  • [Presentation] REPEATED HIGH OR LOW MULTI-BIOMARKER DISEASE ACTIVITY (VECTRA® DA ALGORITHM) SCORES ASSOCIATED WITH RADIOGRAPHIC OUTCOMES IN PATIENTS WITH RA TREATED WITH TNF INHIBITORS2013

    • Author(s)
      S.Hirata, W.Li, N.A.Defranoux, R.Bolce, E.H.Sasso, S.Kubo, S.Fukuyo, Y.Mizuno, K.Yamaoka, K.Saito, Y.Tanaka
    • Organizer
      ACR2013
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PROJECT-25460713
  • [Presentation] Analysis of clinical factors for achieving to EULAR low disease activity at 24 weeks with adalimumab in patients with RA.2010

    • Author(s)
      Hirata S, Saito K, Tsujimura S, Nakano K, Yamaoka K, Tanaka
    • Organizer
      International Workshop, The 54th Annual General Assembly and Scientific Meeting of The Japan College of Rheumagoloty
    • Place of Presentation
      Kobe
    • Year and Date
      2010-04-22
    • Data Source
      KAKENHI-PROJECT-21790953
  • [Presentation] 膠原病合併IPに対するTacrolimusの有用性-Global composite measureによる評価の試み2010

    • Author(s)
      平田信太郎, 齋藤和義, 久保智史, 辻村静代, 中野和久, 山岡邦宏, 田中良哉
    • Organizer
      第54回日本リウマチ学会総会・学術集会
    • Place of Presentation
      神戸
    • Year and Date
      2010-04-24
    • Data Source
      KAKENHI-PROJECT-21790953
  • [Presentation] サイトカインを標的とした病態制御の可能性関節リウマチにおける完全ヒトTNFα抗体Adalimumabの疾患活動性制御に関与する背景因子の検討2010

    • Author(s)
      平田信太郎, 齋藤和義, 名和田雅夫, 辻村静代, 中野和久, 山岡邦宏, 田中良哉
    • Organizer
      第31回日本炎症・再生医学会
    • Place of Presentation
      東京
    • Year and Date
      2010-08-05
    • Data Source
      KAKENHI-PROJECT-21790953
  • [Presentation] Adalimumab(ADA)にて24週後に低疾患活動性(LDA)を達成する症例の背景因子の検討2010

    • Author(s)
      平田信太郎, 齋藤和義, 辻村静代, 中野和久, 山岡邦宏, 田中良哉
    • Organizer
      第54回日本リウマチ学会総会・学術集会
    • Place of Presentation
      神戸
    • Year and Date
      2010-04-24
    • Data Source
      KAKENHI-PROJECT-21790953
  • [Presentation] 膠原病合併間質性肺炎に対するcomposite measureを用いたタクロリムスの有用性の検討2010

    • Author(s)
      平田信太郎, 齋藤和義, 久保智史, 辻村静代, 中野和久, 山岡邦宏, 田中良哉
    • Organizer
      第39回九州リウマチ学会
    • Place of Presentation
      福岡
    • Year and Date
      2010-03-06
    • Data Source
      KAKENHI-PROJECT-21790953
  • [Presentation] 当科におけるアダリムマブ24週投与の解析アダリムマブの効果予測の可能性2009

    • Author(s)
      平田信太郎, 齋藤和義, 久保智史, 宮川一平, 福與俊介, 花見健太郎, 湯川宗之助, 岩田慈, 名和田雅夫, 辻村静代, 中野和久, 山岡邦宏, 田中良哉
    • Organizer
      第38回九州リウマチ学会
    • Place of Presentation
      久留米
    • Year and Date
      2009-09-05
    • Data Source
      KAKENHI-PROJECT-21790953
  • [Presentation] 膠原病に伴う間質性肺炎に対するタクロリムスの有用性の検討2009

    • Author(s)
      平田信太郎, 中野和久, 齋藤和義, 久保智史, 鈴木克典, 名和田雅夫, 澤向範文, 山岡邦宏, 田中良哉
    • Organizer
      第53回日本リウマチ学会総会・学術集会
    • Place of Presentation
      東京
    • Year and Date
      2009-04-23
    • Data Source
      KAKENHI-PROJECT-21790953
  • [Presentation] 関節リウマチに対するadalimumab(ADA)の早期有効性に関与する因子の検討2009

    • Author(s)
      平田信太郎, 齋藤和義, 花見健太郎, 岩田慈, 名和田雅夫, 澤向範文, 中野和久, 山岡邦宏, 田中良哉
    • Organizer
      第53回日本リウマチ学会総会・学術集会
    • Place of Presentation
      東京
    • Year and Date
      2009-04-24
    • Data Source
      KAKENHI-PROJECT-21790953
  • [Presentation] TNF阻害療法下のRA患者におけるmulti-biomarker disease activity (MBDA)スコアと関節破壊進行に関する検討

    • Author(s)
      平田信太郎, 齋藤和義, 久保智史, 福與俊介, 水野泰志, Wanying Li, Nadine A. Defranoux, Rebecca Bolce, Eric Sasso, 宮川一平,花見健太郎, 澤向範文, 中野和久, 中山田真吾, 山岡邦宏、田中良哉
    • Organizer
      第58回日本リウマチ学会総会・学術集会 (JCR2014)
    • Place of Presentation
      グランドプリンスホテル新高輪(東京都港区)
    • Year and Date
      2014-04-24 – 2014-04-26
    • Data Source
      KAKENHI-PROJECT-25460713
  • [Presentation] Neo-epitopes of connective tissue turnover are biomarkers of disease activity and modulated in response to tofacitinib or tocilizumab in rheumatoid arthritis

    • Author(s)
      Shintarto Hirata, Natasja S. Gudmann, Morten Karsdal, Anne C. Bay-Jensen, Yoshiya Tanaka
    • Organizer
      The Annual European Congress of Rheumatology EULAR 2015
    • Place of Presentation
      Fiera Roma, Rome, Italy
    • Year and Date
      2015-06-10 – 2015-06-13
    • Data Source
      KAKENHI-PROJECT-25460713
  • [Presentation] 14-3-3eta Informs Joint Pathological Mechanisms of Treatment Response to Assist with T2T Strategies

    • Author(s)
      Shintaro Hirata, Kentaro Hanami, Anthony Marotta, Yoshiya Tanaka
    • Organizer
      2014 ACR/ARHP Annual Meeting
    • Place of Presentation
      Boston Convention & Exhibition Center, Boston, Massachusetts, USA
    • Year and Date
      2014-11-14 – 2014-11-19
    • Data Source
      KAKENHI-PROJECT-25460713
  • 1.  應原 一久 (80550425)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 2.  庄子 幹郎 (10336175)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  小澤 龍彦 (10432105)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  原田 陽介 (10464314)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  柳井 亮二 (10346554)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  土居 岳彦 (20572100)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  木内 良明 (40214738)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  田中 武志 (40325197)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  吉田 雄介 (60772051)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  日山 知奈 (10984437)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  茂久田 翔
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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