SUZUKI Takeo 鈴木健夫

Researcher Number	90533125
Affiliation (Current)	2019: 東京大学, 大学院工学系研究科(工学部), 講師
Affiliation (based on the past Project Information) *help	2017 – 2019: 東京大学, 大学院工学系研究科(工学部), 講師 2011 – 2016: 東京大学, 工学(系)研究科(研究院), 講師 2013: 東京大学, 大学院工学系研究科, 講師 2012: 東京大学, 工学(系)研究科(研究院), 助教 2011 – 2012: 東京大学, 大学院・工学系研究科, 講師 2009 – 2010: 東京大学, 大学院・工学系研究科, 助教 2009: 東京大学, 工学(系)研究科, 助教
Review Section/Research Field	Principal Investigator Chemical biology / Medium-sized Section 37:Biomolecular chemistry and related fields / Chemical biology / Basic Section 37020:Chemistry and chemical methodology of biomolecules-related / Biological Sciences / Biomolecular chemistry Except Principal Investigator Living organism molecular science / Biological Sciences
Keywords	Principal Investigator RNA修飾 / 生合成 / 修飾酵素 / tRNA / LC/MS / デコーディング / 転写後修飾 / RNA / ｔRNA / ミトコンドリア … More Except Principal Investigator 修飾塩基 / リボソーム / tRA Ile2 / tRNA / 遺伝子 / ゲノム / X線結晶構造解析 / Lysidine / 結晶構造解析 / コドン認識 / 核酸 / 発現制御 / タンパク質合成 / 蛋白質 / 超分子複合 Less

希少なRNA修飾の機能究明と動的調節機構の提唱Principal InvestigatorOngoing
- Principal Investigator
  
  鈴木健夫
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 37020:Chemistry and chemical methodology of biomolecules-related
- Research Institution
  The University of Tokyo
Research for an mRNA modication specific to vertebratesPrincipal InvestigatorOngoing
- Principal Investigator
  
  鈴木健夫
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 37:Biomolecular chemistry and related fields
- Research Institution
  The University of Tokyo
Exploring RNA modifications using enzymatic probe and its applicationsPrincipal Investigator
- Principal Investigator
  
  Suzuki Takeo
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Chemical biology
- Research Institution
  The University of Tokyo
Biosynthesis and function of characteristic RNA modifications found in humanPrincipal Investigator
- Principal Investigator
  
  Suzuki Takeo
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Biomolecular chemistry
- Research Institution
  The University of Tokyo
Biosynthetic mechanism of the wobble modified uridines in tRNAPrincipal Investigator
- Principal Investigator
  
  SUZUKI Takeo
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Chemical biology
- Research Institution
  The University of Tokyo
Structural bases for an expanded codon recognition by modified nucleotide.
- Principal Investigator
  
  TAKEMOTO Chi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Living organism molecular science
- Research Institution
  The Institute of Physical and Chemical Research
Functional machinery for non-coding RNAs
- Principal Investigator
  
  TOMARI Yukihide
- Project Period (FY)
  2009 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Structural and functional analysis of non-coding RNA machineriesPrincipal Investigator
- Principal Investigator
  
  SUZUKI Takeo
- Project Period (FY)
  2009 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo

All 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 Other

All Journal Article Presentation

[Journal Article] Defective mitochondrial tRNA taurine modification activates global protcostress and leads to mitochondrial disease.2018
- Author(s)
  Fakruddin, M., Wei, F. Y., Suzuki, T., Asano, K., Kaieda, T., Omori, A., Izumi, R., Fujimura, A., Kaitsuka, T., Miyata, K., Araki, K., Oike, Y., Scorrano, L., Suzuki, T. and Tomizawa, K.
- Journal Title
  
  Coll Rep.
  
  Volume: 22 Pages: 482-496
- DOI
  10.1016/j.celrep.2017.12.051
- Open Access / Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17KT0054, KAKENHI-PROJECT-26702035, KAKENHI-PROJECT-26220205, KAKENHI-PROJECT-16K15482, KAKENHI-PROJECT-16H06276
[Journal Article] Metabolic and chemical regulation of tRNA modification associated with taurine deficiency and human disease2018
- Author(s)
  Asano Kana、Suzuki Takeo、Saito Ayaka、Wei Fan-Yan、Ikeuchi Yoshiho、Numata Tomoyuki、Tanaka Ryou、Yamane Yoshihisa、Yamamoto Takeshi、Goto Takanobu、Kishita Yoshihito、Murayama Kei、Ohtake Akira、Okazaki Yasushi、Tomizawa Kazuhito、Sakaguchi Yuriko、Suzuki Tsutomu
- Journal Title
  
  Nucleic Acids Res.
  
  Volume: 46 Pages: 1565-1583
- DOI
  10.1093/nar/gky068
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26702035, KAKENHI-PROJECT-26220205, KAKENHI-PROJECT-16H04759
[Journal Article] Identification of 2-methylthio cyclic N6-threonylcarbamoyladenosine (ms2ct6A) as a novel RNA modification at position 37 of tRNAs2017
- Author(s)
  Kang, B. I., Miyauchi, K., Matuszewski, M., D'Almeida, G. S., Rubio, M. A., Alfonzo, J. D., Inoue, K., Sakaguchi, Y., Suzuki, T., Sochacka, E., Suzuki, T.
- Journal Title
  
  Nucleic Acids Res.
  
  Volume: 45 Pages: 2124-2136
- DOI
  10.1093/nar/gkw1120
- Open Access / Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26702035, KAKENHI-INTERNATIONAL-15K21720, KAKENHI-PLANNED-26113003, KAKENHI-PROJECT-26220205
[Journal Article] ALKBH1 is an RNA dioxygenase responsible for cytoplasmic and mitochondrial tRNA modifications2017
- Author(s)
  Kawarada Layla、Suzuki Takeo、Ohira Takayuki、Hirata Shoji、Miyauchi Kenjyo、Suzuki Tsutomu
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 45 Pages: 7401-7415
- DOI
  10.1093/nar/gkx354
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26702035, KAKENHI-PROJECT-26220205
[Journal Article] Mtu1-mediated thiouridine formation of mitochondrial tRNAs is required for mitochondrial translation and is involved in reversible infantile liver2016
- Author(s)
  Wu, Y., Wei, F. Y., Kawarada, L., Suzuki, T., Araki, K., Komohara, Y., Fujimura, A., Kaitsuka, T., Takeya, M., Oike, Y., Suzuki, T., Tomizawa, K.
- Journal Title
  
  PLoS Genet.
  
  Volume: 12
- DOI
  10.1371/journal.pgen.1006355
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26702035, KAKENHI-PROJECT-15K08178, KAKENHI-PROJECT-16K07093, KAKENHI-PROJECT-16K18989, KAKENHI-PLANNED-26113003, KAKENHI-PROJECT-26220205
[Journal Article] NSUN3 methylase initiates 5-formylcytidine biogenesis in human mitochondrial tRNAMet2016
- Author(s)
  Nakano, S., Suzuki, T., Kawarada, L., Iwata, H., Asano, K., Suzuki, T.
- Journal Title
  
  Nature Chem Biol.
  
  Volume: 12 Pages: 546-51
- DOI
  10.1038/nchembio.2099
- Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26702035, KAKENHI-PLANNED-26113003, KAKENHI-PROJECT-26220205
[Journal Article] Cdk5rap1-mediated 2-methylthio modification of mitochondrial tRNAs governs precise protein translation and contributes to myopathy in mice and humans2015
- Author(s)
  Wei FY, Zhou B, Suzuki T, Miyata K, Ujihara Y, Horiguchi H, Takahashi N, Xie P, Michiue H, Fujimura A, Kaitsuka T, Matsui H, Koga Y, Mohri S, Suzuki T, Oike Y, Tomizawa K.
- Journal Title
  
  Cell Metabolism
  
  Volume: 21 Pages: 428-42
- DOI
  10.1016/j.cmet.2015.01.019
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390293, KAKENHI-PROJECT-24791502, KAKENHI-PROJECT-25461114, KAKENHI-PROJECT-25461571, KAKENHI-PROJECT-25620125, KAKENHI-PUBLICLY-26116722, KAKENHI-PROJECT-26220205, KAKENHI-PROJECT-26282127, KAKENHI-PROJECT-26293190, KAKENHI-PROJECT-26560442, KAKENHI-PROJECT-26670405, KAKENHI-PROJECT-26702035, KAKENHI-PROJECT-15K08178, KAKENHI-PLANNED-26113003, KAKENHI-PROJECT-26670284
[Journal Article] Single methylation of 23S rRNA triggers late steps of 50S ribosomal subunit assembly2015
- Author(s)
  Arai, T., Ishiguro, K., Kimura, S., Sakaguchi, Y., Suzuki, T., Suzuki, T.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA.
  
  Volume: 112
- DOI
  10.1073/pnas.1506749112
- Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26560442, KAKENHI-PROJECT-26702035, KAKENHI-ORGANIZER-26113001, KAKENHI-PLANNED-26113003, KAKENHI-PROJECT-26220205
[Journal Article] RNAの修飾欠損と疾患2015
- Author(s)
  鈴木勉、浅野奏、鈴木健夫
- Journal Title
  
  ファルマシア
  
  Volume: 51 Pages: 32-36
- Data Source
  KAKENHI-PROJECT-26702035
[Journal Article] RNAの修飾欠損と疾患2015
- Author(s)
  鈴木勉、浅野奏、鈴木健夫
- Journal Title
  
  ファルマシア
  
  Volume: 51 Pages: 32-36
- Data Source
  KAKENHI-PROJECT-26560442
[Journal Article] 5hmC plays a critical role in glioblastomagenesis by recruiting the CHTOP-methylosome complex2014
- Author(s)
  Hiroki Takai, Tetsu Akiyama et al.
- Journal Title
  
  Cell Rep
  
  Volume: 9 Pages: 48-60
- DOI
  10.1016/j.celrep.2014.08.071
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-14J10908, KAKENHI-ORGANIZER-22112001, KAKENHI-PLANNED-22112004, KAKENHI-PROJECT-24390340, KAKENHI-PROJECT-24501313, KAKENHI-PUBLICLY-25134702, KAKENHI-PROJECT-25620125, KAKENHI-PROJECT-26220205, KAKENHI-PROJECT-26253073, KAKENHI-PROJECT-26293321, KAKENHI-PROJECT-26560442, KAKENHI-PROJECT-26702035, KAKENHI-PLANNED-23114003, KAKENHI-PLANNED-26113003
[Journal Article] Structural dynamics of a mitochondrial tRNA possessing weak thermodynamic stability2014
- Author(s)
  Hari Bhaskaran, Takaaki Taniguchi, Takeo Suzuki, Tsutomu Suzuki, and John J. Perona
- Journal Title
  
  Biochemistry
  
  Volume: 53(a) Pages: 1456-1465
- DOI
  10.1021/bi401449z
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J09837, KAKENHI-PLANNED-21115003, KAKENHI-PROJECT-22227006, KAKENHI-PROJECT-25620125
[Journal Article] A complete landscape of post-transcriptional modifications in mammalian mitochondrial tRNAs2014
- Author(s)
  Suzuki T. and Suzuki T.
- Journal Title
  
  Nucleic Acids Res
  
  Volume: (in press) Pages: 7346-57
- DOI
  10.1093/nar/gku390
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21115003, KAKENHI-PROJECT-22227006, KAKENHI-PROJECT-25620125, KAKENHI-PROJECT-26220205, KAKENHI-PROJECT-26560442, KAKENHI-PROJECT-26702035, KAKENHI-PLANNED-26113003
[Journal Article] Biochemical and mass spectrometric analysis of 3'-end methylation of piRNAs2014
- Author(s)
  Suzuki T, Miyauchi K, Sakaguchi Y, Suzuki T
- Journal Title
  
  Methods in Mol Biol.
  
  Volume: 1093 Pages: 59-72
- DOI
  10.1007/978-1-62703-694-8_6
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-21115003, KAKENHI-PROJECT-22227006, KAKENHI-PROJECT-25620125
[Journal Article] A single acetylation of 18S rRNA is essential for biogenesis of the small ribosomal subunit in Saccharomyces cerevisiae.2014
- Author(s)
  Ito, S., Akamatsu, Y., Noma, A., Kimura, S., Miyauchi, K., Ikeuchi, Y., Suzuki, T. and Suzuki, T
- Journal Title
  
  J Biol Chem
  
  Volume: 289 Pages: 26201-12
- DOI
  10.1074/jbc.m114.593996
- Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25620125, KAKENHI-PROJECT-26220205, KAKENHI-PROJECT-26560442, KAKENHI-PROJECT-26702035, KAKENHI-PLANNED-26113003
[Journal Article] Human NAT10 Is an ATP-dependent RNA Acetyltransferase Responsible for N4-Acetylcytidine Formation in 18 S Ribosomal RNA (rRNA)2014
- Author(s)
  Satoshi Ito, Sayuri Horikawa, Tateki Suzuki, Hiroki Kawauchi, Yoshikazu Tanaka, Takeo Suzuki, and Tsutomu Suzuki
- Journal Title
  
  J Biol Chem
  
  Volume: 289 Pages: 35724-30
- DOI
  10.1074/jbc.c114.602698
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-25620125, KAKENHI-PUBLICLY-26102501, KAKENHI-PROJECT-26220205, KAKENHI-PROJECT-26291008, KAKENHI-PROJECT-26560442, KAKENHI-PROJECT-26702035, KAKENHI-PLANNED-26113003
[Journal Article] Decoding mechanism of non-universal genetic codes in Lologo bleekeri mitochondria2013
- Author(s)
  Ohira T, Suzuki T (第2著者), 他5名
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 288 Pages: 7645-7652
- DOI
  10.1074/jbc.m112.439554
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21115003, KAKENHI-PROJECT-22227006, KAKENHI-PROJECT-23655153, KAKENHI-PROJECT-23710265, KAKENHI-PROJECT-24370093, KAKENHI-PUBLICLY-23112705
[Journal Article] The comprehensive epigenome map of piRNA clusters2013
- Author(s)
  Kawaoka S, Hara K, Shoji K, Kobayashi M, Shimada T, Sugano S, Tomari Y, Suzuki Y, Katsuma S
- Journal Title
  
  Nucleic Acids Res
  
  Volume: 41(3) Pages: 1581-1590
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-21115001
[Journal Article] Quantitative PCR measurement of tRNA 2-methylthio modification for assessing type 2 diabetes risk.2013
- Author(s)
  Kie, Pei-Yu, et al.
- Journal Title
  
  Clinical Chemistry,
  
  Volume: 59 Pages: 1604-1612
- DOI
  10.1373/clinchem.2013.210401
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12F02425, KAKENHI-PLANNED-21115003, KAKENHI-PROJECT-22227006, KAKENHI-PROJECT-25620125, KAKENHI-PROJECT-25860753
[Journal Article] Crystal structure of a putative methyltransferase SAV1081 from Staphylococcus aureus2013
- Author(s)
  Kita, S., Tanaka, Y., Hirano, N., Kimura, S., Suzuki, T., Suzuki, T., Yao, M. and Tanaka, I.
- Journal Title
  
  Protein Peptide Letters
  
  Volume: 20 Pages: 530-537
- DOI
  10.2174/0929866511320050006
- Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22227006, KAKENHI-PROJECT-23710265, KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-25620125, KAKENHI-PLANNED-21115003
[Journal Article] Targeted gene silencing in mouse germ cells by insertion of a homologous DNA into a piRNA generating locus2013
- Author(s)
  Yamamoto Y, Watanabe T, Hoki Y, Shirane K, Li Y, Ichiiyanagi K, Kuramochi-Miyagawa S, Toyoda A, Fujiyama A, Oginuma M, Suzuki H, Sado T, Nakano T, Sasaki H
- Journal Title
  
  Genome Res
  
  Volume: 23(2) Pages: 292-299
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-21115001
[Journal Article] Hsp90 facilitates accurate loading of precursor piRNAs into PIWI proteins2013
- Author(s)
  Izumi N, Kawaoka S, Yasuhara S, Suzuki Y, Sugano S, Katsuma S, Tomari Y.
- Journal Title
  
  RNA
  
  Volume: 19(7) Pages: 896-901
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-21115001
[Journal Article] A role for transcription from a piRNA cluster in de novo piRNA production2012
- Author(s)
  Kawaoka S, Mitsutake H, Kiuchi T, Kobayashi M, Yoshikawa M, Suzuki Y, Sugano S, Shimada T, Kobayashi J, Tomari Y, Katsuma S
- Journal Title
  
  RNA
  
  Volume: 18(2) Pages: 265-273
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-21115001
[Journal Article] Base methylations in the double-stranded RNA by a fused methyltransferase bearing unwinding activity.2012
- Author(s)
  Kimura S., Ikeuchi Y., Kitahara K., Sakaguchi Y., Suzuki T., Suzuki T.
- Journal Title
  
  Nucleic Acids Res
  
  Volume: (掲載確定)(印刷中) Pages: 4071-4085
- DOI
  10.1093/nar/gkr1287
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J09964, KAKENHI-PLANNED-21115003, KAKENHI-PROJECT-22227006, KAKENHI-PUBLICLY-23112705, KAKENHI-PROJECT-23655153, KAKENHI-PROJECT-23710265, KAKENHI-ORGANIZER-20112001
[Journal Article] Loss of ribosomal RNA modification causes developmental defects in zebrafish.2012
- Author(s)
  Higa-Nakamine, S., Suzuki, T., Uechi, T., Chakraborty, A., Nakajima, Y., Nakamura, M., Hirano, N., Suzuki, T. and Kenmochi, N.
- Journal Title
  
  Nucleic Acids Rresearch
  
  Volume: 40 Pages: 391-398
- DOI
  10.1093/nar/gkr700
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22227006, KAKENHI-PROJECT-22370065, KAKENHI-PROJECT-22659186, KAKENHI-PUBLICLY-23112705, KAKENHI-PROJECT-23500451, KAKENHI-PROJECT-23655153, KAKENHI-PROJECT-24659476, KAKENHI-PROJECT-24700381, KAKENHI-PLANNED-21115003, KAKENHI-PROJECT-22790989, KAKENHI-PROJECT-23710265
[Journal Article] Actin-binding protein ABP140 is a methyltransferase for 3-methylcytidine at position 32 of tRNAs in Saccharomycescerevisiae2011
- Author(s)
  Noma A, Yi S, Katoh T, Takai Y, Suzuki T and Suzuki T
- Journal Title
  
  RNA
  
  Volume: 17 Pages: 1111-1119
- DOI
  10.1261/rna.2653411
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21115003, KAKENHI-PROJECT-21227005, KAKENHI-PROJECT-22227006, KAKENHI-PUBLICLY-23112705, KAKENHI-PROJECT-23710265
[Journal Article] Molecular basis of dihydrouridine formation on tRNA.2011
- Author(s)
  Yu F, Tanaka Y, Yamashita K, Suzuki T (第4著者), 他4名
- Journal Title
  
  Proc Natl Acad SciU S A
  
  Volume: 108 Pages: 19593-19598
- DOI
  10.1073/pnas.1112352108
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21115003, KAKENHI-PROJECT-22227006, KAKENHI-PUBLICLY-23112705, KAKENHI-PROJECT-23655153, KAKENHI-PROJECT-23710265
[Journal Article] Human Mitochondrial tRNAs: Biogenesis, Function, Structural Aspects, and Diseases.2011
- Author(s)
  Tsutomu Suzuki, Asuteka Nagao and Takeo Suzuki
- Journal Title
  
  Annu. Rev. Genet.
  
  Volume: 45 Pages: 299-329
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23710265
[Journal Article] Taurine-containing uridine modifications in tRNA anticodons are required to decipher non-universal genetic codes in ascidian mitochondria2011
- Author(s)
  Takeo Suzuki, Kenjyo Miyauchi, Tsutomu Suzuki, Shin-ichi Yokobori, Naoki Shigi, Akiko Kondow, Nono Takeuchi, Akihiko Yamagishi, Kimitsuna Watanabe
- Journal Title
  
  J.Biol.Chem.
  
  Volume: 286 Pages: 35494-8
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21115003
[Journal Article] Human mitochondrial diseases caused by lack of taurine-modification in mitochondrial tRNAs2011
- Author(s)
  Suzuki, T., et al.
- Journal Title
  
  WIREs RNA
  
  Volume: 2 Pages: 376-386
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21115003
[Journal Article] Actin-binding protein ABP140 is a methyltransferase for 3-methylcytidine at position 32 of tRNAs in Saccharomyces cerevisiae2011
- Author(s)
  Akiko Noma, Sanghyun Yi, Takayuki Katoh, Yoshimi Takai, Takeo Suzuki, Tsutomu Suzuki
- Journal Title
  
  RNA
  
  Volume: 17 Pages: 1111-9
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21115003
[Journal Article] Molecular basis of dihydrouridine formation on tRNA2011
- Author(s)
  Futao Yu, Yoshikazu Tanaka, Keitaro Yamashita, Takeo Suzuki, Akiyoshi Nakamura, Nagisa Hirano, Tsutomu Suzuki, Min Yao, Isao Tanaka
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 108 Pages: 19593-8
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21115003
[Journal Article] Loss of ribosomal RNA modification causes developmental defects in zebrafish2011
- Author(s)
  Sayomi Higa-Nakamine, Takeo Suzuki, Tamayo Uechi, Anirban Chakraborty, Yukari Nakajima, Mikako Nakamura, Naoko Hirano, Tsutomu Suzuki, Naoya Kenmochi
- Journal Title
  
  Nucleic Acids Research.
  
  Volume: 40 Pages: 391-8
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21115003
[Journal Article] Human Mitochondrial tRNAs : Biogenesis, Function, Structural Aspects, and Diseases2011
- Author(s)
  Tsutomu Suzuki, Asuteka Nagao, Takeo Suzuki
- Journal Title
  
  Annu.Rev.Genet.
  
  Volume: 45 Pages: 299-329
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21115003
[Journal Article] Molecular basis of dihydrouridine formation on tRNA2011
- Author(s)
  Futao Yu, Yoshikazu Tanaka, Keitaro Yamashita, Takeo Suzuki, Akiyoshi Nakamura, Nagisa Hirano, Tsutomu Suzuki, Min Yao, Isao Tanaka
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 108 Pages: 19593-19598
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23710265
[Journal Article] Loss of ribosomal RNA modification causes developmental defects in zebrafish2011
- Author(s)
  Sayomi Higa-Nakamine, Takeo Suzuki, Tamayo Uechi, Anirban Chakraborty, Yukari Nakajima, Mikako Nakamura, Naoko Hirano, Tsutomu Suzuki and Naoya Kenmochi
- Journal Title
  
  Nucleic Acids Research.
  
  Volume: 40 Pages: 391-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23710265
[Journal Article] Deficit of Lys-tRNA Modification byCdkal1 Causes the Development of Type 2 Diabetes in Mice2011
- Author(s)
  Wei FY., Suzuki T., Watanabe S., Kimura S., Kaitsuka T., Fujimura A., Matsui H., Atta M., Michiue H., Fontecave M., Yamagata K., Suzuki T., Tomizawa K.
- Journal Title
  
  Journal of Clinical Investigation
  
  Volume: 121 Pages: 3598-3608
- DOI
  10.1172/jci58056
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J09964, KAKENHI-PLANNED-21115003, KAKENHI-PROJECT-21220010, KAKENHI-PROJECT-22227006, KAKENHI-PROJECT-22790214, KAKENHI-PUBLICLY-23112705, KAKENHI-PROJECT-23655153, KAKENHI-PROJECT-23710265
[Journal Article] Actin-binding protein ABP140 is a methyltransferase for 3-methylcytidine at position 32 of tRNAs in Saccharomyces cerevisiae2011
- Author(s)
  Akiko Noma, Sanghyun Yi, Takayuki Katoh, Yoshimi Takai, Takeo Suzuki and Tsutomu Suzuki
- Journal Title
  
  RNA
  
  Volume: 17 Pages: 1111-1119
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23710265
[Journal Article] Deficit of Lys-tRNA Modification by Cdkal1 Causes the Development of Type 2 Diabetes in Mice2011
- Author(s)
  FY Wei, T Suzuki, S Watanabe, S Kimura, T Kaitsuka, A Fujimura, H Matsui, M Atta, H Michiue, M Fontecave, K Yamagata, T Suzuki and K Tomizawa
- Journal Title
  
  J. Clin. Invest.
  
  Volume: 121 Pages: 3598-608
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23710265
[Journal Article] Human mitochondrial diseases caused by lack of taurine-modification in mitochondrial tRNAs2011
- Author(s)
  Suzuki T, Nagao A and Suzuki T
- Journal Title
  
  Wiley Interdiscip Rev RNA
  
  Volume: 2 Pages: 376-386
- DOI
  10.1002/wrna.65
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21115003, KAKENHI-PUBLICLY-23112705, KAKENHI-PROJECT-23655153, KAKENHI-PROJECT-23710265
[Journal Article] The silkworm W chromosome is a source of female-enriched piRNAs2011
- Author(s)
  Kawaoka S, Kadota K, Arai Y, Suzuki Y, Fujii T, Abe H, Yasukochi Y, Mita K, Sugano S, Shimizu K, Tomari Y, Shimada T, Katsuma S
- Journal Title
  
  RNA
  
  Volume: 17(12) Pages: 2144-2151
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-21115001
[Journal Article] Human Mitochondrial tRNAs: Biogenesis, Function, Structural Aspects, and Diseases2011
- Author(s)
  Suzuki T, Nagao A and Suzuki T
- Journal Title
  
  Annu Rev Genet.
  
  Volume: 45 Pages: 299-329
- DOI
  10.1146/annurev-genet-110410-132531
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21115003, KAKENHI-PROJECT-22227006, KAKENHI-PUBLICLY-23112705, KAKENHI-PROJECT-23710265
[Journal Article] Deficit of Lys-tRNA Modification by Cdkal1 Causes the Development of Type 2 Diabetes in Mice2011
- Author(s)
  FY Wei, T Suzuki, S Watanabe, S Kimura, T Kaitsuka, A Fujimura, H Matsui, M Atta, H Michiue, M Fontecave, K Yamagata, T Suzuki, K Tomizawa
- Journal Title
  
  J.Clin.Invest.
  
  Volume: 121 Pages: 3598-608
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21115003
[Journal Article] Zygotic amplification of secondary piRNAs during silkworm embryogenesis2011
- Author(s)
  Kawaoka S, Arai Y, Kadota K, Suzuki Y, Hara K, Sugano S, Shimizu K, Tomari Y, Shimada T, Katsuma S
- Journal Title
  
  RNA
  
  Volume: 17(7) Pages: 1401-1407
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-21115001
[Journal Article] Human mitochondrial diseases caused by lack of taurine-modification in mitochondrial tRNAs2011
- Author(s)
  Tsutomu Suzuki, Asuteka Nagao, Takeo Suzuki
- Journal Title
  
  WIREs RNA
  
  Volume: 121 Pages: 376-86
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21115003
[Journal Article] Taurine-containing uridine modifications in tRNA anticodons arerequired to decipher non-universal genetic codes in ascidian mitochondria.2011
- Author(s)
  Suzuki T (第1著者), 他8名
- Journal Title
  
  J.Biol. Chem
  
  Volume: 286 Pages: 35494-35498
- DOI
  10.1074/jbc.m111.279810
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21115003, KAKENHI-PROJECT-21570101, KAKENHI-PROJECT-21570242, KAKENHI-PROJECT-22227006, KAKENHI-PUBLICLY-23112705, KAKENHI-PROJECT-23655153, KAKENHI-PROJECT-23710265, KAKENHI-PROJECT-23770202
[Journal Article] Taurine-containing uridine modifications in tRNA anticodons are required to decipher non-universal genetic codes in ascidian mitochondria2011
- Author(s)
  Takeo Suzuki, Kenjyo Miyauchi, Tsutomu Suzuki, Shin-ichi Yokobori, Naoki Shigi, Akiko Kondow, Nono Takeuchi, Akihiko Yamagishi, and Kimitsuna Watanabe
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 286 Pages: 35494-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23710265
[Journal Article] Human mitochondrial diseases caused by lack of taurine-modification in mitochondrial tRNAs2011
- Author(s)
  Tsutomu Suzuki, Asuteka Nagao and Takeo Suzuki
- Journal Title
  
  WIREs RNA
  
  Volume: 2 Pages: 376-386
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23710265
[Journal Article] Agmatine-conjugated cytidine in tRNA anticodon essential for AUA decoding in archaea2010
- Author(s)
  Ikeuchi Y, Kimura S, Numata T, Nakamura D, Yokogawa T, Ogata T, Wada T, Suzuki T and Suzuki T
- Journal Title
  
  Nat. Chem. Biol
  
  Volume: 6 Pages: 277-282
- DOI
  10.1038/nchembio.323
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21115003
[Journal Article] Agmatine-conjugated cytidine in a tRNA anticodon is essential for AUA decoding in archaea2010
- Author(s)
  Ikeuchi Y, Kimura S, Numata T, Nakamura D, Yokogawa T, Ogata T, Wada T, Suzuki T, Suzuki T
- Journal Title
  
  Nat Chem Biol
  
  Volume: 6(4) Pages: 277-282
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-21115001
[Journal Article] ミトコンドリア脳筋症とtRNAのタウリン修飾欠損2010
- Author(s)
  鈴木勉、鈴木健夫
- Journal Title
  
  細胞工学
  
  Volume: 29 Pages: 137-143
- Data Source
  KAKENHI-PLANNED-21115003
[Journal Article] Hsc70/Hsp90 chaperone machinery mediates ATP-dependent RISC loading of small RNA duplexes2010
- Author(s)
  Iwasaki S, Kobayashi M, Yoda M, Sakaguchi Y, Katsuma S, Suzuki T, Tomari Y
- Journal Title
  
  Mol Cell
  
  Volume: 39(2) Pages: 292-299
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-21115001
[Presentation] ALKBH1 mediates 5-formylcytidine biogenesis in mammalian tRNAs2017
- Author(s)
  Layla Kawarada, Takeo Suzuki, Tsutomu Suzuki
- Organizer
  Conbio2017
- Data Source
  KAKENHI-PROJECT-26702035
[Presentation] Thermophilic archaeal tRNAs are stabilized by N4-acetylcyridine modification2017
- Author(s)
  Ohira, T., Chen, M., Kurihashi, T., Yamauchi, R., Ito, S., Kaneko, A., Orita, I., Fukui, T., Suzuki, T., Yao, M., Tanaka, Y., Suzuki, T.
- Organizer
  19th RNA meeting
- Data Source
  KAKENHI-PROJECT-26702035
[Presentation] Biogenesis and physiological role of 5-formylcytidine in mammalian mitochondrial tRNAMet2017
- Author(s)
  Takeo Suzuki, Layla Kawarada, Saori Nakano, Takayuki Ohira, Hiroyoshi Iwata, Kana Asano, Shoji Hirata, Kenjyo Miyauchi, Tsutomu Suzuki
- Organizer
  19th RNA meeting
- Data Source
  KAKENHI-PROJECT-26702035
[Presentation] RNA-MSを用いたトリパノソーマmRNAおよびSL RNAにおける転写後修飾の解析2017
- Author(s)
  穐近慎一郎、松木美知枝、鈴木健夫、Ho Kiong、鈴木勉
- Organizer
  第17回東京大学生命科学シンポジウム
- Data Source
  KAKENHI-PROJECT-26702035
[Presentation] ALKBH1はミトコンドリアおよび細胞質tRNA修飾のジオキシゲナーゼとしてはたらく2017
- Author(s)
  川原田礼以良、鈴木健夫、大平高之、平田翔児、宮内健常、鈴木勉
- Organizer
  第17回東京大学生命科学シンポジウム
- Data Source
  KAKENHI-PROJECT-26702035
[Presentation] 哺乳類ミトコンドリアtRNAに存在する5-メチルシチジンの機能解析2017
- Author(s)
  北川翔、中野沙緒里、中川真一、荒木喜美、荒木正健、鈴木健夫、鈴木勉
- Organizer
  第17回東京大学生命科学シンポジウム
- Data Source
  KAKENHI-PROJECT-26702035
[Presentation] Biogenesis and function of N6-methyladenosine in U snRNAs2016
- Author(s)
  Ishigami, Y., Ohira, T., Akichika, S., Suzuki, T., Suzuki, T.
- Organizer
  RNA2016
- Place of Presentation
  Kyoto International Conference Center, Kyoto, Japan
- Year and Date
  2016-06-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26702035
[Presentation] Mass spectrometric characterization of post-transcriptional modifications in mRNAs and spliced-leader RNA from Trypanosoma brucei2016
- Author(s)
  Akichika, S., Matsuki, M., Suzuki, T., Ho, C. K., Suzuki, T.
- Organizer
  MBSJ2016
- Place of Presentation
  Pacifico Yokohama, Kanagawa, Japan
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26702035
[Presentation] Functional analysis of 5-methylcytidine in mammalian mitochondrial tRNA2016
- Author(s)
  Kitagawa, S., Nakano, S., Nakagawa, S., Suzuki, T., Araki, K., Araki, M., Suzuki, T.
- Organizer
  MBSJ2016
- Place of Presentation
  Pacifico Yokohama, Kanagawa, Japan
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26702035
[Presentation] Substrate recognition by NSUN3, an RNA methyltransferase which initiates 5-formylcytidine formation in human mitochondrial tRNAMet2016
- Author(s)
  In, S., Kawarada, L., Suzuki, T., Suzuki, T.
- Organizer
  MBSJ2016
- Place of Presentation
  Pacifico Yokohama, Kanagawa, Japan
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26702035
[Presentation] NSUN3 initiates formation of 5-formylcytidine, a post-transcriptional modification in human mitochondrial tRNAMet required to decipher non-universal genetic code2016
- Author(s)
  Nakano, S., Suzuki, T., Kawarada, L., Iwata, H., Asano, K., Suzuki, T.
- Organizer
  RNA2016
- Place of Presentation
  Kyoto International Conference Center, Kyoto, Japan
- Year and Date
  2016-06-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26702035
[Presentation] A complete landscape of post-transcriptional modifications in human mitochondrial tRNAs2016
- Author(s)
  Suzuki, T., Yashiro, Y., Asano, K., Lin, H., Kirino, Y., Sakaguchi, Y., Suzuki, T.
- Organizer
  RNA2016
- Place of Presentation
  Kyoto International Conference Center, Kyoto, Japan
- Year and Date
  2016-06-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26702035
[Presentation] Deficiency of tRNA modification causes the development of X-linked mental retardation2015
- Author(s)
  Fan-Yan Wei, Yu Nagayoshi, Shoji Hirata, Takeo Suzuki, Tsutomu Suzuki, Kazuhito Tomizawa
- Organizer
  第17回日本RNA学会年会
- Place of Presentation
  ホテルライフォート札幌、札幌市、北海道
- Year and Date
  2015-07-15
- Data Source
  KAKENHI-PROJECT-26702035
[Presentation] Biogenesis of 5-taurinomethyluridine in human mitochondrial tRNAs; implication for molecular pathogenesis of mitochondrial diseases2015
- Author(s)
  Kana Asano, Takeo Suzuki, Fan-Yan Wei, Yoshiho Ikeuchi, Yuka Yashiro, Christin Tischner, Annette Hofer, Yoshihito Kishita, Yasushi Okazaki, Tina Wenz, Kazuhito Tomizawa, Tsutomu Suzuki
- Organizer
  第17回日本RNA学会年会
- Place of Presentation
  ホテルライフォート札幌、札幌市、北海道
- Year and Date
  2015-07-15
- Data Source
  KAKENHI-PROJECT-26702035
[Presentation] Exploration and functional analysis of queuosine-glycosyltransferases in mammals2015
- Author(s)
  Xuewei Zhao, Takeo Suzuki, Tsutomu Suzuki
- Organizer
  第17回日本RNA学会年会
- Place of Presentation
  ホテルライフォート札幌、札幌市、北海道
- Year and Date
  2015-07-15
- Data Source
  KAKENHI-PROJECT-26702035
[Presentation] Exploration and functional analysis of queuosine- glycosyltransferases in mammals2015
- Author(s)
  Xuewei Zhao, Takeo Suzuki, Tsutomu Suzuki
- Organizer
  第17回日本RNA学会年会
- Place of Presentation
  ホテルライフォート札幌, 札幌市, 北海道
- Year and Date
  2015-07-15
- Data Source
  KAKENHI-PROJECT-26560442
[Presentation] Deficiency of tRNA modification causes the development of X-linked mental retardation2015
- Author(s)
  Fan-Yan Wei, Yu Nagayoshi, Shoji Hirata, Takeo Suzuki, Tsutomu Suzuki, Kazuhito Tomizawa
- Organizer
  第17回日本RNA学会年会
- Place of Presentation
  ホテルライフォート札幌, 札幌市, 北海道
- Year and Date
  2015-07-15
- Data Source
  KAKENHI-PROJECT-26560442
[Presentation] Biogenesis of 5-taurinomethyluridine in human mitochondrial tRNAs; implication for molecular pathogenesis of mitochondrial diseases2015
- Author(s)
  Kana Asano, Takeo Suzuki, Fan-Yan Wei, Yoshiho Ikeuchi, Yuka Yashiro, Christin Tischner, Annette Hofer, Yoshihito Kishita, Yasushi Okazaki, Tina Wenz, Kazuhito Tomizawa, Tsutomu Suzuki
- Organizer
  第17回日本RNA学会年会
- Place of Presentation
  ホテルライフォート札幌, 札幌市, 北海道
- Year and Date
  2015-07-15
- Data Source
  KAKENHI-PROJECT-26560442
[Presentation] U snRNAにおけるN6-メチルアデノシン修飾の生合成と機能解析2015
- Author(s)
  石神宥真、大平高之、穐近慎一郎、鈴木健夫、鈴木勉
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド、神戸市、兵庫県
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26702035
[Presentation] U snRNAにおけるN6-メチルアデノシン修飾の生合成と機能解析2015
- Author(s)
  石神宥真、大平高之、穐近慎一郎、鈴木健夫、鈴木勉
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド, 神戸市, 兵庫県
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26560442
[Presentation] Sensitive measurement of tRNA 2-methylthio modification by quantitative PCR for clinical assessment of type 2 diabetes risk2013
- Author(s)
  Fan-Yan Wei, Peiyu Xie, Shoji Hirata, Taku Kaitsuka, Tsutomu Suzuki, Kazuhito Tomizawa, Takeo Suzuki
- Organizer
  15th RNA meeting
- Place of Presentation
  Himegin Hall, Ehime
- Data Source
  KAKENHI-PLANNED-21115003
[Presentation] Molecular pathogenesis of non-syndromic X-linked intellectual disability caused by a loss-of-function mutation in FTSJ12013
- Author(s)
  Shoji Hirata, Takeo Suzuki, Kenjyo Miyauchi, Yuichi Goto, Tsutomu Suzuki
- Organizer
  MBSJ2013
- Place of Presentation
  Kobe Port Island, Hyogo
- Data Source
  KAKENHI-PLANNED-21115003
[Presentation] Novel modified nucleoside found in 16S rRNA from halophilic archaea2013
- Author(s)
  Takeo Suzuki, Hajime Takeda, Tomoyuki Watanabe, Naoki Uchiyama, Takeshi Wada, Tsutomu Suzuki
- Organizer
  MBSJ2013
- Place of Presentation
  Kobe, Japan
- Data Source
  KAKENHI-PLANNED-21115003
[Presentation] Mechanistic insights into the functional role of the RlmE-mediated Um2552 formation in the late assembly of 50S subunit in Escherichia coli2013
- Author(s)
  Taiga Arai, Satoshi Kimura, Yuriko Sakaguchi, Takeo Suzuki and Tsutomu Suzuki
- Organizer
  15th RNA meeting
- Place of Presentation
  Himegin Hall, Ehime
- Data Source
  KAKENHI-PLANNED-21115003
[Presentation] Functional analysis of a 2?-5 ?RNA ligase from the Hyperthermophilc archaeon Thermococcus kodakarensis2013
- Author(s)
  Akira Hirata, Tomoko Nagano, Yuki Ishimaru, Tamotsu Kanai, Takeo Suzuki, Asako Sato, Akio Kanai, Tsutomu Suzuki, Hori Hiroyuki
- Organizer
  15th RNA meeting
- Place of Presentation
  Himegin Hall, Ehime
- Data Source
  KAKENHI-PLANNED-21115003
[Presentation] Alternative pathway of tRNA maturation in Saccharomyces cerevisiae2012
- Author(s)
  Takayuki Ohira, Kenjyo Miyauchi, Yuriko Sakaguchi, Takeo Suzuki, Tsutomu Suzuki
- Organizer
  The 24th tRNA conference
- Place of Presentation
  Olmue, Chile
- Year and Date
  2012-12-02
- Data Source
  KAKENHI-PLANNED-21115003
[Presentation] The acetylation of 18S rRNA is an essential modification to synthesize the small subunit of ribosome in Saccharomyces cerevisiae2012
- Author(s)
  Satoshi Ito, Yu Akamatsu, Akiko Noma, Satoshi Kimura, Yoshiho Ikeuchi, Kenjyo Miyauchi, Yoshikazu Tanaka, Isao Tanaka, Takeo Suzuki, Tsutomu Suzuki
- Organizer
  The 9th International Conference on Ribosome Synthesis
- Place of Presentation
  Banff, Canada
- Year and Date
  2012-08-22
- Data Source
  KAKENHI-PLANNED-21115003
[Presentation] Insights into the functional role of the RlmE-mediated Um2552 formation in the late assembly of 50S subunit in Escherichia coli2012
- Author(s)
  Taiga Arai, Satoshi Kimura, Yuriko Sakaguchi, Takeo Suzuki, Tsutomu Suzuki
- Organizer
  The 9th International Conference on Ribosome Synthesis
- Place of Presentation
  Banff, Canada
- Year and Date
  2012-08-20
- Data Source
  KAKENHI-PLANNED-21115003
[Presentation] Native chemical structures of Escherichia coli tRNAs determined by mass spectrometric analysis2011
- Author(s)
  Kenjyo Miyauchi, Satoshi Kimura, Yuriko Sakaguchi, Takeo Suzuki, Tsutomu Suzuki
- Organizer
  MBSJ2011
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PLANNED-21115003
[Presentation] Biochemical characterization of 40S intermediate in the assembly of 50S ribosomal subunit in Escherichia coli2011
- Author(s)
  Taiga Arai, Satishi Kimura, Yuriko Sakaguchi, Takeo Suzuki, Tsutomu Suzuki
- Organizer
  MBSJ2011
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PLANNED-21115003
[Presentation] Crystal structure of dihydrouridine synthase in complex with RNA reveals its tRNA recognition and reaction mechanisms2011
- Author(s)
  Yoshikazu Tanaka, Futao Yu, Keitaro Yamashita, Akiyoshi Nakamura, Takeo Suzuki, Nagisa Hirano, Tsutomu Suzuki, Min Yao, Isao Tanaka
- Organizer
  RNA2011Kyoto
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-23710265
[Presentation] The acetylation of 18S rRNA is an essential modification to synthesize the small subunit of ribosome in Saccharomyces cerevisiae2011
- Author(s)
  Satoshi Ito, Yu Akamatsu, Akiko Noma, Satoshi Kimura, Yoshiho Ikeuchi, Keniyo Miyauchi, Yoshikazu Tanaka, Isao Tanaka, Takeo Suzuki, Tsutomu Suzuki
- Organizer
  MBSJ2011
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PLANNED-21115003
[Presentation] Base Methylations in the Double-stranded RNA by a Fused Methyltransferase Bearing Unwinding Activity2011
- Author(s)
  Satoshi Kimura, Yoshiho Ikeuchi, Kei Kitahara, Yuriko Sakaguchi, Takeo Suzuki, Tsutomu Suzuki
- Organizer
  RNA2011Kyoto
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-23710265
[Presentation] Unique characteristics of ascidian mitochondrial tRNAs : Existence of 5-t aurinomethyluridine-containing tRNAs involved in deciphering the non-universal genetic codes and an initiator tRNA corresponding to AUG codon2011
- Author(s)
  Takeo Suzuki, Kenjyo Miyauchi, Shin-ichi Yokobori, Naoki Shigi, Akiko Kondow, Nono Takeuchi, Tsutomu Suzuki, Akihiko Yamagishi, Kimitsuna Watanabe
- Organizer
  RNA2011Kyoto
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PLANNED-21115003
[Presentation] Unique characteristics of ascidian mitochondrial tRNAs: Existence of 5-taurinomethyluridine-containing tRNAs involved in deciphering the non-universal genetic codes and an initiator tRNA corresponding to AUG codon2011
- Author(s)
  Takeo Suzuki, Kenjyo Miyauchi, Shin-ichi Yokobori, Naoki Shigi, Akiko Kondow, Nono Takeuchi, Tsutomu Suzuki, Akihiko Yamagishi, Kimitsuna Watanabe
- Organizer
  RNA2011Kyoto
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-23710265
[Presentation] Necessity of tRNA introns for yeast growth2011
- Author(s)
  Shunsuke Mori, Toshiya Endo, Takeo Suzuki, Tsutomu Suzuki, Tohru Yoshihisa
- Organizer
  RNA2011Kyoto
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PLANNED-21115003
[Presentation] Necessity of tRNA introns for yeast growth2011
- Author(s)
  Shunsuke Mori, Toshiya Endo, Takeo Suzuki, Tsutomu Suzuki, Tohru Yoshihisa
- Organizer
  RNA2011Kyoto
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-23710265
[Presentation] Characterization of Human Homologues of MnmE and GidA, Required for an xm5U-type Uridine Modification at the Wobble Position of Mitochondrial tRNAs2011
- Author(s)
  Takeo Suzuki et al
- Organizer
  RNA2011Kyoto
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-23710265
[Presentation] In Vivo Reversal of a UV-induced Lesion on Mouse 28S rRNA2011
- Author(s)
  Atsumi Miyata, Makoto Kitabatake, Takeo Suzuki, Tsutomu Suzuki, Tomoko Sakata, Yohei Kobayashi, Shin Yonehara, Mutsuhito Ohno
- Organizer
  RNA2011Kyoto
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-23710265
[Presentation] Characterization of Human Homologues of MnmE and GidA, Required for an xm5U-type Uridine Modification at the Wobble Position of Mitochondrial tRNAs2011
- Author(s)
  Takeo Suzuki, Hirosi Sakai, Tomoyuki Numata, Takuo Osawa, Tsutomu Suzuki
- Organizer
  RNA2011Kyoto
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PLANNED-21115003
[Presentation] Native chemical structures of Escherichia coli tRNAs determined by mass spectrometric analysis2011
- Author(s)
  Kenjyo Miyauchi，Satoshi Kimura，Yuriko Sakaguchi，Takeo Suzuki，Tsutomu Suzuki
- Organizer
  MBSJ2011
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-23710265
[Presentation] The third pathway of tRNA export requires the retrograde import of precursor tRNA from cytoplasm to nucleus for its maturation in Saccharomyces cerevisiae2011
- Author(s)
  Takayuki Ohira，Kenjyo Miyauchi，Yuriko Sakaguchi，Takeo Suzuki，Tsutomu Suzuki
- Organizer
  MBSJ2011
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-23710265
[Presentation] The third pathway of tRNA export requires the retrograde import of precursor tRNA from cytoplasm to nucleus for its maturation in Saccharomyces cerevisiae2011
- Author(s)
  Takayuki Ohira, Keniyo Miyauchi, Yuriko Sakaguchi, Takeo Suzuki, Tsutomu Suzuki
- Organizer
  MBSJ2011
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PLANNED-21115003
[Presentation] In Vivo Reversal of a UV-induced Lesion on Mouse 28S rRNA2011
- Author(s)
  Atsumi Miyata, Makoto Kitabatake, Takeo Suzuki, Tsutomu Suzuki, Tomoko Sakata, Yohei Kobayashi, Shin Yonehara, Mutsuhito Ohno
- Organizer
  RNA2011Kyoto
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PLANNED-21115003
[Presentation] Base methylations in the double-stranded RNA by a fused methyltransferase bearing unwinding activity in ribosome assembly2011
- Author(s)
  Satoshi Kimura，Yoshiho Ikeuchi，Kei Kitahara，Yuriko Sakaguchi，Takeo Suzuki，Tsutomu Suzuki
- Organizer
  MBSJ2011
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-23710265
[Presentation] Crystal structure of dihydrouridine synthase in complex with RNA reveals its tRNA recognition and reaction mechanisms2011
- Author(s)
  Yoshikazu Tanaka, Futao Yu, Keitaro Yamashita, Akiyoshi Nakamura, Takeo Suzuki, Nagisa Hirano, Tsutomu Suzuki, Min Yao, Isao Tanaka
- Organizer
  RNA2011Kyoto
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PLANNED-21115003
[Presentation] Base methylations in the double-stranded RNA by a fused methyltransferase bearing unwinding activity in ribosome assembly2011
- Author(s)
  Satoshi Kimura, Yoshiho Ikeuchi, Kei Kitahara, Yuriko Sakaguchi, Takeo Suzuki, Tsutomu Suzuki
- Organizer
  MBSJ2011
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PLANNED-21115003
[Presentation] Base Methylations in the Double-stranded RNA by a Fused Methyltransferase Bearing Unwinding Activity2011
- Author(s)
  Satoshi Kimura, Yoshiho Ikeuchi, Kei Kitahara, Yuriko Sakaguchi, Takeo Suzuki, Tsutomu Suzuki
- Organizer
  RNA2011Kyoto
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PLANNED-21115003
[Presentation] Biochemical characterization of 40S intermediate in the assembly of 50S ribosomal subunit in Escherichia coli2011
- Author(s)
  Taiga Arai, Satishi Kimura, Yuriko Sakaguchi, Takeo Suzuki and Tsutomu Suzuki
- Organizer
  MBSJ2011
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-23710265
[Presentation] The acetylation of 18S rRNA is an essential modification to synthesize the small subunit of ribosome in Saccharomyces cerevisiae2011
- Author(s)
  Satoshi Ito，Yu Akamatsu，Akiko Noma，Satoshi Kimura，Yoshiho Ikeuchi，Kenjyo Miyauchi，Yoshikazu Tanaka，Isao Tanaka，Takeo Suzuki，Tsutomu Suzuki
- Organizer
  MBSJ2011
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-23710265
[Presentation] Requirements for in vitro formation of 5-carboxymethylaminometyluri dine at the wobble position in Escherichia coli tRNAs2010
- Author(s)
  Suzuki, T., et al.
- Organizer
  23rd tRNA workshop
- Place of Presentation
  Aveiro, Portugal
- Data Source
  KAKENHI-PLANNED-21115003
[Presentation] Biosynthetic mechanism and substrate recognition by modification enzymes of the wobble xm5-modified uridine in Escherichia coli2010
- Author(s)
  Suzuki, T., et al.
- Organizer
  BMB2010
- Place of Presentation
  Kobe, Japan
- Data Source
  KAKENHI-PLANNED-21115003
[Presentation] Requirements for in vitro formation of 5-carboxymethylaminometyluridine at the wobble position in Escherichia coli tRNAs2009
- Author(s)
  Suzuki, T., et al.
- Organizer
  32nd MBSJ
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PLANNED-21115003
[Presentation] Analysis of the functional role of FTSJ1 related to non-syndromic X-linked intellectual disability
- Author(s)
  Shoji Hirata, Takeshi Chujo, Takeo Suzuki, Kenjyo Miyauchi, Yuichi Goto, Tsutomu Suzuki
- Organizer
  第16回日本RNA学会年会
- Place of Presentation
  ウインクあいち、名古屋市、愛知県
- Year and Date
  2014-07-23 – 2014-07-25
- Data Source
  KAKENHI-PROJECT-26702035
[Presentation] Analysis of the functional role of FTSJ1 related to non-syndromic X-linked intellectual disability
- Author(s)
  Shoji Hirata, Takeshi Chujo, Takeo Suzuki, Kenjyo Miyauchi, Yuichi Goto, Tsutomu Suzuki
- Organizer
  第16回日本RNA学会年会
- Place of Presentation
  ウインクあいち、名古屋市、愛知県
- Year and Date
  2014-07-23 – 2014-07-25
- Data Source
  KAKENHI-PROJECT-26560442
[Presentation] ミトコンドリアtRNAタウリン修飾の生合成と機能
- Author(s)
  鈴木健夫、浅野奏、魏范研、富澤一仁、池内与志穂、鈴木勉
- Organizer
  第14回日本ミトコンドリア学会年会
- Place of Presentation
  九大医百年講堂、福岡市、福岡県
- Year and Date
  2014-12-03 – 2014-12-05
- Data Source
  KAKENHI-PROJECT-26702035
[Presentation] Alternative pathway of tRNA maturation in Saccharomyces cerevisiae
- Author(s)
  Takayuki Ohira, Kenjyo Miyauchi, Yuriko Sakaguchi, Takeo Suzuki, Tsutomu Suzuki
- Organizer
  The 24th tRNA conference
- Place of Presentation
  Olmue, Chile
- Data Source
  KAKENHI-PROJECT-23710265
[Presentation] A complete landscape of post-transcriptional modifications in mammalian mitochondrial tRNAs
- Author(s)
  Suzuki, T. and Suzuki, T.
- Organizer
  The 25th tRNA conference
- Place of Presentation
  Kyllini, Greece
- Year and Date
  2014-09-21 – 2014-09-25
- Data Source
  KAKENHI-PROJECT-26702035
[Presentation] ミトコンドリアtRNAタウリン修飾の生合成と機能
- Author(s)
  鈴木健夫、浅野奏、魏范研、富澤一仁、池内与志穂、鈴木勉
- Organizer
  第14回日本ミトコンドリア学会年会
- Place of Presentation
  九大医百年講堂、福岡市、福岡県
- Year and Date
  2014-12-03 – 2014-12-05
- Data Source
  KAKENHI-PROJECT-26560442
[Presentation] 哺乳類ミトコンドリアにおけるtRNA48位の5-メチルシチジン修飾酵素の同定
- Author(s)
  中野紗緒里、鈴木健夫、荒木喜美、荒木正健、鈴木勉
- Organizer
  第14回日本ミトコンドリア学会年会
- Place of Presentation
  九大医百年講堂、福岡市、福岡県
- Year and Date
  2014-12-03 – 2014-12-05
- Data Source
  KAKENHI-PROJECT-26560442
[Presentation] The acetylation of 18S rRNA is an essential modification to synthesize the small subunit of ribosome in Saccharomyces cerevisiae
- Author(s)
  Satoshi Ito, Yu Akamatsu, Akiko Noma, Satoshi Kimura, Yoshiho Ikeuchi, Kenjyo Miyauchi, Yoshikazu Tanaka, Isao Tanaka, Takeo Suzuki, Tsutomu Suzuki
- Organizer
  The 9th International Conference on Ribosome Synthesis
- Place of Presentation
  Banff, Canada
- Data Source
  KAKENHI-PROJECT-23710265
[Presentation] 哺乳類ミトコンドリアにおけるtRNA48位の5-メチルシチジン修飾酵素の同定
- Author(s)
  中野紗緒里、鈴木健夫、荒木喜美、荒木正健、鈴木勉
- Organizer
  第14回日本ミトコンドリア学会年会
- Place of Presentation
  九大医百年講堂、福岡市、福岡県
- Year and Date
  2014-12-03 – 2014-12-05
- Data Source
  KAKENHI-PROJECT-26702035
[Presentation] Mitochondrial disease as the first instance of RNA modopathy
- Author(s)
  Takeo Suzuki, Kana Asano, Fan-Yan Wei, Kazuhito Tomizawa, Tsutomu Suzuki
- Organizer
  第16回日本RNA学会年会
- Place of Presentation
  ウインクあいち、名古屋市、愛知県
- Year and Date
  2014-07-23 – 2014-07-25
- Invited
- Data Source
  KAKENHI-PROJECT-26702035
[Presentation] Mitochondrial disease as the first instance of RNA modopathy
- Author(s)
  Takeo Suzuki, Kana Asano, Fan-Yan Wei, Kazuhito Tomizawa, Tsutomu Suzuki
- Organizer
  第16回日本RNA学会年会
- Place of Presentation
  ウインクあいち、名古屋市、愛知県
- Year and Date
  2014-07-23 – 2014-07-25
- Invited
- Data Source
  KAKENHI-PROJECT-26560442
[Presentation] Insights into the functional role of the RlmE-mediated Um2552 formation in the late assembly of 50S subunit in Escherichia coli
- Author(s)
  Taiga Arai, Satoshi Kimura, Yuriko Sakaguchi, Takeo Suzuki, Tsutomu Suzuki
- Organizer
  The 9th International Conference on Ribosome Synthesis
- Place of Presentation
  Banff, Canada
- Data Source
  KAKENHI-PROJECT-23710265
[Presentation] A complete landscape of post-transcriptional modifications in mammalian mitochondrial tRNAs
- Author(s)
  Suzuki, T. and Suzuki, T.
- Organizer
  The 25th tRNA conference
- Place of Presentation
  Kyllini, Greece
- Year and Date
  2014-09-21 – 2014-09-25
- Data Source
  KAKENHI-PROJECT-26560442

1. TOMARI Yukihide (90447368)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
2. KAGEYAMA Yuji (90335480)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. TEI Kumiko (50213327)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. NAKAZAWA Takanobu (00447335)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. WADA Takeshi (90240548)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. SADO Takashi (70321601)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. SIOMI Mikiko (20322745)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. MIYAGAWA Satomi (90291153)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. NAKAGAWA Shinichi (50324679)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. TAKESHITA Fumitaka (40466199)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. ODA Takeaki (00608523)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
12. YAMASHITA Akio (20405020)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. NISHIMURA Yukiko (30514567)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. TAKEMOTO Chi (40306527)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. Mohri Satoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
16. SATO Yasufumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. INO Yasushi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. TODO Tomoki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. SAITO Kuniaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. WEI Fanyan

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
21. SUZUKI Tsutomu

# of Collaborated Projects: 0 results

# of Collaborated Products: 25 results
22. KENMOCHI Naoya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. YOKOBORI Shin-ichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
24. WATANABE Kimitsuna

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
25. SHIGI Naoki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 富澤一仁

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
27. 荒木喜美

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
28. 松井秀樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 道上宏之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 尾池雄一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 氏原嘉洋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. 秋山徹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. 那須亮

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. 武笠晃丈

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. 荒木正健

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. 藤村篤史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
37. 田中良和

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
38. 仲嶺三代美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SUZUKI Takeo 鈴木 健夫

Research Projects

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希少なRNA修飾の機能究明と動的調節機構の提唱Principal InvestigatorOngoing

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Research for an mRNA modication specific to vertebratesPrincipal InvestigatorOngoing

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Exploring RNA modifications using enzymatic probe and its applicationsPrincipal Investigator

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Biosynthesis and function of characteristic RNA modifications found in humanPrincipal Investigator

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Biosynthetic mechanism of the wobble modified uridines in tRNAPrincipal Investigator

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Structural bases for an expanded codon recognition by modified nucleotide.

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Functional machinery for non-coding RNAs

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Structural and functional analysis of non-coding RNA machineriesPrincipal Investigator

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[Journal Article] Defective mitochondrial tRNA taurine modification activates global protcostress and leads to mitochondrial disease.2018

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[Journal Article] Metabolic and chemical regulation of tRNA modification associated with taurine deficiency and human disease2018

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[Journal Article] Identification of 2-methylthio cyclic N6-threonylcarbamoyladenosine (ms2ct6A) as a novel RNA modification at position 37 of tRNAs2017

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[Journal Article] ALKBH1 is an RNA dioxygenase responsible for cytoplasmic and mitochondrial tRNA modifications2017

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[Journal Article] Mtu1-mediated thiouridine formation of mitochondrial tRNAs is required for mitochondrial translation and is involved in reversible infantile liver2016

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[Journal Article] NSUN3 methylase initiates 5-formylcytidine biogenesis in human mitochondrial tRNAMet2016

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SUZUKI Takeo 鈴木健夫