SUZUKI Takeo 鈴木健夫

Researcher Number	90533125
Other IDs
Affiliation (Current)	2025: 琉球大学, 医学(系)研究科(研究院), 教授
Affiliation (based on the past Project Information) *help	2022 – 2025: 琉球大学, 医学(系)研究科(研究院), 教授 2022: 琉球大学, 医学研究科, 教授 2017 – 2021: 東京大学, 大学院工学系研究科(工学部), 講師 2011 – 2016: 東京大学, 工学(系)研究科(研究院), 講師 2013: 東京大学, 大学院工学系研究科, 講師 … More 2012: 東京大学, 工学(系)研究科(研究院), 助教 2011 – 2012: 東京大学, 大学院・工学系研究科, 講師 2009 – 2010: 東京大学, 大学院・工学系研究科, 助教 2009: 東京大学, 工学(系)研究科, 助教 Less
Review Section/Research Field	Principal Investigator Basic Section 37020:Chemistry and chemical methodology of biomolecules-related / Medium-sized Section 37:Biomolecular chemistry and related fields / Basic Section 43030:Functional biochemistry-related / Biomolecular chemistry / Chemical biology / Chemical biology / Biological Sciences Except Principal Investigator Basic Section 64040:Social-ecological systems-related / Transformative Research Areas, Section (III) / Living organism molecular science / Biological Sciences
Keywords	Principal Investigator RNA修飾 / 生合成 / tRNA / RNA / 修飾 / ミトコンドリア / メチル化 / 修飾酵素 / 転写後修飾 / デコーディング … More / LC/MS / 発現制御 / 転移反応 / 代謝 / 疾患 / 遺伝暗号解読 / 点変異 / アンチコドン / 遺伝子発現 / 脊椎動物 / mRNA / 酵素 / ｔRNA / 遺伝子 / 化学修飾 / 化学標識 / 網羅的探索 / 特異的標識 / ウリジン / ウォブル位 / 細胞内化学反応 / キャップ構造 / 質量分析 / 末端構造 / 非コードRNA / プロセシング … More Except Principal Investigator 化学物質 / カダヤシ / 外来魚 / 質量分析 / タンパク質合成 / tRA Ile2 / 結晶構造解析 / Lysidine / コドン認識 / 修飾塩基 / tRNA / 超分子複合 / X線結晶構造解析 / リボソーム / ゲノム / 蛋白質 / 核酸 / 発現制御 / 遺伝子 Less

哺乳類に固有なRNA修飾因子による組織特異的な機能発現メカニズムの探求Principal Investigator
- Principal Investigator
  
  鈴木健夫
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  University of the Ryukyus
外来魚が水中に放出する化学物質が在来生態系を崩壊させる: 新仮説検証と物質同定
- Principal Investigator
  
  佐藤香織 (鶴井香織)
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 64040:Social-ecological systems-related
- Research Institution
  University of the Ryukyus
ヒトに特有な希少RNA修飾の分子・生理機能の探求Principal Investigator
- Principal Investigator
  
  鈴木健夫
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 37020:Chemistry and chemical methodology of biomolecules-related
- Research Institution
  University of the Ryukyus
Mechanistic elucidation of non-domain type biopolymer modifications
- Principal Investigator
  
  尾山大明
- Project Period (FY)
  2021 – 2025
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  The University of Tokyo
Biosynthesis and function of a novel tRNA modification ectopically acquired by a disease associated mutationPrincipal Investigator
- Principal Investigator
  
  Suzuki Takeo
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 37:Biomolecular chemistry and related fields
- Research Institution
  The University of Tokyo
Research for an mRNA modication specific to vertebratesPrincipal Investigator
- Principal Investigator
  
  Suzuki Takeo
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 37:Biomolecular chemistry and related fields
- Research Institution
  The University of Tokyo
Function and dynamic regulation of animal specific RNA modificationsPrincipal Investigator
- Principal Investigator
  
  Suzuki Takeo
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 37020:Chemistry and chemical methodology of biomolecules-related
- Research Institution
  The University of Tokyo
Exploring RNA modifications using enzymatic probe and its applicationsPrincipal Investigator
- Principal Investigator
  
  Suzuki Takeo
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Chemical biology
- Research Institution
  The University of Tokyo
Biosynthesis and function of characteristic RNA modifications found in humanPrincipal Investigator
- Principal Investigator
  
  Suzuki Takeo
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Biomolecular chemistry
- Research Institution
  The University of Tokyo
Biosynthetic mechanism of the wobble modified uridines in tRNAPrincipal Investigator
- Principal Investigator
  
  SUZUKI Takeo
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Chemical biology
- Research Institution
  The University of Tokyo
Structural bases for an expanded codon recognition by modified nucleotide.
- Principal Investigator
  
  TAKEMOTO Chi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Living organism molecular science
- Research Institution
  The Institute of Physical and Chemical Research
Functional machinery for non-coding RNAs
- Principal Investigator
  
  TOMARI Yukihide
- Project Period (FY)
  2009 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Structural and functional analysis of non-coding RNA machineriesPrincipal Investigator
- Principal Investigator
  
  SUZUKI Takeo
- Project Period (FY)
  2009 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo

[Book] ミトコンドリアRNA修飾異常による疾患と治療2023
- Author(s)
  鈴木勉、友田愛奈、鈴木健夫、長尾翌手可
- Total Pages
  7
- Publisher
  実験医学増刊 Vol.41 No.5 ミトコンドリア疾患治療の新時代
- Data Source
  KAKENHI-PLANNED-21H05280
[Journal Article] Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth2023
- Author(s)
  Zhao Xuewei、Ma Ding、Ishiguro Kensuke、Saito Hironori、Akichika Shinichiro、Matsuzawa Ikuya、Mito Mari、Irie Toru、Ishibashi Kota、Wakabayashi Kimi、Sakaguchi Yuriko、Yokoyama Takeshi、Mishima Yuichiro、Shirouzu Mikako、Iwasaki Shintaro、Suzuki Takeo、Suzuki Tsutomu
- Journal Title
  
  Cell
  
  Volume: 186 Issue: 25 Pages: 5517-5535.e24
- DOI
  10.1016/j.cell.2023.10.026
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23KK0105, KAKENHI-PROJECT-18H05272, KAKENHI-PLANNED-21H05280, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-23K23475
[Journal Article] 4.5SH RNA counteracts deleterious exonization of SINE B1 in mice2023
- Author(s)
  Yoshimoto Rei、Nakayama Yuta、Nomura Ikuko、Yamamoto Ikuko、Nakagawa Yumeka、Tanaka Shigeyuki、Kurihara Misuzu、Suzuki Yu、Kobayashi Takehiko、Kozuka-Hata Hiroko、Oyama Masaaki、Mito Mari、Iwasaki Shintaro、Yamazaki Tomohiro、Hirose Tetsuro、Araki Kimi、Nakagawa Shinichi
- Journal Title
  
  Molecular Cell
  
  Volume: 83 Issue: 24 Pages: 4479-4493
- DOI
  10.1016/j.molcel.2023.11.019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K24688, KAKENHI-PROJECT-22K05565, KAKENHI-ORGANIZER-21H05273, KAKENHI-PLANNED-21H05274, KAKENHI-PLANNED-21H05276, KAKENHI-PLANNED-21H05280, KAKENHI-PUBLICLY-23H04258, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-23K21285, KAKENHI-PROJECT-23K23809, KAKENHI-PROJECT-23K26910
[Journal Article] Restoration of mitochondrial function through activation of hypomodified tRNAs with pathogenic mutations associated with mitochondrial diseases2023
- Author(s)
  Tomoda Ena、Nagao Asuteka、Shirai Yuki、Asano Kana、Suzuki Takeo、Battersby Brendan J、Suzuki Tsutomu
- Journal Title
  
  Nucleic Acids Research
  
  Volume: in press Issue: 14 Pages: 7563-7579
- DOI
  10.1093/nar/gkad139
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-21H05280, KAKENHI-PROJECT-23K23475, KAKENHI-PROJECT-18H05272
[Journal Article] ミトコンドリアRNA修飾異常による疾患と治療2023
- Author(s)
  鈴木勉、友田愛奈、鈴木健夫、長尾翌手可
- Journal Title
  
  実験医学増刊ミトコンドリア疾患治療の新時代
  
  Volume: 41 Pages: 93-99
- Data Source
  KAKENHI-PROJECT-23K23475
[Journal Article] RNA修飾と疾患2021
- Author(s)
  鈴木健夫、鈴木勉
- Journal Title
  
  月刊「細胞」
  
  Volume: 53 Pages: 880-883
- Data Source
  KAKENHI-PLANNED-21H05280
[Journal Article] Mass spectrometric analysis of mRNA 5′ terminal modifications2021
- Author(s)
  Akichika, S., Suzuki, T., Suzuki, T.
- Journal Title
  
  Methods Enzymol
  
  Volume: 658 Pages: 407-418
- DOI
  10.1016/bs.mie.2021.06.012
- ISBN
  9780128235850
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21243, KAKENHI-PROJECT-20J30002, KAKENHI-PROJECT-18H05272
[Journal Article] N6-methyladenosine (m6A) is an endogenous A3 adenosine receptor ligand2021
- Author(s)
  Ogawa Akiko、Nagiri Chisae、Shihoya Wataru、Inoue Asuka、Kawakami Kouki、Hiratsuka Suzune、Aoki Junken、Ito Yasuhiro、Suzuki Takeo、Suzuki Tsutomu、Inoue Toshihiro、Nureki Osamu、Tanihara Hidenobu、Tomizawa Kazuhito、Wei Fan-Yan
- Journal Title
  
  Molecular Cell
  
  Volume: 81 Issue: 4 Pages: 674-674
- DOI
  10.1016/j.molcel.2020.12.038
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21243, KAKENHI-PROJECT-18H02094, KAKENHI-PROJECT-18H02599, KAKENHI-PROJECT-18H02865, KAKENHI-PROJECT-19J11256, KAKENHI-PROJECT-19K22246, KAKENHI-PROJECT-20K18371, KAKENHI-PUBLICLY-20H05309, KAKENHI-PROJECT-18H05272
[Journal Article] RNA修飾と疾患2021
- Author(s)
  鈴木健夫、鈴木勉
- Journal Title
  
  月刊「細胞」
  
  Volume: 53 Pages: 880-883
- Data Source
  KAKENHI-PROJECT-20K21243
[Journal Article] Loss of Ftsj1 perturbs codon-specific translation efficiency in the brain and is associated with X-linked intellectual disability2021
- Author(s)
  Nagayoshi Y.、Chujo T.、Hirata S.、Nakatsuka H.、Chen C.-W.、Takakura M.、Miyauchi K.、Ikeuchi Y.、Carlyle B. C.、Kitchen R. R.、Suzuki T.、Katsuoka F.、Yamamoto M.、Goto Y.、Tanaka M.、Natsume K.、Nairn A. C.、Suzuki T.、Tomizawa K.、Wei F.-Y.
- Journal Title
  
  Science Advances
  
  Volume: 7 Issue: 13
- DOI
  10.1126/sciadv.abf3072
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20643, KAKENHI-PROJECT-20K21243, KAKENHI-PLANNED-20H05786, KAKENHI-PROJECT-18H02094, KAKENHI-PROJECT-18H02599, KAKENHI-PROJECT-20H03187, KAKENHI-PROJECT-19K22246, KAKENHI-PUBLICLY-20H05309, KAKENHI-PROJECT-20K20838, KAKENHI-PROJECT-18H05272, KAKENHI-PROJECT-18K05430
[Journal Article] Complete chemical structures of human mitochondrial tRNAs2020
- Author(s)
  Suzuki Takeo、Yashiro Yuka、Kikuchi Ittoku、Ishigami Yuma、Saito Hironori、Matsuzawa Ikuya、Okada Shunpei、Mito Mari、Iwasaki Shintaro、Ma Ding、Zhao Xuewei、Asano Kana、Lin Huan、Kirino Yohei、Sakaguchi Yuriko、Suzuki Tsutomu
- Journal Title
  
  Nature Communications
  
  Volume: 11 Issue: 1 Pages: 1-15
- DOI
  10.1038/s41467-020-18068-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21243, KAKENHI-PROJECT-18H02094, KAKENHI-PROJECT-19K22246, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-17H04998, KAKENHI-PROJECT-18H05272, KAKENHI-PROJECT-19K22406, KAKENHI-PLANNED-20H05784
[Journal Article] Mass Spectrometric Analysis of Mitochondrial RNA Modifications2020
- Author(s)
  Ishigami Yuma、Suzuki Tsutomu、Suzuki Takeo
- Journal Title
  
  Methods in Molecular Biology
  
  Volume: 2192 Pages: 89-101
- DOI
  10.1007/978-1-0716-0834-0_8
- ISBN
  9781071608333, 9781071608340
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21243, KAKENHI-PROJECT-18H02094, KAKENHI-PROJECT-19K22246, KAKENHI-PROJECT-18H05272
[Journal Article] ミトコンドリアtRNA修飾とミトコンドリア病2020
- Author(s)
  鈴木健夫
- Journal Title
  
  遺伝子医学MOOK 35号ミトコンドリアと病気
  
  Volume: 35 Pages: 268-274
- Data Source
  KAKENHI-PROJECT-18H02094
[Journal Article] ミトコンドリアtRNA修飾とミトコンドリア病2020
- Author(s)
  鈴木健夫
- Journal Title
  
  遺伝子医学MOOK 35号ミトコンドリアと病気
  
  Volume: 35 Pages: 268-274
- Data Source
  KAKENHI-PROJECT-20K21243
[Journal Article] Impact of intron removal from tRNA genes on Saccharomyces cerevisiae2019
- Author(s)
  Hayashi Sachiko、Mori Shunsuke、Suzuki Takeo、Suzuki Tsutomu、Yoshihisa Tohru
- Journal Title
  
  Nucleic Acids Research
  
  Volume: - Issue: 11 Pages: 5936-5949
- DOI
  10.1093/nar/gkz270
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-17H05672, KAKENHI-PLANNED-26113003, KAKENHI-PROJECT-19K22246, KAKENHI-PROJECT-18H02094, KAKENHI-PROJECT-17K07289, KAKENHI-PROJECT-17KT0113, KAKENHI-PROJECT-18H05272
[Journal Article] Distinct Modified Nucleosides in tRNATrp from the Hyperthermophilic Archaeon Thermococcus kodakarensis and Requirement of tRNA m2G10/m22G10 Methyltransferase (Archaeal Trm11) for Survival at High Temperatures2019
- Author(s)
  Hirata Akira、Suzuki Takeo、Nagano Tomoko、Fujii Daishiro、Okamoto Mizuki、Sora Manaka、Lowe Todd M.、Kanai Tamotsu、Atomi Haruyuki、Suzuki Tsutomu、Hori Hiroyuki
- Journal Title
  
  Journal of Bacteriology
  
  Volume: 201 Issue: 21 Pages: 1-17
- DOI
  10.1128/jb.00448-19
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06088, KAKENHI-PROJECT-19K22246, KAKENHI-PROJECT-18H02094, KAKENHI-PROJECT-18H05272
[Journal Article] Mammalian NSUN2 introduces 5-methylcytidines into mitochondrial tRNAs2019
- Author(s)
  Shinoda Saori、Kitagawa Sho、Nakagawa Shinichi、Wei Fan-Yan、Tomizawa Kazuhito、Araki Kimi、Araki Masatake、Suzuki Takeo、Suzuki Tsutomu
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 47 Issue: 16 Pages: 8734-8745
- DOI
  10.1093/nar/gkz575
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22246, KAKENHI-PROJECT-18H02094, KAKENHI-PROJECT-19J00899, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-18H05272, KAKENHI-PROJECT-18H02599
[Journal Article] Higd1a improves respiratory function in the models of mitochondrial disorder2019
- Author(s)
  Nagao Takemasa、Shintani Yasunori、Hayashi Takaharu、Kioka Hidetaka、Kato Hisakazu、Nishida Yuya、Yamazaki Satoru、Tsukamoto Osamu、Yashirogi Shohei、Yazawa Issei、Asano Yoshihiro、Shinzawa‐Itoh Kyoko、Imamura Hiromi、Suzuki Takeo、Suzuki Tsutomu、Goto Yu‐ichi、Takashima Seiji
- Journal Title
  
  The FASEB Journal
  
  Volume: 34 Issue: 1 Pages: 1859-1871
- DOI
  10.1096/fj.201800389r
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08105, KAKENHI-PROJECT-19K08581, KAKENHI-PROJECT-19K22246, KAKENHI-PROJECT-17H03646, KAKENHI-PROJECT-17H03654, KAKENHI-PROJECT-18H02094, KAKENHI-PROJECT-17K09577, KAKENHI-PROJECT-19K09408, KAKENHI-PROJECT-18H05272, KAKENHI-PROJECT-19K22386, KAKENHI-PROJECT-19H03652, KAKENHI-PROJECT-18K19547, KAKENHI-PROJECT-17K09578
[Journal Article] ヒドロキシル化2018
- Author(s)
  鈴木, 健夫、鈴木, 勉
- Journal Title
  
  生体の科学
  
  Volume: 69 Pages: 398-399
- Data Source
  KAKENHI-PROJECT-18K19141
[Journal Article] Defective Mitochondrial tRNA Taurine Modification Activates Global Proteostress and Leads to Mitochondrial Disease.2018
- Author(s)
  Fakruddin M, Wei FY, Suzuki T, Asano K, Kaieda T, Omori A, Izumi R, Fujimura A, Kaitsuka T, Miyata K, Araki K, Oike Y, Scorrano L, Suzuki T, Tomizawa K.
- Journal Title
  
  Cell Rep.
  
  Volume: 22 Issue: 2 Pages: 482-496
- DOI
  10.1016/j.celrep.2017.12.051
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KT0054, KAKENHI-PROJECT-26702035, KAKENHI-PROJECT-26220205, KAKENHI-PROJECT-16K15482, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-18K19521, KAKENHI-PLANNED-26113003, KAKENHI-PROJECT-16K18989, KAKENHI-PROJECT-18H02599
[Journal Article] ヒドロキシル化2018
- Author(s)
  鈴木, 健夫、鈴木, 勉
- Journal Title
  
  生体の科学
  
  Volume: 69 Pages: 389-399
- Data Source
  KAKENHI-PROJECT-18H02094
[Journal Article] Cap-specific terminal N6-methylation of RNA by an RNA polymerase II?associated methyltransferase2018
- Author(s)
  Akichika Shinichiro、Hirano Seiichi、Shichino Yuichi、Suzuki Takeo、Nishimasu Hiroshi、Ishitani Ryuichiro、Sugita Ai、Hirose Yutaka、Iwasaki Shintaro、Nureki Osamu、Suzuki Tsutomu
- Journal Title
  
  Science
  
  Volume: 363 Issue: 363 Pages: 1-7
- DOI
  10.1126/science.aav0080
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07282, KAKENHI-PROJECT-18K19141, KAKENHI-PUBLICLY-17H05592, KAKENHI-ORGANIZER-26113001, KAKENHI-PLANNED-26113003, KAKENHI-PROJECT-17H03640, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19J11333, KAKENHI-PROJECT-16H06294, KAKENHI-PROJECT-18H05272, KAKENHI-PROJECT-18H02384, KAKENHI-PUBLICLY-17H05679, KAKENHI-PROJECT-17H04998
[Journal Article] Metabolic and chemical regulation of tRNA modification associated with taurine deficiency and human disease2018
- Author(s)
  Asano Kana、Suzuki Takeo、Saito Ayaka、Wei Fan-Yan、Ikeuchi Yoshiho、Numata Tomoyuki、Tanaka Ryou、Yamane Yoshihisa、Yamamoto Takeshi、Goto Takanobu、Kishita Yoshihito、Murayama Kei、Ohtake Akira、Okazaki Yasushi、Tomizawa Kazuhito、Sakaguchi Yuriko、Suzuki Tsutomu
- Journal Title
  
  Nucleic Acids Res.
  
  Volume: 46 Issue: 4 Pages: 1565-1583
- DOI
  10.1093/nar/gky068
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26702035, KAKENHI-PROJECT-26220205, KAKENHI-PROJECT-16H04759, KAKENHI-PROJECT-18K19521, KAKENHI-PLANNED-26113003, KAKENHI-PROJECT-18H02599
[Journal Article] Identification of 2-methylthio cyclic N6-threonylcarbamoyladenosine (ms2ct6A) as a novel RNA modification at position 37 of tRNAs2017
- Author(s)
  Kang, B. I., Miyauchi, K., Matuszewski, M., D'Almeida, G. S., Rubio, M. A., Alfonzo, J. D., Inoue, K., Sakaguchi, Y., Suzuki, T., Sochacka, E., Suzuki, T.
- Journal Title
  
  Nucleic Acids Res
  
  Volume: 45 Issue: 4 Pages: 2124-2136
- DOI
  10.1093/nar/gkw1120
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26702035, KAKENHI-INTERNATIONAL-15K21720, KAKENHI-PLANNED-26113003, KAKENHI-PROJECT-26220205
[Journal Article] ALKBH1 is an RNA dioxygenase responsible for cytoplasmic and mitochondrial tRNA modifications2017
- Author(s)
  Kawarada Layla、Suzuki Takeo、Ohira Takayuki、Hirata Shoji、Miyauchi Kenjyo、Suzuki Tsutomu
- Journal Title
  
  Nucleic Acids Res.
  
  Volume: 45 Issue: 12 Pages: 7401-7415
- DOI
  10.1093/nar/gkx354
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26702035, KAKENHI-PROJECT-26220205, KAKENHI-PLANNED-26113003
[Journal Article] Mtu1-mediated thiouridine formation of mitochondrial tRNAs is required for mitochondrial translation and is involved in reversible infantile liver injury2016
- Author(s)
  Wu, Y., Wei, F. Y., Kawarada, L., Suzuki, T., Araki, K., Komohara, Y., Fujimura, A., Kaitsuka, T., Takeya, M., Oike, Y., Suzuki, T., Tomizawa, K.
- Journal Title
  
  PLoS genetics
  
  Volume: 12 Issue: 9 Pages: e1006355-e1006355
- DOI
  10.1371/journal.pgen.1006355
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26702035, KAKENHI-PROJECT-15K08178, KAKENHI-PROJECT-16K07093, KAKENHI-PROJECT-16K18989, KAKENHI-PLANNED-26113003, KAKENHI-PROJECT-26220205
[Journal Article] NSUN3 methylase initiates 5-formylcytidine biogenesis in human mitochondrial tRNA(Met)2016
- Author(s)
  Nakano, S., Suzuki, T., Kawarada, L., Iwata, H., Asano, K., Suzuki, T.
- Journal Title
  
  Nat Chem Biol
  
  Volume: 12 Issue: 7 Pages: 546-51
- DOI
  10.1038/nchembio.2099
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26702035, KAKENHI-PLANNED-26113003, KAKENHI-PROJECT-26220205
[Journal Article] Cdk5rap1-mediated 2-methylthio modification of mitochondrial tRNAs governs protein translation and contributes to myopathy in mice and humans.2015
- Author(s)
  Wei FY, Zhou B, Suzuki T, Miyata K, Ujihara Y, Horiguchi H, Takahashi N, Xie P, Michiue H, Fujimura A, Kaitsuka T, Matsui H, Koga Y, Mohri S, Suzuki T, Oike Y, Tomizawa K.
- Journal Title
  
  Cell Metab
  
  Volume: 21 Issue: 3 Pages: 413-6
- DOI
  10.1016/j.cmet.2015.01.019
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390293, KAKENHI-PROJECT-24791502, KAKENHI-PROJECT-25461114, KAKENHI-PROJECT-25461571, KAKENHI-PROJECT-25620125, KAKENHI-PUBLICLY-26116722, KAKENHI-PROJECT-26220205, KAKENHI-PROJECT-26282127, KAKENHI-PROJECT-26293190, KAKENHI-PROJECT-26560442, KAKENHI-PROJECT-26670284, KAKENHI-PROJECT-26670405, KAKENHI-PROJECT-26702035, KAKENHI-PROJECT-15K08178, KAKENHI-PLANNED-26113003
[Journal Article] RNAの修飾欠損と疾患2015
- Author(s)
  鈴木勉、浅野奏、鈴木健夫
- Journal Title
  
  ファルマシア
  
  Volume: 51 Pages: 32-36
- NAID
  130007447866
- Data Source
  KAKENHI-PROJECT-26702035
[Journal Article] A single methylation of 23S rRNA triggers late steps of 50S ribosomal subunit assembly2015
- Author(s)
  Arai, T., Ishiguro, K., Kimura, S., Sakaguchi, Y., Suzuki, T. and Suzuki, T.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA.
  
  Volume: 112 Issue: 34
- DOI
  10.1073/pnas.1506749112
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-26113003, KAKENHI-PROJECT-26560442, KAKENHI-PROJECT-26702035, KAKENHI-ORGANIZER-26113001, KAKENHI-PROJECT-26220205
[Journal Article] RNAの修飾欠損と疾患2015
- Author(s)
  鈴木勉、浅野奏、鈴木健夫
- Journal Title
  
  ファルマシア
  
  Volume: 51 Pages: 32-36
- NAID
  130007447866
- Data Source
  KAKENHI-PROJECT-26560442
[Journal Article] Structural Dynamics of a Mitochondrial tRNA Possessing Weak Thermo dynamic Stability2014
- Author(s)
  Hari Bhaskaran, Takaaki Taniguchi, Takeo Suzuki, Tsutomu Suzuki, and John J. Perona
- Journal Title
  
  Biochemistry
  
  Volume: 53(a) Issue: 9 Pages: 1456-1465
- DOI
  10.1021/bi401449z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13J09837, KAKENHI-PLANNED-21115003, KAKENHI-PROJECT-22227006, KAKENHI-PROJECT-25620125
[Journal Article] A complete landscape of post-transcriptional modifications in mammalian mitochondrial tRNAs2014
- Author(s)
  Suzuki T. and Suzuki T.
- Journal Title
  
  Nucleic Acids Research
  
  Volume: (in press) Issue: 11 Pages: 7346-7357
- DOI
  10.1093/nar/gku390
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-21115003, KAKENHI-PROJECT-22227006, KAKENHI-PROJECT-25620125, KAKENHI-PROJECT-26220205, KAKENHI-PROJECT-26560442, KAKENHI-PROJECT-26702035, KAKENHI-PLANNED-26113003
[Journal Article] Biochemical and mass spectrometric analysis of 3'-end methylation of piRNAs2014
- Author(s)
  Suzuki T, Miyauchi K, Sakaguchi Y, Suzuki T
- Journal Title
  
  Methods Mol. Biol
  
  Volume: 1093 Pages: 59-72
- DOI
  10.1007/978-1-62703-694-8_6
- ISBN
  9781627036931, 9781627036948
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21115003, KAKENHI-PROJECT-22227006, KAKENHI-PROJECT-25620125
[Journal Article] A single acetylation of 18S rRNA is essential for biogenesis of the small ribosomal subunit in Saccharomyces cerevisiae2014
- Author(s)
  Ito, S., Akamatsu, Y., Noma, A., Kimura, S., Miyauchi, K., Ikeuchi, Y., Suzuki, T. and Suzuki, T
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 289 Issue: 38 Pages: 26201-26212
- DOI
  10.1074/jbc.m114.593996
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25620125, KAKENHI-PROJECT-26220205, KAKENHI-PROJECT-26560442, KAKENHI-PROJECT-26702035, KAKENHI-PLANNED-26113003
[Journal Article] 5-Hydroxymethylcytosine plays a critical role in glioblastomagenesis by recruiting the CHTOP-Methylosome complex2014
- Author(s)
  Hiroki Takai, Tetsu Akiyama et al.
- Journal Title
  
  Cell Reports
  
  Volume: 9 Issue: 1 Pages: 48
- DOI
  10.1016/j.celrep.2014.08.071
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-14J10908, KAKENHI-ORGANIZER-22112001, KAKENHI-PLANNED-22112004, KAKENHI-PROJECT-24390340, KAKENHI-PROJECT-24501313, KAKENHI-PUBLICLY-25134702, KAKENHI-PROJECT-25620125, KAKENHI-PROJECT-26220205, KAKENHI-PROJECT-26253073, KAKENHI-PROJECT-26293321, KAKENHI-PROJECT-26560442, KAKENHI-PROJECT-26702035, KAKENHI-PLANNED-23114003, KAKENHI-PLANNED-26113003
[Journal Article] Human NAT10 is an ATP-dependent RNA acetyltransferase responsible for N4-acetylcytidine formation in 18S rRNA2014
- Author(s)
  Satoshi Ito, Sayuri Horikawa, Tateki Suzuki, Hiroki Kawauchi, Yoshikazu Tanaka, Takeo Suzuki, and Tsutomu Suzuki
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 289 Issue: 52 Pages: 35724-35730
- DOI
  10.1074/jbc.c114.602698
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-25620125, KAKENHI-PUBLICLY-26102501, KAKENHI-PROJECT-26220205, KAKENHI-PROJECT-26291008, KAKENHI-PROJECT-26560442, KAKENHI-PROJECT-26702035, KAKENHI-PLANNED-26113003
[Journal Article] Decoding mechanism of non-universal genetic codes in Loligo bleekeri mitochondria2013
- Author(s)
  Ohira T, Suzuki T (第2著者), 他5名
- Journal Title
  
  J . Biol. Chem
  
  Volume: 288 Issue: 11 Pages: 7645-7652
- DOI
  10.1074/jbc.m112.439554
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21115003, KAKENHI-PROJECT-22227006, KAKENHI-PROJECT-23655153, KAKENHI-PROJECT-23710265, KAKENHI-PROJECT-24370093, KAKENHI-PUBLICLY-23112705
[Journal Article] The comprehensive epigenome map of piRNA clusters2013
- Author(s)
  Kawaoka S, Hara K, Shoji K, Kobayashi M, Shimada T, Sugano S, Tomari Y, Suzuki Y, Katsuma S
- Journal Title
  
  Nucleic Acids Res
  
  Volume: 41(3) Pages: 1581-1590
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-21115001
[Journal Article] Quantitative PCR measurement of tRNA 2 methylthio modification for assessing type 2 diabetes risk.2013
- Author(s)
  Kie, Pei-Yu, et al.
- Journal Title
  
  Clinical Chemistry
  
  Volume: 59 Issue: 11 Pages: 1604-1612
- DOI
  10.1373/clinchem.2013.210401
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-12F02425, KAKENHI-PLANNED-21115003, KAKENHI-PROJECT-22227006, KAKENHI-PROJECT-25620125, KAKENHI-PROJECT-25860753
[Journal Article] Crystal structure of a putative methyltransferase SAV1081 from Staphylococcus aureus2013
- Author(s)
  Kita, S., Tanaka, Y., Hirano, N., Kimura, S., Suzuki, T., Suzuki, T., Yao, M. and Tanaka, I.
- Journal Title
  
  Protein & Peptide Letters
  
  Volume: 20 Issue: 5 Pages: 530-537
- DOI
  10.2174/0929866511320050006
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-22227006, KAKENHI-PROJECT-23710265, KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-25620125, KAKENHI-PLANNED-21115003
[Journal Article] Targeted gene silencing in mouse germ cells by insertion of a homologous DNA into a piRNA generating locus2013
- Author(s)
  Yamamoto Y, Watanabe T, Hoki Y, Shirane K, Li Y, Ichiiyanagi K, Kuramochi-Miyagawa S, Toyoda A, Fujiyama A, Oginuma M, Suzuki H, Sado T, Nakano T, Sasaki H
- Journal Title
  
  Genome Res
  
  Volume: 23(2) Pages: 292-299
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-21115001
[Journal Article] Hsp90 facilitates accurate loading of precursor piRNAs into PIWI proteins2013
- Author(s)
  Izumi N, Kawaoka S, Yasuhara S, Suzuki Y, Sugano S, Katsuma S, Tomari Y.
- Journal Title
  
  RNA
  
  Volume: 19(7) Pages: 896-901
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-21115001
[Journal Article] A role for transcription from a piRNA cluster in de novo piRNA production2012
- Author(s)
  Kawaoka S, Mitsutake H, Kiuchi T, Kobayashi M, Yoshikawa M, Suzuki Y, Sugano S, Shimada T, Kobayashi J, Tomari Y, Katsuma S
- Journal Title
  
  RNA
  
  Volume: 18(2) Pages: 265-273
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-21115001
[Journal Article] Base methylations in the double-stranded RNA by a fused methyltransferase bearing unwinding activity2012
- Author(s)
  Kimura S., Ikeuchi Y., Kitahara K., Sakaguchi Y., Suzuki T., Suzuki T.
- Journal Title
  
  Nucleic Acids Research
  
  Volume: (掲載確定)(印刷中) Issue: 9 Pages: 4071-4085
- DOI
  10.1093/nar/gkr1287
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J09964, KAKENHI-PLANNED-21115003, KAKENHI-PROJECT-22227006, KAKENHI-PUBLICLY-23112705, KAKENHI-PROJECT-23655153, KAKENHI-PROJECT-23710265, KAKENHI-ORGANIZER-20112001
[Journal Article] Actin-binding protein ABP140 is a methyltransferase for 3-methylcytidine at position 32 of tRNAs in Saccharomyces cerevisiae2011
- Author(s)
  Noma A, Yi S, Katoh T, Takai Y, Suzuki T and Suzuki T
- Journal Title
  
  RNA
  
  Volume: 17 Issue: 6 Pages: 1111-1119
- DOI
  10.1261/rna.2653411
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21115003, KAKENHI-PROJECT-21227005, KAKENHI-PROJECT-22227006, KAKENHI-PUBLICLY-23112705, KAKENHI-PROJECT-23655153, KAKENHI-PROJECT-23710265
[Journal Article] Molecular basis of dihydrouridine formation on tRNA2011
- Author(s)
  Yu F, Tanaka Y, Yamashita K, Suzuki T (第4著者), 他4名
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 108 Issue: 49 Pages: 19593-19598
- DOI
  10.1073/pnas.1112352108
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21115003, KAKENHI-PROJECT-22227006, KAKENHI-PUBLICLY-23112705, KAKENHI-PROJECT-23655153, KAKENHI-PROJECT-23710265
[Journal Article] Human Mitochondrial tRNAs: Biogenesis, Function, Structural Aspects, and Diseases.2011
- Author(s)
  Tsutomu Suzuki, Asuteka Nagao and Takeo Suzuki
- Journal Title
  
  Annu. Rev. Genet.
  
  Volume: 45 Pages: 299-329
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23710265
[Journal Article] Taurine-containing uridine modifications in tRNA anticodons are required to decipher non-universal genetic codes in ascidian mitochondria2011
- Author(s)
  Takeo Suzuki, Kenjyo Miyauchi, Tsutomu Suzuki, Shin-ichi Yokobori, Naoki Shigi, Akiko Kondow, Nono Takeuchi, Akihiko Yamagishi, Kimitsuna Watanabe
- Journal Title
  
  J.Biol.Chem.
  
  Volume: 286 Pages: 35494-8
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21115003
[Journal Article] Human mitochondrial diseases caused by lack of taurine-modification in mitochondrial tRNAs2011
- Author(s)
  Suzuki, T., et al.
- Journal Title
  
  WIREs RNA
  
  Volume: 2 Pages: 376-386
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21115003
[Journal Article] Actin-binding protein ABP140 is a methyltransferase for 3-methylcytidine at position 32 of tRNAs in Saccharomyces cerevisiae2011
- Author(s)
  Akiko Noma, Sanghyun Yi, Takayuki Katoh, Yoshimi Takai, Takeo Suzuki, Tsutomu Suzuki
- Journal Title
  
  RNA
  
  Volume: 17 Pages: 1111-9
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21115003
[Journal Article] Molecular basis of dihydrouridine formation on tRNA2011
- Author(s)
  Futao Yu, Yoshikazu Tanaka, Keitaro Yamashita, Takeo Suzuki, Akiyoshi Nakamura, Nagisa Hirano, Tsutomu Suzuki, Min Yao, Isao Tanaka
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 108 Pages: 19593-8
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21115003
[Journal Article] Loss of ribosomal RNA modification causes developmental defects in zebrafish2011
- Author(s)
  Sayomi Higa-Nakamine, Takeo Suzuki, Tamayo Uechi, Anirban Chakraborty, Yukari Nakajima, Mikako Nakamura, Naoko Hirano, Tsutomu Suzuki, Naoya Kenmochi
- Journal Title
  
  Nucleic Acids Research.
  
  Volume: 40 Pages: 391-8
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21115003
[Journal Article] Human Mitochondrial tRNAs : Biogenesis, Function, Structural Aspects, and Diseases2011
- Author(s)
  Tsutomu Suzuki, Asuteka Nagao, Takeo Suzuki
- Journal Title
  
  Annu.Rev.Genet.
  
  Volume: 45 Pages: 299-329
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21115003
[Journal Article] Molecular basis of dihydrouridine formation on tRNA2011
- Author(s)
  Futao Yu, Yoshikazu Tanaka, Keitaro Yamashita, Takeo Suzuki, Akiyoshi Nakamura, Nagisa Hirano, Tsutomu Suzuki, Min Yao, Isao Tanaka
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 108 Pages: 19593-19598
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23710265
[Journal Article] Loss of ribosomal RNA modification causes developmental defects in zebrafish2011
- Author(s)
  Sayomi Higa-Nakamine, Takeo Suzuki, Tamayo Uechi, Anirban Chakraborty, Yukari Nakajima, Mikako Nakamura, Naoko Hirano, Tsutomu Suzuki and Naoya Kenmochi
- Journal Title
  
  Nucleic Acids Research.
  
  Volume: 40 Pages: 391-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23710265
[Journal Article] Actin-binding protein ABP140 is a methyltransferase for 3-methylcytidine at position 32 of tRNAs in Saccharomyces cerevisiae2011
- Author(s)
  Akiko Noma, Sanghyun Yi, Takayuki Katoh, Yoshimi Takai, Takeo Suzuki and Tsutomu Suzuki
- Journal Title
  
  RNA
  
  Volume: 17 Pages: 1111-1119
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23710265
[Journal Article] Deficit of Lys-tRNA Modification by Cdkal1 Causes the Development of Type 2 Diabetes in Mice2011
- Author(s)
  FY Wei, T Suzuki, S Watanabe, S Kimura, T Kaitsuka, A Fujimura, H Matsui, M Atta, H Michiue, M Fontecave, K Yamagata, T Suzuki and K Tomizawa
- Journal Title
  
  J. Clin. Invest.
  
  Volume: 121 Pages: 3598-608
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23710265
[Journal Article] Human mitochondrial diseases caused by lack of taurine-modification in mitochondrial tRNAs2011
- Author(s)
  Suzuki T, Nagao A and Suzuki T
- Journal Title
  
  Wiley Interdiscip Rev RNA
  
  Volume: 2 Issue: 3 Pages: 376-386
- DOI
  10.1002/wrna.65
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21115003, KAKENHI-PUBLICLY-23112705, KAKENHI-PROJECT-23655153, KAKENHI-PROJECT-23710265
[Journal Article] The silkworm W chromosome is a source of female-enriched piRNAs2011
- Author(s)
  Kawaoka S, Kadota K, Arai Y, Suzuki Y, Fujii T, Abe H, Yasukochi Y, Mita K, Sugano S, Shimizu K, Tomari Y, Shimada T, Katsuma S
- Journal Title
  
  RNA
  
  Volume: 17(12) Pages: 2144-2151
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-21115001
[Journal Article] Human Mitochondrial tRNAs : Biogenesis, Function, Structural Aspects, and Diseases2011
- Author(s)
  Suzuki T, Nagao A and Suzuki T
- Journal Title
  
  Annu. Rev. Genet
  
  Volume: 45 Issue: 1 Pages: 299-329
- DOI
  10.1146/annurev-genet-110410-132531
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21115003, KAKENHI-PROJECT-22227006, KAKENHI-PUBLICLY-23112705, KAKENHI-PROJECT-23710265
[Journal Article] Deficit of Lys-tRNA Modification by Cdkal1 Causes the Development of Type 2 Diabetes in Mice2011
- Author(s)
  FY Wei, T Suzuki, S Watanabe, S Kimura, T Kaitsuka, A Fujimura, H Matsui, M Atta, H Michiue, M Fontecave, K Yamagata, T Suzuki, K Tomizawa
- Journal Title
  
  J.Clin.Invest.
  
  Volume: 121 Pages: 3598-608
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21115003
[Journal Article] Zygotic amplification of secondary piRNAs during silkworm embryogenesis2011
- Author(s)
  Kawaoka S, Arai Y, Kadota K, Suzuki Y, Hara K, Sugano S, Shimizu K, Tomari Y, Shimada T, Katsuma S
- Journal Title
  
  RNA
  
  Volume: 17(7) Pages: 1401-1407
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-21115001
[Journal Article] Deficit of tRNA(Lys) modification by Cdkall causes the development of type 2 diabetes in mice2011
- Author(s)
  Wei FY., Suzuki T., Watanabe S., Kimura S., Kaitsuka T., Fujimura A., Matsui H., Atta M., Michiue H., Fontecave M., Yamagata K., Suzuki T., Tomizawa K.
- Journal Title
  
  The Journal of Clinical Investigation
  
  Volume: 121 Issue: 9 Pages: 3598-3608
- DOI
  10.1172/jci58056
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J09964, KAKENHI-PLANNED-21115003, KAKENHI-PROJECT-21220010, KAKENHI-PROJECT-22227006, KAKENHI-PROJECT-22790214, KAKENHI-PUBLICLY-23112705, KAKENHI-PROJECT-23655153, KAKENHI-PROJECT-23710265
[Journal Article] Loss of ribosomal RNA modification causes developmental defects in zebrafish2011
- Author(s)
  Higa-Nakamine S, Suzuki T (第2著者) 他7名
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 40 Issue: 1 Pages: 391-398
- DOI
  10.1093/nar/gkr700
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21115003, KAKENHI-PROJECT-22227006, KAKENHI-PROJECT-22370065, KAKENHI-PROJECT-22659186, KAKENHI-PROJECT-22790989, KAKENHI-PUBLICLY-23112705, KAKENHI-PROJECT-23500451, KAKENHI-PROJECT-23655153, KAKENHI-PROJECT-23710265, KAKENHI-PROJECT-24659476, KAKENHI-PROJECT-24700381
[Journal Article] Taurine-containing uridine modifications in tRNA anticodons are required to decipher non-universal genetic codes in ascidian mitochondria2011
- Author(s)
  Suzuki T (第1著者), 他8名
- Journal Title
  
  J. Biol. Chem
  
  Volume: 286 Issue: 41 Pages: 35494
- DOI
  10.1074/jbc.m111.279810
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21115003, KAKENHI-PROJECT-21570101, KAKENHI-PROJECT-21570242, KAKENHI-PROJECT-22227006, KAKENHI-PUBLICLY-23112705, KAKENHI-PROJECT-23655153, KAKENHI-PROJECT-23710265, KAKENHI-PROJECT-23770202
[Journal Article] Human mitochondrial diseases caused by lack of taurine-modification in mitochondrial tRNAs2011
- Author(s)
  Tsutomu Suzuki, Asuteka Nagao, Takeo Suzuki
- Journal Title
  
  WIREs RNA
  
  Volume: 121 Pages: 376-86
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21115003
[Journal Article] Taurine-containing uridine modifications in tRNA anticodons are required to decipher non-universal genetic codes in ascidian mitochondria2011
- Author(s)
  Takeo Suzuki, Kenjyo Miyauchi, Tsutomu Suzuki, Shin-ichi Yokobori, Naoki Shigi, Akiko Kondow, Nono Takeuchi, Akihiko Yamagishi, and Kimitsuna Watanabe
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 286 Pages: 35494-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23710265
[Journal Article] Human mitochondrial diseases caused by lack of taurine-modification in mitochondrial tRNAs2011
- Author(s)
  Tsutomu Suzuki, Asuteka Nagao and Takeo Suzuki
- Journal Title
  
  WIREs RNA
  
  Volume: 2 Pages: 376-386
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23710265
[Journal Article] Agmatine-conjugated cytidine in tRNA anticodon essential for AUA decoding in archaea2010
- Author(s)
  Ikeuchi Y, Kimura S, Numata T, Nakamura D, Yokogawa T, Ogata T, Wada T, Suzuki T and Suzuki T
- Journal Title
  
  Nat. Chem. Biol
  
  Volume: 6 Issue: 4 Pages: 277-282
- DOI
  10.1038/nchembio.323
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21115003
[Journal Article] Agmatine-conjugated cytidine in a tRNA anticodon is essential for AUA decoding in archaea2010
- Author(s)
  Ikeuchi Y, Kimura S, Numata T, Nakamura D, Yokogawa T, Ogata T, Wada T, Suzuki T, Suzuki T
- Journal Title
  
  Nat Chem Biol
  
  Volume: 6(4) Pages: 277-282
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-21115001
[Journal Article] ミトコンドリア脳筋症とtRNAのタウリン修飾欠損2010
- Author(s)
  鈴木勉、鈴木健夫
- Journal Title
  
  細胞工学
  
  Volume: 29 Pages: 137-143
- Data Source
  KAKENHI-PLANNED-21115003
[Journal Article] Hsc70/Hsp90 chaperone machinery mediates ATP-dependent RISC loading of small RNA duplexes2010
- Author(s)
  Iwasaki S, Kobayashi M, Yoda M, Sakaguchi Y, Katsuma S, Suzuki T, Tomari Y
- Journal Title
  
  Mol Cell
  
  Volume: 39(2) Pages: 292-299
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-21115001
[Patent] RNA 修飾の簡易検出法、及び該検出法を用いた2型糖尿病の検査方法2013
- Inventor(s)
  富澤一仁、魏范研、鈴木健夫、鈴木勉
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-047278
- Filing Date
  2013-03-08
- Data Source
  KAKENHI-PLANNED-21115003
[Presentation] 4.5SHノンコーディングRNAはSINE B1の異常なエキソン化を抑える解毒剤である2023
- Author(s)
  芳本玲、中山雄太、野村郁子、山本育子、栗原美寿々、鈴木雄、小林武彦、秦裕子、尾山大明、水戸麻理、岩崎信太郎、山崎智弘、廣瀬哲郎、荒木喜美、中川真一
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PLANNED-21H05280
[Presentation] ミトコンドリア病原性変異tRNAの活性化によるミトコンドリア機能の賦活化2023
- Author(s)
  友田愛奈、長尾翌手可、白井悠暉、浅野奏、鈴木健夫、Battersby Brendan J.、鈴木勉
- Organizer
  日本ミトコンドリア学会第21回年会
- Data Source
  KAKENHI-PROJECT-23K23475
[Presentation] Chemical switching of tRNA modification and its impact on mitochondrial protein synthesis in congenital metabolic disorder2023
- Author(s)
  A. Murayama-Maeda, T. Suzuki, K. Miyauchi, Y. Sakaguchi, T. Suzuki
- Organizer
  第24回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-23K23475
[Presentation] 精緻な翻訳の制御を担うtRNA修飾2022
- Author(s)
  鈴木健夫
- Organizer
  第45回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PLANNED-21H05280
[Presentation] 精緻な翻訳の制御を担うtRNA修飾2022
- Author(s)
  鈴木健夫
- Organizer
  第45回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-23K23475
[Presentation] Structural and functional analyses of a novel RNA methylation found in mammals2022
- Author(s)
  藤尾泰之、鈴木健夫、宮内健常、坂口裕理子、鈴木勉
- Organizer
  第23回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-23K23475
[Presentation] Restoration of mitochondrial function through activation of hypomodified tRNAs with pathogenic mutations associated with mitochondrial diseases2021
- Author(s)
  Tomoda, E., Nagao, A., Shirai, Y., Suzuki, T., Brendan, B., Suzuki, T.
- Organizer
  44th Annual meeting of the MBSJ
- Data Source
  KAKENHI-PROJECT-20K21243
[Presentation] Identification and characterization of novel tRNA methyltransferases in higher eukaryotes2021
- Author(s)
  Mineo, A., Akichika, S., Sakaguchi, Y., Shichino, Y., Mito, M., Iwasaki, S., Suzuki, T., Suzuki, T.
- Organizer
  44th Annual meeting of the MBSJ
- Data Source
  KAKENHI-PROJECT-20K21243
[Presentation] Biogenesis and Regulation of tRNA Modifications Associated with Human Diseases2020
- Author(s)
  Takeo Suzuki
- Organizer
  4th ETH Zurich - The University of Tokyo Strategic Partnership Symposium: Innovations in Chemical Biology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02094
[Presentation] Identification and characterization of tRNA queuosine-glycosyltransferase in mammal2019
- Author(s)
  Ma, D., Zhao, X., Suzuki, T., Suzuki, T.
- Organizer
  20th Takeda Science Foundation Symposium on Bioscience, RNA Neobiology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19141
[Presentation] Mammalian NSUN2 introduces 5-methylcytidines into mitochondrial tRNAs2019
- Author(s)
  Shinoda, S., Kitagawa, S., Nakagawa, S., Wei, F. Y., Tomizawa, K., Araki, K., Araki, M., Suzuki, T., Suzuki, T.
- Organizer
  21st RNA meeting
- Data Source
  KAKENHI-PROJECT-18H02094
[Presentation] Biogenesis and regulation of mitochondrial tRNA modifications associated with mitochondrial diseases2019
- Author(s)
  Takeo Suzuki
- Organizer
  Joint meeting of the 16th Conference ASMRM and the 19th Conference J-mit
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02094
[Presentation] Cap-specific terminal N6-methylation of RNA by an RNA polymerase II-associated methyltransferase2019
- Author(s)
  Akichika, S., Hirano, S., Shichino, Y., Suzuki, T., Nishimasu, H., Ishitani, R., Sugita, A., Hirose, Y., Iwasaki, S., Nureki, O., Suzuki, T.
- Organizer
  20th Takeda Science Foundation Symposium on Bioscience, RNA Neobiology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19141
[Presentation] Cap-specific terminal N6-methylation of RNA by an RNA polymerase II-associated methyltransferase2019
- Author(s)
  Akichika, S., Hirano, S., Shichino, Y., Suzuki, T., Nishimasu, H., Ishitani, R., Sugita, A., Hirose, Y., Iwasaki, S., Nureki, O., Suzuki, T.
- Organizer
  20th Takeda Science Foundation Symposium on Bioscience, RNA Neobiology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02094
[Presentation] Cap-specific terminal N6-methylation of RNA by an RNA polymerase II-associated methyltransferase2019
- Author(s)
  Akichika, S., Hirano, S., Shichino, Y., Suzuki, T., Nishimasu, H., Ishitani, R., Sugita, A., Hirose, Y., Iwasaki, S., Nureki, O., Suzuki, T.
- Organizer
  21st RNA meeting
- Data Source
  KAKENHI-PROJECT-18K19141
[Presentation] Identification and characterization of tRNA queuosine-glycosyltransferase in mammal2019
- Author(s)
  Ma, D., Zhao, X., Suzuki, T., Suzuki, T.
- Organizer
  20th Takeda Science Foundation Symposium on Bioscience, RNA Neobiology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02094
[Presentation] ヒト疾患に関わるtRNAタウリン修飾の生合成と代謝制御2018
- Author(s)
  Suzuki, T., Asano, K., Saito, A., Wei, F. Y., Tomizawa, K., Sakaguchi, Y., Suzuki, T.
- Organizer
  20th RNA meeting
- Data Source
  KAKENHI-PROJECT-18H02094
[Presentation] ヒト疾患に関わるtRNAタウリン修飾の生合成と代謝制御2018
- Author(s)
  Suzuki, T., Asano, K., Saito, A., Wei, F. Y., Tomizawa, K., Sakaguchi, Y., Suzuki, T.
- Organizer
  20th RNA meeting
- Data Source
  KAKENHI-PROJECT-18K19141
[Presentation] ミトコンドリアにおける暗号解読の担い手：tRNA修飾2018
- Author(s)
  鈴木, 健夫
- Organizer
  第18回日本ミトコンドリア学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18K19141
[Presentation] ミトコンドリアにおける暗号解読の担い手：tRNA修飾2018
- Author(s)
  鈴木, 健夫
- Organizer
  第18回日本ミトコンドリア学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02094
[Presentation] ALKBH1 mediates 5-formylcytidine biogenesis in mammalian tRNAs2017
- Author(s)
  Layla Kawarada, Takeo Suzuki, Tsutomu Suzuki
- Organizer
  Conbio2017
- Data Source
  KAKENHI-PROJECT-26702035
[Presentation] Thermophilic archaeal tRNAs are stabilized by N4-acetylcyridine modification2017
- Author(s)
  Ohira, T., Chen, M., Kurihashi, T., Yamauchi, R., Ito, S., Kaneko, A., Orita, I., Fukui, T., Suzuki, T., Yao, M., Tanaka, Y., Suzuki, T.
- Organizer
  19th RNA meeting
- Data Source
  KAKENHI-PROJECT-26702035
[Presentation] Biogenesis and physiological role of 5-formylcytidine in mammalian mitochondrial tRNAMet2017
- Author(s)
  Takeo Suzuki, Layla Kawarada, Saori Nakano, Takayuki Ohira, Hiroyoshi Iwata, Kana Asano, Shoji Hirata, Kenjyo Miyauchi, Tsutomu Suzuki
- Organizer
  19th RNA meeting
- Data Source
  KAKENHI-PROJECT-26702035
[Presentation] RNA-MSを用いたトリパノソーマmRNAおよびSL RNAにおける転写後修飾の解析2017
- Author(s)
  穐近慎一郎、松木美知枝、鈴木健夫、Ho Kiong、鈴木勉
- Organizer
  第17回東京大学生命科学シンポジウム
- Data Source
  KAKENHI-PROJECT-26702035
[Presentation] ALKBH1はミトコンドリアおよび細胞質tRNA修飾のジオキシゲナーゼとしてはたらく2017
- Author(s)
  川原田礼以良、鈴木健夫、大平高之、平田翔児、宮内健常、鈴木勉
- Organizer
  第17回東京大学生命科学シンポジウム
- Data Source
  KAKENHI-PROJECT-26702035
[Presentation] 哺乳類ミトコンドリアtRNAに存在する5-メチルシチジンの機能解析2017
- Author(s)
  北川翔、中野沙緒里、中川真一、荒木喜美、荒木正健、鈴木健夫、鈴木勉
- Organizer
  第17回東京大学生命科学シンポジウム
- Data Source
  KAKENHI-PROJECT-26702035
[Presentation] Biogenesis and function of N6-methyladenosine in U snRNAs2016
- Author(s)
  Ishigami, Y., Ohira, T., Akichika, S., Suzuki, T., Suzuki, T.
- Organizer
  RNA2016
- Place of Presentation
  Kyoto International Conference Center, Kyoto, Japan
- Year and Date
  2016-06-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26702035
[Presentation] Mass spectrometric characterization of post-transcriptional modifications in mRNAs and spliced-leader RNA from Trypanosoma brucei2016
- Author(s)
  Akichika, S., Matsuki, M., Suzuki, T., Ho, C. K., Suzuki, T.
- Organizer
  MBSJ2016
- Place of Presentation
  Pacifico Yokohama, Kanagawa, Japan
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26702035
[Presentation] Functional analysis of 5-methylcytidine in mammalian mitochondrial tRNA2016
- Author(s)
  Kitagawa, S., Nakano, S., Nakagawa, S., Suzuki, T., Araki, K., Araki, M., Suzuki, T.
- Organizer
  MBSJ2016
- Place of Presentation
  Pacifico Yokohama, Kanagawa, Japan
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26702035
[Presentation] Substrate recognition by NSUN3, an RNA methyltransferase which initiates 5-formylcytidine formation in human mitochondrial tRNAMet2016
- Author(s)
  In, S., Kawarada, L., Suzuki, T., Suzuki, T.
- Organizer
  MBSJ2016
- Place of Presentation
  Pacifico Yokohama, Kanagawa, Japan
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26702035
[Presentation] NSUN3 initiates formation of 5-formylcytidine, a post-transcriptional modification in human mitochondrial tRNAMet required to decipher non-universal genetic code2016
- Author(s)
  Nakano, S., Suzuki, T., Kawarada, L., Iwata, H., Asano, K., Suzuki, T.
- Organizer
  RNA2016
- Place of Presentation
  Kyoto International Conference Center, Kyoto, Japan
- Year and Date
  2016-06-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26702035
[Presentation] A complete landscape of post-transcriptional modifications in human mitochondrial tRNAs2016
- Author(s)
  Suzuki, T., Yashiro, Y., Asano, K., Lin, H., Kirino, Y., Sakaguchi, Y., Suzuki, T.
- Organizer
  RNA2016
- Place of Presentation
  Kyoto International Conference Center, Kyoto, Japan
- Year and Date
  2016-06-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26702035
[Presentation] Deficiency of tRNA modification causes the development of X-linked mental retardation2015
- Author(s)
  Fan-Yan Wei, Yu Nagayoshi, Shoji Hirata, Takeo Suzuki, Tsutomu Suzuki, Kazuhito Tomizawa
- Organizer
  第17回日本RNA学会年会
- Place of Presentation
  ホテルライフォート札幌、札幌市、北海道
- Year and Date
  2015-07-15
- Data Source
  KAKENHI-PROJECT-26702035
[Presentation] Biogenesis of 5-taurinomethyluridine in human mitochondrial tRNAs; implication for molecular pathogenesis of mitochondrial diseases2015
- Author(s)
  Kana Asano, Takeo Suzuki, Fan-Yan Wei, Yoshiho Ikeuchi, Yuka Yashiro, Christin Tischner, Annette Hofer, Yoshihito Kishita, Yasushi Okazaki, Tina Wenz, Kazuhito Tomizawa, Tsutomu Suzuki
- Organizer
  第17回日本RNA学会年会
- Place of Presentation
  ホテルライフォート札幌、札幌市、北海道
- Year and Date
  2015-07-15
- Data Source
  KAKENHI-PROJECT-26702035
[Presentation] Exploration and functional analysis of queuosine-glycosyltransferases in mammals2015
- Author(s)
  Xuewei Zhao, Takeo Suzuki, Tsutomu Suzuki
- Organizer
  第17回日本RNA学会年会
- Place of Presentation
  ホテルライフォート札幌、札幌市、北海道
- Year and Date
  2015-07-15
- Data Source
  KAKENHI-PROJECT-26702035
[Presentation] Exploration and functional analysis of queuosine- glycosyltransferases in mammals2015
- Author(s)
  Xuewei Zhao, Takeo Suzuki, Tsutomu Suzuki
- Organizer
  第17回日本RNA学会年会
- Place of Presentation
  ホテルライフォート札幌, 札幌市, 北海道
- Year and Date
  2015-07-15
- Data Source
  KAKENHI-PROJECT-26560442
[Presentation] Deficiency of tRNA modification causes the development of X-linked mental retardation2015
- Author(s)
  Fan-Yan Wei, Yu Nagayoshi, Shoji Hirata, Takeo Suzuki, Tsutomu Suzuki, Kazuhito Tomizawa
- Organizer
  第17回日本RNA学会年会
- Place of Presentation
  ホテルライフォート札幌, 札幌市, 北海道
- Year and Date
  2015-07-15
- Data Source
  KAKENHI-PROJECT-26560442
[Presentation] Biogenesis of 5-taurinomethyluridine in human mitochondrial tRNAs; implication for molecular pathogenesis of mitochondrial diseases2015
- Author(s)
  Kana Asano, Takeo Suzuki, Fan-Yan Wei, Yoshiho Ikeuchi, Yuka Yashiro, Christin Tischner, Annette Hofer, Yoshihito Kishita, Yasushi Okazaki, Tina Wenz, Kazuhito Tomizawa, Tsutomu Suzuki
- Organizer
  第17回日本RNA学会年会
- Place of Presentation
  ホテルライフォート札幌, 札幌市, 北海道
- Year and Date
  2015-07-15
- Data Source
  KAKENHI-PROJECT-26560442
[Presentation] U snRNAにおけるN6-メチルアデノシン修飾の生合成と機能解析2015
- Author(s)
  石神宥真、大平高之、穐近慎一郎、鈴木健夫、鈴木勉
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド、神戸市、兵庫県
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26702035
[Presentation] U snRNAにおけるN6-メチルアデノシン修飾の生合成と機能解析2015
- Author(s)
  石神宥真、大平高之、穐近慎一郎、鈴木健夫、鈴木勉
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド, 神戸市, 兵庫県
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26560442
[Presentation] Sensitive measurement of tRNA 2-methylthio modification by quantitative PCR for clinical assessment of type 2 diabetes risk2013
- Author(s)
  Fan-Yan Wei, Peiyu Xie, Shoji Hirata, Taku Kaitsuka, Tsutomu Suzuki, Kazuhito Tomizawa, Takeo Suzuki
- Organizer
  15th RNA meeting
- Place of Presentation
  Himegin Hall, Ehime
- Data Source
  KAKENHI-PLANNED-21115003
[Presentation] Molecular pathogenesis of non-syndromic X-linked intellectual disability caused by a loss-of-function mutation in FTSJ12013
- Author(s)
  Shoji Hirata, Takeo Suzuki, Kenjyo Miyauchi, Yuichi Goto, Tsutomu Suzuki
- Organizer
  MBSJ2013
- Place of Presentation
  Kobe Port Island, Hyogo
- Data Source
  KAKENHI-PLANNED-21115003
[Presentation] Novel modified nucleoside found in 16S rRNA from halophilic archaea2013
- Author(s)
  Takeo Suzuki, Hajime Takeda, Tomoyuki Watanabe, Naoki Uchiyama, Takeshi Wada, Tsutomu Suzuki
- Organizer
  MBSJ2013
- Place of Presentation
  Kobe, Japan
- Data Source
  KAKENHI-PLANNED-21115003
[Presentation] Mechanistic insights into the functional role of the RlmE-mediated Um2552 formation in the late assembly of 50S subunit in Escherichia coli2013
- Author(s)
  Taiga Arai, Satoshi Kimura, Yuriko Sakaguchi, Takeo Suzuki and Tsutomu Suzuki
- Organizer
  15th RNA meeting
- Place of Presentation
  Himegin Hall, Ehime
- Data Source
  KAKENHI-PLANNED-21115003
[Presentation] Functional analysis of a 2?-5 ?RNA ligase from the Hyperthermophilc archaeon Thermococcus kodakarensis2013
- Author(s)
  Akira Hirata, Tomoko Nagano, Yuki Ishimaru, Tamotsu Kanai, Takeo Suzuki, Asako Sato, Akio Kanai, Tsutomu Suzuki, Hori Hiroyuki
- Organizer
  15th RNA meeting
- Place of Presentation
  Himegin Hall, Ehime
- Data Source
  KAKENHI-PLANNED-21115003
[Presentation] Novel modified nucleoside found in 16S rRNA from halophilic archaea2013
- Author(s)
  Takeo Suzuki, Hajime Takeda, Tomoyuki Watanabe, Naoki Uchiyama, Takeshi Wada, Tsutomu Suzuki
- Organizer
  MBSJ2013
- Place of Presentation
  Kobe Port Island, Hyogo
- Invited
- Data Source
  KAKENHI-PLANNED-21115003
[Presentation] Alternative pathway of tRNA maturation in Saccharomyces cerevisiae2012
- Author(s)
  Takayuki Ohira, Kenjyo Miyauchi, Yuriko Sakaguchi, Takeo Suzuki, Tsutomu Suzuki
- Organizer
  The 24th tRNA conference
- Place of Presentation
  Olmue, Chile
- Year and Date
  2012-12-02
- Data Source
  KAKENHI-PLANNED-21115003
[Presentation] The acetylation of 18S rRNA is an essential modification to synthesize the small subunit of ribosome in Saccharomyces cerevisiae2012
- Author(s)
  Satoshi Ito, Yu Akamatsu, Akiko Noma, Satoshi Kimura, Yoshiho Ikeuchi, Kenjyo Miyauchi, Yoshikazu Tanaka, Isao Tanaka, Takeo Suzuki, Tsutomu Suzuki
- Organizer
  The 9th International Conference on Ribosome Synthesis
- Place of Presentation
  Banff, Canada
- Year and Date
  2012-08-22
- Data Source
  KAKENHI-PLANNED-21115003
[Presentation] Insights into the functional role of the RlmE-mediated Um2552 formation in the late assembly of 50S subunit in Escherichia coli2012
- Author(s)
  Taiga Arai, Satoshi Kimura, Yuriko Sakaguchi, Takeo Suzuki, Tsutomu Suzuki
- Organizer
  The 9th International Conference on Ribosome Synthesis
- Place of Presentation
  Banff, Canada
- Year and Date
  2012-08-20
- Data Source
  KAKENHI-PLANNED-21115003
[Presentation] Native chemical structures of Escherichia coli tRNAs determined by mass spectrometric analysis2011
- Author(s)
  Kenjyo Miyauchi, Satoshi Kimura, Yuriko Sakaguchi, Takeo Suzuki, Tsutomu Suzuki
- Organizer
  MBSJ2011
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PLANNED-21115003
[Presentation] Biochemical characterization of 40S intermediate in the assembly of 50S ribosomal subunit in Escherichia coli2011
- Author(s)
  Taiga Arai, Satishi Kimura, Yuriko Sakaguchi, Takeo Suzuki, Tsutomu Suzuki
- Organizer
  MBSJ2011
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PLANNED-21115003
[Presentation] Crystal structure of dihydrouridine synthase in complex with RNA reveals its tRNA recognition and reaction mechanisms2011
- Author(s)
  Yoshikazu Tanaka, Futao Yu, Keitaro Yamashita, Akiyoshi Nakamura, Takeo Suzuki, Nagisa Hirano, Tsutomu Suzuki, Min Yao, Isao Tanaka
- Organizer
  RNA2011Kyoto
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-23710265
[Presentation] The acetylation of 18S rRNA is an essential modification to synthesize the small subunit of ribosome in Saccharomyces cerevisiae2011
- Author(s)
  Satoshi Ito, Yu Akamatsu, Akiko Noma, Satoshi Kimura, Yoshiho Ikeuchi, Keniyo Miyauchi, Yoshikazu Tanaka, Isao Tanaka, Takeo Suzuki, Tsutomu Suzuki
- Organizer
  MBSJ2011
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PLANNED-21115003
[Presentation] Base Methylations in the Double-stranded RNA by a Fused Methyltransferase Bearing Unwinding Activity2011
- Author(s)
  Satoshi Kimura, Yoshiho Ikeuchi, Kei Kitahara, Yuriko Sakaguchi, Takeo Suzuki, Tsutomu Suzuki
- Organizer
  RNA2011Kyoto
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-23710265
[Presentation] Unique characteristics of ascidian mitochondrial tRNAs : Existence of 5-t aurinomethyluridine-containing tRNAs involved in deciphering the non-universal genetic codes and an initiator tRNA corresponding to AUG codon2011
- Author(s)
  Takeo Suzuki, Kenjyo Miyauchi, Shin-ichi Yokobori, Naoki Shigi, Akiko Kondow, Nono Takeuchi, Tsutomu Suzuki, Akihiko Yamagishi, Kimitsuna Watanabe
- Organizer
  RNA2011Kyoto
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PLANNED-21115003
[Presentation] Unique characteristics of ascidian mitochondrial tRNAs: Existence of 5-taurinomethyluridine-containing tRNAs involved in deciphering the non-universal genetic codes and an initiator tRNA corresponding to AUG codon2011
- Author(s)
  Takeo Suzuki, Kenjyo Miyauchi, Shin-ichi Yokobori, Naoki Shigi, Akiko Kondow, Nono Takeuchi, Tsutomu Suzuki, Akihiko Yamagishi, Kimitsuna Watanabe
- Organizer
  RNA2011Kyoto
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-23710265
[Presentation] Necessity of tRNA introns for yeast growth2011
- Author(s)
  Shunsuke Mori, Toshiya Endo, Takeo Suzuki, Tsutomu Suzuki, Tohru Yoshihisa
- Organizer
  RNA2011Kyoto
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PLANNED-21115003
[Presentation] Necessity of tRNA introns for yeast growth2011
- Author(s)
  Shunsuke Mori, Toshiya Endo, Takeo Suzuki, Tsutomu Suzuki, Tohru Yoshihisa
- Organizer
  RNA2011Kyoto
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-23710265
[Presentation] Characterization of Human Homologues of MnmE and GidA, Required for an xm5U-type Uridine Modification at the Wobble Position of Mitochondrial tRNAs2011
- Author(s)
  Takeo Suzuki et al
- Organizer
  RNA2011Kyoto
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-23710265
[Presentation] In Vivo Reversal of a UV-induced Lesion on Mouse 28S rRNA2011
- Author(s)
  Atsumi Miyata, Makoto Kitabatake, Takeo Suzuki, Tsutomu Suzuki, Tomoko Sakata, Yohei Kobayashi, Shin Yonehara, Mutsuhito Ohno
- Organizer
  RNA2011Kyoto
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-23710265
[Presentation] Characterization of Human Homologues of MnmE and GidA, Required for an xm5U-type Uridine Modification at the Wobble Position of Mitochondrial tRNAs2011
- Author(s)
  Takeo Suzuki, Hirosi Sakai, Tomoyuki Numata, Takuo Osawa, Tsutomu Suzuki
- Organizer
  RNA2011Kyoto
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PLANNED-21115003
[Presentation] Native chemical structures of Escherichia coli tRNAs determined by mass spectrometric analysis2011
- Author(s)
  Kenjyo Miyauchi，Satoshi Kimura，Yuriko Sakaguchi，Takeo Suzuki，Tsutomu Suzuki
- Organizer
  MBSJ2011
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-23710265
[Presentation] The third pathway of tRNA export requires the retrograde import of precursor tRNA from cytoplasm to nucleus for its maturation in Saccharomyces cerevisiae2011
- Author(s)
  Takayuki Ohira，Kenjyo Miyauchi，Yuriko Sakaguchi，Takeo Suzuki，Tsutomu Suzuki
- Organizer
  MBSJ2011
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-23710265
[Presentation] The third pathway of tRNA export requires the retrograde import of precursor tRNA from cytoplasm to nucleus for its maturation in Saccharomyces cerevisiae2011
- Author(s)
  Takayuki Ohira, Keniyo Miyauchi, Yuriko Sakaguchi, Takeo Suzuki, Tsutomu Suzuki
- Organizer
  MBSJ2011
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PLANNED-21115003
[Presentation] In Vivo Reversal of a UV-induced Lesion on Mouse 28S rRNA2011
- Author(s)
  Atsumi Miyata, Makoto Kitabatake, Takeo Suzuki, Tsutomu Suzuki, Tomoko Sakata, Yohei Kobayashi, Shin Yonehara, Mutsuhito Ohno
- Organizer
  RNA2011Kyoto
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PLANNED-21115003
[Presentation] Base methylations in the double-stranded RNA by a fused methyltransferase bearing unwinding activity in ribosome assembly2011
- Author(s)
  Satoshi Kimura，Yoshiho Ikeuchi，Kei Kitahara，Yuriko Sakaguchi，Takeo Suzuki，Tsutomu Suzuki
- Organizer
  MBSJ2011
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-23710265
[Presentation] Crystal structure of dihydrouridine synthase in complex with RNA reveals its tRNA recognition and reaction mechanisms2011
- Author(s)
  Yoshikazu Tanaka, Futao Yu, Keitaro Yamashita, Akiyoshi Nakamura, Takeo Suzuki, Nagisa Hirano, Tsutomu Suzuki, Min Yao, Isao Tanaka
- Organizer
  RNA2011Kyoto
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PLANNED-21115003
[Presentation] Base methylations in the double-stranded RNA by a fused methyltransferase bearing unwinding activity in ribosome assembly2011
- Author(s)
  Satoshi Kimura, Yoshiho Ikeuchi, Kei Kitahara, Yuriko Sakaguchi, Takeo Suzuki, Tsutomu Suzuki
- Organizer
  MBSJ2011
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PLANNED-21115003
[Presentation] Base Methylations in the Double-stranded RNA by a Fused Methyltransferase Bearing Unwinding Activity2011
- Author(s)
  Satoshi Kimura, Yoshiho Ikeuchi, Kei Kitahara, Yuriko Sakaguchi, Takeo Suzuki, Tsutomu Suzuki
- Organizer
  RNA2011Kyoto
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PLANNED-21115003
[Presentation] Biochemical characterization of 40S intermediate in the assembly of 50S ribosomal subunit in Escherichia coli2011
- Author(s)
  Taiga Arai, Satishi Kimura, Yuriko Sakaguchi, Takeo Suzuki and Tsutomu Suzuki
- Organizer
  MBSJ2011
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-23710265
[Presentation] The acetylation of 18S rRNA is an essential modification to synthesize the small subunit of ribosome in Saccharomyces cerevisiae2011
- Author(s)
  Satoshi Ito，Yu Akamatsu，Akiko Noma，Satoshi Kimura，Yoshiho Ikeuchi，Kenjyo Miyauchi，Yoshikazu Tanaka，Isao Tanaka，Takeo Suzuki，Tsutomu Suzuki
- Organizer
  MBSJ2011
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-23710265
[Presentation] Requirements for in vitro formation of 5-carboxymethylaminometyluri dine at the wobble position in Escherichia coli tRNAs2010
- Author(s)
  Suzuki, T., et al.
- Organizer
  23rd tRNA workshop
- Place of Presentation
  Aveiro, Portugal
- Data Source
  KAKENHI-PLANNED-21115003
[Presentation] Biosynthetic mechanism and substrate recognition by modification enzymes of the wobble xm5-modified uridine in Escherichia coli2010
- Author(s)
  Suzuki, T., et al.
- Organizer
  BMB2010
- Place of Presentation
  Kobe, Japan
- Data Source
  KAKENHI-PLANNED-21115003
[Presentation] Requirements for in vitro formation of 5-carboxymethylaminometyluridine at the wobble position in Escherichia coli tRNAs2009
- Author(s)
  Suzuki, T., et al.
- Organizer
  32nd MBSJ
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PLANNED-21115003
[Presentation] Analysis of the functional role of FTSJ1 related to non-syndromic X-linked intellectual disability
- Author(s)
  Shoji Hirata, Takeshi Chujo, Takeo Suzuki, Kenjyo Miyauchi, Yuichi Goto, Tsutomu Suzuki
- Organizer
  第16回日本RNA学会年会
- Place of Presentation
  ウインクあいち、名古屋市、愛知県
- Year and Date
  2014-07-23 – 2014-07-25
- Data Source
  KAKENHI-PROJECT-26702035
[Presentation] Analysis of the functional role of FTSJ1 related to non-syndromic X-linked intellectual disability
- Author(s)
  Shoji Hirata, Takeshi Chujo, Takeo Suzuki, Kenjyo Miyauchi, Yuichi Goto, Tsutomu Suzuki
- Organizer
  第16回日本RNA学会年会
- Place of Presentation
  ウインクあいち、名古屋市、愛知県
- Year and Date
  2014-07-23 – 2014-07-25
- Data Source
  KAKENHI-PROJECT-26560442
[Presentation] ミトコンドリアtRNAタウリン修飾の生合成と機能
- Author(s)
  鈴木健夫、浅野奏、魏范研、富澤一仁、池内与志穂、鈴木勉
- Organizer
  第14回日本ミトコンドリア学会年会
- Place of Presentation
  九大医百年講堂、福岡市、福岡県
- Year and Date
  2014-12-03 – 2014-12-05
- Data Source
  KAKENHI-PROJECT-26702035
[Presentation] Alternative pathway of tRNA maturation in Saccharomyces cerevisiae
- Author(s)
  Takayuki Ohira, Kenjyo Miyauchi, Yuriko Sakaguchi, Takeo Suzuki, Tsutomu Suzuki
- Organizer
  The 24th tRNA conference
- Place of Presentation
  Olmue, Chile
- Data Source
  KAKENHI-PROJECT-23710265
[Presentation] A complete landscape of post-transcriptional modifications in mammalian mitochondrial tRNAs
- Author(s)
  Suzuki, T. and Suzuki, T.
- Organizer
  The 25th tRNA conference
- Place of Presentation
  Kyllini, Greece
- Year and Date
  2014-09-21 – 2014-09-25
- Data Source
  KAKENHI-PROJECT-26702035
[Presentation] ミトコンドリアtRNAタウリン修飾の生合成と機能
- Author(s)
  鈴木健夫、浅野奏、魏范研、富澤一仁、池内与志穂、鈴木勉
- Organizer
  第14回日本ミトコンドリア学会年会
- Place of Presentation
  九大医百年講堂、福岡市、福岡県
- Year and Date
  2014-12-03 – 2014-12-05
- Data Source
  KAKENHI-PROJECT-26560442
[Presentation] 哺乳類ミトコンドリアにおけるtRNA48位の5-メチルシチジン修飾酵素の同定
- Author(s)
  中野紗緒里、鈴木健夫、荒木喜美、荒木正健、鈴木勉
- Organizer
  第14回日本ミトコンドリア学会年会
- Place of Presentation
  九大医百年講堂、福岡市、福岡県
- Year and Date
  2014-12-03 – 2014-12-05
- Data Source
  KAKENHI-PROJECT-26560442
[Presentation] The acetylation of 18S rRNA is an essential modification to synthesize the small subunit of ribosome in Saccharomyces cerevisiae
- Author(s)
  Satoshi Ito, Yu Akamatsu, Akiko Noma, Satoshi Kimura, Yoshiho Ikeuchi, Kenjyo Miyauchi, Yoshikazu Tanaka, Isao Tanaka, Takeo Suzuki, Tsutomu Suzuki
- Organizer
  The 9th International Conference on Ribosome Synthesis
- Place of Presentation
  Banff, Canada
- Data Source
  KAKENHI-PROJECT-23710265
[Presentation] 哺乳類ミトコンドリアにおけるtRNA48位の5-メチルシチジン修飾酵素の同定
- Author(s)
  中野紗緒里、鈴木健夫、荒木喜美、荒木正健、鈴木勉
- Organizer
  第14回日本ミトコンドリア学会年会
- Place of Presentation
  九大医百年講堂、福岡市、福岡県
- Year and Date
  2014-12-03 – 2014-12-05
- Data Source
  KAKENHI-PROJECT-26702035
[Presentation] Mitochondrial disease as the first instance of RNA modopathy
- Author(s)
  Takeo Suzuki, Kana Asano, Fan-Yan Wei, Kazuhito Tomizawa, Tsutomu Suzuki
- Organizer
  第16回日本RNA学会年会
- Place of Presentation
  ウインクあいち、名古屋市、愛知県
- Year and Date
  2014-07-23 – 2014-07-25
- Invited
- Data Source
  KAKENHI-PROJECT-26702035
[Presentation] Mitochondrial disease as the first instance of RNA modopathy
- Author(s)
  Takeo Suzuki, Kana Asano, Fan-Yan Wei, Kazuhito Tomizawa, Tsutomu Suzuki
- Organizer
  第16回日本RNA学会年会
- Place of Presentation
  ウインクあいち、名古屋市、愛知県
- Year and Date
  2014-07-23 – 2014-07-25
- Invited
- Data Source
  KAKENHI-PROJECT-26560442
[Presentation] Insights into the functional role of the RlmE-mediated Um2552 formation in the late assembly of 50S subunit in Escherichia coli
- Author(s)
  Taiga Arai, Satoshi Kimura, Yuriko Sakaguchi, Takeo Suzuki, Tsutomu Suzuki
- Organizer
  The 9th International Conference on Ribosome Synthesis
- Place of Presentation
  Banff, Canada
- Data Source
  KAKENHI-PROJECT-23710265
[Presentation] A complete landscape of post-transcriptional modifications in mammalian mitochondrial tRNAs
- Author(s)
  Suzuki, T. and Suzuki, T.
- Organizer
  The 25th tRNA conference
- Place of Presentation
  Kyllini, Greece
- Year and Date
  2014-09-21 – 2014-09-25
- Data Source
  KAKENHI-PROJECT-26560442

1. TOMARI Yukihide (90447368)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
2. KAGEYAMA Yuji (90335480)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. TEI Kumiko (50213327)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. NAKAZAWA Takanobu (00447335)

# of Collaborated Projects: 1 results

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5. WADA Takeshi (90240548)

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# of Collaborated Products: 1 results
6. SADO Takashi (70321601)

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# of Collaborated Products: 1 results
7. SIOMI Mikiko (20322745)

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8. MIYAGAWA Satomi (90291153)

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9. NAKAGAWA Shinichi (50324679)

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10. TAKESHITA Fumitaka (40466199)

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11. ODA Takeaki (00608523)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
12. YAMASHITA Akio (20405020)

# of Collaborated Projects: 1 results

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13. NISHIMURA Yukiko (30514567)

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14. TAKEMOTO Chi (40306527)

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15. 尾山大明 (30422398)

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16. 秦裕子 (80401256)

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17. 佐藤香織 (00598344)

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18. 辻瑞樹 (20222135)

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19. 佐藤行人 (20566418)

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20. MICHIUE Hiroyuki

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# of Collaborated Products: 1 results
21. YOSHIMOTO Rei

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# of Collaborated Products: 1 results
22. TSUKAMOTO Osamu

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# of Collaborated Products: 1 results
23. 富澤一仁

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# of Collaborated Products: 1 results
24. 松井秀樹

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# of Collaborated Products: 1 results
25. 広瀬豊

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# of Collaborated Products: 1 results
26. 吉久徹

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# of Collaborated Products: 1 results
27. 横山武司

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28. 田中茂幸

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# of Collaborated Products: 1 results
29. 平田章

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# of Collaborated Products: 1 results
30. 鈴木勉

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# of Collaborated Products: 4 results
31. 新谷泰範

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# of Collaborated Products: 1 results
32. 田中良和

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33. 池内与志穂

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34. 倉持敏美

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SUZUKI Takeo 鈴木 健夫

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哺乳類に固有なRNA修飾因子による組織特異的な機能発現メカニズムの探求Principal Investigator

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外来魚が水中に放出する化学物質が在来生態系を崩壊させる: 新仮説検証と物質同定

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ヒトに特有な希少RNA修飾の分子・生理機能の探求Principal Investigator

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Mechanistic elucidation of non-domain type biopolymer modifications

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Biosynthesis and function of a novel tRNA modification ectopically acquired by a disease associated mutationPrincipal Investigator

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Research for an mRNA modication specific to vertebratesPrincipal Investigator

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Function and dynamic regulation of animal specific RNA modificationsPrincipal Investigator

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Exploring RNA modifications using enzymatic probe and its applicationsPrincipal Investigator

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Biosynthesis and function of characteristic RNA modifications found in humanPrincipal Investigator

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Biosynthetic mechanism of the wobble modified uridines in tRNAPrincipal Investigator

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Structural bases for an expanded codon recognition by modified nucleotide.

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Functional machinery for non-coding RNAs

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Structural and functional analysis of non-coding RNA machineriesPrincipal Investigator

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SUZUKI Takeo 鈴木健夫