KADOMATSU TSUYOSHI 門松毅

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KADOMATSU Tsuyoshi 門松毅

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Researcher Number	90555757
Other IDs
Affiliation (Current)	2025: 熊本大学, 大学院生命科学研究部(医), 講師
Affiliation (based on the past Project Information) *help	2020 – 2024: 熊本大学, 大学院生命科学研究部(医), 講師 2015 – 2019: 熊本大学, 大学院生命科学研究部(医), 助教 2013 – 2014: 熊本大学, 大学院生命科学研究部, 助教 2013: 熊本大学, 生命科学研究部, 助教 2011: 熊本大学, 大学院・生命科学研究部, 助教 2010 – 2011: 熊本大学, 生命科学研究部, 助教
Review Section/Research Field	Principal Investigator Basic Section 50010:Tumor biology-related / Biological Sciences / Tumor biology / Tumor diagnostics / Pathological medical chemistry Except Principal Investigator Metabolomics
Keywords	Principal Investigator ANGPTL2 / 腎細胞がん / ウイルス性肝炎 / 肝細胞がん / 免疫逃避 / がん免疫逃避 / 稀少腎細胞がん / 転座型腎細胞がん / TFE3融合遺伝子 / がん免疫 … More / miRNA / 尿中バイオマーカー / 免疫 / 老化 / 二次リンパ組織 / がん制御遺伝子 / 転座 / 希少がん / 骨肉腫 / がん微小環境 / 転写制御 / 稀少がん / 転移 / 発現制御 / エピゲノム / 生活習慣病 / 癌 / 慢性炎症 / 時計遺伝子 / 概日リズム / 転写調節 / Angpt12 / 分子病態学 … More Except Principal Investigator グルコキナーゼ / インスリン / HNF / MODY / 転写因子 / インスリン分泌 / 糖尿病 Less

ウイルス性肝炎増悪-肝細胞がん発症の新規分子機構解明に基づく予防・治療戦略の創出Principal Investigator
- Principal Investigator
  
  門松毅
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kumamoto University
Basic research for developing the therapeutic strategies for rare kidney cancer based on elucidation of novel mechanisms of tumor immune evasionPrincipal Investigator
- Principal Investigator
  
  Kadomatsu Tsuyoshi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kumamoto University
Basic research for the development of personalized therapeutic strategies against a rare renal cell carcinomaPrincipal Investigator
- Principal Investigator
  
  KADOMATSU Tsuyoshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kumamoto University
Elucidation of molecular mechanisms underlying development and progression of rare cancers caused by alteration of transcriptional regulationPrincipal Investigator
- Principal Investigator
  
  Kadomatsu Tsuyoshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  Kumamoto University
加齢に伴う二次リンパ組織内細胞間相互作用の変容による疾患発症の分子機構解明Principal Investigator
- Principal Investigator
  
  門松毅
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kumamoto University
Molecular mechanism of diabetes mellitus based on beta-cell transcription factor network
- Principal Investigator
  
  Yamagata Kazuya
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  Kumamoto University
Epigenetic regulation of ANGPTL2 expression in cancer and lifestyle diseasePrincipal Investigator
- Principal Investigator
  
  KADOMATSU Tsuyoshi
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor diagnostics
- Research Institution
  Kumamoto University
Analyses of the transcriptional regulatory mechanisms of chronic inflammation-related factor Angptl2Principal Investigator
- Principal Investigator
  
  KADOMATSU Tsuyoshi
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kumamoto University

[Book] 実験医学増刊　ミトコンドリア疾患治療の新時代　ミトコンドリア機能恒常性維持の変容と加齢関連疾患2023
- Author(s)
  門松　毅、尾池雄一
- Total Pages
  6
- Publisher
  羊土社
- ISBN
  9784758104098
- Data Source
  KAKENHI-PROJECT-21K07101
[Book] 実験医学別冊　論文図法を読む作法　細胞外フラックス解析2022
- Author(s)
  門松　毅、尾池雄一
- Total Pages
  3
- Publisher
  羊土社
- ISBN
  9784758122603
- Data Source
  KAKENHI-PROJECT-21K07101
[Book] Precision Medicine　アンチエイジング科学と未来医療　心不全とRNA創薬2022
- Author(s)
  門松　毅、尾池雄一
- Total Pages
  4
- Publisher
  北隆館
- Data Source
  KAKENHI-PROJECT-21K07101
[Book] Geriatric Medicine、エネルギー代謝の変容・破綻と加齢疾患2021
- Author(s)
  門松　毅、尾池雄一
- Publisher
  ライフ・サイエンス社
- Data Source
  KAKENHI-PROJECT-21K07101
[Book] 別冊Bio Clinica　慢性炎症と疾患、老化と慢性炎症、老化における慢性炎症とサルコペニア2021
- Author(s)
  門松　毅
- Publisher
  北隆館
- Data Source
  KAKENHI-PROJECT-21K07101
[Book] 日本抗加齢医学会雑誌アンチ・エイジング医学、　抗慢性炎症とミトコンドリア恒常性による健康長寿戦略2021
- Author(s)
  門松　毅、尾池雄一
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-21K07101
[Book] アンチ・エイジング医学　特集老化と炎症　5. 慢性炎症とサルコペニア2019
- Author(s)
  門松　毅
- Total Pages
  115
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-18K07236
[Book] 血管医学　特集：臓器の記憶と血管代謝ニッシェ2015
- Author(s)
  門松　毅、尾池雄一
- Total Pages
  112
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-15K06836
[Book] サイトカイン・増殖因子キーワード事典2015
- Author(s)
  門松　毅、尾池雄一
- Total Pages
  420
- Publisher
  羊土社
- Data Source
  KAKENHI-PUBLICLY-15H01159
[Book] サイトカイン・増殖因子キーワード事典2015
- Author(s)
  門松　毅、尾池雄一
- Total Pages
  420
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-15K06836
[Book] 別冊 BIO Clinica 慢性炎症と疾患「慢性炎症制御による加齢関連疾患治療の展望」2015
- Author(s)
  門松　毅、尾池雄一
- Total Pages
  170
- Publisher
  北隆館
- Data Source
  KAKENHI-PUBLICLY-15H01159
[Book] アンチ・エイジング医学2011
- Author(s)
  門松毅
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-22790322
[Book] アンチ・エイジング医学2011
- Author(s)
  門松毅, 尾池雄一
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-22790322
[Book] 実験医学増刊2011
- Author(s)
  門松毅
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-22790322
[Book] 実験医学増刊2011
- Author(s)
  門松毅, 浦上将太, 尾池雄一
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-22790322
[Book] 実験医学2010
- Author(s)
  門松毅
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-22790322
[Book] 実験医学2010
- Author(s)
  門松毅, 尾池雄一
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-22790322
[Journal Article] Tumor stroma-derived ANGPTL2 potentiates immune checkpoint inhibitor efficacy2024
- Author(s)
  Horiguchi Haruki、Kadomatsu Tsuyoshi、Yamashita Tomoya、Yumoto Shinsei、Horino Taichi、Sato Michio、Terada Kazutoyo、Miyata Keishi、Ichigozaki Yuki、Kimura Toshihiro、Fukushima Satoshi、Moroishi Toshiro、Oike Yuichi
- Journal Title
  
  Cancer Gene Therapy
  
  Volume: Online ahead of print Issue: 6 Pages: 0-0
- DOI
  10.1038/s41417-024-00757-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16285, KAKENHI-PROJECT-22K08187, KAKENHI-PROJECT-23K06638, KAKENHI-PROJECT-23K07511, KAKENHI-PROJECT-21K07101, KAKENHI-PROJECT-21H04825
[Journal Article] ANGPTL2‐mediated epigenetic repression of MHC‐I in tumor cells accelerates tumor immune evasion2023
- Author(s)
  Kadomatsu Tsuyoshi、Hara Chiaki、Kurahashi Ryoma、Horiguchi Haruki、Morinaga Jun、Miyata Keishi、Kurano Sohtaro、Kanemaru Hisashi、Fukushima Satoshi、Araki Kimi、Baba Masaya、Linehan W. Marston、Kamba Tomomi、Oike Yuichi
- Journal Title
  
  Molecular Oncology
  
  Volume: 17 Issue: 12 Pages: 2637-2658
- DOI
  10.1002/1878-0261.13490
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08187, KAKENHI-PROJECT-23K06638, KAKENHI-PROJECT-21K07101, KAKENHI-PROJECT-21K08351, KAKENHI-PROJECT-21K19721, KAKENHI-PROJECT-22K19533, KAKENHI-PROJECT-20K16450, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-21H04825, KAKENHI-PROJECT-23K24474
[Journal Article] Steep increase in the number of transthyretin-positive cardiac biopsy cases in Japan: evidence obtained by the nation-wide pathology consultation for the typing diagnosis of amyloidosis2023
- Author(s)
  Naiki H, Yamaguchi A, Sekijima Y, Ueda M, Ohashi K, Hatakeyama K, Ikeda Y, Hoshii Y, Shintani-Domoto Y, Miyagawa-Hayashino A, Tsujikawa H, Endo J, Arai T, Ando Y.
- Journal Title
  
  Amyloid
  
  Volume: 30 Issue: 1 Pages: 321-326
- DOI
  10.1038/s42003-023-04680-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07528, KAKENHI-PROJECT-22K08187, KAKENHI-PROJECT-21K07101, KAKENHI-PROJECT-22K19533, KAKENHI-PROJECT-21H04825, KAKENHI-PROJECT-23K21370
[Journal Article] Efficacy and safety in mice of repeated, lifelong administration of an ANGPTL3 vaccine2023
- Author(s)
  Fukami Hirotaka、Morinaga Jun、Nakagami Hironori、Hayashi Hiroki、Okadome Yusuke、Matsunaga Eiji、Kadomatsu Tsuyoshi、Horiguchi Haruki、Sato Michio、Sugizaki Taichi、Miyata Keishi、Torigoe Daisuke、Mukoyama Masashi、Morishita Ryuichi、Oike Yuichi
- Journal Title
  
  npj Vaccines
  
  Volume: 8 Issue: 1 Pages: 168-168
- DOI
  10.1038/s41541-023-00770-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18291, KAKENHI-PROJECT-22K08187, KAKENHI-PROJECT-22K11727, KAKENHI-PROJECT-23K07511, KAKENHI-PROJECT-21K07101, KAKENHI-PROJECT-22K19533, KAKENHI-PROJECT-22K16429, KAKENHI-PROJECT-21H04825, KAKENHI-PROJECT-21H02827
[Journal Article] Increased numbers of pre-operative circulating monocytes predict risk of developing cardiac surgery-associated acute kidney injury in conditions requiring cardio pulmonary bypass.2023
- Author(s)
  Okadome Y, Morinaga J, Yamanouchi Y, Matsunaga E, Fukami H, Kadomatsu T, Horiguchi H, Sato M, Sugizaki T, Hayata M, Sakaguchi T, Hirayama R, Ishimura T, Kuwabara T, Usuku K, Yamamoto T,Mukoyama M, Suzuki R, Fukui T, and Oike Y
- Journal Title
  
  Clin Exp Nephrol
  
  Volume: 27 Issue: 4 Pages: 329-339
- DOI
  10.1007/s10157-022-02313-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07101, KAKENHI-PROJECT-22K08357, KAKENHI-PROJECT-22K19533, KAKENHI-PROJECT-22K16429, KAKENHI-PROJECT-21K16061, KAKENHI-PROJECT-21K20935, KAKENHI-PROJECT-23K18291
[Journal Article] ANGPTL2 promotes immune checkpoint inhibitor-related murine autoimmune myocarditis2023
- Author(s)
  Horiguchi Haruki、Kadomatsu Tsuyoshi、Yamashita Tomoya、Yumoto Shinsei、Terada Kazutoyo、Sato Michio、Morinaga Jun、Miyata Keishi、Oike Yuichi
- Journal Title
  
  Communications Biology
  
  Volume: 6 Issue: 1 Pages: 965-965
- DOI
  10.1038/s42003-023-05338-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08187, KAKENHI-PROJECT-23K06638, KAKENHI-PROJECT-23K07511, KAKENHI-PROJECT-21K07101, KAKENHI-PROJECT-22K19533, KAKENHI-PROJECT-21H04825
[Journal Article] Plasma ANGPTL8 Levels and Risk for Secondary Cardiovascular Events in Japanese Patients With Stable Coronary Artery Disease Receiving Statin Therapy2023
- Author(s)
  Morinaga Jun、Mukoyama Masashi、Oike Yuichi、et al.
- Journal Title
  
  Arteriosclerosis, Thrombosis, and Vascular Biology
  
  Volume: 43 Issue: 8 Pages: 1549-1559
- DOI
  10.1161/atvbaha.122.318880
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18291, KAKENHI-PROJECT-22K08187, KAKENHI-PROJECT-22K11727, KAKENHI-PROJECT-23K07511, KAKENHI-PROJECT-21K07101, KAKENHI-PROJECT-22K19533, KAKENHI-PROJECT-22K16429, KAKENHI-PROJECT-21H04825
[Journal Article] Tumor cell-derived ANGPTL2 promotes β-catenin-driven intestinal tumorigenesis.2022
- Author(s)
  1.Horiguchi H, Kadomatsu T, Yumoto S, Masuda T, Miyata K, Yamamura S, Sato M, Morinaga J, Ohtsuki S, Baba H, Moroishi T, and Oike Y
- Journal Title
  
  Oncogene
  
  Volume: 41 Issue: 33 Pages: 4208-4041
- DOI
  10.1038/s41388-022-02405-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07101, KAKENHI-PROJECT-22K08187, KAKENHI-PROJECT-22K19533, KAKENHI-PROJECT-21K15508, KAKENHI-PROJECT-21K16061
[Journal Article] Vaccine targeting ANGPTL3 ameliorates dyslipidemia and associated diseases in mouse models of obese dyslipidemia and familial hypercholesterolemia2021
- Author(s)
  Fukami Hirotaka、Morinaga Jun、Nakagami Hironori、Hayashi Hiroki、Okadome Yusuke、Matsunaga Eiji、Kadomatsu Tsuyoshi、Horiguchi Haruki、Sato Michio、Sugizaki Taichi、Kuwabara Takashige、Miyata Keishi、Mukoyama Masashi、Morishita Ryuichi、Oike Yuichi
- Journal Title
  
  Cell Reports Medicine
  
  Volume: 2 Issue: 11 Pages: 100446-100446
- DOI
  10.1016/j.xcrm.2021.100446
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08560, KAKENHI-PROJECT-19K08728, KAKENHI-PROJECT-20K17288, KAKENHI-PROJECT-21H04825, KAKENHI-PROJECT-20K08611, KAKENHI-PROJECT-21K07101, KAKENHI-PROJECT-21K15508, KAKENHI-PROJECT-21K16061, KAKENHI-PROJECT-21K20935
[Journal Article] Angiopoietin-like protein 2 decreases peritoneal metastasis of ovarian cancer cells by suppressing anoikis resistance.2021
- Author(s)
  Takeshita Y, Motohara T, Kadomatsu T, Doi T, Obayashi K, Oike Y, Katabuchi H, Endo M.
- Journal Title
  
  Biochem Bioph Res Commun
  
  Volume: 561 Pages: 26-32
- DOI
  10.1016/j.bbrc.2021.05.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04825, KAKENHI-PROJECT-19K09826, KAKENHI-PROJECT-20K08530, KAKENHI-PROJECT-20K09673, KAKENHI-PROJECT-21K07101, KAKENHI-PROJECT-20K18223
[Journal Article] The lncRNA Caren antagonizes heart failure by inactivating DNA damage response and activating mitochondrial biogenesis2021
- Author(s)
  Sato Michio, Kadomatsu Tsuyoshi, Miyata Keishi, Warren Junco S., Tian Zhe、Node Koichi、Araki Kimi、 Oike Yuichi et al
- Journal Title
  
  Nature Communications
  
  Volume: 12 Issue: 1 Pages: 2529-2529
- DOI
  10.1038/s41467-021-22735-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08560, KAKENHI-PROJECT-21H04825, KAKENHI-PROJECT-21K05999, KAKENHI-PROJECT-21K07101, KAKENHI-PROJECT-21K15508, KAKENHI-PROJECT-21K16061, KAKENHI-PROJECT-16H06276, KAKENHI-PLANNED-21H05274
[Journal Article] Serum anti-p53 autoantibodies in angiosarcoma.2020
- Author(s)
  Mihoko Kiyohara , Jun Aoi , Ikko Kajihara , Saki Otuka , Tuyoshi Kadomatsu , Satoshi Fukushima , Hironobu Ihn
- Journal Title
  
  Journal of Dermatology
  
  Volume: 47 Issue: 8 Pages: 849-854
- DOI
  10.1111/1346-8138.15416
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07236, KAKENHI-PROJECT-18K08301
[Journal Article] Tumor cell-derived angiopoietin-like protein 2 establishes a preference for glycolytic metabolism in lung cancer cells.2020
- Author(s)
  Osumi H, Horiguchi H, Kadomatsu T, Tashiro K, Morinaga J, Takahashi T, Ikeda K, Ito T, Suzuki M, Endo M, Oike Y
- Journal Title
  
  Cancer Sci
  
  Volume: - Issue: 4 Pages: 1241-1253
- DOI
  10.1111/cas.14337
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08663, KAKENHI-PROJECT-18K15246, KAKENHI-PROJECT-20K08530, KAKENHI-PROJECT-16H02468, KAKENHI-PROJECT-18H02809, KAKENHI-PROJECT-18K07236
[Journal Article] Stroma-derived ANGPTL2 establishes an anti-tumor microenvironment during intestinal tumorigenesis2020
- Author(s)
  Horiguchi Haruki、Kadomatsu Tsuyoshi、Miyata Keishi、Terada Kazutoyo、Sato Michio、Torigoe Daisuke、Morinaga Jun、Moroishi Toshiro、Oike Yuichi
- Journal Title
  
  Oncogene
  
  Volume: 40 Issue: 1 Pages: 55-67
- DOI
  10.1038/s41388-020-01505-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08560, KAKENHI-PROJECT-18H02809, KAKENHI-PROJECT-18K07236, KAKENHI-PROJECT-19K17607, KAKENHI-PROJECT-21H04825, KAKENHI-PROJECT-21K07101
[Journal Article] Roles of angiopoietin-like proteins in regulation of stem cell activity.2019
- Author(s)
  Kadomatsu T, Oike Y.
- Journal Title
  
  J. Biochem.
  
  Volume: 165 Issue: 4 Pages: 309-315
- DOI
  10.1093/jb/mvz005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07236, KAKENHI-PUBLICLY-17H05652, KAKENHI-PROJECT-18H02809
[Journal Article] Dual functions of angiopoietin-like protein 2 signaling in tumor progression and anti-tumor immunity.2019
- Author(s)
  Horiguchi H, Kadomatsu T, Kurahashi R, Hara C, Miyata K, Baba M, Osumi H, Terada K, Araki K, Takai T, Kamba T, Linehan WM, Moroishi T, Oike Y.
- Journal Title
  
  Genes Dev
  
  Volume: 33 Issue: 23-24 Pages: 1641-1656
- DOI
  10.1101/gad.329417.119
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07236, KAKENHI-PROJECT-19K08560, KAKENHI-PROJECT-18H02438, KAKENHI-PROJECT-18H02938, KAKENHI-PROJECT-18K19619, KAKENHI-PROJECT-18K15246
[Journal Article] TFE3 Xp11.2 translocation renal cell carcinoma mouse model reveals novel therapeutic targets and identifies GPNMB as a diagnostic marker for human disease.2019
- Author(s)
  Baba M, Furuya M, Motoshima T, Lang M, Funasaki S, Ma W, Sun HW, Hasumi H, Huang Y, Kato I, Kadomatsu T, Satou Y, Morris N, Karim BO, Ileva L, Kalen JD, Wilan Krisna LA, Hasumi Y, Sugiyama A, Kurahashi R, Nishimoto K, Oyama M, Nagashima Y, Kuroda N, Araki K, Eto M, Yao M, Kamba T, Suda T, Oike Y, Schmidt LS, Linehan WM
- Journal Title
  
  Molecular Cancer Research
  
  Volume: 印刷中 Issue: 8 Pages: 1613-1626
- DOI
  10.1158/1541-7786.mcr-18-1235
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19619, KAKENHI-PROJECT-18H02938, KAKENHI-PROJECT-18K07236, KAKENHI-PROJECT-19K09717, KAKENHI-PROJECT-18KK0230, KAKENHI-PROJECT-18H05284, KAKENHI-PROJECT-18H02809, KAKENHI-PROJECT-19J15484, KAKENHI-PROJECT-17K08745, KAKENHI-PROJECT-17K09016, KAKENHI-PROJECT-17K11162, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-19K09694
[Journal Article] MiR-204-5p: a novel candidate urinary biomarker of Xp11.2 translocation renal cell carcinoma.2019
- Author(s)
  Kurahashi R, Kadomatsu T, Baba M, Hara C, Itoh H, Miyata K, Endo M, Morinaga J, Terada K, Araki K, Eto M, Schmidt LS, Kamba T, Linehan WM, Oike Y.
- Journal Title
  
  Cancer Science
  
  Volume: 印刷中 Issue: 6 Pages: 1897-1908
- DOI
  10.1111/cas.14026
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19619, KAKENHI-PROJECT-18H02938, KAKENHI-PROJECT-18K07236, KAKENHI-PROJECT-19K08560, KAKENHI-PROJECT-18H02809, KAKENHI-PROJECT-17K08663, KAKENHI-PROJECT-18K19519
[Journal Article] Association of circulating ANGPTL 3, 4, and 8 levels with medical status in a population undergoing routine medical checkups: A cross-sectional study.2018
- Author(s)
  Morinaga J, Zhao J, Endo M, Kadomatsu T, Miyata K, Sugizaki T, Okadome Y, Tian Z, Horiguchi H, Miyashita K, Maruyama N, Mukoyama M, Oike Y.
- Journal Title
  
  PLoS One
  
  Volume: 13 Issue: 3 Pages: e0193731-e0193731
- DOI
  10.1371/journal.pone.0193731
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08663, KAKENHI-PROJECT-17K09706, KAKENHI-PROJECT-18K15246, KAKENHI-PROJECT-15K06836
[Journal Article] Circulating ANGPTL2 Levels Increase in Humans and Mice Exhibiting Cardiac Dysfunction2018
- Author(s)
  Tian Z, Miyata K, Morinaga J, Horiguchi H, Kadomatsu T, Endo M, Zhao J, Zhu S, Sugizaki T, Sato M, Terada K, Okumura T, Murohara T, Oike Y.
- Journal Title
  
  Circ J
  
  Volume: 82 Issue: 2 Pages: 437-447
- DOI
  10.1253/circj.CJ-17-0327
- NAID
  130006320284
- ISSN
  1346-9843, 1347-4820
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08663, KAKENHI-PROJECT-17F17121, KAKENHI-PROJECT-15K06836
[Journal Article] Angiopoietin-like protein 2 promotes chondrogenic differentiation during bone growth as a cartilage matrix factor.2018
- Author(s)
  Tanoue H, Morinaga J, Yoshizawa T, Yugami M, Itoh H, Nakamura T, Uehara Y, Masuda T, Odagiri H, Sugizaki T, Kadomatsu T, Miyata K, Endo M, Terada K, Ochi H, Takeda S, Yamagata K, Fukuda T, Mizuta H, Oike Y.
- Journal Title
  
  Osteoarthritis Cartilage
  
  Volume: 26 Issue: 1 Pages: 108-117
- DOI
  10.1016/j.joca.2017.10.011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08663, KAKENHI-PROJECT-16H05328, KAKENHI-PROJECT-15K06836
[Journal Article] Age-dependent increase in angiopoietin-like protein 2 accelerates skeletal muscle loss in mice.2018
- Author(s)
  Zhao J, Tian Z, Kadomatsu T, Xie P, Miyata K, Sugizaki T, Endo M, Zhu S, Fan H, Horiguchi H, Morinaga J, Terada K, Yoshizawa T, Yamagata K, Oike Y.
- Journal Title
  
  J Biol Chem
  
  Volume: 293 Issue: 5 Pages: 1596-1609
- DOI
  10.1074/jbc.m117.814996
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08663, KAKENHI-PUBLICLY-17H05652, KAKENHI-PROJECT-16H05328, KAKENHI-PROJECT-17F17121, KAKENHI-PROJECT-16K09504, KAKENHI-PROJECT-15K06836, KAKENHI-PROJECT-16K15445, KAKENHI-PROJECT-18K19519
[Journal Article] TET2-dependent IL-6 induction mediated by the tumor microenvironment promotes tumor metastasis in osteosarcoma.2018
- Author(s)
  Itoh H, Kadomatsu T, Tanoue H, Yugami M, Miyata K, Endo M, Morinaga J, Kobayashi E, Miyamoto T, Kurahashi R, Terada K, Mizuta H, Oike Y.
- Journal Title
  
  Oncogene
  
  Volume: 印刷中 Issue: 22 Pages: 2903-2920
- DOI
  10.1038/s41388-018-0160-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08663, KAKENHI-PUBLICLY-17H05652, KAKENHI-PROJECT-18H02930, KAKENHI-PROJECT-15K06836
[Journal Article] Treatment of diabetic mice with the SGLT2 inhibitor TA-1887 antagonizes diabetic cachexia and decreases mortality.2017
- Author(s)
  Sugizaki T, Zhu S, Guo G, Matsumoto A, Zhao J, Endo M, Horiguchi H, Morinaga J, Tian Z, Kadomatsu T, Miyata K, Itoh H, Oike Y
- Journal Title
  
  NPJ Aging Mech Dis
  
  Volume: 3 Issue: 1 Pages: 12-12
- DOI
  10.1038/s41514-017-0012-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08663, KAKENHI-PROJECT-15K06836
[Journal Article] ANGPTL2　― A New Causal Player in Accelerating Heart Disease Development in the Aging ―2017
- Author(s)
  Oike Y, Tian Z, Miyata K, Morinaga J, Endo M, Kadomatsu T.
- Journal Title
  
  Circ J
  
  Volume: 81 Issue: 10 Pages: 1379-1385
- DOI
  10.1253/circj.CJ-17-0854
- NAID
  130006099927
- ISSN
  1346-9843, 1347-4820
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08663, KAKENHI-PUBLICLY-17H05652, KAKENHI-PROJECT-15K06836, KAKENHI-PROJECT-16K15445
[Journal Article] ANGPTL2 expression in intestinal stem cell niche controls epithelial regeneration and homeostasis.2017
- Author(s)
  Horiguchi H, Endo M, Kawane K, Kadomatsu T, Terada K, Morinaga J, Araki K, Miyata K, Oike Y,
- Journal Title
  
  EMBO Journal
  
  Volume: 36 Issue: 4 Pages: 409-424
- DOI
  10.15252/embj.201695690
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01520, KAKENHI-PROJECT-15H06508, KAKENHI-PROJECT-26293190, KAKENHI-PROJECT-26713011, KAKENHI-PROJECT-16K07093, KAKENHI-PROJECT-15K06836
[Journal Article] Angiopoietin-like protein 2 increases renal fibrosis by accelerating transforming growth factor-β signaling in chronic kidney disease.2016
- Author(s)
  Jun Morinaga, Tsuyoshi Kadomatsu, Keishi Miyata, Motoyoshi Endo, Kazutoyo Terada, Zhe Tian, Taichi Sugizaki, Hiroki Tanigawa, Jiabin Zhao, Shunshun Zhu, Michio Sato, Kimi Araki, Ken-ichi Iyama, Kengo Tomita, Masashi Mukoyama, Kimio Tomita, Kenichiro Kitamura, Yuichi Oike
- Journal Title
  
  Kidney International
  
  Volume: 89 Issue: 2 Pages: 327-341
- DOI
  10.1016/j.kint.2015.12.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K06836, KAKENHI-PROJECT-15K09031, KAKENHI-PROJECT-26461226, KAKENHI-PUBLICLY-15H01520, KAKENHI-PUBLICLY-26116722, KAKENHI-PROJECT-25461192, KAKENHI-PROJECT-26860639, KAKENHI-PROJECT-26861112, KAKENHI-PROJECT-26293190, KAKENHI-PROJECT-25461114, KAKENHI-PROJECT-26670405
[Journal Article] Mice Deficient in Angiopoietin-like Protein 2 (Angptl2) Gene Show Increased Susceptibility to Bacterial Infection Due to Attenuated Macrophage Activity2016
- Author(s)
  Yugami M, Odagiri H, Endo M, Tsutsuki H, Fujii S, Kadomatsu T, Masuda T, Miyata K, Terada K, Tanoue H, Ito H, Morinaga J, Horiguchi H, Sugizaki T, Akaike T, Gotoh T, Takai T, Sawa T, Mizuta H, Oike Y
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 291 Issue: 36 Pages: 18843-18852
- DOI
  10.1074/jbc.m116.720870
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01159, KAKENHI-PUBLICLY-15H01520, KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-26111008, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-15H06508, KAKENHI-PROJECT-26293190, KAKENHI-PROJECT-15K20008, KAKENHI-PROJECT-15K08456, KAKENHI-PROJECT-16K15208
[Journal Article] Macrophage-derived angiopoietin-like protein 2 exacerbates brain damage by accelerating acute inflammation after ischemia-reperfusion.2016
- Author(s)
  Amadatsu T, Morinaga J, Kawano T, Terada K, Kadomatsu T, Miyata K, Endo M, Kasamo D, Kuratsu JI & Oike Y
- Journal Title
  
  PLOS ONE
  
  Volume: 11 Issue: 11 Pages: e0166285-e0166285
- DOI
  10.1371/journal.pone.0166285
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293190, KAKENHI-PROJECT-15K06836
[Journal Article] ANGPTL2 activity in cardiac pathologies accelerates heart failure by perturbing cardiac function and energy metabolism.2016
- Author(s)
  Tian Z, Miyata K, Kadomatsu T, Horiguchi H, Fukushima H, Tohyama S, Ujihara Y, Okumura T, Yamaguchi S, Zhao J, Endo M, Morinaga J, Sato M, Sugizaki T, Zhu S, Terada K, Sakaguchi H, Komohara Y, Takeya M, Takeda N, Araki K, Manabe I, Fukuda K, Otsu K, Wada J, Murohara T, Mohri S, Yamashita JK, Sano M, Oike Y.
- Journal Title
  
  Nature Communications
  
  Volume: 7 Issue: 1 Pages: 13016-13016
- DOI
  10.1038/ncomms13016
- NAID
  120006345014
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01520, KAKENHI-PROJECT-15H06508, KAKENHI-PROJECT-26282127, KAKENHI-PROJECT-26293190, KAKENHI-PROJECT-26293218, KAKENHI-PROJECT-16K09504, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-15K06836, KAKENHI-PROJECT-16K15445
[Journal Article] Upregulation of ANGPTL6 in mouse keratinocytes enhances susceptibility to psoriasis.2016
- Author(s)
  Tanigawa H, Miyata K, Tian Z, Aoi J, Kadomatsu T, Fukushima S, Ogata A, Takeda N, Zhao J, Zhu S, Terada K, Endo M, Morinaga J, Sugizaki T, Sato M, Morioka MS, Manabe I, Mashimo Y, Hata A, Taketomi Y, Yamamoto K, Murakami M, Araki K, Jinnin M, Ihn H, Oike Y
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 34690-34690
- DOI
  10.1038/srep34690
- NAID
  120006534970
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01159, KAKENHI-ORGANIZER-24111001, KAKENHI-PROJECT-15K09772, KAKENHI-PROJECT-16K07093, KAKENHI-PROJECT-16K15122, KAKENHI-PROJECT-16K19729
[Journal Article] ANGPTL2 increases bone metastasis of breast cancer cells through enhancing CXCR4 signaling.2015
- Author(s)
  Masuda T, Endo M, Yamamoto Y, Odagiri H, Kadomatsu T, Nakamura T, Tanoue H, Ito H, Yugami M, Miyata K, Morinaga J, Horiguchi H, Motokawa I, Terada K, Morioka MS, Manabe I, Iwase H, Mizuta H, Oike Y.
- Journal Title
  
  Sci Rep.
  
  Volume: 5 Issue: 1 Pages: 9170-9170
- DOI
  10.1038/srep09170
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461114, KAKENHI-PROJECT-25461192, KAKENHI-PROJECT-25870543, KAKENHI-PUBLICLY-26116722, KAKENHI-PROJECT-26293190, KAKENHI-PROJECT-26670405
[Journal Article] The role of ANGPTL2-induced chronic inflammation in lifestyle diseases and cancer2015
- Author(s)
  Yuichi Oike, Tsuyoshi Kadomatsu, Motoyoshi Endo
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: 35 Issue: 4 Pages: 193-202
- DOI
  10.2492/inflammregen.35.193
- NAID
  130005103502
- ISSN
  1880-8190, 1880-9693
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K06836, KAKENHI-PUBLICLY-15H01159
[Journal Article] The secreted protein ANGPTL2 promotes metastasis of osteosarcoma cells through integrin alpha5beta1, p38 MAPK, and matrix metalloproteinases.2014
- Author(s)
  Odagiri et al.
- Journal Title
  
  Science Signaling
  
  Volume: 7 Issue: 309
- DOI
  10.1126/scisignal.2004612
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22113009, KAKENHI-PROJECT-24370084, KAKENHI-PROJECT-25293050, KAKENHI-PROJECT-25461114, KAKENHI-PROJECT-25461192, KAKENHI-PROJECT-25870543, KAKENHI-PROJECT-25870554, KAKENHI-PROJECT-26670107
[Journal Article] SIRT7 controls hepatic lipid metabolism by regulating the ubiquitin-proteasome pathway.2014
- Author(s)
  Yoshizawa T, Karim Md. F, Sato Y, Senokuchi T, Miyata K, Fukuda T, Go C, Tasaki M, Uchimura K, Kadomatsu T, Tian Z, Smolka C, Sawa T, Kakeya M, Tomizawa K, Ando Y, Araki E, Akaike T, Braun T, Oike Y, Bober E, Yamagata K.
- Journal Title
  
  Cell Metab.
  
  Volume: 9 Issue: 4 Pages: 712-721
- DOI
  10.1016/j.cmet.2014.03.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-11F01105, KAKENHI-ORGANIZER-20117001, KAKENHI-PLANNED-20117005, KAKENHI-PROJECT-21220010, KAKENHI-PROJECT-24390082, KAKENHI-PROJECT-24790557, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-25253020, KAKENHI-PROJECT-25293212, KAKENHI-PROJECT-25461114, KAKENHI-PROJECT-25461361, KAKENHI-PROJECT-25870543, KAKENHI-PLANNED-26111008, KAKENHI-PUBLICLY-26116722, KAKENHI-PROJECT-26293190, KAKENHI-PROJECT-26670207, KAKENHI-PROJECT-26670405, KAKENHI-PROJECT-26860697, KAKENHI-PROJECT-26861112
[Journal Article] Diverse roles of ANGPTL2 in physiology and pathophysiology.2014
- Author(s)
  Kadomatsu T, Endo M, Miyata K, Oike Y.
- Journal Title
  
  Trends Endocrinol Metab.
  
  Volume: 25(5) Issue: 5 Pages: 245-54
- DOI
  10.1016/j.tem.2014.03.012
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461114, KAKENHI-PROJECT-25461192, KAKENHI-PROJECT-25870543, KAKENHI-PUBLICLY-26116722, KAKENHI-PROJECT-26293190, KAKENHI-PROJECT-26670405
[Journal Article] Angiopoietin-like protein 2 renders colorectal cancer cells resistant to chemotherapy by activating spleen tyrosine kinase-phosphoinositide 3-kinase-dependent anti-apoptotic signaling.2014
- Author(s)
  Horiguchi H, Endo M, Miyamoto Y, Sakamoto Y, Odagiri H, Masuda T, Kadomatsu T, Tanoue H, Motokawa I, Terada K, Morioka MS, Manabe I, Baba H, Oike Y.
- Journal Title
  
  Cancer Science
  
  Volume: 105 Issue: 12 Pages: 1550-1559
- DOI
  10.1111/cas.12554
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461192, KAKENHI-PROJECT-25870543, KAKENHI-PUBLICLY-26116722, KAKENHI-PROJECT-26293190, KAKENHI-PROJECT-26462020, KAKENHI-PROJECT-26670405, KAKENHI-PROJECT-26861050
[Journal Article] Role of endothelial cell-derived angptl2 in vascular inflammation leading to endothelial dysfunction and atherosclerosis progression.2014
- Author(s)
  Horio E, Kadomatsu T, Miyata K, Arai Y, Hosokawa K, Doi Y, et al.
- Journal Title
  
  Arterioscler Thromb Vasc Biol.
  
  Volume: 34 Issue: 4 Pages: 790-800
- DOI
  10.1161/atvbaha.113.303116
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23617024, KAKENHI-PROJECT-24590797, KAKENHI-PROJECT-24590898, KAKENHI-PROJECT-24689041, KAKENHI-PROJECT-25461114, KAKENHI-PROJECT-25461192, KAKENHI-PROJECT-25670453, KAKENHI-PROJECT-25870543, KAKENHI-PROJECT-25870553, KAKENHI-PUBLICLY-26116722, KAKENHI-PROJECT-26290035, KAKENHI-PROJECT-26293190, KAKENHI-PROJECT-26640069, KAKENHI-PROJECT-26670405
[Journal Article] Tumor cell-derived angiopoietin-like protein ANGPTL2 is a critical driver of metastasis2012
- Author(s)
  Endo, M., Nakano, M., Kadomatsu, T., Fukuhara, S., Kuroda, H., Mikami, S., Hato, T., Aoi, J., Horiguchi, H., Miyata, K., Odagiri, H., Masuda, T., Harada, M., Horio, H., Hishima, T., Nomori, H., Ito, T., Yamamoto, Y., Minami, T., Okada, S., Takahashi, T.
- Journal Title
  
  Cancer Res
  
  Volume: 72 Pages: 1784-1794
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790322
[Journal Article] The role of angiopoietin-like protein 2 in pathogenesis of dermatomyositis2012
- Author(s)
  Ogata, A., Endo, M., Aoi, J., Takahashi, O., Kadomatsu, T., Miyata, K., Tian, Z., Jinnin, M., Fukushima, S., Ihn, H., & Oike, Y.
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: 418 Pages: 494-499
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790322
[Journal Article] Obesity resistance and increased hepatic expression of catabolism-related mRNAs in Cnot3(+/-) mice2011
- Author(s)
  Morita, M., Oike, Y., Nagashima, T., Kadomatsu, T., Tabata, M., Suzuki, T., Nakamura, T., Yoshida, N., Okada, M. & Yamamoto, T.
- Journal Title
  
  EMBO J
  
  Volume: 30 Pages: 4678-4691
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790322
[Journal Article] The roles of angiopoietin-like protein 2 in carcinogenesis and tumor cell metastasis2011
- Author(s)
  Aoi, J., Endo, M., Kadomatsu, T., Miyata, K., Nakano, M., Horiguchi, H., Ogata, A., Odagiri, H., Yano, M., Araki, K., Jinnin, M., Ito, T., Hirakawa, S., Ihn, H. & Oike, Y.
- Journal Title
  
  Cancer Res
  
  Volume: 71 Pages: 7502-7512
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790322
[Journal Article] Angiopoietin-like proteins : emerging targets for treatment of obesity and related metabolic diseases2011
- Author(s)
  Kadomatsu, T., Tabata, M. & Oike, Y.
- Journal Title
  
  FEBS J
  
  Volume: 278 Pages: 559-564
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790322
[Journal Article] Mitochondrial dysfunction and increased reactive oxygen species impair insulin secretion in sphingomyelin synthase 1-null mice2011
- Author(s)
  Yano, M., Watanabe, K., Yamamoto, T., Ikeda, K., Senokuchi, T., Lu, M., Kadomatsu, T., Tsukano, H., Ikawa, M., Okabe, M., Yamaoka, S., Okazaki, T., Umehara, H., Gotoh, T., Song, WJ, Node, K., Taguchi, R., Yamagata, K. & Oike, Y.
- Journal Title
  
  J. Biol. Chem
  
  Volume: 286 Pages: 3992-4002
- NAID
  120006957387
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790322
[Journal Article] Angiopoietin-like proteins : emerging targets for treatment of obesity and related metabolic diseases2011
- Author(s)
  Tsuyoshi Kadomatsu
- Journal Title
  
  FEBS Journal
  
  Volume: 278 Pages: 559-564
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790322
[Journal Article] The endoplasmic reticulum stress-C/EBP homologous protein pathway-mediated apoptosis in macrophages contributes to the instability of atherosclerotic plaques2010
- Author(s)
  Tsukano, H., Gotoh, T., Endo, M., Miyata, K., Tazume, H., Kadomatsu, T., Yano, M., Iwawaki, T., Kohno, K., Araki, K., Mizuta, H. & Oike, Y.
- Journal Title
  
  Arterioscler. Thromb. Vasc. Biol
  
  Volume: 30 Pages: 1925-1932
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790322
[Journal Article] Synoviocyte-derived angiopoietin-like protein 2 contributes to synovial chronic inflammation in rheumatoid arthritis2010
- Author(s)
  Okada, T., Tsukano, H., Endo, M., Tabata, M., Miyata, K., Kadomatsu, T., Miyashita, K., Semba, K., Nakamura, E., Tsukano, M., Mizuta, H. & Oike, Y.
- Journal Title
  
  Am. J. Pathol
  
  Volume: 176 Pages: 2309-2319
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790322
[Presentation] ANGPTL2によるエピゲノム制御を介したがん免疫逃避機構2023
- Author(s)
  門松毅、原千瑛、尾池雄一
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K07101
[Presentation] Intercellular communication via angiopoietin-like protein 2 signaling in the regulation of anti-tumor immunity2020
- Author(s)
  Tsuyoshi Kadomatsu, Haruki Horiguchi, Yuichi Oike
- Organizer
  第43回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18K07236
[Presentation] 加齢関連疾患の発症・進展とアンジオポエチン様因子2シグナル2019
- Author(s)
  門松　毅，尾池雄一
- Organizer
  第91回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-18K07236
[Presentation] アンジオポエチン様因子2シグナルによる加齢関連疾患の発症・進展の分子機構2019
- Author(s)
  門松　毅，尾池雄一
- Organizer
  第41回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18K07236
[Presentation] 加齢関連疾患とアンジオポエチン様因子2シグナル2019
- Author(s)
  門松　毅
- Organizer
  第19回日本抗加齢医学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-18K07236
[Presentation] アンジオポエチン様因子2シグナルによる代謝制御変容と加齢関連疾患2019
- Author(s)
  門松　毅
- Organizer
  第92回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-18K07236
[Presentation] Role of angiopoietin-like protein 2 in tumor development and metastasis2017
- Author(s)
  Tsuyoshi Kadomatsu
- Organizer
  「新規バイオ医薬ピロール・イミダゾール（PI）ポリアミドの創薬開発国際シンポジウム」平成28年度　日本大学学部連携研究推進シンポジウム
- Place of Presentation
  日本大学（東京都）
- Year and Date
  2017-02-24
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01159
[Presentation] Role of angiopoietin-like protein 2 in tumor development and metastasis2017
- Author(s)
  Tsuyoshi Kadomatsu
- Organizer
  「新規バイオ医薬ピロール・イミダゾール（PI）ポリアミドの創薬開発国際シンポジウム」平成28年度　日本大学学部連携研究推進シンポジウム
- Place of Presentation
  日本大学（東京都）
- Year and Date
  2017-02-24
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06836
[Presentation] がん微小環境変化による組織恒常性維持機構の活性化とがん病態進展の分子機構2016
- Author(s)
  門松　毅
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2016-12-02
- Data Source
  KAKENHI-PUBLICLY-15H01159
[Presentation] がん微小環境変化による組織恒常性維持機構の活性化とがん病態進展の分子機構2016
- Author(s)
  門松　毅
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2016-12-02
- Data Source
  KAKENHI-PROJECT-15K06836
[Presentation] 生活習慣病・がんの共通分子機構とSASPとしてのアンジオポエチン様因子2シグナル2015
- Author(s)
  門松　毅、尾池雄一
- Organizer
  BMB 2015 （第38回日本分子生物学会年会　第88回日本生化学会大会合同大会）
- Place of Presentation
  神戸ポートピアホテル（神戸市）
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PUBLICLY-15H01159
[Presentation] 生活習慣病・がんの共通分子機構とSASPとしてのアンジオポエチン様因子2シグナル2015
- Author(s)
  門松　毅、尾池雄一
- Organizer
  BMB 2015 （第38回日本分子生物学会年会　第88回日本生化学会大会合同大会）
- Place of Presentation
  神戸ポートピアホテル（神戸市）
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PROJECT-15K06836
[Presentation] 生活習慣病・がんの共通分子機構とアンジオポエチン様因子2シグナル2014
- Author(s)
  門松毅、小田切陽樹、遠藤元誉、尾池雄一
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-10-18
- Data Source
  KAKENHI-PROJECT-25870543
[Presentation] Circadian regulation of Angiopoietin-like protein 2 expression by a molecular clock2011
- Author(s)
  門松毅, 他
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-22790322
[Presentation] Clock genes directly regulate the rhythmic Angptl2 expression.2010
- Author(s)
  門松毅, 他
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸国際展示場(神戸ポートアイランド・兵庫県)
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-22790322
[Presentation] Clock genes directly regulate the rhythmic Angptl2 expression2010
- Author(s)
  門松毅
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸国際展示場(神戸ポートアイランド・兵庫県)
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-22790322
[Presentation] The Tumor Microenvironment Accelerates Tumor Cell Invasivity and Metastasis through Epigenetic Regulation of ANGPTL2
- Author(s)
  門松毅、小田切陽樹、遠藤元誉、舛田哲朗、森岡勝樹、宮田敬士、青井淳、堀口晴紀、西村尚剛、寺田和豊、薬師寺俊剛、真鍋一郎、水田博志、尾池雄一
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-25870543
[Presentation] がん微小環境はエピジェネティックなANGPTL2の発現誘導を介してがんの浸潤・転移を促進する
- Author(s)
  門松毅、小田切陽樹、遠藤元誉、舛田哲朗、森岡勝樹、福原茂朋、宮本健史、小林英介、宮田敬士、青井淳、堀口晴紀、西村尚剛、寺田和豊、薬師寺俊剛、真鍋一郎、望月直樹、水田博志、尾池雄一
- Organizer
  第10回宮崎サイエンスキャンプ
- Place of Presentation
  シーガイアコンベンションセンター
- Data Source
  KAKENHI-PROJECT-25870543

1. Yamagata Kazuya (70324770)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. Yoshizawa Tatsuya (40313530)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. Sato Yoshifumi (90622598)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. ENDO Motoyoshi (40398243)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
5. BABA Masaya (10347304)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. UEDA Mitsuharu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. ARAI Yasumichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 宮田敬士

# of Collaborated Projects: 0 results

# of Collaborated Products: 7 results
9. 安東由喜雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 向山政志

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
11. 尾池雄一

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
12. 木村俊寛

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 杉山弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KADOMATSU TSUYOSHI 門松 毅

KADOMATSU Tsuyoshi 門松 毅

Research Projects

Research Products

Co-Researchers

ウイルス性肝炎増悪-肝細胞がん発症の新規分子機構解明に基づく予防・治療戦略の創出Principal Investigator

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Basic research for developing the therapeutic strategies for rare kidney cancer based on elucidation of novel mechanisms of tumor immune evasionPrincipal Investigator

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Basic research for the development of personalized therapeutic strategies against a rare renal cell carcinomaPrincipal Investigator

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Elucidation of molecular mechanisms underlying development and progression of rare cancers caused by alteration of transcriptional regulationPrincipal Investigator

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加齢に伴う二次リンパ組織内細胞間相互作用の変容による疾患発症の分子機構解明Principal Investigator

Principal Investigator

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Molecular mechanism of diabetes mellitus based on beta-cell transcription factor network

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Epigenetic regulation of ANGPTL2 expression in cancer and lifestyle diseasePrincipal Investigator

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Analyses of the transcriptional regulatory mechanisms of chronic inflammation-related factor Angptl2Principal Investigator

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[Book] 実験医学増刊 ミトコンドリア 疾患治療の新時代 ミトコンドリア機能恒常性維持の変容と加齢関連疾患2023

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[Book] 実験医学別冊 論文図法を読む作法 細胞外フラックス解析2022

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[Book] Precision Medicine アンチエイジング科学と未来医療 心不全とRNA創薬2022

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[Book] Geriatric Medicine、 エネルギー代謝の変容・破綻と加齢疾患2021

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[Book] 別冊Bio Clinica 慢性炎症と疾患、老化と慢性炎症、老化における慢性炎症とサルコペニア2021

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[Book] 日本抗加齢医学会雑誌 アンチ・エイジング医学、 抗慢性炎症とミトコンドリア恒常性による健康長寿戦略2021

Author(s)

KADOMATSU TSUYOSHI 門松毅

KADOMATSU Tsuyoshi 門松毅

[Book] 実験医学増刊　ミトコンドリア疾患治療の新時代　ミトコンドリア機能恒常性維持の変容と加齢関連疾患2023

[Book] 実験医学別冊　論文図法を読む作法　細胞外フラックス解析2022

[Book] Precision Medicine　アンチエイジング科学と未来医療　心不全とRNA創薬2022

[Book] Geriatric Medicine、エネルギー代謝の変容・破綻と加齢疾患2021

[Book] 別冊Bio Clinica　慢性炎症と疾患、老化と慢性炎症、老化における慢性炎症とサルコペニア2021

[Book] 日本抗加齢医学会雑誌アンチ・エイジング医学、　抗慢性炎症とミトコンドリア恒常性による健康長寿戦略2021

[Book] アンチ・エイジング医学　特集老化と炎症　5. 慢性炎症とサルコペニア2019

[Book] 血管医学　特集：臓器の記憶と血管代謝ニッシェ2015