Hosokawa Kentaro 細川健太郎

… Alternative Names

HOSOKAWA Kentaro 細川健太郎

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Researcher Number	90569584
Other IDs
Affiliation (Current)	2025: 九州大学, 医学研究院, 講師
Affiliation (based on the past Project Information) *help	2017 – 2024: 九州大学, 医学研究院, 講師 2016 – 2017: 九州大学, 医学研究院, 助教 2014 – 2015: 九州大学, 医学(系)研究科(研究院), 助教 2014: 九州大学, 応用幹細胞医科学部門・幹細胞再生修復医学分野, 助教 2011 – 2013: 慶應義塾大学, 医学部, 特任助教 2012: 慶應義塾大学, 医学部, 講師 2010: 慶應義塾大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Hematology / Basic Section 54010:Hematology and medical oncology-related Except Principal Investigator Hematology / Basic Section 54010:Hematology and medical oncology-related
Keywords	Principal Investigator 造血幹細胞 / ニッチ / 間葉系幹細胞 / Foxp2 / 老化 / テロメア / 自己複製 / 発生・分化 / 体外増幅 / 急性骨髄性白血病 … More / 造血支持 / DNA損傷 / 分化制御 / 転写因子 / 静止期 / 細胞周期 / シングルセル / 骨内膜 / 骨芽細胞 / 細胞老化 / DNA損傷応答 / 骨髄移植 / 細胞増殖 / 細胞分裂 / Hippo / Flower / 増殖制御 / 細胞競合 / 蛋白質 / 再生医学 / 細胞・組織 / 移植・再生医療 / 遺伝子 / single cell / Angiopoietin-1 / Paired daughter cells / Tie2 / 単一細胞 / 非対称分裂 … More Except Principal Investigator ニッチ / 造血幹細胞 / 間葉系幹細胞 / 幹細胞ニッチ / ニッチ分子 / Itga8 / 骨内膜 / Pot1a / シェルタリン / 造血幹細胞ニッチ / POT1a / シェルタリン因子 / POT1 / 再生医学 / 対称・非対称分裂 / 自己複製分裂 / 機械学習モデル / 人工ニューラルネットワーク / 人工ニッチ / 非対称分裂 / イギリス・スイス / 国際情報交換 / 造血幹細胞分裂 / 幹細胞維持 / 単一細胞 / 娘幹細胞 / ニッチ因子 / プロスタグランディン / 炎症 / 低酸素 / 活性酸素 / 白血病幹細胞 Less

Elucidation of the mechanism of hematopoietic stem cell maintenance by newly identified bone marrow mesenchymal stem cells.
- Principal Investigator
  
  新井文用
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kyushu University
Function of telomere binding factors in normal and tumor hematopoietic microenvironmentsPrincipal Investigator
- Principal Investigator
  
  細川健太郎
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kyushu University
Identification of transcriptional signaling networks that control the quality and quantity of the bone marrow microenvironmentPrincipal Investigator
- Principal Investigator
  
  Hosokawa Kentaro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kyushu University
Elucidating the functional regulation mechanism of the hematopoietic microenvironment (niche) by the shelterin factor
- Principal Investigator
  
  Arai Fumio
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kyushu University
Function of Foxp2 in the maintenance of hematopoietic stem cells.Principal Investigator
- Principal Investigator
  
  Hosokawa Kentaro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kyushu University
Elucidation of the mechanism of asymmetric division of hematopoietic stem cells using the next-generation artificial niche
- Principal Investigator
  
  Arai Fumio
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Kyushu University
Identification of novel MSCs with hematopoiesis supporting capacityPrincipal Investigator
- Principal Investigator
  
  Hosokawa Kentaro
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  Kyushu University
Challenge to the ex vivo expansion technology of human hematopoietic stem cells by exogenous telomere-binding protein POT1Principal Investigator
- Principal Investigator
  
  HOSOKAWA Kentaro
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  Kyushu University
  Keio University
Analyses of hematopoietic stem cell division patterns in biomimetic culture conditions and optimization of culture condition for hematopoietic stem cells
- Principal Investigator
  
  IKUSHIMA Yoshiko
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Hematology
- Research Institution
  Research Institute, International Medical Center of Japan
  Keio University
Function of Flower system in the regulation of hematopoietic stem cellPrincipal Investigator
- Principal Investigator
  
  HOSOKAWA Kentaro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Hematology
- Research Institution
  Kyushu University
  Keio University
Nicher Regulation for Normal Hemopoietic Stem Cells and Leukemic Stem Cells
- Principal Investigator
  
  SUDA Toshio
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Hematology
- Research Institution
  Keio University
Single cell Analysis of asymmetrical cell division of hematopoietic stem cellPrincipal Investigator
- Principal Investigator
  
  HOSOKAWA Kentaro
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hematology
- Research Institution
  Keio University

All 2023 2022 2020 2018 2017 2014 2013 2012 2011 2010 Other

All Journal Article Presentation

[Journal Article] POT1a deficiency in mesenchymal niches perturbs B-lymphopoiesis2023
- Author(s)
  Nakashima Kentaro、Kunisaki Yuya、Hosokawa Kentaro、Gotoh Kazuhito、Yao Hisayuki、Yuta Ryosuke、Semba Yuichiro、Nogami Jumpei、Kikushige Yoshikane、Stumpf Patrick S.、MacArthur Ben D.、Kang Dongchon、Akashi Koichi、Ohga Shouichi、Arai Fumio
- Journal Title
  
  Communications Biology
  
  Volume: 6 Issue: 1 Pages: 1-14
- DOI
  10.1038/s42003-023-05374-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K18301, KAKENHI-PROJECT-23K07861, KAKENHI-PROJECT-21H04827, KAKENHI-PROJECT-21H02950, KAKENHI-PROJECT-23K24364, KAKENHI-PROJECT-23K27626
[Journal Article] Machine Learning of Hematopoietic Stem Cell Divisions from Paired Daughter Cell Expression Profiles Reveals Effects of Aging on Self-Renewal2020
- Author(s)
  Arai Fumio、Stumpf Patrick S.、Ikushima Yoshiko M.、Hosokawa Kentaro、Roch Aline、Lutolf Matthias P.、Suda Toshio、MacArthur Ben D.
- Journal Title
  
  Cell Systems
  
  Volume: 11 Issue: 6 Pages: 640-652
- DOI
  10.1016/j.cels.2020.11.004
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08733, KAKENHI-PROJECT-19K16547, KAKENHI-PROJECT-18H05284, KAKENHI-PROJECT-20H03711, KAKENHI-PROJECT-19K22638
[Journal Article] Mitochondrial Protein Synthesis Is Essential for Terminal Differentiation of CD45? TER119?Erythroid and Lymphoid Progenitors2020
- Author(s)
  Gotoh Kazuhito、Kunisaki Yuya、Mizuguchi Soichi、Setoyama Daiki、Hosokawa Kentaro、Yao Hisayuki、Nakashima Yuya、Yagi Mikako、Uchiumi Takeshi、Semba Yuichiro、Nogami Jumpei、Akashi Koichi、Arai Fumio、Kang Dongchon
- Journal Title
  
  iScience
  
  Volume: 23 Issue: 11 Pages: 101654-101654
- DOI
  10.1016/j.isci.2020.101654
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08733, KAKENHI-PROJECT-20H00530, KAKENHI-PROJECT-18H02841, KAKENHI-PROJECT-20H03711, KAKENHI-PROJECT-18K11077, KAKENHI-PROJECT-19K22638
[Journal Article] The role of telomere binding molecules for normal and abnormal hematopoiesis.2018
- Author(s)
  Hosokawa K, Arai F.
- Journal Title
  
  Int J Hematol.
  
  Volume: 印刷中 Issue: 6 Pages: 646-655
- DOI
  10.1007/s12185-018-2432-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09907, KAKENHI-PROJECT-17H04208
[Journal Article] The telomere binding protein Pot1 maintains haematopoietic stem cell activity with age2017
- Author(s)
  Hosokawa Kentaro、MacArthur Ben D.、Ikushima Yoshiko Matsumoto、Toyama Hirofumi、Masuhiro Yoshikazu、Hanazawa Shigemasa、Suda Toshio、Arai Fumio
- Journal Title
  
  Nature Communications
  
  Volume: 8(804) Issue: 1 Pages: 804-818
- DOI
  10.1038/s41467-017-00935-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09907, KAKENHI-PROJECT-16K19067, KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-17H04208
[Journal Article] Functional analysis of Protection of Telomeres 1a (Pot1a) in regulation of hematopoietic stem cell aging2017
- Author(s)
  Hosokawa K, Macarthur BD, Ikushima Y, Toyama H, Masuhiro Y, Hanazawa S, Suda T, Arai F.
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 58 Issue: 8 Pages: 942-949
- DOI
  10.11406/rinketsu.58.942
- NAID
  130006067976
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09907, KAKENHI-PROJECT-26221309
[Journal Article] Role of endothelial cell-derived angptl2 in vascular inflammation leading to endothelial dysfunction and atherosclerosis progression.2014
- Author(s)
  Horio E, Kadomatsu T, Miyata K, Arai Y, Hosokawa K, Doi Y, et al.
- Journal Title
  
  Arterioscler Thromb Vasc Biol.
  
  Volume: 34 Issue: 4 Pages: 790-800
- DOI
  10.1161/atvbaha.113.303116
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23617024, KAKENHI-PROJECT-24590797, KAKENHI-PROJECT-24590898, KAKENHI-PROJECT-24689041, KAKENHI-PROJECT-25461114, KAKENHI-PROJECT-25461192, KAKENHI-PROJECT-25670453, KAKENHI-PROJECT-25870543, KAKENHI-PROJECT-25870553, KAKENHI-PUBLICLY-26116722, KAKENHI-PROJECT-26290035, KAKENHI-PROJECT-26293190, KAKENHI-PROJECT-26640069, KAKENHI-PROJECT-26670405
[Journal Article] Determining C-Myb protein levels can isolate functional hematopoietic stem cell subtypes.2014
- Author(s)
  Sakamoto H, Takeda N, Arai F, Hosokawa K, Garcia P, Suda T, Frampton J, Ogawa M
- Journal Title
  
  Stem Cells
  
  Volume: 33 Issue: 2 Pages: 479-490
- DOI
  10.1002/stem.1855
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22130004, KAKENHI-PROJECT-24591400, KAKENHI-PROJECT-24689041, KAKENHI-PROJECT-25670453, KAKENHI-PROJECT-26293228, KAKENHI-PROJECT-26670471, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-26221309
[Journal Article] Enhanced Angptl/Tie2 signaling affects the differentiation and long-term repopulation ability of hematopoietic stem cells.2013
- Author(s)
  Ikushima YM. Arai F, Nakamura Y, Hosokawa K, Kubota Y, Hirashima M, Toyama H, Suda T
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 130(1) Issue: 1 Pages: 20-25
- DOI
  10.1016/j.bbrc.2012.11.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J04866, KAKENHI-PLANNED-22122002, KAKENHI-PLANNED-22130004, KAKENHI-PROJECT-23249053, KAKENHI-PROJECT-24689041
[Journal Article] Nucleostemin is indispensable for the maintenance and genetic stability of hematopoietic stem cells.2013
- Author(s)
  Yamashita M, Nitta E, Nagamatsu G, Ikushima YM, Hosokawa K, Arai F, Suda T
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 441 Issue: 1 Pages: 196-201
- DOI
  10.1016/j.bbrc.2013.10.032
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J40105, KAKENHI-PROJECT-13J05828, KAKENHI-PLANNED-22130004, KAKENHI-PROJECT-23249053, KAKENHI-PROJECT-23618011, KAKENHI-PUBLICLY-24116522, KAKENHI-PROJECT-24689041, KAKENHI-PROJECT-25670453, KAKENHI-PROJECT-25893234
[Journal Article] p57(Kip2) and p27(Kip1) cooperate to maintain hematopoietic stem cell quiescence through interactions with Hsc702011
- Author(s)
  Zou P, Yoshihara H, Hosokawa K, Tai I, Shinmyozu K, Tsukahara F, Maru Y, Nakayama K, Nakayama KI, Suda T
- Journal Title
  
  Cell Stem Cell
  
  Volume: 9(3) Pages: 247-261
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790920
[Journal Article] Telomerase reverse transcriptase protects ATM-deficient hematopoietic stem cells from ROS-induced apoptosis through a telomere-independent mechanism2011
- Author(s)
  Nitta E, Yamashita M, Hosokawa K, Xian M, Takubo K, Arai F, Nakada S, Suda T
- Journal Title
  
  Blood
  
  Volume: 117(16) Pages: 4169-4180
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790920
[Journal Article] Knockdown of N-cadherin suppresses the long-term engraftment of hematopoietic stem cells.2011
- Author(s)
  Hosokawa K., et al.
- Journal Title
  
  Blood
  
  Volume: 116 Pages: 554-563
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790920
[Journal Article] Cadherin-based adhesion is a potential target for niche manipulation to protect hematopoietic stem cells in adult bone marrow2010
- Author(s)
  Hosokawa K, Arai F, Yoshihara H, Iwasaki H, Hembree M, Yin T, Nakamura Y, Gomei Y, Takubo K, Shiama H, Matsuoka S, Li L, Suda T
- Journal Title
  
  Cell Stem Cell
  
  Volume: 6(3) Pages: 194-198
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790920
[Journal Article] Functional differences between two Tie2 ligands, angiopoietin-1 and-2, in regulation of adult bone marrow hematopoietic stem cells2010
- Author(s)
  Gomei Y, Nakamura Y, Yoshihara H, Hosokawa K, Iwasaki H, Suda T, Arai F
- Journal Title
  
  Exp Hematol
  
  Volume: 38 Pages: 82-89
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790920
[Journal Article] Isolation and characterization of endosteal niche cell populations that regulate hematopoietic stem cells2010
- Author(s)
  Nakamura Y, Arai F, Iwasaki H, Hosokawa K, Kobayashi I, Gomei Y, Matsumoto Y, Yoshihara H, Suda T
- Journal Title
  
  Blood
  
  Volume: 116(9) Pages: 1422-1432
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790920
[Journal Article] Knockdown of N-cadherin suppresses the long-term engraftment of hematopoietic stem cells2010
- Author(s)
  Hosokawa K, Arai F, Yoshihara H, Iwasaki H, Nakamura Y, Gomei Y, Suda T
- Journal Title
  
  Blood
  
  Volume: 116(4) Pages: 554-563
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790920
[Presentation] POT1a is essential for mesenchymal niches supporting B cell development2022
- Author(s)
  Nakashima K, Kunisaki Y, Hosokawa K, Yao H, Yuta R, Akashi K, Ohga S, Arai F
- Organizer
  第84回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03711
[Presentation] Identification and characterization of integrin α8-positive MSCs located in the endosteal niche2022
- Author(s)
  Yuta R, Yao H, Hosokawa K, Kunisaki Y, Semba Y, Arai F
- Organizer
  第84回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03711
[Presentation] POT1a deficiency in mesenchymal niche cells results in bone marrow failures and skeletal retardation2018
- Author(s)
  Kentaro Nakashima, Yuya Kunisaki, Kentaro Hosokawa, Shouichi Ohga, Fumio Arai
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09907
[Presentation] 造血幹細胞の未分化性維持における転写因子Foxp2の機能解析2017
- Author(s)
  Saki Morimoto, Kentaro Hosokawa, Yuya Kunisaki, Haruka Imanishi, Tomoko Hyoda, Yasufumi Uehara, Fumio Arai
- Organizer
  第79回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09907
[Presentation] Foxp2 is necessary for maintenance of quiescence in hematopoietic stem cells.2017
- Author(s)
  Kentaro Hosokawa, Saki Morimoto, Yuya Kunisaki, Haruka Imanishi, Tomoko Hyoda, Yasufumi Uehara, and Fumio Arai
- Organizer
  ISEH 46th Annual Scientific Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09907
[Presentation] 単一細胞レベルでの娘細胞解析に基づくAngpt1の造血幹細胞分裂パターン決定における作用について2014
- Author(s)
  生島芳子, Ben D MacArthur, Patrick S Stumph, 細川健太郎, Alain Roch, Matthias P Lutolf, 須田年生, 新井文用
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-10-31
- Data Source
  KAKENHI-PROJECT-25893234
[Presentation] Functional analysis of POT1 in the maintenance of Hematopoietic stem cells.2013
- Author(s)
  Kentaro Hosokawa, Fumio Arai, Yumiko Gomei and Toshio Suda
- Organizer
  第11回幹細胞シンポジウム
- Place of Presentation
  東京大学、　東京
- Data Source
  KAKENHI-PROJECT-25670453
[Presentation] Shelterin component protection of telomeres 1 (Pot1) plays a critical role in the self-renewal of HSCs.2013
- Author(s)
  Kentaro Hosokawa, Toshio Suda and Fumio Arai.
- Organizer
  ISEH 42th Annual Scientific Meeting
- Place of Presentation
  The Imperial Riding School Renaissance Hotel Vienna, Austria
- Data Source
  KAKENHI-PROJECT-24689041
[Presentation] Shelterin component protection of telomeres 1 (Pot1) plays a critical role in the self-renewal of HSCs.2013
- Author(s)
  Kentaro Hosokawa, Toshio Suda and Fumio Arai.
- Organizer
  ISEH 42th Annual Scientific Meeting
- Place of Presentation
  The Imperial Riding School Renaissance Hotel Vienna, Austria
- Data Source
  KAKENHI-PROJECT-25670453
[Presentation] Shelterin component protection of telomeres 1 (Pot1) plays a critical role in the self-renewal of HSCs.2013
- Author(s)
  Kentaro Hosokawa, Toshio Suda and Fumio Arai.
- Organizer
  第75回日本血液学会学術集会
- Place of Presentation
  ロイトン札幌、　北海道（札幌）
- Data Source
  KAKENHI-PROJECT-25670453
[Presentation] Functional analysis of POT1 in the maintenance of Hematopoietic stem cells.2013
- Author(s)
  Kentaro Hosokawa, Fumio Arai, Yumiko Gomei and Toshio Suda.
- Organizer
  第11回幹細胞シンポジウム
- Place of Presentation
  東京大学　東京都（東京）
- Data Source
  KAKENHI-PROJECT-24689041
[Presentation] Shelterin component protection of telomeres 1 (Pot1) plays a critical role in the self-renewal of HSCs.2013
- Author(s)
  Kentaro Hosokawa, Toshio Suda and Fumio Arai.
- Organizer
  第75回日本血液学会学術集会
- Place of Presentation
  ロイトン札幌北海道（札幌）
- Data Source
  KAKENHI-PROJECT-24689041
[Presentation] FUNCTIONAL ANALYSIS OF POTl IN THE MAINTENANCE OF HEMATOPOIETIC STEM CELLS.2012
- Author(s)
  Kentaro Hosokawa
- Organizer
  IS EH 41th Annual Scientific Meeting
- Place of Presentation
  Amsterdam, Netherlands
- Year and Date
  2012-08-25
- Data Source
  KAKENHI-PROJECT-24689041
[Presentation] Function of Protection of Telomere (POT1) in the maintenance of hematopoietic stem cells2011
- Author(s)
  細川健太郎
- Organizer
  KEY Forum in Developmental Biology and Regenerative Medicine
- Place of Presentation
  熊本大学・熊本
- Year and Date
  2011-09-09
- Data Source
  KAKENHI-PROJECT-22790920
[Presentation] Function of Protection of Telomere(POT1) in the maintenance of hematopoietic stem cells2011
- Author(s)
  Hosokawa K, Arai F, Nojima Y and Suda T
- Organizer
  KEY Forum in Developmental Biology and Regenerative Medicine
- Place of Presentation
  Kumamoto(Japan)
- Data Source
  KAKENHI-PROJECT-22790920
[Presentation] FUNCTION OF PROTECTION OF TELOMERE (POT1) IN THE MAINTENANCE OF HEMATOPOIETIC STEM CELLS.2010
- Author(s)
  細川健太郎
- Organizer
  ISEH 40th Annual Scientific Meeting
- Place of Presentation
  Melbourne, Australia
- Year and Date
  2010-08-17
- Data Source
  KAKENHI-PROJECT-22790920
[Presentation] FUNCTION OF PROTECTION OF TELOMERE(POT1) IN THE MAINTENANCE OF HEMATOPOIETIC STEM CELLS2010
- Author(s)
  Hosokawa K, Arai F, Nojima Y and Suda T
- Organizer
  ISEH 2010 Meeting
- Place of Presentation
  Melbourne(Australia)
- Data Source
  KAKENHI-PROJECT-22790920
[Presentation] Function of Protection of Telomere(Pot1) in the maintenance of hematopoietic stem cells2010
- Author(s)
  Hosokawa K, Arai F, Nojima Y and Suda T
- Organizer
  第72回日本血液学会学術集会
- Place of Presentation
  横浜(神奈川)
- Data Source
  KAKENHI-PROJECT-22790920
[Presentation] Protection of Telomere (Pot1)による造血幹細胞の静止期状態維持機構の解析2010
- Author(s)
  細川健太郎
- Organizer
  第72回日本血液学会学術集会
- Place of Presentation
  横浜市、横浜
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-22790920
[Presentation] POT1 regulates self-renewal activity of cord blood hematopoietic stem cells
- Author(s)
  Kentaro Hosokawa, Yoshiko Ikushima, Benjamin MacArthur, Toshio Suda, Fumio Arai
- Organizer
  ISEH 43rd Annual Scientific Meeting
- Place of Presentation
  Montreal, Canada
- Year and Date
  2014-08-21 – 2014-08-24
- Data Source
  KAKENHI-PROJECT-24689041
[Presentation] Single cell-based analyses of cell division pattern of hematopoietic stem cells
- Author(s)
  Ikushima YM, MacArthur BD, Hosokawa K, Lutolf MP, Suda T, Arai F
- Organizer
  75th Annual Meeting of the Japanese Society of Hematology
- Place of Presentation
  Sapporo, Japan
- Data Source
  KAKENHI-PROJECT-25893234
[Presentation] POT1 regulates self-renewal activity of cord blood hematopoietic stem cells.
- Author(s)
  Kentaro Hosokawa, Yoshiko Ikushima, Benjamin MacArthur, Toshio Suda, Fumio Arai.
- Organizer
  ISEH 43th Annual Scientific Meeting.
- Place of Presentation
  Montreal, Canada
- Year and Date
  2014-08-21 – 2014-08-24
- Data Source
  KAKENHI-PROJECT-25670453
[Presentation] Pot1 regulates hematopoietic stem cell activity during aging
- Author(s)
  Kentaro Hosokawa, Yoshiko Ikushima, Benjamin MacArthur, Toshio Suda, Fumio Arai
- Organizer
  第12回幹細胞シンポジウム
- Place of Presentation
  福岡県、福岡
- Year and Date
  2014-05-30 – 2014-05-31
- Data Source
  KAKENHI-PROJECT-25670453
[Presentation] Pot1 regulates hematopoietic stem cell activity during aging
- Author(s)
  Kentaro Hosokawa, Yoshiko Ikushima, Benjamin MacArthur, Toshio Suda, Fumio Arai
- Organizer
  第12回幹細胞シンポジウム
- Place of Presentation
  福岡県、福岡
- Year and Date
  2014-05-30 – 2014-05-31
- Data Source
  KAKENHI-PROJECT-24689041

1. ARAI Fumio (90365403)

# of Collaborated Projects: 7 results

# of Collaborated Products: 12 results
2. SUDA Toshio (60118453)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
3. 八尾尚幸 (90835282)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
4. TAKUBO Keiyo (50502788)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. NAGAMATSU Go (70453545)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. IKUSHIMA Yoshiko (00571366)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. 国崎祐哉 (80737099)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. MACARTHUR Ben D.

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. STUMPF Patrich S

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. LUTOLF Matthias P.

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. ARAI Yasumichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hosokawa Kentaro 細川 健太郎

HOSOKAWA Kentaro 細川 健太郎

Research Projects

Research Products

Co-Researchers

Elucidation of the mechanism of hematopoietic stem cell maintenance by newly identified bone marrow mesenchymal stem cells.

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Function of telomere binding factors in normal and tumor hematopoietic microenvironmentsPrincipal Investigator

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Identification of transcriptional signaling networks that control the quality and quantity of the bone marrow microenvironmentPrincipal Investigator

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Elucidating the functional regulation mechanism of the hematopoietic microenvironment (niche) by the shelterin factor

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Function of Foxp2 in the maintenance of hematopoietic stem cells.Principal Investigator

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Elucidation of the mechanism of asymmetric division of hematopoietic stem cells using the next-generation artificial niche

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Identification of novel MSCs with hematopoiesis supporting capacityPrincipal Investigator

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Challenge to the ex vivo expansion technology of human hematopoietic stem cells by exogenous telomere-binding protein POT1Principal Investigator

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Analyses of hematopoietic stem cell division patterns in biomimetic culture conditions and optimization of culture condition for hematopoietic stem cells

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Function of Flower system in the regulation of hematopoietic stem cellPrincipal Investigator

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Nicher Regulation for Normal Hemopoietic Stem Cells and Leukemic Stem Cells

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Single cell Analysis of asymmetrical cell division of hematopoietic stem cellPrincipal Investigator

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[Journal Article] POT1a deficiency in mesenchymal niches perturbs B-lymphopoiesis2023

Author(s)

Journal Title

Hosokawa Kentaro 細川健太郎

HOSOKAWA Kentaro 細川健太郎