Yamane Syunsuke 山根俊介

… Alternative Names

YAMANE Shunsuke 山根俊介

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Researcher Number	90582156
Other IDs
Affiliation (Current)	2025: 京都大学, 医学研究科, 客員研究員
Affiliation (based on the past Project Information) *help	2023 – 2024: 京都大学, 医学研究科, 客員研究員 2016 – 2022: 京都大学, 医学研究科, 助教 2016: 京都大学, 医学研究科, 特定病院助教 2014 – 2015: 京都大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field	Principal Investigator Basic Section 54040:Metabolism and endocrinology-related / Metabolomics Except Principal Investigator Basic Section 54040:Metabolism and endocrinology-related / Metabolomics
Keywords	Principal Investigator インクレチン分泌 / GLP-1 / CACNA2D1 / CAR8 / 脂質代謝異常 / Gタンパク質シグナル伝達調節因子 / 細胞内局在 / 脂肪酸結合タンパク / GIP / 肥満症 / 肥満 / インクレチン … More Except Principal Investigator … More GLP-1 / GIP / インクレチン / インクレチン分泌 / GPR120 / CCK / 腸管内分泌ホルモン / Incretin / L細胞 / K細胞 Less

GIP/GLP-1受容体共刺激による血糖降下・体重減少作用増強メカニズムの解明
- Principal Investigator
  
  稲垣暢也
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  The Tazuke Kofukai
電位依存性Ca2+チャネルα2δサブユニットを介したGLP-1分泌制御機構の解明Principal Investigator
- Principal Investigator
  
  山根俊介
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Kyoto University
Integrated analysis of enteroendocrine hormone secretion mechanisms involved in nutrient sensing
- Principal Investigator
  
  Inagaki Nobuya
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  The Tazuke Kofukai
  Kyoto University
Elucidation of the regulatory mechanism of GLP-1 secretion by carbonic anhydrase 8 (Car8)Principal Investigator
- Principal Investigator
  
  Yamane Shunsuke
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Kyoto University
Analysis of the mechanisms of incretin secretion: similarities or differences of GIP and GLP-1 secretion
- Principal Investigator
  
  Inagaki Nobuya
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  Kyoto University
Investigation of regulatory mechanisim of GIP secretion by fatty-acid binding protein 5 (FABP5)Principal Investigator
- Principal Investigator
  
  Yamane Shunsuke
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Kyoto University
Functional analysis of transcription factor Rfx6 in GIP-producing K-cellPrincipal Investigator
- Principal Investigator
  
  YAMANE Shunsuke
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  Kyoto University

All 2023 2022 2021 2019 2018 2017 2016 2015 2014 Other

All Journal Article Presentation

[Journal Article] Inhibition of GPR120 signaling in intestine ameliorates insulin resistance and fatty liver under high-fat diet feeding2023
- Author(s)
  Yasuda Takuma、Harada Norio、Hatoko Tomonobu、Ichimura Atsuhiko、Ikeguchi-Ogura Eri、Murata Yuki、Wada Naoki、Kiyobayashi Sakura、Yamane Shunsuke、Hirasawa Akira、Inagaki Nobuya
- Journal Title
  
  American Journal of Physiology-Endocrinology and Metabolism
  
  Volume: - Issue: 5 Pages: E449-E460
- DOI
  10.1152/ajpendo.00329.2022
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03731, KAKENHI-PROJECT-20H03802, KAKENHI-PROJECT-22K08668, KAKENHI-PROJECT-23K27378
[Journal Article] Carbonic anhydrase 8 (CAR8) negatively regulates GLP-1 secretion from enteroendocrine cells in response to long-chain fatty acids.2021
- Author(s)
  7.Fujiwara Y, Yamane S, Harada N, Ikeguchi-Ogura E, Usui R, Nakamura T, Iwasaki K, Suzuki K, Yabe D, Hayashi Y, Inagaki N.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol.
  
  Volume: 320
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08977
[Journal Article] Gene expression of nutrient-sensing molecules in I cells of CCK reporter male mice2021
- Author(s)
  Kato T, Harada N, Ikeguchi-Ogura E, Sankoda A, Hatoko T, Lu X, Yasuda T, Yamane S, Inagaki N.
- Journal Title
  
  J Mol Endocrinol.
  
  Volume: 66 Issue: 1 Pages: 11-22
- DOI
  10.1530/jme-20-0134
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09022, KAKENHI-PROJECT-20K21616, KAKENHI-PROJECT-20H03731
[Journal Article] Carbonic anhydrase 8 (CAR8) negatively regulates GLP-1 secretion from enteroendocrine cells in response to long-chain fatty acids2021
- Author(s)
  Fujiwara Yuta、Yamane Shunsuke、Harada Norio、Ikeguchi-Ogura Eri、Usui Ryota、Nakamura Toshihiro、Iwasaki Kanako、Suzuki Kazuyo、Yabe Daisuke、Hayashi Yoshitaka、Inagaki Nobuya
- Journal Title
  
  American Journal of Physiology-Gastrointestinal and Liver Physiology
  
  Volume: 320 Issue: 4 Pages: 1-1
- DOI
  10.1152/ajpgi.00312.2020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08977, KAKENHI-PROJECT-19K09022, KAKENHI-PROJECT-20K17489, KAKENHI-PROJECT-18H03176, KAKENHI-PROJECT-20H03731, KAKENHI-PROJECT-18K16196, KAKENHI-PROJECT-20K21616, KAKENHI-PROJECT-21K19504
[Journal Article] Medium-chain triglycerides inhibit long-chain triglyceride-induced GIP secretion through GPR120-dependent inhibition of CCK.2021
- Author(s)
  Murata Y, Harada N, Kishino S, Iwasaki K, Ikeguchi-Ogura E, Yamane S, Kato T, Kanemaru Y, Sankoda A, Hatoko T, Kiyobayashi S, Ogawa J, Hirasawa A, Inagaki N.
- Journal Title
  
  iScience.
  
  Volume: 24 Issue: 9 Pages: 102963-102963
- DOI
  10.1016/j.isci.2021.102963
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09022, KAKENHI-PROJECT-20K21616, KAKENHI-PROJECT-20H03731
[Journal Article] Medium-chain triglyceride diet stimulates less GIP secretion and suppresses body weight and fat mass gain compared with long-chain triglyceride diet.2019
- Author(s)
  Murata Y, Harada N, Yamane S, Iwasaki K, Ikeguchi E, Kanemaru Y, Harada T, Sankoda A, Shimazu-Kuwahara S, Joo E, Poudyal H, Inagaki N.
- Journal Title
  
  Am J Physiol Endocrinol Metab.
  
  Volume: accept Pages: 0-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05326
[Journal Article] Free fatty acid receptor GPR120 and GPR40 are essential for oil-induced GIP secretion.2019
- Author(s)
  Sankoda A, Harada N, Kato T, Iwasaki K, Yamane S, Ikeguchi E, Murata Y, Hirasawa A, Inagaki N.
- Journal Title
  
  J Diabetes Investig.
  
  Volume: accept Pages: 0-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05326
[Journal Article] Glucose-dependent insulinotropic polypeptide deficiency reduced fat accumulation and insulin resistance, but deteriorated bone loss in ovariectomized mice2018
- Author(s)
  Shimazu-Kuwahara Satoko、Kanemaru Yoshinori、Harada Norio、Ikeguchi Eri、Ueda Yohei、Yamane Shunsuke、Murata Yuki、Yasoda Akihiro、Kieffer Timothy J、Inagaki Nobuya
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: Epub Issue: 4 Pages: 0-0
- DOI
  10.1111/jdi.12978
- NAID
  120006708221
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16197, KAKENHI-PROJECT-16H05326, KAKENHI-PROJECT-16K09745
[Journal Article] Effects of three major amino acids found inJapanese broth on glucose metabolism and gastric emptying.2018
- Author(s)
  Mano F, Ikeda K, Joo E, Yamane S, Harada N, Inagaki N.
- Journal Title
  
  Nutrition
  
  Volume: 46 Pages: 153-158
- DOI
  10.1016/j.nut.2017.08.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05326
[Journal Article] Transcriptional factor Pdx1 is involved in age-related GIP hypersecretion in mice.2018
- Author(s)
  Ikeguchi E, Harada N, Kanemaru Y, Sankoda A, Yamane S, Iwasaki K, Imajo M, Murata Y, Suzuki K, Joo E, Inagaki N.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol.
  
  Volume: 315
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09778
[Journal Article] Transcriptional factor Pdx1 is involved in age-related GIP hypersecretion in mice.2018
- Author(s)
  Ikeguchi E, Harada N, Kanemaru Y, Sankoda A, Yamane S, Iwasaki K, Imajo M, Murata Y, Suzuki K, Joo E, Inagaki N.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol.
  
  Volume: 315 Issue: 2 Pages: 272-272
- DOI
  10.1152/ajpgi.00054.2018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05326, KAKENHI-PROJECT-16K09745, KAKENHI-PROJECT-17K19654
[Journal Article] Inhibition of Gastric Inhibitory Polypeptide Receptor Signaling in Adipose Tissue Reduces Insulin Resistance and Hepatic Steatosis in High-Fat Diet-Fed Mice.2017
- Author(s)
  Joo E, Harada N, Yamane S, Fukushima T, Taura D, Iwasaki K, Sankoda A, Shibue K, Harada T, Suzuki K, Hamasaki A, Inagaki N.
- Journal Title
  
  Diabetes.
  
  Volume: 66 Issue: 4 Pages: 868-868
- DOI
  10.2337/db16-0758
- NAID
  40021434294
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H05326, KAKENHI-PROJECT-16K19535, KAKENHI-PROJECT-16K09745, KAKENHI-PROJECT-16K09778, KAKENHI-PROJECT-15J40068, KAKENHI-PROJECT-16K16276
[Journal Article] Distribution and hormonal characterization of primary murine L cells throughout the gastrointestinal tract2017
- Author(s)
  Suzuki Kazuyo、Iwasaki Kanako、Murata Yuki、Harada Norio、Yamane Shunsuke、Hamasaki Akihiro、Shibue Kimitaka、Joo Erina、Sankoda Akiko、Fujiwara Yuta、Hayashi Yoshitaka、Inagaki Nobuya
- Journal Title
  
  J Diabetes Investig
  
  Volume: 9 Issue: 1 Pages: 25-32
- DOI
  10.1111/jdi.12681
- NAID
  120006376021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09778, KAKENHI-PROJECT-15H04681, KAKENHI-PROJECT-16H05326, KAKENHI-PROJECT-15J40068, KAKENHI-PROJECT-15K15356
[Journal Article] Long chain free fatty acid receptor GPR120 mediates oil-induced GIP secretion through CCK in male mice.2017
- Author(s)
  19.Sankoda A, Harada N, Iwasaki K, Yamane S, Murata Y, Shibue K, Thewjitcharoen Y, Suzuki K, Harada T, Kanemaru Y, Shimazu-Kuwahara S, Hirasawa A, Inagaki N.
- Journal Title
  
  Endocrinology.
  
  Volume: In press Issue: 5 Pages: 0-0
- DOI
  10.1210/en.2017-00090
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H05326, KAKENHI-PROJECT-15J40068, KAKENHI-PROJECT-16K19535, KAKENHI-PROJECT-16K09745, KAKENHI-PROJECT-16K09778
[Journal Article] Attenuated secretion of glucose-dependent insulinotropic polypeptide (GIP) does not alleviate hyperphagic obesity and insulin resistance in ob/ob mice.2017
- Author(s)
  Shimazu-Kuwahara S, Harada N, Yamane S, Joo E, Sankoda A, Kieffer TJ, Inagaki N.
- Journal Title
  
  Mol Metab.
  
  Volume: 19 Issue: 3 Pages: 288-288
- DOI
  10.1016/j.molmet.2017.01.006
- NAID
  120005997778
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H05326, KAKENHI-PROJECT-16K09745, KAKENHI-PROJECT-16K09778
[Journal Article] Mechanisms of fat-induced gastric inhibitory polypeptide/glucose-dependent insulinotropic polypeptide secretion from K cells.2016
- Author(s)
  Yamane S, Harada N, Inagaki N.
- Journal Title
  
  J Diabetes Investig.
  
  Volume: 7 Issue: S1 Pages: 20-20
- DOI
  10.1111/jdi.12467
- NAID
  120005770746
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05326, KAKENHI-PROJECT-16K09745
[Journal Article] Control of intestinal stem cell fate: A novel approach to treating diabetes2016
- Author(s)
  Yamane S, Inagaki N
- Journal Title
  
  J Diabetes Investig.
  
  Volume: 7 Issue: 2 Pages: 166-8
- DOI
  10.1111/jdi.12390
- NAID
  120005770741
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26860695
[Journal Article] Enteral supplement enriched with glutamine, fiber, and oligosaccharide modulates incretin and glucagon-like peptide-2 secretion.2015
- Author(s)
  Joo E., Muraoka A., Hamasaki A., Harada N., Yamane S., Kondo Y., Suzuki K., Nasteska D., Shibue K., Harada T., Iwasaki K., Tsuji H., Shide K., Inagaki N.
- Journal Title
  
  J Diabetes Investig.
  
  Volume: 6 Issue: 3 Pages: 302-308
- DOI
  10.1111/jdi.12289
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461345, KAKENHI-PROJECT-25461344, KAKENHI-PROJECT-26860695, KAKENHI-PROJECT-25293210
[Journal Article] Fatty acid binding protein 5 (FABP5) regulates diet-induced obesity (DIO) via GIP secretion from enteroendocrine K-cells in response to fat ingestion.2015
- Author(s)
  Shibue, K., Yamane, S., Harada, N., Hamasaki, A., Suzuki, K., Joo, E., Iwasaki, K., Nasteska, D., Harada, T., Hayashi, Y., Adachi, Y., Owada, Y., Takayanagi, R. and Inagaki, N.
- Journal Title
  
  Am J Physiol Endocrinol Metab
  
  Volume: 308 Issue: 7 Pages: 583-591
- DOI
  10.1152/ajpendo.00543.2014
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390047, KAKENHI-PROJECT-24659451, KAKENHI-PUBLICLY-25122708, KAKENHI-PROJECT-25670258, KAKENHI-PROJECT-26860695, KAKENHI-PROJECT-26350122, KAKENHI-PROJECT-25461344, KAKENHI-PROJECT-25461345, KAKENHI-PROJECT-25293210, KAKENHI-PROJECT-15H04681
[Journal Article] Free fatty acid receptor GPR120 is highly expressed in enteroendocrine K-cells of upper small intestine and has a critical role in GIP secretion after fat ingestion.2015
- Author(s)
  Iwasaki K, Harada N, Sasaki K, Yamane S, Iida K, Suzuki K, Hamasaki A, Joo E, Nasteska D, Shibue K, Harada T, Hashimoto T, Asakawa Y, Hirasawa A, Inagaki N.
- Journal Title
  
  Endocrinology
  
  Volume: 156 Issue: 3 Pages: 837-837
- DOI
  10.1210/en.2014-1653
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25461344, KAKENHI-PROJECT-25461345, KAKENHI-PROJECT-25670258, KAKENHI-PROJECT-26860695, KAKENHI-PROJECT-25293210
[Presentation] 腸管における脂肪酸受容体GPR120の欠損は高脂肪食摂取下のインスリン抵抗性と脂肪肝を軽減する2023
- Author(s)
  安田拓真, 原田範雄, 波床朋信, 市村敦彦, 池口絵里, 村田由貴, 許林櫻華, 山根俊介, 平澤明, 稲垣暢也.
- Organizer
  第26回日本病態栄養学会年次学術集会
- Data Source
  KAKENHI-PROJECT-20H03731
[Presentation] 腸管に発現する脂肪酸受容体GPR120の機能解析2022
- Author(s)
  安田拓真, 原田範雄, 波床朋信, 市村敦彦, 池口絵里, 村田由貴, 許林櫻華, 山根俊介, 平澤明, 稲垣暢也
- Organizer
  第37回日本糖尿病合併症学会
- Data Source
  KAKENHI-PROJECT-20H03731
[Presentation] 組織透明化による3次元腸管を用いた腸管上皮細胞およびインクレチン分泌細胞の解析2021
- Author(s)
  波床朋信, 原田範雄, 徳本信介, 山根俊介, 池口絵里, 安田拓真, 加藤朋子, 龍岡久登, 桑原智子, 矢部大介, 林良敬, 稲垣暢也
- Organizer
  第64回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-20H03731
[Presentation] コレシストキニンの作用阻害は食欲増加を介して肥満とインスリン抵抗性を誘導する2021
- Author(s)
  許林櫻華, 原田範雄, 村田由貴, 波床朋信, 池口絵里, 加藤朋子, 盧雪セイ, 安田拓真, 山本果奈, 山根俊介, 稲垣暢也
- Organizer
  第64回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-20H03731
[Presentation] 炭酸脱水酵素８ (Car8)によるGLP-1分泌制御機構の解明2021
- Author(s)
  藤原雄太, 山根俊介, 原田範雄, 池口絵理, 岩崎可南子, 鈴木和代, 臼井亮太, 矢部大介, 林良敬, 稲垣暢也
- Organizer
  第64回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-20H03731
[Presentation] CCKレポーターマウスを用いたI細胞における栄養素感知に関わる分子の遺伝子解析2021
- Author(s)
  加藤朋子, 原田範雄, 池口絵理, 三小田亜希子, 波床朋信, 盧雪セイ, 安田拓真, 山根俊介, 稲垣暢也
- Organizer
  第64回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-20H03731
[Presentation] 中鎖脂肪酸トリグリセリドは高脂肪食負荷下のGIP分泌抑制を介して肥満やインスリン抵抗性を軽減する2021
- Author(s)
  池口絵里, 原田範雄, 村田由貴, 波床朋信, 許林櫻華, 盧雪セイ, 安田拓真, 山根俊介, 稲垣暢也
- Organizer
  第64回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-20H03731
[Presentation] 中鎖脂肪酸トリグリセリドはGPR120を介して長鎖脂肪酸トリグリセリド摂取時のGIP分泌を抑制する2021
- Author(s)
  原田範雄, 村田由貴, 岸野重信, 山根俊介, 加藤朋子, 池口絵里, 岩崎可南子, 金丸良徳, 三小田亜希子, 小川順, 平澤明, 稲垣暢也
- Organizer
  第64回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-20H03731
[Presentation] 炭酸脱水酵素８ (Car8)によるGLP-1分泌制御機構の解明2021
- Author(s)
  藤原雄太、山根俊介、原田範雄、池口絵理、岩崎可南子、鈴木和代、臼井亮太、矢部大介、林良敬、稲垣暢也
- Organizer
  第64日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19K08977
[Presentation] 炭酸脱水酵素８ (Car8)によるGLP-1分泌制御機構の解明2019
- Author(s)
  藤原雄太、山根俊介、原田範雄、池口絵理、岩崎可南子、鈴木和代、臼井亮太、矢部大介、林良敬、稲垣暢也
- Organizer
  インクレチン研究会
- Data Source
  KAKENHI-PROJECT-19K08977
[Presentation] インクレチンを介する臓器連関2018
- Author(s)
  稲垣暢也, 山根俊介, 原田範雄.
- Organizer
  日本内分泌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-16H05326
[Presentation] 転写因子Pancreatic duodenal homeobox-1(Pdx1)は加齢に伴うGIP分泌亢進に関与する2018
- Author(s)
  池口絵理, 原田範雄, 金丸良徳, 三小田亜希子, 山根俊介, 岩﨑可南子, 今城正道, 村田由貴, 鈴木和代, 城尾恵里奈, 稲垣暢也.
- Organizer
  第31回日本糖尿病・肥満動物学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05326
[Presentation] Long chain free fatty acid receptor GPR120 mediates oil-induced GIP secretion through CCK in mice.2017
- Author(s)
  Sankoda A, Harada N, Iwasaki K, Yamane S, Murata Y, Shibue K, Thewjitcharoen Y, Suzuki K, Harada T, Kanemaru Y, Shimazu-Kuwahara S, Hirasawa A, Inagaki N.
- Organizer
  Asia Islet Biology and Incretin Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05326
[Presentation] Subcellular Translocation of Fatty Acid-Binding Protein 5 (FABP5) in Glucose-Dependent Insulinotropic Polypeptide (GIP)-Producing K-Cells: Re-Emerging Role of Transmission Electron Microscope2017
- Author(s)
  Kimitaka Shibue, Yotsapon Thewjitcharoen, Shunsuke Yamane, Norio Harada, Takanari Harada, Yuta Fujiwara, Kazuyo Suzuki, Yu Wang, Keiko Furuta, Yuji Owada, Nobuya Inagaki
- Organizer
  ENDO2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09778
[Presentation] 脂肪酸結合タンパク5 (FABP5) の腸管内分泌K細胞における局在に関する検討2017
- Author(s)
  池口絵理渋江公尊Yotsapon Thewjitcharoen 山根俊介原田範雄原田貴成藤原雄太鈴木和代大和田祐二稲垣暢也
- Organizer
  第60回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-16K09778
[Presentation] Role of gastric inhibitory polypeptide (GIP) in high fat diet-induced obesity and insulin resistance.2017
- Author(s)
  Harada N, Yamane S, Inagaki N.
- Organizer
  Asia Islet Biology and Incretin Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05326
[Presentation] 脂肪酸結合タンパク5(FABP5)の腸管内分泌K細胞における局在に関する検討2017
- Author(s)
  池口絵理, 渋江公尊, Thewjitcharoen Yotsapon, 山根俊介, 原田範雄, 原田貴成, 藤原雄太, 鈴木和代, 大和田祐二, 稲垣暢也.
- Organizer
  第60回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-16H05326
[Presentation] インクレチンを介する臓器連関2017
- Author(s)
  稲垣暢也, 山根俊介, 原田範雄.
- Organizer
  第91回日本内分泌学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05326
[Presentation] 卵巣摘出マウスにおけるGIP分泌欠損は体重増加を抑制するが骨量を減少させる2017
- Author(s)
  金丸良徳, 原田範雄, 桑原智子, 植田洋平, 山根俊介, 村田由貴, 八十田明宏, 稲垣暢也.
- Organizer
  第32回日本糖尿病合併症学会年次学術集会
- Data Source
  KAKENHI-PROJECT-16H05326
[Presentation] 長鎖脂肪酸受容体GPR120とGPR40は異なる機序で脂肪摂取時のGIP分泌に関与する2017
- Author(s)
  三小田亜希子, 原田範雄, 岩﨑可南子, 山根俊介, 村田由貴, 金丸良徳, 鈴木和代, 渋江公尊, 原田貴成, 城尾恵里奈, 平澤明, 稲垣暢也.
- Organizer
  第60回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-16H05326
[Presentation] FABP5 is an essential modulator of fatty acid-induced GIP secretion in enteroendocrine K cells2017
- Author(s)
  Shunsuke Yamane
- Organizer
  3rd Korea-Japan Diabetes Forum
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09778
[Presentation] Glucose-dependent insulinotropic polypeptide (GIP) deficiency improves obesity but worsens bone loss in ovariectomised mice2017
- Author(s)
  Kanemaru Y, Harada N, Kuwahara-Shimazu S, Ueda Y, Yamane S, Murata Y, Yasoda A, Kieffer TJ, Inagaki N.
- Organizer
  53rd EASD Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05326
[Presentation] 過食肥満下におけるインクレチンGIPの生体内への影響について2017
- Author(s)
  桑原智子, 原田範雄, 金丸良徳, 山根俊介, 村田由貴, 三小田亜希子, 岩崎可南子, 城尾恵里奈, 渋江公尊, 原田貴成, 池口絵理, 藤原雄太, 稲垣暢也.
- Organizer
  第60回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-16H05326
[Presentation] Inhibition of GIP receptor signaling in adipose tissue reduces insulin resistance and improves hepatic steatosis in high fat diet-induced obesity2015
- Author(s)
  Erina Joo,Norio Harada, Shunsuke Yamane, Toru Fukushima, Daisuke Taura, Kanako Iwasaki, Akiko Sankoda, Yuki Murata, Kimitaka Shibue, Kazuyo Suzuki, Takanari Harada, Satoko Kuwahara, Yuta Fujiwara, Nobuya Inagaki
- Organizer
  Incretin 2015
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2015-07-31
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860695
[Presentation] 脂肪酸結合タンパク質５（ＦＡＢＰ５）は胆汁の作用を介したＫ細胞における脂肪誘導性ＧＩＰ分泌の制御に関与する2015
- Author(s)
  渋江公尊　山根俊介　原田範雄　濱崎暁洋　鈴木和代　城尾恵理奈　岩﨑可南子　ダニエラナステスカ　原田貴成　安達泰弘　大和田祐二　高栁涼一　稲垣暢也
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  下関市
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26860695
[Presentation] Fatty acid-binding protein 5 regulates diet-induced obesity via GIP secretion from enteroendocrine K cells in response to fat ingestion2015
- Author(s)
  Kimitaka Shibue,Shunsuke Yamane,Norio Harada,Akihiro Hamasaki,Kazuyo Suzuki, Erina Joo, Kanako Iwasaki, Daniela Nasteska, Takanari Harada, Yoshitaka Hayashi, Yasuhiro Adachi, Yuji Owada, Ryoichi Takayanagi, Nobuya Inagaki
- Organizer
  The American Diabetes Association’s 7５th Scientific Sessions
- Place of Presentation
  Boston, MA
- Year and Date
  2015-06-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860695
[Presentation] Fatty acid-binding protein 5 regulates diet-induced obesity via GIP secretion from enteroendocrine K-cells in response to fat ingestion2015
- Author(s)
  Kimitaka Shibue,Shunsuke Yamane,Norio Harada, Akihiro Hamasaki, Kazuyo Suzuki, Erina Joo, Kanako Iwasaki, Daniela Nasteska, Takanari Harada, Yoshitaka Hayashi, Yasuhiro Adachi, Yuji Owada, Ryoichi Takayanagi, Nobuya Inagaki
- Organizer
  Incretin 2015
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2015-07-31
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860695
[Presentation] 脂肪酸受容体ＧＰＲ１２０は上部小腸Ｋ細胞に高発現し脂肪摂取後のＧＩＰ分泌に深く関与する2015
- Author(s)
  岩﨑可南子　原田範雄　佐々木香月　山根俊介　飯田桂子　濵崎暁洋　鈴木和代　城尾恵理奈　ナステスカダニエラ　渋江公尊　原田貴成　平澤明　稲垣暢也
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  下関市
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26860695
[Presentation] Free fatty acid receptor GPR120 is highly expressed in enteroendocrine K-cells of upper small intestine and has a critical role in GIP secretion after fat ingestion2015
- Author(s)
  Takanari Harada, Kanako Iwasaki,Norio Harada, Kazuki Sasaki, Shunsuke Yamane, Keiko Iida, Kazuyo Suzuki, Akihiro Hamasaki, Daniela Nasteska, Kimitaka Shibue, Erina Joo,Toshihiro Hashimoto, Yoshinori, Asakawa, Akira Hirasawa, Nobuya Inagaki
- Organizer
  Incretin 2015
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2015-07-31
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860695
[Presentation] 脂肪酸結合タンパク質５（ＦＡＢＰ５）はＫ細胞における脂肪誘導性ＧＩＰ分泌の制御に関与する2014
- Author(s)
  渋江公尊、山根俊介、原田範雄、濱崎暁洋、鈴木和代、城尾恵里奈、岩崎可南子、ダニエラナステスカ、原田貴成、安達泰弘、大和田祐二、高栁涼一、稲垣暢也
- Organizer
  第26回分子糖尿病学シンポジウム
- Place of Presentation
  高知市文化プラザ
- Year and Date
  2014-12-06
- Data Source
  KAKENHI-PROJECT-26860695
[Presentation] FABP5 is an essential modulator of fatty acid-induced GIP secretion in enteroendocrine K cells
- Author(s)
  Kimitaka Shibue, Shunsuke Yamane, Norio Harada, Akihiro Hamasaki, Kazuyo Suzuki, Erina Joo, Kanako Iwasaki, Daniela Nasteska Takanari Harada, Yasuhiro Adachi, Yuji Owada, Ryoichi Takayanagi, Nobuya Inagaki
- Organizer
  50th EASD Annual Meeting
- Place of Presentation
  Wien, Austria
- Year and Date
  2014-09-16 – 2014-09-19
- Data Source
  KAKENHI-PROJECT-26860695
[Presentation] 脂肪酸結合タンパク質５（ＦＡＢＰ５）はＫ細胞における脂肪誘導性ＧＩＰ分泌の制御に関与する
- Author(s)
  渋江公尊、山根俊介、原田範雄、濱崎暁洋、鈴木和代、城尾恵里奈、岩崎可南子、ダニエラナステスカ、原田貴成、安達泰弘、大和田祐二、高栁涼一、稲垣暢也
- Organizer
  第29回日本糖尿病・肥満動物学会
- Place of Presentation
  京都大学医学部芝蘭会館
- Year and Date
  2015-02-13 – 2015-02-14
- Data Source
  KAKENHI-PROJECT-26860695

1. Inagaki Nobuya (30241954)

# of Collaborated Projects: 3 results

# of Collaborated Products: 27 results
2. 原田範雄 (50530169)

# of Collaborated Projects: 3 results

# of Collaborated Products: 30 results
3. 林良敬 (80420363)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
4. 大高章 (20201973)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. HAMAZAKI Akihiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 桑原智子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 大和田祐二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yamane Syunsuke 山根 俊介

YAMANE Shunsuke 山根 俊介

Research Projects

Research Products

Co-Researchers

GIP/GLP-1受容体共刺激による血糖降下・体重減少作用増強メカニズムの解明

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電位依存性Ca2+チャネルα2δサブユニットを介したGLP-1分泌制御機構の解明Principal Investigator

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Integrated analysis of enteroendocrine hormone secretion mechanisms involved in nutrient sensing

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Elucidation of the regulatory mechanism of GLP-1 secretion by carbonic anhydrase 8 (Car8)Principal Investigator

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Analysis of the mechanisms of incretin secretion: similarities or differences of GIP and GLP-1 secretion

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Investigation of regulatory mechanisim of GIP secretion by fatty-acid binding protein 5 (FABP5)Principal Investigator

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Functional analysis of transcription factor Rfx6 in GIP-producing K-cellPrincipal Investigator

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[Journal Article] Inhibition of GPR120 signaling in intestine ameliorates insulin resistance and fatty liver under high-fat diet feeding2023

Author(s)

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DOI

Data Source

[Journal Article] Carbonic anhydrase 8 (CAR8) negatively regulates GLP-1 secretion from enteroendocrine cells in response to long-chain fatty acids.2021

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[Journal Article] Gene expression of nutrient-sensing molecules in I cells of CCK reporter male mice2021

Author(s)

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DOI

Data Source

[Journal Article] Carbonic anhydrase 8 (CAR8) negatively regulates GLP-1 secretion from enteroendocrine cells in response to long-chain fatty acids2021

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[Journal Article] Medium-chain triglycerides inhibit long-chain triglyceride-induced GIP secretion through GPR120-dependent inhibition of CCK.2021

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[Journal Article] Medium-chain triglyceride diet stimulates less GIP secretion and suppresses body weight and fat mass gain compared with long-chain triglyceride diet.2019

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[Journal Article] Free fatty acid receptor GPR120 and GPR40 are essential for oil-induced GIP secretion.2019

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[Journal Article] Glucose-dependent insulinotropic polypeptide deficiency reduced fat accumulation and insulin resistance, but deteriorated bone loss in ovariectomized mice2018

Yamane Syunsuke 山根俊介

YAMANE Shunsuke 山根俊介