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Fukushima Yuji  福島 祐二

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… Alternative Names

福島 祐二  フクシマ ユウジ

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Researcher Number 90583146
Other IDs
Affiliation (Current) 2025: 京都大学, 医学研究科, 特定助教
Affiliation (based on the past Project Information) *help 2022 – 2024: 京都大学, 医学研究科, 特定助教
2018 – 2019: 京都大学, 医学研究科, 特定助教
2016 – 2017: 京都大学, 医学研究科, 研究員
2014 – 2015: 京都大学, 医学(系)研究科(研究院), 研究員
Review Section/Research Field
Principal Investigator
Basic Section 51030:Pathophysiologic neuroscience-related / Medium-sized Section 50:Oncology and related fields
Except Principal Investigator
Veterinary medical science / Medium-sized Section 42:Veterinary medical science, animal science, and related fields / Integrative animal science
Keywords
Principal Investigator
in vivoイメージング / CAR-T細胞 / 多発性硬化症 / 加齢変容性リンパ球 / がん / 活性制御 / 非定型TCR / T細胞機能不全
Except Principal Investigator
老化関連T細胞 / CD153 … More / 免疫老化 / CD153リバースシグナル / CD3複合体 / 自己抗体 / 自己免疫疾患 / オステオポンチン / T細胞 / SLE / 老化 / 免疫学 / TCRシグナル阻害 / CD163-CD30相互作用 / TCRシグナル抑制 / 加齢関連疾患 / リバースシグナル / CD30 / CD30L / アジュバント / 免疫チェックポイント分子 / メモリーT細胞 / miR181a / 胚中心 / 貪食 / 死細胞処理 / 全身性エリテマトーデス / PD-1 Less
  • Research Projects

    (5 results)
  • Research Products

    (13 results)
  • Co-Researchers

    (5 People)
  •  加齢変容性リンパ球が介在する多発性硬化症の病態機序解明とその制御Principal Investigator

    • Principal Investigator
      福島 祐二
    • Project Period (FY)
      2024 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 51030:Pathophysiologic neuroscience-related
    • Research Institution
      Kyoto University
  •  非定型TCR複合体を形成する機能不全耐性T細胞集団の作出とがん治療への応用Principal Investigator

    • Principal Investigator
      福島 祐二
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 50:Oncology and related fields
    • Research Institution
      Kyoto University
  •  Study on a new ajuvant that induce memory T cells efficiently

    • Principal Investigator
      Hattori Masakazu
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 42:Veterinary medical science, animal science, and related fields
    • Research Institution
      Kyoto University
  •  Control of senescence-associated T cell-induction

    • Principal Investigator
      Hattori Masakazu
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Veterinary medical science
    • Research Institution
      Kyoto University
  •  Study on the mechanism(s) of immunosenescence and its application for vaccine development.

    • Principal Investigator
      HATTORI Masakazu
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Integrative animal science
    • Research Institution
      Kyoto University

All 2024 2023 2022 2018 2017 2016 2015 Other

All Journal Article Presentation

  • [Journal Article] T細胞の加齢変化と老化関連T細胞の病理学的関与2023

    • Author(s)
      福島祐二、服部雅一
    • Journal Title

      臨床免疫・アレルギー科

      Volume: 79 Pages: 8-14

    • Data Source
      KAKENHI-PROJECT-22K19455
  • [Journal Article] Protocol for the isolation of mouse senescence-associated CD4+ T cells using flow cytometry and functional assays2023

    • Author(s)
      Fukushima Yuji、Minato Nagahiro、Hattori Masakazu
    • Journal Title

      STAR Protocols

      Volume: 4 Issue: 3 Pages: 102472-102472

    • DOI

      10.1016/j.xpro.2023.102472

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K19455
  • [Journal Article] cis interaction of CD153 with TCR/CD3 is crucial for the pathogenic activation of senescence-associated T cells2022

    • Author(s)
      Fukushima Yuji、Sakamoto Keiko、Matsuda Michiyuki、Yoshikai Yasunobu、Yagita Hideo、Kitamura Daisuke、Chihara Misaki、Minato Nagahiro、Hattori Masakazu
    • Journal Title

      Cell Reports

      Volume: 40 Issue: 12 Pages: 111373-111373

    • DOI

      10.1016/j.celrep.2022.111373

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K19455, KAKENHI-PROJECT-20K21533
  • [Journal Article] The impact of senescence-associated T cells on immunosenescence and age-related disorders.2018

    • Author(s)
      Fukushima Y, Minato N, Hattori M
    • Journal Title

      Inflammation and Regeneration

      Volume: 38 Issue: 1 Pages: 24-30

    • DOI

      10.1186/s41232-018-0082-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K19268, KAKENHI-PROJECT-17H03925
  • [Journal Article] The potential role of Osteopontin in the maintenance of commensal bacteria homeostasis in the intestine.2017

    • Author(s)
      Ito K, Nakajima A1, Fukushima Y1, Suzuki K1, Sakamoto K, Hamazaki Y, Ogasawara K, Minato N, and Hattori M.
    • Journal Title

      PLoS One.

      Volume: 12 Issue: 3 Pages: e0173629-e0173629

    • DOI

      10.1371/journal.pone.0173629

    • NAID

      120006488574

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-24111008, KAKENHI-PLANNED-16H06497, KAKENHI-PROJECT-16H05530, KAKENHI-PROJECT-26450443, KAKENHI-PROJECT-15K19075, KAKENHI-PROJECT-15K15151, KAKENHI-PUBLICLY-15H01154, KAKENHI-PROJECT-17H03925
  • [Journal Article] Osteopontin in spontaneous germinal centers inhibits apoptotic cell engulfment and promotes autoantibody production in lupus mice.2016

    • Author(s)
      Sakamoto、K., Fukushima、Y., Itoh、K., Matsuda, M., Nagata, S., Minato, N., and Hattori, M.
    • Journal Title

      J. Immunol.

      Volume: 197 Issue: 6 Pages: 2177-2186

    • DOI

      10.4049/jimmunol.1600987

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-24111008, KAKENHI-PROJECT-26450443, KAKENHI-PROJECT-15K19075, KAKENHI-PROJECT-15H05785
  • [Journal Article] A CD153+CD4+ T follicular cell population with cell-senescence features plays a crucial role in lupus pathogenesis via osteopontin production.2015

    • Author(s)
      1.Tahir S, Fukushima Y, Sakamoto K, Sato K, Fujita H, Inoue J, Uede T, Hamazaki Y, Hattori M, Minato N.
    • Journal Title

      The Journal of Immunology

      Volume: 194 Issue: 12 Pages: 5725-5735

    • DOI

      10.4049/jimmunol.1500319

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26450443, KAKENHI-PROJECT-26460066, KAKENHI-PROJECT-15K15151, KAKENHI-PUBLICLY-25111505, KAKENHI-ORGANIZER-24111001, KAKENHI-PROJECT-24590580, KAKENHI-PUBLICLY-15H01154, KAKENHI-PLANNED-24111008
  • [Presentation] Senescence-associated CD4+ T cells and Autoimmune Pathology2024

    • Author(s)
      Yuji Fukushima
    • Organizer
      第52回 日本免疫学会学術集会 国際シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-22K19455
  • [Presentation] 老化関連T細胞と自己免疫疾患2023

    • Author(s)
      福島 祐二
    • Organizer
      第51回 日本臨床免疫学会総会 シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-22K19455
  • [Presentation] CD153-CD30 interaction is involved in immunosenescence of T cells and spontaneous germinal center reactions2016

    • Author(s)
      Fukushima Y, Yamada H, Yoshikai Y, Minato N, Hattori M.
    • Organizer
      日本免疫学会
    • Place of Presentation
      沖縄コンベンションセンター
    • Year and Date
      2016-12-05
    • Data Source
      KAKENHI-PROJECT-26450443
  • [Presentation] Accumulation of naive TMRMlo CD4 T cells promotes generation and functional polarozation of effector cells leading to enhanced germinal center reactions in lupus-prone NZB/W F1 mice.2015

    • Author(s)
      Fukushima Y, Hattori M
    • Organizer
      日本免疫学会
    • Place of Presentation
      札幌コンベンションセンター
    • Year and Date
      2015-11-18
    • Data Source
      KAKENHI-PROJECT-26450443
  • [Presentation] Osteopontin-secreting TCRgd+CD8+ intraepithelial lymphocyte maintains homeostasis of commensal bacteria in the intestine.2015

    • Author(s)
      Ito K, Fukushima Y, Sakamoto K, Minato N, Hattori M
    • Organizer
      日本免疫学会
    • Place of Presentation
      札幌コンベンションセンター
    • Year and Date
      2015-11-18
    • Data Source
      KAKENHI-PROJECT-26450443
  • [Presentation] Senescence associated follicular CD4+ T cell population underlies systemic lupus erythematosus.

    • Author(s)
      Tahir S, Fukushima Y, Sakamoto K, Sato K, Hamazki Y, Hattori M, Minato N.
    • Organizer
      日本免疫学会
    • Place of Presentation
      京都国際会議場
    • Year and Date
      2014-12-10 – 2014-12-12
    • Data Source
      KAKENHI-PROJECT-26450443
  • 1.  HATTORI Masakazu (40211479)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 6 results
  • 2.  MASHIMO Tomoji (80397554)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  保富 康宏 (90281724)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  木村 公俊 (10807093)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  湊 長博
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results

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