Fukushima Yuji 福島祐二

… Alternative Names

福島祐二フクシマユウジ

Less

Researcher Number	90583146
Other IDs
Affiliation (Current)	2025: 京都大学, 医学研究科, 特定助教
Affiliation (based on the past Project Information) *help	2022 – 2024: 京都大学, 医学研究科, 特定助教 2018 – 2019: 京都大学, 医学研究科, 特定助教 2016 – 2017: 京都大学, 医学研究科, 研究員 2014 – 2015: 京都大学, 医学(系)研究科(研究院), 研究員
Review Section/Research Field	Principal Investigator Basic Section 51030:Pathophysiologic neuroscience-related / Medium-sized Section 50:Oncology and related fields Except Principal Investigator Veterinary medical science / Medium-sized Section 42:Veterinary medical science, animal science, and related fields / Integrative animal science
Keywords	Principal Investigator in vivoイメージング / CAR-T細胞 / 多発性硬化症 / 加齢変容性リンパ球 / がん / 活性制御 / 非定型TCR / T細胞機能不全 Except Principal Investigator 老化関連T細胞 / CD153 … More / 免疫老化 / CD153リバースシグナル / CD3複合体 / 自己抗体 / 自己免疫疾患 / オステオポンチン / T細胞 / SLE / 老化 / 免疫学 / TCRシグナル阻害 / CD163-CD30相互作用 / TCRシグナル抑制 / 加齢関連疾患 / リバースシグナル / CD30 / CD30L / アジュバント / 免疫チェックポイント分子 / メモリーT細胞 / miR181a / 胚中心 / 貪食 / 死細胞処理 / 全身性エリテマトーデス / PD-1 Less

加齢変容性リンパ球が介在する多発性硬化症の病態機序解明とその制御Principal Investigator
- Principal Investigator
  
  福島祐二
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Kyoto University
非定型TCR複合体を形成する機能不全耐性T細胞集団の作出とがん治療への応用Principal Investigator
- Principal Investigator
  
  福島祐二
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  Kyoto University
Study on a new ajuvant that induce memory T cells efficiently
- Principal Investigator
  
  Hattori Masakazu
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 42:Veterinary medical science, animal science, and related fields
- Research Institution
  Kyoto University
Control of senescence-associated T cell-induction
- Principal Investigator
  
  Hattori Masakazu
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Veterinary medical science
- Research Institution
  Kyoto University
Study on the mechanism(s) of immunosenescence and its application for vaccine development.
- Principal Investigator
  
  HATTORI Masakazu
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Integrative animal science
- Research Institution
  Kyoto University

All 2024 2023 2022 2018 2017 2016 2015 Other

All Journal Article Presentation

[Journal Article] T細胞の加齢変化と老化関連T細胞の病理学的関与2023
- Author(s)
  福島祐二、服部雅一
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 79 Pages: 8-14
- Data Source
  KAKENHI-PROJECT-22K19455
[Journal Article] Protocol for the isolation of mouse senescence-associated CD4+ T cells using flow cytometry and functional assays2023
- Author(s)
  Fukushima Yuji、Minato Nagahiro、Hattori Masakazu
- Journal Title
  
  STAR Protocols
  
  Volume: 4 Issue: 3 Pages: 102472-102472
- DOI
  10.1016/j.xpro.2023.102472
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19455
[Journal Article] cis interaction of CD153 with TCR/CD3 is crucial for the pathogenic activation of senescence-associated T cells2022
- Author(s)
  Fukushima Yuji、Sakamoto Keiko、Matsuda Michiyuki、Yoshikai Yasunobu、Yagita Hideo、Kitamura Daisuke、Chihara Misaki、Minato Nagahiro、Hattori Masakazu
- Journal Title
  
  Cell Reports
  
  Volume: 40 Issue: 12 Pages: 111373-111373
- DOI
  10.1016/j.celrep.2022.111373
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19455, KAKENHI-PROJECT-20K21533
[Journal Article] The impact of senescence-associated T cells on immunosenescence and age-related disorders.2018
- Author(s)
  Fukushima Y, Minato N, Hattori M
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: 38 Issue: 1 Pages: 24-30
- DOI
  10.1186/s41232-018-0082-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19268, KAKENHI-PROJECT-17H03925
[Journal Article] The potential role of Osteopontin in the maintenance of commensal bacteria homeostasis in the intestine.2017
- Author(s)
  Ito K, Nakajima A1, Fukushima Y1, Suzuki K1, Sakamoto K, Hamazaki Y, Ogasawara K, Minato N, and Hattori M.
- Journal Title
  
  PLoS One.
  
  Volume: 12 Issue: 3 Pages: e0173629-e0173629
- DOI
  10.1371/journal.pone.0173629
- NAID
  120006488574
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-24111008, KAKENHI-PLANNED-16H06497, KAKENHI-PROJECT-16H05530, KAKENHI-PROJECT-26450443, KAKENHI-PROJECT-15K19075, KAKENHI-PROJECT-15K15151, KAKENHI-PUBLICLY-15H01154, KAKENHI-PROJECT-17H03925
[Journal Article] Osteopontin in spontaneous germinal centers inhibits apoptotic cell engulfment and promotes autoantibody production in lupus mice.2016
- Author(s)
  Sakamoto、K., Fukushima、Y., Itoh、K., Matsuda, M., Nagata, S., Minato, N., and Hattori, M.
- Journal Title
  
  J. Immunol.
  
  Volume: 197 Issue: 6 Pages: 2177-2186
- DOI
  10.4049/jimmunol.1600987
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-24111008, KAKENHI-PROJECT-26450443, KAKENHI-PROJECT-15K19075, KAKENHI-PROJECT-15H05785
[Journal Article] A CD153+CD4+ T follicular cell population with cell-senescence features plays a crucial role in lupus pathogenesis via osteopontin production.2015
- Author(s)
  1.Tahir S, Fukushima Y, Sakamoto K, Sato K, Fujita H, Inoue J, Uede T, Hamazaki Y, Hattori M, Minato N.
- Journal Title
  
  The Journal of Immunology
  
  Volume: 194 Issue: 12 Pages: 5725-5735
- DOI
  10.4049/jimmunol.1500319
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26450443, KAKENHI-PROJECT-26460066, KAKENHI-PROJECT-15K15151, KAKENHI-PUBLICLY-25111505, KAKENHI-ORGANIZER-24111001, KAKENHI-PROJECT-24590580, KAKENHI-PUBLICLY-15H01154, KAKENHI-PLANNED-24111008
[Presentation] Senescence-associated CD4+ T cells and Autoimmune Pathology2024
- Author(s)
  Yuji Fukushima
- Organizer
  第５２回日本免疫学会学術集会国際シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-22K19455
[Presentation] 老化関連T細胞と自己免疫疾患2023
- Author(s)
  福島　祐二
- Organizer
  第５１回日本臨床免疫学会総会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-22K19455
[Presentation] CD153-CD30 interaction is involved in immunosenescence of T cells and spontaneous germinal center reactions2016
- Author(s)
  Fukushima Y, Yamada H, Yoshikai Y, Minato N, Hattori M.
- Organizer
  日本免疫学会
- Place of Presentation
  沖縄コンベンションセンター
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-26450443
[Presentation] Accumulation of naive TMRMlo CD4 T cells promotes generation and functional polarozation of effector cells leading to enhanced germinal center reactions in lupus-prone NZB/W F1 mice.2015
- Author(s)
  Fukushima Y, Hattori M
- Organizer
  日本免疫学会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-26450443
[Presentation] Osteopontin-secreting TCRgd+CD8+ intraepithelial lymphocyte maintains homeostasis of commensal bacteria in the intestine.2015
- Author(s)
  Ito K, Fukushima Y, Sakamoto K, Minato N, Hattori M
- Organizer
  日本免疫学会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-26450443
[Presentation] Senescence associated follicular CD4+ T cell population underlies systemic lupus erythematosus.
- Author(s)
  Tahir S, Fukushima Y, Sakamoto K, Sato K, Hamazki Y, Hattori M, Minato N.
- Organizer
  日本免疫学会
- Place of Presentation
  京都国際会議場
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-26450443

1. HATTORI Masakazu (40211479)

# of Collaborated Projects: 4 results

# of Collaborated Products: 6 results
2. MASHIMO Tomoji (80397554)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 保富康宏 (90281724)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 木村公俊 (10807093)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 湊長博

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Fukushima Yuji 福島 祐二

福島 祐二 フクシマ ユウジ

Research Projects

Research Products

Co-Researchers

加齢変容性リンパ球が介在する多発性硬化症の病態機序解明とその制御Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

非定型TCR複合体を形成する機能不全耐性T細胞集団の作出とがん治療への応用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study on a new ajuvant that induce memory T cells efficiently

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Control of senescence-associated T cell-induction

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on the mechanism(s) of immunosenescence and its application for vaccine development.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] T細胞の加齢変化と老化関連T細胞の病理学的関与2023

Author(s)

Journal Title

Data Source

[Journal Article] Protocol for the isolation of mouse senescence-associated CD4+ T cells using flow cytometry and functional assays2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] cis interaction of CD153 with TCR/CD3 is crucial for the pathogenic activation of senescence-associated T cells2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The impact of senescence-associated T cells on immunosenescence and age-related disorders.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The potential role of Osteopontin in the maintenance of commensal bacteria homeostasis in the intestine.2017

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Osteopontin in spontaneous germinal centers inhibits apoptotic cell engulfment and promotes autoantibody production in lupus mice.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A CD153+CD4+ T follicular cell population with cell-senescence features plays a crucial role in lupus pathogenesis via osteopontin production.2015

Author(s)

Journal Title

DOI

Data Source

[Presentation] Senescence-associated CD4+ T cells and Autoimmune Pathology2024

Author(s)

Organizer

Data Source

[Presentation] 老化関連T細胞と自己免疫疾患2023

Author(s)

Organizer

Data Source

[Presentation] CD153-CD30 interaction is involved in immunosenescence of T cells and spontaneous germinal center reactions2016

Author(s)

Fukushima Yuji 福島祐二

福島祐二フクシマユウジ