OHKO Kentaro 大湖健太郎

Researcher Number	90595274
Other IDs	https://orcid.org/0000-0002-7614-126X
Affiliation (Current)	2024: 高知大学, 医学部, 客員講師
Affiliation (based on the past Project Information) *help	2024: 高知大学, 医学部, 客員講師 2023: 高知大学, 教育研究部医療学系臨床医学部門, 助教 2015 – 2019: 高知大学, 教育研究部医療学系臨床医学部門, 助教 2013 – 2014: 高知大学, 教育研究部医療学系, 助教
Review Section/Research Field	Principal Investigator Dermatology / Basic Section 53050:Dermatology-related Except Principal Investigator Dermatology
Keywords	Principal Investigator 乾癬 / 免疫チェックポイント阻害分子 / 単球 / VISTA/PD-1H / 毛乳頭 / 毛髪 / 乏毛症 / Cantu症候群 / KATP チャネル / KATP　チャンネル … More / SUR2B遺伝子 / dermal papillae / 毛乳頭細胞 / 多毛症 / Hypotrichosis / Hypertrichosis / Minoxidil / Cantu Syndrome / Dermal papilla / インターロイキン36 / インターロイキン / 皮膚科学 / 膿疱性乾癬 / 好中球 / 炎症性角化症 / 樹状細胞 / ケラチノサイト / IL-17C / 膿疱 / IL-36 … More Except Principal Investigator 自然免疫 / 紫外線照射 / トール様受容体 / 膠原病 / T細胞 / 紫外線 / 皮膚癌 Less

乾癬単球に発現する免疫チェックポイント分子PD-1H/VISTAは心血管合併症へ寄与するか?Principal Investigator
- Principal Investigator
  
  大湖健太郎
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Kochi University
The analysis about the new epithelial-mesenchymal crosstalk using hereditary hypertrichosis-derived papilla cells.Principal Investigator
- Principal Investigator
  
  大湖健太郎
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Kochi University
The effect of UV irradiation on development of systemic lupus in mouse model
- Principal Investigator
  
  SANO SHIGETOSHI
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Dermatology
- Research Institution
  Kochi University
Psoriasis like phenotype in K5.Stat3C transgenic mice depends on the IL-23/Th17 axis through interleukin 36R signalsPrincipal Investigator
- Principal Investigator
  
  OHKO Kentaro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Kochi University
紫外線発癌におけるＴ細胞の関与について
- Principal Investigator
  
  喜多川千恵
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Kochi University

All 2020 2017 2016 2015 2014 Other

All Journal Article Presentation

[Journal Article] Skin and hair abnormalities of Cantu syndrome: A congenital hypertrichosis due to a genetic alteration mimicking the pharmacological effect of minoxidil2020
- Author(s)
  Kentaro OHKO, Kimiko NAKAJIMA, Hideki NAKAJIMA, Yoko HIRAKI, Kazuo KUBOTA, Toshiyuki FUKAO, Satoko MIYATAKE, Naomichi MATSUMOTO, Shigetoshi SANO
- Journal Title
  
  Journal of Dermatology
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10211
[Journal Article] IL-36シグナルを介した表皮細胞-樹状細胞間クロストークによる乾癬発症機序の解明2015
- Author(s)
  大湖健太郎, 中島喜美子, 佐野栄紀
- Journal Title
  
  角化症研究会記録集
  
  Volume: 29 Pages: 112-115
- Data Source
  KAKENHI-PROJECT-26461695
[Presentation] 遺伝性多毛症Cantu症候群の毛包における組織学的検討2017
- Author(s)
  大湖健太郎、中島英貴、柴田夕夏、中島喜美子、佐野栄紀
- Organizer
  第116回日本皮膚科学会総会
- Data Source
  KAKENHI-PROJECT-17K10211
[Presentation] The three cases of Cantu syndrome,a congenital hypertrichosis with the similar condition to minoxidil use2017
- Author(s)
  Ohko K, Nakajima K, Shibata Y, Nakajima H, Hiraki Y, Toyoshima K, Tsuji T, Sano S.
- Organizer
  10th World Congress for Hair Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10211
[Presentation] Regnase-1 in keratinocytes limits the IL-36/IL-36R auto-stimulatory loop to buffer skin inflammation.2017
- Author(s)
  Sano S, Ohko K,　Satoh　T, Akira　S, Takaishi　M.
- Organizer
  The42nd Annual Meeting of the Japanese Society for Investigative Dermatology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04888
[Presentation] Psoriasis development is required for cooperative IL-36R signal in dendritic cells and keratinocytes2016
- Author(s)
  Kentaro Ohko, Kimiko Nakajima, Shigetoshi Sano
- Organizer
  Society of Investigative Dermatology annual meeting
- Place of Presentation
  Scottsdale, Arizona, America
- Year and Date
  2016-05-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461695
[Presentation] Kinetic of two distinct diseases induced by topical treatment with imiquimod cream in mice: skin inflammation and systemic autoimmunity2015
- Author(s)
  Sayo Kataoka, Mayuko Yamamot, Kentaro Ohko, Reiko Kamijima, Chisa Matsuoka, Shigetoshi Sano
- Organizer
  日本研究皮膚科学会第40回年次学術大会・総会 (JSID)
- Place of Presentation
  岡山コンベンションセンター（岡山）
- Year and Date
  2015-12-11
- Data Source
  KAKENHI-PROJECT-15H04888
[Presentation] IL-36シグナルを介した表皮細胞―樹状細胞間クロストークによる乾癬発症機序の解明2015
- Author(s)
  大湖健太郎、中島喜美子、佐野栄紀
- Organizer
  日本皮膚科学会新潟地方会　第377回例会
- Place of Presentation
  ホテルオークラ新潟（新潟）
- Year and Date
  2015-04-25
- Data Source
  KAKENHI-PROJECT-26461695
[Presentation] Keratinocyte-autonomous IL-36/IL-17C loop shapes the psoriasiform phenotype2015
- Author(s)
  Kentaro Ohko, Kimiko Nakajima, Shigetoshi Sano
- Organizer
  45th European Society for Dermatological Research
- Place of Presentation
  The Beurs-World Trade Center (The Netherlands)
- Year and Date
  2015-09-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461695
[Presentation] IL-36RN遺伝子変異を持つ膿疱性乾癬患者に生じたメトトレキサート関連リンパ増殖症の1例2015
- Author(s)
  大湖健太郎、中島喜美子、砥谷和人、笹部衣里、杉浦一充、秋山真志、佐野栄紀
- Organizer
  第114回日本皮膚科学会総会
- Place of Presentation
  パシフィコ横浜(横浜）
- Year and Date
  2015-05-29
- Data Source
  KAKENHI-PROJECT-26461695
[Presentation] IL-36 signaling is a gatekeeper for both keratinocytes and dendritic cells linking innate immunity to psoriatic nature2014
- Author(s)
  大湖健太郎，中島喜美子，佐野栄紀
- Organizer
  第28回表皮細胞研究会
- Place of Presentation
  城山観光ホテル（鹿児島市）
- Year and Date
  2014-12-06
- Data Source
  KAKENHI-PROJECT-26461695
[Presentation] IL-36シグナルを介した表皮細胞-樹状細胞間クロストークによる乾癬発症機序の解明2014
- Author(s)
  大湖健太郎，中島喜美子，佐野栄紀
- Organizer
  第21回四国四大学皮膚研究会
- Place of Presentation
  ホテルグランドパレス徳島（徳島市）
- Year and Date
  2014-06-28
- Data Source
  KAKENHI-PROJECT-26461695
[Presentation] IL-36シグナルを介した表皮細胞-樹状細胞間クロストークによる乾癬発症機序の解明2014
- Author(s)
  大湖健太郎，中島喜美子，佐野栄紀
- Organizer
  第29回角化症研究会
- Place of Presentation
  東京商工会議所（東京都）
- Year and Date
  2014-08-02
- Data Source
  KAKENHI-PROJECT-26461695
[Presentation] IL-36シグナルを介した表皮細胞-樹状細胞間クロストークによる乾癬発症機序の解明
- Author(s)
  大湖健太郎，中島喜美子，佐野栄紀
- Organizer
  第29回日本乾癬学会
- Place of Presentation
  高知市文化プラザ　カルポート（高知市）
- Year and Date
  2014-09-19 – 2014-09-20
- Data Source
  KAKENHI-PROJECT-26461695
[Presentation] IL-36 signaling is a gatekeeper for both keratinocytes and dendritic cells linking innate immunity to psoriatic nature
- Author(s)
  Kentaro Ohko, Kimiko Nakajima, Shigetoshi Sano
- Organizer
  The 39th Annual Meeting of the Japanese Society for Investigative Dermatology
- Place of Presentation
  Hotel Hankyu Expo Park Osaka
- Year and Date
  2014-12-12 – 2014-12-14
- Data Source
  KAKENHI-PROJECT-26461695
[Presentation] IL-36シグナルを介した表皮細胞-樹状細胞間クロストークによる乾癬発症機序の解明
- Author(s)
  大湖健太郎，中島喜美子，佐野栄紀
- Organizer
  第113回日本皮膚科学会総会
- Place of Presentation
  京都国際会議場（京都市）
- Year and Date
  2014-05-30 – 2014-06-01
- Data Source
  KAKENHI-PROJECT-26461695

1. SANO SHIGETOSHI (80273621)

# of Collaborated Projects: 4 results

# of Collaborated Products: 16 results
2. 中島喜美子 (20403892)

# of Collaborated Projects: 4 results

# of Collaborated Products: 14 results
3. 高石樹朗 (10303223)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. MIYAKE Kensuke (60229812)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 喜多川千恵 (60527589)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 横川真紀 (40346721)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 樽谷勝仁 (30301261)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 山本真有子 (20423478)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 寺石美香 (40437736)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 石元達士 (40750039)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 中井浩三 (40363204)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

OHKO Kentaro 大湖 健太郎

Research Projects

Research Products

Co-Researchers

乾癬単球に発現する免疫チェックポイント分子PD-1H/VISTAは心血管合併症へ寄与するか?Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The analysis about the new epithelial-mesenchymal crosstalk using hereditary hypertrichosis-derived papilla cells.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The effect of UV irradiation on development of systemic lupus in mouse model

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Psoriasis like phenotype in K5.Stat3C transgenic mice depends on the IL-23/Th17 axis through interleukin 36R signalsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

紫外線発癌におけるＴ細胞の関与について

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Skin and hair abnormalities of Cantu syndrome: A congenital hypertrichosis due to a genetic alteration mimicking the pharmacological effect of minoxidil2020

Author(s)

Journal Title

Data Source

[Journal Article] IL-36シグナルを介した表皮細胞-樹状細胞間クロストークによる乾癬発症機序の解明2015

Author(s)

Journal Title

Data Source

[Presentation] 遺伝性多毛症Cantu症候群の毛包における組織学的検討2017

Author(s)

Organizer

Data Source

[Presentation] The three cases of Cantu syndrome,a congenital hypertrichosis with the similar condition to minoxidil use2017

Author(s)

Organizer

Data Source

[Presentation] Regnase-1 in keratinocytes limits the IL-36/IL-36R auto-stimulatory loop to buffer skin inflammation.2017

Author(s)

Organizer

Data Source

[Presentation] Psoriasis development is required for cooperative IL-36R signal in dendritic cells and keratinocytes2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Kinetic of two distinct diseases induced by topical treatment with imiquimod cream in mice: skin inflammation and systemic autoimmunity2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] IL-36シグナルを介した表皮細胞―樹状細胞間クロストークによる乾癬発症機序の解明2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Keratinocyte-autonomous IL-36/IL-17C loop shapes the psoriasiform phenotype2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] IL-36RN遺伝子変異を持つ膿疱性乾癬患者に生じたメトトレキサート関連リンパ増殖症の1例2015

Author(s)

OHKO Kentaro 大湖健太郎