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JOSHITA SATORU  城下 智

… Alternative Names

城下 智  ジョウシタ サトル

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Researcher Number 90597965
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-6364-9654
Affiliation (Current) 2025: 信州大学, 医学部, 特任教授
Affiliation (based on the past Project Information) *help 2025: 信州大学, 医学部, 特任教授
2023 – 2024: 信州大学, 学術研究院医学系, 准教授
2023: 信州大学, 医学部, 特任教授
2020: 信州大学, 学術研究院医学系, 准教授
2016 – 2019: 信州大学, 学術研究院医学系, 助教
2017: 信州大学, 医学部附属病院, 助教
2012: 信州大学, 医学部附属病院, 助教
Review Section/Research Field
Principal Investigator
Basic Section 53010:Gastroenterology-related / Medium-sized Section 90:Biomedical engineering and related fields / Immunology / Gastroenterology
Except Principal Investigator
Basic Section 57020:Oral pathobiological science-related / Basic Section 53010:Gastroenterology-related
Keywords
Principal Investigator
IL-33 / 原発性胆汁性肝硬変 / かゆみの可視化・定量化 / 光電式容積脈波計測法 / 皮膚掻痒症 / 脂質異常症 / PCSK9 / ウイルス学的著効 / 脂質プロファイル / 脂質変動 … More / 脂質の質的変動 / 脂質の量的変動 / プロ蛋白転換酵素サブチリシン/ケキシン9型 / 直接作用型抗ウイルス剤 / C型慢性肝炎 / 予後 / 病態 / sST2 / Autotaxin / ST2 / 原発性胆汁性胆管炎 … More
Except Principal Investigator
IgG4関連疾患 / 分子擬態 / 細菌抗原 / 遺伝子多型 / HLA / human leukocyte antigen / 肝細胞癌 / HLA class I / KIR / キラー細胞免疫グロブリン様受容体 / ヒト白血球抗原 / 肝癌 / 肝硬変 / B型慢性肝炎 Less
  • Research Projects

    (7 results)
  • Research Products

    (37 results)
  • Co-Researchers

    (11 People)
  •  免疫制御型好酸球の統合的理解と好酸球を介したアレルギー疾患の治療基盤の構築Principal Investigator

    • Principal Investigator
      城下 智
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Shinshu University
  •  Establishment of an objective evaluation method for itching and analysis of neural transmission mechanismsPrincipal Investigator

    • Principal Investigator
      城下 智
    • Project Period (FY)
      2023 – 2024
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 90:Biomedical engineering and related fields
    • Research Institution
      Shinshu University
  •  Mechanism of IgG4-related disease pathogenesis caused by molecular mimicry of bacterial antigens.

    • Principal Investigator
      吉田 明弘
    • Project Period (FY)
      2023 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 57020:Oral pathobiological science-related
    • Research Institution
      Matsumoto Dental University
  •  Interactions between lipid profile and PCSK9 changes and a role of oxidatively modified LDL on DAAs treatmentPrincipal Investigator

    • Principal Investigator
      Joshita Satoru
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Shinshu University
  •  Association analysis of KIR/HLA genotypes with HCC development in HBV

    • Principal Investigator
      Tanaka Eiji
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Shinshu University
  •  IL33/ST2 pathway involvement in the pathogenesis and disease progression of primary biliary cholangitisPrincipal Investigator

    • Principal Investigator
      JOSHITA SATORU
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Immunology
    • Research Institution
      Shinshu University
  •  次世代シーケンサーを用いた原発性胆汁性肝硬変の疾患感受性遺伝子と病態に関する研究Principal Investigator

    • Principal Investigator
      城下 智
    • Project Period (FY)
      2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Shinshu University

All 2021 2020 2019 2018 2017 2016 2012

All Journal Article Presentation

  • [Journal Article] Primary Hepatic Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue in a Patient with Chronic Hepatitis B Virus Infection: Case Report and Summary of the Literature2021

    • Author(s)
      Yamashita Yuki、Joshita Satoru、Kobayashi Hiroyuki、Wakabayashi Shun-ichi、Sugiura Ayumi、Yamazaki Tomoo、Umemura Takeji
    • Journal Title

      Medicina

      Volume: 57 Issue: 3 Pages: 280-280

    • DOI

      10.3390/medicina57030280

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08000
  • [Journal Article] Quantitative and qualitative lipid improvement with chronic hepatitis C virus eradication using with direct-acting antivirals2021

    • Author(s)
      Joshita S, Yamashita Y, Okamoto T, et al.
    • Journal Title

      Hepatology Research

      Volume: -

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07907
  • [Journal Article] Effectiveness of Glecaprevir/Pibrentasvir for Hepatitis C: Real-World Experience and Clinical Features of Retreatment Cases2020

    • Author(s)
      Sugiura Ayumi、Joshita Satoru、Yamashita Yuki、et al.
    • Journal Title

      Biomedicines

      Volume: 8 Issue: 4 Pages: 74-74

    • DOI

      10.3390/biomedicines8040074

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07907, KAKENHI-PROJECT-20K08282
  • [Journal Article] FAST score - a new predictive marker for HCC after SVR2020

    • Author(s)
      Joshita S and Umemura T
    • Journal Title

      Alimentary Pharmacology & Therapeutics

      Volume: 52 Pages: 1222-1223

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07907
  • [Journal Article] Clinical Influence of Hepatitis C Virus Eradication by Direct-acting Antivirals on Lipid Levels and “Ningen Dock” Health Check-up Categories in Patients with Chronic Hepatitis C Virus Infection2020

    • Author(s)
      Joshita Satoru、Sugiura Ayumi、Yamazaki Tomoo、et al.
    • Journal Title

      Ningen Dock International

      Volume: 7 Pages: 19-25

    • NAID

      130007868643

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07907
  • [Journal Article] Clinical impact of normal alanine aminotransferase on direct‐acting antiviral outcome in patients with chronic hepatitis C virus infection2019

    • Author(s)
      Joshita Satoru、Sugiura Ayumi、Umemura Takeji、Yamazaki Tomoo、Fujimori Naoyuki、Matsumoto Akihiro、Usami Yoko、Tanaka Eiji
    • Journal Title

      JGH Open

      Volume: - Issue: 4 Pages: 574-581

    • DOI

      10.1002/jgh3.12296

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07907
  • [Journal Article] Past history of hepatocellular carcinoma is an independent risk factor of treatment failure in patients with chronic hepatitis C virus infection receiving direct-acting antivirals2018

    • Author(s)
      Ayumi Sugiura, Satoru Joshita, Takeji Umemura, et al.
    • Journal Title

      Journal of Viral Hepatitis

      Volume: 25 Issue: 12 Pages: 1462-1471

    • DOI

      10.1111/jvh.12973

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07907, KAKENHI-PROJECT-15H01803
  • [Journal Article] Serum Autotaxin Is a Useful Disease Progression Marker in Patients with Primary Biliary Cholangitis2018

    • Author(s)
      Joshita Satoru、Umemura Takeji、Usami Yoko、Yamashita Yuki、L. Norman Gary、Sugiura Ayumi、Yamazaki Tomoo,Fujimori Naoyuki、Kimura Takefumi、Matsumoto Akihiro、Igarashi Koji、Yoshizawa Kaname、Ota Masao、Tanaka Eiji
    • Journal Title

      Scientific Reports

      Volume: 印刷中

    • NAID

      120007099792

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K21069
  • [Journal Article] Genetics and epigenetics in the pathogenesis of primary biliary cholangitis2018

    • Author(s)
      Joshita Satoru、Umemura Takeji、Tanaka Eiji、Ota Masao
    • Journal Title

      Clinical Journal of Gastroenterology

      Volume: 11 Issue: 1 Pages: 11-18

    • DOI

      10.1007/s12328-017-0799-z

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K21069, KAKENHI-PROJECT-17K09416
  • [Journal Article] Association between serum soluble CD14 and IL-8 levels and clinical outcome in primary biliary cholangitis2017

    • Author(s)
      Umemura, T. Sekiguchi, T. Joshita, S. Yamazaki, T. Fujimori, N. Shibata, S. Ichikawa, Y. Komatsu, M. Matsumoto, A. Shums, Z. Norman, G. L. Tanaka, E. Ota, M.
    • Journal Title

      Liver International

      Volume: 印刷中 Issue: 6 Pages: 897-905

    • DOI

      10.1111/liv.13316

    • NAID

      120007100137

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460996, KAKENHI-PROJECT-16K21069, KAKENHI-PROJECT-17K09416, KAKENHI-PROJECT-15H01803
  • [Journal Article] Genetic Contribution to the Pathogenesis of Primary Biliary Cholangitis.2017

    • Author(s)
      Joshita S, Umemura T, Tanaka E, Ota M.
    • Journal Title

      J Immunol Res

      Volume: 2017 Pages: 3073504-3073504

    • DOI

      10.1155/2017/3073504

    • NAID

      120007100138

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K21069, KAKENHI-PROJECT-15H01803
  • [Journal Article] Genome-wide association studies identify PRKCB as a novel genetic susceptibility locus for primary biliary cholangitis in the Japanese population.2017

    • Author(s)
      Kawashima M, Honda M, Nakamura M. et al.
    • Journal Title

      Hum Mol Genet.

      Volume: - Pages: 650-659

    • DOI

      10.1093/hmg/ddw406

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04809, KAKENHI-PROJECT-26293076, KAKENHI-PROJECT-26293181, KAKENHI-PROJECT-26460416, KAKENHI-PROJECT-26460996, KAKENHI-PROJECT-16K15426, KAKENHI-PROJECT-15K06908, KAKENHI-PROJECT-15K19314, KAKENHI-PROJECT-16K21069, KAKENHI-PROJECT-17H04058, KAKENHI-PROJECT-17H04169, KAKENHI-PROJECT-16H05283, KAKENHI-PROJECT-15K19357
  • [Journal Article] Liver stiffness-spleen size-to-platelet ratio risk score detects esophageal varices in chronic liver disease.2016

    • Author(s)
      Shibata S, Joshita S, Umemura T, Yamazaki T, Fujimori N, Ichikawa Y, Komatsu M, Matsumoto A, Tanaka E.
    • Journal Title

      Springerplus

      Volume: 5 Issue: 1 Pages: 998-998

    • DOI

      10.1186/s40064-016-2708-1

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K21069
  • [Journal Article] Genetic Association of PTPN22 Polymorphisms with Autoimmune Hepatitis and Primary Biliary Cholangitis in Japan.2016

    • Author(s)
      Umemura T, Joshita S, Yamazaki T, Komatsu M, Katsuyama Y, Yoshizawa K, Tanaka E, Ota M
    • Journal Title

      Sci Rep

      Volume: 6 Issue: 1 Pages: 29770-29770

    • DOI

      10.1038/srep29770

    • NAID

      120007100139

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H01803, KAKENHI-PROJECT-26460996, KAKENHI-PROJECT-16K21069
  • [Presentation] 実臨床における核酸アナログ等未介入例・核酸アナログ治療例・ドラックフリー例のB型肝炎の臨床的特徴と実態2020

    • Author(s)
      城下 智、松本 晶博、梅村 武司
    • Organizer
      第56回日本肝臓学会総会
    • Data Source
      KAKENHI-PROJECT-18K08000
  • [Presentation] DAA治療によるHCV排除はHDL-Cの量的変動のみならず、質的な変動にも関与する2020

    • Author(s)
      城下智、杉浦亜弓、梅村武司
    • Organizer
      第56回日本肝臓学会総会
    • Data Source
      KAKENHI-PROJECT-18K07907
  • [Presentation] 直接作用型抗ウイルス剤によるHCV排除が脂質代謝系および脂質プロファイルの量的変動と質的変動に与える影響2020

    • Author(s)
      城下智、山下裕騎、梅村武司
    • Organizer
      第43回日本肝臓学会東部会
    • Data Source
      KAKENHI-PROJECT-18K07907
  • [Presentation] ALT正常C型慢性肝炎患者に対して全例「ウイルス排除」に向けた直接作用型抗ウイルス剤治療の臨床的意義2020

    • Author(s)
      城下智、杉浦亜弓、梅村武司
    • Organizer
      第106回日本消化器病学会総会
    • Data Source
      KAKENHI-PROJECT-18K07907
  • [Presentation] 慢性肝疾患におけるATXおよびM2BPGiの非侵襲的病期診断マーカーとしての有用性とその臨床的意義2019

    • Author(s)
      城下智、梅村武司、田中榮司
    • Organizer
      第105回日本消化器病学会総会
    • Data Source
      KAKENHI-PROJECT-18K07907
  • [Presentation] Persistently Normal ALT C型慢性肝炎におけるDirect Acting Antivirals療法の臨床的特徴と実態2019

    • Author(s)
      城下智、杉浦亜弓、梅村武司
    • Organizer
      第55回日本肝臓学会総会
    • Data Source
      KAKENHI-PROJECT-18K07907
  • [Presentation] 直接作用型抗ウイルス剤治療によるC型肝炎ウイルス排除が脂質変動と脂質判定区分の変化に与える影響2019

    • Author(s)
      城下智、杉浦亜弓、梅村武司
    • Organizer
      第60回日本人間ドック学会学術大会
    • Data Source
      KAKENHI-PROJECT-18K07907
  • [Presentation] C型慢性肝炎のDAAs治療におけるLDL-Cの変化とPCSK9との関連2019

    • Author(s)
      城下智、杉浦亜弓、梅村武司
    • Organizer
      第55回日本肝癌研究会
    • Data Source
      KAKENHI-PROJECT-18K07907
  • [Presentation] C型肝炎におけるPNALT症例の特徴とDAAs治療の意義2019

    • Author(s)
      城下智、杉浦亜弓、梅村武司、田中榮司
    • Organizer
      第116回日本内科学会講演会
    • Data Source
      KAKENHI-PROJECT-18K07907
  • [Presentation] Lipoprotein-apolipoprotein changes in chronic hepatitis C patients treated with direct-acting antivirals2019

    • Author(s)
      Satoru Joshita、Ayumi Sugiura、Takeji Umemura
    • Organizer
      APASL STC 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07907
  • [Presentation] C型肝炎の直接作用型抗ウイルス剤治療における脂質の量的変動プロファイルとアポリポ蛋白変動からみた脂質の質的変動に関する検討2018

    • Author(s)
      城下智、梅村武司、田中榮司
    • Organizer
      第42回日本肝臓学会東部会
    • Data Source
      KAKENHI-PROJECT-18K07907
  • [Presentation] Clinical impact of persistently normal ALT on HCC development in HCV patients with DAA treatment2018

    • Author(s)
      Satoru Joshita, Takeji Umemura, Eiji Tanaka
    • Organizer
      APASL STC 2018 on HCC in Yokohama
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07907
  • [Presentation] C型慢性肝炎のDAAs治療におけるLDL-Cの変化とPCSK9との関連2018

    • Author(s)
      城下智、杉浦亜弓、梅村武司、沢村達也、太田正穂、田中榮司
    • Organizer
      第115回日本内科学会講演会
    • Data Source
      KAKENHI-PROJECT-18K07907
  • [Presentation] Persistently Normal ALT C型慢性肝炎におけるDirect Acting Antivirals療法の臨床的特徴と実態2018

    • Author(s)
      城下智、梅村武司、田中榮司
    • Organizer
      第54回日本肝臓学会総会
    • Data Source
      KAKENHI-PROJECT-18K07907
  • [Presentation] Asymptomatic and symptomatic states are independent risk factors predicting PBC long-term outcome2017

    • Author(s)
      Joshita Satoru、Umemura Takeji、Tanaka Eiji
    • Organizer
      The Asian Pacific Association for the Study of the Liver Single Topic Conference 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K21069
  • [Presentation] Association of Serum Autotaxin Level with Disease Stage in Japanese Patients with Primary Biliary Cholangitis2017

    • Author(s)
      Joshita Satoru、Umemura Takeji、Yoko Usami、Sugiura Ayumi、Yamazaki Tomoo、Fujimori Naoyuki、Komatsu Michiharu、Matsumoto Akihiro、Igarashi Koji、Ota Masao、Tanaka Eiji
    • Organizer
      The Asian Pacific Digestive week 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K21069
  • [Presentation] IL33/ST2 pathway involvement in the pathogenesis and disease progression of primary biliary cholangitis2017

    • Author(s)
      Joshita Satoru、Umemura Takeji、Matsumoto Akihiro、Yoshizawa Kaname、Ota Masao、Tanaka Eiji
    • Organizer
      Digestive Disease Week 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K21069
  • [Presentation] 原発性胆汁性胆管炎における血中Autotaxinの臨床的意義の検討2017

    • Author(s)
      城下智、梅村武司、田中榮司
    • Organizer
      第25回日本消化器関連学会週間
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K21069
  • [Presentation] Liver Stiffness-Spleen Size-to-Platelet Ratio Risk Score Identifies Esophageal Varices in Chronic Liver Disease2016

    • Author(s)
      Joshita S, Shibata S, Umemura T, Sugiura A, Yamazaki S, Fujimori N, Ichikawa Y, Komatsu M, Matsumoto A, Tanaka E.
    • Organizer
      HCV 2016 23rd International Symposium on Hepatitis C Virus and Related Viruses (国際学会)
    • Place of Presentation
      Kyoto, Kyoto International Conference Center
    • Year and Date
      2016-10-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K21069
  • [Presentation] 原発性胆汁性胆管炎の線維化進行と病態進展におけるIL-33/ST2 pathwayの役割2016

    • Author(s)
      城下 智、梅村 武司、田中 榮司
    • Organizer
      第41回日本肝臓学会東部会
    • Place of Presentation
      東京、京王プラザホテル
    • Year and Date
      2016-12-08
    • Data Source
      KAKENHI-PROJECT-16K21069
  • [Presentation] 無症候性および症候性原発性胆汁性肝硬変の予後解析2016

    • Author(s)
      城下 智、梅村 武司、吉澤 要、田中 榮司
    • Organizer
      第113回日本内科学会講演会
    • Place of Presentation
      東京、東京国際フォーラム
    • Year and Date
      2016-04-15
    • Data Source
      KAKENHI-PROJECT-16K21069
  • [Presentation] PTPN22遺伝子多型は自己免疫性肝疾患の疾患抵抗性と関連する2016

    • Author(s)
      城下智、梅村武司、山崎智生、齊藤博美、平山敦大、赤羽由紀、山崎麻美、田中栄司、勝山善彦、太田正穂
    • Organizer
      第25回日本組織適合性学会大会
    • Place of Presentation
      札幌、北海道大学学術交流会館
    • Year and Date
      2016-10-22
    • Data Source
      KAKENHI-PROJECT-16K21069
  • [Presentation] Signal Transducer and Activator of Transcription 4 遺伝子多型と日本人の原発性胆汁性肝硬変発症に関する検討2012

    • Author(s)
      城下智
    • Organizer
      第48回日本肝臓学会総会
    • Place of Presentation
      金沢
    • Year and Date
      2012-06-07
    • Data Source
      KAKENHI-PROJECT-24790688
  • 1.  太田 正穂 (50115333)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 2.  Tanaka Eiji (50163506)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 3.  沢村 達也 (30243033)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 4.  阿部 誠 (90604637)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  川田 一仁 (90722968)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  吉田 明弘 (20364151)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  川 茂幸 (10177628)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  宇田川 信之 (70245801)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  堀部 寛治 (70733509)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  梅村 武司
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  本多 政夫
    # of Collaborated Projects: 0 results
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