Sato Naoya 佐藤直哉

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SATO Naoya 佐藤直哉

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Researcher Number	90622332
Other IDs
Affiliation (Current)	2025: 福島県立医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2021 – 2024: 福島県立医科大学, 医学部, 助教 2020: 福島県立医科大学, 医学部, 博士研究員 2015 – 2019: 福島県立医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 55010:General surgery and pediatric surgery-related / General surgery / Digestive surgery Except Principal Investigator Basic Section 55020:Digestive surgery-related
Keywords	Principal Investigator 膵島移植 / Mitomycin-C / 組織再生 / 免疫寛容 / 膵島細胞シート / 皮下移植 / innate immune response / immune tolerance / islet transplantation / 自然免疫 … More / 樹状細胞 / 前処置 / Mitomysin-C / preconditioning / Mitomyciｎ-C / 免疫原性低下 / サイトカイン / マイクロアレイ / 免疫抑制 / 生着延長 … More Except Principal Investigator 肝細胞スフェロイド / 3D培養 / 肝再生 / ３次元骨格 / 細胞間接着 / 肝組織由来スフェロイド / 皮下移植 / リコンビナントペプチド / 細胞シート / スフェロイド / シート技術 / 肝細胞分離 / 肝組織 / ３D培養 / 複合型肝細胞シート / 肝スフェロイド / 肝細胞 Less

Application of composite cell sheets of adipose-derived mesenchymal stem cells and pancreatic islet cells for expansion of donor sourcesPrincipal Investigator
- Principal Investigator
  
  佐藤直哉
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Fukushima Medical University
肝組織由来スフェロイドを用いた肝オルガノイドの開発とその微小環境分子機構の解明
- Principal Investigator
  
  丸橋繁
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Fukushima Medical University
Regulation of innate immune response and induction donor specific immune tolerance by Ex-vivo pretreatment of islets with Mitomycin-CPrincipal Investigator
- Principal Investigator
  
  佐藤直哉
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Fukushima Medical University
Research on the Development of Composite Hepatocyte Sheets Using Liver Tissue-Derived Spheroids (LTOSs)
- Principal Investigator
  
  MARUBASHI Shigeru
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Fukushima Medical University
Ex-vivo pretreatment of islets with Mitomycin-C have a potential to induce specific immune response for peripheral tolerancePrincipal Investigator
- Principal Investigator
  
  Sato Naoya
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General surgery
- Research Institution
  Fukushima Medical University
Ex-vivo Mitomycin-C pretreatment induced lower immunogenic potential of islets via suppressing secretion of multiple chemotaxis factors.Principal Investigator
- Principal Investigator
  
  SATO Naoya
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Fukushima Medical University

All 2023 2022 2021 2018 2017 2016 2015

All Journal Article Presentation Book

[Book] 臨床膵島移植の現状.2015
- Author(s)
  佐藤直哉, 穴澤貴行, 後藤満一
- Total Pages
  6
- Publisher
  医学出版
- Data Source
  KAKENHI-PROJECT-15K19902
[Journal Article] Induction of Immune Tolerance in Islet Transplantation Using Apoptotic Donor Leukocytes.2021
- Author(s)
  5)Sato N, Marubashi S
- Journal Title
  
  J Clin Med
  
  Volume: 10 Issue: 22 Pages: 5306-5306
- DOI
  10.3390/jcm10225306
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08624
[Journal Article] Ex vivo Pretreatment of Islets with Mitomycin C2017
- Author(s)
  Sato Naoya、Haga Junichiro、Anazawa Takayuki、Kenjo Akira、Kimura Takashi、Wada Ikuo、Mori Tsutomu、Marubashi Shigeru、Gotoh Mitsukazu
- Journal Title
  
  Cell Transplantation
  
  Volume: 26 Issue: 8 Pages: 1392-1404
- DOI
  10.1177/0963689717721233
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16512, KAKENHI-PROJECT-15K10033, KAKENHI-PROJECT-17K19687
[Journal Article] Mitomycin-C処置によるグラフト生着延長効果2016
- Author(s)
  佐藤直哉、　穴澤貴行、　後藤満一
- Journal Title
  
  Organ Biology
  
  Volume: 22 Pages: 117-122
- Data Source
  KAKENHI-PROJECT-15K19902
[Presentation] ADSC‐膵島複合細胞シートの門脈外異所性移植の可能性‐皮下移植と腹腔内移植の比較－2023
- Author(s)
  佐藤直哉
- Organizer
  膵・膵島移植学会
- Data Source
  KAKENHI-PROJECT-21K08624
[Presentation] 脂肪由来幹細胞(ADSC)を付加は、膵島細胞シートの移植効率を改善する2022
- Author(s)
  佐藤直哉
- Organizer
  移植学会
- Data Source
  KAKENHI-PROJECT-21K08624
[Presentation] Ex-vivo pretreatment of islets with Mitomycin-C have a potential to induce specific immune response for peripheral tolerance.2018
- Author(s)
  Naoya Sato, Akira Kenjo, Takashi Kimura, Ryo Okada, Terushige Ishigame, Yasuhide Kofunato, Junichiro Watanabe, Makoto Muto, Seiko Suzushino, Shigeru Marubashi
- Organizer
  American transplant congress 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16512
[Presentation] 移植前Mitomycin-C処置に対する末梢性免疫寛容性免疫応答の検討2018
- Author(s)
  佐藤直哉　岡田良　石亀輝英　小船戸康英　渡邊淳一郎　武藤亮　鈴志野聖子　月田茂之　木村隆　見城明　志村龍男　丸橋繁
- Organizer
  日本移植学会
- Data Source
  KAKENHI-PROJECT-17K16512
[Presentation] Ex-Vivo Pretreatment of Islets with Mitomycin-C Have a Potential to Induce Specific Immune Response for Peripheral Tolerance2018
- Author(s)
  Naoya Sato, Akira Kenjo, Takashi Kimura, Ryo Okada, Terushige Ishigame, Yasuhide Kofunato, Junichiro Watanabe, Makoto Muto, Seiko Suzushino, Shigeru Marubashi
- Organizer
  American Transplant Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16512
[Presentation] 分離膵島のMitomycin-C前処置による生着延長メカニズム -複数の免疫細胞遊走因子の分泌抑制がもたらす局所免疫不応答-2016
- Author(s)
  佐藤直哉、芳賀淳一郎、穴澤貴行、見城　明、丸橋　繁、木村　隆、渡邊淳一郎、後藤満一
- Organizer
  第116回日本外科学会定期学術集会
- Place of Presentation
  大阪国際会議場（大阪府大阪市）
- Year and Date
  2016-04-14
- Data Source
  KAKENHI-PROJECT-15K19902
[Presentation] Mitomycin-C処置による膵島サイトカイン分泌抑制に関与する上流制御因子の解明2016
- Author(s)
  佐藤直哉、見城明、丸橋繁、木村隆、渡邊淳一郎、武藤亮、西間木淳
- Organizer
  第52回日本移植学会総会
- Place of Presentation
  グランドプリンスホテル新高輪国際館パミール（東京都港区）
- Year and Date
  2016-09-29
- Data Source
  KAKENHI-PROJECT-15K19902
[Presentation] Mitomycin-C処置膵島の遺伝子プロファイルの解析;生着延長における複数の免疫細胞遊走因子抑制の可能性2016
- Author(s)
  佐藤直哉, 芳賀淳一郎, 穴澤貴行, 見城　明, 丸橋　繁, 木村　隆, 渡邊淳一郎
- Organizer
  第71回日本消化器外科学会総会
- Place of Presentation
  アスティとくしま（徳島県徳島市）
- Year and Date
  2016-07-14
- Data Source
  KAKENHI-PROJECT-15K19902
[Presentation] Inhibition of cytokine secretion from islets by ex-vivo Mitomycin-c treatment2015
- Author(s)
  佐藤直哉, 芳賀淳一郎, 穴澤貴行, 見城　明, 丸橋　繁, 木村　隆, 佐藤　哲, 渡邊淳一郎, 菊池智弘, 後藤満一
- Organizer
  第70回日本消化器外科学会総会
- Place of Presentation
  浜松
- Year and Date
  2015-07-15
- Data Source
  KAKENHI-PROJECT-15K19902
[Presentation] Comprehensive gene analysis on ex-vivo Mitomycin-C treatment as a potential protocol for inducing unresponsiveness to islet engraftment -harmonised suppression of multiple chemotaxis factors2015
- Author(s)
  Sato N, Anazawa T, Haga J, Kenjo A, Marubashi S, Kimura T, (Wada I, Mori T), Gotoh M
- Organizer
  IPITA-IXA-CTS 2015 Joint Congress
- Place of Presentation
  Melbourne, Australia
- Year and Date
  2015-11-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19902

1. 清水裕史 (70553709)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. MARUBASHI Shigeru (20362725)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 石亀輝英 (50583358)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 見城明 (40305355)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 武藤亮 (10791478)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 鈴志野聖子 (20816376)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 小船戸康英 (70583425)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Sato Naoya 佐藤 直哉

SATO Naoya 佐藤 直哉

Research Projects

Research Products

Co-Researchers

Application of composite cell sheets of adipose-derived mesenchymal stem cells and pancreatic islet cells for expansion of donor sourcesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

肝組織由来スフェロイドを用いた肝オルガノイドの開発とその微小環境分子機構の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulation of innate immune response and induction donor specific immune tolerance by Ex-vivo pretreatment of islets with Mitomycin-CPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Research on the Development of Composite Hepatocyte Sheets Using Liver Tissue-Derived Spheroids (LTOSs)

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Ex-vivo pretreatment of islets with Mitomycin-C have a potential to induce specific immune response for peripheral tolerancePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Ex-vivo Mitomycin-C pretreatment induced lower immunogenic potential of islets via suppressing secretion of multiple chemotaxis factors.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 臨床膵島移植の現状.2015

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Induction of Immune Tolerance in Islet Transplantation Using Apoptotic Donor Leukocytes.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ex vivo Pretreatment of Islets with Mitomycin C2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mitomycin-C処置によるグラフト生着延長効果2016

Author(s)

Journal Title

Data Source

[Presentation] ADSC‐膵島複合細胞シートの門脈外異所性移植の可能性‐皮下移植と腹腔内移植の比較－2023

Author(s)

Organizer

Data Source

[Presentation] 脂肪由来幹細胞(ADSC)を付加は、膵島細胞シートの移植効率を改善する2022

Author(s)

Organizer

Data Source

[Presentation] Ex-vivo pretreatment of islets with Mitomycin-C have a potential to induce specific immune response for peripheral tolerance.2018

Author(s)

Organizer

Data Source

[Presentation] 移植前Mitomycin-C処置に対する末梢性免疫寛容性免疫応答の検討2018

Author(s)

Organizer

Data Source

[Presentation] Ex-Vivo Pretreatment of Islets with Mitomycin-C Have a Potential to Induce Specific Immune Response for Peripheral Tolerance2018

Author(s)

Organizer

Data Source

Sato Naoya 佐藤直哉

SATO Naoya 佐藤直哉

[Presentation] 分離膵島のMitomycin-C前処置による生着延長メカニズム -複数の免疫細胞遊走因子の分泌抑制がもたらす局所免疫不応答-2016