SATO YOSHIFUMI 佐藤叔史

… Alternative Names

SATO Yoshifumi 佐藤叔史

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Researcher Number	90622598
Other IDs
Affiliation (Current)	2025: 熊本大学, 大学院生命科学研究部(医), 助教
Affiliation (based on the past Project Information) *help	2012 – 2025: 熊本大学, 大学院生命科学研究部(医), 助教 2013 – 2015: 熊本大学, 大学院生命科学研究部, 助教
Review Section/Research Field	Principal Investigator Basic Section 54040:Metabolism and endocrinology-related / Metabolomics Except Principal Investigator Basic Section 54040:Metabolism and endocrinology-related / Metabolomics / Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
Keywords	Principal Investigator 糖尿病 / 膵β細胞 / 低酸素 / β細胞代償機構 / β細胞 / 転写因子 / インクレチン / 酸素 / 膵α細胞 / 肝臓 / インスリン分泌 … More Except Principal Investigator … More サーチュイン / 糖尿病 / 褐色脂肪細胞 / SIRT7 / 褐色脂肪組織 / 脂肪細胞 / インスリン / インスリン分泌 / 糖代謝 / シングルセル解析 / エピゲノム / β細胞 / 老化 / FGF21 / 寿命 / IMP2 / 糖新生 / 炎症 / エネルギー代謝 / サーチュン / DDB1 / 褐色脂肪 / ユビキチンリガーゼ複合体 / TR4 / 肝臓 / ＳＩＲＴ７ / 脂肪肝 / グルコキナーゼ / HNF / MODY / 転写因子 Less

サーチュイン7（SIRT7）による糖代謝制御の統合的理解とその制御法の開発
- Principal Investigator
  
  山縣和也
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Kumamoto University
Elucidation of the Incretin-Mediated Mechanism for Suppression of Hypoxia in Pancreatic beta-CellsPrincipal Investigator
- Principal Investigator
  
  佐藤叔史
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Kumamoto University
Elucidation of molecular mechanism of age-associated impaired insulin secretion by single cell analysis
- Principal Investigator
  
  山縣和也
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  Kumamoto University
The role of ANKS4B in glucose metabolismPrincipal Investigator
- Principal Investigator
  
  佐藤叔史
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Kumamoto University
Regulation of glucose metabolism by SIRT7
- Principal Investigator
  
  山縣和也
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Kumamoto University
Beta-cell decompensation by chronic hypoxiaPrincipal Investigator
- Principal Investigator
  
  SATO YOSHIFUMI
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Kumamoto University
Identification of the metabolic roles of SIRT7 and the development of its regulation.
- Principal Investigator
  
  Yamagata Kazuya
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Kumamoto University
Pathophysiological role of pancreatic beta-cell hypoxiaPrincipal Investigator
- Principal Investigator
  
  SATO YOSHIFUMI
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Kumamoto University
Identification of the multifaceted metabolic roles of SIRT7
- Principal Investigator
  
  Yamagata Kazuya
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  Kumamoto University
The pathophysiological role of pancreatic beta-cell hypoxia in the progression of diabetesPrincipal Investigator
- Principal Investigator
  
  SATO Yoshifumi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  Kumamoto University
Molecular mechanism of diabetes mellitus based on beta-cell transcription factor network
- Principal Investigator
  
  Yamagata Kazuya
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  Kumamoto University
Proteasomal regulation of HNF4 alpha protein by hypoxia in pancreatic beta-cells.Principal Investigator
- Principal Investigator
  
  SATO Yoshifumi
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  Kumamoto University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 Other

All Journal Article Presentation Book

[Book] 内分泌・糖尿病・代謝内科352012
- Author(s)
  佐藤叔史, 山縣和也, 井上正宏
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-24790932
[Book] 内分泌・糖尿病・代謝内科2012
- Author(s)
  佐藤叔史
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-24790932
[Book] 実験医学増刊2012
- Author(s)
  佐藤叔史
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-24790932
[Book] 実験医学増刊活性酸素・ガス状分子による恒常性制御と疾患監修 : 山本雅之, 膵β細胞における低酸素応答と糖代謝異常2012
- Author(s)
  佐藤叔史, 山縣和也
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-24790932
[Journal Article] Roles of β-Cell Hypoxia in the Progression of Type 2 Diabetes2024
- Author(s)
  Yamagata Kazuya、Tsuyama Tomonori、Sato Yoshifumi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 25 Issue: 8 Pages: 4186-4186
- DOI
  10.3390/ijms25084186
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K18302, KAKENHI-PROJECT-23K24388
[Journal Article] Hypoxia causes pancreatic β‐cell dysfunction and impairs insulin secretion by activating the transcriptional repressor BHLHE402023
- Author(s)
  Tsuyama Tomonori、Sato Yoshifumi、Yoshizawa Tatsuya、Matsuoka Takaaki、Yamagata Kazuya
- Journal Title
  
  EMBO reports
  
  Volume: 24 Issue: 8
- DOI
  10.15252/embr.202256227
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18302, KAKENHI-PROJECT-22K08658, KAKENHI-PROJECT-22K16399, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-23K24388
[Journal Article] Phosphatase protector alpha4 (α4) is involved in adipocyte maintenance and mitochondrial homeostasis through regulation of insulin signaling2022
- Author(s)
  Sakaguchi Masaji、Okagawa Shota、Okubo Yuma、Otsuka Yuri、Fukuda Kazuki、Igata Motoyuki、Kondo Tatsuya、Sato Yoshifumi、Yoshizawa Tatsuya、Fukuda Takaichi、Yamagata Kazuya、Cai Weikang、Tseng Yu-Hua、Sakaguchi Nobuo、Kahn C. Ronald、Araki Eiichi
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 6092-6092
- DOI
  10.1038/s41467-022-33842-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08533, KAKENHI-PROJECT-22K08658, KAKENHI-PROJECT-22H04922
[Journal Article] SIRT7 Deficiency Protects against Aβ(42)-Induced Apoptosis through the Regulation of NOX4-Derived Reactive Oxygen Species Production in SH-SY5Y Cells2022
- Author(s)
  Mizutani H, Sato Y, Yamazaki M, Yoshizawa T, Ando Y, Ueda M, Yamagata K.
- Journal Title
  
  Int J Mol Sci
  
  Volume: 23 Issue: 16 Pages: 9027-9027
- DOI
  10.3390/ijms23169027
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07528, KAKENHI-PROJECT-22K08658, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-23K24388
[Journal Article] SIRT7 suppresses energy expenditure and thermogenesis by regulating brown adipose tissue functions in mice2022
- Author(s)
  Yoshizawa Tatsuya、Sato Yoshifumi、Sobuz Shihab U.、Mizumoto Tomoya、Tsuyama Tomonori、Karim Md. Fazlul、Miyata Keishi、Tasaki Masayoshi、Yamazaki Masaya、Kariba Yuichi、Araki Norie、Araki Eiichi、Kajimura Shingo、Oike Yuichi、Braun Thomas、Bober Eva、Auwerx Johan、Yamagata Kazuya
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 7439-7439
- DOI
  10.1038/s41467-022-35219-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08533, KAKENHI-PROJECT-22K08187, KAKENHI-PROJECT-22K08658, KAKENHI-PROJECT-22K19533, KAKENHI-PROJECT-22K16399, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-20H04107, KAKENHI-PROJECT-23K24388, KAKENHI-PROJECT-19H03772, KAKENHI-PROJECT-22F22111
[Journal Article] SIRT7 Deficiency Protects against Aging-Associated Glucose Intolerance and Extends Lifespan in Male Mice2022
- Author(s)
  Mizumoto Tomoya、Yoshizawa Tatsuya、Sato Yoshifumi、Ito Takaaki、Tsuyama Tomonori、Satoh Akiko、Araki Satoshi、Tsujita Kenichi、Tamura Masaru、Oike Yuichi、Yamagata Kazuya
- Journal Title
  
  Cells
  
  Volume: 11 Issue: 22 Pages: 3609-3609
- DOI
  10.3390/cells11223609
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08658, KAKENHI-PROJECT-22K19533, KAKENHI-PROJECT-22K16399, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-20H04107, KAKENHI-PROJECT-23K24388, KAKENHI-PROJECT-23K24805
[Journal Article] Development of a DELFIA method to detect oncofetal antigen ROR1-positive exosomes2021
- Author(s)
  Daikuzono Hina、Yamazaki Masaya、Sato Yoshifumi、Takahashi Takashi、Yamagata Kazuya
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 578 Pages: 170-176
- DOI
  10.1016/j.bbrc.2021.08.054
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09008, KAKENHI-PROJECT-19H03711, KAKENHI-PROJECT-16H06276
[Journal Article] HNF1α controls glucagon secretion in pancreatic α-cells through modulation of SGLT12020
- Author(s)
  Sato Yoshifumi、Rahman Md Mostafizur、Haneda Masaki、Tsuyama Tomonori、Mizumoto Tomoya、Yoshizawa Tatsuya、Kitamura Tadahiro、Gonzalez Frank J.、Yamamura Ken-ichi、Yamagata Kazuya
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  
  Volume: 1866 Issue: 11 Pages: 165898-165898
- DOI
  10.1016/j.bbadis.2020.165898
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09008, KAKENHI-PROJECT-20K17538, KAKENHI-PROJECT-19H03711, KAKENHI-PROJECT-19K22639, KAKENHI-PROJECT-16H06276
[Journal Article] Brown adipocyte-derived exosomal miR-132-3p suppress hepatic Srebf1 expression and thereby attenuate expression of lipogenic genes2020
- Author(s)
  Kariba Yuichi、Yoshizawa Tatsuya、Sato Yoshifumi、Tsuyama Tomonori、Araki Eiichi、Yamagata Kazuya
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 530 Issue: 3 Pages: 500-507
- DOI
  10.1016/j.bbrc.2020.05.090
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09008, KAKENHI-PROJECT-20K17538, KAKENHI-PROJECT-19H03711, KAKENHI-PROJECT-18K08482, KAKENHI-PROJECT-19K22639, KAKENHI-PROJECT-16H06276
[Journal Article] SIRT7 regulates the nuclear export of NF-κB p65 by deacetylating Ran2019
- Author(s)
  Sobuz Shihab U.、Sato Yoshifumi、Yoshizawa Tatsuya、Karim Fazlul、Ono Katsuhiko、Sawa Tomohiro、Miyamoto Yoichi、Oka Masahiro、Yamagata Kazuya
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  
  Volume: 1866 Issue: 9 Pages: 1355-1367
- DOI
  10.1016/j.bbamcr.2019.05.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09008, KAKENHI-PROJECT-19K22639, KAKENHI-PROJECT-17H03679, KAKENHI-PROJECT-19H03711, KAKENHI-PROJECT-16H06276
[Journal Article] SIRT7 has a critical role in bone formation by regulating lysine acylation of SP7/Osterix2018
- Author(s)
  Fukuda Masatoshi、Yoshizawa Tatsuya et al.
- Journal Title
  
  Nature Communications
  
  Volume: 9 Issue: 1 Pages: 2833-2833
- DOI
  10.1038/s41467-018-05187-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06600, KAKENHI-PUBLICLY-17H05650, KAKENHI-PROJECT-16H05328, KAKENHI-PROJECT-17H04105, KAKENHI-PROJECT-15K11027, KAKENHI-PROJECT-16K09758, KAKENHI-PROJECT-17K11014, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H05440
[Journal Article] Sirtuin 7 Deficiency Ameliorates Cisplatin-induced Acute Kidney Injury Through Regulation of the Inflammatory Response2018
- Author(s)
  Miyasato Yoshikazu、Yoshizawa Tatsuya、Sato Yoshifumi、Nakagawa Terumasa、Miyasato Yuko、Kakizoe Yutaka、Kuwabara Takashige、Adachi Masataka、Ianni Alessandro、Braun Thomas、Komohara Yoshihiro、Mukoyama Masashi、Yamagata Kazuya
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 5927-5927
- DOI
  10.1038/s41598-018-24257-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09268, KAKENHI-PROJECT-26461234, KAKENHI-PROJECT-17K09705, KAKENHI-PROJECT-17K09706, KAKENHI-PROJECT-16H05328, KAKENHI-PROJECT-16K09758, KAKENHI-PROJECT-16H06276
[Journal Article] SIRT7 is an important regulator of cartilage homeostasis and osteoarthritis development.2018
- Author(s)
  Korogi W, Yoshizawa T, Karim MF, Tanoue H, Yugami M, Sobuz SU, Hinoi E, Sato Y, Oike Y, Mizuta H, Yamagata K
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 印刷中 Issue: 3 Pages: 891-897
- DOI
  10.1016/j.bbrc.2018.01.129
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05328, KAKENHI-PROJECT-16K09758
[Journal Article] SIRT7-dependent deacetylation of DDB1 regulates the expression of nuclear receptor TR42017
- Author(s)
  Karim MF, Yoshizawa T, Sobuz SU, Sato Y, Yamagata K
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 490 Issue: 2 Pages: 423-428
- DOI
  10.1016/j.bbrc.2017.06.057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05328
[Journal Article] Hypoxia reduces HNF4alpha/MODY1 protein expression in pancreatic beta-cells by activating AMP-activated protein kinase.2017
- Author(s)
  Sato Y, Karim MF et al.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 印刷中 Issue: 21 Pages: 8716-8728
- DOI
  10.1074/jbc.m116.767574
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K21238, KAKENHI-PROJECT-16K09758, KAKENHI-PROJECT-16H05328
[Journal Article] Volatile anesthetics suppress glucose-stimulated insulin secretion in MIN6 cells by inhibiting glucose-induced activation of hypoxia-inducible factor 1.2015
- Author(s)
  Suzuki K, Sato Y, Kai S, Nishi K, Adachi T, Matsuo Y, Hirota K.
- Journal Title
  
  PeerJ.
  
  Volume: 3 Pages: 1498-1498
- DOI
  10.7717/peerj.1498
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10551, KAKENHI-PROJECT-15K20063, KAKENHI-PROJECT-26670693, KAKENHI-PROJECT-26860697
[Journal Article] Roles of hepatic glucokinase in intertissue metabolic communication: Examination of novel liver-specific glucokinase knockout mice.2015
- Author(s)
  Hayashi H, Sato Y, Li Z, Yamamura KI, Yoshizawa T, Yamagata K.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: In press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26860697
[Journal Article] Role of SIRT7 in hepatic lipid metabolism.2015
- Author(s)
  Yamagata K, Karim MF, Sato Y, Yoshizawa T.
- Journal Title
  
  Diabetology International
  
  Volume: 6 Pages: 193-196
- NAID
  40020601082
- Data Source
  KAKENHI-PROJECT-26860697
[Journal Article] High resolution imaging of intracellular oxygen concentration by phosphorescence lifetime2015
- Author(s)
  Kurokawa H, Ito H, Inoue M, Tabata K, Sato Y, Yamagata K, Kizaka-Kondoh S, Kadonosono T, Yano S, Kamachi T.
- Journal Title
  
  Sci Rep.
  
  Volume: 5 Issue: 1 Pages: 10657-10657
- DOI
  10.1038/srep10657
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-26111005, KAKENHI-PROJECT-25250012, KAKENHI-PROJECT-15H03003, KAKENHI-PROJECT-26860697, KAKENHI-PROJECT-25288028, KAKENHI-PROJECT-25293212
[Journal Article] Moderate hypoxia induces beta-cell dysfunction with HIF-1alpha independent gene expression changes2014
- Author(s)
  Sato Y
- Journal Title
  
  PLOS ONE
  
  Volume: 9 Issue: 12 Pages: e114868-e114868
- DOI
  10.1371/journal.pone.0114868
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25293212, KAKENHI-ORGANIZER-26111001, KAKENHI-PROJECT-26860697
[Journal Article] SIRT7 controls hepatic lipid metabolism by regulating the ubiquitin-proteasome pathway.2014
- Author(s)
  Yoshizawa T, Karim Md. F, Sato Y, Senokuchi T, Miyata K, Fukuda T, Go C, Tasaki M, Uchimura K, Kadomatsu T, Tian Z, Smolka C, Sawa T, Kakeya M, Tomizawa K, Ando Y, Araki E, Akaike T, Braun T, Oike Y, Bober E, Yamagata K.
- Journal Title
  
  Cell Metab.
  
  Volume: 9 Issue: 4 Pages: 712-721
- DOI
  10.1016/j.cmet.2014.03.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-11F01105, KAKENHI-ORGANIZER-20117001, KAKENHI-PLANNED-20117005, KAKENHI-PROJECT-21220010, KAKENHI-PROJECT-24390082, KAKENHI-PROJECT-24790557, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-25253020, KAKENHI-PROJECT-25293212, KAKENHI-PROJECT-25461114, KAKENHI-PROJECT-25461361, KAKENHI-PROJECT-25870543, KAKENHI-PLANNED-26111008, KAKENHI-PUBLICLY-26116722, KAKENHI-PROJECT-26293190, KAKENHI-PROJECT-26670207, KAKENHI-PROJECT-26670405, KAKENHI-PROJECT-26860697, KAKENHI-PROJECT-26861112
[Journal Article] Interferon stimulated gene 15 has an anti-apoptotic effect on MIN6 cells2014
- Author(s)
  Yoshikawa A, Imagawa A, Nakata S, Fukui K, Kuroda Y, Miyata Y, Sato Y, Hanafusa T, Matsuoka TA, Kaneto H, Iwahashi H, Shimomura I.
- Journal Title
  
  Endocr J
  
  Volume: 61 Issue: 9 Pages: 883-890
- DOI
  10.1507/endocrj.EJ14-0219
- NAID
  130004443987
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24591362, KAKENHI-PROJECT-26860697
[Journal Article] Low serum level of high-sensitivity C-reactive protein in a Japanese subject with MODY3.2014
- Author(s)
  Ohki T, Utsu Y, Morita S, Karim MF, Sato Y, Yoshizawa T, Yamamura K, Yamada K, Kasayama S, Yamagata K.
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: in press Issue: 5 Pages: 513-516
- DOI
  10.1111/jdi.12237
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790932, KAKENHI-PROJECT-26860697, KAKENHI-PROJECT-221S0001
[Journal Article] Inhibition of H3K18 deacetylation of SIRT7 by Myb-binding protein la (Mybbpla)2013
- Author(s)
  Karim Md F, Yoshizawa T, Sato Y, Sawa T, Tomizawa K, A kaike T and Yamagata K.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 441 Issue: 1 Pages: 157-163
- DOI
  10.1016/j.bbrc.2013.10.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11F01105, KAKENHI-ORGANIZER-20117001, KAKENHI-PLANNED-20117005, KAKENHI-PROJECT-21220010, KAKENHI-PROJECT-24390082, KAKENHI-PROJECT-24790932, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-25253020, KAKENHI-PROJECT-25293212
[Journal Article] Identification of hepatocyte growth factor activator (Hgfac) gene as a target of HNF1α in mouse β-cells2012
- Author(s)
  Ohki T, Sato Y, Yoshizawa T, Yamamura K, Yamada K, Yamagata K
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 425 Issue: 3 Pages: 619-624
- DOI
  10.1016/j.bbrc.2012.07.134
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21220010, KAKENHI-PROJECT-24790932, KAKENHI-PROJECT-221S0001, KAKENHI-PUBLICLY-23126521
[Journal Article] Anks4b, a novel target of HNF4α interacts with GRP78 and regulates endoplasmic reticulum stress-induced apoptosis in pancreatic β-cells2012
- Author(s)
  Sato Y, Hatta M, Karim MF, Sawa T, Wei F-Y, Sato S, Magnuson MA, Gonzalez FJ, Tomizawa K, Akaike T, Yoshizawa T, and Yamagata K
- Journal Title
  
  J. Biol. Chem
  
  Volume: 287 Issue: 27 Pages: 23236-23245
- DOI
  10.1074/jbc.m112.368779
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117005, KAKENHI-PROJECT-21220010, KAKENHI-PROJECT-24790932, KAKENHI-ORGANIZER-20117001, KAKENHI-PUBLICLY-23126521
[Presentation] 低酸素誘導性インスリン分泌不全の分子機構の解明2023
- Author(s)
  津山友徳、佐藤叔史、松岡孝昭、山縣和也
- Organizer
  第６１回日本糖尿病学会九州地方会
- Data Source
  KAKENHI-PROJECT-23K18302
[Presentation] 脱アセチル化酵素SIRT7による肝糖新生制御機構の解明2023
- Author(s)
  水本智也、佐藤叔史、津山友徳、山縣和也
- Organizer
  第６１回日本糖尿病学会九州地方会
- Data Source
  KAKENHI-PROJECT-23K18302
[Presentation] 膵β細胞における低酸素誘導性ATF3の役割2023
- Author(s)
  佐藤叔史 , 津山友徳 , 山縣和也
- Organizer
  第61回日本糖尿病学会九州地方会
- Data Source
  KAKENHI-PROJECT-22K08658
[Presentation] 膵β細胞における低酸素誘導因子ATF3の役割2023
- Author(s)
  佐藤叔史、津山友徳、山縣和也
- Organizer
  第６１回日本糖尿病学会九州地方会
- Data Source
  KAKENHI-PROJECT-23K24388
[Presentation] 脱アセチル化酵素SIRT7による肝糖新生制御機構の解明2023
- Author(s)
  水本智也、佐藤叔史、津山友徳、山縣和也
- Organizer
  第６１回日本糖尿病学会九州地方会
- Data Source
  KAKENHI-PROJECT-23K24388
[Presentation] 膵β細胞における低酸素誘導因子ATF3の役割2023
- Author(s)
  佐藤叔史、津山友徳、山縣和也
- Organizer
  第６１回日本糖尿病学会九州地方会
- Data Source
  KAKENHI-PROJECT-23K18302
[Presentation] 低酸素誘導性インスリン分泌不全の分子機構の解明2023
- Author(s)
  津山友徳、佐藤叔史、松岡孝昭、山縣和也
- Organizer
  第６１回日本糖尿病学会九州地方会
- Data Source
  KAKENHI-PROJECT-23K24388
[Presentation] プロインスリンと膵β細胞老化2022
- Author(s)
  佐藤叔史
- Organizer
  第65 回日本糖尿病学会年次学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-22K08658
[Presentation] 転写因子HNF1αによる膵α細胞制御機構の解明2021
- Author(s)
  佐藤叔史
- Organizer
  第59回日本糖尿病学会九州地方会(九州支部賞受賞講演）
- Invited
- Data Source
  KAKENHI-PROJECT-19K09008
[Presentation] 低酸素誘導性の転写抑制因子BHLHE40による膵β細胞障害機構2021
- Author(s)
  佐藤叔史
- Organizer
  第64 回日本糖尿病学会年次学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K09008
[Presentation] HNF-1αによる膵α細胞機能制御メカニズムの解明2020
- Author(s)
  佐藤叔史、モスタフィズルラーマン、羽根田昌樹、水本智也、津山友徳、吉澤達也、北村忠弘、Frank J Gonzalez、山村研一、山縣和也
- Organizer
  第63回日本糖尿病学会年次学術集会（滋賀）web開催
- Data Source
  KAKENHI-PROJECT-19K09008
[Presentation] HNF-1αによる膵α細胞機能制御メカニズムの解明2020
- Author(s)
  佐藤叔史、Md Mostafizur Rahman、羽根田昌樹、水本智也、津山友徳、吉澤達也、北村忠弘、Frank J Gonzalez、山村研一、山縣和也
- Organizer
  第63回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19H03711
[Presentation] 低酸素ストレスはBhlhe40-Mafa経路を介してインスリン分泌不全を誘導する2019
- Author(s)
  津山友徳、佐藤叔史、吉澤達也、松岡孝昭、山縣和也
- Organizer
  第42回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-19H03711
[Presentation] 低酸素誘導性BHLHE40によるβ細胞機能低下機序の解明2019
- Author(s)
  佐藤叔史、津山友徳、吉澤達也、松岡孝昭、山縣和也
- Organizer
  第62回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19H03711
[Presentation] 脱アセチル化酵素SIRT7によるNF-κB p65の核外輸送制御メカニズムの解明2019
- Author(s)
  佐藤叔史
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K09008
[Presentation] 脱アセチル化酵素SIRT7によるNF-kB p65の核外輸送制御メカニズムの解明2019
- Author(s)
  佐藤叔史、Sobuz Shihab U.、吉澤達也、Fazlul Karim、小野勝彦、澤智裕、宮本洋一、岡正啓、山縣和也
- Organizer
  第42回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-19H03711
[Presentation] 低酸素誘導性BHLHE40によるβ細胞機能低下機序の解明2019
- Author(s)
  佐藤叔史
- Organizer
  第62回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19K09008
[Presentation] Bhlhe40-Mafa経路を介した低酸素ストレスによるインスリン分泌抑制2018
- Author(s)
  津山友徳、佐藤叔史、松岡孝昭、山縣和也
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K09758
[Presentation] 低酸素応答因子HIF-1/AMPKによる膵β細胞障害の分子機構2018
- Author(s)
  佐藤叔史
- Organizer
  第91回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-16K09758
[Presentation] Bhlhe40-Mafa経路を介した低酸素ストレスによるインスリン分泌抑制2018
- Author(s)
  津山友徳、佐藤叔史、吉澤達也、松岡孝昭、山縣和也
- Organizer
  第41回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-16H05328
[Presentation] 低酸素応答因子HIF-1/AMPKによる膵β細胞障害の分子機構2018
- Author(s)
  佐藤叔史、山縣和也
- Organizer
  第91回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-16H05328
[Presentation] 膵β細胞低酸素によるHNF4蛋白低下メカニズムの解明2017
- Author(s)
  佐藤叔史、津山友徳、佐藤ちなみ、Md. Fazlul Karim、吉澤達也、井上正宏、山縣和也
- Organizer
  日本生化学学会九州支部例会
- Data Source
  KAKENHI-PROJECT-16H05328
[Presentation] 膵β細胞における低酸素誘導因子BHLHE40の機能解析2017
- Author(s)
  佐藤叔史
- Organizer
  ConBio2017
- Data Source
  KAKENHI-PROJECT-16K09758
[Presentation] Deletion of Sirtuin 7 Ameliorates Cisplatin-Induced Acute Kidney Injury through Regulation of Inflammatory Response.2016
- Author(s)
  Yoshikazu Miyasato, Tatsuya Yoshizawa, Terumasa Nakagawa, Yutaka Kakizoe, Yuichiro Izumi, Takashige Kuwabara, Masataka Adachi, Eva Bober, Masashi Mukoyama, Kazuya Yamagata
- Organizer
  The American Society of Nephrology (ASN) Kidney Week 2016 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05328
[Presentation] β細胞低酸素による転写因子HNF4α蛋白発現低下機序の検討2015
- Author(s)
  佐藤叔史、佐藤ちなみ、吉澤達也、井上正宏、山縣和也
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26860697
[Presentation] b細胞低酸素による転写因子HNF4a蛋白発現低下機序の検討2015
- Author(s)
  佐藤叔史
- Organizer
  第５８回日本糖尿病学会年次学術集会
- Place of Presentation
  山口市
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-25293212
[Presentation] 軽度低酸素による膵β細胞障害機構の検討2013
- Author(s)
  佐藤叔史, 井上正宏, 山縣和也
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  熊本
- Year and Date
  2013-05-16
- Data Source
  KAKENHI-PROJECT-24790932
[Presentation] 低酸素による糖代謝異常の解析2013
- Author(s)
  佐藤叔史
- Organizer
  第1回熊本大学医工連携フォーラム
- Place of Presentation
  熊本
- Year and Date
  2013-05-29
- Data Source
  KAKENHI-PROJECT-24790932
[Presentation] Moderate hypoxia impairs glucose stimulated insulin secretion and accelerates apoptosis in pancreatic-cellsModerate hypoxia impairs glucose stimulated insulin secretion and accelerates apoptosis in pancreaticβ-cells2013
- Author(s)
  Yoshifumi Sato, Masahiro Inoue, Kazuya Yamagata
- Organizer
  Beta Cell Workshop 2013
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24790932
[Presentation] Hypoxic stress and pancreatic β-cell dysfunction2013
- Author(s)
  Kazuya Yamagata、Yoshifumi Sato
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24790932
[Presentation] 軽度低酸素による膵β細胞障害機構の検討2013
- Author(s)
  佐藤叔史、井上正宏、山縣和也
- Organizer
  第５６回日本糖尿病学会年次学術集会
- Place of Presentation
  熊本・熊本市現代美術館
- Data Source
  KAKENHI-PROJECT-25293212
[Presentation] 軽度低酸素による膵β細胞障害機構の検討2013
- Author(s)
  佐藤叔史、井上正宏、山縣和也
- Organizer
  ：第56回日本糖尿病学会年次学術集会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24790932
[Presentation] Moderate hypoxia impairs glucose stimulated insulin secretion and accelerates apoptosis in pancreaticβ-cells.2013
- Author(s)
  Yoshifumi Sato, Masahiro Inoue, Kazuya Yamagata
- Organizer
  Beta Cell Workshop 2013
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24790932
[Presentation] 軽度低酸素による膵β細胞障害機構の検討2013
- Author(s)
  佐藤叔史、井上正宏、山縣和也
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2013-12-03
- Data Source
  KAKENHI-PROJECT-24790932
[Presentation] 軽度低酸素による膵β細胞障害機構の検討2013
- Author(s)
  佐藤叔史、井上正宏、山縣和也
- Organizer
  第３６回日本分子生物学会年会
- Place of Presentation
  神戸・神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-25293212
[Presentation] Cellular hypoxia caused dysregulation of HNF4α expression in pancreatic-β cells2012
- Author(s)
  Yoshifumi Sato
- Organizer
  The 33rd NAITO CONFERENCE
- Place of Presentation
  CHATERAISE Gateaux Kingdom SAPPORO（北海道）
- Data Source
  KAKENHI-PROJECT-24790932
[Presentation] 膵島低酸素による転写因子HNF-4αの発現低下機構の解析2012
- Author(s)
  佐藤　叔史
- Organizer
  第55回日本糖尿病学会年次学術集会
- Place of Presentation
  パシフィコ横浜（横浜）
- Data Source
  KAKENHI-PROJECT-24790932
[Presentation] 膵島低酸素による転写因子HNF-4αの発現低下機構の解析2012
- Author(s)
  佐藤叔史, 井上正宏, 下村伊一郎, 山縣和也
- Organizer
  第55回日本糖尿病学会年次学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24790932
[Presentation] Cellular hypoxia caused dysregulation of HNF4α expression in pancreatic-βcells2012
- Author(s)
  Yoshifumi Sato, Masahiro Inoue, Iichiro Shimomura, Kazuya Yamagata
- Organizer
  The 33rd NAITO CONFERENCE
- Place of Presentation
  CHA^^TERAISE^'Gateaux Kingdom SAPPORO(北海道)
- Data Source
  KAKENHI-PROJECT-24790932
[Presentation] HIF-1非依存的発現調節を介した軽度低酸素によるβ細胞障害メカニズムの検討
- Author(s)
  佐藤叔史、井上正宏、吉澤達也、山縣和也
- Organizer
  第12回がんとハイポキシア研究会
- Place of Presentation
  佐賀
- Year and Date
  2014-11-21 – 2014-11-22
- Data Source
  KAKENHI-PROJECT-26860697
[Presentation] 膵β細胞におけるHNF4α標的遺伝子Anks4bの機能解析
- Author(s)
  作永真由美、佐藤叔史、吉澤達也、山縣和也
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-05-22 – 2014-05-25
- Data Source
  KAKENHI-PROJECT-26860697
[Presentation] 膵β細胞低酸素による転写因子発現低下メカニズムの検討
- Author(s)
  佐藤叔史
- Organizer
  第５７回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-25293212
[Presentation] HIF-1非依存的発現調節を介した軽度低酸素によるβ細胞障害メカニズムの検討
- Author(s)
  佐藤叔史、井上正宏、吉澤達也、山縣和也
- Organizer
  第3７回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26860697
[Presentation] β細胞低酸素による転写因子発現低下メカニズムの検討
- Author(s)
  佐藤叔史、井上正宏、山縣和也
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-05-22 – 2014-05-25
- Data Source
  KAKENHI-PROJECT-26860697

1. YAMAGATA Kazuya (70324770)

# of Collaborated Projects: 8 results

# of Collaborated Products: 39 results
2. Yoshizawa Tatsuya (40313530)

# of Collaborated Projects: 4 results

# of Collaborated Products: 9 results
3. INOUE Masahiro (10342990)

# of Collaborated Projects: 3 results

# of Collaborated Products: 13 results
4. 津山友徳 (10845960)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
5. OKAMOTO Shiki (40342919)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. KONDOH Shinae (40314182)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 門松毅 (90555757)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 水本智也 (10985427)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. Tasaki Masayoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. Sawa Tomohiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
11. UEDA Mitsuharu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 廣田喜一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 足立健彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 荒木栄一

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
15. 近藤龍也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 山村研一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. KARIM MD・FAZLUL

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 安東由喜雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 桑原孝成

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 赤池孝章

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SATO YOSHIFUMI 佐藤 叔史

SATO Yoshifumi 佐藤 叔史

Research Projects

Research Products

Co-Researchers

サーチュイン7（SIRT7）による糖代謝制御の統合的理解とその制御法の開発

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Research Institution

Elucidation of the Incretin-Mediated Mechanism for Suppression of Hypoxia in Pancreatic beta-CellsPrincipal Investigator

Principal Investigator

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Review Section

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Elucidation of molecular mechanism of age-associated impaired insulin secretion by single cell analysis

Principal Investigator

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Review Section

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The role of ANKS4B in glucose metabolismPrincipal Investigator

Principal Investigator

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Review Section

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Regulation of glucose metabolism by SIRT7

Principal Investigator

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Review Section

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Beta-cell decompensation by chronic hypoxiaPrincipal Investigator

Principal Investigator

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Review Section

Research Institution

Identification of the metabolic roles of SIRT7 and the development of its regulation.

Principal Investigator

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Review Section

Research Institution

Pathophysiological role of pancreatic beta-cell hypoxiaPrincipal Investigator

Principal Investigator

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Identification of the multifaceted metabolic roles of SIRT7

Principal Investigator

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The pathophysiological role of pancreatic beta-cell hypoxia in the progression of diabetesPrincipal Investigator

Principal Investigator

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Molecular mechanism of diabetes mellitus based on beta-cell transcription factor network

Principal Investigator

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Proteasomal regulation of HNF4 alpha protein by hypoxia in pancreatic beta-cells.Principal Investigator

Principal Investigator

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Research Institution

[Book] 内分泌・糖尿病・代謝内科352012

Author(s)

Publisher

SATO YOSHIFUMI 佐藤叔史

SATO Yoshifumi 佐藤叔史

[Book] 実験医学増刊2012

[Book] 実験医学増刊活性酸素・ガス状分子による恒常性制御と疾患監修 : 山本雅之, 膵β細胞における低酸素応答と糖代謝異常2012