Idota Yoko 井戸田陽子

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IDOTA Yoko 井戸田陽子

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Researcher Number	90629594
Affiliation (based on the past Project Information) *help	2017: 高崎健康福祉大学, 薬学部, 研究員 2012 – 2015: 高崎健康福祉大学, 薬学部, 研究員
Review Section/Research Field	Principal Investigator Eating habits Except Principal Investigator Applied pharmacology / Medical pharmacy
Keywords	Principal Investigator 重金属 / 排泄促進 / セシウム / 結合定数 / 価数 / イオン半径 / アルギン酸 Except Principal Investigator トランスポーター / 多剤耐性 / radixin … More / P-糖タンパク / 消化管吸収 / 組織差 / 消化管がん / 腎臓がん / MRP / P-糖たんぱく / MRPs / 排出系トランスポーター / がん組織 / 足場タンパク / 網羅的な阻害 / MRPｓ / BCRP / P-gp / 脳保護作用 / シルニジピン / 脳組織移行性 / ラディキシン / 輸送活性 / 正常組織 / がん細胞 / 排出組織 / 組織選択性 / ＥＲＭタンパク / 調節因子 / 膜上発現 / 裏打ちタンパク / がん多剤耐性 / 消化管吸 / 臨床試験 / ミルク / PEPT-1 / 薬物-食物間相互作用 / 相互作用 / PEPT1 / 薬物相互作用 / 医薬品副作用 Less

Organ-specific inactivation of cancer multidrug resistance by regulating membrane scaffold proteins
- Principal Investigator
  
  Ogihara Takuo
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Takasaki University of Health and Welfare
Study of alginate's effect and mechanism, enhancing excretion and reducing absorption of strontium and cesium.Principal Investigator
- Principal Investigator
  
  Idota Yoko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Eating habits
- Research Institution
  Takasaki University of Health and Welfare
The construction of a means to overcome cancerous multidrug resistance by mediating the post-translational regulators of drug-efflux transporters
- Principal Investigator
  
  OGIHARA Takuo
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Takasaki University of Health and Welfare
Effect of Food on the Intestinal PEPT1-mediated Drug Absorption
- Principal Investigator
  
  MORIMOTO Kaori
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Takasaki University of Health and Welfare

All 2017 2016 2015 2014 2013 2011 Other

All Journal Article Presentation Book Patent

[Book] 実践製剤学－そしてその基礎となる物理薬剤学2015
- Author(s)
  安藤英紀，飯村菜穂子，石田竜弘，井戸田陽子，荻原琢男
- Total Pages
  519
- Publisher
  京都廣川書店
- Data Source
  KAKENHI-PROJECT-15K08078
[Book] 実践　製剤学　そしてその基盤となる物理薬剤学2015
- Author(s)
  安藤英紀, 飯村菜穂子, 石田竜弘, 井戸田陽子, 荻原琢男
- Total Pages
  519
- Publisher
  京都廣川書店
- Data Source
  KAKENHI-PROJECT-25560062
[Book] 薬剤学実験法必携マニュアル2014
- Author(s)
  荻原琢男、井戸田陽子
- Total Pages
  768
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-25560062
[Book] 2 試料の調製および分析法, 薬剤学実験法必携マニュアル Pharmaceutical Scientistのために Ⅱ 生物薬剤学2014
- Author(s)
  荻原琢男, 井戸田陽子
- Total Pages
  14
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-24590667
[Book] 2 試料の調製および分析法, 薬剤学実験法必携マニュアル Pharmaceutical Scientistのために Ⅱ 生物薬剤学2014
- Author(s)
  荻原琢男, 井戸田陽子
- Total Pages
  423
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-25560062
[Book] DDS製剤の開発・評価と実用化手法,2013
- Author(s)
  荻原琢男,　井戸田陽子
- Publisher
  技術情報協会
- Data Source
  KAKENHI-PROJECT-24590667
[Book] 薬剤学実験法必携マニュアル　生物薬剤学2013
- Author(s)
  荻原琢男，井戸田陽子
- Total Pages
  423
- Publisher
  日本薬剤学会出版委員会（南江堂）
- Data Source
  KAKENHI-PROJECT-24590667
[Book] ＤＤＳ製剤の開発・評価と実用化手法2013
- Author(s)
  荻原琢男，井戸田陽子
- Total Pages
  680
- Publisher
  技術情報協会
- Data Source
  KAKENHI-PROJECT-24590667
[Journal Article] Possible interaction of quinolone antibiotics with peptide transporter 1 in oral absorption of peptide-mimetic drugs.2016
- Author(s)
  Arakawa H, Kamioka H, Kanagawa M, Hatano Y, Idota Y, Yano K, Morimoto K, Ogihara T.
- Journal Title
  
  Biopharm Drug Dispos.
  
  Volume: 37 Issue: 1 Pages: 39-45
- DOI
  10.1002/bdd.1999
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08078
[Journal Article] Cholesterol-Lowering Effect of Calcium Alginate in Rats2016
- Author(s)
  Idota Y, Kogure Y, Kato T, Ogawa M, Kobayashi S, Kakinuma C, Yano K, Arakawa H, Miyajima C, Kasahara F, Ogihara T
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 39 Issue: 1 Pages: 62-67
- DOI
  10.1248/bpb.b15-00503
- NAID
  130005116495
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H02894, KAKENHI-PROJECT-25560062
[Journal Article] Interaction of Peptide Transporter 1 With d-Glucose and l-Glutamic Acid; Possible Involvement of Taste Receptors.2016
- Author(s)
  Arakawa H, Ohmachi T, Ichiba K, Kamioka H, Tomono T, Kanagawa M, Idota Y, Hatano Y, Yano K, Morimoto K, Ogihara T.
- Journal Title
  
  J Pharm Sci.
  
  Volume: 105 Issue: 1 Pages: 339-342
- DOI
  10.1016/j.xphs.2015.11.024
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08078, KAKENHI-PROJECT-25560062
[Journal Article] Characterization of Cesium Uptake Mediated by a Potassium Transport System of Bacteria in a Soil Conditioner2014
- Author(s)
  P. Zhang, Y. Idota, K. Yano, M. Negishi, H. Kawabata, H. Arakawa, K. Morimoto, A. Tsuji, T. Ogihara
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 37 Issue: 4 Pages: 604-607
- DOI
  10.1248/bpb.b13-00871
- NAID
  130003390964
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25560062
[Journal Article] The Role of Inter-segmental Differences in P-glycoprotein expression and activityalong the rat small intestine in causing the double-peak phenomenon of substrate plasma concentration2013
- Author(s)
  Wada S, Kano T, Mita S, Idota Y, Morimoto K, Yamashita F, Ogihara T.
- Journal Title
  
  Drug Metab Pharmacokinet.
  
  Volume: Vo.28 Pages: 98-103
- URL
  https://www.jstage.jst.go.jp/article/dmpk/28/2/28_DMPK-12-RG-005/_article
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590505
[Journal Article] Alginate Enhances Excretion and Reduces Absorption of Strontium and Cesium in Rats2013
- Author(s)
  Idota Y, Harada H, Tomono T, Morimoto K, Kobayashi S, Kakinuma C, Miyajima C, Kasahara F, Ogihara T
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 36 Issue: 3 Pages: 485-491
- DOI
  10.1248/bpb.b12-00899
- NAID
  130003382090
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24500969, KAKENHI-PROJECT-25560062
[Journal Article] The Role of Inter-segmental Differences in P-glycoprotein Expression and Activity along the Rat Small Intestine in Causing the Double-peak Phenomenon of Substrate Plasma Concentration2013
- Author(s)
  Sho Wada, Takashi Kano,Suzune Mita, Yoko Idota, Kaori Morimoto, Fumiyoshi Yamashita, Takuo Ogihara
- Journal Title
  
  Drug Metabolism and Pharmacokinetics
  
  Volume: 28 Issue: 2 Pages: 98-103
- DOI
  10.2133/dmpk.DMPK-12-RG-005
- NAID
  130004933523
- ISSN
  1347-4367, 1880-0920
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590667, KAKENHI-PLANNED-23136102
[Journal Article] The role of inter-segmental differences in P-glycoprotein expression and activity along the rat small intestine in causing the double-peak phenomenon of substrate plasma concentration2013
- Author(s)
  S. Wada, T. Kano, S. Mita, Y. Idota, K. Morimoto, F. Yamashita, T. Ogihara
- Journal Title
  
  Drug Metab.Pharmacokinet .
  
  Volume: 28 Pages: 98-103
- NAID
  130004933523
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590667
[Journal Article] Effect of milk on the pharmacokinetics of oseltamivir in healthy volunteers2011
- Author(s)
  Morimoto K, Kishimura K, Nagami T, Kodama N, Ogama Y, Yokoyama M, Toda S, Chiyoda T, Shimada R, Inano A, Kano T, Tamai I, Ogihara T
- Journal Title
  
  J. Pharm. Sci
  
  Volume: Vol.100 Issue: 9 Pages: 3854-3861
- DOI
  10.1002/jps.22627
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590505
[Patent] 体内のコレステロール低下剤、飲食品、飼料および医薬品2014
- Inventor(s)
  笠原文善, 宮島千尋, 荻原琢男, 井戸田陽子
- Industrial Property Rights Holder
  笠原文善, 宮島千尋, 荻原琢男, 井戸田陽子
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-123351
- Filing Date
  2014-06-16
- Data Source
  KAKENHI-PROJECT-25560062
[Presentation] P-糖タンパクを介した薬物の脳内移行性の制御 ; OseltamivirとCilnidipineの例2017
- Author(s)
  荻原琢男, 森本かおり, 井戸田陽子, 小山智志, 矢野健太郎
- Organizer
  第39回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-15K08078
[Presentation] Brain Distribution of Spermine, a Neuromodulator, and Change in the Translocation by Breast Cancer Resistance Protein2017
- Author(s)
  K. Yano, Y. Yokozuka, E. Matsumoto, S. Koyama, T. Ogihara
- Organizer
  32nd JSSX Annual Meeting
- Data Source
  KAKENHI-PROJECT-15K08078
[Presentation] ヒト腎臓がん細胞のP-gp およびMRPs 輸送機能における足場タンパクの関与2016
- Author(s)
  加藤木綿子、矢野健太郎、井戸田陽子、荒川大、荻原琢男
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-15K08078
[Presentation] Cholesterol-lowering Effect of Calcium Alginate in Rats2016
- Author(s)
  Takuo OGIHARA, Yoko IDOTA, Yumi KOGURE, Takako KATO, Mana OGAWA, Shoko KOBAYASHI, Chihaya KAKINUMA, Kentaro YANO, Hiroshi ARAKAWA, Chihiro MIYAJIMA, Fumiyoshi KASAHARA
- Organizer
  日本農芸化学会2016年度大会
- Place of Presentation
  札幌市教育文化会館（北海道札幌市）
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-25560062
[Presentation] 基質薬物とキノロン系抗菌薬との　消化管吸収過程における相互作用2015
- Author(s)
  荻原琢男, 上岡宏紀, 金川雅彦, 井戸田陽子, 矢野健太郎, 森本かおり, 荒川大
- Organizer
  第37回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  熊本大学薬学部大江キャンパス（熊本県熊本市）
- Year and Date
  2015-11-19
- Data Source
  KAKENHI-PROJECT-25560062
[Presentation] アルギン酸による重金属吸着作用の解析2015
- Author(s)
  荻原琢男, 井戸田陽子, 加藤多佳子, 矢野健太郎, 荒川大, 安竹良礼, 宮島千尋, 笠原文善
- Organizer
  第42回日本毒性学会学術年会
- Place of Presentation
  石川県立音楽堂（石川県金沢市）
- Year and Date
  2015-06-29
- Data Source
  KAKENHI-PROJECT-25560062
[Presentation] 服用者および調剤者の立場からの既存錠2錠と倍量大型錠1錠の比較検討2015
- Author(s)
  金井佑樹, 矢野健太郎, 井戸田陽子, 荒川大, 井上拓民, 林正弘, 荻原琢男
- Organizer
  第11回群馬県薬剤師学会学術大会
- Place of Presentation
  ベイシア文化ホール（群馬県前橋市）
- Year and Date
  2015-05-31
- Data Source
  KAKENHI-PROJECT-25560062
[Presentation] 初代ヒト肝細胞三次元培養法の薬物代謝酵素誘導試験における有用性2015
- Author(s)
  荒川大, 上岡宏紀, 井戸田陽子, 矢野健太郎, 荻原琢男
- Organizer
  日本薬物動態学会第30回年会
- Place of Presentation
  タワーホール船堀（東京都江戸川区）
- Year and Date
  2015-11-12
- Data Source
  KAKENHI-PROJECT-25560062
[Presentation] 基質薬物とキノロン系抗菌薬との消化管吸収過程における相互作用2015
- Author(s)
  荻原　琢男、上岡　宏紀、金川　雅彦、井戸田　陽子、矢野　健太郎、森本　かおり、荒川　大
- Organizer
  第37回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  熊本
- Year and Date
  2015-11-19
- Data Source
  KAKENHI-PROJECT-15K08078
[Presentation] Tissue-selective regulation of P-gp function in cancers by ERM proteins2015
- Author(s)
  矢野　健太郎、大塚　杏磨、加藤　木綿子、井戸田　陽子、荒川　大、荻原　琢男
- Organizer
  日本薬物動態学会第30年会
- Place of Presentation
  東京　タワーホール船堀
- Year and Date
  2015-11-12
- Data Source
  KAKENHI-PROJECT-15K08078
[Presentation] Utility of three-dimensional culture of human hepatocyte as a tool of drug metabolizing enzyme induction2015
- Author(s)
  荒川　大、上岡　宏紀、井戸田　陽子、矢野　健太郎、荻原　琢男
- Organizer
  日本薬物動態学会第30年会
- Place of Presentation
  東京　タワーホール船堀
- Year and Date
  2015-11-12
- Data Source
  KAKENHI-PROJECT-15K08078
[Presentation] アルギン酸による血中コレステロール低下作用2014
- Author(s)
  安竹良礼, 井戸田陽子, 木暮悠美, 加藤多佳子, 矢野健太郎, 荒川大, 柿沼千早, 宮島千尋, 笠原文善, 小林彰子, 荻原琢男
- Organizer
  第58回日本薬学会関東支部大会
- Place of Presentation
  東京
- Year and Date
  2014-10-04
- Data Source
  KAKENHI-PROJECT-25560062
[Presentation] Alginate Enhances Excretion and Reduces Absorption of Strontium and Cesium in Rats2013
- Author(s)
  Yumi Kogure, Yoko Idota, Hitomi Harada, Shoko Kobayashi, Chihaya Kakinuma, Chihiro Miyajima, Fumiyoshi Kasahara, Takuo Ogihara
- Organizer
  Asian Federation for Pharmaceutical Sciences (AFPS) 2013 -アジア薬科学会議2013-
- Place of Presentation
  済州島, 韓国
- Data Source
  KAKENHI-PROJECT-25560062
[Presentation] Contribution of radixin to P-glycoprotein expression and transport activity2013
- Author(s)
  Yano K, Tomono T, Kawabata H, Idota Y, Morimoto K, Arakawa H, Ogihara T
- Organizer
  28ｔｈ JSSX Annual Meeting,
- Place of Presentation
  Ｔｏｋｙｏ
- Data Source
  KAKENHI-PROJECT-24590667
[Presentation] In　vitroによる薬物代謝スクリーニングの現状と留意点,2013
- Author(s)
  荻原琢男,　井戸田陽子
- Organizer
  第40回日本毒性学会学術年会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-24590667
[Presentation] Effects of Calcium Alginate on Lowering Cholesterol in Rats
- Author(s)
  T. Yasutake, Y. Idota, Y. Kogure, T. Kato, K. Yano, H. Arakawa, C. Kakinuma, C. Miyajima, F. Kasahara, S. Kobayashi, T. Ogihara
- Organizer
  第2回薬食国際カンファレンス
- Place of Presentation
  静岡
- Year and Date
  2014-11-05 – 2014-11-06
- Data Source
  KAKENHI-PROJECT-25560062
[Presentation] SSRIおよびSNRIによるK+チャネル阻害作用のPK/PD解析
- Author(s)
  伴野拓巳, 橋場弘武, 矢野健太郎, 井戸田陽子, 荒川大, 林正弘, 荻原琢男
- Organizer
  第24回日本医療薬学会年会
- Place of Presentation
  名古屋
- Year and Date
  2014-09-27 – 2014-09-28
- Data Source
  KAKENHI-PROJECT-25560062
[Presentation] アルギン酸による重金属吸着作用の解析
- Author(s)
  荻原琢男，加藤多佳子，井戸田陽子，矢野健太郎，荒川大，安竹良礼，宮島千尋，笠原文善
- Organizer
  第42回日本毒性学会学術年会
- Place of Presentation
  金沢
- Year and Date
  2015-06-29 – 2015-07-01
- Data Source
  KAKENHI-PROJECT-25560062
[Presentation] アルギン酸による重金属の吸収抑制および排泄促進作用とそのメカニズムの検討
- Author(s)
  荻原琢男, 井戸田陽子, 木暮悠美, 原田瞳, 河合妙子, 矢野健太郎, 柿沼千早, 宮島千尋, 笠原文善
- Organizer
  第41回日本毒性学会学術年会
- Place of Presentation
  神戸
- Year and Date
  2014-07-02 – 2014-07-04
- Data Source
  KAKENHI-PROJECT-25560062
[Presentation] 高リン血症治療薬に対する併用注意剤の吸着性解析
- Author(s)
  安部有紀, 伴野拓巳, 秋山滋男, 井戸田陽子, 矢野健太郎, 荒川大, 磯野淳一, 林正弘, 荻原琢男
- Organizer
  第24回日本医療薬学会年会
- Place of Presentation
  名古屋
- Year and Date
  2014-09-27 – 2014-09-28
- Data Source
  KAKENHI-PROJECT-25560062
[Presentation] P-glycoprotein Plays a Key Role in the Contractionary Effects against Brain Infarction of
- Author(s)
  Takumi Tomono, Kentaro Yano, Toshimitsu Motegi, Shinobu Takimoto, Mihoko Hagiwara, Yoko Idota, Takashi Kano, Hiroshi Arakawa, Kaori Morimoto, Chihaya Kakinuma, Akira Takahara, Takuo Ogihara
- Organizer
  19th North American ISSX/29th JSSX Meeting
- Place of Presentation
  サンフランシスコ
- Year and Date
  2014-10-19 – 2014-10-23
- Data Source
  KAKENHI-PROJECT-24590667

1. OGIHARA Takuo (80448886)

# of Collaborated Projects: 4 results

# of Collaborated Products: 34 results
2. MORIMOTO Kaori (90401009)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
3. KENTARO Yano (40644290)

# of Collaborated Projects: 3 results

# of Collaborated Products: 21 results
4. KANO Takashi (70509257)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. MASAHIRO Kajita (40591871)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. ZHANG Pengyao (80643311)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. Arakawa Hiroshi (40709028)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results

Idota Yoko 井戸田 陽子

IDOTA Yoko 井戸田 陽子

Research Projects

Research Products

Co-Researchers

Organ-specific inactivation of cancer multidrug resistance by regulating membrane scaffold proteins

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study of alginate's effect and mechanism, enhancing excretion and reducing absorption of strontium and cesium.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The construction of a means to overcome cancerous multidrug resistance by mediating the post-translational regulators of drug-efflux transporters

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Effect of Food on the Intestinal PEPT1-mediated Drug Absorption

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[Book] 実践製剤学－そしてその基礎となる物理薬剤学2015

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[Book] 実践 製剤学 そしてその基盤となる物理薬剤学2015

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[Book] 薬剤学実験法必携マニュアル2014

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[Book] 2 試料の調製および分析法, 薬剤学実験法必携マニュアル Pharmaceutical Scientistのために Ⅱ 生物薬剤学2014

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[Book] 2 試料の調製および分析法, 薬剤学実験法必携マニュアル Pharmaceutical Scientistのために Ⅱ 生物薬剤学2014

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[Book] DDS製剤の開発・評価と実用化手法,2013

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[Book] 薬剤学実験法必携マニュアル 生物薬剤学2013

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[Book] ＤＤＳ製剤の開発・評価と実用化手法2013

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[Journal Article] Possible interaction of quinolone antibiotics with peptide transporter 1 in oral absorption of peptide-mimetic drugs.2016

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[Journal Article] Cholesterol-Lowering Effect of Calcium Alginate in Rats2016

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Idota Yoko 井戸田陽子

IDOTA Yoko 井戸田陽子

[Book] 実践　製剤学　そしてその基盤となる物理薬剤学2015

[Book] 薬剤学実験法必携マニュアル　生物薬剤学2013