YOSHINO Hirofumi 吉野裕史

… Alternative Names

吉野裕史ヨシノヒロフミ

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Researcher Number	90642611
Affiliation (Current)	2025: 鹿児島大学, 医歯学域医学系, 講師
Affiliation (based on the past Project Information) *help	2021 – 2024: 鹿児島大学, 医歯学域医学系, 講師 2021: 鹿児島大学, 医歯学域鹿児島大学病院, 助教 2020: 鹿児島大学, 医歯学域医学系, 助教 2019: 鹿児島大学, 医歯学域鹿児島大学病院, 助教 2018: 鹿児島大学, 医歯学域附属病院, 助教 … More 2017: 鹿児島大学, 医学部・歯学部附属病院, その他(移行) 2017: 鹿児島大学, 医歯学総合研究科, 客員研究員 2016: 鹿児島大学, 附属病院, 医員 2013: 鹿児島大学, 医学部・歯学部附属病院, 医員 Less
Review Section/Research Field	Principal Investigator Urology / Basic Section 56030:Urology-related / Basic Section 50020:Tumor diagnostics and therapeutics-related Except Principal Investigator Basic Section 56030:Urology-related / Urology
Keywords	Principal Investigator 尿路上皮癌 / 腎細胞癌 / マイクロRNA / エクソソーム / ドラッグリポジショニング / ユビキチンプロテアソーム / NPL4 / ジスルフィラム / 腎癌 / シグナル伝達 … More / 核酸 / 癌 / 治療標的型マイクロRNA / miRNA-223 / miRNA-199 / 癌抑制遺伝子 … More Except Principal Investigator マイクロRNA / 膀胱癌 / 尿路上皮癌 / microRNA / 薬剤耐性 / WDR62 / ゲノム編集 / 腎癌 / MYO15A / microRNA-1 / 腎細胞癌 / エクソソーム / 抗体複合薬 / 腫瘍マーカー / 抗癌剤耐性 / miR-223 / PHGDH / SMARCD1 / miR-99a-5p / ジェムシタビン耐性 / ジェムシタビン / シスプラチン / 高分子ナノミセル / 核酸医薬 / miR-1 / miR-218 / ドラッグデリバリー / ナノミセル / ゲノム / 進行性膀胱癌 / ゲノム編集技術 / 膀胱がん / miRNA 223 / 癌遺伝子 / CRISPR/Cas9 Less

膀胱癌治療における代謝リプログラミングの探求と新たな治療アプローチの提案
- Principal Investigator
  
  松下良介
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Kagoshima University
エクソソーム含有核酸の測定による尿路上皮癌の新規体液診断の開発Principal Investigator
- Principal Investigator
  
  吉野裕史
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Kagoshima University
多面的解析による尿路上皮癌における抗体複合薬の耐性機序の解明と耐性克服戦略の構築
- Principal Investigator
  
  中川昌之
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Kagoshima University
エクソソーム解析による治療抵抗性腎癌の新規治療戦略と治療効果予測マーカーの開発
- Principal Investigator
  
  鑪野秀一
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Kagoshima University
Development of a new diagnostic method for urothelial carcinoma by detecting urinary microRNA using cell sorting system
- Principal Investigator
  
  ENOKIDA Hideki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Kagoshima University
Targeting the Ubiquitin Proteasome Pathway as a Novel Therapeutic Strategy for Advanced Renal Cell CarcinomaPrincipal Investigator
- Principal Investigator
  
  YOSHINO Hirofumi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kagoshima University
Elucidating anticancer drug resistance in urothelial carcinoma by multi-faceted approach
- Principal Investigator
  
  NAKAGAWA Masayuki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Kagoshima University
New oligonucleotide therapeutics using polymeric nano-micelles conjugated with tumor suppressive microRNA in bladder cancer
- Principal Investigator
  
  YAMADA Yasutoshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Kagoshima University
Functional analysis of the oncogenic microRNA by the genome editing aiming at the development of the innovative renal cancer treatment
- Principal Investigator
  
  ITESAKO Toshihiko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Kagoshima University
Functional analyses of oncogenic microRNA by genome editing and development of innovative genome-based drug discovery for bladder cancer.
- Principal Investigator
  
  ENOKIDA Hideki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  Kagoshima University
Development of the innovative treatment based on the search of microRNA blocking growth signals in urothelial carcinomaPrincipal Investigator
- Principal Investigator
  
  YOSHINO Hirofumi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Kagoshima University
Investigation of the molecular network regulated by novel tumor suppressive microRNAs in bladder cancer
- Principal Investigator
  
  MATSUSHITA Ryosuke
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Urology
- Research Institution
  Kagoshima University
治療抵抗性腎細胞癌の新規治療法開発に向けた機能性RNAネットワークの解明Principal Investigator
- Principal Investigator
  
  吉野裕史
- Project Period (FY)
  2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Urology
- Research Institution
  Kagoshima University

All 2023 2022 2021 2020 2019 2018 2017 2016 2013 Other

All Journal Article Presentation Other

[Journal Article] Characterization and treatment of gemcitabine‐ and cisplatin‐resistant bladder cancer cells with a pan‐RAS inhibitor2023
- Author(s)
  Yoshino Hirofumi、Yokoyama Seiya、Tamai Motoki、Okamura Shunsuke、Iizasa Sayaka、Sakaguchi Takashi、Osako Yoichi、Inoguchi Satoru、Matsushita Ryosuke、Yamada Yasutoshi、Nakagawa Masayuki、Tatarano Shuichi、Tanimoto Akihide、Enokida Hideki
- Journal Title
  
  FEBS Open Bio
  
  Volume: 13 Issue: 6 Pages: 1056-1066
- DOI
  10.1002/2211-5463.13616
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09452, KAKENHI-PROJECT-22K09478, KAKENHI-PROJECT-21K09404, KAKENHI-PROJECT-21K09430, KAKENHI-PROJECT-22K16792, KAKENHI-PROJECT-22K16805
[Journal Article] Potential therapeutic target secretogranin II might cooperate with hypoxia‐inducible factor 1α in sunitinib‐resistant renal cell carcinoma2023
- Author(s)
  Fukumoto Wataru、Yoshino Hirofumi、Horike Shin‐Ichi、Kawakami Issei、Tamai Motoki、Arima Junya、Kawahara Ichiro、Mitsuke Akihiko、Sakaguchi Takashi、Inoguchi Satoru、Meguro‐Horike Makiko、Tatarano Shuichi、Enokida Hideki
- Journal Title
  
  Cancer Science
  
  Volume: 114 Issue: 10 Pages: 3946-3956
- DOI
  10.1111/cas.15914
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16820, KAKENHI-PROJECT-22K06896, KAKENHI-PROJECT-22K09452, KAKENHI-PROJECT-22K09507, KAKENHI-PROJECT-21K09430, KAKENHI-PROJECT-22K16792, KAKENHI-PROJECT-22K16805
[Journal Article] microRNA-99a-5p induces cellular senescence in gemcitabine-resistant bladder cancer by targeting SMARCD12022
- Author(s)
  Motoki Tamai, Shuichi Tatarano, Shunsuke Okamura, Wataru Fukumoto, Issei Kawakami, Yoichi Osako, Takashi Sakaguchi, Satoshi Sugita, Masaya Yonemori, Yasutoshi Yamada, Masayuki Nakagawa, Hideki Enokida, Hirofumi Yoshino.
- Journal Title
  
  Molecular Oncology
  
  Volume: 16 Pages: 1329-1346
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09404
[Journal Article] Targeting of the glutamine transporter SLC1A5 induces cellular senescence in clear cell renal cell carcinoma2022
- Author(s)
  Issei Kawakami, Hirofumi Yoshino, Wataru Fukumoto, Motoki Tamai, Shunsuke Okamura, Yoichi Osako, Takashi Sakaguchi, Satoru Inoguchi, Ryosuke Matsushita, Yasutoshi Yamada, Shuichi Tatarano, Masayuki Nakagawa, Hideki Enokida.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: - Pages: 99-106
- DOI
  10.1016/j.bbrc.2022.04.068
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07736, KAKENHI-PROJECT-21K09430, KAKENHI-PROJECT-22K09452, KAKENHI-PROJECT-22K16792, KAKENHI-PROJECT-22K16805, KAKENHI-PROJECT-22K16820
[Journal Article] Exosomal microRNA-1 and MYO15A as a target for therapy and diagnosis in renal cell carcinoma2022
- Author(s)
  Yoshino Hirofumi、Tatarano Shuichi、Tamai Motoki、Tsuruda Masafumi、Iizasa Sayaka、Arima Junya、Kawakami Issei、Fukumoto Wataru、Kawahara Ichiro、Li Gang、Sakaguchi Takashi、Inoguchi Satoru、Yamada Yasutoshi、Enokida Hideki
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 630 Pages: 71-76
- DOI
  10.1016/j.bbrc.2022.09.056
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09430, KAKENHI-PROJECT-22K09452, KAKENHI-PROJECT-22K09507, KAKENHI-PROJECT-22K16792
[Journal Article] microRNA-99a-5p induces cellular senescence in gemcitabine-resistant bladder cancer by targeting SMARCD1.2022
- Author(s)
  Motoki Tamai, Shuichi Tatarano, Shunsuke Okamura, Wataru Fukumoto, Issei Kawakami, Yoichi Osako, Takashi Sakaguchi, Satoshi Sugita, Masaya Yonemori, Yasutoshi Yamada, Masayuki Nakagawa, Hideki Enokida, Hirofumi Yoshino.
- Journal Title
  
  Molecular Oncology
  
  Volume: 16 Issue: 6 Pages: 1329-1346
- DOI
  10.1002/1878-0261.13192
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09715, KAKENHI-PROJECT-20K18146, KAKENHI-PROJECT-21K09404, KAKENHI-PROJECT-22K09452, KAKENHI-PROJECT-22K09478
[Journal Article] EHHADH contributes to cisplatin resistance through regulation by tumor-suppressive microRNAs in bladder cancer2021
- Author(s)
  Okamura Shunsuke、Yoshino Hirofumi、Kuroshima Kazuki、Tsuruda Masafumi、Osako Yoichi、Sakaguchi Takashi、Yonemori Masaya、Yamada Yasutoshi、Tatarano Shuichi、Nakagawa Masayuki、Enokida Hideki
- Journal Title
  
  BMC Cancer
  
  Volume: 21 Issue: 1 Pages: 48-48
- DOI
  10.1186/s12885-020-07717-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K18146, KAKENHI-PROJECT-18K09198, KAKENHI-PROJECT-19K18615
[Journal Article] Oncogenic effects of RAB27B through exosome independent function in renal cell carcinoma including sunitinib-resistant2020
- Author(s)
  Tsuruda Masafumi、Yoshino Hirofumi、Okamura Shunsuke、Kuroshima Kazuki、Osako Yoichi、Sakaguchi Takashi、Sugita Satoshi、Tatarano Shuichi、Nakagawa Masayuki、Enokida Hideki
- Journal Title
  
  PLOS ONE
  
  Volume: 15 Issue: 5 Pages: e0232545-e0232545
- DOI
  10.1371/journal.pone.0232545
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07736, KAKENHI-PROJECT-18K09198
[Journal Article] Potential new therapy of Rapalink-1, a new generation mTOR inhibitor, against sunitinib-resistant renal cell carcinoma.2020
- Author(s)
  Kuroshima K, Yoshino H, Okamura S, Tsuruda M, Osako Y, Sakaguchi T, Sugita S, Tatarano S, Nakagawa M, Enokida H.
- Journal Title
  
  Cancer Science
  
  Volume: Epub ahead of print Issue: 5 Pages: 1607-1618
- DOI
  10.1111/cas.14395
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07736
[Journal Article] Characterization of PHGDH expression in bladder cancer: potential targeting therapy with gemcitabine/cisplatin and the contribution of promoter DNA hypomethylation2020
- Author(s)
  Hirofumi Yoshino, Hideki Enokida, Yoichi Osako, Nijiro Nohata, Masaya Yonemori, Satoshi Sugita, Kazuki Kuroshima, Masafumi Tsuruda, Shuichi Tatarano, Masayuki Nakagawa.
- Journal Title
  
  Molecular Oncology
  
  Volume: 54 Issue: 9 Pages: 2190-2202
- DOI
  10.1002/1878-0261.12697
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09715, KAKENHI-PROJECT-20K18146, KAKENHI-PROJECT-18K09198, KAKENHI-PROJECT-19K18615
[Journal Article] Targeting NPL4 via drug repositioning using disulfiram for the treatment of clear cell renal cell carcinoma2020
- Author(s)
  Yoshino Hirofumi、Yamada Yasutoshi、Enokida Hideki、Osako Yoichi、Tsuruda Masafumi、Kuroshima Kazuki、Sakaguchi Takashi、Sugita Satoshi、Tatarano Shuichi、Nakagawa Masayuki
- Journal Title
  
  PLOS ONE
  
  Volume: 15 Issue: 7 Pages: e0236119-e0236119
- DOI
  10.1371/journal.pone.0236119
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07736
[Journal Article] HRAS as a potential therapeutic target of salirasib RAS inhibitor in bladder cancer.2019
- Author(s)
  Sugita S, Enokida H, Yoshino H, Miyamoto K, Yonemori M, Sakaguchi T, Osako Y, Nakagawa M.
- Journal Title
  
  Int J Oncol.
  
  Volume: 53 Pages: 725-736
- DOI
  10.3892/ijo.2018.4435
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04332, KAKENHI-PROJECT-17K16799
[Journal Article] Potential tumor-suppressive role of microRNA-99-3p in sunitinib-resistant renal cell carcinoma cells through the regulation of RRM22019
- Author(s)
  Osako Y, Yoshino H, Sakaguchi T, Sugita S, Yonemori M, Nakagawa M, Enokida H.
- Journal Title
  
  International Journal of Oncology
  
  Volume: 54 Pages: 1759-1770
- DOI
  10.3892/ijo.2019.4736
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05464, KAKENHI-PROJECT-17K16799, KAKENHI-PROJECT-19K07736, KAKENHI-PROJECT-19K18615, KAKENHI-PROJECT-17K11148
[Journal Article] Tumor-suppressive microRNA-223 targets WDR62 directly in bladder cancer.2019
- Author(s)
  Sugita S, Yoshino H, Yonemori M, Miyamoto K, Matsushita R, Sakaguchi T, Itesako T, Tatarano S, Nakagawa M, Enokida H.
- Journal Title
  
  Int J Oncol.
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11015
[Journal Article] Potential tumor-suppressive role of microRNA-99a-3p in sunitinib-resistant renal cell carcinoma cells through the regulation of RRM2.2019
- Author(s)
  Osako Y, Yoshino H, Sakaguchi T, Sugita S, Yonemori M, Nakagawa M, Enokida H.
- Journal Title
  
  Int J Oncol.
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11015
[Journal Article] Tumor-suppressive microRNA-223 targets WDR62 directly in bladder cancer.2019
- Author(s)
  Sugita S, Yoshino H, Yonemori M, Miyamoto K, Matsushita R, Sakaguchi T, Itesako T, Tatarano S, Nakagawa M, Enokida H.
- Journal Title
  
  Int J Oncol.
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11148
[Journal Article] Tumor suppressive microRNA223 targets WDR62 directly in bladder cancer.2019
- Author(s)
  Sugita S, Yoshino H, Yonemori M, Miyamoto K, Matsushita R, Sakaguchi T, Itesako T, Tatarano S, Nakagawa M, Enokida H.
- Journal Title
  
  Int J Oncol.
  
  Volume: 54 Pages: 2222-2236
- DOI
  10.3892/ijo.2019.4762
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04332, KAKENHI-PROJECT-17K16799, KAKENHI-PROJECT-19K07736, KAKENHI-PROJECT-19K09715, KAKENHI-PROJECT-19K18615
[Journal Article] Regulation of ITGA3 by the dual-stranded microRNA-199 family as a potential prognostic marker in bladder cancer.2018
- Author(s)
  Sakaguchi T, Yoshino H, Yonemori M, Miyamoto K, Sugita S, Matsushita R, Itesako T, Tatarano S, Nakagawa M, Enokida H.
- Journal Title
  
  Br J Cancer
  
  Volume: 118
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11148
[Journal Article] Bromodomain protein BRD4 inhibitor JQ1 regulates potential prognostic molecules in advanced renal cell carcinoma.2018
- Author(s)
  Sakaguchi T, Yoshino H, Sugita S, Miyamoto K, Yonemori M, Osako Y, Meguro-Horike M, Horike SI, Nakagawa M, Enokida H.
- Journal Title
  
  Oncotarget
  
  Volume: 9 Pages: 23003-23017
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11015
[Journal Article] Downregulation of microRNA-1274a induces cell apoptosis through regulation of2018
- Author(s)
  Yoshino H, Yonezawa T, Yonemori M, Miyamoto K, Sakaguchi T, Sugita S, Osako Y, Tatarano S, Nakagawa M, Enokida H.
- Journal Title
  
  Oncol Rep
  
  Volume: 39 Pages: 173-181
- DOI
  10.3892/or.2017.6098
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11015, KAKENHI-PROJECT-16K15691, KAKENHI-PROJECT-17K16799, KAKENHI-PROJECT-16H05464
[Journal Article] HRAS as a potential therapeutic target of salirasib RAS inhibitor in bladder cancer.2018
- Author(s)
  Sugita S, Enokida H, Yoshino H, Miyamoto K, Yonemori M, Sakaguchi T, Osako Y, Nakagawa M.
- Journal Title
  
  Int J Oncol.
  
  Volume: 53 Pages: 725-736
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11015
[Journal Article] microRNA-210-3p depletion by CRISPR/Cas9 promoted tumorigenesis through revival of TWIST1 in renal cell carcinoma.2017
- Author(s)
  Yoshino H, Yonemori M, Miyamoto K, Tatarano S, Kofuji S, Nohata N, Nakagawa M, Enokida H.
- Journal Title
  
  Oncotarget
  
  Volume: 8 Issue: 13 Pages: 20881-20894
- DOI
  10.18632/oncotarget.14930
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05464, KAKENHI-PROJECT-16K11015, KAKENHI-PROJECT-17K16799
[Journal Article] PHGDH as a Key Enzyme for Serine Biosynthesis in HIF2α-Targeting Therapy for　Renal Cell Carcinoma.2017
- Author(s)
  Yoshino H, Nohata N, Miyamoto K, Yonemori M, Sakaguchi T, Sugita　S, Itesako T, Kofuji S, Nakagawa M, Dahiya R, Enokida H.
- Journal Title
  
  Cancer Res
  
  Volume: 77 Pages: 6321-6329
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11148
[Journal Article] Regulation of ITGA3 by the dual-stranded microRNA-199 family as a potential prognostic marker in bladder cancer.2017
- Author(s)
  Sakaguchi T, Yoshino H, Yonemori M, Miyamoto K, Sugita S, Matsushita R, Itesako T, Tatarano S, Nakagawa M, Enokida H.
- Journal Title
  
  British Journal of Cancer
  
  Volume: 116 Issue: 8 Pages: 1077-1087
- DOI
  10.1038/bjc.2017.43
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293354, KAKENHI-PROJECT-16K11015, KAKENHI-PROJECT-16K15691, KAKENHI-PROJECT-17H04332, KAKENHI-PROJECT-16K20145
[Journal Article] PHGDH as a Key Enzyme for Serine Biosynthesis in HIF2α-Targeting Therapy for2017
- Author(s)
  Yoshino H, Nohata N, Miyamoto K, Yonemori M, Sakaguchi T, Sugita S, Itesako T, Kofuji S, Nakagawa M, Dahiya R, Enokida H.
- Journal Title
  
  Cancer Res
  
  Volume: 77 Pages: 6321-6329
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11015
[Journal Article] Tumour-suppressive miRNA-26a-5p and miR-26b-5p inhibit cell aggressiveness by regulating PLOD2 in bladder cancer2016
- Author(s)
  Miyamoto K, Seki N, Matsushita R, Yonemori M, Yoshino H, Nakagawa M, Enokida H.
- Journal Title
  
  British Journal of Cancer
  
  Volume: 115 Issue: 3 Pages: 354-363
- DOI
  10.1038/bjc.2016.179
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26293354, KAKENHI-PROJECT-26462416, KAKENHI-PROJECT-16K11015, KAKENHI-PROJECT-16K20145
[Journal Article] Dual tumor-suppressors miR-139-5p and miR-139-3p targeting matrix metalloprotease 11 in bladder cancer.2016
- Author(s)
  Yonemori M, Seki N, Yoshino H, Matsushita R, Miyamoto K, Nakagawa M, Enokida H.
- Journal Title
  
  Cancer Science
  
  Volume: 107 Issue: 9 Pages: 1233-1242
- DOI
  10.1111/cas.13002
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26293354, KAKENHI-PROJECT-16K11015, KAKENHI-PROJECT-16K20145
[Journal Article] Epithelial-mesenchymal transition-related microRNA-200s regulate molecular targets and pathways in renal cell carcinoma.2013
- Author(s)
  Hirofumi Yoshino
- Journal Title
  
  Journal of human genetics
  
  Volume: 58 Pages: 508-516
- NAID
  10031195279
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25861430
[Presentation] BCYRN1 can be a target for diagnosis and therapy in renal cell carcinoma.2023
- Author(s)
  Yoshino H, Arima J, Fukumoto W, Kawahara I, Tatarano S, Enokida H
- Organizer
  American Urological Association Annual Meeting (AUA2023), Chicago, USA, 2023.4.28.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09452
[Presentation] Exosomal lncRNA BCYRN1 as a target for diagnosis and therapy in renal cell carcinoma2023
- Author(s)
  Hirofumi Yoshino, Junya Arima, Wataru Fukumoto, Ichiro Kawahara, Shuichi Tatarano, Hideki Enokida
- Organizer
  European Association or Urology 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09452
[Presentation] Exosomal antitumor microRNA-1 as a therapeutic target and a tumor marker in renal cell carcinoma2022
- Author(s)
  Hirofumi Yoshino, Motoki Tamai, Issei Kawakami, Shuichi Tatarano, Hideki Enokida
- Organizer
  European Association or Urology 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09452
[Presentation] グルタミントランスポーター SLC1A5 を標的とした進行性腎細胞癌に対する新規治療戦略の開発2022
- Author(s)
  川上一誠, 吉野裕史, 福元渉, 玉井元規, 岡村俊介, 鑪野秀一, 榎田英樹
- Organizer
  第31回泌尿器科分子・細胞研究会
- Data Source
  KAKENHI-PROJECT-19K07736
[Presentation] PHGDHを標的とした新規膀胱癌治療の可能性とその発現機構の解明2021
- Author(s)
  吉野裕史, 大迫洋一, 鶴田雅史, 黒島和樹, 岡村俊介, 榎田英樹, 中川昌之.
- Organizer
  第30回泌尿器科分子・細胞研究会
- Data Source
  KAKENHI-PROJECT-18K09198
[Presentation] microRNA-99a-5pは、膀胱癌におけるゲムシタビン耐性を克服するための重要な分子である.2021
- Author(s)
  玉井元規, 吉野裕史, 坂口大, 榎田英樹.
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K09715
[Presentation] microRNA-99a-5pは、膀胱癌におけるゲムシタビン耐性を克服するための重要な分子である.2021
- Author(s)
  玉井元規, 吉野裕史, 坂口大, 榎田英樹.
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K09404
[Presentation] グルタミントランスポーター SLC1A5 を標的とした進行性腎細胞癌に対する新規治療戦略の開発2021
- Author(s)
  川上一誠, 吉野裕史, 岡村俊介, 玉井元規, 榎田英樹, 中川昌之
- Organizer
  第109回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-19K07736
[Presentation] 腎細胞癌における新世代mTOR阻害剤Rapalink-1の治療効果の基礎的検討2020
- Author(s)
  黒島和樹, 吉野裕史, 岡村俊介, 鶴田雅史, 大迫洋一, 榎田英樹, 中川昌之.
- Organizer
  第108回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-19K07736
[Presentation] スニチニブ耐性腎癌に対する新規治療法2020
- Author(s)
  吉野裕史, 岡村俊介, 榎田英樹, 中川昌之.
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07736
[Presentation] Efficacy and Safety of Brachytherapy in Japanese PCa patients: A single-institution results2019
- Author(s)
  Hirofumi Yoshino
- Organizer
  米国泌尿器科学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07736
[Presentation] Targeting PHGDH exerts anti-oncogenic effects in bladder cancer2019
- Author(s)
  Hirofumi Yoshino
- Organizer
  欧州泌尿器科学
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11015
[Presentation] ドラッグリポジショニングを目的とした腎細胞癌に対する新規治療戦略の構築2019
- Author(s)
  吉野裕史
- Organizer
  日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-19K07736
[Presentation] Targeting PHGDH exerts anti-omcogenic effects in bladder cncer.2019
- Author(s)
  Yoshino H
- Organizer
  第34回欧州泌尿器学会議（EAU19）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11148
[Presentation] Targeting metabolism re-programming as a therapy for drug-resistant renal cell carcinoma2018
- Author(s)
  Hirofumi Yoshino, Kazutaka Miyamoto, Masaya Yonemori, Satoru Sugita, Takashi Sakaguchi, Hideki Enokida, Masayuki Nakagawa
- Organizer
  欧州泌尿器科学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11015
[Presentation] 膀胱癌におけるRAS阻害剤Salirasibを介した治療標的としてのHRAS2018
- Author(s)
  杉田智，吉野裕史，宮元一隆，大迫洋一，坂口大，米森雅也，榎田英樹，中川昌之．
- Organizer
  第106回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-17H04332
[Presentation] CRISPR/Cas9-mediated miR-20-3p depletion promoted tumorigenesis through revival of TWIST in renal cell carcinoma2017
- Author(s)
  Hirofumi Yoshino, Masaya Yonemori, Kazutaka Miyamoto, Satoshi Kofuji, Nijiro Nohata, Hideki Enokida, Masayuki Nakagawa
- Organizer
  米国泌尿器科学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11015
[Presentation] CRISPR/CAas9によるmicroRNA編集による腎癌の進展メカニズムの解明2017
- Author(s)
  吉野裕史、米森雅也、宮元一隆、榎田英樹、中川昌之
- Organizer
  日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-16K11015
[Presentation] Tumor-suppressive microRNA-26a-5p/-26b-5p inhibit cancer cell migration and invasion through targeting PLOD2 that is a potential prognostic marker in bladder cancer.2017
- Author(s)
  Miyamoto K, Seki N, Matsushita R, Yonemori M, Yoshino H, Sakaguchi T, Sugita S, Enokida H, Nakagawa M.
- Organizer
  American Urological Association (AUA) annual meeting
- Place of Presentation
  Boston (USA)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20145
[Presentation] Tumor-suppressive microRNA-26a-5p/-26b-5p inhibit cancer cell migration and invasion through targeting PLOD2 that is a potential prognostic marker in bladder cancer2017
- Author(s)
  Kazutaka Miyamoto, Kagoshima, Japan, Naohiko Seki, Ryosuke Matsushita, Masaya Yonemori, Hirofumi Yoshino, Takashi Sakaguchi, Satoshi Sugita, Hideki Enokida, Masayuki Nakagawa
- Organizer
  米国泌尿器科学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20145
[Presentation] 膀胱癌におけるIntegrin α3（ITGA3）制御を介したmicroRNA-199 familyの癌抑制的作用2017
- Author(s)
  坂口大、吉野裕史、米森雅也、宮元一隆、杉田智、松下良介、榎田英樹、中川昌之
- Organizer
  第105回日本泌尿器科学会総会
- Place of Presentation
  かごしま県民交流センター（鹿児島県鹿児島市）
- Year and Date
  2017-04-21
- Data Source
  KAKENHI-PROJECT-16K11015
[Presentation] Dual-strands of microRNA-139 (miR-139-5p and miR-139-3p) targeting matrix metalloprotease 11 (MMP11) in bladder cancer2016
- Author(s)
  Yonemori M, Seki N, Yoshino H, Matsushita R, Miyamoto K, Nakagawa M, Enokida H.
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16K11015
[Presentation] Dual tumor-suppressors miR-139-5p/-3p derived from pre-miR-139 via targeting matrix metalloprotease 11 (MMP11) in bladder cancer2016
- Author(s)
  Yonemori M, Seki N, Matsushita R, Miyamoto K, Yoshino H, Goto Y, Kato M, Kurozumi A, Nakagawa M, Enokida H
- Organizer
  American Urological Association (AUA) annual meeting
- Place of Presentation
  San Diego (USA)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20145
[Presentation] Tumor suppressive miRNA-26a/b inhibit cell migration and invasion through targeting a prognostic marker, Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 (PLOD2) in bladder cancer.2016
- Author(s)
  Miyamoto K, Seki N, Matsushita R, Yonemori M, Yoshino H, Nakagawa M, Enokida H.
- Organizer
  第68回西日本泌尿器科学会
- Place of Presentation
  海峡メッセ下関（山口県下関市）
- Year and Date
  2016-11-24
- Data Source
  KAKENHI-PROJECT-16K11015
[Presentation] Dual tumor-suppressors (miR-145-5p/miR-145-3p) inducing cancer cell apoptosis via direct targeting UHRF1 in bladder cancer2016
- Author(s)
  Matsushita R, Seki N, Yoshino H, Miyamoto K, Yonemori M, Kurozumi A, Goto Y, Enokida H, Nakagawa M.
- Organizer
  American Urological Association (AUA) annual meeting
- Place of Presentation
  San Diego (USA)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20145
[Presentation] MiR-200 family as EMT related microRNA in renal cell carcinoma2013
- Author(s)
  Yoshino Hirofumi
- Organizer
  米国癌学会
- Place of Presentation
  ワシントンDC
- Data Source
  KAKENHI-PROJECT-25861430
[]

1. ENOKIDA Hideki (80347103)

# of Collaborated Projects: 11 results

# of Collaborated Products: 42 results
2. NAKAGAWA Masayuki (90164144)

# of Collaborated Projects: 3 results

# of Collaborated Products: 10 results
3. MATSUSHITA Ryosuke (80735366)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
4. YONEMORI Masaya (00758013)

# of Collaborated Projects: 2 results

# of Collaborated Products: 18 results
5. 鑪野秀一 (30624655)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
6. 坂口大 (70779008)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
7. Miyamoto Kazutaka

# of Collaborated Projects: 2 results

# of Collaborated Products: 16 results
8. ITESAKO Toshihiko (10642613)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
9. YAMADA Yasutoshi (40437968)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 関直彦 (50345013)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
11. 大迫洋一 (60793354)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results

YOSHINO Hirofumi 吉野 裕史

吉野 裕史 ヨシノ ヒロフミ

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エクソソーム含有核酸の測定による尿路上皮癌の新規体液診断の開発Principal Investigator

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Targeting the Ubiquitin Proteasome Pathway as a Novel Therapeutic Strategy for Advanced Renal Cell CarcinomaPrincipal Investigator

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Development of the innovative treatment based on the search of microRNA blocking growth signals in urothelial carcinomaPrincipal Investigator

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治療抵抗性腎細胞癌の新規治療法開発に向けた機能性RNAネットワークの解明Principal Investigator

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[Journal Article] Characterization and treatment of gemcitabine‐ and cisplatin‐resistant bladder cancer cells with a pan‐RAS inhibitor2023

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[Journal Article] Potential therapeutic target secretogranin II might cooperate with hypoxia‐inducible factor 1α in sunitinib‐resistant renal cell carcinoma2023

YOSHINO Hirofumi 吉野裕史

吉野裕史ヨシノヒロフミ