Masuo Yusuke 増尾友佑

… Alternative Names

MASUO Yusuke 増尾友佑

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Researcher Number	90708140
Other IDs
External Links
Affiliation (Current)	2025: 金沢大学, 薬学系, 准教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 金沢大学, 薬学系, 准教授 2014 – 2020: 金沢大学, 薬学系, 助教
Review Section/Research Field	Principal Investigator Basic Section 47060:Clinical pharmacy-related / Medical pharmacy Except Principal Investigator Medium-sized Section 54:Internal medicine of the bio-information integration and related fields / Basic Section 08030:Family and consumer sciences, and culture and living-related / Medical pharmacy
Keywords	Principal Investigator 肝膜輸送体 / メタボロミクス / トランスポーター / アデノ随伴ウイルス / 薬物動態予測 / メタボローム解析 / 膜輸送体 / 薬物代謝酵素 / 尿毒素 / 慢性腎障害 … More / 機械学習 / AAV / 肝細胞 / MRP3 / BCRP / 排出輸送体 / 生体内基質 / バイオマーカー / 有機カチオン膜輸送体 / ヒトの薬物動態 / 薬物動態 / 薬物輸送担体 … More Except Principal Investigator 代謝 / 幹細胞 / 運動 / 胆汁酸 / メタボローム / 腸内細菌叢 / 野菜 / ナノファイバー / 薬物動態・代謝学 / 抗酸化物質 / 薬物治療 / 慢性臓器疾患 / 膜輸送体 / 薬物動態 Less

肝選択的ノックダウンによる肝排出膜輸送体の包括的かつ定量的な機能評価系の構築Principal Investigator
- Principal Investigator
  
  増尾友佑
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Kanazawa University
Lifestyle-related disease prevention effects of nanofiber technology-treated vegetables and clarification of their mechanism
- Principal Investigator
  
  長野隆男
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 08030:Family and consumer sciences, and culture and living-related
- Research Institution
  Ishikawa Prefectural University
Elucidation of molecular mechanisms of hematopoietic stem aging
- Principal Investigator
  
  平尾敦
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  Kanazawa University
Analysis of the transport of active metabolites by hepatic efflux transporters and identification of physiological substrates using machine learning-based metabolomicsPrincipal Investigator
- Principal Investigator
  
  Masuo Yusuke
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Kanazawa University
Searching for endogenous substrates of organic cation transporters by selective metabolomicsPrincipal Investigator
- Principal Investigator
  
  Masuo Yusuke
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Kanazawa University
Developments in estimation of the functional changes of transporters and drug metabolizing enzymes during renal failurePrincipal Investigator
- Principal Investigator
  
  Masuo Yusuke
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Kanazawa University
Inhibitory mechanisms of hepatic uptake transporters/OATP during renal failurePrincipal Investigator
- Principal Investigator
  
  MASUO YUSUKE
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Kanazawa University
Investigation of pathophysiological roles of transporter for antioxidant with an aim to develop pharmacotherapeutics of inflammatory organ diseases
- Principal Investigator
  
  Kato Yukio
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Kanazawa University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation

[Journal Article] L-type amino acid transporter 1 in hypothalamic neurons in mice maintains energy and bone homeostasis.2023
- Author(s)
  Park G, Fukasawa K, Horie T, Masuo Y, Inaba Y, Tatsuno T, Yamada T, Tokumura K, Iwahashi S, Iezaki T, Kaneda K, Kato Y, Ishigaki Y, Mieda M, Tanaka T, Ogawa K, Ochi H, Sato S, Shi YB, Inoue H, Lee H, Hinoi E.
- Journal Title
  
  JCI Insight
  
  Volume: 8 Issue: 7
- DOI
  10.1172/jci.insight.154925
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06688, KAKENHI-PROJECT-21K19556, KAKENHI-PROJECT-23K24455, KAKENHI-PROJECT-22K08660, KAKENHI-PROJECT-22K19545, KAKENHI-PROJECT-21K15350, KAKENHI-PROJECT-21H04865, KAKENHI-PROJECT-23K24764, KAKENHI-PROJECT-23K27996
[Journal Article] Adeno-associated virus-mediated knockdown demonstrates the major role of hepatic Bcrp in the overall disposition of the active metabolite of the tyrosine kinase inhibitor regorafenib in mice.2023
- Author(s)
  Al-Shammari AH, Masuo Y, Yoshino S, Yamashita R, Ishimoto T, Fujita K, Kato Y.
- Journal Title
  
  Drug Metab Pharmacokinet
  
  Volume: 49 Pages: 100483-100483
- DOI
  10.1016/j.dmpk.2022.100483
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06688, KAKENHI-PROJECT-19K07204, KAKENHI-PROJECT-23K24044, KAKENHI-PROJECT-20K15991
[Journal Article] A physiologically based pharmacokinetic and pharmacodynamic model for disposition of FF-10832.2022
- Author(s)
  Matsumoto T, Masuo Y, Tanaka A, Kimura T, Ioroi T, Yamakawa T, Kitahara H, Kato Y.
- Journal Title
  
  Int J Pharm
  
  Volume: 627 Pages: 122250-122250
- DOI
  10.1016/j.ijpharm.2022.122250
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06688
[Journal Article] Discrimination of hand-foot skin reaction caused by tyrosine kinase inhibitors based on direct keratinocyte toxicity and vascular endothelial growth factor receptor-2 inhibition2022
- Author(s)
  Hasan Alshammari A, Masuo Y, Fujita KI, Shimada K, Iida N, Wakayama T, Kato Y
- Journal Title
  
  Biochamical Pharmacology
  
  Volume: 印刷中 Pages: 114914-114914
- DOI
  10.1016/j.bcp.2022.114914
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07204, KAKENHI-PROJECT-21K06688
[Journal Article] Identification of Food-Derived Isoflavone Sulfates as Inhibition Markers for Intestinal Breast Cancer Resistance Proteins.2021
- Author(s)
  Agustina R, Masuo Y, Kido Y, Shinoda K, Ishimoto T, Kato Y
- Journal Title
  
  Drug Metab Dispos
  
  Volume: 49 Issue: 11 Pages: 972-984
- DOI
  10.1124/dmd.121.000534
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06688, KAKENHI-PROJECT-20K15991
[Journal Article] Effects of probenecid on hepatic and renal disposition of hexadecanedioate, an endogenous substrate of Organic anion transporting polypeptide 1b in rats.2021
- Author(s)
  Futatsugi A, Masuo Y, Kato Y
- Journal Title
  
  J Pharm Sci
  
  Volume: - Issue: 5 Pages: 2274-2284
- DOI
  10.1016/j.xphs.2021.02.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06745
[Journal Article] Chronic liver disease enables gut Enterococcus faecalis colonization to promote liver carcinogenesis2021
- Author(s)
  Iida Noriho、Mizukoshi Eishiro、Yamashita Tatsuya、Yutani Masahiro、Seishima Jun、Wang Ziyu、Arai Kuniaki、Okada Hikari、Yamashita Taro、Sakai Yoshio、Masuo Yusuke、Agustina Rina、Kato Yukio、Fujinaga Yukako、Oshima Masanobu、Honda Masao、Lebreton Fran?ois、Gilmore Michael S.、Kaneko Shuichi
- Journal Title
  
  Nature Cancer
  
  Volume: 2 Issue: 10 Pages: 1039-1054
- DOI
  10.1038/s43018-021-00251-3
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04823, KAKENHI-PROJECT-21K06688
[Journal Article] Oral Administration of the Food Derived Hydrophilic Antioxidant Ergothioneine Enhances Object Recognition Memory in Mice2020
- Author(s)
  Nakamichi N, Nakao S, Nishiyama M, Takeda Y, Ishimoto T, Masuo Y, Matsumoto S, Suzuki M, Kato Y.
- Journal Title
  
  Curr Mol Pharmacol
  
  Volume: - Issue: 2 Pages: 220-233
- DOI
  10.2174/1874467213666200212102710
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06745, KAKENHI-PROJECT-19K23797, KAKENHI-PROJECT-19K07126, KAKENHI-PROJECT-20K15991
[Journal Article] 6-Hydroxyindole is an endogenous long-lasting OATP1B1 inhibitor elevated in renal failure patients2020
- Author(s)
  Masuo Yusuke、Fujita Ken-ichi、Mishiro Kenji、Seba Natsumi、Kogi Tatsuya、Okumura Hidenori、Matsumoto Natsumi、Kunishima Munetaka、Kato Yukio
- Journal Title
  
  Drug Metabolism and Pharmacokinetics
  
  Volume: 35 Issue: 6 Pages: 555-562
- DOI
  10.1016/j.dmpk.2020.09.001
- NAID
  50014656616
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02584, KAKENHI-PROJECT-18K06745
[Journal Article] Higher Systemic Exposure to Unbound Active Metabolites of Regorafenib Is Associated With Short Progression-Free Survival in Colorectal Cancer Patients.2020
- Author(s)
  Kubota Y, Fujita KI, Takahashi T, Sunakawa Y, Ishida H, Hamada K, Ichikawa W, Tsunoda T, Shimada K, Masuo Y, Kato Y, Sasaki Y.
- Journal Title
  
  Clin Pharmacol Ther
  
  Volume: - Issue: 3 Pages: 586-595
- DOI
  10.1002/cpt.1810
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06745, KAKENHI-PROJECT-19K07204, KAKENHI-PROJECT-18H02584
[Journal Article] Static Model?Based Assessment of OATP1B1-Mediated Drug Interactions with Preincubation-Dependent Inhibitors Based on Inactivation and Recovery Kinetics2020
- Author(s)
  Taguchi Takayuki、Masuo Yusuke、Futatsugi Azusa、Kato Yukio
- Journal Title
  
  Drug Metabolism and Disposition
  
  Volume: 48 Issue: 9 Pages: 750-758
- DOI
  10.1124/dmd.120.000020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02584, KAKENHI-PROJECT-18K06745
[Journal Article] Homostachydrine is a Xenobiotic Substrate of OCTN1/SLC22A4 and Potentially Sensitizes Pentylenetetrazole-Induced Seizures in Mice2020
- Author(s)
  Nishiyama Misa、Nakamichi Noritaka、Yoshimura Tomoyuki、Masuo Yusuke、Komori Tomoe、Ishimoto Takahiro、Matsuo Jun-ichi、Kato Yukio
- Journal Title
  
  Neurochemical Research
  
  Volume: 45 Issue: 11 Pages: 2664-2678
- DOI
  10.1007/s11064-020-03118-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07126, KAKENHI-PROJECT-20K15991, KAKENHI-PROJECT-18H02584, KAKENHI-PROJECT-18K06745, KAKENHI-PROJECT-19K23797
[Journal Article] Hydrolyzed Salmon Milt Extract Enhances Object Recognition and Location Memory Through an Increase in Hippocampal Cytidine Nucleoside Levels in Normal Mice2019
- Author(s)
  Nakamichi Noritaka、Nakao Shunsuke、Masuo Yusuke、Koike Ayaka、Matsumura Naoto、Nishiyama Misa、Al-Shammari Aya Hasan、Sekiguchi Hirotaka、Sutoh Keita、Usumi Koji、Kato Yukio
- Journal Title
  
  Journal of Medicinal Food
  
  Volume: 22 Issue: 4 Pages: 408-415
- DOI
  10.1089/jmf.2018.4285
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19482, KAKENHI-PROJECT-18K06745, KAKENHI-PROJECT-19K07126
[Journal Article] Ergothioneine-induced neuronal differentiation is mediated through activation of S6K1 and neurotrophin 4/5-TrkB signaling in murine neural stem cells2019
- Author(s)
  Ishimoto T, Masuo Y, Kato Y, Nakamichi N
- Journal Title
  
  Cell Signal.
  
  Volume: 53 Pages: 269-280
- DOI
  10.1016/j.cellsig.2018.10.012
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06745, KAKENHI-PROJECT-16K08266
[Journal Article] Metabolome Analysis Reveals Dermal Histamine Accumulation in Murine Dermatitis Provoked by Genetic Deletion of P-Glycoprotein and Breast Cancer Resistance Protein2019
- Author(s)
  Hashimoto N, Nakamichi N, Nanmo H, Kimura KI, Masuo Y, Sakai Y, Schinkel AH, Sato S, Soga T, Kato Y
- Journal Title
  
  Pharm Res
  
  Volume: 36 Issue: 11 Pages: 158-158
- DOI
  10.1007/s11095-019-2695-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06745, KAKENHI-PROJECT-19K07126, KAKENHI-PROJECT-18H02584
[Journal Article] Maturational Characterization of Mouse Cortical Neurons Three-Dimensionally Cultured in Functional Polymer FP001-Containing Medium2019
- Author(s)
  Nakamichi N, Matsumoto Y, Kawanishi T, Ishimoto T, Masuo Y, Horikawa M, Kato Y
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 42 Issue: 9 Pages: 1545-1553
- DOI
  10.1248/bpb.b19-00307
- NAID
  130007700083
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2019-09-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06745, KAKENHI-PROJECT-19K07126, KAKENHI-PROJECT-19K23797, KAKENHI-PROJECT-18H02584
[Journal Article] Short-lasting Inhibition of Hepatic Uptake Transporter OATP1B1 by Tyrosine Kinase Inhibitor Pazopanib2019
- Author(s)
  Taguchi T, Masuo Y, Sakai Y, Kato Y.
- Journal Title
  
  Drug Metab Pharmacokinet
  
  Volume: 34 Issue: 6 Pages: 372-379
- DOI
  10.1016/j.dmpk.2019.08.001
- NAID
  50014558527
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06745, KAKENHI-PROJECT-18H02584
[Journal Article] Influx and efflux transporters contribute to the increased dermal exposure to active metabolite of regorafenib after repeated oral administration2019
- Author(s)
  Al-Shammari AH, Masuo Y, Fujita K, Yoshikawa Y, Nakamichi N, Kubota Y, Sasaki Y, Kato Y
- Journal Title
  
  J Pharm Sci.
  
  Volume: 印刷中 Issue: 6 Pages: 2173-2179
- DOI
  10.1016/j.xphs.2019.01.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06745, KAKENHI-PROJECT-18H02584, KAKENHI-PROJECT-19K07126
[Journal Article] Pazopanib Interacts With Irinotecan by Inhibiting UGT1A1-mediated Glucuronidation, but Not OATP1B1-mediated Hepatic Uptake, of an Active Metabolite SN-382019
- Author(s)
  Iwase M, Fujita KI, Nishimura Y, Seba N, Masuo Y, Ishida H, Kato Y, Kiuchi Y
- Journal Title
  
  Cancer Chemother Pharmacol.
  
  Volume: 83 Issue: 5 Pages: 993-998
- DOI
  10.1007/s00280-019-03784-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06745, KAKENHI-PROJECT-16K08918
[Journal Article] Bile Duct Obstruction Leads to Increased Intestinal Expression of Breast Cancer Resistance Protein With Reduced Gastrointestinal Absorption of Imatinib.2019
- Author(s)
  Kawanishi T, Arakawa H, Masuo Y, Nakamichi N, Kato Y
- Journal Title
  
  J Pharm Sci
  
  Volume: 108 Issue: 9 Pages: 3130-3137
- DOI
  10.1016/j.xphs.2019.05.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06745, KAKENHI-PROJECT-19K07126, KAKENHI-PROJECT-18H02584
[Journal Article] Combination Metabolomics Approach for Identifying Endogenous Substrates of Carnitine/Organic Cation Transporter OCTN12018
- Author(s)
  Masuo Y, Ohba Y, Yamada K, Al-Shammari AH, Seba N, Nakamichi N, Ogihara T, Kunishima M, Kato Y
- Journal Title
  
  Pharm Res.
  
  Volume: 35 Issue: 11 Pages: 224-224
- DOI
  10.1007/s11095-018-2507-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06745, KAKENHI-PROJECT-18H02584, KAKENHI-PROJECT-16K08266
[Journal Article] P-Glycoprotein in skin contributes to transdermal absorption of topical corticosteroids.2017
- Author(s)
  Hashimoto N, Nakamichi N, Yamazaki E, Oikawa M, Masuo Y, Schinkel AH, Kato Y.
- Journal Title
  
  Int J Pharm
  
  Volume: 521 Issue: 1-2 Pages: 365-373
- DOI
  10.1016/j.ijpharm.2017.02.064
- NAID
  120006306245
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04664, KAKENHI-PROJECT-16K18934, KAKENHI-PROJECT-16K08266
[Journal Article] Utilization of Liver Microsomes to Estimate Hepatic Intrinsic Clearance of Monoamine Oxidase Substrate Drugs in Humans.2017
- Author(s)
  Masuo Y, Nagamori S, Hasegawa A, Hayashi K, Isozumi N, Nakamichi N, Kanai Y, Kato Y.
- Journal Title
  
  Pharm Res
  
  Volume: 印刷中 Issue: 6 Pages: 1233-1243
- DOI
  10.1007/s11095-017-2140-4
- NAID
  120006306246
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04664, KAKENHI-PROJECT-15H04685, KAKENHI-PROJECT-15K15053, KAKENHI-PROJECT-16K18934, KAKENHI-PROJECT-16K08266, KAKENHI-PROJECT-17H04190, KAKENHI-PROJECT-15K08274
[Journal Article] Organic Cation Transporter 1 Is Responsible for Hepatocellular Uptake of the Tyrosine Kinase Inhibitor Pazopanib2017
- Author(s)
  Ellawatty Waleed Elsayed Ahmed、Masuo Yusuke、Fujita Ken-ichi、Yamazaki Erina、Ishida Hiroo、Arakawa Hiroshi、Nakamichi Noritaka、Abdelwahed Ramadan、Sasaki Yasutsuna、Kato Yukio
- Journal Title
  
  Drug Metab Dispos
  
  Volume: 46 Issue: 1 Pages: 33-40
- DOI
  10.1124/dmd.117.076554
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08266, KAKENHI-PROJECT-16K18934
[Journal Article] Involvement of the Transporters P-Glycoprotein and Breast Cancer Resistance Protein in Dermal Distribution of the Multikinase Inhibitor Regorafenib and Its Active Metabolites2017
- Author(s)
  Fujita Ken-ichi、Masuo Yusuke、Yamazaki Erina、Shibutani Toshiki、Kubota Yutaro、Nakamichi Noritaka、Sasaki Yasutsuna、Kato Yukio
- Journal Title
  
  J Pharm Sci
  
  Volume: 106 Issue: 9 Pages: 2632-2641
- DOI
  10.1016/j.xphs.2017.04.064
- NAID
  120006336017
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08266, KAKENHI-PROJECT-15H04664, KAKENHI-PROJECT-16K18934
[Journal Article] Farnesoid X Receptor Protects Against Low-Dose Carbon Tetrachloride-Induced Liver Injury Through the Taurocholate-JNK Pathway.2017
- Author(s)
  Takahashi S, Tanaka N, Golla S, Fukami T, Krausz KW, Polunas MA, Weig BC, Masuo Y, Xie C, Jiang C, Gonzalez FJ.
- Journal Title
  
  Toxicol Sci.
  
  Volume: 158 Issue: 2 Pages: 334-346
- DOI
  10.1093/toxsci/kfx094
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18934
[Journal Article] Carnitine/Organic Cation Transporter OCTN1 Negatively Regulates Activation in Murine Cultured Microglial Cells2017
- Author(s)
  Ishimoto Takahiro、Nakamichi Noritaka、Nishijima Hikari、Masuo Yusuke、Kato Yukio
- Journal Title
  
  Neurochem Res
  
  Volume: 43 Issue: 1 Pages: 107-119
- DOI
  10.1007/s11064-017-2350-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08266, KAKENHI-PROJECT-15H04664, KAKENHI-PROJECT-16K18934
[Journal Article] Characterization of long-lasting Oatp inhibition by typical inhibitor cyclosporine A and in vitro-in vivo discrepancy in its drug interaction potential in rats.2016
- Author(s)
  Taguchi T, Masuo Y, Kogi T, Nakamichi N, Kato Y
- Journal Title
  
  J Pharm Sci
  
  Volume: 105 Issue: 7 Pages: 2231-2239
- DOI
  10.1016/j.xphs.2016.04.025
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04664, KAKENHI-PROJECT-16K08266, KAKENHI-PROJECT-16K18934
[Journal Article] Cyp2c70 is responsible for the species difference in bile acid metabolism between mice and humans2016
- Author(s)
  Takahashi S, Fukami T, Masuo Y, Brocker CN, Xie C, Krausz KW, C. Wolf CR, Henderson CJ, Gonzalez FJ
- Journal Title
  
  J. Lipid Res.
  
  Volume: 57 Issue: 12 Pages: 2130-2137
- DOI
  10.1194/jlr.m071183
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18934
[Journal Article] L503F variant of carnitine/organic cation transporter 1 efficiently transports metformin and other biguanides.2016
- Author(s)
  Futatsugi A, Masuo Y, Kawabata S, Nakamichi N, Kato Y.
- Journal Title
  
  J Pharm Pharmacol
  
  Volume: 68 Issue: 9 Pages: 1160-1169
- DOI
  10.1111/jphp.12574
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04664, KAKENHI-PROJECT-16K08266, KAKENHI-PROJECT-16K18934
[Journal Article] Localizatoin of xenobiotic transporter OCTN1/SLC22A4 in hepatic stellate cells and its protective role in liver fibrosis.2016
- Author(s)
  Tang Y, Masuo Y, Sakai Y, Wakayama T, Sugiura T, Harada R, Futatsugi A, Komura T, Nakamichi N, Sekiguchi H, Sutoh K, Usumi K, Iseki S, Kaneko S, Kato Y.
- Journal Title
  
  J Pharm Sci
  
  Volume: 印刷中 Issue: 5 Pages: 1779-89
- DOI
  10.1016/j.xphs.2016.02.023
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04664, KAKENHI-PROJECT-25460092, KAKENHI-PROJECT-26860099, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-16K08266
[Journal Article] Screening to Identify Multidrug Resistance-Associated Protein Inhibitors with Neuroblastoma-Selective Cytotoxicity2016
- Author(s)
  Nakamichi N, Ishimoto T, Yamauchi Y, Masuo Y, Kato Y.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 39 Issue: 10 Pages: 1638-1645
- DOI
  10.1248/bpb.b16-00319
- NAID
  130005598491
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04664, KAKENHI-PROJECT-16K08266, KAKENHI-PROJECT-16K18934
[Journal Article] Increased plasma concentrations of unbound SN-38, the active metabolite of irinotecan, in cancer patients with severe renal failure2016
- Author(s)
  Ken-ichi Fujita, Yusuke Masuo, Hidenori Okumura, Yusuke Watanabe, Hiromichi Suzuki, Yu Sunakawa, Ken Shimada, Kaori Kawara, Yuko Akiyama, Masanori Kitamura, Munetaka Kunishima, Yasutsuna Sasaki, Yukio Kato
- Journal Title
  
  Pharmaceutical Research
  
  Volume: 33 Issue: 2 Pages: 269-282
- DOI
  10.1007/s11095-015-1785-0
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460205, KAKENHI-PROJECT-15H04664, KAKENHI-PROJECT-26860099
[Journal Article] Organic cation transporter Octn1-mediated uptake of food-derived antioxidant ergothioneine into infiltrating macrophages during intestinal inflammation in mice.2015
- Author(s)
  Shimizu T, Masuo Y, Takahashi S, Nakamichi N and Kato Y.
- Journal Title
  
  Drug Metab Pharmacokinet（印刷中）
  
  Volume: （印刷中）
- NAID
  50014429956
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390040
[Journal Article] Gene ablation of carnitine/organic cation transporter 1 reduces gastrointestinal absorption of 5-aminosalicylate in mice.2015
- Author(s)
  Shimizu T, Kijima A, Masuo Y, Ishimoto T, Sugiura T, Takahashi S, Nakamichi N, Kato Y.
- Journal Title
  
  Chem Pharm Bull
  
  Volume: （印刷中）
- NAID
  130005068086
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390040
[Journal Article] Organic cation transporter-mediated ergothioneine uptake in mouse neural progenitor cells suppresses proliferation and promotes differentiation into neurons2014
- Author(s)
  IshimotoT, Nakamichi N, Hosotani H, Masuo Y, Sugiura T and Kato Y.
- Journal Title
  
  PLoS One
  
  Volume: 9(2) Issue: 2 Pages: e89434-e89434
- DOI
  10.1371/journal.pone.0089434
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390040, KAKENHI-PROJECT-25460092
[Journal Article] Interaction of Novel Platelet-increasing Agent Eltrombopag with Rosuvastatin via Breast Cancer Resistance Protein in Human2014
- Author(s)
  Takeuchi, et al.
- Journal Title
  
  Drug Metabolism and Disposition
  
  Volume: 42 Issue: 4 Pages: 726-734
- DOI
  10.1124/dmd.113.054767
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J04561, KAKENHI-PROJECT-24390040, KAKENHI-PROJECT-25460092
[Presentation] アデノ随伴ウイルスを用いた肝選択的遺伝子デリバリーによる排出膜輸送体Mrp3の機能評価2024
- Author(s)
  佐竹聖真、増尾友佑、吉野将太郎、加藤将夫
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-21K06688
[Presentation] Identification of physiological substrates of transporters by structure-selective metabolomics2023
- Author(s)
  Yusuke Masuo
- Organizer
  日本薬物動態学会第38回年会／第23回シトクロムP450国際会議国際合同大会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06688
[Presentation] Involvement of BCRP and other efflux transporters in pharmacokinetics of pazopanib in mice2023
- Author(s)
  Ruth Shekina Lumumba, Yusuke Masuo, Shotaro Yoshino, Ken-ichi Fujita, Yukio Kato
- Organizer
  日本薬物動態学会第38回年会／第23回シトクロムP450国際会議国際合同大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06688
[Presentation] AAVによる遺伝子送達を利用した肝BCRPの機能評価とメタボロミクス解析2023
- Author(s)
  増尾友佑、吉野将太郎、山下怜矢、藤田健一、加藤将夫
- Organizer
  第44回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-21K06688
[Presentation] メタボロミクスによるOATP1BとCYP3Aの活性変化を同時に評価できる生体内基質探索2023
- Author(s)
  山本貴仁、増尾友佑、加藤将夫
- Organizer
  日本薬剤学会第38年会
- Data Source
  KAKENHI-PROJECT-21K06688
[Presentation] Investigation of the role of human hepatic Bcrp by using adeno-associated virus mediated gene delivery2023
- Author(s)
  Shotaro Yoshino, Yusuke Masuo, Reiya Yamashita, Ken-ichi Fujita, Yukio Kato
- Organizer
  日本薬物動態学会第38回年会／第23回シトクロムP450国際会議国際合同大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06688
[Presentation] レンバチニブ投与患者血漿検体のメタボロミクス解析による薬効バイオマーカー探索2022
- Author(s)
  水戸守智香、増尾友佑、荒井潤、松本奈都美、鈴木康介、吉田仁、藤田健一、加藤将夫
- Organizer
  第96回日本薬理学会年会・第43回日本臨床薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-21K06688
[Presentation] 構造選択的メタボロミクスによる膜輸送体の生体内基質同定2022
- Author(s)
  増尾友佑
- Organizer
  日本薬学会北陸支部第134回例会
- Invited
- Data Source
  KAKENHI-PROJECT-21K06688
[Presentation] アンターゲットメタボロミクスによる膜輸送体BCRPバイオマーカーの探索2022
- Author(s)
  増尾友佑、Rina Agustina、加藤将夫
- Organizer
  第16回メタボロームシンポジウム
- Data Source
  KAKENHI-PROJECT-21K06688
[Presentation] アデノ随伴ウィルスによる肝選択的ノックダウンによる肝BCRPの機能評価2022
- Author(s)
  増尾友佑、吉野将太郎、Alshammari Aya、山下怜矢、石本尚大、加藤将夫
- Organizer
  日本薬剤学会第37年会
- Data Source
  KAKENHI-PROJECT-21K06688
[Presentation] 生体内化合物の臓器ハンドリング解明を目指した動静脈アンターゲットメタボロミクス2022
- Author(s)
  須崎智子、増尾友佑、及川夏月、加藤将夫
- Organizer
  日本薬物動態学会第37回年会
- Data Source
  KAKENHI-PROJECT-21K06688
[Presentation] 食餌由来高分子核酸の小腸膜透過と循環血への吸収性の構造特性に基づいた比較2022
- Author(s)
  増尾友佑、西澤友希、桐山恵介、藤田美華、須藤慶太、加藤将夫
- Organizer
  日本薬物動態学会第37回年会
- Data Source
  KAKENHI-PROJECT-21K06688
[Presentation] 有効腎血漿流量の評価に応用可能な生体内化合物の網羅的探索2021
- Author(s)
  及川夏月、増尾友佑、三代憲司、国嶋崇隆、加藤将夫
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-18K06745
[Presentation] マルチキナーゼ阻害薬pazopanibの消化管吸収と胆汁排泄に及ぼすBCRP/ABCG2の関与2021
- Author(s)
  吉野将太郎、増尾友佑、加藤将夫
- Organizer
  日本薬物動態学会第36回年会
- Data Source
  KAKENHI-PROJECT-21K06688
[Presentation] Isoflavone Sulfates Conjugates as Potential Physiological Substrates of BCRP for Estimation of in vivo Inhibition.2021
- Author(s)
  Rina Agustina, Yusuke Masuo, Kyosuke Shinoda, Shinji Mima, Masahiko Ito, Yukio Kato
- Organizer
  EB (Experimental Biology)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06688
[Presentation] アンターゲットメタボロミクスによるBCRPバイオマーカーとしてのイソフラボン硫酸抱合体の同定2021
- Author(s)
  増尾友佑、Rina Agustina、笹田京佑、美馬伸治、伊藤匡彦、加藤将夫
- Organizer
  日本薬物動態学会第36回年会
- Data Source
  KAKENHI-PROJECT-21K06688
[Presentation] ゲムシタビンによる赤血球毒性に及ぼす膜輸送体OCTN1の関与2021
- Author(s)
  増尾友佑、田中杏奈、加藤将夫
- Organizer
  日本薬剤学会第36年会
- Data Source
  KAKENHI-PROJECT-21K06688
[Presentation] 高分子DNAはpyrimidine nucleosideとして消化管吸収される2020
- Author(s)
  増尾友佑、小池彩花、石本尚大、加藤将夫
- Organizer
  日本薬剤学会第35年会
- Data Source
  KAKENHI-PROJECT-18K06745
[Presentation] Association between pharmacokinetics and dermal toxicology of tyrosine kinase inhibitors in a mouse model2020
- Author(s)
  アルシャッマリアヤ、増尾友佑、島田和弘、藤田健一、若山友彦、加藤将夫
- Organizer
  第35回日本薬物動態学会年会
- Data Source
  KAKENHI-PROJECT-18K06745
[Presentation] チロシンキナーゼ阻害薬による手足症候群と表皮角化細胞への毒性との関連2020
- Author(s)
  増尾友佑、島田和弘、石本尚大、加藤将夫
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-18K06745
[Presentation] Screening of endogenous OCTs substrates applicable for prediction of drug interactions2019
- Author(s)
  Yusuke Masuo, Megumi Kato, Shiori Komura, Takahiro Ishimoto, Yukio Kato
- Organizer
  12th International ISSX Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06745
[Presentation] 妊娠高血圧症候群治療への応用を目指したヒトaminopeptidase A組換えタンパク質の体内動態解析2019
- Author(s)
  近藤友美、増尾友佑、今村龍、水谷栄彦、松本邦夫、加藤将夫
- Organizer
  第24回日本病態プロテアーゼ学会学術集会
- Data Source
  KAKENHI-PROJECT-18K06745
[Presentation] マウス単離骨髄細胞へのゲムシタビン取り込み機構の解析2019
- Author(s)
  田中杏奈、増尾友佑、松本建、加藤将夫
- Organizer
  日本薬剤学会第34年会
- Data Source
  KAKENHI-PROJECT-18K06745
[Presentation] BCRPのin vivoでの輸送機能評価に適用可能なBCRP生体内基質の網羅的探索2019
- Author(s)
  笹田京佑、増尾友佑、石本尚大、加藤将夫
- Organizer
  日本薬物動態学会第34回年会
- Data Source
  KAKENHI-PROJECT-18K06745
[Presentation] BCRP細胞外領域に対する抗体作製を目指したBCRP発現系の最適化2019
- Author(s)
  森永真理恵、増尾友佑、石本尚大、鎌田春彦、加藤将夫
- Organizer
  日本薬物動態学会第34回年会
- Data Source
  KAKENHI-PROJECT-18K06745
[Presentation] チロシンキナーゼ阻害薬による手足症候群の発症機構：表皮角化細胞への毒性との関連2019
- Author(s)
  島田和弘、増尾友佑、藤田健一、加藤将夫
- Organizer
  第41回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-18K06745
[Presentation] チロシンキナーゼ阻害薬のケラチノサイトにおける分布・毒性と皮膚障害との関連2019
- Author(s)
  増尾友佑、加藤将夫
- Organizer
  日本薬物動態学会第34回年会
- Invited
- Data Source
  KAKENHI-PROJECT-18K06745
[Presentation] Identification of endogenous substrates of gastrointestinal inflammation-associated transporters, OCTN1/SLC22A42019
- Author(s)
  Yusuke Masuo, Yukio Kato
- Organizer
  The 27th Annual Meeting of The Korean Society of Applied Pharmacology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06745
[Presentation] 膜輸送体OCTsのin vivoでの機能評価を目指した内因性基質の網羅的探索2019
- Author(s)
  増尾友佑、加藤愛、石本尚大、加藤将夫
- Organizer
  第14回トランスポーター研究会年会
- Data Source
  KAKENHI-PROJECT-18K06745
[Presentation] Optimization of the preincubation period for assessment of OATP1B1 inhibition by preincubation-dependent inhibitors2018
- Author(s)
  Takayuki Taguchi, Yusuke Masuo, Yoshiyuki Sakai, Yukio Kato
- Organizer
  日本薬物動態学会第33回年会・MDO国際合同学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06745
[Presentation] SLC22A4の生体内基質探索：基質認識特性に基づいた構造選択的メタボロミクスによるアプローチ2018
- Author(s)
  増尾友佑、加藤将夫
- Organizer
  第13回トランスポーター研究会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18K06745
[Presentation] Cytotoxic effects of tyrosine kinase inhibitors in keratinocytes and their possible relevance to ABC transporters2018
- Author(s)
  Kazuhiro Shimada, Yusuke Masuo, Ken-ichi Fujita, Yasutsuna Sasaki, Yukio Kato
- Organizer
  日本薬物動態学会第33回年会・MDO国際合同学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06745
[Presentation] Comparison of Intestinal Absorption of Nucleic Acids: Comprehensive Quantification-based Analysis using Mass Spectrometry2018
- Author(s)
  Yusuke Masuo, Ayaka Koike, Yukio Kato
- Organizer
  日本薬物動態学会第33回年会・MDO国際合同学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06745
[Presentation] 遺伝子欠損マウス臓器を基質源としたメタボローム解析による膜輸送体BCRPの生体内基質探索2018
- Author(s)
  笹田京佑、増尾友佑、中道範隆、加藤将夫
- Organizer
  日本薬学会北陸支部第130回例会
- Data Source
  KAKENHI-PROJECT-18K06745
[Presentation] Screening of endogenous OCTs substrates based on in vivo inhibition studies to estimate drug interaction potential2018
- Author(s)
  Megumi Kato, Yusuke Masuo, Yukio Kato
- Organizer
  日本薬物動態学会第33回年会・MDO国際合同学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06745
[Presentation] Construction of neutralizing antibodies against P-glycoprotein by using antibody phage displays2018
- Author(s)
  Marie Morinaga, Yusuke Masuo, Takahiro Ishimoto, Noritaka Nakamichi, Haruhiko Kamada, Yukio Kato
- Organizer
  日本薬物動態学会第33回年会・MDO国際合同学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06745
[Presentation] Accumulation of active metabolite of anticancer agent regorafenib involves nonlinear hepatic distribution after repeated dose2018
- Author(s)
  Aya Hasan, Yusuke Masuo, Ken-ichi Fujita, Yutaro Kubota, Yasutsuna Sasaki, and Yukio Kato
- Organizer
  日本薬物動態学会第33回年会・MDO国際合同学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06745
[Presentation] Identification of Endogenous Substrates of SLC22A4 by Metabolomic Approach Based on Transporter and Structure Selective Strategies2018
- Author(s)
  Yusuke Masuo, Yuri Ohba, Kohei Yamada, Noritaka Nakamichi, Munetaka Kunishima, Yukio Kato
- Organizer
  PharmSci 360 American Association of Pharmaceutical Scientists
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06745
[Presentation] Characterization of effect of rifampicin on disposition of endogenous OATPs substrates in rats2018
- Author(s)
  Azusa Futatsugi, Yusuke Masuo, Yukio Kato
- Organizer
  日本薬物動態学会第33回年会・MDO国際合同学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06745
[Presentation] 構造選択的メタボロミクスによる疾患関連輸送体OCTN1の生体内基質探索2017
- Author(s)
  増尾友佑、大庭悠里、山田耕平、中道範隆、国嶋崇隆、加藤将夫
- Organizer
  第12回トランスポーター研究会年会
- Data Source
  KAKENHI-PROJECT-16K18934
[Presentation] 輸送機能と基質認識特性を利用したメタボロミクスによるSLC22A4生体内基質探索2017
- Author(s)
  増尾友佑、大庭悠里、山田耕平、中道範隆、国嶋崇隆、加藤将夫
- Organizer
  日本薬剤学会第32年会
- Data Source
  KAKENHI-PROJECT-16K18934
[Presentation] Identification of endogenous BCRP substrate by metabolomics using gene knockout mice and transporter expressing system2017
- Author(s)
  笹田京佑、増尾友佑、中道範隆、加藤将夫
- Organizer
  日本薬物動態学会第32回年会
- Data Source
  KAKENHI-PROJECT-16K18934
[Presentation] Involvement of ABC drug transporters in disposition of tyrosine kinase inhibitor regorafenib and its active metabolites after repeated oral dose2017
- Author(s)
  Aya Hasan、増尾友佑、藤田健一、山﨑絵里名、久保田祐太郎、中道範隆、佐々木康綱、加藤将夫
- Organizer
  日本薬物動態学会第32回年会
- Data Source
  KAKENHI-PROJECT-16K18934
[Presentation] 誘導体化を利用した構造選択的メタボロミクスによる有機カチオン膜輸送体の基質探索2017
- Author(s)
  増尾友佑、山田耕平、中道範隆、国嶋崇隆、加藤将夫
- Organizer
  第39回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-16K18934
[Presentation] Screening of Endogenous Substrates of SLC22A4 by Metabolomic Approach Based on Transporting Activity and Substrate Recognition2017
- Author(s)
  増尾友佑、中道範隆、加藤将夫
- Organizer
  日本薬物動態学会第32回年会
- Data Source
  KAKENHI-PROJECT-16K18934
[Presentation] モノ核酸関連化合物の網羅的定量による消化管吸収評価2017
- Author(s)
  小池彩花、増尾友佑、中道範隆、加藤将夫
- Organizer
  日本薬学会北陸支部第129回例会
- Data Source
  KAKENHI-PROJECT-16K18934
[Presentation] モノ核酸化合物の網羅的定量による消管吸収性比較2017
- Author(s)
  増尾友佑、小池彩花、中道範隆、加藤将夫
- Organizer
  第11回メタボロームシンポジウム
- Data Source
  KAKENHI-PROJECT-16K18934
[Presentation] Characterization of OATP1B1 inhibition by indole metabolites2017
- Author(s)
  清波夏実、増尾友佑、藤田健一、中道範隆、佐々木康綱、加藤将夫
- Organizer
  日本薬物動態学会第32回年会
- Data Source
  KAKENHI-PROJECT-16K18934
[Presentation] Keratinocyte における膜輸送体の発現とレゴラフェニブ分布に及ぼす影響2017
- Author(s)
  島田和弘、増尾友佑、藤田健一、山﨑絵里名、久保田祐太朗、中道範隆、佐々木康綱、加藤将夫
- Organizer
  日本薬学会北陸支部第129回例会
- Data Source
  KAKENHI-PROJECT-16K18934
[Presentation] Involvement of ABC drug transporters in disposition of active metabolites of tyrosine kinase inhibitor Regorafenib2016
- Author(s)
  Yamazaki E, Masuo Y, Fujita K, Shibutani T, Nakamichi N, Sasaki Y, Kato Y
- Organizer
  日本薬物動態学会第31回年会
- Place of Presentation
  松本
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-16K18934
[Presentation] Possible oxidative metabolism in the body of ergothioneine, a food-derived substrate of Crohn's disease-associated transporter OCTN1/SLC22A42016
- Author(s)
  Ainaka R, Masuo Y, Yoshimura T, Nakamichi N, Matsuo J, Kato Y
- Organizer
  日本薬物動態学会第31回年会
- Place of Presentation
  松本
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-16K18934
[Presentation] Proteomics-based validation of in vitro-in vivo extrapolation using liver microsomes to predict intrinsic clearance of MAO substrates2016
- Author(s)
  Hasegawa A, Masuo Y, Nagamori S, Hayashi K, Nakamichi N, Kanai Y, Kato Y
- Organizer
  日本薬物動態学会第31回年会
- Place of Presentation
  松本
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-16K18934
[Presentation] Functional characterization of OCTN1-mediated creatinine transport2016
- Author(s)
  Masuo Y, Takemura H, Matsuo M, Nakamichi N, Kato Y
- Organizer
  日本薬物動態学会第31回年会
- Place of Presentation
  松本
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-16K18934
[Presentation] 臓器障害関連抗酸化物質Ergothioneineの生体内代謝物探索2016
- Author(s)
  増尾友佑、荒川大、中道範隆、加藤将夫
- Organizer
  第10回メタボロームシンポジウム
- Place of Presentation
  鶴岡
- Year and Date
  2016-10-19
- Data Source
  KAKENHI-PROJECT-16K18934
[Presentation] 構造選択的メタボロームによる膜輸送体OCTN1の生体内基質探索2016
- Author(s)
  大庭悠里、増尾友佑、山田耕平、中道範隆、国嶋崇隆、加藤将夫
- Organizer
  第10回メタボロームシンポジウム
- Place of Presentation
  鶴岡
- Year and Date
  2016-10-19
- Data Source
  KAKENHI-PROJECT-16K18934
[Presentation] Identification of endogenous OCTN1 substrates by transporter/structure selective-metabolome approach2016
- Author(s)
  Ohba Y, Masuo Y, Yamada K, Nakamichi N, Kunishima N, Kato Y
- Organizer
  日本薬物動態学会第31回年会
- Place of Presentation
  松本
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-16K18934
[Presentation] Inhibition of human hepatic transporter OATP1B1 by indole metabolites2016
- Author(s)
  Seba N, Masuo Y, Fujita K, Nakamichi N, Sasaki Y, Kato Y
- Organizer
  日本薬物動態学会第31回年会
- Place of Presentation
  松本
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-16K18934
[Presentation] Mechanistic analysis of long-lasting OATP inhibition by cyclosporine A2016
- Author(s)
  Taguchi T, Masuo Y, Nakamichi N, Kato Y
- Organizer
  日本薬物動態学会第31回年会
- Place of Presentation
  松本
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-16K18934
[Presentation] Roles of hepatic BCRP and P-gP in pharmacokinetics of regorafenib and active metabolites M-2 and M-52016
- Author(s)
  Fujita K, Masuo Y, Kubota Y, Sasaki Y, Kato Y
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16K18934
[Presentation] レゴラフェニブと活性代謝物の体内動態解析とABC輸送担体の関与2016
- Author(s)
  藤田健一、増尾友佑、山崎絵里名、澁谷俊紀、中道範隆、佐々木康綱、加藤将夫
- Organizer
  第37回日本臨床薬理学会学術総会
- Place of Presentation
  米子
- Year and Date
  2016-12-01
- Data Source
  KAKENHI-PROJECT-16K18934
[Presentation] Evaluation of in vitro-in vivo extrapolation strategy using liver microsomes to predict intrinsic clearance of MAO substrates in humans2016
- Author(s)
  Masuo Y, Nagamori S, Hayashi K, Hasegawa A, Nakamichi N, Kanai Y, Kato Y
- Organizer
  20th Microsomes and Drug Oxidations
- Place of Presentation
  Davis, USA
- Year and Date
  2016-10-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18934
[Presentation] Functional Expression of Carnitine/organic Cation Transporter OCTN1/SLC22A4 in Hepatic Stellate Cell2015
- Author(s)
  Tang Y, Masuo Y, Nakamichi N, Kato Y:
- Organizer
  2015 AAPS Annual Meeting and Exposition
- Place of Presentation
  Orlando, USA
- Year and Date
  2015-10-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860099
[Presentation] 内因性尿毒症物質インドキシル硫酸によるOATP1B1のlong-lasting inhibition2015
- Author(s)
  小木達也、増尾友佑、藤田健一、北村正典、中道範隆、佐々木康綱、国嶋崇隆、加藤将夫
- Organizer
  日本薬物動態学会第30回年会
- Place of Presentation
  東京
- Year and Date
  2015-11-12
- Data Source
  KAKENHI-PROJECT-26860099
[Presentation] メタボローム解析による膜輸送体SLC22A4の糖代謝への関与の探索2015
- Author(s)
  大庭悠里、増尾友佑、山田耕平、中道範隆、国嶋崇隆、加藤将夫
- Organizer
  日本薬物動態学会第30回年会
- Place of Presentation
  東京
- Year and Date
  2015-11-12
- Data Source
  KAKENHI-PROJECT-26860099
[Presentation] 膜輸送体OCTN1遺伝子変異体によるビグアニドの輸送特性2015
- Author(s)
  二木梓、増尾友佑、中道範隆、加藤将夫
- Organizer
  日本薬物動態学会第30回年会
- Place of Presentation
  東京
- Year and Date
  2015-11-12
- Data Source
  KAKENHI-PROJECT-26860099
[Presentation] 膜輸送体OCTN1/SLC22A4を利用した炎症疾患予防と治療の可能性2014
- Author(s)
  加藤将夫、増尾友佑、中道範隆
- Organizer
  第9回遺伝子栄養学研究会学術集会
- Place of Presentation
  札幌北広島クラッセホテル（北海道北広島市）
- Year and Date
  2014-09-19
- Invited
- Data Source
  KAKENHI-PROJECT-24390040
[Presentation] GABA受容体作用薬の効果に及ぼす有機カチオントランスポーターOCTN1の関与2014
- Author(s)
  中道範隆、西山美沙、石本尚大、増尾友佑、加藤将夫
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本大学黒髪キャンパス等
- Data Source
  KAKENHI-PROJECT-24390040
[Presentation] 膜輸送体OCTN1の遺伝子変異による輸送活性への影響2014
- Author(s)
  二木梓、増尾友佑、川畑志織、中道範隆、加藤将夫
- Organizer
  第126回日本薬学会北陸支部会
- Place of Presentation
  金沢大学角間キャンパス（石川県金沢市）
- Year and Date
  2014-11-16
- Data Source
  KAKENHI-PROJECT-24390040
[Presentation] 食物由来抗酸化物質エルゴチオネインによるうつ症状軽減作用のメカニズム2014
- Author(s)
  石本尚大、中道範隆、中山敬悟、増尾友佑、加藤将夫
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台国際センター
- Data Source
  KAKENHI-PROJECT-24390040
[Presentation] 膜輸送体octn1遺伝子欠損マウスの海馬におけるシナプス形成異常2014
- Author(s)
  中道範隆、田中悠一、石本尚大、細谷拓史、増尾友佑、加藤将夫
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台国際センター
- Data Source
  KAKENHI-PROJECT-24390040
[Presentation] OCTN1/SLC22A4の生体内基質エルゴチオネインの脳内分布と抗うつ作用2013
- Author(s)
  中山敬悟、中道範隆、石本尚大、杉浦智子、増尾友佑、若山友彦、井関尚一、関口博太、須藤慶太、杉正人、宇住晃治、加藤将夫
- Organizer
  日本薬物動態学会第28回年会
- Place of Presentation
  タワーホール船堀
- Data Source
  KAKENHI-PROJECT-24390040
[Presentation] 膜輸送体octn1の遺伝子欠損が神経発達関連遺伝子に及ぼす影響2013
- Author(s)
  田中悠一、中道範隆、石本尚大、細谷拓史、増尾友佑、加藤将夫
- Organizer
  日本薬学会北陸支部第125回例会
- Place of Presentation
  北陸大学薬学部アネックスファーム
- Data Source
  KAKENHI-PROJECT-24390040
[Presentation] NASHモデルマウスにおけるトランスポーターOCTN1の発現と局在2013
- Author(s)
  増尾友佑、杉浦智子、酒井佳夫、原田龍一、若山友彦、中道範隆、井関尚一、金子周一、加藤将夫
- Organizer
  日本薬物動態学会第28回年会
- Place of Presentation
  タワーホール船堀
- Data Source
  KAKENHI-PROJECT-24390040
[Presentation] 神経幹細胞に発現する膜輸送体 OCTN1 の機能と病態生理学的意義2013
- Author(s)
  中道範隆、石本尚大、中山敬悟、増尾友佑、加藤将夫
- Organizer
  第35回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  東京大学薬学系研究科
- Data Source
  KAKENHI-PROJECT-24390040
[Presentation] キノコ由来抗酸化成分エルゴチオネインの抗うつ作用2013
- Author(s)
  中道範隆、中山敬悟、石本尚大、増尾友佑、関口博太、須藤慶太、杉正人、宇住晃治、加藤将夫
- Organizer
  第43回日本神経精神薬理学会
- Place of Presentation
  沖縄コンベンションセンター
- Data Source
  KAKENHI-PROJECT-24390040
[Presentation] 脳移行性抗酸化物質エルゴチオネインの神経分化促進作用2013
- Author(s)
  石本尚大、中道範隆、中山敬悟、増尾友佑、加藤将夫
- Organizer
  日本薬学会北陸支部第125回例会
- Place of Presentation
  北陸大学薬学部アネックスファーム
- Data Source
  KAKENHI-PROJECT-24390040
[Presentation] 尿毒症物質による肝膜輸送体OATP1B1の阻害様式
- Author(s)
  小木達也、増尾友佑、藤田健一、北村正典、奥村英典、中道範隆、佐々木康綱、国嶋崇隆、加藤将夫
- Organizer
  第36回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  徳島大学大塚講堂、藤井節郎記念ホール
- Year and Date
  2014-11-20 – 2014-11-21
- Data Source
  KAKENHI-PROJECT-26860099
[Presentation] Functional expression of OCTN1/SLC22A4 in intestinal macrophages during gastrointestinal inflammation.
- Author(s)
  Takuya Shimizu, Yusuke Masuo, Noritaka Nakamichi and Yukio Kato.
- Organizer
  19th North American Regional ISSX Meeting and 29th JSSX Annual Meeting
- Place of Presentation
  Hilton San Francisco（米国）
- Year and Date
  2014-10-19 – 2014-10-23
- Data Source
  KAKENHI-PROJECT-24390040
[Presentation] FUNCTIONAL CHARACTERIZATION OF ORGANIC CATION TRANSPORTER OCTN1 WITH SINGLE NUCLEOTIDE POLYMORPHISMS
- Author(s)
  Masuo Y, Kawabata S, Nakamichi N and Kato Y
- Organizer
  19th North American ISSX Meeting
- Place of Presentation
  San Francisco, U.S.A.
- Year and Date
  2014-10-19 – 2014-10-23
- Data Source
  KAKENHI-PROJECT-26860099
[Presentation] タモギタケエキス末含有成分エルゴチオネインは神経新生を促し抗うつ作用を示す
- Author(s)
  中道範隆、中山敬悟、石本尚大、増尾友佑、関口博太、須藤慶太、杉正人、宇住晃治、加藤将夫
- Organizer
  第８回遺伝子栄養学研究会学術集会
- Place of Presentation
  北広島クラッセホテル
- Data Source
  KAKENHI-PROJECT-24390040
[Presentation] Possible interaction between carnitine/organic cation transporter OCTN1 and ERM proteins during liver fibrosis.
- Author(s)
  Yu Karabayashi, Yusuke Masuo, Ryuich Harada, Noritaka Nakamichi and Yukio Kato.
- Organizer
  上皮バリア・輸送に関するシンポジウム
- Place of Presentation
  立命館大学BKCローム記念館（滋賀県草津市）
- Year and Date
  2014-11-01 – 2014-11-02
- Data Source
  KAKENHI-PROJECT-24390040
[Presentation] 膜輸送体OCTN1の生体内基質エルゴチオネインによる神経分化促進の細胞内メカニズム
- Author(s)
  石本尚大、中道範隆、森田明希、増尾友佑、加藤将夫
- Organizer
  第57回日本神経化学会大会
- Place of Presentation
  奈良県文化会館（奈良県奈良市）
- Year and Date
  2014-09-29 – 2014-10-01
- Data Source
  KAKENHI-PROJECT-24390040
[Presentation] Pharmacodynamic roles of solute carrier OCTN1/SLC22A4 for gabaergic drugs in mice.
- Author(s)
  Misa Nishiyama, Noritaka Nakamichi, Yusuke Masuo and Yukio Kato.
- Organizer
  19th North American Regional ISSX Meeting and 29th JSSX Annual Meeting
- Place of Presentation
  Hilton San Francisco（米国）
- Year and Date
  2014-10-19 – 2014-10-23
- Data Source
  KAKENHI-PROJECT-24390040
[Presentation] Functional characterization of organic cation transporter OCTTN1 with single nucleotide polymorphisms.
- Author(s)
  Yusuke Masuo, Shiori Kawabata, Noritaka Nakamichi and Yukio Kato.
- Organizer
  19th North American Regional ISSX Meeting and 29th JSSX Annual Meeting
- Place of Presentation
  Hilton San Francisco（米国）
- Year and Date
  2014-10-19 – 2014-10-23
- Data Source
  KAKENHI-PROJECT-24390040
[Presentation] 膜輸送タンパク質OCTN1/SLC22A4を標的とする精神神経疾患治療
- Author(s)
  中道範隆、増尾友佑、加藤将夫
- Organizer
  第57回日本神経化学会大会
- Place of Presentation
  奈良県文化会館
- Year and Date
  2014-09-29 – 2014-10-01
- Data Source
  KAKENHI-PROJECT-24390040

1. Kato Yukio (30251440)

# of Collaborated Projects: 1 results

# of Collaborated Products: 30 results
2. SAKAI Yoshio (80401925)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. WAKAYAMA Tomohiko (70305100)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. NAKAMICHI Noritaka (10401895)

# of Collaborated Projects: 1 results

# of Collaborated Products: 30 results
5. SUGIURA Tomoko (70542190)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
6. 長野隆男 (20304660)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 矢野博己 (20248272)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 西内巧 (20334790)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 小柳えり (50804647)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 平尾敦 (90343350)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. SASAKI Yasutsuna

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 本多政夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 岡田光

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 藤田健一

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Masuo Yusuke 増尾 友佑

MASUO Yusuke 増尾 友佑

Research Projects

Research Products

Co-Researchers

肝選択的ノックダウンによる肝排出膜輸送体の包括的かつ定量的な機能評価系の構築Principal Investigator

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Lifestyle-related disease prevention effects of nanofiber technology-treated vegetables and clarification of their mechanism

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Elucidation of molecular mechanisms of hematopoietic stem aging

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Analysis of the transport of active metabolites by hepatic efflux transporters and identification of physiological substrates using machine learning-based metabolomicsPrincipal Investigator

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Searching for endogenous substrates of organic cation transporters by selective metabolomicsPrincipal Investigator

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Developments in estimation of the functional changes of transporters and drug metabolizing enzymes during renal failurePrincipal Investigator

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Inhibitory mechanisms of hepatic uptake transporters/OATP during renal failurePrincipal Investigator

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Investigation of pathophysiological roles of transporter for antioxidant with an aim to develop pharmacotherapeutics of inflammatory organ diseases

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[Journal Article] L-type amino acid transporter 1 in hypothalamic neurons in mice maintains energy and bone homeostasis.2023

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[Journal Article] Adeno-associated virus-mediated knockdown demonstrates the major role of hepatic Bcrp in the overall disposition of the active metabolite of the tyrosine kinase inhibitor regorafenib in mice.2023

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[Journal Article] A physiologically based pharmacokinetic and pharmacodynamic model for disposition of FF-10832.2022

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[Journal Article] Discrimination of hand-foot skin reaction caused by tyrosine kinase inhibitors based on direct keratinocyte toxicity and vascular endothelial growth factor receptor-2 inhibition2022

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[Journal Article] Identification of Food-Derived Isoflavone Sulfates as Inhibition Markers for Intestinal Breast Cancer Resistance Proteins.2021

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[Journal Article] Effects of probenecid on hepatic and renal disposition of hexadecanedioate, an endogenous substrate of Organic anion transporting polypeptide 1b in rats.2021

Author(s)

Masuo Yusuke 増尾友佑

MASUO Yusuke 増尾友佑