Uemura Norihito 上村紀仁

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UEMURA Norihito 上村紀仁

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Researcher Number	90749045
Affiliation (Current)	2025: 大阪公立大学, 大学院医学研究科, 講師
Affiliation (based on the past Project Information) *help	2024: 京都大学, 医学研究科, 特定講師 2016 – 2018: 京都大学, 医学研究科, 特定助教 2017: 京都大学, 大学院医学研究科, 特定助教 2017: 京都大学, 大学院医学研究科臨床神経学, 特定助教 2015: 京都大学, 医学(系)研究科(研究院), 助教 2015: 京都大学, 大学院医学研究科, 特定助教
Review Section/Research Field	Principal Investigator Neurology / Basic Section 52020:Neurology-related Except Principal Investigator Neurology
Keywords	Principal Investigator パーキンソン病 / アルファシヌクレイン / マーモセット / 多系統萎縮症 / モデルマウス / マウスモデル / 伝播 / αシヌクレイン / メダカ / 自然免疫 / ゴーシェ病 … More Except Principal Investigator … More パーキンソン病 / 脳神経疾患 / α-シヌクレイン / メダカ / 薬理学 / 神経科学 / スクリーニング / シヌクレイン / 薬剤スクリーニング / ゴーシェ病 / マウス / GBA1 / 脂質 / αシヌクレイン / GBA / α‐シヌクレイン Less

Establishment of research basis for multiple system atrophy based on disease-specific alpha-synuclein filamentsPrincipal Investigator
- Principal Investigator
  
  上村紀仁
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Kyoto University
Development of novel mice models replicating Parkinson's disease pathology from its initial lesionPrincipal Investigator
- Principal Investigator
  
  Uemura Norihito
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurology
- Research Institution
  Kyoto University
Drug screening for suppression of alpha-synulcein expression
- Principal Investigator
  
  Uemura Maiko
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurology
- Research Institution
  Kyoto University
Genetic research on Parkinson's disease using medaka fishPrincipal Investigator
- Principal Investigator
  
  Uemura Norihito
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurology
- Research Institution
  Kyoto University
Unveiling the Pathological Mechanisms and Developing New Treatment of Parkinsons Disease Caused by GBA1 Mutations
- Principal Investigator
  
  Takahashi Ryosuke
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Neurology
- Research Institution
  Kyoto University
Analyzing the pathogenesis of neurodegenerative diseases using medaka with multigene mutations.
- Principal Investigator
  
  Takahashi Ryosuke
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurology
- Research Institution
  Kyoto University

All 2018 2017 2016 2015 2014

All Journal Article Presentation Book

[Book] エキスパートに学ぶパーキンソン病・パーキンソニズムQ&A2017
- Author(s)
  髙橋良輔、上村紀仁他
- Total Pages
  248
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-15K19486
[Journal Article] パーキンソン病（２）αシヌクレイン2018
- Author(s)
  上村紀仁
- Journal Title
  
  和光純薬時報
  
  Volume: 86 Pages: 12-14
- Data Source
  KAKENHI-PROJECT-17K16119
[Journal Article] Inoculation of α-synuclein preformed fibrils into the mouse gastrointestinal tract induces Lewy body-like aggregates in the brainstem via the vagus nerve2018
- Author(s)
  Uemura Norihito、Yagi Hisashi、Uemura Maiko T.、Hatanaka Yusuke、Yamakado Hodaka、Takahashi Ryosuke
- Journal Title
  
  Molecular Neurodegeneration
  
  Volume: 13 Issue: 1 Pages: 21-21
- DOI
  10.1186/s13024-018-0257-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-17H05698, KAKENHI-PROJECT-17K16119, KAKENHI-PROJECT-16K09672
[Journal Article] Zonisamide inhibits monoamine oxidase and enhances motor performance and social activity2017
- Author(s)
  Uemura Maiko T.、Asano Takeshi、Hikawa Rie、Yamakado Hodaka、Takahashi Ryosuke
- Journal Title
  
  Neuroscience Research
  
  Volume: 124 Pages: 25-32
- DOI
  10.1016/j.neures.2017.05.008
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05698, KAKENHI-PROJECT-15H02540, KAKENHI-PROJECT-16K19509, KAKENHI-PROJECT-16K09672
[Journal Article] GBA遺伝子変異とパーキンソン病2017
- Author(s)
  中西悦郎、上村紀仁
- Journal Title
  
  医学のあゆみ
  
  Volume: 262 Pages: 597-601
- Data Source
  KAKENHI-PROJECT-15H02540
[Journal Article] Pericyte-derived bone morphogenetic protein 4 underlies white matter damage after chronic hypoperfusion2017
- Author(s)
  Uemura Maiko T.、Ihara Masafumi、Maki Takakuni、Nakagomi Takayuki、Kaji Seiji、Uemura Kengo、Matsuyama Tomohiro、Kalaria Raj N.、Kinoshita Ayae、Takahashi Ryosuke
- Journal Title
  
  Brain Pathology
  
  Volume: 31 May Issue: 4 Pages: 1-15
- DOI
  10.1111/bpa.12523
- NAID
  120006305874
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05698, KAKENHI-PROJECT-15K09329, KAKENHI-PROJECT-16K19509
[Journal Article] αシヌクレインの凝集・伝播と細胞死2017
- Author(s)
  澤村正典、上村紀仁、高橋良輔
- Journal Title
  
  医学のあゆみ
  
  Volume: 262 Pages: 585-589
- Data Source
  KAKENHI-PROJECT-17K16119
[Journal Article] GBA遺伝子変異とパーキンソン病2017
- Author(s)
  中西悦郎、上村紀仁
- Journal Title
  
  医学のあゆみ
  
  Volume: 262 Pages: 597-601
- Data Source
  KAKENHI-PROJECT-17K16119
[Journal Article] αシヌクレインの凝集・伝播と細胞死2017
- Author(s)
  澤村正典、上村紀仁、高橋良輔
- Journal Title
  
  医学のあゆみ
  
  Volume: 262 Pages: 585-589
- Data Source
  KAKENHI-PROJECT-15H02540
[Journal Article] メダカを用いたパーキンソン病研究2016
- Author(s)
  上村紀仁
- Journal Title
  
  実験医学（増刊）
  
  Volume: 34 Pages: 187-194
- Data Source
  KAKENHI-PROJECT-15K19486
[Journal Article] Innate immunity regulates α-synuclein clearance2016
- Author(s)
  Sawamura M, Uemura N, Takahashi R
- Journal Title
  
  Movement Disorders
  
  Volume: 0 Issue: 5 Pages: 0-0
- DOI
  10.1002/mds.26571
- Open Access
- Data Source
  KAKENHI-PROJECT-15H02540, KAKENHI-PROJECT-26670442
[Journal Article] メダカを用いたパーキンソン病研究2016
- Author(s)
  上村紀仁
- Journal Title
  
  実験医学（増刊）
  
  Volume: 34 Pages: 187-94
- Data Source
  KAKENHI-PROJECT-15H02540
[Journal Article] Viable neuronopathic Gaucher disease model in medaka (Oryzias latipes) displays axonal accumulation of alpha-synuclein2015
- Author(s)
  Norihito Uemura, Masato Koike, Satoshi Ansai, Masato Kinoshita, Tomoko Ishikawa-Fujiwara, Hideaki Matsui, Kiyoshi Naruse, Naoaki Sakamoto, Yasuo Uchiyama, Takeshi Todo, Shunichi Takeda, Hodaka Yamakado, Ryosuke Takahashi
- Journal Title
  
  PLoS Genetics
  
  Volume: 11 Issue: 4 Pages: 1-14
- DOI
  10.1371/journal.pgen.1005065
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13J01682, KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-23221005, KAKENHI-PROJECT-23241023, KAKENHI-PROJECT-25460276, KAKENHI-PUBLICLY-26111519, KAKENHI-PROJECT-26670442, KAKENHI-PROJECT-26860666, KAKENHI-PROJECT-15K19486, KAKENHI-PLANNED-23111002, KAKENHI-ORGANIZER-23111001, KAKENHI-PLANNED-23111004, KAKENHI-PROJECT-15H02540, KAKENHI-PROJECT-25281019, KAKENHI-PROJECT-15H05713
[Journal Article] パーキンソン病の動物モデル2015
- Author(s)
  上村紀仁
- Journal Title
  
  Pharma medica
  
  Volume: 33 Pages: 25-29
- Data Source
  KAKENHI-PROJECT-15K19486
[Journal Article] メダカのパーキンソン病モデル2015
- Author(s)
  上村紀仁
- Journal Title
  
  細胞工学
  
  Volume: 34 Pages: 1166-77
- NAID
  40020669016
- Data Source
  KAKENHI-PROJECT-15K19486
[Journal Article] The Parkinson's Disease-Associated Protein Kinase LRRK2 Modulates Notch Signaling through the Endosomal Pathway.2015
- Author(s)
  Imai Y, Kobayashi Y, Inoshita T, Meng H, Arano T, Uemura K, Asano T, Yoshimi K, Zhang CL, Matsumoto G, Ohtsuka T, Kageyama R, Kiyonari H, Shioi G, Nukina N, Hattori N, Takahashi R
- Journal Title
  
  PLoS Genet.
  
  Volume: 11 Issue: 9 Pages: e1005503-e1005503
- DOI
  10.1371/journal.pgen.1005503
- NAID
  120005946994
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06773, KAKENHI-PROJECT-26860219, KAKENHI-PLANNED-23111002, KAKENHI-PUBLICLY-15H01561, KAKENHI-PLANNED-23111003, KAKENHI-PROJECT-15H02540, KAKENHI-PROJECT-15H04842, KAKENHI-PROJECT-26670442
[Journal Article] Design, evaluation, and screening methods for efficient targeted mutage nesis with TALENs' in medaka.2014
- Author(s)
  S. Ansai, K. Inohaya, Y. Yoshiu ra, M. Schartl, N. Uemura, R. Takahashi, M. Kinoshita
- Journal Title
  
  Development, Growth & Differentiation
  
  Volume: 56 Issue: 1 Pages: 98-107
- DOI
  10.1111/dgd.12104
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13J01682, KAKENHI-ORGANIZER-23111001, KAKENHI-PROJECT-23390232, KAKENHI-PROJECT-26670442
[Presentation] Pathological pathway via the olfactory bulb represents non-motor symptoms of Parkinson’s disease2018
- Author(s)
  Norihito Uemura, Hodaka Yamakado, Ryosuke Takahashi
- Organizer
  第59回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-17K16119
[Presentation] Gut-to-brain propagation of α-synuclein aggregates in mice2018
- Author(s)
  Norihito Uemura, Shinya Okuda, Hisashi Yagi, Ryosuke Takahashi
- Organizer
  第12回MDSJ
- Data Source
  KAKENHI-PROJECT-17K16119
[Presentation] A novel mice model for Parkinson's disease: fibril-inoculated mutant α-synuclein BAC transgenic mice2017
- Author(s)
  奥田真也、上村紀仁、上村麻衣子、山門穂高、高橋良輔
- Organizer
  World congress of Neurology
- Data Source
  KAKENHI-PROJECT-16K19509
[Presentation] 遺伝子改変とαシヌクレイン接種による新規パーキンソン病モデルマウスの開発2017
- Author(s)
  上村紀仁
- Organizer
  ConBio2017
- Data Source
  KAKENHI-PROJECT-17K16119
[Presentation] Pathological role of GBA2 in GBA1-deficient neuronopathic Gaucher’s disease model of medaka2017
- Author(s)
  中西悦郎、上村紀仁、秋山央子、木下政人、山門穂高、武田俊一、平林義雄、高橋良輔
- Organizer
  第40回神経科学学会
- Data Source
  KAKENHI-PROJECT-15H02540
[Presentation] Pathological role of GBA2 in GBA1-deficient neuronopathic Gaucher’s disease model of medaka2017
- Author(s)
  Etsuro Nakanishi, Norihito Uemura, Satoko Akiyama, Masato Kinoshita, Hodaka Yamakado, Shun-ichi Takeda, Yoshio Hirabayashi, Ryosuke Takahashi
- Organizer
  WCN2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02540
[Presentation] Is the GBA2 a new modifier for Gauchers’s disease and GBA1-related Parkinson’s disease?2017
- Author(s)
  Etsuro Nakanishi, Norihito Uemura, Satoko Akiyama, Masato Kinoshita, Hodaka Yamakado, Shun-ichi Takeda, Yoshio Hirabayashi, Ryosuke Takahashi
- Organizer
  MDS2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02540
[Presentation] 遺伝子改変とαシヌクレイン接種による新規パーキンソン病モデルマウスの開発2017
- Author(s)
  上村紀仁
- Organizer
  ConBio2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02540
[Presentation] Inoculation of alpha-synuclein fibrils into the mouse gastrointestinal tract induces Lewy-like pathology in the brain via the vagal nerve2017
- Author(s)
  上村紀仁、上村麻衣子、八木寿梓、髙橋良輔
- Organizer
  WCN2017
- Data Source
  KAKENHI-PROJECT-17K16119
[Presentation] αシヌクレインの消化管から脳幹への伝播について2017
- Author(s)
  上村紀仁、髙橋良輔
- Organizer
  第70回日本自律神経学会総会（JSNR 2017）
- Data Source
  KAKENHI-PROJECT-17K16119
[Presentation] Inoculation of alpha-synuclein fibrils into the mouse gastrointestinal tract induces Lewy-like pathology in the brain via the vagal nerve2017
- Author(s)
  上村紀仁、上村麻衣子、八木寿梓、高橋良輔
- Organizer
  World congress of Neurology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19509
[Presentation] Inoculation of alpha-synuclein fibrils into the mouse gastrointestinal tract induces Lewy-like pathology in the brain via the vagal nerve2017
- Author(s)
  上村紀仁、八木寿梓、髙橋良輔
- Organizer
  第40回神経科学学会
- Data Source
  KAKENHI-PROJECT-17K16119
[Presentation] αシヌクレイントランスジェニックマウスへのフィブリル脳内接種によるパーキンソン病モデル作製2017
- Author(s)
  奥田真也、上村紀仁、上村麻衣子、山門穂高、高橋良輔
- Organizer
  第11回パーキンソン病・運動障害疾患コングレス
- Data Source
  KAKENHI-PROJECT-16K19509
[Presentation] Does endogenic alpha-synuclein have protective property in human alpha-synuclein transgenic models?2016
- Author(s)
  Masanori Sawamura, Norihito Uemura, Ryosuke Takahashi
- Organizer
  5th Asian and Oceanian Parkinson's Disease and Movement Disorders Congress
- Place of Presentation
  Manila
- Year and Date
  2016-03-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670442
[Presentation] Pathological studies in Parkinson's disease2016
- Author(s)
  Seiji Kaji, Norihito Uemura, Takakuni Maki, Makoto Urushitani, Ryosuke Takahash
- Organizer
  Symposium for Young Neurologists and Emerging Researchers Grooming for Interaction and Excellence in Science (SYNERGIES)
- Place of Presentation
  マニラ
- Year and Date
  2016-03-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02540
[Presentation] Pathological role of GBA2 in GBA1-deficient neuronopathic Gaucher’s disease model of medaka2016
- Author(s)
  E Nakanishi, N Uemura, H Akiyama, M Kinoshita, H Yamakado, T Shunichi, Y Hirabayashi, R Takahashi
- Organizer
  第39回神経科学大会
- Place of Presentation
  横浜
- Year and Date
  2016-07-20
- Data Source
  KAKENHI-PROJECT-15H02540
[Presentation] Pathological studies in Parkinson's disease2016
- Author(s)
  Seiji Kaji, Norihito Uemura, Takakuni Maki, Makoto Urushitani, Ryosuke Takahashi
- Organizer
  Symposium for Young Neurologists and Emerging Researchers Grooming for Interaction and Excellence in Science (SYNERGIES)
- Place of Presentation
  Manila
- Year and Date
  2016-03-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670442
[Presentation] Glucocerebrosidase deficiency accelerates the propagation of alpha-Synuclein pathology2016
- Author(s)
  上村紀仁、長谷川成人、髙橋良輔
- Organizer
  第57回日本神経学会学術大会
- Place of Presentation
  神戸
- Year and Date
  2016-05-18
- Data Source
  KAKENHI-PROJECT-16K19509
[Presentation] Inoculation of α-synuclein fibrils to α-synuclein BAC transgenic mice did not accelerate Lewy-like pathology2016
- Author(s)
  奥田真也、上村紀仁、高橋良輔
- Organizer
  第39回神経科学大会
- Place of Presentation
  横浜
- Year and Date
  2016-07-20
- Data Source
  KAKENHI-PROJECT-16K19509
[Presentation] 神経型ゴーシェ病モデルメダカは軸索にアルファシヌクレイン蓄積を示す2016
- Author(s)
  上村紀仁
- Organizer
  日本放射線影響学会－第59回大会－
- Place of Presentation
  広島
- Year and Date
  2016-10-26
- Data Source
  KAKENHI-PROJECT-15H02540
[Presentation] Does inoculation of α-synuclein fibrils promote Lewy-pathology of α-synuclein BAC transgenic mice?2016
- Author(s)
  奥田真也、上村紀仁、生野真嗣、山門穂高、高橋良輔
- Organizer
  第10回パーキンソン病・運動障害疾患コングレス
- Place of Presentation
  京都
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16K19509
[Presentation] Viable neuronopathic Gaucher disease model in medaka (Oryzias latipes) displays axonal accumulation of alpha-synuclein2016
- Author(s)
  Norihito Uemura, Ryosuke Takahashi
- Organizer
  International Meeting on Aquatic Model Organisms for Human Disease and Toxicology Research
- Place of Presentation
  名古屋
- Year and Date
  2016-03-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19486
[Presentation] 神経型ゴーシェ病モデルメダカは軸索にアルファシヌクレイン蓄積を示す2016
- Author(s)
  上村紀仁
- Organizer
  日本放射線影響学会－第59回大会－
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-15K19486
[Presentation] Viable neuronopathic Gaucher disease model in medaka (Oryzias latipes) displays axonal accumulation of alpha-synuclein2016
- Author(s)
  Norihito Uemura, Ryosuke Takahashi
- Organizer
  International Meeting on Aquatic Model Organisms for Human Disease and Toxicology Research
- Place of Presentation
  名古屋
- Year and Date
  2016-03-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02540
[Presentation] Pathological role of GBA2 in GBA1-deficient neuronopathic Gaucher’s disease model of medaka2016
- Author(s)
  E Nakanishi, N Uemura, H Akiyama, M Kinoshita, H Yamakado, T Shunichi, Y Hirabayashi, R Takahashi
- Organizer
  第57回日本神経学会学術大会
- Place of Presentation
  神戸
- Year and Date
  2016-05-21
- Data Source
  KAKENHI-PROJECT-15H02540
[Presentation] 神経型ゴーシェ病モデルメダカの中枢神経におけるGBA2の役割2016
- Author(s)
  中西悦郎、上村紀仁、秋山央子、木下政人、山門穂高、武田俊一、平林義雄、高橋良輔
- Organizer
  第10回パーキンソン病・運動障害疾患コングレス
- Place of Presentation
  京都
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-15H02540
[Presentation] Viable neuronopathic Gaucher disease model in medaka (Oryzias latipes) displays axonal accumulation of alpha-synuclein2016
- Author(s)
  Norihito Uemura, Ryosuke Takahashi
- Organizer
  International Meeting on Aquatic Model Organisms for Human Disease and Toxicology Research
- Place of Presentation
  Nagoya
- Year and Date
  2016-03-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670442
[Presentation] Does endogenic alpha-synuclein have protective property in human alpha-synuclein transgenic models?2016
- Author(s)
  Masanori Sawamura, Norihito Uemura, Ryosuke Takahashi
- Organizer
  5th Asian and Oceanian Parkinson's Disease and Movement Disorders Congress
- Place of Presentation
  マニラ
- Year and Date
  2016-03-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02540
[Presentation] Therapeutic targets and strategies for Alzheimer’s and Parkinson’s diseases2015
- Author(s)
  上村紀仁
- Organizer
  第58回日本神経化学会大会
- Place of Presentation
  さいたま
- Year and Date
  2015-09-12
- Data Source
  KAKENHI-PROJECT-15H02540
[Presentation] Medaka fish model of Parkinson’s disease2015
- Author(s)
  Norihito Uemura, Ryosuke Takahashi
- Organizer
  GEO-PD
- Place of Presentation
  Tokyo
- Year and Date
  2015-10-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670442
[Presentation] Medaka fish model of Parkinson’s disease2015
- Author(s)
  Norihito Uemura, Ryosuke Takahashi
- Organizer
  10th GEO-PD
- Place of Presentation
  東京
- Year and Date
  2015-10-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02540
[Presentation] Gaucher disease model in medaka displays axonal accumulation of alpha-synuclein2015
- Author(s)
  Norihito Uemura
- Organizer
  第56回日本神経学会学術大会
- Place of Presentation
  新潟
- Year and Date
  2015-05-20
- Data Source
  KAKENHI-PROJECT-15K19486
[Presentation] Gaucher disease model in medaka displays axonal accumulation of alpha-synuclein2015
- Author(s)
  上村紀仁
- Organizer
  第56回日本神経学会学術大会
- Place of Presentation
  新潟
- Year and Date
  2015-05-20
- Data Source
  KAKENHI-PROJECT-15H02540
[Presentation] Gaucher disease model in medaka displays axonal accumulation of alpha-synuclein2015
- Author(s)
  Norihito Uemura
- Organizer
  第58回日本神経化学会大会
- Place of Presentation
  さいたま
- Year and Date
  2015-09-12
- Data Source
  KAKENHI-PROJECT-26670442
[Presentation] Analysis of the ATP13A2mutant (PARK9) medaka (Oryziaslatipes)2015
- Author(s)
  Yosuke Taruno, Hideaki Matsui, Norihito Uemura, Hodaka Yamakado, Ryoruke Takahashi
- Organizer
  第56回日本神経学会学術大会
- Place of Presentation
  新潟
- Year and Date
  2015-05-22
- Data Source
  KAKENHI-PROJECT-26670442
[Presentation] Gaucher disease model in medaka displays axonal accumulation of alpha-synuclein2015
- Author(s)
  Norihito Uemura
- Organizer
  第56回日本神経学会学術大会
- Place of Presentation
  新潟
- Year and Date
  2015-05-20
- Data Source
  KAKENHI-PROJECT-26670442
[Presentation] Gaucher disease model in medaka displays axonal accumulation of alpha-synuclein2015
- Author(s)
  Norihito Uemura
- Organizer
  第58回日本神経化学会大会
- Place of Presentation
  さいたま
- Year and Date
  2015-09-12
- Data Source
  KAKENHI-PROJECT-15K19486
[Presentation] 神経型ゴーシェ病メダカは軸索にアルファシヌクレイン蓄積を示す2015
- Author(s)
  上村紀仁
- Organizer
  BMB2015
- Place of Presentation
  神戸
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PROJECT-15K19486
[Presentation] Pathological role of GBA2 in GBA1-deficient neuronopathic Gaucher’s disease model of medaka2015
- Author(s)
  中西　悦郎、上村紀仁、秋山央子、木下政人、山門穂高、武田俊一、平林義雄、高橋良輔
- Organizer
  第38回日本神経科学大会
- Place of Presentation
  神戸
- Year and Date
  2015-07-30
- Data Source
  KAKENHI-PROJECT-26670442
[Presentation] Pathological role of the innate immune system in neuronopathic Gaucher disease model in medaka2015
- Author(s)
  Norihito Uemura, Etsuro Nakanishi, Masato Kinoshita, Hodaka Yamakado, Shunichi Takeda, Ryoruke Takahashi
- Organizer
  第38回日本神経科学大会
- Place of Presentation
  神戸
- Year and Date
  2015-07-30
- Data Source
  KAKENHI-PROJECT-26670442
[Presentation] Medaka fish model of Parkinson’s disease2015
- Author(s)
  Norihito Uemura, Ryosuke Takahashi
- Organizer
  10th GEO-PD
- Place of Presentation
  東京
- Year and Date
  2015-10-02
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19486
[Presentation] Parkinson’s disease Pathogenesis α-synuclein2015
- Author(s)
  樽野陽亮、松井秀彰、上村紀仁、山門穂高、髙橋良輔
- Organizer
  第56回日本神経学会学術大会
- Place of Presentation
  新潟
- Year and Date
  2015-05-20
- Data Source
  KAKENHI-PROJECT-15H02540
[Presentation] Pathological role of the innate immune system in neuronopathic Gaucher disease model in medaka2015
- Author(s)
  上村紀仁、中西悦郎、木下政人、山門穂高、武田俊一、高橋良輔
- Organizer
  第38回日本神経科学大会
- Place of Presentation
  神戸
- Year and Date
  2015-07-30
- Data Source
  KAKENHI-PROJECT-15H02540
[Presentation] Pathological role of GBA2 in GBA1-deficient neuronopathic Gaucher’s disease model of medaka2015
- Author(s)
  中西悦郎、上村紀仁、秋山央子、木下政人、山門穂高、武田俊一、平林義雄、高橋良輔
- Organizer
  第38回日本神経科学大会
- Place of Presentation
  神戸
- Year and Date
  2015-07-30
- Data Source
  KAKENHI-PROJECT-15H02540
[Presentation] GBA変異メダカは軸索内にalpha-synucleinを蓄積する2014
- Author(s)
  上村紀仁、石川智子、木下政人、小池正人、松井秀彰、山門穂高、内山安男、藤堂剛、武田俊一、髙橋良輔
- Organizer
  第23回日本Cell Death学会学術集会
- Place of Presentation
  東京
- Year and Date
  2014-07-18
- Data Source
  KAKENHI-PROJECT-26670442
[Presentation] GBA変異メダカは脳にalpha-synuclein凝集体を形成する2014
- Author(s)
  上村紀仁、石川智子、木下政人、小池正人、松井秀彰、山門穂高、植村健吾、内山安男、藤堂剛、武田俊一、髙橋良輔
- Organizer
  第５５回日本神経学会
- Place of Presentation
  福岡
- Year and Date
  2014-05-24
- Data Source
  KAKENHI-PROJECT-26670442
[Presentation] Neuronopathic Gaucher’s disease model of medaka displayed axonal accumulation of alpha-synuclein2014
- Author(s)
  Norihito Uemura, Masato Koike, Masato Kinoshita, Tomoko Fujiwara-Ishikawa4, Hideaki Matsui5, Hodaka Yamakado,Yasuo Uchiyama, Takeshi Todo, Shun-ichi Takeda, Ryosuke Takahashi
- Organizer
  4th Asian and Oceanian Parkinson’s Disease and Movement Disorders Congress
- Place of Presentation
  Pattaya (Thailand)
- Year and Date
  2014-11-30
- Data Source
  KAKENHI-PROJECT-26670442
[Presentation] Alpha-synuclein accumulation in Gaucher disease model of medaka does not contribute to neurodegeneration2014
- Author(s)
  Norihito Uemura, Tomoko Fujiwara-Ishikawa, Masato Kinoshita, Masato Koike, Hideaki Matsui, Hodaka Yamakado,Yasuo Uchiyama, Takeshi Todo, Shun-ichi Takeda and Ryosuke Takahashi
- Organizer
  第37回日本神経科学大会
- Place of Presentation
  横浜
- Year and Date
  2014-09-12
- Data Source
  KAKENHI-PROJECT-26670442

1. Takahashi Ryosuke (90216771)

# of Collaborated Projects: 3 results

# of Collaborated Products: 31 results
2. 木下政人 (60263125)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
3. NAKANISHI Etsuro

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
4. YAMAKADO Hodaka (10378771)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. Uemura Maiko (00767395)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
6. 秋山央子 (80623462)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
7. 尾上浩隆 (80214196)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. Ikuno Masashi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. OKUDA Shinya

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
10. TAGUCHI Tomoyuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. TAMANO Ryotaro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 山門穗高

# of Collaborated Projects: 0 results

# of Collaborated Products: 9 results
13. 大塚俊之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Uemura Norihito 上村 紀仁

UEMURA Norihito 上村 紀仁

Research Projects

Research Products

Co-Researchers

Establishment of research basis for multiple system atrophy based on disease-specific alpha-synuclein filamentsPrincipal Investigator

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Development of novel mice models replicating Parkinson's disease pathology from its initial lesionPrincipal Investigator

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Drug screening for suppression of alpha-synulcein expression

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Genetic research on Parkinson's disease using medaka fishPrincipal Investigator

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Unveiling the Pathological Mechanisms and Developing New Treatment of Parkinsons Disease Caused by GBA1 Mutations

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Analyzing the pathogenesis of neurodegenerative diseases using medaka with multigene mutations.

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[Book] エキスパートに学ぶパーキンソン病・パーキンソニズムQ&A2017

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[Journal Article] パーキンソン病（２）αシヌクレイン2018

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[Journal Article] Inoculation of α-synuclein preformed fibrils into the mouse gastrointestinal tract induces Lewy body-like aggregates in the brainstem via the vagus nerve2018

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[Journal Article] Zonisamide inhibits monoamine oxidase and enhances motor performance and social activity2017

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[Journal Article] GBA遺伝子変異とパーキンソン病2017

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[Journal Article] Pericyte-derived bone morphogenetic protein 4 underlies white matter damage after chronic hypoperfusion2017

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NAID

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[Journal Article] αシヌクレインの凝集・伝播と細胞死2017

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[Journal Article] GBA遺伝子変異とパーキンソン病2017

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[Journal Article] αシヌクレインの凝集・伝播と細胞死2017

Author(s)

Uemura Norihito 上村紀仁

UEMURA Norihito 上村紀仁