Tanihara Fuminori 谷原史倫

Researcher Number	90754680
Other IDs
Affiliation (Current)	2025: 徳島大学, バイオイノベーション研究所, 教授 2025: 自治医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2020 – 2024: 自治医科大学, 医学部, 准教授 2017 – 2021: 徳島大学, 大学院社会産業理工学研究部(生物資源産業学域), 特任助教 2020: 自治医科大学, 先端医療技術開発センター, 准教授
Review Section/Research Field	Principal Investigator Basic Section 42040:Laboratory animal science-related / Medium-sized Section 42:Veterinary medical science, animal science, and related fields / Basic Section 42030:Animal life science-related Except Principal Investigator Medium-sized Section 90:Biomedical engineering and related fields / Basic Section 55040:Respiratory surgery-related / Basic Section 90110:Biomedical engineering-related / Integrative animal science / Veterinary medical science, Animal science, and related fields
Keywords	Principal Investigator CRISPR/Cas9 / ゲノム編集 / ブタ / 腎不全 / CPP / Klotho / アフリカ豚熱 / モデルブタ / 糖尿病性腎症 / 体外受精 / エレクトロポレーション … More Except Principal Investigator … More ブタ / ゲノム編集 / 異種移植 / キメラ / SALL1 / TP53 / モデル動物 / 肺オルガノイド / p53遺伝子改変ブタ / 肺の修復・再生 / 急性肺障害 / マイクロミニブタ / ミニブタ / 免疫不全 / 染色体工学 / HLA A24 / GalT / 人工染色体 / 受精卵 / 代替臓器 / CRISPR/Cas９ / 内在性レトロウイルス Less

Development of animal model for kidney-specific spontaneous tumours
- Principal Investigator
  
  音井威重
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  The University of Tokushima
慢性腎臓病に起因する健康寿命減衰をリン（CPP）の除去により防ぎ止める橋渡し研究Principal Investigator
- Principal Investigator
  
  谷原史倫
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42040:Laboratory animal science-related
- Research Institution
  Jichi Medical University
Generation of African Swine Fever virus-resistant pigs by applying the concept of gene editing technologyPrincipal Investigator
- Principal Investigator
  
  谷原史倫
- Project Period (FY)
  2021 – 2025
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 42:Veterinary medical science, animal science, and related fields
- Research Institution
  Jichi Medical University
Generation of a pig model for the diabetic nephropathy using gene editing technologyPrincipal Investigator
- Principal Investigator
  
  Tanihara Fuminori
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 42030:Animal life science-related
- Research Institution
  Jichi Medical University
  The University of Tokushima
Production of immunodeficient micro-mini pig using genome editing technology.
- Principal Investigator
  
  HIRATA Maki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  The University of Tokushima
The role of p53 during airway and lung injury, repair and regeneration using TP53-mutant porcine
- Principal Investigator
  
  TOBA Hiroaki
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  The University of Tokushima
Production of pigs for safe xenotransplantation by controlling infectious porcine endogenous retrovirus (PERV)
- Principal Investigator
  
  OTOI Takeshige
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Veterinary medical science, Animal science, and related fields
- Research Institution
  The University of Tokushima
Production of genetically modified pigs by combined techniques of chromosome engineering and genome editing
- Principal Investigator
  
  OTOI Takeshige
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Integrative animal science
- Research Institution
  The University of Tokushima

All 2023 2022 2021 2020 2019 2018 2017

All Journal Article Presentation Patent

[Journal Article] GHR-mutant pig derived from domestic pig and microminipig hybrid zygotes using CRISPR/Cas9 system2023
- Author(s)
  Tanihara Fuminori、Hirata Maki、Namula Zhao、Wittayarat Manita、Do Lanh Thi Kim、Lin Qingyi、Takebayashi Koki、Hara Hiromasa、Nagahara Megumi、Otoi Takeshige
- Journal Title
  
  Molecular Biology Reports
  
  Volume: 50 Issue: 6 Pages: 5049-5057
- DOI
  10.1007/s11033-023-08388-3
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19896
[Journal Article] Pigs with an INS point mutation derived from zygotes electroporated with CRISPR/Cas9 and ssODN2023
- Author(s)
  Tanihara Fuminori、Hirata Maki、Namula Zhao、Do Lanh Thi Kim、Yoshimura Naoaki、Lin Qingyi、Takebayashi Koki、Sakuma Tetsushi、Yamamoto Takashi、Otoi Takeshige
- Journal Title
  
  Frontiers in Cell and Developmental Biology
  
  Volume: 11 Pages: 884340-884340
- DOI
  10.3389/fcell.2023.884340
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06137, KAKENHI-PROJECT-22K19896
[Journal Article] Mosaic TP53 Mutation on Tumour Development in Pigs: A Case Study2023
- Author(s)
  Thongkittidilok Chommanart、Hirata Maki、Lin Qingyi、Torigoe Nanaka、Liu Bin、Sato Yoko、Nagahara Megumi、Tanihara Fuminori、Otoi Takeshige
- Journal Title
  
  Veterinary Medicine International
  
  Volume: 2023 Issue: 1 Pages: 1-6
- DOI
  10.1155/2023/7000858
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19896
[Journal Article] Viability and developmental potential of porcine blastocysts preserved for short term in a chemically defined medium at ambient temperature2022
- Author(s)
  Lin Qingyi、Le Quynh Anh、Takebayashi Koki、Hirata Maki、Tanihara Fuminori、Thongkittidilok Chommanart、Sawamoto Osamu、Kikuchi Takeshi、Otoi Takeshige
- Journal Title
  
  Reproduction in Domestic Animals
  
  Volume: 57 Issue: 5 Pages: 556-563
- DOI
  10.1111/rda.14095
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K19896
[Journal Article] One-Step Generation of Multiple Gene-Edited Pigs by Electroporation of the CRISPR/Cas9 System into Zygotes to Reduce Xenoantigen Biosynthesis2021
- Author(s)
  Tanihara F., Hirata M., Nguyen TN., Sawamoto O., Kikuchi T., Otoi T.
- Journal Title
  
  International journal of molecular sciences
  
  Volume: 22 Issue: 5 Pages: 2249-2249
- DOI
  10.3390/ijms22052249
- NAID
  120007164926
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K12062, KAKENHI-PROJECT-19K16014
[Journal Article] Introduction of a point mutation in the KRAS gene of in vitro fertilized porcine zygotes via electroporation of the CRISPR/Cas9 system with single-stranded oligodeoxynucleotides.2021
- Author(s)
  Wittayarat M., Hirata M., Namula Z., Sato Y., Nguyen TN., Le AQ., Lin Q., Takebayashi K., Tanihara F., Otoi T.
- Journal Title
  
  Animal Science Journal,
  
  Volume: 92 Issue: 1
- DOI
  10.1111/asj.13534
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K12062, KAKENHI-PROJECT-19K16014
[Journal Article] Lipofection-Mediated Introduction of CRISPR/Cas9 System into Porcine Oocytes and Embryos2021
- Author(s)
  Hirata M., Wittayarat M., Namula Z., Le AQ., Lin Q., Takebayashi K., Thongkittidilok C., Tanihara F., Otoi T.
- Journal Title
  
  Animals
  
  Volume: 11 Issue: 2 Pages: 578-578
- DOI
  10.3390/ani11020578
- NAID
  120007147677
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K12062, KAKENHI-PROJECT-19K16014
[Journal Article] Comparison of the effects of introducing the CRISPR/Cas9 system by microinjection and electroporation into porcine embryos at different stages2021
- Author(s)
  Le AQ., Tanihara F., Wittayarat M., Namula Z., Sato Y., Lin Q., Takebayashi K., Hirata M., Otoi T.
- Journal Title
  
  BMC Research Notes
  
  Volume: 14 Issue: 1 Pages: 7-7
- DOI
  10.1186/s13104-020-05412-8
- NAID
  120007147670
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K12062, KAKENHI-PROJECT-19K16014
[Journal Article] Evaluation of multiple gene targeting in porcine embryos by the CRISPR/Cas9 system using electroporation2020
- Author(s)
  Hirata M., Wittayarat M., Namula Z., Le AQ., Lin Q., Nguyen TN., Takebayashi K., Sato Y., Tanihara F., Otoi T.
- Journal Title
  
  Molecular Biology Reports
  
  Volume: 47 Issue: 7 Pages: 5073-5079
- DOI
  10.1007/s11033-020-05576-3
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K12062, KAKENHI-PROJECT-19K16014
[Journal Article] Efficient generation of GGTA1-deficient pigs by electroporation of the CRISPR/Cas9 system into in vitro-fertilized zygotes2020
- Author(s)
  Tanihara F., Hirata M., Nguyen TN., Sawamoto O., Kikuchi T., Masako Doi., Otoi T.
- Journal Title
  
  BMC biotechnology
  
  Volume: 20 Issue: 1 Pages: 40-40
- DOI
  10.1186/s12896-020-00638-7
- NAID
  120007045051
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K12062, KAKENHI-PROJECT-19K16014
[Journal Article] One-step genome editing of porcine zygotes through the electroporation of a CRISPR/Cas9 system with two guide RNAs2020
- Author(s)
  Hirata M., Wittayarat M., Tanihara F., Sato Y., Namula Z., Le AQ., Lin Q., Takebayashi K., Otoi T.
- Journal Title
  
  In Vitro Cellular & Developmental Biology - Animal
  
  Volume: 56 Issue: 8 Pages: 614-621
- DOI
  10.1007/s11626-020-00507-9
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K12062, KAKENHI-PROJECT-19K16014
[Journal Article] Generation of CD163-edited pig via electroporation of the CRISPR/Cas9 system into porcine in vitro-fertilized zygotes2020
- Author(s)
  Tanihara, F., Hirata, M., Nguyen, TN., Le, AQ., Wittayarat, M., Fahrudin, M., Hirano, T., Otoi, T.
- Journal Title
  
  Animal Biotechnology
  
  Volume: - Issue: 2 Pages: 147-154
- DOI
  10.1080/10495398.2019.1668801
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K12062, KAKENHI-PROJECT-19K16014, KAKENHI-PROJECT-17H03938
[Journal Article] Generation of viable PDX1 gene‐edited founder pigs as providers of nonmosaics2020
- Author(s)
  Tanihara F, Hirata M, Thi Nguyen N, Anh Le Q, Hirano T, Otoi T.
- Journal Title
  
  Mol Reprod Dev
  
  Volume: - Issue: 4 Pages: 471-481
- DOI
  10.1002/mrd.23335
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K16014, KAKENHI-PROJECT-17H03938
[Journal Article] The relationship between embryonic development and the efficiency of target mutations in porcine endogenous retroviruses (PERVs) pol genes in porcine embryos2019
- Author(s)
  Hirata, M., Wittayarat, M., Hirano, T., Nguyen, TN., Le, AQ., Namula, Z., Fahrudin, M., Tanihara, F., Otoi, T.
- Journal Title
  
  Animals
  
  Volume: 9 Issue: 9 Pages: 593-593
- DOI
  10.3390/ani9090593
- NAID
  120006877872
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K12062, KAKENHI-PROJECT-17H03938
[Journal Article] Hypothermic storage of porcine zygotes in serum supplemented with chlorogenic acid.2019
- Author(s)
  Thi Nguyen N, Hirata M, Tanihara F, Hirano T, Le QA, Nii M, Otoi T.
- Journal Title
  
  Reprod Domest Anim.
  
  Volume: 54 Issue: 5 Pages: 750-755
- DOI
  10.1111/rda.13417
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03938, KAKENHI-PROJECT-17K19325
[Journal Article] Effects of Tris (hydroxymethyl) aminomethane on the quality of frozen-thawed boar spermatozoa.2019
- Author(s)
  Namula Z, Tanihara F, Wittayarat M, Hirata M, Nguyen NT, Hirano T, Le QA, Nii M, Otoi T.
- Journal Title
  
  Acta Vet Hung.
  
  Volume: 67 Issue: 1 Pages: 106-114
- DOI
  10.1556/004.2019.012
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03938, KAKENHI-PROJECT-17K19325
[Journal Article] Genome mutation after introduction of the gene editing by electroporation of Cas9 protein (GEEP) system in matured oocytes and putative zygotes.2019
- Author(s)
  Hirata M, Tanihara F, Wittayarat M, Hirano T, Nguyen NT, Le QA, Namula Z, Nii M, Otoi T.
- Journal Title
  
  In Vitro Cell Dev Biol Anim.
  
  Volume: 55 Issue: 4 Pages: 237-242
- DOI
  10.1007/s11626-019-00338-3
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03938, KAKENHI-PROJECT-17K19325
[Journal Article] Relationship among ovarian follicular status, developmental competence of oocytes, and anti-Müllerian hormone levels: A comparative study in Japanese wild boar crossbred gilts and Large White gilts.2019
- Author(s)
  Tanihara F, Hirata M, Iizuka S, Sairiki S, Nii M, Nguyen NT, Le QA, Hirano T, Otoi T.
- Journal Title
  
  Anim Sci J.
  
  Volume: 印刷中 Issue: 6 Pages: 712-718
- DOI
  10.1111/asj.13200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03938, KAKENHI-PROJECT-17K19325, KAKENHI-PROJECT-18K12062
[Journal Article] Genome mutation after the introduction of the gene editing by electroporation of Cas9 protein (GEEP) system into bovine putative zygotes.2019
- Author(s)
  Zhao Namula, Manita Wittayarat, Maki Hirata, Takayuki Hirano, Nhien Thi Nguyen, Quynh Anh Le, Mokhamad Fahrudin, Fuminori Tanihara, Takeshige Otoi
- Journal Title
  
  In Vitro Cellular & Developmental Biology- Animal
  
  Volume: 55 Issue: 8 Pages: 598-603
- DOI
  10.1007/s11626-019-00385-w
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03938
[Journal Article] Effects of concentration of CRISPR/Cas9 components on genetic mosaicism in cytoplasmic microinjected porcine embryos2019
- Author(s)
  Tanihara F, Hirata M, Nguyen NT, LE QA, Hirano T, Otoi T.
- Journal Title
  
  J. Reprod. Dev.
  
  Volume: 65 Issue: 3 Pages: 209-214
- DOI
  10.1262/jrd.2018-116
- NAID
  130007662977
- ISSN
  0916-8818, 1348-4400
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03938, KAKENHI-PROJECT-18K12062
[Journal Article] Effects of chlorogenic acid (CGA) supplementation during in vitro maturation culture on the development and quality of porcine embryos with electroporation treatment after in vitro fertilization.2018
- Author(s)
  Nguyen TV, Wittayarat M, Do LTK, Nguyen TV, Nii M, Namula Z, Kunihara T, Tanihara F, Hirata M, Otoi T.
- Journal Title
  
  Anim Sci J.
  
  Volume: 89 Issue: 8 Pages: 1207-1213
- DOI
  10.1111/asj.13049
- NAID
  120007099365
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03938, KAKENHI-PROJECT-17K19325
[Journal Article] Effects of chlorogenic acid and caffeic acid on the quality of frozen-thawed boar sperm.2018
- Author(s)
  Namula Z, Hirata M, Wittayarat M, Tanihara F, Thi Nguyen N, Hirano T, Nii M, Otoi T.
- Journal Title
  
  Reprod Domest Anim.
  
  Volume: 53 Issue: 6 Pages: 1600-1604
- DOI
  10.1111/rda.13288
- NAID
  120007099363
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03938, KAKENHI-PROJECT-17K19325
[Journal Article] Follicular development of canine ovaries stimulated by a combination treatment of eCG and hCG.2018
- Author(s)
  Hirata M, Tanihara F, Taniguchi M, Takagi M, Terazono T, Otoi T.
- Journal Title
  
  Vet Med Sci.
  
  Volume: 4 Issue: 4 Pages: 333-340
- DOI
  10.1002/vms3.121
- NAID
  120007042438
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03938
[Journal Article] Effects of Antifreeze Protein Supplementation on the Development of Porcine Morulae Stored at Hypothermic Temperatures.2018
- Author(s)
  Nguyen TV, Tanihara F, Hirata M, Hirano T, Nishio K, Kim Do LT, Nguyen TV, Nii M, Otoi T.
- Journal Title
  
  Cryo Letters.
  
  Volume: 39 Pages: 131-136
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03938
[Journal Article] Effects of Antifreeze Protein Supplementation on the Development of Porcine Morulae Stored at Hypothermic Temperatures.2018
- Author(s)
  Nguyen TV, Tanihara F, Hirata M, Hirano T, Nishio K, Kim Do LT, Nguyen TV, Nii M, Otoi T.
- Journal Title
  
  Cryo Letters.
  
  Volume: 39 Pages: 131-136
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19325
[Journal Article] Effects of voltage strength during electroporation on the development and quality of in vitro-produced porcine embryos.2018
- Author(s)
  Nishio K, Tanihara F, Nguyen TV, Kunihara T, Nii M, Hirata M, Takemoto T, Otoi T.
- Journal Title
  
  Reprod Domest Anim.
  
  Volume: 53 Issue: 2 Pages: 313-318
- DOI
  10.1111/rda.13106
- NAID
  120007099364
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03938, KAKENHI-PROJECT-18KT0024
[Journal Article] Generation of PDX-1 mutant porcine blastocysts by introducing CRISPR/Cas9-system into porcine zygotes via electroporation2018
- Author(s)
  Tanihara Fuminori、Hirata Maki、Nguyen Nhien T.、Le Quynh A.、Hirano Takayuki、Takemoto Tatsuya、Nakai Michiko、Fuchimoto Dai-ichiro、Otoi Takeshige
- Journal Title
  
  Animal Science Journal
  
  Volume: 90 Issue: 1 Pages: 55-61
- DOI
  10.1111/asj.13129
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03607, KAKENHI-PROJECT-17H03938, KAKENHI-PROJECT-18KT0024
[Patent] 遺伝子改変ブタ、遺伝子改変ブタの作出方法、及び創薬支援方法2023
- Inventor(s)
  谷原史倫、花園豊、本多新、黒尾誠
- Industrial Property Rights Holder
  谷原史倫、花園豊、本多新、黒尾誠
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2023-123204
- Filing Date
  2023
- Data Source
  KAKENHI-PROJECT-23K23805
[Presentation] Effects of CRISPR/Cas9-mediated gene targeting of porcine endogenous retrovirus on the developmental competence of porcine embryos.2019
- Author(s)
  Hirata, M., Tanihara, F., Nguyen, T.N., Le A.Q,, Hirano, T. and Otoi T.
- Organizer
  15th Transgenic Technology Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03938
[Presentation] ブタ体外受精卵におけるCRISPR/Cas9システムを用いた複数遺伝子の同時改変2019
- Author(s)
  1.平田真樹、谷原史倫、Nhien Thi Nguyen、Quynh Anh Le、平野隆之、音井威重
- Organizer
  第7回日本先進医工学ブタ研究会
- Data Source
  KAKENHI-PROJECT-18K12062
[Presentation] Effects of CRISPR/Cas9-mediated gene targeting of porcine endogenous retrovirus on the developmental competence of porcine embryos2019
- Author(s)
  Hirata, M., Tanihara, F., Nguyen, TN., Le, AQ., Hirano, T., Otoi, T.
- Organizer
  The 15th Transgenic Technology Meeting (TT2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K12062
[Presentation] Effect of Cas9 protein levels on genomic mutations using the gene editing by electroporation of Cas9 protein (GEEP) system in putative zygotes.2019
- Author(s)
  Le A.Q,, Hirata, M., Tanihara, F., Nguyen, T.N., Hirano, T. and Otoi T.
- Organizer
  15th Transgenic Technology Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03938
[Presentation] エレクトロポレーションを用いたCRISPR/Cas9システムのブタ体外受精卵への導入によるCD163遺伝子改変ブタの作製2019
- Author(s)
  谷原史倫、平田真樹、Nguyen Thi Nhien、Quynh Anh Le、平野隆之、音井威重
- Organizer
  第162回日本獣医学会
- Data Source
  KAKENHI-PROJECT-17H03938
[Presentation] Efficiency of gene editing by electroporation of Cas9 protein (GEEP) to generate GGTA1-modified pigs.2019
- Author(s)
  Nguyen, T.N., Hirata, M., Tanihara, F., Le A.Q,, Hirano, T. and Otoi T.
- Organizer
  15th Transgenic Technology Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03938
[Presentation] Assessment of PDX-1-deficient pigs generated using the CRISPR/Cas9 system introduced into porcine zygotes via electroporation.2019
- Author(s)
  Tanihara, F., Hirata, M., Nguyen, T.N., Le A.Q,, Hirano, T. and Otoi T.
- Organizer
  15th Transgenic Technology Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03938
[Presentation] エレクトロポレーションを用いたCRISPR/Cas9システムのブタ体外受精卵への導入によるCD163遺伝子改変ブタの作製2019
- Author(s)
  谷原史倫、平田真樹、Nhien Thi Nguyen、Quynh Anh Le、平野隆之、音井威重
- Organizer
  第162回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-19K16014
[Presentation] ゲノム編集によるTP53遺伝子改変ブタの作製と表現型の解析2018
- Author(s)
  谷原史倫, 平田真樹, NGUYEN NHIEN THI, LE ANH QUYNH, 平野隆之, 竹本龍也, 中井美智子, 淵本大一郎, 音井威重
- Organizer
  第6回日本先進医工学ブタ研究会
- Data Source
  KAKENHI-PROJECT-17K19325
[Presentation] ブタ内在性レトロウイルス遺伝子を標的としたゲノム編集が胚発育能に及ぼす影響2018
- Author(s)
  谷原史倫, 平田真樹, NGUYEN NHIEN THI, 平野隆之, 音井威重
- Organizer
  日本ゲノム編集学会第3回大会
- Data Source
  KAKENHI-PROJECT-17K19325
[Presentation] Concentration of CRISPR/Cas9 components effects on genetic mosaicism of cytoplasmic microinjected porcine embryos2018
- Author(s)
  Le Anh Quynh, Fuminori Tanihara, Maki Hirata, Nguyen Thi Nhien, Takayuki Hirano and Takeshige Otoi
- Organizer
  第6回日本先進医工学ブタ研究会
- Data Source
  KAKENHI-PROJECT-17K19325
[Presentation] ゲノム編集によるTP53遺伝子改変ブタの作製と表現型の解析2018
- Author(s)
  谷原史倫, 平田真樹, Nguyen Thi Nhien, Le Anh Quynh, 平野隆之, 竹本龍也, 中井美智子, 淵本大一郎, 音井威重
- Organizer
  第6回日本先進医工学ブタ研究会
- Data Source
  KAKENHI-PROJECT-17H03938
[Presentation] ブタにおける受精前後でのゲノム編集が胚盤胞の変異導入効率に及ぼす影響,2018
- Author(s)
  平田真樹, 谷原史倫, 平野隆之, Nguyen Thi Nhien, Le Anh Quynh, 新居雅宏, 音井威重
- Organizer
  第6回日本先進医工学ブタ研究会
- Data Source
  KAKENHI-PROJECT-17H03938
[Presentation] ブタにおけるCrispr/Cas9システムを使用したゲノム編集効率化についての検討2018
- Author(s)
  平田真樹、谷原史倫、Nhien Thi Nguyen、Zhao Namula、音井威重
- Organizer
  日本ゲノム編集学会第3回大会
- Data Source
  KAKENHI-PROJECT-18K12062
[Presentation] Modification of SALL1 gene via CRISPR/Cas9-mediated gene editing introduced into porcine zygotes by electroporation2018
- Author(s)
  Fuminori Tanihara, Tatsuya Takemoto, Maki Hirata, N Nguyen Thi, Toshiki Kunihara, R Nishinakamura and Takeshige Otoi
- Organizer
  The 3rd International symposium on Stem Cell Traits and Developmental Sys
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19325
[Presentation] Concentration of CRISPR/Cas9 components effects on genetic mosaicism of cytoplasmic microinjected porcine embryos2018
- Author(s)
  Le Anh Quynh, Fuminori Tanihara, Maki Hirata, Nguyen Thi Nhien, Takayuki Hirano and Takeshige Otoi
- Organizer
  第6回日本先進医工学ブタ研究会
- Data Source
  KAKENHI-PROJECT-17H03938
[Presentation] ブタ体外受精卵におけるCrispr/Cas9システムを使用したゲノム編集の効率2018
- Author(s)
  平田真樹, 谷原史倫, NGUYEN NHIEN THI, Namula Zhao, 音井威重
- Organizer
  日本ゲノム編集学会第3回大会
- Data Source
  KAKENHI-PROJECT-17K19325
[Presentation] ブタ体外受精卵におけるCrispr/Cas9システムを使用したゲノム編集の効率.2018
- Author(s)
  平田真樹、谷原史倫、Nhien Thi Nguyen、Zhao Namula、音井威重
- Organizer
  第3回ゲノム編集学会
- Data Source
  KAKENHI-PROJECT-17H03938
[Presentation] Hypothermic storage of porcine zygotes in serum supplemented with chlorogenic acid2018
- Author(s)
  Nguyen Thi Nhien, Fuminori Tanihara, Maki Hirata, Takayuki Hirano, Le Anh Quynh, Masahiro Nii and Takeshige Otoi
- Organizer
  第6回日本先進医工学ブタ研究会
- Data Source
  KAKENHI-PROJECT-17H03938
[Presentation] ブタにおける受精前後でのゲノム編集が胚盤胞の変異導入効率に及ぼす影響2018
- Author(s)
  平田真樹, 谷原史倫, 平野隆之, NGUYEN NHIEN THI, LE ANH QUYNH, 新居雅宏, 音井威重
- Organizer
  第6回日本先進医工学ブタ研究会
- Data Source
  KAKENHI-PROJECT-17K19325
[Presentation] ブタ内在性レトロウイルス遺伝子を標的としたゲノム編集が胚発育能に及ぼす影響2018
- Author(s)
  谷原史倫、平田真樹、Nguyen Thi Nhien、平野隆之、音井威重
- Organizer
  第3回ゲノム編集学会
- Data Source
  KAKENHI-PROJECT-17H03938
[Presentation] Modification of SALL1 gene via CRISPR/Cas9-mediated gene editing introduced into porcine zygotes by electroporation2018
- Author(s)
  Tanihara, F., Takemoto, T., Hirata, M., Nguyen, T.V., Kunihara,T. Nishinakamura, R. and Otoi, T.
- Organizer
  The 3rd International symposium on Stem Cell Traits and Developmental Systems
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03938
[Presentation] Hypothermic storage of porcine zygotes in serum supplemented with chlorogenic acid2018
- Author(s)
  Nguyen Thi Nhien, Fuminori Tanihara, Maki Hirata, Takayuki Hirano, Le Anh Quynh, 新居雅宏 and Takeshige Otoi
- Organizer
  第6回日本先進医工学ブタ研究会
- Data Source
  KAKENHI-PROJECT-17K19325
[Presentation] ブタにおける成熟卵および1細胞期胚段階でのゲノム編集が胚盤胞の変異導入効率に及ぼす影響2018
- Author(s)
  平田真樹、谷原史倫、Manita Wittayarat、Nhien Thi Nguyen、 Le Anh Quynh、Zhao Namula、新居雅宏、音井威重
- Organizer
  第6回日本先進医工学ブタ研究会
- Data Source
  KAKENHI-PROJECT-18K12062
[Presentation] Effects of voltage strength on development and quality of electroporated porcine embryos.2017
- Author(s)
  Nishio, K., Tanihara, F., Nguyen, T.V., Kunihara,T. and Otoi, T.
- Organizer
  2017 Transgenic Technology Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19325

1. OTOI Takeshige (30311814)

# of Collaborated Projects: 5 results

# of Collaborated Products: 47 results
2. HIRATA Maki (10815583)

# of Collaborated Projects: 3 results

# of Collaborated Products: 16 results
3. 竹本龍也 (30443899)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
4. TOBA Hiroaki (40403745)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 香月康宏 (90403401)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 川上行奎 (00596249)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 河北直也 (60522266)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 森本雅美 (90563817)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 下田宙 (40719887)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 田中良法 (00747933)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 本多新 (10373367)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 岩津好隆 (40424014)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 佐久間哲史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tanihara Fuminori 谷原 史倫

Research Projects

Research Products

Co-Researchers

Development of animal model for kidney-specific spontaneous tumours

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慢性腎臓病に起因する健康寿命減衰をリン（CPP）の除去により防ぎ止める橋渡し研究Principal Investigator

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Generation of African Swine Fever virus-resistant pigs by applying the concept of gene editing technologyPrincipal Investigator

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Generation of a pig model for the diabetic nephropathy using gene editing technologyPrincipal Investigator

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Production of immunodeficient micro-mini pig using genome editing technology.

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The role of p53 during airway and lung injury, repair and regeneration using TP53-mutant porcine

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Production of pigs for safe xenotransplantation by controlling infectious porcine endogenous retrovirus (PERV)

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Production of genetically modified pigs by combined techniques of chromosome engineering and genome editing

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[Journal Article] GHR-mutant pig derived from domestic pig and microminipig hybrid zygotes using CRISPR/Cas9 system2023

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[Journal Article] Pigs with an INS point mutation derived from zygotes electroporated with CRISPR/Cas9 and ssODN2023

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[Journal Article] Mosaic TP53 Mutation on Tumour Development in Pigs: A Case Study2023

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[Journal Article] Viability and developmental potential of porcine blastocysts preserved for short term in a chemically defined medium at ambient temperature2022

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[Journal Article] One-Step Generation of Multiple Gene-Edited Pigs by Electroporation of the CRISPR/Cas9 System into Zygotes to Reduce Xenoantigen Biosynthesis2021

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NAID

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[Journal Article] Introduction of a point mutation in the KRAS gene of in vitro fertilized porcine zygotes via electroporation of the CRISPR/Cas9 system with single-stranded oligodeoxynucleotides.2021

Author(s)

Tanihara Fuminori 谷原史倫

[Journal Article] Relationship among ovarian follicular status, developmental competence of oocytes, and anti-Müllerian hormone levels: A comparative study in Japanese wild boar crossbred gilts and Large White gilts.2019