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Okato Atsushi  岡東 篤

… Alternative Names

岡東 篤  オカトウ アツシ

OKATO ATSUSHI  岡東 篤

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Researcher Number 90756719
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-4207-9744
Affiliation (Current) 2025: 国立研究開発法人量子科学技術研究開発機構, QST病院 治療診断部, 医長
Affiliation (based on the past Project Information) *help 2021 – 2023: 帝京大学, 医学部, 助教
2017 – 2018: 千葉大学, 医学部附属病院, 医員
Review Section/Research Field
Principal Investigator
Basic Section 50020:Tumor diagnostics and therapeutics-related / 0901:Oncology and related fields / Urology
Except Principal Investigator
Urology
Keywords
Principal Investigator
FGFR3 / FGFR3変異 / 腫瘍免疫環境 / 免疫チェックポイント阻害薬 / FGFR阻害薬 / 遺伝子改変モデルマウス / 膀胱癌 / FGFR3遺伝子変異 / 腎細胞癌 / 治療抵抗性腎癌 / マイクロRNA … More
Except Principal Investigator
… More 癌遺伝子 / 癌抑制遺伝子 / 去勢抵抗性前立腺癌 / 細胞外マトリックス / 前立腺癌 / マイクロRNA Less
  • Research Projects

    (4 results)
  • Research Products

    (20 results)
  • Co-Researchers

    (8 People)
  •  Elucidation of the tumor microenvironment of FGFR3-mutant bladder cancer using genetically engineered murine modelsPrincipal Investigator

    • Principal Investigator
      岡東 篤
    • Project Period (FY)
      2023 – 2027
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Teikyo University
  •  FGFR3遺伝子改変モデル膀胱癌における腫瘍微小環境の解明と新規治療への応用Principal Investigator

    • Principal Investigator
      岡東 篤
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Review Section
      0901:Oncology and related fields
    • Research Institution
      Teikyo University
  •  Identifying molecular pathogenesis of advanced renal cell carcinoma based on microRNA expressionPrincipal Investigator

    • Principal Investigator
      Okato Atsushi
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Urology
    • Research Institution
      Chiba University
  •  Elucidation of extracellular matrix molecular pathway regulated by metastasis-suppressing microRNAs in prostate cancer.

    • Principal Investigator
      KATO MAYUKO
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Urology
    • Research Institution
      Chiba University

All 2024 2018 2017 2016 Other

All Journal Article Presentation Other

  • [Journal Article] FGFR inhibition augments anti?PD-1 efficacy in murine FGFR3-mutant bladder cancer by abrogating immunosuppression2024

    • Author(s)
      Okato Atsushi、Utsumi Takanobu、Kim William Y.
    • Journal Title

      Journal of Clinical Investigation

      Volume: 134 Issue: 2

    • DOI

      10.1172/jci169241

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K14628, KAKENHI-PROJECT-21K20814
  • [Journal Article] Dual strands of the miR-223 duplex (miR-223-5p and miR-223-3p) inhibit cancer cell aggressiveness: targeted genes are involved in bladder cancer pathogenesis2018

    • Author(s)
      Sugawara Sho、Yamada Yasutaka、Arai Takayuki、Okato Atsushi、Idichi Tetsuya、Kato Mayuko、Koshizuka Keiichi、Ichikawa Tomohiko、Seki Naohiko
    • Journal Title

      J Hum Genet

      Volume: 印刷中 Issue: 5 Pages: 657-668

    • DOI

      10.1038/s10038-018-0437-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H05462, KAKENHI-PROJECT-17K16778
  • [Journal Article] Regulation of metastasis-promoting LOXL2 gene expression by antitumor microRNAs in prostate cancer.2017

    • Author(s)
      Kato M, Kurozumi A, Goto Y, Matsushita R, Okato A, Nishikawa R, Fukumoto I, Koshizuka K, Ichikawa T, Seki N.
    • Journal Title

      Journal of Human genetics

      Volume: 62 Pages: 123-132

    • NAID

      40021036352

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-16K20125
  • [Journal Article] Antitumor miR-150-5p and miR-150-3p inhibit cancer cell aggressiveness by targeting SPOCK1 in head and neck squamous cell carcinoma.2017

    • Author(s)
      Koshizuka, K., T. Hanazawa, N. Kikkawa, K. Katada, A. Okato, T. Arai, T. Idichi, Y. Osako, Y. Okamoto and N. Seki
    • Journal Title

      Auris Nasus Larynx

      Volume: - Issue: 4 Pages: 854-865

    • DOI

      10.1016/j.anl.2017.11.019

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K16893, KAKENHI-PROJECT-17K11375, KAKENHI-PROJECT-18K09338, KAKENHI-PROJECT-17K16778
  • [Journal Article] Regulation of E3 ubiquitin ligase-1 (WWP1) by microRNA-452 inhibits cancer cell migration and invasion in prostate cancer.2016

    • Author(s)
      Goto Y, Kojima S, Kurozumi A, Kato M, Okato A, Matsushita R, Ichikawa T, Seki N.
    • Journal Title

      British journal of cancer

      Volume: 114 Pages: 1135-44

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K20125
  • [Journal Article] Direct regulation of LAMP1 by tumor-suppressive microRNA-320a in prostate cancer2016

    • Author(s)
      Okato A, Goto Y, Kurozumi A, Kato M, Kojima S, Matsushita R, Yonemori M, Miyamoto K, Ichikawa T, Seki N.
    • Journal Title

      International journal of oncology

      Volume: 49 Pages: 111-22

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-16K20125
  • [Presentation] 腎細胞癌・マイクロRNA発現プロファイルに基づく、機能性RNAネットワークの探索2018

    • Author(s)
      岡東 篤
    • Organizer
      第106回日本泌尿器科学会総会
    • Data Source
      KAKENHI-PROJECT-17K16778
  • [Presentation] Dual-strand tumor-suppressor microRNA-145 (miR-145-5p and miR-145-3p) are involved in castration-resistant prostate cancer pathogenesis2017

    • Author(s)
      Mayuko Kato, Akira Kurozumi, Yusuke Goto, Nijiro Nohata, Takayuki Arai, Atsushi Okato, Keiichi Koshizuka, Satoko Kojima, Tomohiko Ichikawa, Naohiko Seki.
    • Organizer
      American Association for Cancer Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K20125
  • [Presentation] Tumor-suppressive microRNAs (miR-26a/b, miR-29a/b/c and miR-218) concertedly regulate metastasis-promoting LOXL2 in prostate cancer2017

    • Author(s)
      Mayuko Kato, Akira Kurozumi, Yusuke Goto, Ryosuke Matsushita, Ichiro Fukumoto, Atsushi Okato, Rika Nishikawa, Shinichi Sakamoto, Tomohiko Ichikawa, Naohiko Seki
    • Organizer
      American Association for Cancer Research Annual meeting 2016
    • Place of Presentation
      Ernest N. Morial Convention Center New Orleans, Louisiana, USA
    • Year and Date
      2017-04-18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K20125
  • [Presentation] The microRNA expression signature of patients with renal cell carcinoma : tumor-suppressive miR-149-5p targeting FOXM12017

    • Author(s)
      Okato Atsushi
    • Organizer
      2017 AUA Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K16778
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  • 1.  KATO MAYUKO (80733857)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 2.  ICHIKAWA TOMOHIKO (20241953)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 3.  SEKI NAOHIKO (50345013)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results
  • 4.  KOJIMA SATOKO (10345019)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 5.  ARAI TAKAYUKI (40793055)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 6.  KOSHIZUKA KEIICHI (00791609)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 7.  YAMADA YASUTAKA (30814595)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  SUGAWARA SYO (70815290)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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