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Yasuhara Takaaki  安原 崇哲

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安原 崇哲  ヤスハラ タカアキ

YASUHARA Takaaki  安原 崇哲

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Researcher Number 90757056
Other IDs
Affiliation (Current) 2020: 東京大学, 大学院医学系研究科(医学部), 助教
Affiliation (based on the past Project Information) *help 2020: 東京大学, 大学院医学系研究科(医学部), 助教
2018: 東京大学, 大学院医学系研究科(医学部), 助教
2016: 東京大学, 大学院医学系研究科(医学部), 助教
2015: 東京大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field
Principal Investigator
Tumor biology / Basic Section 63020:Radiation influence-related
Except Principal Investigator
Medium-sized Section 50:Oncology and related fields
Keywords
Principal Investigator
がん / 細胞機能ネットワーク / Rad54B / 細胞周期 / E2Fファミリー / R-loop構造 / DNA二重鎖切断 / DNA損傷シグナリング / DNA修復
Except Principal Investigator
発がん … More / DNA複製ストレス / ATR / ゲノム不安定性 / 染色体転座 / DNA二本鎖切断 / 転写共役型DNA修復 Less
  • Research Projects

    (4 results)
  • Research Products

    (13 results)
  • Co-Researchers

    (5 People)
  •  遺伝子領域間に引き起こされる転写共役型染色体転座経路の解明Ongoing

    • Principal Investigator
      柴田 淳史
    • Project Period (FY)
      2020 – 2021
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 50:Oncology and related fields
    • Research Institution
      Gunma University
  •  The roles of R-loop structure in DNA damage signaling and genomePrincipal InvestigatorOngoing

    • Principal Investigator
      安原 崇哲
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 63020:Radiation influence-related
    • Research Institution
      The University of Tokyo
  •  Elucidation of the mechanism underlying DNA replication stress response regulating genomic instabilityOngoing

    • Principal Investigator
      塩谷 文章
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
    • Review Section
      Medium-sized Section 50:Oncology and related fields
    • Research Institution
      National Cancer Center Japan
  •  Mechanism for cancer-related upregulation of the Rad54B-mediated cellular function networkPrincipal Investigator

    • Principal Investigator
      YASUHARA Takaaki
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Tumor biology
    • Research Institution
      The University of Tokyo

All 2019 2018 2016 2015

All Journal Article Presentation

  • [Journal Article] Base excision repair regulates PD-L1 expression in cancer cells2019

    • Author(s)
      Permata, MBT, Hagiwara, Y., Sato, H., Yasuhara, T., Oike, T., Gondhowiardjo, S., Held, KD, Nakano, T., and Shibata, A.
    • Journal Title

      Oncogene

      Volume: 印刷中

    • DOI

      10.1038/s41388-019-0733-6

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K18191, KAKENHI-PROJECT-17K16420
  • [Journal Article] The role of R-loops in transcription-associated DNA double-strand break repair2019

    • Author(s)
      Kato Reona、Miyagawa Kiyoshi、Yasuhara Takaaki
    • Journal Title

      Molecular & Cellular Oncology

      Volume: 6 Pages: 1542244-1542244

    • DOI

      10.1080/23723556.2018.1542244

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K18191
  • [Journal Article] Elucidation of the Mechanism Regulating Transcription Associated Dna Double Strand Break Repair and Its Pathway2019

    • Author(s)
      Shibata Atsushi、Yasuhara Takaaki
    • Journal Title

      Impact

      Volume: 2019 Pages: 50-51

    • DOI

      10.21820/23987073.2019.3.50

    • Data Source
      KAKENHI-PROJECT-18K18191
  • [Journal Article] Human Rad52 Promotes XPG-Mediated R-loop Processing to Initiate Transcription-Associated Homologous Recombination Repair.2018

    • Author(s)
      Yasuhara Takaaki、Kato Reona、Hagiwara Yoshihiko、Shiotani Bunsyo、Yamauchi Motohiro、Nakada Shinichiro、Shibata Atsushi、Miyagawa Kiyoshi
    • Journal Title

      Cell

      Volume: 175 Pages: 558-570

    • DOI

      10.1016/j.cell.2018.08.056

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K18191, KAKENHI-PROJECT-18KK0235, KAKENHI-PROJECT-18H03378, KAKENHI-PROJECT-16K12602, KAKENHI-PROJECT-26241014, KAKENHI-PROJECT-17H04713
  • [Journal Article] 細胞機能間ネットワークを標的としたがん治療戦略2016

    • Author(s)
      安原 崇哲、宮川 清
    • Journal Title

      放射線生物研究

      Volume: 51 Pages: 127-139

    • NAID

      40020903961

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H06146
  • [Presentation] Rad52 promotes XPG-mediated R-loop processing to initiate transcription-associated homologous recombination repair2019

    • Author(s)
      Takaaki Yasuhara、Kato Reona、Shibata Atsushi、Miyagawa Kiyoshi
    • Organizer
      Keystone Symposia - Genomic Instability and DNA Repair
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K18191
  • [Presentation] Rad52 promotes XPG-mediated R-loop processing to initiate transcription-associated homologous recombination repair2018

    • Author(s)
      Takaaki Yasuhara、Kato Reona、Shibata Atsushi、Miyagawa Kiyoshi
    • Organizer
      Abcam meeting - Mechanisms of Recombination 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K18191
  • [Presentation] Rad54Bを介した細胞機能ネットワークの解析によるがん発生機構の解明2016

    • Author(s)
      安原 崇哲
    • Organizer
      平成28年東京RBC新春放談会
    • Place of Presentation
      東京大学(東京都文京区)
    • Year and Date
      2016-02-13
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H06146
  • [Presentation] The Rad54B-p53 axis limits the strength of DNA damage checkpoint2016

    • Author(s)
      Takaaki Yasuhara
    • Organizer
      日本放射線影響学会第59回大会
    • Place of Presentation
      広島市
    • Year and Date
      2016-10-26
    • Data Source
      KAKENHI-PROJECT-15H06146
  • [Presentation] The Rad54B-p53 axis limits the strength of DNA damage checkpoint2016

    • Author(s)
      Takaaki Yasuhara
    • Organizer
      第 75 回日本癌学会学術総会
    • Place of Presentation
      横浜市
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-15H06146
  • [Presentation] 細胞機能間ネットワークを標的とした新たながん治療戦略2016

    • Author(s)
      安原 崇哲
    • Organizer
      群大Genome Damage Discussion Group 公開セミナー
    • Place of Presentation
      群馬大学
    • Year and Date
      2016-05-31
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H06146
  • [Presentation] The novel mechanism linking cell cycle regulation to cancer development2015

    • Author(s)
      安原 崇哲
    • Organizer
      第38回日本分子生物学会年会
    • Place of Presentation
      神戸ポートピアホテル(兵庫県神戸市)
    • Year and Date
      2015-12-02
    • Data Source
      KAKENHI-PROJECT-15H06146
  • [Presentation] がん発生の基盤となる分子メカニズムを探る ー DNA損傷下における細胞周期の新たな制御因子 ー2015

    • Author(s)
      安原 崇哲
    • Organizer
      第10回原子炉研コロキウム
    • Place of Presentation
      東京工業大学原子炉工学研究所(東京都目黒区)
    • Year and Date
      2015-12-18
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H06146
  • 1.  塩谷 文章 (10627665)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 2.  中田 慎一郎 (70548528)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 3.  柴田 淳史 (30707633)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 4.  山内 基弘 (60437910)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  佐藤 浩央
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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