Yasuhara Takaaki 安原崇哲

… Alternative Names

Researcher Number	90757056
Other IDs
Affiliation (Current)	2020: 東京大学, 大学院医学系研究科(医学部), 助教
Affiliation (based on the past Project Information) *help	2020: 東京大学, 大学院医学系研究科(医学部), 助教 2018: 東京大学, 大学院医学系研究科(医学部), 助教 2016: 東京大学, 大学院医学系研究科(医学部), 助教 2015: 東京大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field	Principal Investigator Tumor biology / Basic Section 63020:Radiation influence-related Except Principal Investigator Medium-sized Section 50:Oncology and related fields
Keywords	Principal Investigator がん / 細胞機能ネットワーク / Rad54B / 細胞周期 / E2Fファミリー / R-loop構造 / DNA二重鎖切断 / DNA損傷シグナリング / DNA修復 Except Principal Investigator 発がん … More

遺伝子領域間に引き起こされる転写共役型染色体転座経路の解明Ongoing
- Principal Investigator
  
  柴田淳史
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  Gunma University
The roles of R-loop structure in DNA damage signaling and genomePrincipal InvestigatorOngoing
- Principal Investigator
  
  安原崇哲
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 63020:Radiation influence-related
- Research Institution
  The University of Tokyo
Elucidation of the mechanism underlying DNA replication stress response regulating genomic instabilityOngoing
- Principal Investigator
  
  塩谷文章
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  National Cancer Center Japan
Mechanism for cancer-related upregulation of the Rad54B-mediated cellular function networkPrincipal Investigator
- Principal Investigator
  
  YASUHARA Takaaki
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Tumor biology
- Research Institution
  The University of Tokyo

All 2019 2018 2016 2015

All Journal Article Presentation

[Journal Article] Base excision repair regulates PD-L1 expression in cancer cells2019
- Author(s)
  Permata, MBT, Hagiwara, Y., Sato, H., Yasuhara, T., Oike, T., Gondhowiardjo, S., Held, KD, Nakano, T., and Shibata, A.
- Journal Title
  
  Oncogene
  
  Volume: 印刷中
- DOI
  10.1038/s41388-019-0733-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K18191, KAKENHI-PROJECT-17K16420
[Journal Article] The role of R-loops in transcription-associated DNA double-strand break repair2019
- Author(s)
  Kato Reona、Miyagawa Kiyoshi、Yasuhara Takaaki
- Journal Title
  
  Molecular & Cellular Oncology
  
  Volume: 6 Pages: 1542244-1542244
- DOI
  10.1080/23723556.2018.1542244
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K18191
[Journal Article] Elucidation of the Mechanism Regulating Transcription Associated Dna Double Strand Break Repair and Its Pathway2019
- Author(s)
  Shibata Atsushi、Yasuhara Takaaki
- Journal Title
  
  Impact
  
  Volume: 2019 Pages: 50-51
- DOI
  10.21820/23987073.2019.3.50
- Data Source
  KAKENHI-PROJECT-18K18191
[Journal Article] Human Rad52 Promotes XPG-Mediated R-loop Processing to Initiate Transcription-Associated Homologous Recombination Repair.2018
- Author(s)
  Yasuhara Takaaki、Kato Reona、Hagiwara Yoshihiko、Shiotani Bunsyo、Yamauchi Motohiro、Nakada Shinichiro、Shibata Atsushi、Miyagawa Kiyoshi
- Journal Title
  
  Cell
  
  Volume: 175 Pages: 558-570
- DOI
  10.1016/j.cell.2018.08.056
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K18191, KAKENHI-PROJECT-18KK0235, KAKENHI-PROJECT-18H03378, KAKENHI-PROJECT-16K12602, KAKENHI-PROJECT-26241014, KAKENHI-PROJECT-17H04713
[Journal Article] 細胞機能間ネットワークを標的としたがん治療戦略2016
- Author(s)
  安原崇哲、宮川清
- Journal Title
  
  放射線生物研究
  
  Volume: 51 Pages: 127-139
- NAID
  40020903961
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H06146
[Presentation] Rad52 promotes XPG-mediated R-loop processing to initiate transcription-associated homologous recombination repair2019
- Author(s)
  Takaaki Yasuhara、Kato Reona、Shibata Atsushi、Miyagawa Kiyoshi
- Organizer
  Keystone Symposia - Genomic Instability and DNA Repair
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K18191
[Presentation] Rad52 promotes XPG-mediated R-loop processing to initiate transcription-associated homologous recombination repair2018
- Author(s)
  Takaaki Yasuhara、Kato Reona、Shibata Atsushi、Miyagawa Kiyoshi
- Organizer
  Abcam meeting - Mechanisms of Recombination 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K18191
[Presentation] The Rad54B-p53 axis limits the strength of DNA damage checkpoint2016
- Author(s)
  Takaaki Yasuhara
- Organizer
  第 75 回日本癌学会学術総会
- Place of Presentation
  横浜市
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-15H06146
[Presentation] Rad54Bを介した細胞機能ネットワークの解析によるがん発生機構の解明2016
- Author(s)
  安原　崇哲
- Organizer
  平成28年東京RBC新春放談会
- Place of Presentation
  東京大学（東京都文京区）
- Year and Date
  2016-02-13
- Invited
- Data Source
  KAKENHI-PROJECT-15H06146
[Presentation] The Rad54B-p53 axis limits the strength of DNA damage checkpoint2016
- Author(s)
  Takaaki Yasuhara
- Organizer
  日本放射線影響学会第59回大会
- Place of Presentation
  広島市
- Year and Date
  2016-10-26
- Data Source
  KAKENHI-PROJECT-15H06146
[Presentation] 細胞機能間ネットワークを標的とした新たながん治療戦略2016
- Author(s)
  安原崇哲
- Organizer
  群大Genome Damage Discussion Group 公開セミナー
- Place of Presentation
  群馬大学
- Year and Date
  2016-05-31
- Invited
- Data Source
  KAKENHI-PROJECT-15H06146
[Presentation] がん発生の基盤となる分子メカニズムを探るー DNA損傷下における細胞周期の新たな制御因子ー2015
- Author(s)
  安原　崇哲
- Organizer
  第10回原子炉研コロキウム
- Place of Presentation
  東京工業大学原子炉工学研究所（東京都目黒区）
- Year and Date
  2015-12-18
- Invited
- Data Source
  KAKENHI-PROJECT-15H06146
[Presentation] The novel mechanism linking cell cycle regulation to cancer development2015
- Author(s)
  安原　崇哲
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸ポートピアホテル（兵庫県神戸市）
- Year and Date
  2015-12-02
- Data Source
  KAKENHI-PROJECT-15H06146

1. 塩谷文章 (10627665)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. 中田慎一郎 (70548528)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. 柴田淳史 (30707633)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 山内基弘 (60437910)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 佐藤浩央

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yasuhara Takaaki 安原 崇哲

安原 崇哲 ヤスハラ タカアキ

YASUHARA Takaaki 安原 崇哲

Research Projects

Research Products

Co-Researchers

遺伝子領域間に引き起こされる転写共役型染色体転座経路の解明Ongoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The roles of R-loop structure in DNA damage signaling and genomePrincipal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the mechanism underlying DNA replication stress response regulating genomic instabilityOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanism for cancer-related upregulation of the Rad54B-mediated cellular function networkPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Base excision repair regulates PD-L1 expression in cancer cells2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The role of R-loops in transcription-associated DNA double-strand break repair2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Elucidation of the Mechanism Regulating Transcription Associated Dna Double Strand Break Repair and Its Pathway2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Human Rad52 Promotes XPG-Mediated R-loop Processing to Initiate Transcription-Associated Homologous Recombination Repair.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 細胞機能間ネットワークを標的としたがん治療戦略2016

Author(s)

Journal Title

NAID

Data Source

[Presentation] Rad52 promotes XPG-mediated R-loop processing to initiate transcription-associated homologous recombination repair2019

Author(s)

Organizer

Data Source

[Presentation] Rad52 promotes XPG-mediated R-loop processing to initiate transcription-associated homologous recombination repair2018

Author(s)

Organizer

Data Source

[Presentation] The Rad54B-p53 axis limits the strength of DNA damage checkpoint2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Rad54Bを介した細胞機能ネットワークの解析によるがん発生機構の解明2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] The Rad54B-p53 axis limits the strength of DNA damage checkpoint2016

Author(s)

Organizer

Place of Presentation

Year and Date

Yasuhara Takaaki 安原崇哲

安原崇哲ヤスハラタカアキ

YASUHARA Takaaki 安原崇哲

[Presentation] がん発生の基盤となる分子メカニズムを探るー DNA損傷下における細胞周期の新たな制御因子ー2015