Yasuhara Takaaki 安原崇哲

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YASUHARA Takaaki 安原崇哲

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Researcher Number	90757056
Other IDs	https://orcid.org/0000-0002-6719-5709
Affiliation (Current)	2025: 京都大学, 生命科学研究科, 教授
Affiliation (based on the past Project Information) *help	2023 – 2025: 京都大学, 生命科学研究科, 教授 2018 – 2022: 東京大学, 大学院医学系研究科(医学部), 助教 2016: 東京大学, 大学院医学系研究科(医学部), 助教 2015: 東京大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field	Principal Investigator Basic Section 63020:Radiation influence-related / Transformative Research Areas, Section (III) / Medium-sized Section 44:Biology at cellular to organismal levels, and related fields / Tumor biology Except Principal Investigator Medium-sized Section 50:Oncology and related fields / Basic Section 63020:Radiation influence-related
Keywords	Principal Investigator 転写 / がんゲノム異常 / 染色体転座 / 凝集体 / DNA修復 / 相置換 / 修復 / 染色体異常 / RAP80 / ゲノム安定性 … More / R-loop / DSB修復 / マッピング法 / 核内位置空間 / ゲノム脆弱部位 / 液―液相分離 / RNA結合タンパク質 / 遺伝子発現誘導 / ゲノム構造変換 / 核小体 / ゲノム異常 / DNA損傷シグナリング / DNA二重鎖切断 / R-loop構造 / E2Fファミリー / 細胞周期 / Rad54B / 細胞機能ネットワーク / がん … More Except Principal Investigator 染色体転座 / 放射線 / 発がん / 転写 / DSB修復 / クロマチン / HR / NHEJ / DNA修復 / 転写共役型DNA修復 / DNA切断 / DNA二本鎖切断 / 肺がん / KRAS / PrimPol / ATR / ヘテロクロマチン / RNA転写 / ゲノム不安定性 / DNA複製ストレス Less

Genomic instability caused by the phase transition-induced abnormality in transcription-repair couplingPrincipal Investigator
- Principal Investigator
  
  安原崇哲
- Project Period (FY)
  2025 – 2029
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 44:Biology at cellular to organismal levels, and related fields
- Research Institution
  Kyoto University
Genome instability induced by spatial positions in the nucleusPrincipal Investigator
- Principal Investigator
  
  安原崇哲
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Kyoto University
A strategy to transform genomic organization and change the gene expression pattern via controlling nucleolar condensatesPrincipal Investigator
- Principal Investigator
  
  安原崇哲
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Kyoto University
  The University of Tokyo
全ゲノム領域に共通した正確なDNA修復を保証するDSB修復経路選択機構の研究
- Principal Investigator
  
  柴田淳史
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 63020:Radiation influence-related
- Research Institution
  Keio University
  Gunma University
Investigation of the new factors regulating transcription- associated DNA double-strand break repairPrincipal Investigator
- Principal Investigator
  
  安原崇哲
- Project Period (FY)
  2021 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 63020:Radiation influence-related
- Research Institution
  Kyoto University
  The University of Tokyo
Elucidation of transcription-coupled chromosomal translocation pathways between gene loci
- Principal Investigator
  
  Shibata Atsushi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  Gunma University
The mechanism for gene fusion mediated by condensatesPrincipal Investigator
- Principal Investigator
  
  Yasuhara Takaaki
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (A))
- Review Section
  
  Basic Section 63020:Radiation influence-related
- Research Institution
  Kyoto University
  The University of Tokyo
The roles of R-loop structure in DNA damage signaling and genomePrincipal Investigator
- Principal Investigator
  
  Yasuhara Takaaki
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 63020:Radiation influence-related
- Research Institution
  The University of Tokyo
Elucidation of the mechanism underlying DNA replication stress response regulating genomic instability
- Principal Investigator
  
  Shiotani Bunsyo
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  National Cancer Center Japan
Mechanism for cancer-related upregulation of the Rad54B-mediated cellular function networkPrincipal Investigator
- Principal Investigator
  
  YASUHARA Takaaki
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Tumor biology
- Research Institution
  The University of Tokyo

All 2023 2022 2021 2020 2019 2018 2016 2015

All Journal Article Presentation

[Journal Article] An ATR-PrimPol pathway confers tolerance to oncogenic KRAS-induced and heterochromatin-associated replication stress2023
- Author(s)
  Igarashi Taichi、Mazevet Marianne、Yasuhara Takaaki、Yano Kimiyoshi、Mochizuki Akifumi、Nishino Makoto、Yoshida Tatsuya、Yoshida Yukihiro、Takamatsu Nobuhiko、Yoshimi Akihide、Shiraishi Kouya、Horinouchi Hidehito、Kohno Takashi、Hamamoto Ryuji、Adachi Jun、Zou Lee、Shiotani Bunsyo
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 4991-4991
- DOI
  10.1038/s41467-023-40578-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20KK0339, KAKENHI-PUBLICLY-22H05585, KAKENHI-PUBLICLY-23H04274, KAKENHI-PROJECT-21H04828, KAKENHI-PROJECT-23K21750, KAKENHI-PROJECT-23K24999
[Journal Article] Condensates induced by transcription inhibition localize active chromatin to nucleoli2022
- Author(s)
  Yasuhara Takaaki、Xing Yu-Hang、Bauer Nicholas C.、Lee Lukuo、Dong Rui、Yadav Tribhuwan、Soberman Roy J.、Rivera Miguel N.、Zou Lee
- Journal Title
  
  Molecular Cell
  
  Volume: 82 Issue: 15 Pages: 2738-2753
- DOI
  10.1016/j.molcel.2022.05.010
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20KK0339, KAKENHI-PROJECT-23K21750
[Journal Article] ゲノム安定性維持機構におけるarcRNA の役割2022
- Author(s)
  安原　崇哲
- Journal Title
  
  月刊「細胞」
  
  Volume: 54 Pages: 30-33
- Data Source
  KAKENHI-PROJECT-20KK0339
[Journal Article] ゲノム安定性維持機構におけるarcRNA の役割2022
- Author(s)
  安原　崇哲
- Journal Title
  
  月刊「細胞」
  
  Volume: 54 Pages: 30-33
- Data Source
  KAKENHI-PROJECT-23K21750
[Journal Article] RNA を介したゲノム安定性の維持機構2022
- Author(s)
  安原　崇哲
- Journal Title
  
  月刊「アグリバイオ」
  
  Volume: 6 Pages: 77-81
- Data Source
  KAKENHI-PUBLICLY-22H05585
[Journal Article] DNA damage promotes HLA class I presentation by stimulating a pioneer round of translation-associated antigen production2022
- Author(s)
  Uchihara Yuki、Permata Tiara Bunga Mayang、Sato Hiro、Kawabata-Iwakawa Reika、Katada Sayako、Gu Wenchao、Kakoti Sangeeta、Yamauchi Motohiro、Kato Reona、Gondhowiardjo Soehartati、Hosen Naoki、Yasuhara Takaaki、Shibata Atsushi
- Journal Title
  
  Molecular Cell
  
  Volume: 82 Issue: 14 Pages: 2557-2570.e7
- DOI
  10.1016/j.molcel.2022.04.030
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K17888, KAKENHI-PUBLICLY-21H05504, KAKENHI-PROJECT-20K06875, KAKENHI-PROJECT-20K21536, KAKENHI-PROJECT-23K21749
[Journal Article] RNA を介したゲノム安定性の維持機構2022
- Author(s)
  安原　崇哲
- Journal Title
  
  月刊「アグリバイオ」
  
  Volume: 6 Pages: 77-81
- Data Source
  KAKENHI-PROJECT-20KK0339
[Journal Article] Active RB causes visible changes in nuclear organization2022
- Author(s)
  Krishnan Badri、Yasuhara Takaaki、Rumde Purva、Stanzione Marcello、Lu Chenyue、Lee Hanjun、Lawrence Michael S.、Zou Lee、Nieman Linda T.、Sanidas Ioannis、Dyson Nicholas J.
- Journal Title
  
  Journal of Cell Biology
  
  Volume: 221 Issue: 3
- DOI
  10.1083/jcb.202102144
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20KK0339
[Journal Article] RAP80 suppresses the vulnerability of R-loops during DNA double-strand break repair2022
- Author(s)
  Yasuhara Takaaki、Kato Reona、Yamauchi Motohiro、Uchihara Yuki、Zou Lee、Miyagawa Kiyoshi、Shibata Atsushi
- Journal Title
  
  Cell Reports
  
  Volume: 38 Issue: 5 Pages: 110335-110335
- DOI
  10.1016/j.celrep.2022.110335
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04713, KAKENHI-PUBLICLY-20H04879, KAKENHI-PROJECT-20J12698, KAKENHI-PROJECT-20K21536, KAKENHI-PROJECT-21K17888, KAKENHI-PROJECT-20KK0339, KAKENHI-PUBLICLY-21H05504, KAKENHI-PROJECT-23K21749, KAKENHI-PROJECT-23K21750
[Journal Article] RNA を介したゲノム安定性の維持機構2022
- Author(s)
  安原　崇哲
- Journal Title
  
  月刊「アグリバイオ」
  
  Volume: 6 Pages: 77-81
- Data Source
  KAKENHI-PROJECT-23K21750
[Journal Article] Mechanism of chromosome rearrangement arising from single-strand breaks2021
- Author(s)
  Kot Palina、Yasuhara Takaaki、Shibata Atsushi、Hirakawa Miyako、Abe Yu、Yamauchi Motohiro、Matsuda Naoki
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 572 Pages: 191-196
- DOI
  10.1016/j.bbrc.2021.08.001
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04713, KAKENHI-PUBLICLY-20H04879, KAKENHI-PROJECT-21H00920, KAKENHI-PROJECT-20K21536, KAKENHI-PUBLICLY-21H05504, KAKENHI-PROJECT-23K21749, KAKENHI-PROJECT-23K21750
[Journal Article] Impacts of chromatin dynamics and compartmentalization on DNA repair2021
- Author(s)
  Yasuhara Takaaki、Zou Lee
- Journal Title
  
  DNA Repair
  
  Volume: 105 Pages: 103162-103162
- DOI
  10.1016/j.dnarep.2021.103162
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20KK0339, KAKENHI-PROJECT-23K21750
[Journal Article] High linear energy transfer carbon-ion irradiation upregulates PD-L1 expression more significantly than X-rays in human osteosarcoma U2OS cells2021
- Author(s)
  Permata Tiara Bunga Mayang、Sato Hiro、Gu Wenchao、Kakoti Sangeeta、Uchihara Yuki、Yoshimatsu Yukihiko、Sato Itaru、Kato Reona、Yamauchi Motohiro、Suzuki Keiji、Oike Takahiro、Tsushima Yoshito、Gondhowiardjo Soehartati、Ohno Tatsuya、Yasuhara Takaaki、Shibata Atsushi
- Journal Title
  
  Journal of Radiation Research
  
  Volume: 62 Issue: 5 Pages: 773-781
- DOI
  10.1093/jrr/rrab050
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08195, KAKENHI-PROJECT-17H04713, KAKENHI-PUBLICLY-20H04879, KAKENHI-PROJECT-20K21536, KAKENHI-PROJECT-21K17888, KAKENHI-PUBLICLY-21H05504, KAKENHI-PROJECT-23K21749, KAKENHI-PROJECT-23K21750
[Journal Article] RNF8 promotes high linear energy transfer carbon-ion-induced DNA double-stranded break repair in serum-starved human cells2020
- Author(s)
  Nakajima Nakako Izumi、Yamauchi Motohiro、Kakoti Sangeeta、Cuihua Liu、Kato Reona、Permata Tiara Bunga Mayang、Iijima Moito、Yajima Hirohiko、Yasuhara Takaaki、Yamada Shigeru、Hasegawa Sumitaka、Shibata Atsushi
- Journal Title
  
  DNA Repair
  
  Volume: 91-92 Pages: 102872-102872
- DOI
  10.1016/j.dnarep.2020.102872
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21536, KAKENHI-PROJECT-17H04713, KAKENHI-PUBLICLY-20H04879, KAKENHI-PROJECT-18K11645, KAKENHI-PROJECT-18K18191
[Journal Article] DNA Repair and Signaling in Immune-Related Cancer Therapy2020
- Author(s)
  Kakoti Sangeeta、Sato Hiro、Laskar Siddhartha、Yasuhara Takaaki、Shibata Atsushi
- Journal Title
  
  Frontiers in Molecular Biosciences
  
  Volume: 7 Pages: 205-205
- DOI
  10.3389/fmolb.2020.00205
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21536, KAKENHI-PROJECT-17H04713, KAKENHI-PUBLICLY-20H04879, KAKENHI-PROJECT-19K08195
[Journal Article] Elucidation of the Mechanism Regulating Transcription Associated Dna Double Strand Break Repair and Its Pathway2019
- Author(s)
  Shibata Atsushi、Yasuhara Takaaki
- Journal Title
  
  Impact
  
  Volume: 2019 Issue: 3 Pages: 50-51
- DOI
  10.21820/23987073.2019.3.50
- Data Source
  KAKENHI-PROJECT-18K18191
[Journal Article] p53 deficiency augments nucleolar instability after ionizing irradiation.2019
- Author(s)
  Kakoti, S., Yamauchi, M., Gu, W., Kato, R., Yasuhara, T., Hagiwara, Y., Laskar, S., Oike, T., Sato, H., Held, KD., Nakano, T., and Shibata, A.
- Journal Title
  
  Oncology Reports
  
  Volume: 42 Pages: 2293-2302
- DOI
  10.3892/or.2019.7341
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K18191, KAKENHI-PROJECT-17H04713, KAKENHI-PROJECT-16H05388
[Journal Article] Base excision repair regulates PD-L1 expression in cancer cells2019
- Author(s)
  Permata, MBT, Hagiwara, Y., Sato, H., Yasuhara, T., Oike, T., Gondhowiardjo, S., Held, KD, Nakano, T., and Shibata, A.
- Journal Title
  
  Oncogene
  
  Volume: 印刷中 Issue: 23 Pages: 4452-4466
- DOI
  10.1038/s41388-019-0733-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K18191, KAKENHI-PROJECT-17K16420, KAKENHI-PROJECT-16H05388
[Journal Article] The role of R-loops in transcription-associated DNA double-strand break repair2019
- Author(s)
  Kato Reona、Miyagawa Kiyoshi、Yasuhara Takaaki
- Journal Title
  
  Molecular & Cellular Oncology
  
  Volume: 6 Issue: 1 Pages: 1542244-1542244
- DOI
  10.1080/23723556.2018.1542244
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K18191
[Journal Article] Human Rad52 Promotes XPG-Mediated R-loop Processing to Initiate Transcription-Associated Homologous Recombination Repair2018
- Author(s)
  Yasuhara Takaaki、Kato Reona、Hagiwara Yoshihiko、Shiotani Bunsyo、Yamauchi Motohiro、Nakada Shinichiro、Shibata Atsushi、Miyagawa Kiyoshi
- Journal Title
  
  Cell
  
  Volume: 175 Issue: 2 Pages: 558-570
- DOI
  10.1016/j.cell.2018.08.056
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K18191, KAKENHI-PROJECT-18KK0235, KAKENHI-PROJECT-18H03378, KAKENHI-PROJECT-16K12602, KAKENHI-PROJECT-26241014, KAKENHI-PROJECT-17H04713
[Journal Article] 細胞機能間ネットワークを標的としたがん治療戦略2016
- Author(s)
  安原崇哲、宮川清
- Journal Title
  
  放射線生物研究
  
  Volume: 51 Pages: 127-139
- NAID
  40020903961
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H06146
[Presentation] How Our Genome Is Protected From Mutagenesis2023
- Author(s)
  Takaaki Yasuhara
- Organizer
  Asian Young Scientist Fellowship Annual Conference 2023
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-23H04274
[Presentation] How Our Genome Is Protected From Mutagenesis2023
- Author(s)
  Takaaki Yasuhara
- Organizer
  Asian Young Scientist Fellowship Annual Conference 2023
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-22H05585
[Presentation] Condensates induced by nucleolar stresses mediate gene fusion2023
- Author(s)
  Takaaki Yasuhara
- Organizer
  The 19th Ataxia-Telangiectasia workshop (ATW2023Kyoto)
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-22H05585
[Presentation] Toward an understanding of how chromosome translocations occur2023
- Author(s)
  Takaaki Yasuhara
- Organizer
  Radiation Biology Center Mini-symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-22H05585
[Presentation] Toward an understanding of how chromosome translocations occur2023
- Author(s)
  Takaaki Yasuhara
- Organizer
  Radiation Biology Center Mini-symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20KK0339
[Presentation] RNAを介したゲノム安定性維持機構2023
- Author(s)
  安原　崇哲
- Organizer
  RNAフロンティアミーティング2023
- Invited
- Data Source
  KAKENHI-PROJECT-23K21750
[Presentation] Condensates induced by nucleolar stresses mediate gene fusion2023
- Author(s)
  Takaaki Yasuhara
- Organizer
  The 19th Ataxia-Telangiectasia workshop (ATW2023Kyoto)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21750
[Presentation] How Our Genome Is Protected From Mutagenesis2023
- Author(s)
  Takaaki Yasuhara
- Organizer
  Asian Young Scientist Fellowship Annual Conference 2023
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20KK0339
[Presentation] Condensates induced by nucleolar stresses mediate gene fusion2023
- Author(s)
  Takaaki Yasuhara
- Organizer
  The 19th Ataxia-Telangiectasia workshop (ATW2023Kyoto)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20KK0339
[Presentation] RNAを介したゲノム安定性維持機構2023
- Author(s)
  安原　崇哲
- Organizer
  RNAフロンティアミーティング2023
- Invited
- Data Source
  KAKENHI-PROJECT-20KK0339
[Presentation] Genome maintenance by transcription-associated DNA double-strand break repair2023
- Author(s)
  Takaaki Yasuhara
- Organizer
  2nd Fukuoka RNA commons
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20KK0339
[Presentation] Genome maintenance by transcription-associated DNA double-strand break repair2023
- Author(s)
  Takaaki Yasuhara
- Organizer
  2nd Fukuoka RNA commons
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-23H04274
[Presentation] Toward an understanding of how chromosome translocations occur2023
- Author(s)
  Takaaki Yasuhara
- Organizer
  Radiation Biology Center Mini-symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-23H04274
[Presentation] Heterochromatin-associated replication stress induced by oncogenic KRAS is tolerated by an ATR-PrimPol pathway2023
- Author(s)
  Igarashi T, Yasuhara T, Yano K, Zou L, and Shiotani, B
- Organizer
  The International Ataxia-Telangiectasia Workshop 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0235
[Presentation] Genome maintenance by transcription-associated DNA double-strand break repair2023
- Author(s)
  Takaaki Yasuhara
- Organizer
  2nd Fukuoka RNA commons
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21750
[Presentation] How Our Genome Is Protected From Mutagenesis2023
- Author(s)
  Takaaki Yasuhara
- Organizer
  Asian Young Scientist Fellowship Annual Conference 2023
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21750
[Presentation] RNAを介したゲノム安定性維持機構2023
- Author(s)
  安原　崇哲
- Organizer
  RNAフロンティアミーティング2023
- Invited
- Data Source
  KAKENHI-PUBLICLY-22H05585
[Presentation] RNAを介したゲノム安定性維持機構2023
- Author(s)
  安原　崇哲
- Organizer
  RNAフロンティアミーティング2023
- Invited
- Data Source
  KAKENHI-PUBLICLY-23H04274
[Presentation] Genome maintenance by transcription-associated DNA double-strand break repair2023
- Author(s)
  Takaaki Yasuhara
- Organizer
  2nd Fukuoka RNA commons
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-22H05585
[Presentation] Toward an understanding of how chromosome translocations occur2023
- Author(s)
  Takaaki Yasuhara
- Organizer
  Radiation Biology Center Mini-symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21750
[Presentation] Genome maintenance by RNA-mediated stress responses2022
- Author(s)
  Takaaki Yasuhara
- Organizer
  The 12th International Symposium Gunma University Initiative for Advanced Research
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20KK0339
[Presentation] リボソームRNAを足場とした液―液相分離によるゲノム制御機構2022
- Author(s)
  安原　崇哲
- Organizer
  第45回日本分子生物学会
- Data Source
  KAKENHI-PUBLICLY-22H05585
[Presentation] リボソームRNAを足場とした液―液相分離によるゲノム制御機構2022
- Author(s)
  安原　崇哲
- Organizer
  第45回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-23K21750
[Presentation] 染色体転座の発生メカニズムに迫る2022
- Author(s)
  安原　崇哲
- Organizer
  日本放射線影響学会第65回大会
- Data Source
  KAKENHI-PROJECT-20KK0339
[Presentation] 染色体転座の発生メカニズムに迫る2022
- Author(s)
  安原　崇哲
- Organizer
  日本放射線影響学会第65回大会
- Data Source
  KAKENHI-PROJECT-23K21750
[Presentation] 染色体転座の発生メカニズムに迫る2022
- Author(s)
  安原　崇哲
- Organizer
  日本放射線影響学会第65回大会
- Data Source
  KAKENHI-PUBLICLY-22H05585
[Presentation] リボソームRNAを足場とした液―液相分離によるゲノム制御機構2022
- Author(s)
  安原　崇哲
- Organizer
  第45回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-20KK0339
[Presentation] Genome maintenance by RNA-mediated stress responses2022
- Author(s)
  Takaaki Yasuhara
- Organizer
  The 12th International Symposium Gunma University Initiative for Advanced Research
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21750
[Presentation] RNAを介したゲノム安定性維持機構2021
- Author(s)
  安原　崇哲
- Organizer
  第２６回DNA複製・組換え・修復ワークショップ
- Data Source
  KAKENHI-PROJECT-20KK0339
[Presentation] 核内凝集体を介したがんゲノム不安定性誘導機構2021
- Author(s)
  安原　崇哲
- Organizer
  第44回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-23K21750
[Presentation] RNAを介したゲノム安定性維持機構2021
- Author(s)
  安原　崇哲
- Organizer
  第２６回DNA複製・組換え・修復ワークショップ
- Data Source
  KAKENHI-PROJECT-23K21750
[Presentation] 核内凝集体を介したがんゲノム不安定性誘導機構2021
- Author(s)
  安原　崇哲
- Organizer
  第44回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-20KK0339
[Presentation] RNA転写とDNA二重鎖切断修復のクロストーク2019
- Author(s)
  安原崇哲
- Organizer
  第42回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18K18191
[Presentation] Rad52 promotes XPG-mediated R-loop processing to initiate transcription-associated homologous recombination repair2019
- Author(s)
  Takaaki Yasuhara、Kato Reona、Shibata Atsushi、Miyagawa Kiyoshi
- Organizer
  Keystone Symposia - Genomic Instability and DNA Repair
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K18191
[Presentation] Rad52 promotes XPG-mediated R-loop processing to initiate transcription-associated homologous recombination repair2018
- Author(s)
  Takaaki Yasuhara、Kato Reona、Shibata Atsushi、Miyagawa Kiyoshi
- Organizer
  Abcam meeting - Mechanisms of Recombination 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K18191
[Presentation] Rad54Bを介した細胞機能ネットワークの解析によるがん発生機構の解明2016
- Author(s)
  安原　崇哲
- Organizer
  平成28年東京RBC新春放談会
- Place of Presentation
  東京大学（東京都文京区）
- Year and Date
  2016-02-13
- Invited
- Data Source
  KAKENHI-PROJECT-15H06146
[Presentation] 細胞機能間ネットワークを標的とした新たながん治療戦略2016
- Author(s)
  安原崇哲
- Organizer
  群大Genome Damage Discussion Group 公開セミナー
- Place of Presentation
  群馬大学
- Year and Date
  2016-05-31
- Invited
- Data Source
  KAKENHI-PROJECT-15H06146
[Presentation] The Rad54B-p53 axis limits the strength of DNA damage checkpoint2016
- Author(s)
  Takaaki Yasuhara
- Organizer
  日本放射線影響学会第59回大会
- Place of Presentation
  広島市
- Year and Date
  2016-10-26
- Data Source
  KAKENHI-PROJECT-15H06146
[Presentation] The Rad54B-p53 axis limits the strength of DNA damage checkpoint2016
- Author(s)
  Takaaki Yasuhara
- Organizer
  第 75 回日本癌学会学術総会
- Place of Presentation
  横浜市
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-15H06146
[Presentation] The novel mechanism linking cell cycle regulation to cancer development2015
- Author(s)
  安原　崇哲
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸ポートピアホテル（兵庫県神戸市）
- Year and Date
  2015-12-02
- Data Source
  KAKENHI-PROJECT-15H06146
[Presentation] がん発生の基盤となる分子メカニズムを探るー DNA損傷下における細胞周期の新たな制御因子ー2015
- Author(s)
  安原　崇哲
- Organizer
  第10回原子炉研コロキウム
- Place of Presentation
  東京工業大学原子炉工学研究所（東京都目黒区）
- Year and Date
  2015-12-18
- Invited
- Data Source
  KAKENHI-PROJECT-15H06146

1. Shibata Atsushi (30707633)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
2. 山内基弘 (60437910)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. Shiotani Bunsyo (10627665)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 中田慎一郎 (70548528)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 宮成悠介 (60469608)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 佐藤浩央

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 内原脩貴

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yasuhara Takaaki 安原 崇哲

YASUHARA Takaaki 安原 崇哲

Research Projects

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Co-Researchers

Genomic instability caused by the phase transition-induced abnormality in transcription-repair couplingPrincipal Investigator

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Genome instability induced by spatial positions in the nucleusPrincipal Investigator

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A strategy to transform genomic organization and change the gene expression pattern via controlling nucleolar condensatesPrincipal Investigator

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全ゲノム領域に共通した正確なDNA修復を保証するDSB修復経路選択機構の研究

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Investigation of the new factors regulating transcription- associated DNA double-strand break repairPrincipal Investigator

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Elucidation of transcription-coupled chromosomal translocation pathways between gene loci

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The mechanism for gene fusion mediated by condensatesPrincipal Investigator

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The roles of R-loop structure in DNA damage signaling and genomePrincipal Investigator

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Elucidation of the mechanism underlying DNA replication stress response regulating genomic instability

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Mechanism for cancer-related upregulation of the Rad54B-mediated cellular function networkPrincipal Investigator

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[Journal Article] An ATR-PrimPol pathway confers tolerance to oncogenic KRAS-induced and heterochromatin-associated replication stress2023

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[Journal Article] Condensates induced by transcription inhibition localize active chromatin to nucleoli2022

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[Journal Article] ゲノム安定性維持機構におけるarcRNA の役割2022

Author(s)

Journal Title

Data Source

[Journal Article] ゲノム安定性維持機構におけるarcRNA の役割2022

Yasuhara Takaaki 安原崇哲

YASUHARA Takaaki 安原崇哲