Okubo Torahiko 大久保寅彦

Researcher Number	90762196
Other IDs
Affiliation (Current)	2025: 北海道大学, 保健科学研究院, 講師
Affiliation (based on the past Project Information) *help	2017 – 2025: 北海道大学, 保健科学研究院, 講師 2015 – 2017: 北海道大学, 保健科学研究院, 助教
Review Section/Research Field	Principal Investigator Basic Section 49050:Bacteriology-related / Basic Section 58020:Hygiene and public health-related: including laboratory approach / Parasitology (including sanitary zoology) / Laboratory medicine Except Principal Investigator Basic Section 58050:Fundamental of nursing-related / Basic Section 49050:Bacteriology-related / Basic Section 64010:Environmental load and risk assessment-related / Medium-sized Section 58:Society medicine, nursing, and related fields / Bacteriology (including mycology) / Laboratory medicine / Animal production science
Keywords	Principal Investigator 微生物間相互作用 / 繊毛虫 / 原生生物 / 薬剤耐性菌 / レジオネラ / 下水 / ワンヘルス / 微生物 / クオラムセンシング / 原生動物 / 食品衛生 / 細菌叢 … More Except Principal Investigator … More 高頻度接触面 / 感染 / 日常生活動作 / 看護 / 細菌学 / 低酸素 / クラミジア / 薬剤耐性菌 / ドラッグスクリーニング / 情報伝達経路 / MAPK / 芳香族炭化水素受容体AhR / ドラッグ・スクリーニング / PI3K/AKTシグナル / 癌創薬 / ミトコンドリア / 癌細胞 / クラミジア・トラコマティス / 分子疫学 / 細菌 / ST131 / フルオロキノロン耐性 / 大腸菌 / 薬剤耐性 / メタゲノム解析 / nhaA / エアサンプラー / 乾燥抵抗性 / 環境細菌 / 公共環境 / 温度制御 / 院内感染 / 病原細菌 / 人肌加温 / Adenosine triphosphate / 生菌数 / 入院患者 / 患者周辺環境 / 接触感染 / 原始クラミジア / 環境クラミジア / Na+/H+アンチポーター / 共生 / 細菌運搬現象 / ネオクラミジア / 運搬現象 / レジオネラ / 原始的なクラミジア / 共生細菌 / アメーバ / 膣検体 / 臨床細菌 / メタボローム解析 / 生殖器 / 菌叢 / 腸内細菌科細菌 / 膣スワブ / メタボローム / 不妊 / ルシフェラーゼ / IFNγ / 腟粘膜面菌叢 / Chlamydia trachomatis / 低酸素環境 / アポトーシス / インドール / 菌叢解析 / 腟粘膜面 / 性感染症 / プロバイオティクス / 野生動物 / 家畜 / プロバイオティクス乳酸菌 / ウガンダ / アフリカ Less

パンデミッククローンST131をモデルとした大腸菌臨床株の乾燥抵抗性メカニズムの解明Principal Investigator
- Principal Investigator
  
  大久保寅彦
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  Hokkaido University
日常生活動作レベルが高頻度接触面の細菌動態に与える影響と感染リスク判断への応用
- Principal Investigator
  
  宇野智子
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58050:Fundamental of nursing-related
- Research Institution
  Sapporo Medical University
Functional elucidation of novel effectors of Legionella pneumophila approached through interactions with unique ciliatePrincipal Investigator
- Principal Investigator
  
  大久保寅彦
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  Hokkaido University
Elucidation of colonization mechanism of an international high-risk pathogenic bacteria in the community
- Principal Investigator
  
  Sato Toyotaka
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 64010:Environmental load and risk assessment-related
- Research Institution
  Hokkaido University
New development of research to elucidate the intracellular adaptation mechanism of genital chlamydia unraveled from its similarity to cancer cells
- Principal Investigator
  
  山口博之
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  Hokkaido University
入院患者の日常生活動作レベルがベッド周辺環境の微生物汚染に及ぼす影響
- Principal Investigator
  
  宇野智子
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58050:Fundamental of nursing-related
- Research Institution
  Sapporo Medical University
Understanding and application of microbiota in building environment: creation of pathogen control theory by temperature control
- Principal Investigator
  
  Yamaguchi Hiroyuki
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 58:Society medicine, nursing, and related fields
- Research Institution
  Hokkaido University
Dissemination of antimicrobial-resistant bacteria from hospital sewage to natural environmentsPrincipal Investigator
- Principal Investigator
  
  Okubo Torahiko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  Hokkaido University
The collaborative research project for drug resistance bacteria in animal agriculture of tropical Africa and finding the alternatives for drug use.
- Principal Investigator
  
  USHIDA Kazunari
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Animal production science
- Research Institution
  Chubu University
  Kyoto Prefectural University
Exploring critical factors responsible for regulating the survival of Chlamydia trachomatis into cervical mucosa
- Principal Investigator
  
  Yamaguchi Hiroyuki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Hokkaido University
The role of amoebal endosymbiont in predator-prey interactions
- Principal Investigator
  
  Yamaguchi Hiroyuki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Bacteriology (including mycology)
- Research Institution
  Hokkaido University
Effect of bacterial signal molecule AI-2 on the metabolism and pathogenicity of protozoaPrincipal Investigator
- Principal Investigator
  
  Okubo Torahiko
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Parasitology (including sanitary zoology)
- Research Institution
  Hokkaido University
市販鶏肉の表面で繰り広げられる細菌と原生動物の相互作用の可視化と応用Principal Investigator
- Principal Investigator
  
  大久保寅彦
- Project Period (FY)
  2015
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Laboratory medicine
- Research Institution
  Hokkaido University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] Differential impact of environmental factors on airborne live bacteria and inorganic particles in an underground walkway2024
- Author(s)
  Yamaguchi Hiroyuki、Okubo Torahiko、Nozaki Eriko、Osaki Takako
- Journal Title
  
  PLOS ONE
  
  Volume: 19 Issue: 3 Pages: e0300920-e0300920
- DOI
  10.1371/journal.pone.0300920
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K20613
[Journal Article] Human pathogenic bacteria on high-touch dry surfaces can be controlled by warming to human-skin temperature under moderate humidity2023
- Author(s)
  Konno Ayano、Okubo Torahiko、Enoeda Yoshiaki、Uno Tomoko、Sato Toyotaka、Yokota Shin-ichi、Yano Rika、Yamaguchi Hiroyuki
- Journal Title
  
  PLOS ONE
  
  Volume: 18 Issue: 9 Pages: 0291765-0291765
- DOI
  10.1371/journal.pone.0291765
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19416, KAKENHI-PROJECT-20K20613, KAKENHI-PROJECT-21H03622
[Journal Article] Chlamydia trachomatis relies on the scavenger role of aryl hydrocarbon receptor with detyrosinated tubulin for its intracellular growth, but this is impaired by excess indole2023
- Author(s)
  Zhang Saicheng、Funahashi Yuki、Tanaka Satoho、Okubo Torahiko、Thapa Jeewan、Nakamura Shinji、Higashi Hideaki、Yamaguchi Hiroyuki
- Journal Title
  
  Microbes and Infection
  
  Volume: 25 Issue: 5 Pages: 105097-105097
- DOI
  10.1016/j.micinf.2022.105097
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K21378
[Journal Article] Chlamydia trachomatis Requires Functional Host-Cell Mitochondria and NADPH Oxidase 4/p38MAPK Signaling for Growth in Normoxia2022
- Author(s)
  Thapa Jeewan、Yoshiiri Gen、Ito Koki、Okubo Torahiko、Nakamura Shinji、Furuta Yoshikazu、Higashi Hideaki、Yamaguchi Hiroyuki
- Journal Title
  
  Frontiers in Cellular and Infection Microbiology
  
  Volume: 12
- DOI
  10.3389/fcimb.2022.902492
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K21378
[Journal Article] Chlamydia trachomatis L2/434/Bu Favors Hypoxia for its Growth in Human Lymphoid Jurkat Cells While Maintaining Production of Proinflammatory Cytokines2022
- Author(s)
  Tsujikawa Ryoya、Thapa Jeewan、Okubo Torahiko、Nakamura Shinji、Zhang Saicheng、Furuta Yoshikazu、Higashi Hideaki、Yamaguchi Hiroyuki
- Journal Title
  
  Current Microbiology
  
  Volume: 79 Issue: 9
- DOI
  10.1007/s00284-022-02961-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K21378
[Journal Article] Usefulness of a 3D-printing air sampler for capturing live airborne bacteria and exploring the environmental factors that can influence bacterial dynamics2021
- Author(s)
  Mori Saaya、Ishiguro Sakura、Miyazaki Satoru、Okubo Torahiko、Omori Ryosuke、Kai Ayako、Sugiyama Kyohei、Kawashiro Airi、Sumi Masato、Thapa Jeewan、Nakamura Shinji、Katoh Chietsugu、Yamaguchi Hiroyuki
- Journal Title
  
  Research in Microbiology
  
  Volume: 172 Issue: 6 Pages: 103864-103864
- DOI
  10.1016/j.resmic.2021.103864
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K20613
[Journal Article] Distribution of amoebal endosymbiotic environmental chlamydia Neochlamydia S13 via amoebal cytokinesis2021
- Author(s)
  Okude Miho、Matsuo Junji、Yamazaki Tomohiro、Saito Kentaro、Furuta Yoshikazu、Nakamura Shinji、Thapa Jeewan、Okubo Torahiko、Higashi Hideaki、Yamaguchi Hiroyuki
- Journal Title
  
  Microbiology and Immunology
  
  Volume: 65 Issue: 3 Pages: 115-124
- DOI
  10.1111/1348-0421.12871
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K20613, KAKENHI-PROJECT-18K19436, KAKENHI-PROJECT-23K21378
[Journal Article] Wild ciliates differ in susceptibility to Legionella pneumophila JR322021
- Author(s)
  Kawashiro Airi、Okubo Torahiko、Nakamura Shinji、Thapa Jeewan、Miyake Masaki、Yamaguchi Hiroyuki
- Journal Title
  
  Microbiology
  
  Volume: 167 Issue: 8 Pages: 1-15
- DOI
  10.1099/mic.0.001078
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K19403, KAKENHI-PROJECT-20K20613
[Journal Article] Hypoxia promotes Chlamydia trachomatis L2/434/Bu growth in immortal human epithelial cells via activation of the PI3K-AKT pathway and maintenance of a balanced NAD+/NADH ratio2020
- Author(s)
  Thapa Jeewan、Hashimoto Kent、Sugawara Saori、Tsujikawa Ryoya、Okubo Torahiko、Nakamura Shinji、Yamaguchi Hiroyuki
- Journal Title
  
  Microbes and Infection
  
  Volume: 22 Issue: 9 Pages: 441-450
- DOI
  10.1016/j.micinf.2020.04.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K20613
[Journal Article] Isolation and characterization of antimicrobial-resistant Escherichia coli from retail meats from roadside butcheries in Uganda2020
- Author(s)
  Okubo T, Yossapol M, Ikushima S, Kakooza S, Wampande EM, Asai T, Tsuchida S, Ohya K, Maruyama F, Kabasa JD, Ushida K.
- Journal Title
  
  Foodborne Pathogens and Disease
  
  Volume: 17
- NAID
  120007168585
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02767
[Journal Article] Chlamydia pneumoniae enhances Interleukin 8 (IL-8) production with reduced azithromycin sensitivity under hypoxia2019
- Author(s)
  Matsuo Junji、Sakai Kohei、Okubo Torahiko、Yamaguchi Hiroyuki
- Journal Title
  
  APMIS
  
  Volume: 127 Issue: 3 Pages: 131-138
- DOI
  10.1111/apm.12924
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05225, KAKENHI-PROJECT-16K15270
[Journal Article] A simple and short microbiology practical improves undergraduate nursing students’ awareness of bacterial traits and ability to avoid spreading infections2019
- Author(s)
  Yano Rika、Okubo Torahiko、Shimoda Tomoko、Matsuo Junji、Yamaguchi Hiroyuki
- Journal Title
  
  BMC Medical Education
  
  Volume: 19 Issue: 1 Pages: 1-7
- DOI
  10.1186/s12909-019-1483-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05225, KAKENHI-PROJECT-16K15270
[Journal Article] Activation of caspase-3 during Chlamydia trachomatis-induced apoptosis at a late stage2019
- Author(s)
  Matsuo Junji、Haga Sanae、Hashimoto Kent、Okubo Torahiko、Ozawa Takeaki、Ozaki Michitaka、Yamaguchi Hiroyuki
- Journal Title
  
  Canadian Journal of Microbiology
  
  Volume: 65 Issue: 2 Pages: 135-143
- DOI
  10.1139/cjm-2018-0408
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05225, KAKENHI-PROJECT-16K15270, KAKENHI-PROJECT-26220805, KAKENHI-PROJECT-17H04022, KAKENHI-PROJECT-15H05659, KAKENHI-PROJECT-19H00900, KAKENHI-PROJECT-20K20472
[Journal Article] Screening of hospital-manhole sewage using MacConkey agar with cefotaxime reveals extended-spectrum β-lactamase (ESBL)-producing Escherichia coli2019
- Author(s)
  Okubo Torahiko、Hasegawa Takaki、Fukuda Akira、Thapa Jeewan、Usui Masaru、Tamura Yutaka、Yamaguchi Hiroyuki
- Journal Title
  
  International Journal of Antimicrobial Agents
  
  Volume: 54 Issue: 6 Pages: 831-833
- DOI
  10.1016/j.ijantimicag.2019.08.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K19403
[Journal Article] Impact of bacterial traces belonging to the Enterobacteriaceae on the prevalence of Chlamydia trachomatis in women visiting a community hospital in Japan2018
- Author(s)
  Taki Keisuke、Watanabe Takanori、Matsuo Junji、Sakai Kouhei、Okubo Torahiko、Matsushita Mizue、Abe Kiyotaka、Minami Kunihiro、Yamaguchi Hiroyuki
- Journal Title
  
  Journal of Infection and Chemotherapy
  
  Volume: 24 Issue: 10 Pages: 815-821
- DOI
  10.1016/j.jiac.2018.06.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05225, KAKENHI-PROJECT-16K15270
[Journal Article] Impact of capsaicin, an active component of chili pepper, on pathogenic chlamydial growth ( Chlamydia trachomatis and Chlamydia pneumoniae ) in immortal human epithelial HeLa cells2018
- Author(s)
  Yamakawa Kazuya、Matsuo Junji、Okubo Torahiko、Nakamura Shinji、Yamaguchi Hiroyuki
- Journal Title
  
  J Infect Chemother
  
  Volume: 24 Issue: 2 Pages: 130-137
- DOI
  10.1016/j.jiac.2017.10.007
- NAID
  120006558989
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15270, KAKENHI-PROJECT-16H05225
[Journal Article] Analysis of adult damselfly fecal material aids in the estimation of antibiotic-resistant Enterobacterales contamination of the local environment2018
- Author(s)
  Yamaguchi Yuyu、Okubo Torahiko、Matsushita Mizue、Wataji Masashi、Iwasaki Sumio、Hayasaka Kasumi、Akizawa Kouzi、Matsuo Junji、Shimizu Chikara、Yamaguchi Hiroyuki
- Journal Title
  
  PeerJ
  
  Volume: 6 Pages: e5755-e5755
- DOI
  10.7717/peerj.5755
- NAID
  120006540071
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05225, KAKENHI-PROJECT-16K15270
[Journal Article] Phenotypic and genotypic analyses of antimicrobial- resistant bacteria in livestock in Uganda.2018
- Author(s)
  Okubo, T., Yossapol, M., Maruyama, F., Wampande, E. M., Kakooza, S., Ohya, K., Tsuchida, S., Asai, T., Kabasa, J. D. and Ushida, K.
- Journal Title
  
  Transboundary Emerg. Dis.
  
  Volume: 66 Issue: 1 Pages: 317-326
- DOI
  10.1111/tbed.13024
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H01782, KAKENHI-PROJECT-16H02767, KAKENHI-PROJECT-26304039
[Journal Article] Acanthamoeba S13WT relies on its bacterial endosymbiont to backpack human pathogenic bacteria and resist Legionella infection on solid media.2018
- Author(s)
  Okubo T, Matsushita M, Nakamura S, Matsuo J, Nagai H, Yamaguchi H.
- Journal Title
  
  Environ Microbiol Rep
  
  Volume: - Issue: 3 Pages: 344-354
- DOI
  10.1111/1758-2229.12645
- NAID
  120006649176
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15270, KAKENHI-PROJECT-16H05225, KAKENHI-PROJECT-16K19113
[Journal Article] Lateral Gene Transfer Between Protozoa-Related Giant Viruses of Family Mimiviridae and Chlamydiae2018
- Author(s)
  Watanabe Takanori、Yamazaki Sumire、Maita Chinatsu、Matushita Mizue、Matsuo Junji、Okubo Torahiko、Yamaguchi Hiroyuki
- Journal Title
  
  Evolutionary Bioinformatics
  
  Volume: 14 Pages: 1-19
- DOI
  10.1177/1176934318788337
- NAID
  120006491545
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05225, KAKENHI-PROJECT-16K15270
[Journal Article] Amoebal endosymbiont Neochlamydia protects host amoebae against Legionella pneumophila infection by preventing Legionella entry2018
- Author(s)
  Maita Chinatsu、Matsushita Mizue、Miyoshi Masahiro、Okubo Torahiko、Nakamura Shinji、Matsuo Junji、Takemura Masaharu、Miyake Masaki、Nagai Hiroki、Yamaguchi Hiroyuki
- Journal Title
  
  Microbes Infect
  
  Volume: - Issue: 4 Pages: 236-244
- DOI
  10.1016/j.micinf.2017.12.012
- NAID
  120006626558
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15270, KAKENHI-PROJECT-16H05225
[Journal Article] Long-term survival of Naegleria polaris from Antarctica after 10 years of storage at 4°C2018
- Author(s)
  Matsuo Junji、Nakamura Shinji、Okubo Torahiko、Fukui Manabu、Yamaguchi Hiroyuki
- Journal Title
  
  Parasitol Res
  
  Volume: 117 Issue: 3 Pages: 937-941
- DOI
  10.1007/s00436-018-5779-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15270, KAKENHI-PROJECT-16H05225
[Journal Article] Subtle changes in host cell density cause a serious error in monitoring of the intracellular growth of Chlamydia trachomatis in a low-oxygen environment: Proposal for a standardized culture method2018
- Author(s)
  Sakai Kouhei、Matsuo Junji、Watanabe Takanori、Okubo Torahiko、Nakamura Shinji、Yamaguchi Hiroyuki
- Journal Title
  
  Journal of Microbiological Methods
  
  Volume: 153 Pages: 84-91
- DOI
  10.1016/j.mimet.2018.09.007
- NAID
  120006734162
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05225, KAKENHI-PROJECT-16K15270
[Journal Article] Tetrahymena promotes interactive transfer of carbapenemase gene encoded in plasmid between fecal Escherichia coli and environmental Aeromonas caviae2018
- Author(s)
  Matsushita Mizue、Okubo Torahiko、Hasegawa Takaki、Matsuo Junji、Watanabe Takanori、Iwasaki Sumio、Fukumoto Tatsuya、Hayasaka Kasumi、Akizawa Kozi、Shimizu Chikara、Yamaguchi Hiroyuki
- Journal Title
  
  Microbiology and Immunology
  
  Volume: 62 Issue: 11 Pages: 720-728
- DOI
  10.1111/1348-0421.12656
- NAID
  120006769953
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05225, KAKENHI-PROJECT-16K15270
[Journal Article] 13. Ciliates promote the transfer of a plasmid encoding blaNDM-5 from Escherichia coli, isolated from a hospital in Japan, to other human pathogens.2017
- Author(s)
  Okubo T, Matushita M, Ohara Y, Matsuo J, Oguri S, Fukumoto T, Hayasaka K, Akizawa K, Shibuya H, Shimizu C, Yamaguchi H.
- Journal Title
  
  Int J Antimicrob Agents
  
  Volume: 49 Issue: 3 Pages: 387-388
- DOI
  10.1016/j.ijantimicag.2017.01.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05225, KAKENHI-PROJECT-16K15270, KAKENHI-PROJECT-16K19113
[Journal Article] Diversity changes of microbial communities into hospital surface environments2017
- Author(s)
  Yano Rika、Shimoda Tomoko、Watanabe Reina、Kuroki Yasutoshi、Okubo Torahiko、Nakamura Shinji、Matsuo Junji、Yoshimura Sadako、Yamaguchi Hiroyuki
- Journal Title
  
  J Infect Chemother
  
  Volume: 23 Issue: 7 Pages: 439-445
- DOI
  10.1016/j.jiac.2017.03.016
- NAID
  120006491481
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15270, KAKENHI-PROJECT-16H05225
[Journal Article] Walker occupancy has an impact on changing airborne bacterial communities in an underground pedestrian space, as small-dust particles increased with raising both temperature and humidity2017
- Author(s)
  Okubo Torahiko、Osaki Takako、Nozaki Eriko、Uemura Akira、Sakai Kouhei、Matushita Mizue、Matsuo Junji、Nakamura Shinji、Kamiya Shigeru、Yamaguchi Hiroyuki
- Journal Title
  
  PLOS ONE
  
  Volume: 12 Issue: 9 Pages: e0184980-e0184980
- DOI
  10.1371/journal.pone.0184980
- NAID
  120006347218
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08471, KAKENHI-PROJECT-16K15270, KAKENHI-PROJECT-16H05225
[Journal Article] Draft Genome Sequences of Legionella pneumophila JR32 and Lp01 Laboratory Strains Domesticated in Japan2016
- Author(s)
  Maita C, Matushita M, Okubo T, Matsuo J, Miyake M, Nagai H, Yamaguchi H
- Journal Title
  
  Genome Announc
  
  Volume: 4 Issue: 4
- DOI
  10.1128/genomea.00791-16
- NAID
  120005955459
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05225, KAKENHI-PROJECT-16K15270
[Journal Article] Acanthamoeba containing endosymbiotic chlamydia isolated from hospital environments and its potential role in inflammatory exacerbation2016
- Author(s)
  Fukumoto T, Matsuo J, Okubo T, Nakamura S, Miyamoto K, Oka K, Takahashi M, Akizawa K, Shibuya H, Shimizu C, Yamaguchi H
- Journal Title
  
  BMC Microbiol
  
  Volume: 16 Pages: 292-292
- NAID
  120005905631
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05225
[Journal Article] Acanthamoeba containing endosymbiotic chlamydia isolated from hospital environments and its potential role in inflammatory exacerbation.2016
- Author(s)
  Fukumoto T, Matsuo J, Okubo T, Nakamura S, Miyamoto K, Oka K, Takahashi M, Akizawa K, Shibuya H, Shimizu C, Yamaguchi H.
- Journal Title
  
  BMC Microbiol.
  
  Volume: 16 Pages: 292-292
- NAID
  120005905631
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K15270
[Presentation] 偏性細胞内寄生性のChlamydia trachomatis (L2 434/Bu)は低酸素で培養した宿主細胞環境を好む2023
- Author(s)
  李睿語、張賽成、大久保寅彦、山口博之
- Organizer
  第96回日本細菌学会総会(姫路)
- Data Source
  KAKENHI-PROJECT-23K21378
[Presentation] 繊毛虫の殺滅現象を利用したLegionella pneumophila の新規病原因子の探索2023
- Author(s)
  大久保寅彦、山口博之
- Organizer
  第96回日本細菌学会総会学術集会
- Data Source
  KAKENHI-PROJECT-22K07051
[Presentation] 雪中生細菌数は流動人口密度と関連しその密度が低値を示す場所では菌叢の多様性が高まる傾向が見られた2023
- Author(s)
  栗城琴華、森沙彩、大久保寅彦、北条　史、大崎敬子、山口博之
- Organizer
  第88回日本細菌学会北海道支部学術総会. 帯広. 2023
- Data Source
  KAKENHI-PROJECT-20K20613
[Presentation] 病原性クラミジアL2はその細胞内増殖に芳香族炭化水素受容体と脱チロンシン化チューブリンを要求する2023
- Author(s)
  張賽成、大久保寅彦、中村眞二、東秀明、山口博之
- Organizer
  第96回日本細菌学会総会(姫路)
- Data Source
  KAKENHI-PROJECT-23K21378
[Presentation] 環境クラミジアが共生するアメーバは寒天培地上で何故大腸菌を捕食せずに生きたまま運搬するのか: アメーバによる運搬と菌体サイズとの関連性2023
- Author(s)
  大久保寅彦、竹田流碧、筒井悠可、山口博之
- Organizer
  第88回日本細菌学会北海道支部学術総会. 札幌. 2023
- Data Source
  KAKENHI-PROJECT-20K20613
[Presentation] Exploration for novel signal transduction pathways utilized by Chlamydia trachomatis L2 through screening approved drug libraries2023
- Author(s)
  Hiroyuki Yamaguchi, Ruiyu Li, Saicheng Zhang, Torahiko Okubo
- Organizer
  アメリカ微生物学会 ASM microbe 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21378
[Presentation] 低酸素環境における感染細胞内での病原性クラミジア(L2 434/Bu)の増殖はメチオニン代謝産物量の変化に依存する2023
- Author(s)
  李睿語、張賽成、タパ・ジーワン、大久保寅彦、東秀明、山口博之
- Organizer
  第88回日本細菌学会北海道支部学術総会(帯広)
- Data Source
  KAKENHI-PROJECT-23K21378
[Presentation] Snow-living bacteria are associated with human density, and the low density increases the diversity of the bacterial flora2023
- Author(s)
  Kuriki K, Mori S, Okubo T, Hojo F, Osaki T, Yamaguchi H
- Organizer
  The 6th FHS International Conference, 札幌, 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20613
[Presentation] 療関連感染の制御に向けた検証：人肌に温めた手すりデバイス上での大腸菌の生存性2023
- Author(s)
  今野綾乃、大久保寅彦、山口博之
- Organizer
  第96回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-20K20613
[Presentation] 承認薬ライブラリーのスクリーニングによるChlamydia trachomatis (L2 434/Bu株) が感染細胞内で利用する新たな標的分子の探索2023
- Author(s)
  張　賽成、李　睿語、大久保寅彦、山口博之
- Organizer
  第88回日本細菌学会北海道支部学術総会(帯広)
- Data Source
  KAKENHI-PROJECT-23K21378
[Presentation] Soil bacteria release and migrate into the air in response to change in environmental factors: an experimental field study2023
- Author(s)
  OKUBO T, YAMAGUCHI H
- Organizer
  アメリカ微生物学会 ASM microbe 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20613
[Presentation] Chlamydia trachomatisL2 (434/Bu株)が感染細胞内で利用するMAPKおよびPI3K-AKT経路に付随する新たな標的分子の探索2023
- Author(s)
  黒岩青空, 髙橋小夏, 中村穂香, 大久保寅彦, 山口博之
- Organizer
  第88回日本細菌学会北海道支部学術総会(帯広)
- Data Source
  KAKENHI-PROJECT-23K21378
[Presentation] 主成分解析と一般化線型モデルによる札幌地下歩行空間に浮かぶ集落形成菌数に影響を及ぼす環境因子の可視化2023
- Author(s)
  山口博之、森沙彩、今野綾乃、大崎敬子、大久保寅彦
- Organizer
  第96回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-20K20613
[Presentation] 環境因子の変動に伴う土壌細菌の空気中への浮遊: 生菌回収用自作エアサンプラーによる野外調査の試み2023
- Author(s)
  森沙彩、大久保寅彦、山口博之
- Organizer
  第96回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-20K20613
[Presentation] Chlamydia trachomatis感染時における細胞増殖を促す受容体のアダプター分子 GAB2の影響2023
- Author(s)
  黒岩青空, 高橋小夏, 中村穂香, 大久保寅彦, 山口博之
- Organizer
  第88回日本細菌学会北海道支部学術総会(帯広)
- Data Source
  KAKENHI-PROJECT-23K21378
[Presentation] Legionella pneumophila JR32による野外由来繊毛虫Anteglaucoma CS11Aの殺滅機構に関する検2022
- Author(s)
  川代愛梨，大久保寅彦，中村眞二，Thapa Jeewan，山口博之
- Organizer
  第95回日本細菌学会総会(オンライン開催)
- Data Source
  KAKENHI-PROJECT-20K20613
[Presentation] The Molecular Mechanism by Which Legionella Pneumophila JR32 Instantly Kills Anteglaucoma Harbinensis CS11A, a Ciliate Isolated from Sewage2022
- Author(s)
  Okubo T.
- Organizer
  ASM Microbe 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07051
[Presentation] 乾燥した物質表面の温度・湿度制御はヒト病原細菌の生存抑制に有用か－高頻度接触面を介した医療関連感染を減らすために－2022
- Author(s)
  今野綾乃、大久保寅彦、山口博之
- Organizer
  第16回日本臨床検査学教育学会学術大会
- Data Source
  KAKENHI-PROJECT-20K20613
[Presentation] Combined effect of temperature and humidity on the survival of Escherichia coli DH5α on dry surfaces2022
- Author(s)
  Ayano Konno、Torahiko Okubo、Hiroyuki Yamaguchi
- Organizer
  ASM Microbe 2022 (アメリカ微生物学会)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20613
[Presentation] Interaction between Legionella pneumophila and ciliate Anteglaucoma , which is killed by co-culturing2022
- Author(s)
  Okubo T, Kawashiro A, Gengyo R, Tanishi R, Yamaguchi H.
- Organizer
  The 10th International Conference on Legionella
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07051
[Presentation] インドールは芳香族炭化水素受容体からの刺激を阻害することで病原性クラミジアL2の細胞内増殖を抑制する2022
- Author(s)
  山口博之、タパ・ジーワン、大久保寅彦、中村眞二、古田芳一、東秀明
- Organizer
  第95回日本細菌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K21378
[Presentation] 既存薬ライブラリーのスクリーニングから探る病原性クラミジアが感染細胞内で利用する新たなシグナル伝達系について2022
- Author(s)
  李睿語、張賽成、タパジーワン、大久保寅彦、山口博之
- Organizer
  第16回日本臨床検査学教育学会学術大会(埼玉)
- Data Source
  KAKENHI-PROJECT-23K21378
[Presentation] 土壌細菌は環境因子の変動に伴い本当に空気中に舞い上がり浮遊するのか: 生菌回収用自作エアサンプラーを用いた野外調査の試み2022
- Author(s)
  森沙彩、甲斐絢子、杉山恭平、鷲見優斗、大久保寅彦、山口博之
- Organizer
  第16回日本臨床検査学教育学会学術大会
- Data Source
  KAKENHI-PROJECT-20K20613
[Presentation] 既存薬ライブラリーのスクリーニングから探る病原性クラミジア(Chlamydia trachomatis L2 434/Bu)が感染細胞内で利用する新たなシグナル伝達系について2022
- Author(s)
  李睿語、張賽成、タパジーワン、大久保寅彦、山口博之
- Organizer
  第87回日本細菌学会北海道支部学術総会(札幌)
- Data Source
  KAKENHI-PROJECT-23K21378
[Presentation] 土壌細菌は環境因子の変動に伴い本当に空気中に舞い上がり浮遊するのか: 生菌回収用自作エアサンプラーを用いた野外調査の試み2022
- Author(s)
  森沙彩, 大久保寅彦, 山口博之
- Organizer
  第95回日本細菌学会総会(オンライン開催)
- Data Source
  KAKENHI-PROJECT-20K20613
[Presentation] 主成分解析による地下歩行空間に浮遊する集落形成細菌数に影響を及ぼす環境因子とその特徴の可視化2022
- Author(s)
  山口博之、森沙彩、今野綾乃、大久保寅彦
- Organizer
  第87回日本細菌学会北海道支部学術総会
- Data Source
  KAKENHI-PROJECT-20K20613
[Presentation] インドールによるChlamydia trachomatis L2(434/Bu)のヒト上皮系株化細胞(HEp-2)内での増殖抑制機構:芳香族炭化水素受容体の関連性について2022
- Author(s)
  張賽成、タパ・ジーワン、大久保寅彦、中村眞二、東秀明、山口博之
- Organizer
  第87回日本細菌学会北海道支部学術総会(札幌)
- Data Source
  KAKENHI-PROJECT-23K21378
[Presentation] 乾燥面の温度と湿度上昇はその表面に付着した病原体の生存菌数を大幅に低減させる2022
- Author(s)
  盛永和樹、今野綾乃、大久保寅彦、山口博之
- Organizer
  第87回日本細菌学会北海道支部学術総会
- Data Source
  KAKENHI-PROJECT-20K20613
[Presentation] One Health Approachに基づいたフルオロキノロン耐性大腸菌の市中内拡散・定着様式の解明2022
- Author(s)
  佐藤豊孝, 立花徹, 玉井聡, 星野祐治, 鳥越慎吾, 榊原啓一郎, 前谷茂樹, 福田昭, 大久保寅彦, 臼井優, 髙橋聡, 横田伸一, 田村豊, 堀内基広
- Organizer
  第165回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-21H03622
[Presentation] Legionella pneumophila JR32 による野外由来繊毛虫 Anteglaucoma CS11A の殺滅機構に関する検討2022
- Author(s)
  川代愛梨，大久保寅彦，中村眞二，タパジーワン，山口博之
- Organizer
  第95回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-19K19403
[Presentation] Molecular mechanism by which Legionella pneumophila JR32 instantly kills Anteglaucoma harbinensis CS11A, a ciliate isolated from sewage2022
- Author(s)
  Torahiko Okubo、Hiroyuki Yamaguchi
- Organizer
  ASM Microbe 2022 (アメリカ微生物学会)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20613
[Presentation] 医療関連感染予防のための実用化を見据えた検証: 温度制御を施した手すり型デバイス上での大腸菌の生存性について2022
- Author(s)
  今野綾乃、盛永和樹、大久保寅彦、山口博之
- Organizer
  第87回日本細菌学会北海道支部学術総会
- Data Source
  KAKENHI-PROJECT-20K20613
[Presentation] Chlamydia trachomatis L2 (434 / Bu)は、通常酸素分圧下において細胞内で増殖するためにNOX4/p38MAPK経路と健全なミトコンドリアを要求する2022
- Author(s)
  山口博之、タパジーワン、中村眞二、大久保寅彦、古田芳一、東秀明
- Organizer
  第16回細菌学若手コロッセウム(札幌)
- Data Source
  KAKENHI-PROJECT-23K21378
[Presentation] Soil bacteria float in the air according to the changes of environmental factors: a field study2022
- Author(s)
  Mori Saaya、Torahiko Okubo、Hiroyuki Yamaguchi
- Organizer
  ASM Microbe 2022 (アメリカ微生物学会)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20613
[Presentation] 既存薬ライブラリーのスクリーニングによる病原性クラミジアが利用する細胞内シグナル伝達系の探索2022
- Author(s)
  李睿語、張賽成、タパジーワン、大久保寅彦、山口博之
- Organizer
  第16回細菌学若手コロッセウム(札幌)
- Data Source
  KAKENHI-PROJECT-23K21378
[Presentation] Na+/H+アンチポーター(NhaA)は大腸菌の乾燥抵抗性を規定する2021
- Author(s)
  榎枝秀朗、田中菜那、大久保寅彦、佐藤豊孝、横田伸一、山口博之
- Organizer
  第94回日本細菌学会総会, オンライン
- Data Source
  KAKENHI-PROJECT-20K20613
[Presentation] 下水処理場からシリンジ分離法を用いて分離した繊毛虫とレジオネラの相互作用2021
- Author(s)
  川代愛梨，大久保寅彦，タパジーワン，山口博之
- Organizer
  第94回日本細菌学会総会, オンライン
- Data Source
  KAKENHI-PROJECT-20K20613
[Presentation] Chlamydia trachomatis L2 434/Bu relies on mitochondria with NOX4-dependent pathway under normoxia, but is partial in hypoxia2021
- Author(s)
  Hiroyuki Yamaguchi, Thapa Jeewan, Shinji Nakamura, Okubo Torahiko, Yoshikazu Furuta, Hideaki Higashi
- Organizer
  アメリカ微生物学会ASM World Microbe Forum (オンライン開催)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21378
[Presentation] 高頻度接触乾燥面での大腸菌の生存性を規定する因子の同定とその制御法の探索2021
- Author(s)
  今野綾乃，藤井菜央, 榎枝秀朗, 大久保寅彦, Thapa Jeewan, 佐藤豊孝，横田伸一，山口博之
- Organizer
  第86回日本細菌学会北海道支部学術総会*国内地方(オンライン開催)
- Data Source
  KAKENHI-PROJECT-20K20613
[Presentation] Acanthamoeba S13WT relies on its bacterial endosymbiont to backpack Escherichia coli on solid media in NhaA-dependent manner2021
- Author(s)
  T. Okubo, N. Tanaka, C. Yoshioka, S. Nakamura, T. Sato, S. Yokota, H. Yamaguchi
- Organizer
  アメリカ微生物学会 ASM Worl Microbe Forum (オンライン開催)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20613
[Presentation] Interaction between Legionella pneumophila and ciliates isolated from sewage and a sink trap2021
- Author(s)
  Kawashiro Airi, Onuma Reiji, Okubo Torahiko, Thapa Jeewan, Yamaguchi Hiroyuki
- Organizer
  World Microbe Forum
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K19403
[Presentation] Wild ciliates isolated from sewage or sink trap sludge using a handmade maze device differ in susceptibility to Legionella pneumophila2021
- Author(s)
  A. Kawashiro, R. Onuma, T. Okubo, J. Thapa, S. Nakamura, H. Yamaguchi
- Organizer
  アメリカ微生物学会 ASM Worl Microbe Forum (オンライン開催)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20613
[Presentation] 下水およびシンクから採取した繊毛虫のLegionella pneumophila に対する感受性の検討2021
- Author(s)
  川代愛梨，玄行理子, 大久保寅彦，中村眞二，Jeewan Thapa, 山口博之
- Organizer
  第86回日本細菌学会北海道支部学術総会*国内地方(オンライン開催)
- Data Source
  KAKENHI-PROJECT-20K20613
[Presentation] 膣粘膜面のインドールとIFN-γ量の増加はクラミジア感染の制御に関わる2021
- Author(s)
  辻川諒哉、船橋悠希、大久保寅彦、タパジーワン、山口博之
- Organizer
  第94回日本細菌学会総会, オンライン
- Data Source
  KAKENHI-PROJECT-20K20613
[Presentation] 下水およびシンクから採取した繊毛虫の Legionella pneumophila に対する感受性の検討2021
- Author(s)
  川代愛梨、玄行理子、大久保寅彦、中村眞二、Jeewan Thapa、山口博之
- Organizer
  第86回日本細菌学会北海道支部学術総会
- Data Source
  KAKENHI-PROJECT-19K19403
[Presentation] 下水処理場からシリンジ分離法を用いて株化した繊毛虫とレジオネラの相互作用2021
- Author(s)
  川代愛梨, 大沼零士, 大久保寅彦, タパジーワン, 山口博之
- Organizer
  第94回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-19K19403
[Presentation] アメーバによる細菌運搬現象とNa+/Na+アンチポーターNhaAとのむ関係性の検証2021
- Author(s)
  大久保寅彦，田中菜那, Thapa Jeewan, 佐藤豊孝，横田伸一，山口博之
- Organizer
  第86回日本細菌学会北海道支部学術総会*国内地方(オンライン開催)
- Data Source
  KAKENHI-PROJECT-20K20613
[Presentation] A 3D-Printing Air Sampler Secured Air Flow Path in Collecting Airborne Live Bacteria2020
- Author(s)
  Okubo T, Sumi M, Thap J, Yamaguchi H
- Organizer
  アメリカ微生物学会 ASM Microbe2020 (ePoster)
- Data Source
  KAKENHI-PROJECT-20K20613
[Presentation] Hypoxia promotes Chlamydia trachomatis L2 growth via activation of the PI3K-AKT signal pathway and metabolic balance of NAD+/NADH ratio2020
- Author(s)
  Thapa J, Hashimoto K, Sugawara S, Tujikawa R, Okuboa T, Nakamura S, Yamaguchi H
- Organizer
  アメリカ微生物学会 ASM Microbe2020 (ePoster)
- Data Source
  KAKENHI-PROJECT-20K20613
[Presentation] Isolation of wild ciliates from sink trap sludge using a hand-made maze device with different susceptibility to Legionella pneumophila2020
- Author(s)
  Hasegawa T, Kawashiro A, Okubo T, Nakamura S, Thapa J, Yamaguchi H
- Organizer
  アメリカ微生物学会 ASM Microbe2020 (ePoster)
- Data Source
  KAKENHI-PROJECT-20K20613
[Presentation] A six-year analysis of poultry clinical bacterial infections reveals a worrying Antimicrobial resistance trend for Uganda.2019
- Author(s)
  Kakooza S, Munyiirwa D, Nabatta E, Eneku W, Wampande E, Kayaga E, Tumwebaze M, Afayoa M, Ssajjakambwe P, Tayebwa DS, Tsuchida S, Okubo T, Ushida K, Muwonge A, Mutebi F.
- Organizer
  The 4th National Antimicrobial Resistance Conference.　Ministry of Health The Republic of Uganda
- Data Source
  KAKENHI-PROJECT-16H02767
[Presentation] マンホール下水からのESBL産生菌分離を下水由来繊毛虫を介したESBL遺伝子伝達の検証2019
- Author(s)
  長谷川貴生, 大久保寅彦, 山口博之
- Organizer
  第92回細菌学会総会
- Data Source
  KAKENHI-PROJECT-19K19403
[Presentation] Staphylococcus aureus prompts Escherichia coli survival under dry conditions: A potential threat from the viewpoint of nosocomial infection2018
- Author(s)
  T. Okubo, T. Shimoda, R. Yano, S. Nakamura, J. Matsuo, H. Yamaguchi
- Organizer
  ASM Microbe 2018(Atlanta, USA)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05225
[Presentation] 札幌地下歩行空間における空気中浮遊細菌叢の解析: 通行人は浮遊菌叢に影響を与える.2018
- Author(s)
  渡辺宜典、大久保寅彦、大崎敬子、松尾淳司、神谷茂、山口博之
- Organizer
  第91回日本細菌学会総会(福岡)
- Data Source
  KAKENHI-PROJECT-16K15270
[Presentation] 繊毛虫はヒト病原細菌と水系環境細菌を双方向的な薬剤耐性プラスミドの接合伝達の促進作用を介して結ぶ2018
- Author(s)
  松下瑞江, 松尾淳司, 大久保寅彦, 山口博之
- Organizer
  第91回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-16K19113
[Presentation] Chlamydia trachomatisは、感染後期に宿主細胞のカスパーゼ3を活性化する.2018
- Author(s)
  松尾淳司、大久保寅彦、中村眞二、山口博之
- Organizer
  第91回日本細菌学会総会(福岡)
- Data Source
  KAKENHI-PROJECT-16K15270
[Presentation] 病院で用いられる乾燥床材上における細菌間の鬩ぎ合い: 残存生菌数とATP量のギャップから紐解く細菌の生存戦略.2018
- Author(s)
  大久保寅彦、中村眞二、松尾淳司、山口博之
- Organizer
  第91回日本細菌学会総会. 福岡
- Data Source
  KAKENHI-PROJECT-16H05225
[Presentation] 繊毛虫はヒト病原細菌と水系環境細菌を双方向的な薬剤耐性プラスミドの接合伝達の促進作用を介して結ぶ.2018
- Author(s)
  松下瑞江、松尾淳司、大久保寅彦、山口博之
- Organizer
  第91回日本細菌学会総会(福岡)
- Data Source
  KAKENHI-PROJECT-16K15270
[Presentation] Subtle change of host-cell density causes fatal error on monitoring the intracellular growth of Chlamydia trachomatis in a low-oxygen environment.2018
- Author(s)
  K. Sakai, J. Matsuo, T. Okubo, S. Nakamura, H. Yamaguchi
- Organizer
  ASM Microbe 2018(Atlanta, USA)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05225
[Presentation] 低酸素環境においてChlamydia trachomatisの感染動態を修飾する要因: 感染実験の成否を握る鍵は何か.2018
- Author(s)
  酒井昂平、松尾淳司、渡辺宜典、大久保寅彦、中村眞二、山口博之
- Organizer
  第91回日本細菌学会総会. 福岡
- Data Source
  KAKENHI-PROJECT-16H05225
[Presentation] Cyclic Luciferase Probe Reveals Caspase-3 Activation in Chlamydia-Infected Cells At Late Times During Infection.2018
- Author(s)
  J. Matsuo, S. Haga, T. Okubo, S. Nakamura, T. Ozawa, M. Ozaki, H. Yamaguchi
- Organizer
  ASM Microbe 2018(Atlanta, USA)
- Data Source
  KAKENHI-PROJECT-16K15270
[Presentation] Chlamydia trachomatisは、感染後期に宿主細胞のカスパーゼ3を活性化する.2018
- Author(s)
  松尾淳司、大久保寅彦、中村眞二、山口博之
- Organizer
  第91回日本細菌学会総会. 福岡
- Data Source
  KAKENHI-PROJECT-16H05225
[Presentation] Ciliates promote the interactive transfer of plasmid encoding blaNDM-5 between human pathogenic Escherichia coli and environmental Aeromonas caviae.2018
- Author(s)
  M. Matsushita, T. Okubo, J. Matsuo, S. Nakamura, H. Yamaguchi
- Organizer
  ASM Microbe 2018(Atlanta, USA)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05225
[Presentation] 1.T. Okubo, T. Shimoda, R. Yano, S. Nakamura, J. Matsuo, H. Yamaguchi: Staphylococcus aureus prompts Escherichia coli survival under dry conditions: A potential threat from the viewpoint of nosocomial infection.2018
- Author(s)
  T. Okubo, T. Shimoda, R. Yano, S. Nakamura, J. Matsuo, H. Yamaguchi
- Organizer
  ASM Microbe 2018(Atlanta, USA)
- Data Source
  KAKENHI-PROJECT-16K15270
[Presentation] 低酸素環境においてChlamydia trachomatisの感染動態を修飾する要因: 感染実験の成否を握る鍵は何か.2018
- Author(s)
  酒井昂平、松尾淳司、渡辺宜典、大久保寅彦、中村眞二、山口博之
- Organizer
  第91回日本細菌学会総会(福岡)
- Data Source
  KAKENHI-PROJECT-16K15270
[Presentation] Ciliates promote the interactive transfer of plasmid encoding blaNDM-5 between human pathogenic Escherichia coli and environmental Aeromonas caviae.2018
- Author(s)
  M. Matsushita, T. Okubo, J. Matsuo, S. Nakamura, H. Yamaguchi
- Organizer
  ASM Microbe 2018(Atlanta, USA)
- Data Source
  KAKENHI-PROJECT-16K15270
[Presentation] Cyclic Luciferase Probe Reveals Caspase-3 Activation in Chlamydia-Infected Cells At Late Times During Infection.2018
- Author(s)
  J. Matsuo, S. Haga, T. Okubo, S. Nakamura, T. Ozawa, M. Ozaki, H. Yamaguchi
- Organizer
  ASM Microbe 2018(Atlanta, USA)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05225
[Presentation] 札幌地下歩行空間における空気中浮遊細菌叢の解析: 通行人は浮遊菌叢に影響を与える.2018
- Author(s)
  渡辺宜典、大久保寅彦、大崎敬子、松尾淳司、神谷茂、山口博之
- Organizer
  第91回日本細菌学会総会. 福岡
- Data Source
  KAKENHI-PROJECT-16H05225
[Presentation] Subtle change of host-cell density causes fatal error on monitoring the intracellular growth of Chlamydia trachomatis in a low-oxygen environment.2018
- Author(s)
  K. Sakai, J. Matsuo, T. Okubo, S. Nakamura, H. Yamaguchi
- Organizer
  ASM Microbe 2018(Atlanta, USA)
- Data Source
  KAKENHI-PROJECT-16K15270
[Presentation] 繊毛虫はヒト病原細菌と水系環境細菌を双方向的な薬剤耐性プラスミドの接合伝達の促進作用を介して結ぶ.2018
- Author(s)
  松下瑞江、松尾淳司、大久保寅彦、山口博之
- Organizer
  第91回日本細菌学会総会. 福岡
- Data Source
  KAKENHI-PROJECT-16H05225
[Presentation] Amoebae backpack human pathogenic bacteria on solid-agar plate, depending upon the amoebal endosymbiont, Neochlamydia2017
- Author(s)
  T. Okubo, M. Matsushita, J. Matsuo, S. Nakamura, H. Yamaguchi
- Organizer
  ASM microbe 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05225
[Presentation] 病院で用いられる乾燥床材上における細菌間の鬩ぎ合い: 残存生菌数とATP量のギャップから紐解く細菌の生存戦略2017
- Author(s)
  大久保寅彦、中村眞二、松尾淳司、山口博之
- Organizer
  第91回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-16K15270
[Presentation] Aboebae backpack human pathogenic bacteria on solid-agar plate, depending upon the amoebal endosymbiont, Neochlamydia2017
- Author(s)
  Okubo T, Matsushita M, Matsuo J, Nakamura S, Yamaguchi H
- Organizer
  アメリカ微生物学会学術集会(ASM Microbe 2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19113
[Presentation] 繊毛虫やアメーバと細菌(環境クラミジアを含む)との鬩ぎ合いから紐解く微生物間相互作用2017
- Author(s)
  山口博之、大久保寅彦、松尾淳司
- Organizer
  第35回日本クラミジア研究会
- Invited
- Data Source
  KAKENHI-PROJECT-16K15270
[Presentation] Endosymbiotic bacterium Neochlamydia restricts host amoebal phagocytosis via actin stabilization, resulting in the defense of the host amoebae against Legionella infection2017
- Author(s)
  M. Matsushita, C. Maita, T. Okubo, J. Matsuo, S. Nakamura, H. Nagai, H. Yamaguchi
- Organizer
  ASM microbe 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15270
[Presentation] Synergistic effect of walkers with other factors on changing airborne bacterial communities in a built environment, Sapporo underground pedestrian space2017
- Author(s)
  K. Sakai, T. Okubo, J. Matsuo, S. Nakamura, H. Yamaguchi
- Organizer
  ASM microbe 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15270
[Presentation] 繊毛虫やアメーバと細菌(環境クラミジアを含む)との鬩ぎ合いから紐解く微生物間相互作用2017
- Author(s)
  山口博之、大久保寅彦、松尾淳司
- Organizer
  第35回日本クラミジア研究会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05225
[Presentation] Impact of Protozoa-related Giant Viruses on Environmental Chlamydial Evolution with Divergent in the Amoebal Niche2017
- Author(s)
  Hiroyuki Yamaguchi, Sumire Yamazaki, Junji Matsuo, Torahiko Okubo
- Organizer
  ASM microbe 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15270
[Presentation] Degree of virginal inflammation has minimal impact on the prevalence of Chlamydia trachomatis infection on female genital tract2017
- Author(s)
  J. Matsuo, K. Taki, T. Okubo, K. Abe, K. Minami, H. Yamaguchi
- Organizer
  ASM microbe 2017
- Invited
- Data Source
  KAKENHI-PROJECT-16H05225
[Presentation] 共生細菌依存的なアメーバによるヒト病原細菌の運搬現象について2017
- Author(s)
  松下瑞江, 大久保寅彦, 松尾淳司, 中村眞二, 山口博之
- Organizer
  第84回日本細菌学会北海道支部学術総会
- Data Source
  KAKENHI-PROJECT-16K19113
[Presentation] Amoebae backpack human pathogenic bacteria on solid-agar plate, depending upon the amoebal endosymbiont, Neochlamydia2017
- Author(s)
  T. Okubo, M. Matsushita, J. Matsuo, S. Nakamura, H. Yamaguchi
- Organizer
  ASM microbe 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15270
[Presentation] 低酸素環境における Chlamydia trachomatis 感染細胞の遺伝子発現解析2017
- Author(s)
  ○酒井昂平，松尾淳司，山川和也，大久保寅彦，中村眞二，山口博之
- Organizer
  第90回日本細菌学会総会
- Place of Presentation
  仙台国際センター展示棟（宮城県仙台市）
- Year and Date
  2017-03-19
- Data Source
  KAKENHI-PROJECT-16H05225
[Presentation] Endosymbiotic bacterium Neochlamydia restricts host amoebal phagocytosis via actin stabilization, resulting in the defense of the host amoebae against Legionella infection2017
- Author(s)
  M. Matsushita, C. Maita, T. Okubo, J. Matsuo, S. Nakamura, H. Nagai, H. Yamaguchi
- Organizer
  ASM microbe 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05225
[Presentation] 繊毛虫はヒト病原細菌と水系環境細菌を双方向的な薬剤耐性プラスミドの接合伝達の促進作用を介して結ぶ2017
- Author(s)
  松下瑞江、松尾淳司、大久保寅彦、山口博之
- Organizer
  第91回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-16K15270
[Presentation] 病院で用いられる乾燥床材上における細菌間の鬩ぎ合い: 残存生菌数とATP量のギャップから紐解く細菌の生存戦略2017
- Author(s)
  大久保寅彦、中村眞二、松尾淳司、山口博之
- Organizer
  第91回日本細菌学会総
- Data Source
  KAKENHI-PROJECT-16H05225
[Presentation] 札幌地下歩行空間における空気中浮遊細菌叢の解析: 通行人は浮遊菌叢に影響を与える2017
- Author(s)
  渡辺宜典、大久保寅彦、大崎敬子、松尾淳司、神谷茂、山口博之
- Organizer
  第91回日本細菌学会総
- Data Source
  KAKENHI-PROJECT-16H05225
[Presentation] Chlamydia trachomatisは感染後期に宿主細胞のカスパーゼ3を活性化する2017
- Author(s)
  松尾淳司、大久保寅彦、中村眞二、山口博之
- Organizer
  第91回日本細菌学会総
- Data Source
  KAKENHI-PROJECT-16H05225
[Presentation] アメーバ共生細菌 Neochlamydia S13 はアクチンの安定化を介して宿主アメーバの貪食能を制限している2017
- Author(s)
  ○米田千夏，松尾淳司，大久保寅彦，中村眞二，永井宏樹，山口博之
- Organizer
  第90回日本細菌学会総会
- Place of Presentation
  仙台国際センター　宮城県　仙台市
- Year and Date
  2017-03-19
- Data Source
  KAKENHI-PROJECT-16K15270
[Presentation] 北海道大学病院にて分離されたNDM産生大腸菌の性状解析と繊毛虫によるプラスミド伝達の促進2017
- Author(s)
  大久保寅彦, 松下瑞江, 松尾淳司, 山口博之
- Organizer
  第90回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-16K19113
[Presentation] Impact of Protozoa-related Giant Viruses on Environmental Chlamydial Evolution with Divergent in the Amoebal Niche2017
- Author(s)
  Hiroyuki Yamaguchi, Sumire Yamazaki, Junji Matsuo, Torahiko Okubo
- Organizer
  ASM microbe 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05225
[Presentation] Synergistic effect of walkers with other factors on changing airborne bacterial communities in a built environment, Sapporo underground pedestrian space2017
- Author(s)
  K. Sakai, T. Okubo, J. Matsuo, S. Nakamura, H. Yamaguchi
- Organizer
  ASM microbe 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05225
[Presentation] 繊毛虫はヒト病原細菌と水系環境細菌をによる水系環境菌への双方向的な薬剤耐性プラスミドの接合伝達の促進作用を介して結ぶ2017
- Author(s)
  松下瑞江、松尾淳司、大久保寅彦、山口博之
- Organizer
  第91回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-16H05225
[Presentation] 札幌地下歩行空間における空気中浮遊細菌叢の解析: 通行人は浮遊菌叢に影響を与える2017
- Author(s)
  渡辺宜典、大久保寅彦、大崎敬子、松尾淳司、神谷茂、山口博之
- Organizer
  第91回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-16K15270
[Presentation] 低酸素環境においてChlamydia trachomatisの感染動態を修飾する要因: 感染実験の成否を握る鍵は何か2017
- Author(s)
  酒井昂平、松尾淳司、渡辺宜典、大久保寅彦、中村眞二、山口博之
- Organizer
  第91回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-16K15270
[Presentation] Chlamydia trachomatisは、感染後期に宿主細胞のカスパーゼ3を活性化する2017
- Author(s)
  松尾淳司、大久保寅彦、中村眞二、山口博之
- Organizer
  第91回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-16K15270
[Presentation] Degree of virginal inflammation has minimal impact on the prevalence of Chlamydia trachomatis infection on female genital tract2017
- Author(s)
  J. Matsuo, K. Taki, T. Okubo, K. Abe, K. Minami, H. Yamaguchi
- Organizer
  ASM microbe 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15270
[Presentation] 流通生鮮鶏肉表面上での細菌と原生動物のせめぎ合い：メタゲノム解析による菌叢変化と鞭毛虫の株化2016
- Author(s)
  大久保寅彦、松尾淳司、山口博之
- Organizer
  第89回日本細菌学会総会
- Place of Presentation
  大阪国際交流センター（大阪府大阪市）
- Year and Date
  2016-03-23
- Data Source
  KAKENHI-PROJECT-15H05997
[Presentation] 流通生鮮鶏肉表面上における食中毒菌と原生動物のせめぎ合いの検証2016
- Author(s)
  大久保寅彦、松尾淳司、山口博之
- Organizer
  第90回日本感染症学会・学術集会
- Place of Presentation
  仙台国際センター・新展示施設（宮城県仙台市）
- Year and Date
  2016-04-15
- Data Source
  KAKENHI-PROJECT-15H05997

1. Yamaguchi Hiroyuki (40221650)

# of Collaborated Projects: 8 results

# of Collaborated Products: 112 results
2. NAKAMURA Shinji (40207882)

# of Collaborated Projects: 5 results

# of Collaborated Products: 46 results
3. MATSUO Junji (50359486)

# of Collaborated Projects: 3 results

# of Collaborated Products: 61 results
4. 矢野理香 (50250519)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
5. 宇野智子 (60576180)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. USHIDA Kazunari (50183017)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. Sato Toyotaka (30756474)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. 浅井鉄夫 (10509764)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 丸山史人 (30423122)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. 大屋賢司 (50402219)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. 岩破一博 (30223390)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 大森亮介 (10746952)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. 浦野恵美子 (40794988)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 青木弘太郎 (50821914)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 中島千絵 (60435964)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 臼井優 (60639540)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
17. 鈴木仁人 (70444073)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 福田昭 (90827320)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
19. 小笠原徳子 (00438061)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 山本聡 (10588479)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 渡辺玲奈 (10431313)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. THAPA JEEWAN (40837449)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
23. MATSUSHITA Mizue

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
24. AKIZAWA Kouji

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. HAYASAKA Kasumi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. FUKUMOTO Tatsuya

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. IWASAKI Sumio

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. YOKOTA Shin-ichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. KAMIYA Shigeru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 大さき敬子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Okubo Torahiko 大久保 寅彦

Research Projects

Research Products

Co-Researchers

パンデミッククローンST131をモデルとした大腸菌臨床株の乾燥抵抗性メカニズムの解明Principal Investigator

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Functional elucidation of novel effectors of Legionella pneumophila approached through interactions with unique ciliatePrincipal Investigator

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Dissemination of antimicrobial-resistant bacteria from hospital sewage to natural environmentsPrincipal Investigator

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Effect of bacterial signal molecule AI-2 on the metabolism and pathogenicity of protozoaPrincipal Investigator

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市販鶏肉の表面で繰り広げられる細菌と原生動物の相互作用の可視化と応用Principal Investigator

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[Journal Article] Differential impact of environmental factors on airborne live bacteria and inorganic particles in an underground walkway2024

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[Journal Article] Human pathogenic bacteria on high-touch dry surfaces can be controlled by warming to human-skin temperature under moderate humidity2023

Okubo Torahiko 大久保寅彦