Jun Toda 戸田淳

Researcher Number	90770834
Other IDs
Affiliation (based on the past Project Information) *help	2022 – 2023: 大阪大学, 大学院医学系研究科, 招へい教員 2021: 大阪大学, 医学系研究科, 特任助教(常勤) 2016 – 2021: 大阪大学, 医学部附属病院, 医員
Review Section/Research Field	Principal Investigator Basic Section 54010:Hematology and medical oncology-related Except Principal Investigator Basic Section 54010:Hematology and medical oncology-related / Hematology
Keywords	Principal Investigator STAP / STAP蛋白 / MPN / BCR-ABL / CML幹細胞 / CML / アダプター蛋白 / STAP-1 / 白血病幹細胞 / 慢性骨髄性白血病 … More Except Principal Investigator … More GVHD / STAP / 免疫再構築 / 胸腺再生 / STAP蛋白 / リンパ球 / 同種移植 / 同種造血幹細胞移植 / 骨髄微小環境 / 間葉系幹細胞 / 微小環境 / 造血微小環境 / 多発性骨髄腫 / 内科 / 免疫学 / 蛋白質 / 遺伝子 / T細胞受容体 / 炎症反応 / シグナル伝達 / 腫瘍化 / 免疫反応 / 造血幹細胞移植 / 移植片対宿主病 / 慢性骨髄性白血病 / 免疫応答 / アダプター蛋白 Less

Functional analysis of STAP, a signal-regulating molecule, in clonal expansion of myeloproliferative tumor stem cellsPrincipal Investigator
- Principal Investigator
  
  Toda Jun
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Osaka University
Role of mesenchymal stromal cells in multiple myeloma
- Principal Investigator
  
  Ichii Michiko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Osaka University
Role of STAP proteins in allogeneic hematopoietic stem cell transplantation
- Principal Investigator
  
  Saitoh Hideaki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Osaka University
Functional analysis of STAP family proteins in CMLPrincipal Investigator
- Principal Investigator
  
  Jun Toda
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Osaka University
Analysis of regulation of signals by STAP adaptor protein in immune system and tumorigenesis
- Principal Investigator
  
  ORITANI KENJI
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  International University of Health and Welfare
  Osaka University

All 2024 2022 2021 2020 2019 2018 2017

All Journal Article Presentation

[Journal Article] Role of Signal-Transducing Adaptor Protein-1 for T Cell Activation and Pathogenesis of Autoimmune Demyelination and Airway Inflammation2024
- Author(s)
  Kagohashi Kota、Sasaki Yuto、Ozawa Kiyotaka、Tsuchiya Takuya、Kawahara Shoya、Saitoh Kodai、Ichii Michiko、Toda Jun、Harada Yasuyo、Kubo Masato、Kitai Yuichi、Muromoto Ryuta、Oritani Kenji、Kashiwakura Jun-ichi、Matsuda Tadashi
- Journal Title
  
  The Journal of Immunology
  
  Volume: 212 Issue: 6 Pages: 951-961
- DOI
  10.4049/jimmunol.2300202
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K18170, KAKENHI-PROJECT-23K07812, KAKENHI-PROJECT-21K08451, KAKENHI-PROJECT-21K16243
[Journal Article] Signal-transducing adaptor protein-1 and protein-2 in hematopoiesis and diseases2022
- Author(s)
  Ichii, Michiko; Oritani, Kenji; Toda, Jun; Hosen, Naoki; Matsuda, Tadashi; Kanakura, Yuzuru
- Journal Title
  
  Experimental Hematology
  
  Volume: 105 Pages: 10-17
- DOI
  10.1016/j.exphem.2021.11.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03364, KAKENHI-PROJECT-21K16243
[Journal Article] High numbers of programmed cell death-1-positive tumor infiltrating lymphocytes correlate with early onset of post-transplant lymphoproliferative disorder2021
- Author(s)
  Saito Hideaki、Miyoshi Hiroaki、Shibayama Hirohiko、Toda Jun、Kusakabe Shinsuke、Ichii Michiko、Fujita Jiro、Fukushima Kentaro、Maeda Tetsuo、Mizuki Masao、Oritani Kenji、Seto Masao、Yokota Takafumi、Kanakura Yuzuru、Hosen Naoki、Ohshima Koichi
- Journal Title
  
  International Journal of Hematology
  
  Volume: - Issue: 1 Pages: 53-64
- DOI
  10.1007/s12185-021-03129-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K17401, KAKENHI-PROJECT-19K08815, KAKENHI-PROJECT-19K08861
[Journal Article] Graft-versus-host disease develops in mice transplanted with lymphocyte-depleted bone marrow cells from signal-transducing adaptor protein-2 transgenic mice2021
- Author(s)
  Saito H, Ichii M, Toda J, Kitai Y, Muromoto R, Kashiwakura JI, Saitoh K, Tanimura A, Yokota T, Shibayama H, Matsuda T, Oritani K, Kanakura Y, Hosen N.
- Journal Title
  
  Biochem Biophys Res Commun .
  
  Volume: 537 Pages: 118-124
- DOI
  10.1016/j.bbrc.2020.12.080
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08815, KAKENHI-PROJECT-19K08861, KAKENHI-PROJECT-19H03364, KAKENHI-PROJECT-18K08355
[Journal Article] Positive interactions between STAP-1 and BCR-ABL influence chronic myeloid leukemia cell proliferation and survival2021
- Author(s)
  Ishiura, Marie; Kitai, Yuichi; Kashiwakura, Jun-ichi; Muromoto, Ryuta; Toda, Jun; Ichii, Michiko; Oritani, Kenji; Matsuda, Tadashi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 556 Pages: 185-191
- DOI
  10.1016/j.bbrc.2021.03.162
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03364, KAKENHI-PROJECT-21K08451, KAKENHI-PROJECT-21K16243
[Journal Article] Signal-transducing adapter protein-1 is required for maintenance of leukemic stem cells in CML.2020
- Author(s)
  Toda J, Ichii M, Oritani K, Shibayama H, Tanimura A, Saito H, Yokota T, Motooka D, Okuzaki D, Kitai Y, Muromoto R, Kashiwakura JI, Matsuda T, Hosen N, Kanakura Y.
- Journal Title
  
  Oncogene
  
  Volume: 39 Issue: 34 Pages: 5601-5615
- DOI
  10.1038/s41388-020-01387-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08861, KAKENHI-PROJECT-20K08356, KAKENHI-PROJECT-19H03364, KAKENHI-PROJECT-20H03710, KAKENHI-PROJECT-18K08355, KAKENHI-PROJECT-19K17829
[Journal Article] Signal-transducing adaptor protein-2 delays recovery of B lineage lymphocytes during hematopoietic stress2020
- Author(s)
  Ichii Michiko、Oritani Kenji、Toda Jun、Saito Hideaki、Shi Henyun、Shibayama Hirohiko、Motooka Daisuke、Kitai Yuichi、Muromoto Ryuta、Kashiwakura Jun-ichi、Saitoh Kodai、Okuzaki Daisuke、Matsuda Tadashi、Kanakura Yuzuru
- Journal Title
  
  Haematologica
  
  Volume: in press Issue: 2 Pages: 225573-225573
- DOI
  10.3324/haematol.2019.225573
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08815, KAKENHI-PROJECT-18K14893, KAKENHI-PROJECT-19H03364, KAKENHI-PROJECT-19K08861, KAKENHI-PROJECT-19K17829
[Presentation] Signal transducing adaptor protein (STAP)-2 accelerates graft-versus-host-disease2020
- Author(s)
  Hideaki Saito，Michiko Ichii，Jun Toda，Yuichi Kitai，Ryuta Muromoto，Junichi Kashiwakura，Kodai Saitoh，Takafumi Yokota，Hirohiko Shibayama，Tadashi Matsuda，Kenji Oritani，Yuzuru Kanakura，Naoki Hosen.
- Organizer
  第82回日本血液学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-19K08815
[Presentation] STAP-1 is Required for Maintenance of Leukemic Stem Cells in Chronic Myeloid Leukemia.2019
- Author(s)
  Jun Toda, Michiko Ichii, Kenji Oritani, Hideaki Saito, Yuichi Kitai, Ryuta Muromoto, Jun-ichi Kashiwakura, Kodai Saitoh, Tadashi Matsuda, Yuzuru Kanakura
- Organizer
  JSH international symposium 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17829
[Presentation] Therapeutic potential of the signal-transducing adaptor protein-1 (STAP-1) inhibition for CML treatment2019
- Author(s)
  Jun Toda, Michiko Ich, Hirohiko Shibayama, Hideaki Saito, Tadashi Matsuda, Kenji Oritani, and Yuzuru Kanakura
- Organizer
  日本血液学会 2019
- Data Source
  KAKENHI-PROJECT-19K17829
[Presentation] 慢性骨髄性白血病におけるSTAPファミリー蛋白の役割2018
- Author(s)
  戸田　淳, 一井倫子, 西東秀晃, 鍛代悠一,室本竜太, 柏倉淳一, 齋藤浩大, 柴山浩彦, 松田　正, 織谷健司, 金倉　譲
- Organizer
  第80回日本血液学会学術集会（2018.10.12-14, 大阪国際会議場, 大阪, 松村到）
- Data Source
  KAKENHI-PROJECT-16K09872
[Presentation] 骨髄内B細胞分化におけるSTAP-2蛋白の役割2018
- Author(s)
  一井倫子, 織谷健司, 柴山浩彦, 戸田　淳, 西東秀晃, 北井勇一, 室本竜太, 柏倉淳一, 齋藤浩大, 松田　正, 金倉　譲
- Organizer
  第80回日本血液学会学術集会（2018.10.12-14, 大阪国際会議場, 大阪, 松村到）
- Data Source
  KAKENHI-PROJECT-16K09872
[Presentation] Signal transducing adaptor protein-2(STAP-2)はマウスモデルで慢性GVHDを悪化させる2018
- Author(s)
  西東秀晃, 一井倫子,戸田　淳, 鍛代悠一, 室本竜太, 柏倉淳一, 齋藤浩大, 柴山浩彦, 松田　正, 織谷健司, 金倉　譲
- Organizer
  第80回日本血液学会学術集会（2018.10.12-14, 大阪国際会議場, 大阪, 松村到）
- Data Source
  KAKENHI-PROJECT-16K09872
[Presentation] Role of Signal Transducing Adaptor Protein-1 (STAP-1) in Chronic Myelogenous Leukemia.2018
- Author(s)
  Jun Toda, Michiko Ichii, Kenji Oritani, Hideaki Saito, Yuichi Kitai, Ryuta Muromoto, Jun-ichi Kashiwakura, Kodai Saitoh, Tadashi Matsuda, Yuzuru Kanakura
- Organizer
  The American Society of Hematology 60th Annual Meeting (2018.12.1-4, San Diego Convention Center, CA, USA)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09872
[Presentation] ATLL細胞はCD39を高発現し、Adenosine経路を介して免疫応答を抑制する2018
- Author(s)
  長手泰宏, 江副幸子, 藤田二郎, 横田貴史, 一井倫子, 谷村　朗, 濱中　有理, 土居由貴子, 上田智朗, 戸田淳, 柴山浩彦, 織谷健司, 金倉　譲
- Organizer
  第80回日本血液学会学術集会（2018.10.12-14, 大阪国際会議場, 大阪, 松村到）
- Data Source
  KAKENHI-PROJECT-16K09872
[Presentation] Signal Transducing Adaptor Protein (STAP) Family Accelerates Gut and Thymic Graft-Versus-Host-Disease in Murine Model.2018
- Author(s)
  Hideaki Saito, Michiko Ichii, Jun Toda, Yuichi Kitai, Ryuta Muromoto, Jun-ichi Kashiwakura, Kodai Saitoh, Hirohiko Shibayama, Tadashi Matsuda, Kenji Oritani, Yuzuru Kanakura
- Organizer
  The American Society of Hematology 60th Annual Meeting (2018.12.1-4, San Diego Convention Center, CA, USA)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09872
[Presentation] Ectonucleosidase CD39 Is Highly Expressed on ATLL Cells and Suppresses the Immune Response through theAdenosine Pathway.2018
- Author(s)
  Yasuhiro Nagate, Sachiko Ezoe, Jiro Fujita, Takafumi Yokota, Michiko Ichii, Akira Tanimura, Yukiko Doi, Tomoaki Ueda, Jun Toda, Hirohiko Shibayama, Kenji Oritani, Yuzuru Kanakura
- Organizer
  The American Society of Hematology 60th Annual Meeting (2018.12.1-4, San Diego Convention Center, CA, USA)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09872
[Presentation] Role of Signal Transducing Adaptor Protein (STAP) Family in Chronic Myelogenous Leukemia.2017
- Author(s)
  Toda J, Ichii M, Shibayama H, Saito H, Kitai Y, Muromoto R, Kashiwakura J, Saitoh K, Matsuda T, Oritani K, Kanakura Y
- Organizer
  The American Society of Hematology 59th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09872
[Presentation] 慢性骨髄性白血病の進展におけるアダプター蛋白STAP-1の役割2017
- Author(s)
  Toda J, Ichii M, Oritani K, Saito H, Kitai Y, Muromoto R, Kashiwakura J, Saitoh K, Matsuda T, Kanakura Y
- Organizer
  第79回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09872
[Presentation] Signal-Transducing Adaptor Protein-2 Blocks B cell Recovery under Hematological Stress at pre-B stage via TLR4 Signaling.2017
- Author(s)
  Ichii M, Oritani K, Shibayama H, Toda J, Saito H, Kitai Y, Muromoto R, Kashiwakura J, Saitoh K, Matsuda T, Kanakura Y
- Organizer
  The American Society of Hematology 59th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09872
[Presentation] STAP-2 is an adopter molecule to positively regulate basophil activation2017
- Author(s)
  Jun-ichi Kashiwakura, Shinsuke Yamashita, Kodai Saitoh, Kenji Oritani and Tadashi Matsuda
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09872
[Presentation] Signal transducing adaptor protein-1(STAP-1)maintains chronic myeloid leukemic stem cells.2017
- Author(s)
  Toda J, Ichii M, Oritani K, Saito H, Kitai Y, Muromoto R, Kashiwakura J, Saitoh K, Matsuda T, Kanakura Y
- Organizer
  22nd Congress of the European Hematology Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09872

1. Ichii Michiko (30633010)

# of Collaborated Projects: 3 results

# of Collaborated Products: 14 results
2. Saitoh Hideaki (50815496)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
3. 柴山浩彦 (60346202)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
4. ORITANI KENJI (70324762)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
5. 前田哲生 (00403064)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 金倉譲 (20177489)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
7. MUROMOTO Ryuta

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
8. YOKOTA Takahumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 草壁信輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 松田正

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
11. 鍛代悠一

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
12. 柏倉淳一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Jun Toda 戸田 淳

Research Projects

Research Products

Co-Researchers

Functional analysis of STAP, a signal-regulating molecule, in clonal expansion of myeloproliferative tumor stem cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role of mesenchymal stromal cells in multiple myeloma

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role of STAP proteins in allogeneic hematopoietic stem cell transplantation

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functional analysis of STAP family proteins in CMLPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of regulation of signals by STAP adaptor protein in immune system and tumorigenesis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Role of Signal-Transducing Adaptor Protein-1 for T Cell Activation and Pathogenesis of Autoimmune Demyelination and Airway Inflammation2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Signal-transducing adaptor protein-1 and protein-2 in hematopoiesis and diseases2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] High numbers of programmed cell death-1-positive tumor infiltrating lymphocytes correlate with early onset of post-transplant lymphoproliferative disorder2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Graft-versus-host disease develops in mice transplanted with lymphocyte-depleted bone marrow cells from signal-transducing adaptor protein-2 transgenic mice2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Positive interactions between STAP-1 and BCR-ABL influence chronic myeloid leukemia cell proliferation and survival2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Signal-transducing adapter protein-1 is required for maintenance of leukemic stem cells in CML.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Signal-transducing adaptor protein-2 delays recovery of B lineage lymphocytes during hematopoietic stress2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] Signal transducing adaptor protein (STAP)-2 accelerates graft-versus-host-disease2020

Author(s)

Organizer

Data Source

[Presentation] STAP-1 is Required for Maintenance of Leukemic Stem Cells in Chronic Myeloid Leukemia.2019

Author(s)

Organizer

Data Source

[Presentation] Therapeutic potential of the signal-transducing adaptor protein-1 (STAP-1) inhibition for CML treatment2019

Author(s)

Organizer

Jun Toda 戸田淳