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Matsusaki Motonori  松崎 元紀

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MATSUSAKI Motonori  松崎 元紀

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Researcher Number 90817040
Other IDs
Affiliation (Current) 2025: 徳島大学, 先端酵素学研究所, 助教
Affiliation (based on the past Project Information) *help 2020 – 2024: 徳島大学, 先端酵素学研究所, 助教
2020: 東北大学, 学際科学フロンティア研究所, 特別研究員(PD)
2019: 東北大学, 多元物質科学研究所, 特別研究員(PD)
Review Section/Research Field
Principal Investigator
Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related / Complex systems / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
Except Principal Investigator
Medium-sized Section 37:Biomolecular chemistry and related fields / Basic Section 43020:Structural biochemistry-related
Keywords
Principal Investigator
小胞体ストレス応答 / IRE1 / ジスルフィド結合 / タンパク質品質管理 / 小胞体 / 小胞体ストレスセンサー / ミスフォールドタンパク質 / PDIファミリー / 情報熱力学 / インスリン … More
Except Principal Investigator
… More 蛋白質品質管理 / メゾスケール構造体 / 分泌経路 / セクレトーム解析 / NMR / 立体構造 / 結合キネティクス / タンパク質フォールディング / シャペロン Less
  • Research Projects

    (6 results)
  • Research Products

    (28 results)
  • Co-Researchers

    (7 People)
  •  分泌経路におけるメゾスケール構造体プロファイリングの開拓

    • Principal Investigator
      奥村 正樹
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Fund for the Promotion of Joint International Research (International Collaborative Research)
    • Review Section
      Medium-sized Section 37:Biomolecular chemistry and related fields
    • Research Institution
      Tohoku University
  •  Multidimensional endoplasmic reticulum stress sensing by IRE1Principal Investigator

    • Principal Investigator
      MATSUSAKI Motonori
    • Project Period (FY)
      2022 – 2023
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
    • Research Institution
      The University of Tokushima
  •  細胞内ストレス応答の情報熱力学的な理解Principal Investigator

    • Principal Investigator
      松崎 元紀
    • Project Period (FY)
      2022 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Complex systems
    • Research Institution
      The University of Tokushima
  •  Mechanism of chaperone activity modulation through promiscuous recognitions

    • Principal Investigator
      齋尾 智英
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 43020:Structural biochemistry-related
    • Research Institution
      The University of Tokushima
  •  Molecular mechanism of disulfide-bonded active oligomerization by an endoplasmic stress sensor IRE1Principal Investigator

    • Principal Investigator
      MATSUSAKI Motonori
    • Project Period (FY)
      2020 – 2021
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
    • Research Institution
      The University of Tokushima
  •  Molecular mechanism of ER stress response regulation by PDI family proteinsPrincipal Investigator

    • Principal Investigator
      松崎 元紀
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for JSPS Fellows
    • Review Section
      Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
    • Research Institution
      Tohoku University

All 2024 2023 2021 2020 2019

All Journal Article Presentation

  • [Journal Article] Client recognition differences between PDI and ERp46 to guide oxidative folding2024

    • Author(s)
      Saio Tomohide、Ishii Kotone、Matsusaki Motonori、Kumeta Hiroyuki、Kanemura Shingo、Okumura Masaki
    • Journal Title

      bioRxiv

      Volume: 2024.03.04 Pages: 583432-583432

    • DOI

      10.1101/2024.03.04.583432

    • Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23KK0105, KAKENHI-PLANNED-21H05095
  • [Journal Article] A unique leucine-valine adhesive motif supports structure and function of protein disulfide isomerase P5 via dimerization2021

    • Author(s)
      Okumura M, Kanemura S., Matsusaki M., Kinoshita M., Saio T., Ito D., Hirayama C., Kumeta H., Watabe M., Amagai Y., Lee Y. H., Akiyama S. and Inaba K.
    • Journal Title

      Structure

      Volume: 29 Issue: 12 Pages: 1-14

    • DOI

      10.1016/j.str.2021.03.016

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K16092, KAKENHI-PROJECT-20K15969, KAKENHI-PROJECT-18H03978, KAKENHI-PROJECT-19J00893, KAKENHI-PROJECT-20J11932, KAKENHI-PROJECT-19K06520, KAKENHI-PUBLICLY-20H04688, KAKENHI-PLANNED-21H05095, KAKENHI-PROJECT-21H04758, KAKENHI-PUBLICLY-19H04945, KAKENHI-PLANNED-21H05253
  • [Journal Article] Conjugate of Thiol and Guanidyl Units with Oligoethylene Glycol Linkage for Manipulation of Oxidative Protein Folding2021

    • Author(s)
      Okada Shunsuke、Matsusaki Motonori、Okumura Masaki、Muraoka Takahiro
    • Journal Title

      Molecules

      Volume: 26 Issue: 4 Pages: 879-879

    • DOI

      10.3390/molecules26040879

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K15969, KAKENHI-PROJECT-19J00893, KAKENHI-PROJECT-19K06520, KAKENHI-PROJECT-19H02828, KAKENHI-PUBLICLY-20H04688, KAKENHI-PLANNED-21H05095
  • [Journal Article] Functional Interplay between P5 and PDI/ERp72 to Drive Protein Folding.2021

    • Author(s)
      Matsusaki M, Okada R, Tanikawa Y, Kanemura S, Ito D, Lin Y, Watabe M, Yamaguchi H, Saio T, Lee YH, Inaba K, and *Okumura M.
    • Journal Title

      Biology

      Volume: 10 Issue: 11 Pages: 1112-1112

    • DOI

      10.3390/biology10111112

    • NAID

      120007168792

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K06520, KAKENHI-PROJECT-19K16092, KAKENHI-PROJECT-20K15969, KAKENHI-PUBLICLY-20H04688, KAKENHI-PLANNED-21H05095, KAKENHI-PROJECT-21H04758, KAKENHI-PLANNED-21H05253
  • [Journal Article] Zinc-Dependent Oligomerization of Thermus thermophilus Trigger Factor Chaperone2021

    • Author(s)
      Zhu Haojie、Matsusaki Motonori、Sugawara Taiga、Ishimori Koichiro、Saio Tomohide
    • Journal Title

      Biology

      Volume: 10 Issue: 11 Pages: 1106-1106

    • DOI

      10.3390/biology10111106

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K15969, KAKENHI-PLANNED-19H05769, KAKENHI-PROJECT-18H05229
  • [Journal Article] Ca2+ Regulates ERp57-Calnexin Complex Formation.2021

    • Author(s)
      Tanikawa Y,# Kanemura S,# Ito D, Lin Y, Matsusaki M, Kuroki K, Yamaguchi H, Maenaka K, Lee YH, Inaba K, and *Okumura M.
    • Journal Title

      Molecules

      Volume: 26 Issue: 10 Pages: 2853-2853

    • DOI

      10.3390/molecules26102853

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K06520, KAKENHI-PROJECT-19K16092, KAKENHI-PROJECT-20K15969, KAKENHI-PUBLICLY-20H04688, KAKENHI-PLANNED-21H05095, KAKENHI-PROJECT-21H04758, KAKENHI-PLANNED-21H05253
  • [Journal Article] PDI Family Members as Guides for Client Folding and Assembly2020

    • Author(s)
      Kanemura S., Matsusaki M., Inaba K. and Okumura M.
    • Journal Title

      Int. J. Mol. Sci.

      Volume: 21 Issue: 24 Pages: 9351-9351

    • DOI

      10.3390/ijms21249351

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K16092, KAKENHI-PROJECT-20K15969, KAKENHI-PROJECT-18H03978, KAKENHI-PROJECT-19J00893
  • [Journal Article] 小胞体内におけるMHCの品質管理2020

    • Author(s)
      金村 進吾 , 松崎 元紀 , 前仲 勝実 , 稲葉 謙次 , 奥村 正樹
    • Journal Title

      臨床免疫・ ア レ ル ギ ー 科

      Volume: 74 Pages: 419-426

    • Data Source
      KAKENHI-PROJECT-19J00893
  • [Journal Article] 小胞体におけるMHCの品質管理2020

    • Author(s)
      金村 進吾 , 松崎 元紀 , 前仲 勝実 , 稲葉 謙次 , 奥村 正樹
    • Journal Title

      臨床免疫・アレルギー科

      Volume: 74 Pages: 419-426

    • Data Source
      KAKENHI-PROJECT-20K15969
  • [Journal Article] Regulation of plant ER oxidoreductin 1 (ERO1) activity for efficient oxidative protein folding2019

    • Author(s)
      Matsusaki Motonori、Okuda Aya、Matsuo Koichi、Gekko Kunihiko、Masuda Taro、Naruo Yurika、Hirose Akiho、Kono Keiichi、Tsuchi Yuichiro、Urade Reiko
    • Journal Title

      Journal of Biological Chemistry

      Volume: 294 Issue: 49 Pages: 18820-18835

    • DOI

      10.1074/jbc.ra119.010917

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K06587, KAKENHI-PROJECT-19J00893
  • [Journal Article] Protein Disulfide Isomerase family: from Proteostasis to Pathogenesis2019

    • Author(s)
      Matsusaki M.#, Kanemura S.#, Kinoshita M.#, Lee Y.H., Inaba K.*, and Okumura M.* (#equal contribution *corresponding authors)
    • Journal Title

      Biochim Biophys Acta-general subjects

      Volume: in press Issue: 2 Pages: 30080-30087

    • DOI

      10.1016/j.bbagen.2019.04.003

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-17H05868, KAKENHI-PROJECT-18H03978, KAKENHI-PROJECT-17H06521, KAKENHI-PROJECT-17K15098, KAKENHI-PROJECT-19K06520, KAKENHI-PROJECT-19K16092, KAKENHI-PROJECT-19J00893
  • [Presentation] 小胞体ストレスセンサーIRE1による活性酸素種の直接的感知と分子シャペロンによるその制御2024

    • Author(s)
      松崎元紀、金村進吾、齋尾智英、稲葉謙次、奥村正樹
    • Organizer
      日本農芸化学会2024度大会
    • Data Source
      KAKENHI-PROJECT-23KK0105
  • [Presentation] Elucidating the enzymatic reductive unfolding mechanism of spike/envelope proteins to guide anti-virus activities2023

    • Author(s)
      Shingo Kanemura, Rina Hashimoto, Motonori Matsusaki, Takuya Mabuchi, Mai Watabe, Tomohide Saio, Kazuo Takayama, Young-Ho Lee, Masaki Okumura
    • Organizer
      第23回日本蛋白質科学会年会 ★若手賞受賞講演
    • Invited
    • Data Source
      KAKENHI-PROJECT-23KK0105
  • [Presentation] 多量体分析で解き明かす小胞体ストレスセンサーが細胞応答を量的に調節する仕組み2023

    • Author(s)
      松崎元紀、奥村正樹
    • Organizer
      第46回日本分子生物学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-23KK0105
  • [Presentation] 小胞体ストレスセンサーIRE1の多量体形成ポテンシャルとストレス感知2023

    • Author(s)
      松崎元紀、横山武司、次田篤史、金村進吾、田尻道子、明石知子、野井健太郎、齋尾智英、稲葉謙次、奥村正樹
    • Organizer
      第23回日本蛋白質科学会年会
    • Data Source
      KAKENHI-PROJECT-23KK0105
  • [Presentation] 小胞体ストレスセンサーIRE1 によるストレス感知と越膜シグナル変換の分子機構2023

    • Author(s)
      松崎元紀、横山武司、次田篤史、金村進吾、田尻道子、明石知子、野井健太郎、齋尾智英、稲葉謙次、奥村正樹
    • Organizer
      第96回日本生化学会
    • Data Source
      KAKENHI-PROJECT-23KK0105
  • [Presentation] 分子間ジスルフィド結合による小胞体ストレスセンサーIRE1の会合状態制御2021

    • Author(s)
      松崎元紀, 横山武司, 次田篤史, 金村進吾, 田尻道子, 明石知子, 稲葉謙次, 奥村正樹
    • Organizer
      第6回東北大学若手研究者アンサンブルワークショップ
    • Data Source
      KAKENHI-PROJECT-19J00893
  • [Presentation] 分子間ジスルフィド結合による小胞体ストレスセンサーIRE1の会合状態制御2021

    • Author(s)
      松崎元紀, 横山武司, 次田篤史, 金村進吾, 田尻道子, 明石知子, 稲葉謙次, 奥村正樹
    • Organizer
      第6回東北大学若手研究者アンサンブルワークショップ
    • Data Source
      KAKENHI-PROJECT-20K15969
  • [Presentation] ミスフォールドタンパク質およびジスルフィド結合依存的なIRE1の会合状態制御2021

    • Author(s)
      松崎元紀, 金村進吾, 田尻道子, 明石知子, 稲葉謙次, 奥村正樹
    • Organizer
      日本農芸化学会2021年度大会
    • Data Source
      KAKENHI-PROJECT-20K15969
  • [Presentation] ミスフォールドタンパク質およびジスルフィド結合依存的なIRE1の会合状態制御2021

    • Author(s)
      松崎元紀, 金村進吾, 田尻道子, 明石知子, 稲葉謙次, 奥村正樹
    • Organizer
      日本農芸化学会2021年度大会
    • Data Source
      KAKENHI-PROJECT-19J00893
  • [Presentation] Novel Insight into PDI Family-regulated IRE1 Activation/Inactivation2020

    • Author(s)
      Motonori Matsusaki, Shingo Kanemura, Kenji Inaba, Masaki Okumura
    • Organizer
      第20回日本蛋白質科学会年会
    • Data Source
      KAKENHI-PROJECT-19J00893
  • [Presentation] Novel Insight into PDI Family-regulated IRE1 Activation/Inactivation2020

    • Author(s)
      Motonori Matsusaki, Shingo Kanemura, Kenji Inaba, Masaki Okumura
    • Organizer
      第20回日本蛋白質科学会年会
    • Data Source
      KAKENHI-PROJECT-20K15969
  • [Presentation] PDI family酵素によるヒト由来ガレクチンの機能制御機構の解明2019

    • Author(s)
      金村進吾、黒井邦巧、松崎元紀、山口宏、中林孝和、稲葉謙次、奥村正樹
    • Organizer
      第92回日本生化学大会
    • Data Source
      KAKENHI-PROJECT-19J00893
  • [Presentation] 新規レドックス分子による酸化的フォールディングの促進と応用2019

    • Author(s)
      松崎元紀、岡田隼輔、荒井堅太、日高雄二、稲葉謙次、村岡貴博、奥村正樹
    • Organizer
      第19回日本蛋白質科学会年会
    • Data Source
      KAKENHI-PROJECT-19J00893
  • [Presentation] Newly developed thiol-disulfide exchange agent, guanidino-thiol2019

    • Author(s)
      M. Matsusaki, S. Okada, K. Arai, Y. Hidaka, K. Inaba, T. Muraoka, and M. Okumura.
    • Organizer
      the 14the ER and Redox Club meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19J00893
  • [Presentation] Coupling effects of thiol and urea-type groups for promotion of oxidative folding2019

    • Author(s)
      M. Matsusaki, S. Okada, K. Inaba, T. Muraoka, and M. Okumura.
    • Organizer
      International Symposium on Disordered Proteins, Protein Folding, and Disease-causing Aggregation
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19J00893
  • [Presentation] 新規レドックス分子のデザイン法確立と酸化的フォールディングへの応用2019

    • Author(s)
      松崎元紀、岡田隼輔、荒井堅太、日高雄二、稲葉謙次、村岡貴博、奥村正樹
    • Organizer
      第92回日本生化学大会
    • Data Source
      KAKENHI-PROJECT-19J00893
  • [Presentation] PDIファミリーによるβ2-microglubulinの品質管理機構の解明2019

    • Author(s)
      木下岬、金村進吾、松崎元紀、李映昊、稲葉謙次、奥村正樹
    • Organizer
      第92回日本生化学大会
    • Data Source
      KAKENHI-PROJECT-19J00893
  • 1.  齋尾 智英 (80740802)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  川越 聡一郎 (10980716)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  奥村 正樹 (50635810)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 9 results
  • 4.  横山 武司 (20719447)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 5.  村岡 貴博 (70509132)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  金村 進吾
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 7.  松尾 光一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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