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SHIRAHAMA Haruhisa
白濱 晴久
Connect your ORCID iD
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Researcher Number
00000802
Affiliation (based on the past Project Information)
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1995 – 1998: 関西学院大学, 理学部, 教授
1987 – 1993: Hokkaido University Fac.of Sci., 理学部, 教授
1986: 北海道大学, 理学部, 助教授
Review Section/Research Field
Principal Investigator
天然物有機化学
/
Bioorganic chemistry
Except Principal Investigator
天然物有機化学
/
広領域
/
Bioorganic chemistry
Keywords
Principal Investigator
アクロメリン酸 / ドクササコ / オオワライタケ / ジムノピリン / 神経毒 / 脱分極活性 / カイノイド / アクロメリン酸類縁体 / ギムノピリン / キノコ
…
More
/ 神経興奮性アミノ酸 / オリゴイソプレノイド / HMGA / キラルなβ-ラクトン / キラルHMGA半エステル / グルタメート受容体 / acromelic acid / 光エノル化 / 光ジ-ルズアルダ-反応 / 立体選択的ピロリジン成合法 / 立体選択的アリ-ル化 / ピロ-ルカルボン酸 / 毒物質 / 神経伝達機能 / ピロリジン‐2,3‐ジカルボン酸 / グルタメ-ト受容体 / カイネ-ト型受容体 / コンホメ-ション認識 / 立体配置制限 / カイノイドの立体化学 / アクロメリン酸生合成中間体 / ジテルペン / グラヤノトキシン / ビニグロール / ヨウ化サマリウム(II) / ケチルラジカル環化反応 / タキソ-ル / ヨウ化サマリュウム / ケチルラジカル / HMPAの溶媒効果 / 立体配置選択性 / (5+2)反応 / 立体選択的ピロリジン環形成 / ラジカル反応 / メトキシメチルアミド / タキソール / ケタール化 / フムレン / 水銀塩 / 環化反応 / チルシフェロールの合成 / 神経興奮作用 / アクロメリン酸誘導体 / 全合成 / チルシフェロール / チルシフェロール 23-アセタート / 5-エンーl-オールのシャープレス酸化 / SEM基の除去条件 / 神経毒の単離 / 神経突起伸展作用物質 / 細胞生長制御物質 / 発癌プロモーター / 卵割阻害活性物質 / 摂食阻害物質 / 他感作用物質 / 神経毒の合成 / 発癌プロモ-タ- / 発癌性物質 / Neurotoxins / Isolation of neurotoxins / Neurotrophic compounds / Cell grouth control factors / Carcinogenic promotors / Cell decision inhibitors / Antifeedant / Allelopasic substances / カイノイドC_4側鎖の立体配座 / 4-フェニル-3-デヒドロプロリン / カルボキシシクロプロピルグリシン / カルボキシシクロペンチルグリシン / 立体配座解析 / アクロメリン酸B / 光照射下のジールズアルダー反応 / ピロリジン環の効率的形成 / Acromelic acid / Glutamate receptor / Configuration of C_4 side chain in kainoids / 4-phenyl-3-dehydroproline / Carboxycyclopropylglycine / Carboxycyclopentylglycine / Conformational analysis / ピロリジン環形成反応 / ラジカルによるC-C結合形成 / ベンジルラジカル / トリフロロアセトフェノン / ヒカゲシビレタケ / kainoid / poisonous mushroom / conformation / depolarizing activity / gymnopilin / HMGA ester / HMGA beta-lactone / 神経伝達物質 / グルタメート応答増強 / 新ピリジン合成法アクロメリン酸の全合成 / アクロメリン酸(A)の合成の合成 / アクロメリン酸(B)の合成 / ピリジン環の新合成法 / α-ピリドンの新合成法 / neurotransmittance / potentiation of glutamate response / a new method of pyridine synthesis / ヘミピオシアニン / クロラフィン / フェナジン-1-カルボン酸 / 2-ノネニル-3-メチル-4-キノリノール / 2-ヘプテニル-3-メチル-4-キノリノール / 1-アセトキシ-2 / 4-ジオキシ-6-ゲラニルゲラニルベンゼン / P.セパシア / P.エルギノーサ / シウルスーグレビレイ / 2ー(0ーヒドロキシフェンル)ー4ーホルミルチアゾール / フェナジンー1ーカルボン酸 / ポリオキシ-ゲラニルゲラニルベンゼン / hemipyocyanine / chlororaphine / phenazine-1-carboxylic acid / 2-nonenyl-3-methyl-4-quinolinol / 2-heptenyl-3-methyl-4-quinolinol / 新カイノイド / カイノイドの新合成法 / 神経興奮性物質 / ハナイグチ / 過酸化脂質生成阻害物質 / 過酸化脂質生成阻害 / 担子菌 / 過酸化脂質生成阻害活性 / 神経興奮性アシノ酸 / グルタメ-ト / プラストキノン / 光ジールズアルダー反応 / Clito eybe acromeralga / New kainoid / New synthetic method of kainoids / neuroexcitatory substonces / Gymnopilus spectalilis / Gymnopolin / Suillus greevillei / Lipid peroxilation inhibitor
…
More
Except Principal Investigator
マストパラン / 神経ペプチド / PHIボンベシン / 脳ANF / モルヒネアナログ / アセチルコリン受容体 / グルタミン酸阻害 / アクロメリン酸 / Naチャネル / 生体作用物質 / テルペノイド / アルカロイド / イリドイド / ステロイド / ペプチド / 全合成 / 構造決定 / Biologically active substance / Structural determination / Total synthesis / Terpenoid / Alkaloid / Iridoid / Secosteroid / Peptide / 核酸検出法 / 非RI / 蛍光基質 / Detection of nucleic acid / Non-RI / Fluorescent substrate / テルペノイドジアルデヒド / 海産天然物 / シガテラ毒 / 捕食防御物質 / 発癌物質 / 抗腫瘍性物質 / DNA切断機構 / 複合糖質 / 海洋天然物質 / 神経興奮性物質 / ワラビ発癌物質 / DNA切断分子機構 / 抗腫瘍性天然物質 / 抗酸化性天然物質 / 膜透過 / Terpenoid Dialdehyde / Marine Natural Product / Carcinogenic Substance / DNA Cleavage Mechanism / Antitumor Compound / Defensive Substance / Glycolipid / グリシノエクレピンA / 生合成 / 生合成推定経路 / バイオリズム / 活性物質 / ポリプレノ-ル / パリトキシン / 分子内スタッキング / 酵素 / 就眠運動 / 生合成前駆体合成 / 花色素 / Glycinoeclepin A / Biosynthesis / Biogenetic Pathway / Biorhythm / Active Substance / Polyprenol / Palytoxin / Intramolecular Stacking
Less
Research Projects
(
23
results)
Co-Researchers
(
41
People)
Project Start Year (Newest)
Project Start Year (Oldest)
ヒト細胞に強く作用する化合物の合成
Principal Investigator
Principal Investigator
白濱 晴久
Project Period (FY)
1998
Research Category
Grant-in-Aid for Scientific Research on Priority Areas (A)
Research Institution
Kwansei Gakuin University
タキソ-ルの全合成
Principal Investigator
Principal Investigator
白濱 晴久
Project Period (FY)
1997
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Kwansei Gakuin University
神経系に作用するキノコ毒の不斉合成
Principal Investigator
Principal Investigator
白濱 晴久
Project Period (FY)
1995
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Kwansei Gakuin University
Structure Determination, Synthesis and Biological Activity of Neuroactive Compounds
Principal Investigator
Principal Investigator
SHIRAHAMA Haruhisa
Project Period (FY)
1995 – 1997
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Bioorganic chemistry
Research Institution
Kwansei Gakuin University
生理活性ジテルペン類の高効率的キラル合成
Principal Investigator
Principal Investigator
白濱 晴久
Project Period (FY)
1993
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Hokkaido University
COMPREHENSIVE RESEARCH TOWARD THE ELUCIDATION OF BIOLOGICAL ACTIVITIES OF NATURAL ORGANIC COMPOUNDS
Principal Investigator
ISOE Sachihiko
Project Period (FY)
1993 – 1994
Research Category
Grant-in-Aid for Co-operative Research (A)
Research Field
Bioorganic chemistry
Research Institution
OSAKA CITY UNIVERSITY
担子菌より得られる生体内特異反応物質の構造解析、合成と機能発現
Principal Investigator
Principal Investigator
白濱 晴久
Project Period (FY)
1992
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Hokkaido University
DEVELOPMENT OF POTENT ACTIVE COMPOUNDS WORKING ON NEUROTRANSMIT ORGAN
Principal Investigator
Principal Investigator
SHIRAHAMA Haruhisa
Project Period (FY)
1992 – 1993
Research Category
Grant-in-Aid for Developmental Scientific Research (B)
Research Field
天然物有機化学
Research Institution
Hokkaido University
神経伝達機能をもつアミノ酸の合成と生体内作用
Principal Investigator
Principal Investigator
白濱 晴久
Project Period (FY)
1991
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Hokkaido University
担子菌より得られる生体内特異反応物質の構造解析、合成と機能発現
Principal Investigator
Principal Investigator
白濱 晴久
Project Period (FY)
1991
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Hokkaido University
ORGANIC CHEMISTRY OF THE BIOSYSTEM CONTROL SUBSTANCES
Principal Investigator
Principal Investigator
SHIRAHAMA Haruhisa
Project Period (FY)
1991 – 1992
Research Category
Grant-in-Aid for Co-operative Research (A)
Research Field
天然物有機化学
Research Institution
HOKKAIDO UNIVERSITY,(FACULTY OF SCIENCE)
神経伝達機能をもつアミノ酸の合成と生体内作用
Principal Investigator
Principal Investigator
白濱 晴久
Project Period (FY)
1990
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Hokkaido University
担子菌より得られる生体内特異反応物質の構造解析、合成と機能発現
Principal Investigator
Principal Investigator
白濱 晴久
Project Period (FY)
1990
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Hokkaido University
A novel fluorescent method for detection of subpicogram quantities of nucleic acids
Principal Investigator
HORI Hiroshi
Project Period (FY)
1990 – 1991
Research Category
Grant-in-Aid for Developmental Scientific Research (B)
Research Field
広領域
Research Institution
Hokkaido University
Multilateral Studies on Biologically Active Natural Substances
Principal Investigator
UDA Hisashi
Project Period (FY)
1989 – 1990
Research Category
Grant-in-Aid for Co-operative Research (A)
Research Field
天然物有機化学
Research Institution
Tohoku University
神経伝達物質の化学的研究
Principal Investigator
中嶋 暉躬
Project Period (FY)
1988
Research Category
Grant-in-Aid for Special Project Research
Research Institution
The University of Tokyo
Studies on Biosynthetic Mechanisms of Biologically Active Subsatnces and Their Applications
Principal Investigator
MURAI Akio
Project Period (FY)
1988 – 1990
Research Category
Grant-in-Aid for Co-operative Research (A)
Research Field
天然物有機化学
Research Institution
Hokkaido University
Isolation, Structural Determination and Synthesis of Biologically Active Substances Produced by Fungi
Principal Investigator
Principal Investigator
SHIRAHAMA Haruhisa
Project Period (FY)
1988 – 1990
Research Category
Grant-in-Aid for General Scientific Research (A)
Research Field
天然物有機化学
Research Institution
Hokkaido University
新カイノイドの化学合成による伝達物質と受容体との関係解明
Principal Investigator
Principal Investigator
白浜 晴久
Project Period (FY)
1987
Research Category
Grant-in-Aid for Special Project Research
Research Institution
Hokkaido University
有機水銀化合物の特性を利用する炭素環および複素環天然物の合成
Principal Investigator
Principal Investigator
白浜 晴久
Project Period (FY)
1987
Research Category
Grant-in-Aid for Special Project Research
Research Institution
Hokkaido University
Studies on the inhibitors from plant pathogens produced by soil germs
Principal Investigator
Principal Investigator
SHIRAHAMA Haruhisa, 白浜 晴久
Project Period (FY)
1987 – 1988
Research Category
Grant-in-Aid for Developmental Scientific Research
Research Field
天然物有機化学
Research Institution
Hokkaido University
有機水銀化合物の特性を利用する炭素環および複素環天然物の合成
Principal Investigator
Principal Investigator
白浜 晴久
Project Period (FY)
1986
Research Category
Grant-in-Aid for Special Project Research
Research Institution
Hokkaido University
Synthesis of accromelic acids and their derivatives
Principal Investigator
Principal Investigator
SHIRAHAMA Haruhisa
Project Period (FY)
1986 – 1987
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
天然物有機化学
Research Institution
Hokkaido University
# of Projects (Dsc)
# of Projects (Asc)
1.
TOKOROYAMA Takashi
(90046938)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
2.
HIRAMA Masahiro
(30165203)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
3.
MATSUDA Fuyuhiko
(10219446)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
4.
SHINOZAKI Haruhiko
(20109945)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
5.
YANAGIYA Mitsutoshi
(20000846)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
6.
YAMADA Kiyoyuki
(90022540)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
7.
KAKISAWA Hiroshi
(50015492)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
8.
KUSUMOTO Syouichi
(30028253)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
9.
ISOBE Minoru
(00023466)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
10.
YAMAMURA Syosuke
(40076708)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
11.
TACHIBANA Kazuo
(70142081)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
12.
MURAI Akio
(20000838)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
13.
SUGA Takayuki
(00033811)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
14.
松本 毅
(00000711)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
15.
中嶋 暉躬
(50012597)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
16.
宗像 英輔
(60072766)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
17.
山中 宏
(40004551)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
18.
矢内原 昇
(80046250)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
19.
井村 裕夫
(10025570)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
20.
UDA Hisashi
(40006292)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
21.
HORI Hiroshi
(40000814)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
22.
YOSHIDA Kiyohito
(40210687)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
23.
YOSHIDA Michihiro
(60001765)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
24.
高木 信夫
(20001852)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
25.
OHFUNE Yasufumi
(20142078)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
26.
ISOE Sachihiko
(90046946)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
27.
楠見 武徳
(70015882)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
28.
越智 雅光
(40036562)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
29.
中山 充
(20033821)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
30.
林 雄二
(40046917)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
31.
児玉 三明
(30004378)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
32.
上江田 捷博
(10145550)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
33.
上村 大輔
(00022731)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
34.
奥村 保明
(20021933)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
35.
加藤 忠弘
(20004319)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
36.
加藤 紀元
(00006305)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
37.
SHIZURI Yoshikazu
(90135294)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
38.
SANKAWA Ushio
(60012613)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
39.
OGURA Kyozo
(80006303)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
40.
丹羽 治樹
(20135297)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
41.
高杉 光雄
(70000833)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
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