YOSHIDA Michihiro 吉田廸弘

… Alternative Names

Researcher Number	60001765
Affiliation *help	1990 – 1997 : Hokkaido Univ. Faculty of Sch. Professor, 理学部, 教授 1992 : 北海道大学, 理学部動物染色体研究施設, 教授 1992 : 北道海大学, 医学部, 教授 1990 : 北海道大学, 理学部・染色体研, 教授 1986 – 1989 : 北海道大学, 理学部, 助教授 1987 – 1989 : 北海道大学, 理学部・動物染色体研究施設, 助教授 1986 : 北海道大学, 理学部動物染色体研究施設, 助教授
Review Section/Research Field	Principal Investigator Human genetics / 遺伝学 Except Principal Investigator Orthopaedic surgery / 広領域 / Laboratory animal science / Experimental pathology
Keywords	Principal Investigator FISH / がん遺伝子 / LECラット / ウイルソン病 / がん特異的染色体異常 / マッピング / がん遺伝子発現 / SCE / 肝癌 / 進銕 … More Except Principal Investigator がん遺伝子 / 染色体マッピング / 移植腫瘍 / 癌遺伝子 / 肝炎 / 突然変異 / 遺伝情報 / 銅代謝異常 / 発癌 / がん抑制遺伝子 / 肝癌 / LECラット / 活性酸素 / 化学発がん物質 / 研究資材 / モノクローナル抗体 / トランスジェニックマウス / 常染色体劣性遺伝 / ラット / 骨軟部悪性腫瘍 / 遺伝子再配列 / DNA修復 / ペプチド合成 / 白血病 / 化学発癌物質 / 単クロ-ン抗体 / メタロチオネイン / 色素性乾皮症 / RFLPs / HAM / 発癌遺伝子 / コホ-ト集団 / 成人性T細胞白血病 / neurotropism / 特異的染色体転座 / 染色体再構成 / コホート集団 / in situ hybridization / CGH / Rat Genome / T細胞受容体遺伝子再配列 / Gene rearrangement / 染色体異常 / 単クローン抗体 / 動物モデル / RT-PCR / 情報サービス / ウイルソン病 / セルロプラスミン / HTLVーI / Oncogene / ジェノミックライブラリ- / ユーイング肉腫 / D-penicillamine / 筋肉蛋白遺伝子 / LABORAATORY ANIMALS / Neurotropism / 非RI / 染色体 / ラット同種抗原国際ワークショップ / HIVーtatIII遺伝子 / Animal model / 腎癌 / Non-RI / Bone and soft tissue tumors / 系統差 / 微生物クリーニング / Ceruloplasmin / Breakpoint / ハイブリドーマ / 染色体転座 / ケラチン遺伝子 / SPECIES DIFFERENCES / Reference strain / 分子細胞遺伝学 / トランスフェクションアッセイ / N-ras / cーfos / 網膜芽細胞腫 / specific chromosome translocation / GENETIC HOMOLOGY / 国際実験動物会議(ICLAS) / Liver cirrhosis / Polymelase chain reaction / 核移植細胞 / Tumor Suppressor Genes / 遺伝的相同性 / 肝硬変 / 遺伝子増幅 / Synovial sarcoma / ANIMAL SCALE UP / ヒトゲノム / Internet / Cytokeratin gene / 核酸検出法 / pXーI遺伝子 / EXTRAPOLATION / 品質検査(モニタリング) / 微小核融合 / データベース / PCR monitoring / ヒト肝がんモデル動物 / Fluorescent substrate / French-Japanese Collaborative Program in Cancer Research / ラット系統 / リンフォカイン / German-Japanese Collaborative Program in Cancer Research / アニマルスケールアップ / HIV-1 tatIII / リンパ腫 / ユ-イング肉腫 / hts / DNA Repair / STRAIN DIFFERENCES / 滑膜肉腫 / がん細胞 / 酸化的DNA損傷 / Signal Transduction / gene rearrangement / Nomenclature Committee / HTLVー / 凍結保存 / 国際命名規約 / がん抑制遣伝子 / 腫瘍抗原 / キメラ遺伝子cDNA / 遺伝性腫瘍 / ヒト成人性T細胞白血病 / immunohistochemistry / Embryo bank / 神経芽細胞腫 / ウィルソン病 / 細胞周期チェックポイント調節因子 / 染色体外環状DNA / Ewing's sarcoma / Fulminant hepatitis / HTLVーII / インターネット / Immunogenetics / mRNA / 細胞工学方法 / 上皮性格 / Lymphokine / Oncogenes / ゲノム不安定性 / 国際ラット命名規約委員会 / 2国間共同研究 / HTLVーI taxー1遺伝子 / 発がんプロモーター / ウイルス発がん / エンブリオバンク / 可移植性腫瘍 / Tumor Supressor Gene / がん遣伝子 / ウイルムス腫瘍 / 外挿 / 膜酵素 / 動物実験 / 遺伝子プローグ / antisense DNA / ras遺伝子 / ATL / 類上皮肉腫 / DNAートランスフェクション / p53遺伝子 / RNA-PCR / pXーII遺伝子 / Tumor Antigen / 多重遺伝子変異 / ジーンバンク / 人小細胞肺癌 / PCRモニタリング / PHARMACOKINETICS / 薬物代謝能 / Tumor Promoter / 薬物代謝 / chimeric gene cDNA / ビタミンE / 国際基準系統 / Cleaning / T Cell Growth / Tumor specific chromo-some translocation / 遺伝子変異 / 遺伝子地図 / Transplantation / 実験動物 / シグナル伝達 / T細胞の増殖 / 皮膚がん / 高発がん遺伝子 / 切断点 / ペニシラミン / LEC / 癌関連遺伝子 / vーmos / Epithelioid tumor / 腫瘍特異的染色体転座 / P53遺伝子 / Wilson's disease / Cancer Metastasis / 蛍光基質 / transfection assay / 腫瘍遺伝子 / Viral Oncogene / 動物種差 / Immune Desponse / LEC rats / Epithelial characters / 癌抑制遺伝子 / Eker / 遺伝的品質検査 / Hepatoma / 細胞株 / Rhabdomyosarcoma / 肝臓薬物代謝酵素 / ヘテロ接合性の消失 / 紫外線 / Molecular cytogenetics / malignant bone and soft tissue tumors / 遺伝要因 / 発がんプロモ-タ- / Chromosome translocation / 免疫応答 / HTLV-1 tax-1 / 造腫瘍性検索 / テラトカルシノーマ / 肝がん / 遺伝子 / 劇症肝炎 / Nras / 遺伝子相同性 / 国際標準化 / アンチセンスDNA / TNF / 遺伝子性腫瘍 / International Exchange Program / Genomic instability / In situ hybridization / 修復 / ラット国際命名規約委員会 / 動物脳シナプス膜脂質 / がん転移 / 薬物代謝酵素 / 横紋筋肉腫 / Detection of nucleic acid / Bone and soft tissue malignancies / Abnormal copper metabolism / GENE / 疾患遺伝子 Less

Research Projects
(46results)
Co-Researchers
(145People)

ラット実験腫瘍の染色体遺伝子背景についての研究Principal Investigator
- Principal Investigator
  
  吉田廸弘
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Hokkaido University
銅代謝異常を伴うLECラット肝発がんの分子機構の解明
- Principal Investigator
  
  森道夫
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Sapporo Medical University
Molecular Analysis of the Expression Mechanism of Rearranged Genes Generated by Specific Chromosome Translocations in Malignant Bone and Soft Tissue Tumors
- Principal Investigator
  
  ABE Syuiti
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  HOKKAIDO NUIVERSITY
銅代謝異常を伴うLECラット肝発癌の分子機構の解明Principal Investigator
- Principal Investigator
  
  吉田廸弘
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Hokkaido University
ラット実験腫瘍の染色体遺伝子背景についての研究
- Principal Investigator
  
  杉山武敏
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
Joint study on the standardization of laboratory rats
- Principal Investigator
  
  KATOH Hideki
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Central Institute for Experimental Animals
銅代謝異常を伴うLECラット肝癌発生の分子機構の解明
- Principal Investigator
  
  武市紀年
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Hokkaido University
がん研究に要する研究資材開発
- Principal Investigator
  
  黒木登志夫
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokyo
ラット実験腫瘍の染色体遺伝子背景についての研究
- Principal Investigator
  
  杉山武敏
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyoto University
多段階発がんを促進する遺伝要因の作用機構
- Principal Investigator
  
  武部啓
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyoto University
Molecular Cytogenetic Studies on Epithelial Differentiation and Gene Rearrangement in Bone and Soft Tissue Tumors
- Principal Investigator
  
  ABE Syuiti
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Hokkaido University
肝炎・肝癌自然発症LECラットを用いた肝癌の発生と進展に関する分子病理学的研究
- Principal Investigator
  
  武市紀年
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Hokkaido University
がん研究に要する研究資材開発
- Principal Investigator
  
  黒木登志夫
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokyo
多段階発がん過程を促進する遺伝的要因の作用機構
- Principal Investigator
  
  武部啓
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyoto University
多段階発がん過程を促進する遺伝的要因の作用機構
- Principal Investigator
  
  武部啓
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
A COMPREHENSIVE RESEARCH FOR EXTRAPOLATION--GENETIC HOMOLOGY BETWEEN HUMAN BEINGS AND LABORATORY ANIMALS
- Principal Investigator
  
  KASAI Noriyuki
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  Laboratory animal science
- Research Institution
  TOHOKU UNIVERSITY
  Hokkaido University
Development of an imaging system for genome mappingPrincipal Investigator
- Principal Investigator
  
  YOSHIDA Michihiro
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Human genetics
- Research Institution
  HOKKAIDO UNIVERSITY
肝炎・肝癌自然発症LECラットを用いた肝癌の発生と進展に関する分子病理学的研究
- Principal Investigator
  
  武市紀年
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Hokkaido University
がん研究に要する研究資材開発
- Principal Investigator
  
  黒木登志夫
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokyo
非アイソト-プ標識in situ分子雑種法による遺伝子マッピング法の開発Principal Investigator
- Principal Investigator
  
  吉田廸弘
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  遺伝学
- Research Institution
  Hokkaido University
Cooperation and information exchange with European countries.
- Principal Investigator
  
  KUROKI Toshio
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  University of Tokyo
Genetic approach to Wilson disease by use of the hereditary hepatitis LEC ratsPrincipal Investigator
- Principal Investigator
  
  YOSHIDA Michihiro
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Human genetics
- Research Institution
  HOKKAIDO UNIVERSITY
肝炎・肝癌自然発症動物(LEC)を用いた肝癌の発生と進展に関する分子病理学的研究
- Principal Investigator
  
  TAKEICH Noritoshi
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Hokkaido University
がん研究に要する研究資材開発
- Principal Investigator
  
  黒木登志夫
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokyo
HTLVーIのneurotropismに関する研究(特にATLとHAMの病理組織をもちいたin situ hybridizationによるvirusの検索)
- Principal Investigator
  
  納光弘
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kagoshima University
HTLV-Iのneurotropismに関する研究(特にATLとHAMの病態組織をもちいたin situ liybridization によるvirusの検索)
- Principal Investigator
  
  納光弘
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kagoshima University
Molecular cytogenetic studies on tumorigenic genetic changes in bone and soft tissue malignancies
- Principal Investigator
  
  ABE Syuiti
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Hokkaido University
A novel fluorescent method for detection of subpicogram quantities of nucleic acids
- Principal Investigator
  
  HORI Hiroshi
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  広領域
- Research Institution
  Hokkaido University
がん研究に要する研究資材開発
- Principal Investigator
  
  小高健
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokyo
発癌遺伝子移入による正常造血系細胞のimmortalization
- Principal Investigator
  
  関口豊三
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kohno Clinical Medicine Research Institute
Immunogenetical and Immunopathological Studies of Mechanisms of Fulminant Hepatitis in LEC Rats with Spontaneous Hepatits
- Principal Investigator
  
  TAKEICH Noritoshi
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Hokkaido University
がん研究に要する研究資材開発
- Principal Investigator
  
  小高健
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokyo
発がんにおける突然変異と染色体再構成
- Principal Investigator
  
  佐々木正夫
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyoto University
発癌遺伝子移入による正常造血系細胞のimmortalzation
- Principal Investigator
  
  関口豊三
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kohno Clinical Medicine Research Institute
がん遺伝子および関連遺伝子の染色体マッピングPrincipal Investigator
- Principal Investigator
  
  吉田廸弘
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Hokkaido University
Information Exchange on Cancer Research with North American Countries
- Principal Investigator
  
  YAMAGUCHI Nobuo, 河井貞明
- Project Period (FY)
  1988 – 1990
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  The Institute of Medical Science, The University of Tokyo
がん研究に要する研究資材開発
- Principal Investigator
  
  小高健
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokyo
発がんにおける突然変異と染色体再構成
- Principal Investigator
  
  佐々木正夫
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyoto University
発癌遺伝子の移入による正常造血系細胞のImmortalizationと癌化
- Principal Investigator
  
  関口豊三
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
がん遺伝子および関連遺伝子の染色体マッピングPrincipal Investigator
- Principal Investigator
  
  吉田廸弘
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Hokkaido University
ヨーロッパなどがん研究先進国との研究交流
- Principal Investigator
  
  豊島久真男
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Overseas Scientific Research
- Research Institution
  The University of Tokyo
がん研究に要する研究資材開発
- Principal Investigator
  
  小高健
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokyo
発がんにおける突然変異と染色体再構成
- Principal Investigator
  
  佐々木正夫
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyoto University
細胞工学方法によるテラトカルシノーマの分化誘導と腫瘍遺伝子発現の制御
- Principal Investigator
  
  関口豊三
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
がん遺伝子および関連遺伝子の染色体マッピングPrincipal Investigator
- Principal Investigator
  
  吉田廸弘
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Hokkaido University
Suppression of chromosome aberrations in chromosome aberration syndromes by microcell mediated chromosome transferPrincipal Investigator
- Principal Investigator
  
  YOSHIDA Michihiro C.
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Human genetics
- Research Institution
  Hokkaido University

1. ABE Syuiti (80125278)

# of Collaborated Projects : 10results

# of Collaborated Products : 0results
2. 豊島久真男 (90029760)

# of Collaborated Projects : 9results

# of Collaborated Products : 0results
3. KUROKI Toshio (90006073)

# of Collaborated Projects : 8results

# of Collaborated Products : 0results
4. 橋本嘉幸 (90072412)

# of Collaborated Projects : 8results

# of Collaborated Products : 0results
5. 森道夫 (00045288)

# of Collaborated Projects : 6results

# of Collaborated Products : 0results
6. TAKEICH Noritoshi (40002133)

# of Collaborated Projects : 5results

# of Collaborated Products : 0results
7. SHIBUYA Masabumi (10107427)

# of Collaborated Projects : 5results

# of Collaborated Products : 0results
8. 杉山俊博 (00127242)

# of Collaborated Projects : 5results

# of Collaborated Products : 0results
9. 青木國雄 (60073102)

# of Collaborated Projects : 4results

# of Collaborated Products : 0results
10. 小高健 (00012691)

# of Collaborated Projects : 4results

# of Collaborated Products : 0results
11. 関口豊三 (70076975)

# of Collaborated Projects : 4results

# of Collaborated Products : 0results
12. 岩倉洋一郎 (10089120)

# of Collaborated Projects : 4results

# of Collaborated Products : 0results
13. 長尾美奈子 (40100151)

# of Collaborated Projects : 4results

# of Collaborated Products : 0results
14. 松本耕三 (00002246)

# of Collaborated Projects : 4results

# of Collaborated Products : 0results
15. 高木信夫 (20001852)

# of Collaborated Projects : 4results

# of Collaborated Products : 0results
16. 丸野内棣 (90181825)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
17. 松島泰次郎 (10012759)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
18. NOJIMA Takayuki (50142732)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
19. 山岸秀夫 (90025429)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
20. 武部啓 (10028318)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
21. 錦織千佳子 (50198454)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
22. 野村大成 (90089871)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
23. 立花章 (20188262)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
24. 山泉克 (70107093)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
25. 杉山武敏 (20030851)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
26. 前田盛 (50030911)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
27. 志佐湍 (90073121)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
28. 樋野興夫 (90127910)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
29. 佐々木正夫 (20013857)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
30. 神田尚俊 (40075429)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
31. 福原資郎 (40142301)

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YOSHIDA Michihiro 吉田 廸弘

吉田 迪弘 ヨシダ ミチヒロ

Research Projects

Co-Researchers

ラット実験腫瘍の染色体遺伝子背景についての研究Principal Investigator

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銅代謝異常を伴うLECラット肝発癌の分子機構の解明Principal Investigator

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Development of an imaging system for genome mappingPrincipal Investigator

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YOSHIDA Michihiro 吉田廸弘

吉田迪弘ヨシダミチヒロ