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HIRANO Toshio  平野 俊夫

ORCIDConnect your ORCID iD *help
Researcher Number 40136718
Other IDs
Affiliation (based on the past Project Information) *help 2013 – 2014: 大阪大学, その他部局等, 学長
2012: 大阪大学, その他部局等, 総長
2002 – 2010: Osaka University, Graduate School of Frontier Biosciences, Professor, 生命機能研究科, 教授
2003: 阪大, 教授
1999 – 2001: 大阪大学, 医学系研究科, 教授 … More
1999: Osaka University, Graduate School of Medicine, Biomedical Research Center, Professor, 医学部, 教授
1989 – 1997: 大阪大学, 医学部, 教授
1993: 大阪大学 医学部附属バイオメディカル教育センター, 教授
1992: 大阪大学, 医学部附属バイオメディカル教育センター, 教授
1992: 阪大, 医・バイオセ, 教授
1991: 大阪大学, 医学部・バイオメディカル教育センター(免疫学), 教授
1988: Associate Professor, Inst. Molec. & Cell. Biology, Osaka University, 細胞工学センター, 助教授
1987: 大阪大学, 細胞工学センター, 助手
1986: 大阪大学, 細胞工学センター, 助教授 Less
Review Section/Research Field
Principal Investigator
Immunology / Biological Sciences / Immunology / Biological Sciences / Experimental pathology
Except Principal Investigator
Immunology / Biological Sciences / Cell biology
Keywords
Principal Investigator
シグナル伝達 / サイトカイン / 自己免疫疾患 / cytokine / signal transduction / IL-6 / 遺伝子発現 / BST-1 / 慢性関節リウマチ / インターロイキン6 … More / 多発性骨髄腫 / inflammation / antigen receptor / 骨髄ストローマ / 抗原受容体 / rheumatoid arthritis / 免疫反応 / STAT3 / 亜鉛 / 接着因子 / 受容体 / junB / インタ-ロイキン6 / トランスジェニックマウス / インタ-ロイキン / second messenger / intracellular signaling / Zinc / homeostatic proliferation of T cells / memory T cells / gp130 / T細胞 / 樹状細胞 / 細胞運動 / 免疫 / GP130 / T 細胞の恒常的な増殖 / メモリー T 細胞 / セカンドメッセンジャー / 細胞内信号 / T細胞の恒常的な増殖 / メモリーT細胞 / autoimmune disease / cell differentiation / co-receptor / immune response / ノックアウトマウス / 免疫異常 / 炎症疾患 / 細胞分化 / 補助受容体 / 免疫応答 / gene expression / bone marrow stromal cell / 炎症 / costimulatory factor / apoptosis / tolerance / lymphocyte lineage / クローナル除去 / リンパ球初期分化 / 補助因子受容体 / サイトカイン受容体 / 補助刺激因子 / 細胞死 / 免疫寛容 / リンパ球増殖分化 / receptor / autoimmune diseases / Interleukin 6 / ウイルス / B細胞初期分化 / 亜鉛恒常性 / 細胞内亜鉛信号 / カスペース / MTF1 / 炎症回路 / 亜鉛シグナル / Zip13 / 亜鉛トランスポーター / IRF / CIS / STAT / 自然免疫 / 免疫抑制 / アポトーシス / ケモカイン / ウィルス / ストローマ細胞 / プレB細胞増殖 / 転写因子 / Statファミリー / Jakキナーゼ / チロシンキナーゼ / JunB / ストロ-マ細胞 / 形質細胞腫 … More
Except Principal Investigator
サイトカイン / 情報伝達 / autoimmune disease / signal transduction / IL-6 / 免疫寛容 / 免疫制御 / レセプター / 分子生物学 / 造血因子 / 自己免疫病 / Fas / B70 / 自己免疫疾患 / NMR / シグナル伝達 / FcεRII / FcεRIIaとFcεRIIb / インターロイキン6 / 細胞死 / 転写因子 / IL-6応答領域 / gp130 / 免疫病 / EBV / 発現クロ-ニング / レセプタ- / コロニ-刺激因子 / インタ-ロイキン / エフェクター細胞 / サイトカインレセプター / Fcepsilon receptor (FcepsilonRII) / plasmacytoma growth factor / B cell stimulatory factor 2 (BSF2) / Interleukin 6 (IL-6) / Two colour FACS解析 / Bリンパ球増殖因子(BCGF) / 活性化Bリンパ球 / 抗ペプチド抗体Myxoma / 部分アミノ酸配列 / Bリンパ球分因子(BCDF) / Bリンパ球の増殖と分化 / アトピー / IFNβ2 / 抗体産生 / BSF2 / Fcrレセプター / 抗IL6抗体 / 肝細胞刺激因子 / BiF2 / IL-4 / IL-6レセプターcDNA / CD23 / Fcεレセプター / IL-6レセプター / ミエローマ増殖因子 / Bリンパ球分化因子 / regeneration, / autoimmune diseases / memory / recognition and diversity / thymus, bone marrow, lymph nodes / spatio-temporal regulation / immune surveillance / アレルギー / 感染症 / がん / 免疫系の修復と強化 / 免疫監視システム / 免疫組織の修復と強化 / ワクチン / 免疫シグナル / 認識の多様性 / 自然免疫 / 免疫監視機構 / 危険シグナル / 胸腺、骨髄、リンパ組織 / 再生、修復 / 免疫記憶 / 抗原認識、多様性 / 胸腺、骨髄・二次リンパ節 / 時空間的制御 / 免疫監視 / immune proteasome / NK cell / cytokine receptors / antigen receptors / collaborative research / molecular basis of immune disease / B,T細胞分化 / 免疫異常 / 免疫プロテアソーム / NK細胞 / サイトカイン受容体 / 抗原受容体 / 自己抗原病 / 共同研究 / 免疫病の分子基盤 / gene knockout mouse / transgenic mouse / international symposium / information exchanges / providing information / group of generalization / immune tolerance / immune regulation / 免疫応答 / ジーンノックアウトマウス / トランスジェニックマウス / 国際シンポジウム / 情報交換 / 情報提供 / 総括班 / antigenic peptide / MHC molecule / adhesion molecule / CD5^+B cells / apoptosis / self-tolerance / 抗原ペプチド / MHC分子 / 接着分子 / CD5^+B細胞 / アポプトーシス / 自己トレランス / Biosensor / Protein interaction / Gene targeting / Higher plants / Morphogenesis / Cre-loxP / Fission yeast / 植物 / 胚形成 / 蛋白高次機能構造 / 遺伝子ターゲティング / RNAプロセシング / バイオモニタリング / DNA再複製 / 細胞周期 / 温度感受性突然変異体 / ATPase / 免疫系 / バイオセンサー / 分子相互作用 / 遺伝子標的 / 高等植物 / 形態形成 / Cre-IoxP / 分裂酵母 / Cancer Metastasis / DNA Repair / Signal Transduction / Tumor Suppressor Genes / Oncogenes / German-Japanese Collaborative Program in Cancer Research / French-Japanese Collaborative Program in Cancer Research / International Exchange Program / がん抑制遣伝子 / がん遣伝子 / 2国間共同研究 / ヒトゲノム / DNA修復 / がん転移 / がん細胞 / がん抑制遺伝子 / がん遺伝子 / nuclear factor / receptor / interleukin 6 / cytokine / acute phase reactions / myeloma / NODマウス / NFーILー6 / ILー6トランスゲニックマウス / シグナルトランスデューサー(gp130) / ILー6レセプター / インターロイキン6(ILー6) / plasmacytoma / I型糖尿病 / ILー6トランスジェニックマウス / 急性期蛋白 / ILー6転写調節因子(NFーILー6) / シグナル伝達分子(gp130) / インタ-ロイキン6レセプタ-(ILー6R) / 自己β細胞特異Tリンパ球 / プラスマサイト-マ / NFーIL6β, / NFーIL6 / ILー6シグナル伝達分子(gp130) / ILー6レセプタ- / インタ-ロイキン6(ILー6) / NF-IL6 / ras / MAPカイネース / タイロシンカイネース / 信号伝達 / ミエローマ / 急性期反応 / 自己免疫 / セリンエステラーゼ / 慢性B白血病細胞 / NK骨髄腫細胞 / CTL / chordin / noggin / 中胚葉背側化 / 神経誘導 / Spemann organizer / 低分子量型G蛋白質 / 低分子暈型G蛋白質 / 核輸送 / bc1-2 / Fas因子 / 肝細胞増殖因子(HGF) / インターロイキン-6(IL-6) / カルデスモン / ETSファミリー / 細胞増殖分化 / junB / STAT3 / JAK / etsファミリー / Statファミリー / IL-6シグナル伝達 / Sak / チロシンキナーゼ / STAT / Jak / GTP結合蛋白質 / 脂質メディエーター / 細胞機能発現 / 生理活性分子 / 細胞接着分子 / 細胞内シグナル伝達 / 発現クローニング / コロニー刺激因子 / インターロイキン / 転写活性因子 / NFーkB / redox regulation / HTLVー1 / TRX / ウイルス疾患 / 慢性関節リウマチ / ATL / Thioredoxin / ADF / HAM / HTLV-I / 免疫細胞活性化 / ウィルス疾患 / チロシンリン酸化 / 抗レセプタ-抗体 / 異常増殖 / T細胞 / エフェクタ-細胞 / シグナル伝達機構 / サイトカイン レセプタ- / B白血病細胞 / 骨髄腫細胞 / T細胞抗原受容体 / ナチュラルキラー細胞 / 細胞傷害性T細胞 Less
  • Research Projects

    (37 results)
  • Research Products

    (215 results)
  • Co-Researchers

    (171 People)
  •  Characterization of intracellular Zn signaling and its relationship to diseasesPrincipal Investigator

    • Principal Investigator
      HIRANO Toshio
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Immunology
    • Research Institution
      Osaka University
  •  Activation of Zinc signal and its biological significancePrincipal Investigator

    • Principal Investigator
      HIRANO Toshio
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Immunology
    • Research Institution
      Osaka University
  •  サイトカインによる免疫応答制御機構とその異常Principal Investigator

    • Principal Investigator
      平野 俊夫
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Immunology
    • Research Institution
      Osaka University
  •  Regulation of Immune responses and autoimmune diseases by cytokinesPrincipal Investigator

    • Principal Investigator
      HIRANO Toshio
    • Project Period (FY)
      2003 – 2007
    • Research Category
      Grant-in-Aid for Specially Promoted Research
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  Immune Surveillance, Its cellular and molecular basis, regulation and maintenance

    • Principal Investigator
      WATANABE Takeshi
    • Project Period (FY)
      2003 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      RIKEN
      Kyushu University
  •  抗原非特異的分子による情報伝達制御Principal Investigator

    • Principal Investigator
      平野 俊夫
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  サイトカイン、接着分子の情報伝達制御Principal Investigator

    • Principal Investigator
      平野 俊夫
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  Regulatory mechanism of signal transduction in the immune system.Principal Investigator

    • Principal Investigator
      HIRANO Toshio
    • Project Period (FY)
      1999 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  Molecular basis for immunological disease

    • Principal Investigator
      WATANABE Takeshi
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Immunology
    • Research Institution
      KYUSHU UNIVERSITY
  •  マウス神経初期発生におけるnoggin,Shhのシグナル伝達の解明

    • Principal Investigator
      日比 正彦
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  シグナル伝達性転写因子群の活性化機序と癌化における役割

    • Principal Investigator
      中嶋 弘一
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  細胞の増殖・分化・死のシグナル伝達機構

    • Principal Investigator
      祖父江 憲治
    • Project Period (FY)
      1995 – 1999
    • Research Category
      Grant-in-Aid for COE Research
    • Research Institution
      Osaka University
  •  造血系構築とくにマクロファージ分化におけるIL-6シグナルの解析

    • Principal Investigator
      松田 正
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  シグナル伝達性転写因子郡の活性化機序と癌化における役割

    • Principal Investigator
      中島 弘一
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  Molecular mechanisms of chronic inflammaroty proliferative diseasePrincipal Investigator

    • Principal Investigator
      HIRANO Toshio
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Experimental pathology
    • Research Institution
      Osaka University
  •  IL-6による発癌機構の解析Principal Investigator

    • Principal Investigator
      平野 俊夫
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Osaka University
  •  サイトカインと細胞接着分子による細胞内シグナル伝達ネットワークの研究

    • Principal Investigator
      新井 賢一
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Cell biology
    • Research Institution
      The University of Tokyo
  •  自己免疫疾患の発症機序に関する分子生物学的研究Principal Investigator

    • Principal Investigator
      平野 俊夫
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Immunology
    • Research Institution
      Osaka University
  •  Regulation of Gene Expression

    • Principal Investigator
      TANIGUCHI Masaru
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Chiba University
  •  Studies on molecular mechanisms of autoimmune diseases

    • Principal Investigator
      KISHIMOTO Tadamitsu
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Osaka University
  •  Molecular mechnisms of immune tolerance.Principal Investigator

    • Principal Investigator
      HIRANO Toshio
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  Molecular mechanism of immune regulation and immune tolerance

    • Principal Investigator
      SASAZUKI Takehiko
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University
  •  IL-6による発癌機構の解析Principal Investigator

    • Principal Investigator
      平野 俊夫
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Osaka University
  •  造血因子の構造と作用の分子生物学的検討と生体内作用

    • Principal Investigator
      新井 賢一
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  免疫制御・寛容の分子機構

    • Principal Investigator
      SASAZUKI Takehiko
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Institution
      Kyushu University
  •  造血因子の構造と作用の分子生物学的検討と生体内作用

    • Principal Investigator
      新井 賢一
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  ウィルス疾患における免疫細胞活性化異常に関する総合研究

    • Principal Investigator
      淀井 淳司
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      Immunology
    • Research Institution
      Kyoto University
  •  Cooperation and information exchange with European countries.

    • Principal Investigator
      KUROKI Toshio
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      University of Tokyo
  •  エフェクタ-細胞の機能分化:サイトカインとそのレセプタ-系を中心にしたアプロ-チ

    • Principal Investigator
      高津 聖志
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kumamoto University
  •  形質細胞腫/骨髄腫発生機構におけるインタ-ロイキン6とその受容体発現異常の解析Principal Investigator

    • Principal Investigator
      平野 俊夫
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Osaka University
  •  造血因子の構造と作用の分子生物学的検討と生体内作用

    • Principal Investigator
      新井 賢一
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  ILー6による発癌機構の解析Principal Investigator

    • Principal Investigator
      平野 俊夫
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Osaka University
  •  Investigation of the molecular mechanisms of immunological disorders with abnormal expression of the interleukin 6 gene.Principal Investigator

    • Principal Investigator
      HIRANO Toshio
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Immunology
    • Research Institution
      Osaka University
  •  エフェクター細胞の機能分化;サイトカインとそのレセプター系を中心としたアプローチ

    • Principal Investigator
      TAKATSU Kiyoshi
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kumamoto University
  •  Studies on molecular regulation of the immune system

    • Principal Investigator
      KISHIMOTO Tadamitsu
    • Project Period (FY)
      1989 – 1992
    • Research Category
      Grant-in-Aid for Specially Promoted Research
    • Research Institution
      Osaka University
  •  エフェクター細胞の機能分化:サイトカインとそのレセプター系を中心にしたアプローチ

    • Principal Investigator
      高津 聖志
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kumamoto University
  •  Bリンパ球増殖・分化機構の解明とその異常制御に関する研究

    • Principal Investigator
      KISHIMOTO Tadamitsu
    • Project Period (FY)
      1985 – 1988
    • Research Category
      Grant-in-Aid for Specially Promoted Research
    • Research Institution
      Institute for Molecular and Cellular Biology, Osaka University

All 2015 2014 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation Book Patent

  • [Book] Interleukin 6 in autoimmune and inflammatory diseases.2010

    • Author(s)
      Toshio Hirano.
    • Publisher
      Proceedings of the Japan Academy(in press)
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Book] Grasp a pTyr-peptide by its SOCS.2006

    • Author(s)
      Hirano, T., M.Murakami.
    • Total Pages
      4
    • Publisher
      Dev. Cell
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Book] Interleukin -6 in Encyclopedia of Endocrinology and Endocrine Diseases2004

    • Author(s)
      Ohtani, T., T.Hirano.
    • Total Pages
      7
    • Publisher
      Academic Press
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Book] Interleukin -6 in Encyclopedia of Endocrinology and Endocrine diseas2004

    • Author(s)
      Ohtani, T., T. Hirano.
    • Total Pages
      7
    • Publisher
      Academic Press
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Book] T.New IL-6 (gp130) family cytokine members, CLC/NNT1/BSF3 and IL-27. Growth Facotrs2004

    • Author(s)
      Murakami, M., D.Kamimura, T.Hirano
    • Total Pages
      3
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Book] signal Transducers and Activators of Transcription (STATs) : Activatio and Biology2003

    • Author(s)
      Yamashita, S., Hirano, T.
    • Total Pages
      13
    • Publisher
      Kluwer Academic Publishers
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Book] Reviews of Physiology, Biochemistry and Pharmacology2003

    • Author(s)
      Kamimura, D., Ishihara, K., Hirano, T.
    • Total Pages
      38
    • Publisher
      Springer-Verlag
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Book] Signal Transducers and Activators of Transcription (STATs) : Activatio and Biology2003

    • Author(s)
      Kamimura, D., Hirano, T.
    • Total Pages
      21
    • Publisher
      Kluwer Academic Publishers
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Book] Encyclopedia of Hormones2003

    • Author(s)
      Kamimura, D., Hirano, T.
    • Total Pages
      10
    • Publisher
      Academic Press
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Journal Article] Temporal expression of growth factors triggered by epiregulin regulates inflammation development.2015

    • Author(s)
      Harada, M., Kamimura, D., Arima, Y., Kohsaka, H., Nakatsuji, Y., Nishida, M., Atsumi, T., Meng, J., Bando, H., Singh, R., Sabharwal, L., Jiang, J. J., Kumai, N., Miyasaka, N., Sakoda, S., Yamauchi-Takihara, K., Ogura, H., Hirano, T. & Murakami, M.
    • Journal Title

      J Immunol

      Volume: 194 Issue: 3 Pages: 1039-1046

    • DOI

      10.4049/jimmunol.1400562

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-14F04789, KAKENHI-PROJECT-24249028, KAKENHI-PROJECT-24390098, KAKENHI-PROJECT-24500854, KAKENHI-PROJECT-24590583, KAKENHI-PROJECT-24659221, KAKENHI-PROJECT-26460574, KAKENHI-PROJECT-15K01712
  • [Journal Article] Zinc-binding metallothioneins are key modulators of IL-4 production by basophils2015

    • Author(s)
      Ugajin T, Nishida K, Yamasaki S, Suzuki J, Mita M, Kubo M, Yokozeki H, Hirano T
    • Journal Title

      Mol Immunol

      Volume: 66 Issue: 2 Pages: 180-188

    • DOI

      10.1016/j.molimm.2015.03.002

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24249028, KAKENHI-PROJECT-24249058, KAKENHI-PUBLICLY-15H01162, KAKENHI-PUBLICLY-15H01267, KAKENHI-PROJECT-25461665
  • [Journal Article] Inflammation Amplifier, a New Paradigm in Cancer Biology2014

    • Author(s)
      Atsumi T, Singh R, et al.
    • Journal Title

      Cancer Research

      Volume: 74 Issue: 1 Pages: 8-14

    • DOI

      10.1158/0008-5472.can-13-2322

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J00819, KAKENHI-PROJECT-14F04789, KAKENHI-PROJECT-24249028, KAKENHI-PROJECT-24390098, KAKENHI-PROJECT-24790472, KAKENHI-PROJECT-26460574
  • [Journal Article] Revisiting the 1986 molecular cloning of interleukin 6.2014

    • Author(s)
      Hirano T
    • Journal Title

      Front Immunol.

      Volume: 5 Pages: 456-456

    • DOI

      10.3389/fimmu.2014.00456

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24249028
  • [Journal Article] IL-6と受容体系経路2012

    • Author(s)
      村上正晃、有馬康伸、平野俊夫
    • Journal Title

      日本臨床増刊号

      Volume: - Pages: 192-206

    • Data Source
      KAKENHI-PROJECT-24249028
  • [Journal Article] Local microbleeding facilitates IL-6- and IL-17-dependent arthritis in the absence of tissue antigen recognition by activated T cells.2011

    • Author(s)
      Murakami, M., D.Kamimura, T.Hirano, et al.
    • Journal Title

      J.Exp.Med.

      Volume: 208 Pages: 103-114

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Journal Article] Zinc in Allergy, Autoimmune, and Hard and Connective Tissue Diseases.2011

    • Author(s)
      Keigo NISHIDA, Toshiyuki FUKADA, Satoru YAMASAKI, Masaaki MURAKAMI, Toshio HIRANO
    • Journal Title

      Zinc in Human Health in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Journal Article] 題60回藤原セミナー「亜鉛シグナルと細胞機能」を開催して2011

    • Author(s)
      平野俊夫、村上正晃
    • Journal Title

      亜鉛栄養治療 1(2)

    • Data Source
      KAKENHI-PROJECT-20249030
  • [Journal Article] The Zinc Transporter SLC39A14/ZIP14 Controls G-Protein Coupled Receptor-Mediated Signaling Required for Systemic Growth.2011

    • Author(s)
      Hojyo S., T.Fukada, S.Shimoda, W.Ohashi, B-H.Bin, H.Koseki, T.Hirano
    • Journal Title

      PLoS ONE 6(3)

    • NAID

      10030756017

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Journal Article] Zinc homeostasis and signaling in health and diseases.2011

    • Author(s)
      Toshiyuki Fukada, Satoru Yamasaki, Keigo Nishida, Masaaki Murakami, Toshio Hirano
    • Journal Title

      Journal of Biological Inorganic Chemistry in press

    • Data Source
      KAKENHI-PROJECT-20249030
  • [Journal Article] サイトカインによる炎症と抗炎症制御「亜鉛による免疫制御-アレルギー応答における亜鉛/亜鉛トランスポーターの役割」2010

    • Author(s)
      西田圭吾、平野俊夫
    • Journal Title

      サイトカインによる免疫制御と疾患(実験医学増刊号(株)羊土社)第3章 28(12)

    • Data Source
      KAKENHI-PROJECT-20249030
  • [Journal Article] Interleukin 6 in autoimmune and inflammatory diseases.2010

    • Author(s)
      Toshio Hirano.
    • Journal Title

      Physical and Biological Sciences

      Volume: 86 Pages: 717-730

    • Data Source
      KAKENHI-PROJECT-20249030
  • [Journal Article] IL-6 positively regulates Foxp3+CD8+ T cells in vivo.2010

    • Author(s)
      Nakagawa T., T.Hirano, M.Murakami, et al.
    • Journal Title

      Int.Immunol.

      Volume: 22 Pages: 129-139

    • NAID

      10027391497

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Journal Article] Zinc suppresses Th17 development via inhibition of STAT3, activation.2010

    • Author(s)
      Kitabayashi C., M.Murakam, T.Hirano, et al.
    • Journal Title

      Int.Immunol.

      Volume: 22 Pages: 375-386

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Journal Article] SHP2 mediates gp130-dependent cardiomyocyte hypertrophy vianegative regulation of skeletal alpha-actin gene.2010

    • Author(s)
      Nakaoka, Y., T.Hirano, et al.
    • Journal Title

      J.Mol.Cell.Cardiol.

      Volume: 49 Pages: 157-164

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Journal Article] Zinc suppresses Thdevelopment via inhibition of STAT3 activation.2010

    • Author(s)
      Kitabayashi C., T.Fukada, M.Kanamoto, W.Ohashi, S.Hojyo, T.Atsumi, N.Ueda, I.Azuma, H.Hirota, M.Murakami, T.Hirano
    • Journal Title

      Int.Immunol. 22(5)

      Pages: 375-386

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Journal Article] Interleukin 6 in autoimmune and inflammatory diseases.2010

    • Author(s)
      平野俊夫
    • Journal Title

      Proceedings of the Japan Academy, Ser.B, Physical and Biological Sciences 86(7)

      Pages: 717-730

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Journal Article] IFN-γ expression in CD8+ T cells regulated by IL-6 signal is involved in superantigen-mediated CD4+ T cell death.2009

    • Author(s)
      *Atsuini, T. *M. Sato, T. Hirano, M. Murakami, et al. (*equal contribution)
    • Journal Title

      International Immunology 21

      Pages: 73-80

    • NAID

      10025383990

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Journal Article] Zinc transporter Znt5/Slc30a5 is required for the mast cell-mediated delayed-type allergic reaction but not the immediate-type reaction.2009

    • Author(s)
      Nishida K., A.Hasegawa, S.Nakae, K.Oboki, H.Saito, S.Yamasaki, T.Hirano
    • Journal Title

      J.Exp.Med. 206

      Pages: 1351-1364

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Journal Article] Y. Arima, H. Ogura, C. Kitabayashi, J. -J. Jiang, T. Fukushima, D. Kamimura, Hepatic IL-7 expression regulates T cell Responses.2009

    • Author(s)
      Sawa, Y., T. Hirano, M. Murakami, et al.
    • Journal Title

      Immunity (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Journal Article] Roles of Zinc and Zinc signaling in immunity : Zinc is an intracellular signaling molecule.2008

    • Author(s)
      Hirano, T.
    • Journal Title

      Adavanced Immunology (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Journal Article] 生体微量金属:恒常性維持・疾患との関係を紐解く「亜鉛の細胞内シグナル伝達における役割」2008

    • Author(s)
      村上正晃、平野俊夫
    • Journal Title

      細胞工学((株)秀潤社発行) 27(3)

      Pages: 237-241

    • Data Source
      KAKENHI-PROJECT-20249030
  • [Journal Article] Dysregulation of an IL-17-Triggered Positive Feedback Loop of IL-6 Signaling in an Autoimmune Arthritis.2008

    • Author(s)
      *Ogura, H., *M. Murakami, &T. Hirano, et al. (*equal contribution)
    • Journal Title

      Immunity 29

      Pages: 628-636

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Journal Article] Combination treatment with IL-2 and anti-IL-2 mAbs reduces tumor metastasis via NK cell activation2008

    • Author(s)
      Jin, G., T. Hirano, M. Murakami.
    • Journal Title

      International Immunology 20

      Pages: 783-789

    • NAID

      10021241636

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Journal Article] Intracellular Zinc homeostasis and Zinc signaling.2008

    • Author(s)
      Murakami, M., T. Hirano.
    • Journal Title

      Cancer Science (in press)

    • NAID

      10024009265

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Journal Article] Roles of Zinc and Zinc signaling in immunity : Zinc is an intracellular signaling molecule.2008

    • Author(s)
      T. Hirano, et al.
    • Journal Title

      Adavanced Immunology (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Journal Article] intracellular Zinc homeostasis and Zinc signaling.2008

    • Author(s)
      Murakami M., T. Hirano.
    • Journal Title

      Cancer Science (in press)

    • NAID

      10024009265

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Journal Article] Roles of Zinc and Zinc signaling in immunity : Zinc is an intracellular signaling molecule.2008

    • Author(s)
      Hirano, T., M. Murakami
    • Journal Title

      Adavances in Immunology 97

      Pages: 149-176

    • Data Source
      KAKENHI-PROJECT-20249030
  • [Journal Article] Combination treatment with IL-2 and anti-IL-2 mAbs reduces tumor metastasis via NK cell activation.2008

    • Author(s)
      Jin, G., T. Hirano, M. Murakami.
    • Journal Title

      International Immunology (in press)

    • NAID

      10021241636

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Journal Article] Intracellular Zinc homeostasis and Zinc signaling.2008

    • Author(s)
      Murakami M., T.Hirano
    • Journal Title

      Cancer Science 99

      Pages: 1515-1522

    • NAID

      10024009265

    • Data Source
      KAKENHI-PROJECT-20249030
  • [Journal Article] Intracellular Zinc homeostasis and Zinc signaling.2008

    • Author(s)
      Murakami, M., T. Hirano.
    • Journal Title

      Cancer Science 99

      Pages: 1515-1522

    • NAID

      10024009265

    • Data Source
      KAKENHI-PROJECT-20249030
  • [Journal Article] The zinc transporter SLC39A13/ZIP13 is required for connective tissue development; its involvement in BMP/TGF-beta signaling pathways.2008

    • Author(s)
      Fukada, T., T. Hirano, etal.
    • Journal Title

      PLoS ONE 3

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Journal Article] The Zinc Transporter SLC39A13/ZIP13 is Required for Connective Tissue Development ; Its Involvement in BMP/TGF-beta Signaling Pathways.2008

    • Author(s)
      Fukada T., N.Civic, T.Furuichi, S.Shimoda, K.Mishima, H.Higashiyama, Y.Idaira, Y.Asada, H.Kitamura, S.Yamasaki, S.Hojyo, M.Nakayama, O.Ohara, H.Koseki, H.G.dos Santos, L.Bonafe, R.Ha-Vinh, A.Zankl, S.Unger, M.E.Kraenzlin, J.S.Beckmann, I.Saito, C.Rivolta, S.Ikegawa, A.Superti-Furga, T.Hirano
    • Journal Title

      PLoS ONE 3(11)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Journal Article] Essential function for the calcium sensor STIM1 in mast cell activation and anaphylactic responses.2008

    • Author(s)
      Baba Y., K.Nishida, Y.Fujii, T.Hirano, M.Hikida, T.Kurosaki
    • Journal Title

      Nat.Immunol.Jan 9(1)

      Pages: 81-88

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Journal Article] Interaction of Scaffolding Adaptor Protein Gabl with Tyrosine Phosphatase SHP2 Negatively Regulates IGF-I-dependent Myogenic Differentiation via ERK1/2 Signaling Pathway.2008

    • Author(s)
      Koyama, T., T. Hirano, etal.
    • Journal Title

      J Biol Chem. 283

      Pages: 24234-24244

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Journal Article] Roles of Zinc and Zinc signaling in immunity : Zinc is an intracellular signaling molecule.2008

    • Author(s)
      Hirano T., M.Murakami, T.Fukada, K.Nishida, S.Yamasaki, T.Suzuki
    • Journal Title

      Ad.Immunol. 97

      Pages: 149-176

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Journal Article] Zinc and its transporter ZIP1O are involved in invasive behavior of breast cancer cells.2007

    • Author(s)
      Kagara, N., N.Tanaka, S.Noguchi, T.Hirano.
    • Journal Title

      Cnacer Science (in press)

    • Data Source
      KAKENHI-PROJECT-15002008
  • [Journal Article] An essential role for RasGRP1 in mast cell function and IgE-mediated allergic response.2007

    • Author(s)
      Liu, Y.・M., Zhu・K., Nishida・T., Hirano・W., Zhang.
    • Journal Title

      J. Exp. Med. 204

      Pages: 93-103

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Journal Article] Zinc and its transporter ZIP10 are involved in invasive behavior of breast cancer cells.2007

    • Author(s)
      Kagara, N.・N., Tanaka・S., Noguchi・ and T., Hirano.
    • Journal Title

      Cancer Science 98

      Pages: 692-697

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Journal Article] Homeostatic proliferating CD4 T cells are involved in the pathogenesis of an Omenn syndrome murine model.2007

    • Author(s)
      Khiong, K., M.Murakami, K.Ishihara, T.Hirano, et al.
    • Journal Title

      J. Clin. Invest (in press)

    • Data Source
      KAKENHI-PROJECT-15002008
  • [Journal Article] CD1d-restricted natural killer T cell activation enhanced homeostatic proliferation of CD8+T cells in a manner dependent on IL-4.2006

    • Author(s)
      Ueda, N., T.Hirano, M.Murakami, et al.
    • Journal Title

      Int. Immunol. 18

      Pages: 1397-1404

    • Data Source
      KAKENHI-PROJECT-15002008
  • [Journal Article] Toll-like receptor-mediated regulation of zinc homeostasis influences dendritic cell function.2006

    • Author(s)
      Kitamura, H., S. Yamashita, M. Murakami, T. Hirano, et al.
    • Journal Title

      Nature Immunol. 7

      Pages: 971-977

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Journal Article] Grasp a pTyr-peptide by its SOCS.2006

    • Author(s)
      Hirano, T., M. Murakami.
    • Journal Title

      Dev. Cell 10

      Pages: 542-544

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Journal Article] IL-2 in vivo activities and anti-tumor efficacy enhanced by an anti-IL-2 mAb.2006

    • Author(s)
      Kamimura, D., T.Hirano, M.Murakami, et al.
    • Journal Title

      J. Immunol. 177

      Pages: 306-314

    • Data Source
      KAKENHI-PROJECT-15002008
  • [Journal Article] TRIF-GEFH1-RhoB cascade regulates surface expression of MHC class II in dendritic cells that is critical for CD4+ T cell activation.2006

    • Author(s)
      Kamon, H., T.K.Ishihara, M., Murakami, T.Hirano, et al.
    • Journal Title

      EMBO J. 25

      Pages: 4108-4119

    • Data Source
      KAKENHI-PROJECT-15002008
  • [Journal Article] Toll-like receptor-mediated regulation of zinc homeostasis influences dendritic cell function.2006

    • Author(s)
      Kitamura, H., S.Yamashita, M.Murakami, T.Hirano, et al.
    • Journal Title

      Nature Immunol. 7

      Pages: 971-977

    • Data Source
      KAKENHI-PROJECT-15002008
  • [Journal Article] Autoimmune arthritis associated with mutated IL-6 receptor gp130 is driven by STAT3/IL-7-dependent homeostatic proliferation of CD4+ T.2006

    • Author(s)
      Sawa, S., Ishihara, M.Murakami, T.Hirano, et al.
    • Journal Title

      J. Exp. Med. 203

      Pages: 1459-1470

    • Data Source
      KAKENHI-PROJECT-15002008
  • [Journal Article] Zinc is required for FceRI-mediated mast cell activation.2006

    • Author(s)
      Kabu, K, T.Hirano, et al.
    • Journal Title

      J. Immunol. 177

      Pages: 1296-1305

    • Data Source
      KAKENHI-PROJECT-15002008
  • [Journal Article] FcεRI-mediated mast cell degranulation requires calcium-independent microtubule-dependent translocation of granules to the plasma membrane.2005

    • Author(s)
      Nishida, K., T.Hirano, et al.
    • Journal Title

      J.Cell Biol. 170

      Pages: 115-126

    • Data Source
      KAKENHI-PROJECT-15002008
  • [Journal Article] IL-6-STAT3 controls intracellular MHC classII αβ-dimer level through Cathepsin S activity in dendritic cells.2005

    • Author(s)
      Kitamura, H., T.Hirano, et al.
    • Journal Title

      Immunity 23

      Pages: 491-502

    • Data Source
      KAKENHI-PROJECT-15002008
  • [Journal Article] Roles of MITF for Development of Mast Cells in Mice : Effects on Both Precursors and Tissue Environments.2004

    • Author(s)
      Morii, E., T.Hirano, et al.
    • Journal Title

      Blood 104

      Pages: 1656-1661

    • Data Source
      KAKENHI-PROJECT-15002008
  • [Journal Article] Zinc finger gene fez-like functions in the formation of subplate neurons and thalamocortical axons.2004

    • Author(s)
      Hirata, T., T.Hirano, et al.
    • Journal Title

      Dev.Dyn. 230

      Pages: 546-556

    • Data Source
      KAKENHI-PROJECT-15002008
  • [Journal Article] STAT3 non-cell-autonomously controls planner cell polarity during zebrafish convergence and extention.2004

    • Author(s)
      Miyagi, C., T.Hirano, et al.
    • Journal Title

      J.Cell Biol. 166

      Pages: 975-981

    • Data Source
      KAKENHI-PROJECT-15002008
  • [Journal Article] Koyasu, A.Miyajima. Development of CD4+ Macrophages from Intrathymic T Cell Progenitors Is Induced by Thymic Epithelial Cell2004

    • Author(s)
      Esashi E, T.Hirano, et al.
    • Journal Title

      J Immunol. 173

      Pages: 4360-4367

    • Data Source
      KAKENHI-PROJECT-15002008
  • [Journal Article] Interleukin-6 edited by Martini, L., Academic Press2004

    • Author(s)
      Ohtani, T., T. Hirano.
    • Journal Title

      Encyclopedia of Endocrinology and Endocrine Diseases

      Pages: 64-70

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Journal Article] New IL-6 (gp130) family cytokine members, CLC/NNT1/BSF3 and IL-27.2004

    • Author(s)
      Murakami, M., D. Kamimura, T. Hirano.
    • Journal Title

      Growth Facotrs 22

      Pages: 75-77

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Journal Article] Gab1 contributes to cytoskeletal reorganization and chemotaxis in response to platelet-derived growth factor.2004

    • Author(s)
      Kallin, A., T.Hirano, et al.
    • Journal Title

      J.Biol.Chem. 279

      Pages: 17897-17904

    • Data Source
      KAKENHI-PROJECT-15002008
  • [Journal Article] Zinc transporter LIV1 controls epithelial-mesenchymal transition in zebrafish gastrula organizer.2004

    • Author(s)
      Yamashita, S., T.Hirano, et al.
    • Journal Title

      Nature 429

      Pages: 298-302

    • Data Source
      KAKENHI-PROJECT-15002008
  • [Journal Article] The point mutation of Y759 of the IL-6 family receptor gp130 synergizes with HTLV-1 pX in promoting RA-like arth2004

    • Author(s)
      Ishihara, K., T.Hirano, et al.
    • Journal Title

      Int.Immunol. 16

      Pages: 455-465

    • Data Source
      KAKENHI-PROJECT-15002008
  • [Journal Article] L-6 Regulates in vivo Dendritic Cell Differentiation through STAT3 Activation.2004

    • Author(s)
      Park, S.-J., T.Hirano, et al.
    • Journal Title

      J.Immunol. 173

      Pages: 3844-3854

    • Data Source
      KAKENHI-PROJECT-15002008
  • [Journal Article] Roles of MITF for Development of Mast Cells in Mice : Effects on Both Precursors and Tissue Environments.2004

    • Author(s)
      Morii, E., T. Hirano, et al.
    • Journal Title

      Blood 104

      Pages: 1656-1661

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Journal Article] Genetic evidence for involvement of maternally derived Wnt canonical signaling in dorsal determination in zebrafish.2004

    • Author(s)
      Nojima, H., T.Hirano, et al.
    • Journal Title

      Mech.Dev. 121

      Pages: 371-386

    • Data Source
      KAKENHI-PROJECT-15002008
  • [Journal Article] Expression of sax1/nkx1.2 and sax2/nkx1.1 in zebrafish.2004

    • Author(s)
      Bae, Y.-K., T.Hirano, et al.
    • Journal Title

      Gene Expr.Patterns 4

      Pages: 481-486

    • Data Source
      KAKENHI-PROJECT-15002008
  • [Journal Article] Downregulation of STAT3 activation is required for presumptive rod photoreceptor cells to differentiate in the postnatal retina.2004

    • Author(s)
      Ozawa, Y., T.Hirano, et al.
    • Journal Title

      Mol.Cell.Neurosci. 26

      Pages: 258-270

    • Data Source
      KAKENHI-PROJECT-15002008
  • [Journal Article] Evidence of a novel IL-2/15Rbeta-targeted cytokine involved in homeostatic proliferation of memory CD8+ T cells.2004

    • Author(s)
      Kamimura, D., T.Hirano, et al.
    • Journal Title

      J.Immunol. 173

      Pages: 6041-6049

    • Data Source
      KAKENHI-PROJECT-15002008
  • [Journal Article] IL-6 signal transduction and its physiological roles : The signal orchestration model.2003

    • Author(s)
      Kamimura, D., K. Ishihara, T. Hirano.
    • Journal Title

      Reviews of Physiology, Biochemistry and Pharmacology 149

      Pages: 1-38

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Journal Article] Interleukin-6, edited by Henry, H. L, and Norman, A. W. Academic Press2003

    • Author(s)
      Kamimura D., T. Hirano.
    • Journal Title

      Encyclopedia of Hormones

      Pages: 430-439

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Journal Article] The role of Gab family scaffolding adapter proteins in the signal transduction of cytokine and growth factor receptors.2003

    • Author(s)
      Nishida, K., T. Hirano.
    • Journal Title

      Cancer Science 94

      Pages: 1029-1033

    • NAID

      10012163848

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Journal Article] Mechanisms and biological roles of STAT activation by the IL-6 family of cytokines. edited by P. B. Sehgal, D. E. Levy and T. Hirano, Kluwer Academic Publishers2003

    • Author(s)
      Kamimura, D., T. Hirano.
    • Journal Title

      Signal Transducers and Activators of Transcription (STATs) : Activation and Biology

      Pages: 595-607

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Patent] 肥満細胞脱顆粒制御剤2006

    • Inventor(s)
      平野俊夫, 西田圭吾
    • Industrial Property Rights Holder
      平野俊夫, 西田圭吾
    • Filing Date
      2006-06-08
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Patent] 亜鉛イオンによる転写因子STATの活性制御(亜鉛によるSTAT転写因子の活性制御)2006

    • Inventor(s)
      平野俊夫, 村上正晃, 深田俊幸(理研、ゼリア新薬工業)
    • Industrial Property Rights Holder
      平野俊夫, 村上正晃, 深田俊幸(理研、ゼリア新薬工業)
    • Filing Date
      2006-11-28
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Patent] 未成熟樹状細胞の成熟化調節剤2005

    • Inventor(s)
      平野俊夫, 村上正晃
    • Industrial Property Rights Holder
      平野俊夫, 村上正晃
    • Patent Publication Number
      2005-015413
    • Acquisition Date
      2005-06-28
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] Interleukin 6 amplifier and autoimmune disease : a four step model2011

    • Author(s)
      平野俊夫
    • Organizer
      ESF-JSPS Frontier Science Conference Series for Researchers(平成22年度日本-欧州先端科学セミナー)"Cutting Edge Immunology and its Clinical Application"
    • Place of Presentation
      アポロホテル(オランダ)(招待講演)
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] A 4 Step Model in MHC Class II-Associated Autoimmune Diseases2011

    • Author(s)
      奥山祐子、上村大輔、平野俊夫、村上正晃, 他
    • Organizer
      International Symposium "Towards Comprehensive Understanding of Immune Dynamism"
    • Place of Presentation
      千里阪急ホテル
    • Year and Date
      2011-03-01
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] Zinc Prevents Th17 Cell-Mediated Autoimmune Disease by Directly Inhibiting STAT32011

    • Author(s)
      北林知佳、村上正晃、平野俊夫, 他
    • Organizer
      International Symposium "Towards Comprehensive Understanding of Immune Dynamism"
    • Place of Presentation
      千里阪急ホテル
    • Year and Date
      2011-03-01
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] International Symposium "Towards Comprehensive Understanding of Immune Dynamism", "Zinc Prevents Th17 Cell-Mediated Autoimmune Disease by Directly Inhibiting STAT3"2011

    • Author(s)
      C.Kitabayashi1, T.Fukada, M.Kanamoto, N.Ueda, W.Ohashi, S.Hojyo, I.Azuma, H.Hirota, M.Murakami, T.Hirano
    • Organizer
      Senri Hankyu Hotel & Osaka University
    • Place of Presentation
      Osaka
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] Foxp3^+CD8^+ T Cells Developed in an IL-6-Dependent Manner Control an Autoimmune Arthritis.2011

    • Author(s)
      鶴岡峰子、平野俊夫、村上正晃, 他
    • Organizer
      International Symposium "Towards Comprehensive Understanding of Immune Dynamism"
    • Place of Presentation
      千里阪急ホテル
    • Year and Date
      2011-03-01
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] Zinc signaling in bone and immunity2010

    • Author(s)
      平野俊夫
    • Organizer
      第7回Bone Biology Forum, 「亜鉛トランスポーターと骨」
    • Place of Presentation
      静岡県裾野市(招待講演)
    • Year and Date
      2010-08-21
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] Hepatic IL-7, which is Induced by TLR-Type I IFN Signaling, Promotes T cell Responses.2010

    • Author(s)
      澤幸久、上村大輔、平野俊夫、村上正晃, 他
    • Organizer
      第14回国際免疫学会議
    • Place of Presentation
      神戸国際会議場他
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] Zinc is an intracellular signaling molecule.2010

    • Author(s)
      平野俊夫
    • Organizer
      日本薬学会第20回「金属の関与する生体関連反応シンポジウム」
    • Place of Presentation
      徳島文理大学国際会議場(招待講演)
    • Year and Date
      2010-06-25
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] 亜鉛と免疫・アレルギー・炎症:亜鉛はシグナル伝達分子である2010

    • Author(s)
      平野俊夫
    • Organizer
      第109回日本皮膚科学会
    • Place of Presentation
      大阪国際会議場
    • Year and Date
      2010-04-17
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] IL-6 plays roles not only for developing Th17 but also for inducing an IL-6 amplifier in autoimmue diseases.2010

    • Author(s)
      小椋英樹、村上正晃、平野俊夫, 他
    • Organizer
      第14回国際免疫学会議
    • Place of Presentation
      神戸国際会議場他
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] 亜鉛と免疫・炎症・アレルギー:亜鉛はシグナル伝達因子である2010

    • Author(s)
      平野俊夫
    • Organizer
      第26回日本DDS (Drug Delivery System)学会
    • Place of Presentation
      大阪国際交流センター 特別講演
    • Year and Date
      2010-06-17
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] Zinc is an intracellular signaling molecule.2010

    • Author(s)
      平野俊夫
    • Organizer
      日本薬学会第20回「金属の関与する生体関連反応シンポジウム
    • Place of Presentation
      徳島文理大学国際会議場
    • Year and Date
      2010-06-25
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] Zinc and CD4+ T cell-mediatautoimmune diseases2010

    • Author(s)
      Masaaki Murakami, Chika Kitabayashi, Toshiyuki Fukada, Minoru Kanamoto, Wakana Ohashi, Shintaro Hojyo, Toru Atsumi, Naoko Ueda, Ichiro Azuma, Hiroshi Hirota, Tosh Hirano
    • Organizer
      The 60^<th> Fujihara Seminar Zinc Signaling and Cellular Functions
    • Place of Presentation
      OsakaInternational Convention Center
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] 亜鉛シグナルと免疫・アレルギー・炎症2010

    • Author(s)
      平野俊夫
    • Organizer
      JDDW2010-第52回日本消化器病学会大会
    • Place of Presentation
      パシフィコ横浜(招待講演)
    • Year and Date
      2010-10-13
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] 亜鉛シグナルと免疫・アレルギー・炎症2010

    • Author(s)
      平野俊夫
    • Organizer
      第三回埼玉抗IL-6療法研究会
    • Place of Presentation
      ホテルブリランテ武蔵野(招待講演)
    • Year and Date
      2010-12-01
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] A zinc finger motif containing protein regulates the activation of the IL-6 amplifier, which is a critical fo development of an autoimmune arthritis.2010

    • Author(s)
      Hideki Ogura, Masaya Harada, Eri Sanda, Yuko Okuyama, Daisuke Kamimura, Masaaki Murakmai, Toshio Hirano
    • Organizer
      The 60^<th> Fujihara Seminar Zinc Signaling and Cellular Functions
    • Place of Presentation
      Osaka International Convention Center
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] Zinc and Th17-mediated autoimmune diseases2010

    • Author(s)
      Masaaki Murakami, Chika Kitabayashi, Toshiyuki Fukada, Minoru Kanamoto, Wakana Ohashi, Shintaro Hojyo, Toru Atsumi, Naoko Ueda, Ichiro Azuma, Hiroshi Hirota, Toshio Hirano
    • Organizer
      The 60^<th> Fujihara Seminar Zinc Signaling and Cellular Functions
    • Place of Presentation
      Osaka International Convention Center
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] 亜鉛シグナルと免疫・アレルギー・炎症2010

    • Author(s)
      平野俊夫
    • Organizer
      第26回日本小児がん学会学術集会
    • Place of Presentation
      大阪国際会議場(招待講演)
    • Year and Date
      2010-12-18
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] A zinc finger motif containing protein regulates the activation of the IL-6 amplifier, which is a critical for the development of an autoimmune arthritis.2010

    • Author(s)
      小椋英樹、上村大輔、平野俊夫、村上正晃, 他
    • Organizer
      The 60th Fujihara Seminar Zinc Signaling and Cellular Functions
    • Place of Presentation
      大阪国際会議場
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] Zinc is an intracellular signaling molecule : early and late signal2010

    • Author(s)
      Toshio Hirano, M.Murakami, T.Fukada, K.Nishida, S.Yamasaki, S.Hojyo
    • Organizer
      The 60^<th> Fujihara Seminar Zinc Signaling and Cellular Functions
    • Place of Presentation
      Osaka International Convention Center
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] Homeostatic proliferation of CD4+ T cells is involved in the pathogenesis of a mouse model of Omenn syndrome.2010

    • Author(s)
      上村大輔、平野俊夫、村上正晃, 他
    • Organizer
      第14回国際免疫学会議
    • Place of Presentation
      神戸国際会議場他
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] An attempt to identify molecules, which intracellular localizations are regulated by Zinc.2010

    • Author(s)
      小林翔平、村上正晃、平野俊夫, 他
    • Organizer
      The 60th Fujihara Seminar Zinc Signaling and Cellular Functions
    • Place of Presentation
      大阪国際会議場
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] IFN-γ from CD8+ T cells, which is regulated by IL-6 signal, is involved in superantigen-mediated CD4+ T cell death.2010

    • Author(s)
      熱海徹、平野俊夫、村上正晃, 他
    • Organizer
      第14回国際免疫学会議
    • Place of Presentation
      神戸国際会議場他
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] Combination of IL-2 plus anti-IL-2 mAbs reduces cancer metastasis through activation of NK cells.2010

    • Author(s)
      有馬康伸、平野俊夫、村上正晃, 他
    • Organizer
      第14回国際免疫学会議
    • Place of Presentation
      神戸国際会議場他
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] IL-6-mediated STAT3 signaling in T cells directs the development of Th17 with a minimum effect on that of Treg in vivo.2010

    • Author(s)
      原田誠也、村上正晃、平野俊夫, 他
    • Organizer
      第14回国際免疫学会議
    • Place of Presentation
      神戸国際会議場他
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] 亜鉛シグナルと免疫・アレルギー・炎症(Zinc signaling in immunity, allergy and inflammation)2010

    • Author(s)
      平野俊夫
    • Organizer
      JDDW2010-第52回日本消化器病学会大会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2010-10-13
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] Zinc-mediated STAT3 suppression is involved in inhibition of autoimmune disease development via regulating Th17 differentiation.2010

    • Author(s)
      Chika Kitabayashi, Toshiyuki Fukada, Minoru Kanamoto, Wakana Ohashi, Shintaro Hojyo, Toru Atsumi, Naoko Ueda, Ichiro Azuma, Hiroshi Hirota, Masaaki Murakami, Toshio Hirano
    • Organizer
      14^<th> International Congress of Immunology (第14回国際免疫学会議)
    • Place of Presentation
      Kobe, Japan
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] Regulation of T cell Activation via a Metal Transporter2010

    • Author(s)
      諸井亜理沙、上村大輔、平野俊夫、村上正晃, 他
    • Organizer
      The 60th Fujihara Seminar Zinc Signaling and Cellular Functions
    • Place of Presentation
      大阪国際会議場
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] IL-6-meidated positive regulation of Foxp3+CD8+ T cells is critical for the development of autoimmune diseases.2010

    • Author(s)
      鶴岡峰子、平野俊夫、村上正晃, 他
    • Organizer
      第14回国際免疫学会議
    • Place of Presentation
      神戸国際会議場他
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] Zinc and Th17-mediated autoimmune diseases2010

    • Author(s)
      村上正晃、平野俊夫, 他
    • Organizer
      The 60th Fujihara Seminar Zinc Signaling and Cellular Functions
    • Place of Presentation
      大阪国際会議場
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] 亜鉛と免疫・炎症・アレルギー:亜鉛はシグナル伝達因子である2010

    • Author(s)
      平野俊夫
    • Organizer
      第26回日本DDS(Drug Delivery System)学会
    • Place of Presentation
      大阪国際交流センター(招待講演)
    • Year and Date
      2010-06-17
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] Specific antigen recognition by CD4+ T cells is not required for a MHC class II-associated autoimmune arthritis.2010

    • Author(s)
      奥山祐子、上村大輔、村上正晃、平野俊夫, 他
    • Organizer
      第14回国際免疫学会議
    • Place of Presentation
      神戸国際会議場他
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] Zinc is an intracellular signaling molecule : early and late signal2010

    • Author(s)
      平野俊夫
    • Organizer
      The 60th Fujihara Seminar Zinc Signaling and Cellular Functions
    • Place of Presentation
      大阪国際会議場
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] Regulati of T cell Activation via a Metal on Transporter2010

    • Author(s)
      Arisa Moroi, Daisuke Kamimura, Kokic Katsunuma, Yukihisa Sawa, Yukihisa Sawa, Toshio Hirano
    • Organizer
      The 60^<th> Fujihara Seminar Zinc Signaling and Cellular Functions
    • Place of Presentation
      Osaka International Convention Center
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] JSI symposium at IMMUNOLOGY 20102010

    • Author(s)
      平野俊夫
    • Organizer
      Regulation of immune response by cytokine and zinc signaling
    • Place of Presentation
      Bethesda, USA
    • Year and Date
      2010-05-08
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] 亜鉛と亜鉛トランスポーター:サイトカイン/増因子の情報伝達と病態形成への関与(Zinc and its transporters : Their roles in intracellular signaling and diseases)2010

    • Author(s)
      深田俊幸、北條慎太郎、北林千佳、大橋若奈、村上正晃、平野俊夫
    • Organizer
      第75回インターフェロン・サイトカイン学会・学術集会
    • Place of Presentation
      北九殖州国際会議場(北九州市)
    • Year and Date
      2010-06-26
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] 亜鉛と免疫・炎症・アレルギー:亜鉛はシグナル伝達分子である(Zinc signaling in immunity, allergy and inflammation)2010

    • Author(s)
      平野俊夫
    • Organizer
      日本薬学会第130年会
    • Place of Presentation
      岡山コンベンションセンター、岡山大学、就実大学他 特別講演
    • Year and Date
      2010-03-29
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] Zinc and CD4+T cell-mediated autoimmune diseases2010

    • Author(s)
      村上正晃、平野俊夫, 他
    • Organizer
      The 60th Fujihara Seminar Zinc Signaling and Cellular Functions
    • Place of Presentation
      大阪国際会議場
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] 亜鉛シグナルと免疫・アレルギー・炎症2010

    • Author(s)
      平野俊夫
    • Organizer
      第26回日本小児がん学会学術集会
    • Place of Presentation
      大阪国際会議場
    • Year and Date
      2010-12-18
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] 亜鉛と免疫・炎症・アレルギー : 亜鉛はシグナル伝達分子である2010

    • Author(s)
      平野俊夫
    • Organizer
      日本薬学会第130年会
    • Place of Presentation
      岡山大学、就実大学他
    • Year and Date
      2010-03-29
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] Zinc-mediated STAT3 suppression is involved in inhibition of autoimmune disease development via regulating Th17 differentiation.2010

    • Author(s)
      北林知佳、村上正晃、平野俊夫, 他
    • Organizer
      第14回国際免疫学会議
    • Place of Presentation
      神戸国際会議場他
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] 亜鉛と亜鉛トランスポーター:サイトカイン/増殖因子の情報伝達と病態形成への関与2010

    • Author(s)
      深田俊幸、村上正晃、平野俊夫, 他
    • Organizer
      第75回インターフェロン・サイトカイン学会・学術集会
    • Place of Presentation
      北九州国際会議場(招待講演)
    • Year and Date
      2010-06-26
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] インターロイキン6増幅回路と自己免疫疾患・慢性炎症性疾患2010

    • Author(s)
      平野俊夫
    • Organizer
      第54回日本リウマチ学会総会・学術集会
    • Place of Presentation
      神戸ポートピアホテル(招待講演)
    • Year and Date
      2010-04-24
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] Regulation of immune response by cytokine and zinc signaling2010

    • Author(s)
      平野俊夫
    • Organizer
      JSI symposium at IMMUNOLOGY 2010
    • Place of Presentation
      ベセスダ(アメリカ)(招待講演)
    • Year and Date
      2010-05-08
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] Zinc siganaling in bone and immunity2010

    • Author(s)
      平野俊夫
    • Organizer
      第7回Bone Biology Forum (BBF)
    • Place of Presentation
      静岡県裾野市富士教育研修所
    • Year and Date
      2010-08-21
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] 亜鉛と免疫・アレルギー・炎症:亜鉛はシグナル伝達分子である2010

    • Author(s)
      平野俊夫、村上正晃, 他
    • Organizer
      第109回日本皮膚科学会
    • Place of Presentation
      大阪国際会議場(招待講演)
    • Year and Date
      2010-04-17
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] Metallothionein I/II分子によるCD4+T細胞依存性の自己免疫疾患の抑制機序2009

    • Author(s)
      三田恵理、小椋英樹、熱海徹、村上正晃、平野俊夫
    • Organizer
      第39回日本免疫学会総会・19学術集会
    • Place of Presentation
      大阪国際会議場
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] 亜鉛と免疫・アレルギー炎症:亜鉛は細胞内シグナル伝達因子である2009

    • Author(s)
      平野俊夫
    • Organizer
      第33回皮膚科免疫セミナー
    • Place of Presentation
      品川プリンスホテルメインタワー
    • Year and Date
      2009-03-09
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] インターロイキン6ハンティング2009

    • Author(s)
      平野俊夫
    • Organizer
      第74回日本インターフェロン・サイトカイン学会学術総会
    • Place of Presentation
      京都大学
    • Year and Date
      2009-06-26
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] 亜鉛と免疫・アレルギー・炎症 : 亜鉛はシグナル伝達分子である2009

    • Author(s)
      平野俊夫
    • Organizer
      第415回日本皮膚科学会大阪地方会
    • Place of Presentation
      朝日生命ホール(大阪府)
    • Year and Date
      2009-10-03
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] Zinc prevents Th17 cell-mediated autoimmune disease by directly inhibiting STAT3.2009

    • Author(s)
      Chika Kitabayashi, Toshiyuki Fukada, Minoru Kanamoto, Naoko Ueda, Wakana Ohashi, Shintaro Hojyo, Ichiro Azuma, Hiroshi Hirota, Masaaki Murakami, Toshio Hirano
    • Organizer
      第39回日20本免疫学会総会・学術集会
    • Place of Presentation
      大阪国際会議場
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] Is Dysregulation of IL-6 Amplifier a Key Event of Rheumatoid Arthritis?2009

    • Author(s)
      平野俊夫
    • Organizer
      第9回国際炎症学会
    • Place of Presentation
      東京京王プラザホテル
    • Year and Date
      2009-07-07
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] シグナル分子としての亜鉛2009

    • Author(s)
      平野俊夫
    • Organizer
      2009年日本農芸化学会大会シンポジウム「亜鉛バイオロジーの新展開」
    • Place of Presentation
      福岡国際会議場
    • Year and Date
      2009-03-29
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] 亜鉛と免疫・アレルギー・炎症:亜鉛はシグナル伝達分子である2009

    • Author(s)
      平野俊夫
    • Organizer
      第415回日本皮膚科学会大阪地方会第16回小林浩記念講演
    • Place of Presentation
      朝日生命ホール(大阪府)
    • Year and Date
      2009-10-03
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] Roles of zinc and zinc signaling in immune response2008

    • Author(s)
      Hirano, T.
    • Organizer
      Kick-off symposium of WPI IFReC - Immunology and Imaging-
    • Place of Presentation
      Osaka International Convention Center, Japan.
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] Roles of zinc and its transporters in immunity and connective a tissues2008

    • Author(s)
      平野俊夫
    • Organizer
      5^<th> The International Investigative Dermatology 2008, Luncheon Seminr(第五回国際研究皮膚科学会議)・ランチョンセミナー(協和発酵工業((株)))
    • Place of Presentation
      Kyoto International Conference Center(国立京都国際会館), Kyoto, Japan
    • Year and Date
      2008-05-17
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] Roles of zinc and zinc signaling in immune response2008

    • Author(s)
      平野俊夫
    • Organizer
      免疫フロンティア研究センターシンポジウム
    • Place of Presentation
      大阪国際会議場
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] Roles of zinc and its transporters in immunity and connective tissues.2008

    • Author(s)
      平野俊夫
    • Organizer
      RCAI-JSI International S mposium on Imm ology.
    • Place of Presentation
      Yokohama, Japan
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] Zinc suppresses Th17-mediated autoimmune diseases via inhibition of STAT3 activation.2008

    • Author(s)
      Chika Kitabayashi, Minoru Kanamoto, Toshiyuki Fukada, Masaaki Murakami, Toshio Hirano
    • Organizer
      第38回日本免疫学会総会・学術集会
    • Place of Presentation
      国立京都国際会館
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] 亜と免疫・発生・炎症2008

    • Author(s)
      平野俊夫
    • Organizer
      第29回日本炎症・再生医学会-教育講演I
    • Place of Presentation
      都市センターホテル(東京都)
    • Year and Date
      2008-07-09
    • Data Source
      KAKENHI-PROJECT-20249030
  • [Presentation] Immunity, allergy, and zinc : Zinc is a new intracellular signal messenger2007

    • Author(s)
      Hirano, T.
    • Organizer
      Osaka digestion forum, Special lecture
    • Place of Presentation
      Osaka, Japan.
    • Year and Date
      2007-07-13
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] IL-6-gpl30-STAT3 signaling plays roles in autoimmune disease through regulating T cell homeostatic proliferation and Thl7 development.2007

    • Author(s)
      平野俊夫
    • Organizer
      5th International Symposium on ″Cytokine signalling
    • Place of Presentation
      Aachen, Germany
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] Regulation of allergy and immune system by zinc2007

    • Author(s)
      Hirano, T.
    • Organizer
      The 12^<th> “The treatment society for nosal allergy"
    • Place of Presentation
      Senri Life Science Center, Japan.
    • Year and Date
      2007-06-30
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] 免疫にとっての自己とは? 非自己とは?2007

    • Author(s)
      平野俊夫
    • Organizer
      科学ゼミナール
    • Place of Presentation
      電力館(東京電力)
    • Year and Date
      2007-09-08
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] 亜鉛と免疫・アレルギー2007

    • Author(s)
      平野俊夫
    • Organizer
      第19回日本アレルギー学会春季臨床大会 特別プログラム
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2007-06-10
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] Zinc is an intracellular signaling molecule.2007

    • Author(s)
      Hirano T.
    • Organizer
      ISM 2007(International Symposium on Metallomics 2007). Keynote lecture
    • Place of Presentation
      Nagoya, Japan.
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] From Interleukin-6 to Zinc Signaling in Immune Responses : Zn2+is a Novel Intracellular Second Messenger2007

    • Author(s)
      平野俊夫
    • Organizer
      International Symposium, Lymphocyte DecodingTheir Development and Function
    • Place of Presentation
      東京
    • Year and Date
      2007-03-23
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] From Interleukin-6 to Zinc Signaling in Immune Responses : Zn2+ is a Novel Intracellular Second Messenger2007

    • Author(s)
      Hirano, T.
    • Organizer
      International Symposium, Lymphocyte Decoding Their Development and Function
    • Place of Presentation
      Tokyo, Japan.
    • Year and Date
      2007-03-23
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] Zinc signaling in dendritic cells.2007

    • Author(s)
      Hirano, T.
    • Organizer
      The 20^<th> Naito Conference on Innate Immunity in Medicine and Biology [III], Shonan Village Center
    • Place of Presentation
      Kanagawa, Japan.
    • Year and Date
      2007-10-11
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] Zinc and interleukin 6 signaling in immune responses : Zn2+is a novel intracellular second messenger2007

    • Author(s)
      平野俊夫
    • Organizer
      高津先生退官記念シンポジウム
    • Place of Presentation
      東京大学医科学研究所講堂
    • Year and Date
      2007-03-23
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] Aberrant cytokine signaling and autoimmune disease.2007

    • Author(s)
      Hirano, T.
    • Organizer
      The 27^<th> General Assembly of The Japan Medical Congress, Special Lecture, Immune system and its disruption-For understanding higher complex immune system
    • Place of Presentation
      Osaka International Convention Center, Japan.
    • Year and Date
      2007-04-06
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] Role of zinc and zinc signaling in immunity : Zn is an intracellular second messenger.2007

    • Author(s)
      Hirano, T.
    • Organizer
      2007 International Mucosal Immunity, Evening Seminar
    • Place of Presentation
      Shinagawa Prince Hotel, Tokyo, Japan.
    • Year and Date
      2007-07-11
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] IL-6-gp130-STAT3 signaling plays roles in autoimmune disease through regulating T cell homeostatic proliferation and Th17 development.2007

    • Author(s)
      Hirano, T.
    • Organizer
      5th International Symposium on "Cytokine signalling"
    • Place of Presentation
      Aachen, Germany.
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] Does Zinc signaling exist? : Zinc is a new second messenger.2007

    • Author(s)
      Hirano, T.
    • Organizer
      The 24^<th> Trace Nutrients Research Symposium, Special Lecture
    • Place of Presentation
      Kyoto Research Park, Japan.
    • Year and Date
      2007-06-07
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] Zinc and immunity_allergy2007

    • Author(s)
      Hirano, T.
    • Organizer
      The 19^<th> Spring Meeting of Japanese Society of Allergology, Special Program
    • Place of Presentation
      Pacifico Yokohama, Japan.
    • Year and Date
      2007-06-10
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] 亜鉛によるアレルギー・免疫制御2007

    • Author(s)
      平野俊夫
    • Organizer
      第12回「鼻アレルギー治療研究会」
    • Place of Presentation
      千里ライフサイエンスセンター
    • Year and Date
      2007-06-30
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] 免疫・アレルギーと亜鉛 : 亜鉛は細胞内シグナル伝達分子である2007

    • Author(s)
      平野俊夫
    • Organizer
      大阪消化器フォーラム 特別講演
    • Place of Presentation
      大阪
    • Year and Date
      2007-07-13
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] 亜鉛シグナルは存在するか? : 亜鉛は新しいセカンドメッセンジャーである。2007

    • Author(s)
      平野俊夫
    • Organizer
      第24回日本微量元素研究会シンポジウム特別講演
    • Place of Presentation
      京都リサーチパーク
    • Year and Date
      2007-06-07
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] Zinc and interleukin-6 signaling in immune responses : Zn2+ is a novel intracellular second messenger2007

    • Author(s)
      Hirano, T.
    • Organizer
      Prof. Takatsu retirement commemoration symposium
    • Place of Presentation
      The Institute of Medical Science, The University of Tokyo, Japan.
    • Year and Date
      2007-03-23
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] サイトカインシグナル異常と自己免疫疾患2007

    • Author(s)
      平野俊夫
    • Organizer
      第27回日本医学会総会 特別講演
    • Place of Presentation
      大阪国際会議場
    • Year and Date
      2007-04-06
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] Zinc is an intracellular signaling molecule.2007

    • Author(s)
      平野俊夫
    • Organizer
      International Symposium on Metallomics 2007(ISM 2007). Keynote lecture
    • Place of Presentation
      Nagoya, Japan
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] Role of zinc and zinc signaling in immunity : Zn is an intracellular second messenger.2007

    • Author(s)
      平野俊夫
    • Organizer
      2007 International Mucosal Immunity. (第13回国際粘膜免疫学会イブニングセミナー)
    • Place of Presentation
      Shinagawa Prince Hotel, Tokyo
    • Year and Date
      2007-07-11
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] サイトカインシグナルから亜鉛シグナル研究へ : 免疫アレルギー・発生・がん研究の橋渡し2006

    • Author(s)
      平野俊夫
    • Organizer
      第86回北海道医学大会総会 特別講演
    • Place of Presentation
      札幌グランドホテル
    • Year and Date
      2006-09-30
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] Zinc signaling regulates epithelial-mesenchymal transition.2006

    • Author(s)
      平野俊夫
    • Organizer
      The 37th International Symposium of the Princess Takamatsu Cancer Research Fund
    • Place of Presentation
      東京
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] Zinc and dendritic cell maturation : Does zinc act as a signaling molecule?2006

    • Author(s)
      平野俊夫
    • Organizer
      The 36^<th> Annual Meeting of the Japanese Society for Immunology, International Symposium
    • Place of Presentation
      大阪
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] Fc ε RI-mediated mast cell degranulation requires calcium-independent microtubule-dependent translocation of granules to the plasma membrane : Zinc-dependent pathway2006

    • Author(s)
      平野俊夫
    • Organizer
      RCAI-JSI International Symposium on Immunology 2006
    • Place of Presentation
      Hamagin Hall Via Mare, Yokohama
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] Roles of zinc in development, immunity and cancer : Does Zn function as a signaling molecule?2006

    • Author(s)
      平野俊夫
    • Organizer
      The Osaka University Forum in San Diego
    • Place of Presentation
      San Diego, U. S. A.
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] Zinc signaling regulates epithelial-mesenchymal transition and activation of immune cells : Zinc is a novel second messenger?2006

    • Author(s)
      平野俊夫
    • Organizer
      The Japan Society for Promotion of Scienceand the National Institutes of Heath are planning to hold the first joint symposium
    • Place of Presentation
      NIH Bethesda, U. S. A.
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] Roles of zinc in development, immunity and cancer : Does Zn function as a signaling molecule?2006

    • Author(s)
      Hirano, T.
    • Organizer
      The Osaka University Forum in San Diego.
    • Place of Presentation
      San Diego, U.S.A.
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] Cytokines, growth factors, and zinc for immunity, embryo, and cancer : Can zinc act as siganal molecule?2006

    • Author(s)
      Hirano, T.
    • Organizer
      The 71th Annual Meeting of The Japanese Society for Interferon and Cytokine Research
    • Place of Presentation
      Heisei memorial hall of Hyogo College of Medicine, Japan.
    • Year and Date
      2006-07-08
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] Zinc and dendritic cell maturation : Does zinc act as a signaling molecule?2006

    • Author(s)
      Hirano, T.
    • Organizer
      The 36^<th> Annual Meeting of the Japanese Society for Immunology, International Symposium
    • Place of Presentation
      Osaka, Japan.
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] 新しいマスト細胞脱顆粒抑制剤の開発の可能性2006

    • Author(s)
      平野俊夫
    • Organizer
      花粉症研究シンポジウム-花粉症克服へ向けた最新研究動向-
    • Place of Presentation
      ヤクルトホール、東京都
    • Year and Date
      2006-01-17
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] What is self, or non-self for immune system?2006

    • Author(s)
      Hirano, T.
    • Organizer
      Fiscal 2006 Senri Life Science Form
    • Place of Presentation
      Senti Clab, Japan.
    • Year and Date
      2006-10-27
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] 免疫にとっての自己とは? 非自己とは?2006

    • Author(s)
      平野俊夫
    • Organizer
      平成18年度千里ライフサイエンスフォーラム
    • Place of Presentation
      千里クラブ
    • Year and Date
      2006-10-27
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] Zinc signaling regulates epithelial-mesenchymal transition2006

    • Author(s)
      Hirano, T.
    • Organizer
      The 37th International Symposium of the Princess Takamatsu Cancer Research Fund "Cancer Micrioenviromnents"
    • Place of Presentation
      Tokyo, Japan
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] Zinc signaling regulates epithelial-mesenchymal transition and activation of immune cells : Zinc is a novel second messenger?2006

    • Author(s)
      Hirano, T.
    • Organizer
      The Japan Society for Promotion of Science and the National Institutes of Heath are planning to hold the first joint symposium.
    • Place of Presentation
      NIH Bethesda, U.S.A.
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] Potentiality for discovering new inhibitors of mast cell degranulation.2006

    • Author(s)
      Hirano, T.
    • Organizer
      Pollinosis research symposium-The latest research trend for overcoming pollinosis
    • Place of Presentation
      Yakult Hall, Japan.
    • Year and Date
      2006-01-17
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] サイトカインシグナルから亜鉛シグナル研究へ : 免疫・発生・がん研究の橋渡し2006

    • Author(s)
      平野俊夫
    • Organizer
      第9回免疫ワークショップ学術集会
    • Place of Presentation
      芝蘭会館、京都
    • Year and Date
      2006-04-01
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] What is self, or non-self for immune system?2006

    • Author(s)
      Hirano, T.
    • Organizer
      Tennohji high school super science school
    • Place of Presentation
      International House, Osaka, Japan.
    • Year and Date
      2006-09-14
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] 免疫にとっての自己とは? 非自己とは?2006

    • Author(s)
      平野俊夫
    • Organizer
      天王寺高等学校スーパーサイエンススクール
    • Place of Presentation
      大阪国際交流センター大ホール
    • Year and Date
      2006-09-14
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] 免疫、発生、がんにおけるサイトカイン・増殖因子シグナルと亜鉛 : 亜鉛はシグナル分子として作用しうるか?2006

    • Author(s)
      平野俊夫
    • Organizer
      第71回日本インターフェロンサイトカイ学会学術集会
    • Place of Presentation
      兵庫医科大学平成記念会館
    • Year and Date
      2006-07-08
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] Fc ε RI-mediated mast cell degranulation requires calcium-independent microtubule-dependent translocation of granules to the plasma membrane : Zinc-dependent pathway.2006

    • Author(s)
      Hirano, T.
    • Organizer
      RCAI-JSI International Symposium on Immunology 2006, Regulation of Immune Responses in Allergy and Inflammation
    • Place of Presentation
      Hamagin Hall Via Mare, Yokohama, Japan.
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] From cytokine signaling to Zinc signaling : Bridge of the researches of immunity, embryo, and cancer.2006

    • Author(s)
      Hirano, T.
    • Organizer
      The 9^<th> Science Meeting of immune workshop
    • Place of Presentation
      Shirankaikan, Japan.
    • Year and Date
      2006-04-01
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] From cytokine signaling to Zinc signaling : Bridge of the researches of immunity, embryo, and cancer.2006

    • Author(s)
      Hirano, T.
    • Organizer
      The 86^<th> Annual- Meeting of Hokkaido Medical Congress, Special Lecture
    • Place of Presentation
      Sapporo Grand Hotel, Japan.
    • Year and Date
      2006-09-30
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] Interaction of activated IL-6 producing CD4^+ T cell with non-hematopoietic tissues having gp130 mutation causes a rheumatoid arthritis-like disease.2005

    • Author(s)
      Hirano, T.
    • Organizer
      RCAI-JSI International Symposium on Immunology 2005, "Mechanisms of Immune Responses in Health and Diseases"
    • Place of Presentation
      Pacifico Yokohama, Japan.
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] Zinc transporter Liv1, a target of Stat3, controls epithelial-mesenchymal transition through regulating nuclear localization of snail2005

    • Author(s)
      平野俊夫
    • Organizer
      The 58th Annual Meeting of Japan Society for Cell Biology (JSCB58)
    • Place of Presentation
      Omiya Sonic City, Saitama
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] Zinc transporter Liv1, a target of Stat3, controls epithelial-mesenchymal transition through regulating nuclear localization of snail.2005

    • Author(s)
      Hirano, T.
    • Organizer
      The 58th Annual Meeting of Japan Society for Cell Biology (JSCB58)
    • Place of Presentation
      Omiya Sonic City, Saitama, Japan.
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] Cytokines and rheumatism2005

    • Author(s)
      Hirano, T.
    • Organizer
      The 16^<th> Science Meeting of Kanto branch of Japan College of Rheumatology. Symposium 2 “From Immunobiology to Rheumatology"
    • Place of Presentation
      Tsukuba International Congress Center, Japan.
    • Year and Date
      2005-12-10
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] Interaction of activated IL-6 producing CD4^+ T cell with non-hematopoietic tissues having gpl30 mutation causes a rheumatoid arthritis-like disease2005

    • Author(s)
      平野俊夫
    • Organizer
      RCAI-JSI International Symposium on Immunology 2005
    • Place of Presentation
      Pacifico Yokohama
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] Interaction of activated IL-6 producing CD4+T cells with non-hematopoietic tissues having a gp130 mutation causes a rheumatoid arthritis-like disease.2005

    • Author(s)
      Hirano, T.
    • Organizer
      Mini-Symposium on Cytokine Research, Institute of Biomedical Sciences Academia Sinica
    • Place of Presentation
      Taipei.
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] Interaction of activated IL-6 producing CD4十T cells with non-hematopoietic tissues having a gpl30 mutation causes a rheumatoid arthritis-like disease.2005

    • Author(s)
      平野俊夫
    • Organizer
      Mini-Symposium on Cytokine Research, Institute of Biomedical Sciences Academia Sinica
    • Place of Presentation
      Taipei
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] サイトカインとリウマチ2005

    • Author(s)
      平野俊夫
    • Organizer
      第16回日本リウマチ学会関東支部学術集会 シンポジウム2
    • Place of Presentation
      つくば国際会議場第1会場
    • Year and Date
      2005-12-10
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] サイトカインの分子生物学的研究2004

    • Author(s)
      平野俊夫
    • Organizer
      藤原賞受賞記念講演
    • Place of Presentation
      学士院会館
    • Year and Date
      2004-06-17
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] Development of autoimmune rheumatoid arthritis like disease by abnormal signaling of IL=6 family cytokine.2004

    • Author(s)
      平野俊夫
    • Organizer
      東北大学21世紀COEプログラム第1[回国際シンポジウム“Lymphocyte Development and Immunological Disorders"
    • Place of Presentation
      東北大学大学院医学系研究科
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] Zn transpoter LIV1, a new player in epithelial mesenchymal transition in zebrafish gastrulation.2004

    • Author(s)
      Hirano, T.
    • Organizer
      RCAI CDB Joint Form
    • Place of Presentation
      1st floor of Building C, CDB, Japan.
    • Year and Date
      2004-10-26
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] Zn transporter LIV1, a new player of epithelial-mesenchymal transition2004

    • Author(s)
      Hirano, T.
    • Organizer
      Symposium 「The Forefront of B Cell Research」
    • Place of Presentation
      The Institute of Medical Science, The University of Tokyo, Japan.
    • Year and Date
      2004-10-19
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] Research on Molecular Mechanisms of Cytokine.2004

    • Author(s)
      Hirano, T.
    • Organizer
      The Fujihara Award Winning commemoration lecture
    • Place of Presentation
      Gakushikaikan, Tokyo, Japan.
    • Year and Date
      2004-06-17
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] Self/non-self recognition by the immune system : Its invertibility.2004

    • Author(s)
      Hirano, T.
    • Organizer
      The 44^<th> Summer school workshop for young biochemist
    • Place of Presentation
      National Olympics Memorial Youth Center, Japan.
    • Year and Date
      2004-08-20
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] Development of autoimmune rheumatoid arthritis-like disease by abnormal signaling of IL=6 family cytokine.2004

    • Author(s)
      Hirano, T.
    • Organizer
      Tohoku University 21^<st> century COE Program, The 1st International Symposium
    • Place of Presentation
      Graduate School of Medicine, Tohoku University, Japan
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] Interleukin-6 research : Bridge of the researches of immunity, embryo, and cancer.2004

    • Author(s)
      Hirano, T.
    • Organizer
      The 13^<th> Tokyo immune forum. Special lecture
    • Place of Presentation
      The Institute of Medical Science, The University of Tokyo, Japan.
    • Year and Date
      2004-05-18
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] Zn transporter LIV1, a new player of epithelial-mesenchymal transition2004

    • Author(s)
      平野俊夫
    • Organizer
      RCAI CDB Joint Form
    • Place of Presentation
      1st floor of Building C, CDB
    • Year and Date
      2004-10-26
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] 原腸陥入におけるEpithelial-Mesenchymal Transitionの分子機構 : STAT3/LIV1亜鉛輸送蛋白/Snailの役割2004

    • Author(s)
      平野俊夫
    • Organizer
      OBIセミナー
    • Place of Presentation
      大阪バイオサイエンス研究所
    • Year and Date
      2004-09-24
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] インターロイキン6研究 : 免疫、発生、癌研究の橋渡し2004

    • Author(s)
      平野俊夫
    • Organizer
      第1 3回東京免疫フォーラム 特別講演
    • Place of Presentation
      東大医科研・講堂
    • Year and Date
      2004-05-18
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] Zn transporter LIV1, a new player of epithelial-mesenchymal transition2004

    • Author(s)
      平野俊夫
    • Organizer
      シンポジウム「The Forefront of B Cell Research」
    • Place of Presentation
      東京大学医科学研究所
    • Year and Date
      2004-10-19
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] 原腸陥入におけるEpithelial-Mesenchymal Transitionの分子機構 : 細胞の可動性を制御する乳がん関連分子、LIV1亜鉛輸送蛋白の役割2004

    • Author(s)
      平野俊夫
    • Organizer
      国立癌センター講演
    • Place of Presentation
      国立癌センター
    • Year and Date
      2004-06-18
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] 免疫における自己、非自己認識 : その可塑性2004

    • Author(s)
      平野俊夫
    • Organizer
      第44回生化学若手の会夏の学校ワークショップ
    • Place of Presentation
      国立オリンピック記念青少年総合センター
    • Year and Date
      2004-08-20
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] Molecular mechanism of Epithelial-Mesenchymal-Transition in gastrulation : roles of Zn transporter LIV1, a breast cancer-related molecule regulating cell motility.2004

    • Author(s)
      Hirano, T.
    • Organizer
      “Roles of Zn transporter LIV1" National Cancer Center Seminar
    • Place of Presentation
      National Cancer Center Seminar, Japan.
    • Year and Date
      2004-06-18
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] Molecular mechanism of Epithelial-Mesenchymal Transition in gastrulation : Roles of STAT3/ Zn transporter LIV1/Snail.2004

    • Author(s)
      Hirano, T.
    • Organizer
      OBI Seminar
    • Place of Presentation
      Osaka Bioscience Institute, Japan.
    • Year and Date
      2004-09-24
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] インターロイキン6シグナル異常と自己免疫疾患、特に関節リウマチについて2003

    • Author(s)
      平野俊夫
    • Organizer
      千里ライフサイエンスシンポジウム
    • Place of Presentation
      千里ライフサイエンスセンター
    • Year and Date
      2003-09-02
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] Aberrant signal of gp130 and rheumatoid arthritis-like disease2003

    • Author(s)
      Hirano, T.
    • Organizer
      The 26^<th> General Assembly of The Japan Medical Congress
    • Place of Presentation
      Fukuoka International Convention Center, Fukuoka, Japan.
    • Year and Date
      2003-04-04
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] Gpl30シグナル異常と慢性関節リウマチ様自己免疫疾患2003

    • Author(s)
      平野俊夫
    • Organizer
      第26回日本医学会総会
    • Place of Presentation
      福岡国際会議場
    • Year and Date
      2003-04-04
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] Aberrant IL-6 signaling and autoimmune disease : especially about rheumatoid arthritis.2003

    • Author(s)
      Hirano, T.
    • Organizer
      Senri Life Science Symposium "The frontier of immune regulation and autoimmune disease research"
    • Place of Presentation
      Senri Life Science Center, Japan.
    • Year and Date
      2003-09-02
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15002008
  • [Presentation] 免疫アレルギーとZn(亜鉛)

    • Author(s)
      平野俊夫
    • Organizer
      皮膚アレルギー・接触皮膚炎学会
    • Place of Presentation
      軽井沢プリンスホテル
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249028
  • [Presentation] The roles of IL-6 amplifier in autoimmune diseases

    • Author(s)
      平野俊夫
    • Organizer
      CREST「免疫機構」領域-CREST/さきがけ「慢性炎症」領域合同国際シンポジウム
    • Place of Presentation
      一橋記念講堂(東京)
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249028
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  • 171.  MALISSEN Bar
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