NAKAJIMA Motowo 中島元夫

… Alternative Names

中島元夫ナカジマモトオ

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Researcher Number	90240738
Affiliation (based on the past Project Information) *help	2013: 東京大学, 分子細胞生物学研究所, 客員教授 1993 – 1994: 東京大学, 分子細胞生物学研究所, 助教授 1993: 東京大学, 分子細胞生物研究所, 助教授 1992: 東京大学, 応用微生物研究所, 助教授 1992: 東大, 応微物, 助教授
Review Section/Research Field	Principal Investigator 血管生物学 Except Principal Investigator Digestive surgery
Keywords	Principal Investigator ヘパラナーゼ / ヘパラン硫酸プロテオグリカン / 基底膜 / 血管内皮細胞 / メラノーマ / 血管新生 / がん転移 / bFGF Except Principal Investigator がん転移 / 浸潤 … More / 癌転移 / 細胞増殖因子 / シグナル伝達 / サイトカイン / がん / 転移 / メタロプロテイナーゼ / TIMP / 転移遺伝子 / NM23 / 転移抑制遺伝子 / P-糖タンパク / 抗癌剤耐性 / 耐性タンパク / 耐性遺伝子 / 分子標的 / 耐性克服 / アポトーシス / モノクローナル抗体 / カルシウム拮抗剤 / ユビキチン / 細胞接着分子 / 細胞運動 / 細胞表面 / 血管新生 / 細胞外マトリックス分解酵素 / 92-kDa typeIV Collagenase / 72-kDa typeIV Collagenase / 細胞走化性因子 / 接着分子 / アミノペプチターゼ / スキャッター因子 / 癌細胞表面ムチン / 食道癌 / 肺癌 / Midkine / 11 / 食道外科学 / 分子標的治療 / がん遺伝子 / がん抑制遺伝子 / がん細胞 / DNA修復 / ヒトゲノム / 2国間共同研究 / がん遣伝子 / がん抑制遣伝子 / International Exchange Program / French-Japanese Collaborative Program in Cancer Research / German-Japanese Collaborative Program in Cancer Research / Oncogenes / Tumor Suppressor Genes / Signal Transduction / DNA Repair / Cancer Metastasis Less

Development of novel therapies targeting esophageal cancer using Midkine inhibitors
- Principal Investigator
  
  NAOMOTO YOSHIO
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kawasaki Medical School
がん転移に関与する分子とその制御機構
- Principal Investigator
  
  喜多村直美
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kansai Medical University
血管新生における血管内皮細胞基底膜ヘパラン硫酸プロテオグリカンとヘパラナーゼの役割Principal Investigator
- Principal Investigator
  
  中島元夫
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  血管生物学
- Research Institution
  The University of Tokyo
難治性癌の薬剤抵抗性の分子機構とその克服
- Principal Investigator
  
  鶴尾隆
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
がん転移に関与する分子とその制御機構
- Principal Investigator
  
  入村達郎
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokyo
がん細胞の浸潤性獲得の分子機構
- Principal Investigator
  
  清木元治
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kanazawa University
がん細胞の浸潤性獲得の分子機構
- Principal Investigator
  
  清木元治
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kanazawa University
Cooperation and information exchange with European countries.
- Principal Investigator
  
  KUROKI Toshio
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  University of Tokyo

All 2013

All Journal Article Presentation

[Journal Article] Inhibition of the growth factor MDK/midkine by a novel small molecule compound to treat non-small cell lung cancer.2013
- Author(s)
  Hao H, Maeda Y, Fukazawa T, Yamatsuji T, Takaoka M, Bao XH, Matsuoka J, Okui T, Shimo T, Takigawa N, Tomono Y, Nakajima M, Fink-Baldauf IM, Nelson S, Seibel W, Papoian R, Whitsett JA, Naomoto Y.
- Journal Title
  
  PLoS One.
  
  Volume: 16 Pages: 8-8
- DOI
  10.1371/journal.pone.0071093
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591950
[Journal Article]2013
- Author(s)
  Hao H, Maeda Y, Fukazawa T, Yamatsuji T, Takaoka M, Bao XH, Matsuoka J, Okui T, Shimo T, Takigawa N, Tomono Y, Nakajima M, Fink-Baldauf IM, Nelson S, Seibel W, Papoian R, Whitsett JA, Naomoto Y.
- Journal Title
  
  PLoS One
  
  Volume: 8(8)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591950
[Presentation] Inhibition of Midkine by a novel small molecule compound to treat non-small cell lung cancer2013
- Author(s)
  Takuya Fukazawa1, Huifang Hao1, Tomoki Yamatsuji1, Munenori Takaoka1, Nagio Takigawa2, Yutaka Maeda3, Junji Matsuoka4, Tatsuo Okui5, Tsuyoshi Shimo5, Yasuko Tomono6, Motowo Nakajima7, Jeffrey A. Whitsett2 and Yoshio Naomoto
- Organizer
  第72回日本癌学会　学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Data Source
  KAKENHI-PROJECT-23591950
[Presentation] 肺腺癌に対するMidkineを標的とした新規治療法の開発2013
- Author(s)
  深澤拓也、山辻知樹、前田豊、瀧川奈義夫、高岡宗徳、森田一郎、中島元夫、ジェフリー・ウィトセット、猶本良夫
- Organizer
  第113回日本外科学会学術集会
- Place of Presentation
  福岡県博多
- Year and Date
  2013-04-11
- Data Source
  KAKENHI-PROJECT-23591950

1. 松島網治 (50222427)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. 喜多村直実 (80107424)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 清木元治 (10154634)

# of Collaborated Projects: 2 results

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4. 木村成道 (60073029)

# of Collaborated Projects: 2 results

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5. 岡田保典 (00115221)

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6. 熊谷勝男 (00005018)

# of Collaborated Projects: 2 results

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7. NAOMOTO YOSHIO (00237190)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
8. YAMATSUJI Tomoki (40379730)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
9. FUKAZAWA Takuya (20379845)

# of Collaborated Projects: 1 results

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10. TAKAOKA Munenori (50548568)

# of Collaborated Projects: 1 results

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11. KUROKI Toshio (90006073)

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12. NIKAIDO Osamu (60019669)

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13. SEKI Shuji (50032884)

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14. TANAKA Kiyoji (80144450)

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15. HANAOKA Fumio (50012670)

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16. MAKI Hisaji (20199649)

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17. ISHIKAWA Takatoshi (30085633)

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18. SEKIGUCHI Mutsuo (00037342)

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19. 早川太郎 (80064822)

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20. 宮崎香 (70112068)

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21. 鶴尾隆 (00012667)

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22. 永沼章 (80155952)

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26. 遊佐敬介 (30200869)

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27. 入村達郎 (80092146)

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28. 宮坂昌之 (50064613)

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29. 谷口俊一郎 (60117166)

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30. 佐藤博 (00115239)

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31. 矢追義人 (20109979)

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32. 反町典子 (30217468)

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33. 繁光薫 (50585007)

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34. 許南浩 (70173573)

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35. 瀬戸加大 (80154665)

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36. 長田重一 (70114428)

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37. 相沢慎一 (60073011)

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38. 堀井明 (40249983)

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39. 広橋説雄 (70129625)

# of Collaborated Projects: 1 results

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40. 奥村康 (50009700)

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41. 勝木元也 (20051732)

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42. 山岸秀夫 (90025429)

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43. 伊藤嘉明 (80004612)

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44. 平野俊夫 (40136718)

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45. 菊谷仁 (80161412)

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46. 谷口維紹 (50133616)

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47. 豊島久真男 (90029760)

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48. 中村祐輔 (70217909)

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49. 吉田廸弘 (60001765)

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50. 大工原恭 (40028733)

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51. 貝淵弘三 (00169377)

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53. 稲垣昌樹 (30183007)

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54. 月田承一郎 (50155347)

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55. 西村暹 (20076970)

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56. 清水孝男 (80127092)

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57. HUH Nam-ho

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NAKAJIMA Motowo 中島 元夫

中島 元夫 ナカジマ モトオ

Research Projects

Research Products

Co-Researchers

Development of novel therapies targeting esophageal cancer using Midkine inhibitors

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

がん転移に関与する分子とその制御機構

Principal Investigator

Project Period (FY)

Research Category

Research Institution

血管新生における血管内皮細胞基底膜ヘパラン硫酸プロテオグリカンとヘパラナーゼの役割Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

難治性癌の薬剤抵抗性の分子機構とその克服

Principal Investigator

Project Period (FY)

Research Category

Research Institution

がん転移に関与する分子とその制御機構

Principal Investigator

Project Period (FY)

Research Category

Research Institution

がん細胞の浸潤性獲得の分子機構

Principal Investigator

Project Period (FY)

Research Category

Research Institution

がん細胞の浸潤性獲得の分子機構

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Cooperation and information exchange with European countries.

Principal Investigator

Project Period (FY)

Research Category

Research Institution

[Journal Article] Inhibition of the growth factor MDK/midkine by a novel small molecule compound to treat non-small cell lung cancer.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article]2013

Author(s)

Journal Title

Data Source

[Presentation] Inhibition of Midkine by a novel small molecule compound to treat non-small cell lung cancer2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 肺腺癌に対するMidkineを標的とした新規治療法の開発2013

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

NAKAJIMA Motowo 中島元夫

中島元夫ナカジマモトオ