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KISHIMOTO Tadamitsu  岸本 忠三

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Researcher Number 10093402
Other IDs
Affiliation (Current) 2022: 大阪大学, 免疫学フロンティア研究センター, 教授
Affiliation (based on the past Project Information) *help 2017: 大阪大学, 免疫学フロンティア研究センター, 教授
2014 – 2016: 大阪大学, 免疫学フロンティア研究センター, 特任教授
2002: 総長
2002: Osaka University, President, 総長
1999 – 2002: 大阪大学, 医学系研究科, 総長 … More
2000: 大阪大学, 総長
1997 – 1998: 大阪大学, 医学部, 総長
1997: Osaka Univ., Sch.of Med., Prof., 医学部, 教授
1991 – 1997: Professor, Osaka University, 医学部, 教授
1994: 阪大, 医学部, 教授
1986 – 1990: Division of Cellular Immunology, Institute for Molecular and Cellular Biology, O, 細胞工学センター, 教授
1986: 阪大, 国立大学(その他), 教授
1985: 大阪大学, 国立大(その他), 教授 Less
Review Section/Research Field
Principal Investigator
Biological Sciences
Except Principal Investigator
Immunology / Orthopaedic surgery / Immunology / Biological Sciences / Pathological medical chemistry / Immunology / Immunology
Keywords
Principal Investigator
サイトカイン / 自己免疫疾患 / インターロイキン6 / CD40 / IL-6 / NF-IL6 / IL-2レセプター / BSF2 / IL-5 / 急性期反応 … More / レセプター / 転写因子 / FcεRIIaとFcεRIIb / FcεRII / autoimmune disease / cytokine / receptor / signal transduction / B70 / gp130 / STAT3 / SDF-1 / HIV coreceptor / IL-6レセプター / CD23 / GPIアンカー / PIG-V / Sema4A / sema6D / TLR / MyD88非依存症性経路 / gH-gL-gO / LANA / 感染症 / 免疫病 / 自然免疫 / ヒトヘルペスウイルス6 / セマフォリン / Toll様レセプター / 粘膜免疫 / ヒトヘルペルウイルス6 / ヒトヘルペスウイルス / 腫瘍免疫 / リンフォカイン / Bリンパ球分化因子(BCDF)抗体遺伝子 / IL-2エンハンサー / NK細胞クローン / BCGF【II】 / TRF / Bリンパ球増殖因子 / IL-2 / HTLV-1(PX) / NK細胞 / プレB細胞株 / 抗体遺伝子 / 日米免疫シンポジウム / Tリンパ球レセプタ- / 主要組織適合抗原(MHC) / IgMレセプタ- / リコンビナ-ゼ / インタ-ロイキン / MF-IL-6 / The US-Japan Immunology Symposium / Major histocompatibility complex (MHC) / T cell receptor / IgM receptor / Recombinase / Interleukin / NF-IL-6 / Acute phase reaction / 自己免疫 / ミエローマ / 信号伝達 / タイロシンカイネース / MAPカイネース / ras / インタ-ロイキン6(ILー6) / ILー6レセプタ- / ILー6シグナル伝達分子(gp130) / NFーIL6 / NFーIL6β, / プラスマサイト-マ / 自己β細胞特異Tリンパ球 / インタ-ロイキン6レセプタ-(ILー6R) / シグナル伝達分子(gp130) / ILー6転写調節因子(NFーILー6) / 急性期蛋白 / ILー6トランスジェニックマウス / I型糖尿病 / plasmacytoma / インターロイキン6(ILー6) / ILー6レセプター / シグナルトランスデューサー(gp130) / ILー6トランスゲニックマウス / NFーILー6 / NODマウス / myeloma / acute phase reactions / interleukin 6 / nuclear factor / サイトカインレセプタ- / RAG1 / 抗体のプロセッシング / ス-パ-抗原 / Cytokine receptor / RAG 1 / Antigen processing / Superantigen / Autoimmune disease / リンパ球 / シグナル伝達 / 遺伝子発現 / 主要組織適合抗原 / lymphocytes / transcription factor / gene expression / autoimmune diseases / major histocompatibility antigen / 自己トレランス / アポプトーシス / CD5^+B細胞 / 接着分子 / MHC分子 / 抗原ペプチド / self-tolerance / apoptosis / CD5^+B cells / adhesion molecule / MHC molecule / antigenic peptide / ケモカインPBSF / STAT6 / ノックアウトマウス / キャッスルマン病 / リウマチ / APRF / SCIDマウス / 自己免疫病 / サイトカインシグナル伝達 / chemokine PBSF / Bリンパ球分化因子 / ミエローマ増殖因子 / Fcεレセプター / IL-6レセプターcDNA / IL-4 / BiF2 / 肝細胞刺激因子 / 抗IL6抗体 / Fcrレセプター / 抗体産生 / IFNβ2 / アトピー / EBV / Bリンパ球の増殖と分化 / Bリンパ球分因子(BCDF) / 部分アミノ酸配列 / 抗ペプチド抗体Myxoma / 活性化Bリンパ球 / Bリンパ球増殖因子(BCGF) / Two colour FACS解析 / Interleukin 6 (IL-6) / B cell stimulatory factor 2 (BSF2) / plasmacytoma growth factor / Fcepsilon receptor (FcepsilonRII) … More
Except Principal Investigator
免疫寛容 / 自己免疫疾患 / Arid5a / 免疫制御 / 免疫病 / リン酸化 / RNA結合タンパク質 / NMR / Biosensor / トランスジェニックマウス / 免疫応答 / MHC / サイトカイン / シグナル伝達 / cytokine / signal transduction / IL-6 / FasL / STAT / SSl-1 / Src / Lyn / RNA安定性制御 / osteoblast / transcription / osteoclast / cvtokine / osteoporosis / differention / RNA安定性 / ユビキチンプロテアソーム系 / NF-κB / MAPK / 転写後制御 / Immunology / interleukin-6 / mRNA Stability / トランスゲニックマウス / インターロイキン / 組みかえDNA / バイオテクノロジー / リンフォカイン / 免疫機能分子 / 自己認識 / 分裂酵母 / Cre-IoxP / 形態形成 / 高等植物 / 遺伝子標的 / 分子相互作用 / バイオセンサー / 免疫系 / ATPase / 温度感受性突然変異体 / 細胞周期 / DNA再複製 / バイオモニタリング / RNAプロセシング / 遺伝子ターゲティング / 蛋白高次機能構造 / 胚形成 / 植物 / Fission yeast / Cre-loxP / Morphogenesis / Higher plants / Gene targeting / Protein interaction / 総括班 / 情報提供 / 情報交換 / 国際シンポジウム / ジーンノックアウトマウス / immune regulation / immune tolerance / group of generalization / providing information / information exchanges / international symposium / transgenic mouse / gene knockout mouse / T細胞 / B細胞 / 発生工学 / ポリコ-ム遺伝子 / 水晶体特異的遺伝子発現 / 有機リン系農薬センサー / 転写因子 / T cell / Immunological tolerance / B cell / Transgenics / Polycomb genes / Crystallin gene / Transcriptional factor / CD40, CD40L / CD80, CD86 / HSI / CD95L / TCR / TGF-β / Smad / CD40 / アポトーシス / TCR-peptides / CD40-CD40L / TGF-beta / 抗原受容体 / 補助受容体 / 細胞分化 / 炎症疾患 / 免疫異常 / ノックアウトマウス / immune response / antigen receptor / co-receptor / cell differentiation / autoimmune disease / inflammation / 軟骨由来因子 / 軟骨由来抗腫瘍因子 / 線維芽細胞由来内皮細胞増殖因子 / エリスロポエチン様因子 / インスリン作用促進因子 / 血小板由来増殖阻害因子 / 腫瘍増殖促進因子 / Bリンパ球分化因子 / Cartilage-Derived Factor (CDF) / Cartilage-derived Anti-Tumor Factor (CATF) / Fibroblast-derived Endothelial Cell Growth Factor (f-ECGF) / Erythropoietin-like factor / Insulin-Stimulating Peptide (ISP) / Platelet-Derived Growth Inhibitor (PDGI) / Tumor Growth Stimulating Activity (TGSA) / Immune Regulation / Phosphorylation / Degradation / Ubiquitination / p38 MAPK / ユビキチン化 / タンパク質分解 / T細胞過剰活性化 / 転写後調節 / IL-6 mRNA / STAT分子 / Th17細胞 / Regnase-1 / インフルエンザ / 感染・炎症 / サイトカインストーム Less
  • Research Projects

    (25 results)
  • Research Products

    (7 results)
  • Co-Researchers

    (148 People)
  •  MAPKシグナルに関連したArid5aタンパク質分解機構の解明Host Researcher

    • Host Researcher
      岸本 忠三
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for JSPS Fellows
    • Research Field
      Immunology
    • Research Institution
      Osaka University
  •  The pathogenic role of Arid5a in infection and autoimmunity.

    • Principal Investigator
      MASUDA Kazuya
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Immunology
    • Research Institution
      Osaka University
  •  免疫細胞および自己免疫疾患のIL-6 mRNA調節におけるArid5aの役割Host Researcher

    • Host Researcher
      岸本 忠三
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for JSPS Fellows
    • Research Field
      Immunology
    • Research Institution
      Osaka University
  •  Regulatory mechanism of signal transduction in the immune system.

    • Principal Investigator
      HIRANO Toshio
    • Project Period (FY)
      1999 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  感染症と免疫病の分子生物学と医学Principal Investigator

    • Principal Investigator
      山西 弘一, 岸本 忠三
    • Project Period (FY)
      1997 – 2003
    • Research Category
      Grant-in-Aid for COE Research
    • Research Institution
      Osaka University
  •  Immune regulation and signal tranduction

    • Principal Investigator
      OKUMURA Ko
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      Immunology
    • Research Institution
      Juntendo University School of Medicine
  •  Regulation of Gene Expression

    • Principal Investigator
      TANIGUCHI Masaru
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Chiba University, School of Medicine
  •  Immune regulation and signal tranduction

    • Principal Investigator
      OKUMURA Ko
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Juntendo University School of Medicine
  •  骨粗鬆症の基礎に関する分子機構の研究動向の調査

    • Principal Investigator
      野田 政樹
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Tokyo Medical and Dental University
  •  Regulation of Gene Expression

    • Principal Investigator
      TANIGUCHI Masaru
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Chiba University
  •  Studies on molecular mechanisms of autoimmune diseasesPrincipal Investigator

    • Principal Investigator
      KISHIMOTO Tadamitsu
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Osaka University
  •  免疫病の分子・遺伝子治療に関する研究Principal Investigator

    • Principal Investigator
      KISHIMOTO Tadamitsu
    • Project Period (FY)
      1993 – 1996
    • Research Category
      Grant-in-Aid for Specially Promoted Research
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  Molecular mechanism of immune regulation and immune tolerance

    • Principal Investigator
      SASAZUKI Takehiko
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University
  •  免疫制御・寛容の分子機構

    • Principal Investigator
      SASAZUKI Takehiko
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Institution
      Kyushu University
  •  Studies on the regulation of gene expression in lymphoid cells.Principal Investigator

    • Principal Investigator
      KISHIMOTO Tadamitsu
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Osaka University
  •  Studies on the regulation of gene expression in lymphoid cells.Principal Investigator

    • Principal Investigator
      KISHIMOTO Tadamitsu
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Osaka University
  •  Exchange of the informations in the cooperative immunology research between the US-Japan Bords.Principal Investigator

    • Principal Investigator
      KISHIMOTO Tadamitsu
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Overseas Scientific Survey.
    • Research Institution
      Institute for Molecular and Cellular Biology, Osaka University
  •  Studies on molecular regulation of the immune systemPrincipal Investigator

    • Principal Investigator
      KISHIMOTO Tadamitsu
    • Project Period (FY)
      1989 – 1992
    • Research Category
      Grant-in-Aid for Specially Promoted Research
    • Research Institution
      Osaka University
  •  生命科学技術の進展への象疫学の対応

    • Principal Investigator
      奥村 康
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Immunology
    • Research Institution
      Juntendo University
  •  米国西海岸地域における分子免疫生物学の進捗に関する調査研究Principal Investigator

    • Principal Investigator
      岸本 忠三
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Overseas Scientific Research
  •  リンフォカインとそのアクセプターに関する免疫学的及び分子生物学的研究Principal Investigator

    • Principal Investigator
      岸本 忠三
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Osaka University
  •  生命科学技術の進展への免疫学の対応

    • Principal Investigator
      多田 富雄
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Immunology
    • Research Institution
      The University of Tokyo
  •  リンフォカインとそのアクセプターに関する免疫学的及び分子生物学的研究Principal Investigator

    • Principal Investigator
      岸本 忠三
    • Project Period (FY)
      1985
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Osaka University
  •  Bリンパ球増殖・分化機構の解明とその異常制御に関する研究Principal Investigator

    • Principal Investigator
      KISHIMOTO Tadamitsu
    • Project Period (FY)
      1985 – 1988
    • Research Category
      Grant-in-Aid for Specially Promoted Research
    • Research Institution
      Institute for Molecular and Cellular Biology, Osaka University
  •  Reaction mechanisms of various growth regulators and differentiation regulators and their clinical applications

    • Principal Investigator
      SUZUKI Fujio
    • Project Period (FY)
      1984 – 1986
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Osaka University

All 2017 2016 2015

All Journal Article Presentation Patent

  • [Journal Article] Arid5a-deficient mice are highly resistant to bleomycin-induced lung injury.2017

    • Author(s)
      Dubey PK, Masuda K, Nyati KK, Zaman MM, Chalise JP, Millrine D, Kai W, Ripley B, Kishimoto T.
    • Journal Title

      Int. Immunol.

      Volume: 29 Pages: 79-85

    • DOI

      10.1093/intimm/dxx004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15F15907
  • [Journal Article] TLR4-induced NF-κB and MAPK signaling regulate the IL-6 mRNA stabilizing protein Arid5a.2017

    • Author(s)
      Nyati KK, Masuda K, Zaman MM, Dubey PK, Millrine D, Chalise JP, Higa M, Li S, Standley DM, Saito K, Hanieh H, Kishimoto T.
    • Journal Title

      Nucleic Acids Res.

      Volume: 45 Pages: 2687-2703

    • DOI

      10.1093/nar/gkx064

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15F15907, KAKENHI-PROJECT-16K19155
  • [Journal Article] Arid5a regulates naïve CD4+ T-cell fate through selective stabilization of Stat3 mRNA2016

    • Author(s)
      Masuda, K., Ripley, B., Nyati, K., Dubey, P., Zaman, M., Hanieh, H., Hoga, M., Yamashita, K., Standley, D., Mashima, T., Katahira, M., Okamoto, T., Matsuura, Y., Takeuchi, O. and Kishimoto, T.
    • Journal Title

      the Journal of Experimental Medicine

      Volume: 213 Pages: 605619-605619

    • DOI

      10.1084/jem.20151289

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PUBLICLY-15H00813, KAKENHI-PROJECT-26840020, KAKENHI-PROJECT-26860328, KAKENHI-PROJECT-15H04736
  • [Journal Article] Arid5a exacerbates IFN-γ-mediated septic shock by stabilizing T-bet mRNA2016

    • Author(s)
      Zaman MM, Masuda K, Nyati KK, Dubey PK, Ripley B, Wang K, Chalise JP, Higa M, Hanieh H, Kishimoto T.
    • Journal Title

      Proc Natl Acad Sci U S A.

      Volume: 113 Pages: 11543-11548

    • DOI

      10.1073/pnas.1613307113

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15F15907, KAKENHI-PROJECT-16K19155
  • [Patent] 新規な敗血症治療剤及び/又はそのスクリーニング方法2015

    • Inventor(s)
      岸本忠三、増田和哉、中外製薬
    • Industrial Property Rights Holder
      岸本忠三、増田和哉、中外製薬
    • Industrial Property Rights Type
      特許
    • Filing Date
      2015-04-16
    • Overseas
    • Data Source
      KAKENHI-PROJECT-26860328
  • [Patent] 新規な肺疾患治療剤及び/又はそのスクリーニング方法2015

    • Inventor(s)
      岸本忠三、増田和哉、中外製薬
    • Industrial Property Rights Holder
      岸本忠三、増田和哉、中外製薬
    • Industrial Property Rights Type
      特許
    • Filing Date
      2015-06-30
    • Overseas
    • Data Source
      KAKENHI-PROJECT-26860328
  • [Presentation] T-cell intrinsic role of Arid5a as a stability protein of Stat3 mRNA in an IL-6-dependent manner2015

    • Author(s)
      Kazuya Masuda, Barry Ripley, Kishan Kumar Nyati, Praveen Kumar Dubey, Mohammad Mahabub-Uz Zaman and Tadamitsu Kishimoto
    • Organizer
      The 44th Annual Meeting of The Japanese society for Immunology
    • Place of Presentation
      札幌
    • Year and Date
      2015-11-18
    • Data Source
      KAKENHI-PROJECT-26860328
  • 1.  SASAZUKI Takehiko (50014121)
    # of Collaborated Projects: 13 results
    # of Collaborated Products: 0 results
  • 2.  OKUMURA Ko (50009700)
    # of Collaborated Projects: 12 results
    # of Collaborated Products: 0 results
  • 3.  HONJO Tasuku (80090504)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 0 results
  • 4.  HIRANO Tosio (40136718)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 5.  WATANABE Takeshi (40028684)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 6.  KIKUTANI Hitoshi (80161412)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 7.  TANIGUCHI Masaru (80110310)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 8.  TANIGUCHI Tadatsugu (50133616)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 9.  TAKATSU Kiyoshi (10107055)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 10.  多田 富雄 (10009136)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 11.  NISHIKAWA Shinichi (60127115)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 12.  AKIRA Shizuo (50192919)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 13.  SUGAMURA Kazuo (20117360)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 14.  NYATI Kishan Kumar
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 6 results
  • 15.  YASUDA Kunio (30025473)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 16.  SAKAGUCHI Nobuo (70192086)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 17.  TAGA Tetsuya (40192629)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 18.  KAMADA Hiroshi (00169608)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 19.  SHIMADA Kazuo (70196476)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 20.  HORINOUCHI Sueharu (80143410)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 21.  SHIMURA Yoshiro (60025426)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 22.  YAMADA Yasuyuki (50026415)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 23.  KARUBE Isao (50089827)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 24.  BEPPU Teruhiko (80011873)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 25.  KOSEKI Haruhiko (40225446)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 26.  SAITO Takashi (50205655)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 27.  山西 弘一 (10029811)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 28.  木下 タロウ (10153165)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 29.  清野 宏 (10271032)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 30.  浜岡 利之 (60028529)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 31.  TAKEMORI Toshitada (60114295)
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  • 143.  HERZENBERG L
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  • 146.  OKAMOTO Toru
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  • 147.  真嶋 司
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  • 148.  松浦 善治
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