SAKAGUCHI NOBUO 阪口薫雄

… Alternative Names

SAKAGUCHI Nobuo 坂口薫雄

Less

Researcher Number	70192086
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2015: 熊本大学, 生命科学研究部, 教授 2014: 熊本大学, 大学院生命科学研究部, 教授 2013: 熊本大学, 生命科学研究部, 教授 2012: 熊本大学, 大学院生命科学研究部, 教授 2009 – 2011: Kumamoto University, 大学院・生命科学研究部, 教授 … More 2007 – 2008: Kumamoto University, 大学院・医学薬学研究部, 教授 2004 – 2006: Kumamoto University, Graduate School of Medical Sciences, Professor, 大学院医学薬学研究部, 教授 2003 – 2004: 熊本大学, 大学院・医学薬学研究部, 教授 1995 – 2003: 熊本大学, 医学部, 教授 1992 – 1995: Tottori University, Faculty of Medicine Department of Immunology, Professor, 医学部, 教授 1988 – 1991: 佐賀医科大学, 医学部, 助教授 1989: Saga Medical School, 助教授 Less
Review Section/Research Field	Principal Investigator Biological Sciences / Immunology / Immunology / Immunology Except Principal Investigator Biological Sciences / General pharmacology
Keywords	Principal Investigator シグナル伝達 / MB-1 / B細胞 / 胚中心 / 抗原レセプター / ラパマイシン / 免疫抑制剤 / B細胞活性化 / signal transduction / 免疫学 … More / 遺伝子 / mTor / rapamycin / 抗体産生 / トレランス / アポトーシス / リン酸化 / B細胞cDNAライブラリー / Iga / pre-B cell / pre-B細胞 / ホジキン病 / 生体分子 / 細胞・組織 / プライマーゼ / RNA輸送 / ノックアウトマウス / S6キナーゼ / T細胞依存性抗原 / 細胞増殖 / タンパク質脱リン酸化 / ホスファターゼ / 細胞周期 / ストレス / preーB細胞 / モノクロ-ナル抗体 / IgMレセプタ- / B細胞特異的遺伝子 / Bリンパ腫特異的遺伝子 / RNA免疫沈降 / リンパ腫 / 翻訳 / 転写 / Affinity of antibody / Germinal Center / DNA replication / Oncogenesis / B lymphoma / ウイルス感染 / ウイルス感線 / 体細胞突然変異 / DNA修復 / 抗体親和性 / DNA複製 / 発ガン / Bリンパ腫 / gene knock out mice / B cell antigen receptor / protein synthesis pathway / S6 kinase / 抗体レパートリー / B細胞異常 / モノクロナール抗体 / セントロサイト / CD40 / B細胞抗原レセプター / タンパク質合成誘導 / phosphatase / 胎児 / 細胞分化 / α4 / Igα(MB-1) / PP2A / 増殖 / α4分子 / Apoptosis / Antigen receptor / B cell / MB‐1 / phosphorylation / monoclonal Ab / IgM receptor / pre B細胞 / lgMレセプター / モノクローナル抗体 / IgMレセプター / RNA / 感染 / ゲノム / 感染症 / 悪性黒色腫 / がん抑制分子 / 病理診断 / 転移 / 細胞 / 癌 / 乳癌 / 老化 / 発がん / 胸腺 / T細胞 / 生体防御 / 液性免疫反応 / 遺伝子改変マウス / クラススイッチ / TOR / 液性免疫 / 脳神経 / ラバマイシン / B細胞レセプター / lgR結分分子 / B細胞レセプタ- / Ca^<2+>動員 / cDNAクロ-ニング / B細胞cDNAライブラリ- / Ig結合タンパク / トランスメンフランシブナリング … More Except Principal Investigator 免疫寛容 / IL-6 / シグナル伝達 / NFκB / ADAP / IRAK-4 / T cell / T細胞 / signal transduction / IL-5 / GANP / 転写因子 / ゲノム創薬 / ELISA実験 / 新型診断薬の開発 / 虚血性心疾患 / モノクローナル抗体 / 国際研究情報交換 / 国際研究者交流 / マウス心筋梗塞モデル / ヒト血中TNNI3K 濃度 / マウス血中TNNI3K 濃度 / モノクローナル抗体作成 / 創薬ゲノム薬理学 / 心筋損傷診断マーカー / 心筋梗塞 / 急性心筋虚血 / 金コロイドー銀増幅法 / ELISA法 / 血中TNNI3K濃度 / 血中濃度 / 創薬 / ELISA / 心疾患 / ゲノム薬理学 / 心筋虚血 / 金コロイド銀増幅型検査チップ / TNNI3K / immunological synapse / Immunology / 樹状細胞 / 高親和性抗体 / PILR / ペア型レセブター / アクチン再構成 / 細胞分裂 / キラーT細胞 / 制御性T細胞 / CTLA-4 / lipid raft / シグナルクロストーク / 獲得免疫系 / 自然免疫系 / ラフト / T細胞活性化 / NF_κB / 免疫シナプス / 免疫学 / Transcriptional factor / Biosensor / Crystallin gene / Polycomb genes / Transgenics / B cell / Immunological tolerance / 有機リン系農薬センサー / 水晶体特異的遺伝子発現 / ポリコ-ム遺伝子 / 発生工学 / B細胞 / costimulatory factor / apoptosis / cytokine / antigen receptor / tolerance / lymphocyte lineage / クローナル除去 / リンパ球初期分化 / 補助因子受容体 / サイトカイン受容体 / 骨髄ストローマ / 補助刺激因子 / 細胞死 / サイトカイン / 抗原受容体 / リンパ球増殖分化 / Acute phase reaction / NF-IL-6 / Interleukin / Recombinase / IgM receptor / T cell receptor / Major histocompatibility complex (MHC) / The US-Japan Immunology Symposium / 急性期反応 / MF-IL-6 / インタ-ロイキン / リコンビナ-ゼ / IgMレセプタ- / 主要組織適合抗原(MHC) / Tリンパ球レセプタ- / 日米免疫シンポジウム / MCM3 / α4 / PI-3K / c-Rel / PLC-γ2 / BCAP / BLNK / BCR / 胸腺外分化 / Bリンパ球 / Tリンパ球 / コミットメント / GTPase活性化蛋白 / クローン増巾 / アナ-ジ- / 免疫応答 / 細胞骨格 / 細胞接着 / Ras / Rap1 / 低分子G蛋白 / 遺伝子組み換え / 細胞分化 / 胚中心 / インテグリン / 低分子量G蛋白 / レパートリー形成 / 抗原レセプター Less

Circulating TNNI3K levels are useful diagnosis biomarker for ischemic myocardial diseases
- Principal Investigator
  
  Yorinaka (Lai) Hoichi (Zhong-Fang)
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Kumamoto University
リンパ細胞のＲＮＡ輸送からタンパク質翻訳に至る選択的調節機構の解析Principal Investigator
- Principal Investigator
  
  阪口薫雄
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Immunology
- Research Institution
  Kumamoto University
Regulation of HIV-1 restriction factor Apobec3G by mRNA export factorPrincipal Investigator
- Principal Investigator
  
  SAKAGUCHI NOBUO
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Immunology
- Research Institution
  Kumamoto University
Molecular mechanism of the selective AID targeting at the IgV-regionPrincipal Investigator
- Principal Investigator
  
  SAKAGUCHI NOBUO
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  Kumamoto University
Lyn信号伝達における高親和性B細胞選択の分子信号Principal Investigator
- Principal Investigator
  
  阪口薫雄
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kumamoto University
Role of the RNA-primase GANP in cancer developmentPrincipal Investigator
- Principal Investigator
  
  SAKAGUCHI Nobuo
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kumamoto University
An experimental mouse model of spontaneous generation of HodgkinDisease by introduction of GANP RNA-primase genePrincipal Investigator
- Principal Investigator
  
  SAKAGUCHI Nobuo
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kumamoto University
Acquisition of Signal Information for Immune Surveillance and Determination of Immune Responses
- Principal Investigator
  
  SAITO Takashi
- Project Period (FY)
  2003 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  RIKEN
  Chiba University
S6キナーゼ活性制御分子α4の機能と治療への解析Principal Investigator
- Principal Investigator
  
  阪口薫雄
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kumamoto University
細胞抗原レセプターシグナル伝達分子α4からのS6キナーゼ活性化誘導の研究Principal Investigator
- Principal Investigator
  
  阪口薫雄
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kumamoto University
B細胞の抗原認識と活性化制御
- Principal Investigator
  
  黒崎知博
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kansai Medical University
細胞抗原レセプターシグナル伝達分子α4からのS6キナーゼ活性化誘導の研究Principal Investigator
- Principal Investigator
  
  阪口薫雄
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kumamoto University
レパートリー形成の分子機構
- Principal Investigator
  
  湊長博
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyoto University
B細胞抗原レセプター結合分子α4分子の蛋白フォスファターゼ制御シグナル経路の解析Principal Investigator
- Principal Investigator
  
  阪口薫雄
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kumamoto University
Study of B cell antigen receptor (BCR)-mediated signal transduction pathwayPrincipal Investigator
- Principal Investigator
  
  SAKAGUCHI Nobuo
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  Kumamoto University
Regulation of Gene Expression
- Principal Investigator
  
  TANIGUCHI Masaru
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Chiba University, School of Medicine
Analysis of immature B cell activation and differentiationPrincipal Investigator
- Principal Investigator
  
  SAKAGUCHI Nobuo
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  KUMAMOTO UNIVERSITY
  Tottori University
B細胞のシグナル伝達Principal Investigator
- Principal Investigator
  
  阪口薫雄
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kumamoto University
  Tottori University
Molecular mechnisms of immune tolerance.
- Principal Investigator
  
  HIRANO Toshio
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
Expression and function of B cell specific MB-1 protein associated with IgM receptorPrincipal Investigator
- Principal Investigator
  
  SAKAGUCHI Nobuo
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  Tottori University
B細胞シグナル伝達機構の解析Principal Investigator
- Principal Investigator
  
  阪口薫雄
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tottori University
B細胞シグナル伝達機構の解析Principal Investigator
- Principal Investigator
  
  阪口薫雄
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  佐賀医科大学
B細胞シグナル伝達機構の構造解析Principal Investigator
- Principal Investigator
  
  阪口薫雄
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  佐賀医科大学
Expression and function of B cell specific MB-1 protein associated with IgM receptorPrincipal Investigator
- Principal Investigator
  
  SAKAGUCHI Nobuo
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  Tottori University
  佐賀医科大学
Bリンパ腫瘍細胞特異的に発現する遺伝子クローンの解析Principal Investigator
- Principal Investigator
  
  阪口薫雄
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  佐賀医科大学
B細胞特異的遺伝子mb-1の構造、機能の解析Principal Investigator
- Principal Investigator
  
  阪口薫雄
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  佐賀医科大学
Exchange of the informations in the cooperative immunology research between the US-Japan Bords.
- Principal Investigator
  
  KISHIMOTO Tadamitsu
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Overseas Scientific Survey.
- Research Institution
  Institute for Molecular and Cellular Biology, Osaka University
Bリンパ腫瘍細胞特異的に発現する遺伝子クローンの解析Principal Investigator
- Principal Investigator
  
  阪口薫雄
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  佐賀医科大学
B細胞特異的遺伝子の解析Principal Investigator
- Principal Investigator
  
  阪口薫雄
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  佐賀医科大学

All 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Book Patent

[Book] 臨床免疫・アレルギー科, 免疫グロブリンの体細胞高頻度突然変異誘導と GANP2014
- Author(s)
  下田真唯子, 前田和彦, 阪口薫雄
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-23390122
[Book] 免疫グロブリンの体細胞高頻度突然変異誘導とGANP、臨床免疫・アレルギー科(61(5))2014
- Author(s)
  下田真唯子、前田和彦、阪口薫雄
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-24659224
[Book] 胚中心B細胞の高親和性成熟におけるGANPの役割2013
- Author(s)
  前田和彦、阪口薫雄
- Publisher
  臨床免疫・アレルギー科　科学評論社
- Data Source
  KAKENHI-PROJECT-24659224
[Book] 胚中心B細胞の高親和性成熟におけるGANPの役割、臨床免疫・アレルギー科(60(2))2013
- Author(s)
  前田和彦、阪口薫雄
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-24659224
[Book] 胚中心B細胞の高親和性成熟におけるGANPの役割2013
- Author(s)
  前田和彦、阪口薫雄
- Publisher
  臨床免疫・アレルギー科　科学評論社
- Data Source
  KAKENHI-PROJECT-23390122
[Book] 臨床免疫・アレルギー科, 胚中心B細胞の高親和性成熟における GANP の役割2013
- Author(s)
  前田和彦, 阪口薫雄
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-23390122
[Book] 臨床免疫・アレルギー科, プロテインホスファターゼ 2A の調節と自己免疫2012
- Author(s)
  前田和彦, 阪口薫雄
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-23390122
[Book] 臨床免疫・アレルギー科, B細胞の生存維持とmiRNA2012
- Author(s)
  前田和彦, 阪口薫雄
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-23390122
[Book] 免疫学コア講義改訂3版、編集、第6章、第9章、付表12012
- Author(s)
  阪口薫雄、前田和彦
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-24659224
[Book] 免疫学コア講義改訂3版2012
- Author(s)
  阪口薫雄, 前田和彦
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-23390122
[Book] B細胞の生存維持とmiRNA、臨床免疫・アレルギー科(58(3))2012
- Author(s)
  前田和彦、阪口薫雄
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-24659224
[Book] 自己免疫疾患とB1細胞、臨床免疫・アレルギー科(57(2))2012
- Author(s)
  北畠正大、阪口薫雄
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-24659224
[Book] プロテインホスファターゼ2Aの調節と自己免疫、臨床免疫・アレルギー科(57(2))2012
- Author(s)
  前田和彦、阪口薫雄
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-24659224
[Book] 加齢とreceptor editing機能2011
- Author(s)
  戸田哲平, 阪口薫雄
- Publisher
  科学評論社
- Data Source
  KAKENHI-PUBLICLY-22021036
[Book] 臨床免疫・アレルギー科, 胚中心B細胞の分化・増殖と GANP2011
- Author(s)
  前田和彦, 阪口薫雄
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-23390122
[Book] 免疫記憶の制御と疾患/B 細胞免疫記憶:免疫記憶研究のフロンティア, 実験医学, 高親和性抗体産生のメカニズム2011
- Author(s)
  前田和彦, 阪口薫雄
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-23390122
[Book] 第6章翻訳2010
- Author(s)
  阪口薫雄
- Publisher
  メディカル・サイエンス・インターナショナル
- Data Source
  KAKENHI-PUBLICLY-22021036
[Book] B細胞のreceptor editingと自己免疫疾患2010
- Author(s)
  戸田哲平, 阪口薫雄
- Publisher
  科学評論社
- Data Source
  KAKENHI-PUBLICLY-22021036
[Book] 抗体の抗原親和性成熟とGANPの役割2010
- Author(s)
  前田和彦, 阪口薫雄
- Publisher
  科学評論社
- Data Source
  KAKENHI-PUBLICLY-22021036
[Journal Article] JNK Regulatory Molecule G5PR Induces IgG Autoantibody-Producing Plasmablasts from Peritoneal B1a Cells.2015
- Author(s)
  Kitabatake M, Soma M, Zhang T, Kuwahara K, Fukushima Y, Nojima T, Kitamura D, Sakaguchi N.
- Journal Title
  
  J Immunol.
  
  Volume: 194 Issue: 4 Pages: 1480-1488
- DOI
  10.4049/jimmunol.1401127
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-24111001, KAKENHI-PROJECT-24590388, KAKENHI-PUBLICLY-25111512, KAKENHI-PUBLICLY-25118730, KAKENHI-PROJECT-25293116, KAKENHI-PROJECT-25460337, KAKENHI-PROJECT-25860813, KAKENHI-PROJECT-26670239, KAKENHI-PROJECT-15K10083
[Journal Article] Pcid2 inactivates developmental genes in human and mouse embryonic stem cells to sustain their pluripotency by modulation of EID1 stability2014
- Author(s)
  Ye B, Dai Z, Liu B, Wang R, Li C, Huang G, Wang S, Xia P, Yang X, Kuwahara K, Sakaguchi N, Fan Z
- Journal Title
  
  Stem Cells
  
  Volume: 32 Issue: 3 Pages: 623-635
- DOI
  10.1002/stem.1580
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390122, KAKENHI-PROJECT-24659224
[Journal Article] Infection of adult thymus with murine retrovirus induces virus-specific central tolerance that prevents functional memory CD8+ T cell differentiation2014
- Author(s)
  Takamura S, Kajiwara E, Tsuji-Kawahara S, Masumoto T, Fujisawa M, Kato M, Chikaishi T, Kawasaki Y, Kinoshita S, Itoi M, Sakaguchi N, Miyazawa M
- Journal Title
  
  PLoS Pathog
  
  Volume: 10 Issue: 3 Pages: e1003937-e1003937
- DOI
  10.1371/journal.ppat.1003937
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390122, KAKENHI-PROJECT-24390116, KAKENHI-PROJECT-24659224, KAKENHI-PROJECT-24689043, KAKENHI-PROJECT-25460507
[Journal Article] GANP regulates the choice of DNA repair pathway by DNA-PKcs interaction in AID-dependent IgV region diversification2014
- Author(s)
  Eid MMA, Maeda K, Almofty SA, Singh SK, Shimoda M, Sakaguchi N.
- Journal Title
  
  The Journal of Immunology
  
  Volume: 192(印刷中) Issue: 12 Pages: 5529-5539
- DOI
  10.4049/jimmunol.1400021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13F03407, KAKENHI-PROJECT-23390122, KAKENHI-PROJECT-24659224, KAKENHI-PROJECT-26460580
[Journal Article] Histopathological evaluation of the diversity of cells susceptible to H5N1 virulent avian influenza virus2013
- Author(s)
  Ogiwara H, Yasui F, Munekata K, Takagi-Kamiya A, Munakata T, Nomura N, Shibasaki F, Kuwahara K, Sakaguchi N, Sakoda Y, Kida H, Kohara M
- Journal Title
  
  Am. J. Pathol
  
  Volume: 184 Issue: 1 Pages: 171-183
- DOI
  10.1016/j.ajpath.2013.10.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23390122, KAKENHI-PROJECT-23659314, KAKENHI-PROJECT-24590388, KAKENHI-PROJECT-24590565, KAKENHI-PROJECT-24659224, KAKENHI-PROJECT-25670224, KAKENHI-PROJECT-25670281
[Journal Article] GANP regulates recruitment ofAID to immunoglobulin variable regions bymodulating transcription and nucleosomeoccupancy2013
- Author(s)
  Shailendra Kumar Singh, Kazuhiko Maeda(co-first author), Mohammed Mansour AbbasEid, Sarah Ameen Almofty, Masaya Ono,Phuong Pham, Myron F. Goodman, and NobuoSakaguchi
- Journal Title
  
  Nat. Commun
  
  Volume: 4 Issue: 1 Pages: 1830-1830
- DOI
  10.1038/ncomms2823
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590436, KAKENHI-PROJECT-23390122, KAKENHI-PROJECT-24659224
[Journal Article] Breast cancers with high DSS1 expression that potentially maintains BRCA2 stability have poor prognosis in the relapse-free survival2013
- Author(s)
  Rezano A, Kuwahara K, Yamamoto-Ibusuki M, Kitabatake M, Moolthiya P, Phimsen S, Suda T, Tone S, Yamamoto Y, Iwase H, Sakaguchi N
- Journal Title
  
  BMC Cancer
  
  Volume: 13 Issue: 1 Pages: 562-562
- DOI
  10.1186/1471-2407-13-562
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390122, KAKENHI-PROJECT-23570083, KAKENHI-PROJECT-24590388, KAKENHI-PROJECT-24659224, KAKENHI-PROJECT-25860813
[Journal Article] CA-S27 : a novel Lewis a associated carbohydrate epitope is diagnostic and prognostic for cholangiocarcinoma2013
- Author(s)
  Silsirivanit A, Araki N, Wongkham C, Vaeteewoottacharn K, Pairojkul C, Kuwahara K, Narimatsu Y, Sawaki H, Narimatsu H, Okada S, Sakaguchi N, Wongkham S
- Journal Title
  
  Cancer Sci
  
  Volume: 104 Issue: 10 Pages: 1278-1284
- DOI
  10.1111/cas.12222
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390122, KAKENHI-PROJECT-24590388, KAKENHI-PROJECT-24659224, KAKENHI-PROJECT-25293312, KAKENHI-PROJECT-25640068
[Journal Article] GANP interacts with APOBEC3G and facilitates its encapsidation into the virions to reduce HIV-1 infectivity2013
- Author(s)
  Maeda K, Almofty SA (co-first author), Singh SK, Eid MMA, Shimoda M, Ikeda T, Koito A, Pham P, Goodman MF, Sakaguchi N
- Journal Title
  
  J. Immunol
  
  Volume: 191 Issue: 12 Pages: 6030-6039
- DOI
  10.4049/jimmunol.1302057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390122, KAKENHI-PROJECT-23590546, KAKENHI-PROJECT-24659224
[Journal Article] Broad-spectrum detection of h5 subtype influenza a viruses with a new fluorescent immunochromatography system2013
- Author(s)
  Sakurai A, Takayama K, Nomura N, Munakata T, Yamamoto N, Tamura T, Yamada J, Hashimoto M, Kuwahara K, Sakoda Y, Suda Y, Kobayashi Y, Sakaguchi N, Kida H, Kohara M, Shibasaki F
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 11 Pages: e76753-e76753
- DOI
  10.1371/journal.pone.0076753
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390122, KAKENHI-PROJECT-23659069, KAKENHI-PROJECT-23659314, KAKENHI-PROJECT-24590388, KAKENHI-PROJECT-24590565, KAKENHI-PROJECT-24659224, KAKENHI-PROJECT-25670224, KAKENHI-PROJECT-25670281, KAKENHI-PROJECT-25860420
[Journal Article] GANP interacts with APOBEC3G and facilitates its encapsidation into the virions to reduce HIV-1 infectivity.2013
- Author(s)
  Maeda K, Almofty SA, Singh SA, Eid MMA, Shimoda M, Ikeda T, Koito A, Pham P, Goodman MF, Sakaguchi N.
- Journal Title
  
  The Journal of Immunology
  
  Volume: 191 Pages: 6030-6039
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13F03407
[Journal Article] Lyn signaling to upregulate GANP is critical for the survival of high-affinity B cells in germinal centers of lymphoid organs2012
- Author(s)
  Kuwahara K, Nakaya T, Phimsen S, Toda T, Kitabatake M, Kaji T, Takemori T, Watanabe T, Sakaguchi N
- Journal Title
  
  J. Immunol
  
  Volume: 189 Issue: 7 Pages: 3472-3479
- DOI
  10.4049/jimmunol.1200649
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390122, KAKENHI-PROJECT-23791116, KAKENHI-PROJECT-24659224
[Journal Article] Selective cell death of p53-insufficient cancer cells is induced by knockdown of the mRNA export molecule GANP2012
- Author(s)
  Phimsen S, et al
- Journal Title
  
  Apoptosis
  
  Volume: (印刷中) Issue: 7 Pages: 679-690
- DOI
  10.1007/s10495-012-0711-8
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021036, KAKENHI-PROJECT-23390122, KAKENHI-PROJECT-23570083, KAKENHI-PROJECT-23791116, KAKENHI-PROJECT-24590388
[Journal Article] Dynamic appearance of antigenic epitopes effective for viral neutralization during membrane fusion initiated by interactions between HIV-1 envelope proteins and CD4/CXCR42012
- Author(s)
  Toda T, et al
- Journal Title
  
  Immunobiology
  
  Volume: (印刷中) Issue: 9 Pages: 864-872
- DOI
  10.1016/j.imbio.2011.12.007
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021036, KAKENHI-PROJECT-22590436, KAKENHI-PROJECT-23390122, KAKENHI-PROJECT-23590548, KAKENHI-PROJECT-24590388
[Journal Article] Transgenic overexpression of G5PR that is normally augmented in centrocytes impairsthe enrichment of high-affinity antigen-specific B cells, increases peritoneal B-1a cells, and induces autoimmunity in aged female mice2012
- Author(s)
  hi H, Ohtsuji M, Tsurui H, Hirose S, and Sakaguchi N
- Journal Title
  
  J. Immunol
  
  Volume: 189 Issue: 3 Pages: 1193-1201
- DOI
  10.4049/jimmunol.1102774
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590194, KAKENHI-PROJECT-23390122, KAKENHI-PROJECT-23791116, KAKENHI-PROJECT-24590491, KAKENHI-PROJECT-24659224
[Journal Article] Molecular Mechanism of Immunoglobulin V-Region Diversification Regulated by Transcription and RNA Metabolism in Antigen-Driven B Cells2011
- Author(s)
  Sakaguchi N, et al
- Journal Title
  
  Scandinavian Journal of Immunology
  
  Volume: 73 Issue: 6 Pages: 520-526
- DOI
  10.1111/j.1365-3083.2011.02557.x
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021036, KAKENHI-PROJECT-22590436, KAKENHI-PROJECT-23390122
[Journal Article] Molecular Mechanism of Immunoglobulin V-Region Diversification Regulated by Transcription and RNA Metabolism in Antigen-Driven B Cells2011
- Author(s)
  Sakaguchi N
- Journal Title
  
  Scandinavian Journal of Immunology
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021036
[Journal Article] A novel serum carbohydrate marker on mucin 5AC : values for diagnostic and prognostic indicators for cholangiocarcinoma2011
- Author(s)
  Silsirivanit A, et al
- Journal Title
  
  Cancer
  
  Volume: 117 Issue: 15 Pages: 3393-3403
- DOI
  10.1002/cncr.25912
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021036, KAKENHI-PROJECT-23390122
[Journal Article] Germinal center-associated nuclear protein, a human homologue of SAC3, is necessary for centromere cohesion and sister-chromatid exchange during mitosis.2010
- Author(s)
  Nobukazu Okamoto, Kazuhiko Kuwahara, Kazutaka Ohta, Masahiro Kitabatake, Hideya Igarashi, Katsumasa Takagi, Hiroshi Mizuta, Eisaku Kondo, Nobuo Sakaguchi
- Journal Title
  
  Genes to Cells 15
  
  Pages: 471-483
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013069
[Journal Article] GANP-mediated recruitment of activation-induced cytidine deaminase to cell nuclei and to immunoglobulin Variable region DNA.2010
- Author(s)
  Kazuhiko Maeda, Shailendra Kumar Singh, Kazufumi Eda, Masahiro Kitabatake, Phuong Pham, Myron F. Goodman, Nobuo Sakaguchi(Corresponding author)
- Journal Title
  
  J. Biol. Chem. (on line)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013069
[Journal Article] Decreased expression of germinal center-associated nuclear protein is involved in chromosomal instability in malignant gliomas.2009
- Author(s)
  Kazutaka Ohta, Kazuhiko Kuwahara, Zhenhuan Zhang, Keishi Makino, Yoshihiro Komohara, Hideo Nakamura, Jun-Ichi Kuratsu, Nobuo Sakaguchi
- Journal Title
  
  Cancer Sci. 100
  
  Pages: 2069-2076
- NAID
  10027196786
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013069
[Journal Article] GANP suppresses the arginine methyltransferase PRMT5 regulating IL-4-mediated STAT6-signaling to IgE production in B cells.2009
- Author(s)
  Hideya Igarashi, Kazuhiko Kuwahara, Mikoto Yoshida, Yan Xing, Kazuhiko Maeda, Kouji Nakajima, Nobuo Sakaguchi
- Journal Title
  
  Mol. Immunol. 46
  
  Pages: 1031-1041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013069
[Journal Article] Cholangiocarcinomas associated with long-term inflammation express the activation-induced cytidine deaminase and germinal center-associated nuclear protein involved in immunoglobulin V-region diversification2009
- Author(s)
  Waraporn Chan-On, Kazuhiko Kuwahara, Naoya Kobayashi, Kazutaka Ohta, Tatsuya Shimasaki, Banchob Sripa, Chanvit Leelayuwat, Nobuo Sakaguchi
- Journal Title
  
  Int. J. Oncol. 35,2
  
  Pages: 287-295
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013069
[Journal Article] Generation of high affinity monoclonal antibodies for the prevention of HIV infection.2009
- Author(s)
  Sakaguchi N
- Journal Title
  
  Recent Patent of DNA Gene Sequence 3
  
  Pages: 88-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013069
[Journal Article] Germinal center B-cell associated DNA hypomethylation at transcriptional regions of the AID gene.2008
- Author(s)
  Satoru Fujimura, Takeshi Matsui, Kazuhiko Kuwahara, Kazuhiko Maeda, Nobuo Sakaguchi
- Journal Title
  
  Mol. Immunol. 45
  
  Pages: 1712-1719
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013069
[Journal Article] GANP suppresses DNA recombination, measured by direct-repeat b-galactosidase gene construct, but does not suppress the type of recombination applying to immunoclpbulin genes in mammalian cells.2007
- Author(s)
  Mikoto Yoshida, Kazuhiko Kuwahara, Tatsuya Shimasaki, Naomi Nakagata, Masao Matsuoka, Nobuo Sakaguchi
- Journal Title
  
  Genes Cells 12
  
  Pages: 1205-1213
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013069
[Journal Article] Increased expression of germinal center-associated nuclear protein (GANP) is associated with malignant transformation of melanocytes.2006
- Author(s)
  Toshiro Kageshita, Kazuhiko Kuwahara, Masahiro Oka, Donglai Ma, Tomomich Ono, Nobuo Sakaguchi
- Journal Title
  
  J. Dermatol. Sci 42
  
  Pages: 55-63
- NAID
  10020550048
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013069
[Journal Article] Increased expression of GANP RNA-primase is associated with lymphomagenesis.2005
- Author(s)
  Satoru Fujimura, Yan Xing, Motohiro Takeya, Yasuyuki Yamashita, Koichi Ohshima, Kazuhiko Kuwahara, Nobuo Sakaguchi
- Journal Title
  
  Cancer Res. 65
  
  Pages: 5925-5934
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013069
[Journal Article] Protein phosphatase subunit G5PR is needed for inhibition of BCR-induced apoptosis.2005
- Author(s)
  Yan Xing, Hideya Igarashi, Xiaodang, Wang, Nobuo Sakaguchi
- Journal Title
  
  J. Exp. Med. 202
  
  Pages: 707-719
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013069
[Journal Article] The heterodimer of alpha4 and PP2Ac is associated with S6 kinasel in B cells.2005
- Author(s)
  Takeshi Yamashita, Seiji Inui, Kazuhiko Maeda, Ding R.Hua, Katsumasa Takagi, Nobuo Sakaguchi.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 330
  
  Pages: 439-445
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15023248
[Journal Article] Cutting Edge: Double-stranded DNA breaks in the immunoglobulin V-region gene were detected at lower frequency in affinity-maturation impeded GANP-/- mice. (査読有り) J. Immunol.2005
- Author(s)
  Yousuke Kawatani, Hideya Igarashi, Takeshi Matsui, Kazuhiko Kuwahara, Satoru Fujimura, Nobukazu Okamoto, Katsumasa Takagi, Nobuo Sakaguchi
- Journal Title
  
  J. Immunol. 175
  
  Pages: 5615-5618
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013069
[Journal Article] Early Lymphoid Progenitors in Mouse and Man are Highly Sensitive to Glucocorticoids.2005
- Author(s)
  Hideya Igarashi, Kay L.Medina, Takafumi Yokota, Isabel D.Rossi, Nobuo Sakaguchi, Philip C.Comp, Paul W.Kincade.
- Journal Title
  
  Int.Immunol. 17
  
  Pages: 501-511
- NAID
  10019359022
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15023248
[Journal Article] Antibody against T Cell-Dependent Antigen in Ganp Gene-Transgenic Mouse2005
- Author(s)
  Nobuo Sakaguchi et al.
- Journal Title
  
  Journal of Immunology 174
  
  Pages: 4485-4494
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15023248
[Journal Article] Generation of High-Affinity Antibody against T Cell-Dependent Antigen in Ganp Gene-Transgenic Mouse.2005
- Author(s)
  Nobuo Sakaguchi, Tetsuya Kimura, Shuzo Matsushita, Satoru Fujimura, Junji Shibata, Masatake Araki, Tamami Sakamoto, Chiemi Minoda, Kazuhiko Kuwahara.
- Journal Title
  
  J.Immunol. 174
  
  Pages: 4485-4494
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15023248
[Journal Article] Generation of high-affinity antibody against T cell-dependent antigen in ganp gene-transgenic mouse.2005
- Author(s)
  Nobuo Sakaguchi, Tetsuya Kimura, Shuzo Matsushita, Satoru Fujimura, Junji Shibata, Masatake Araki, Tamami Sakamoto, Chiemi Minoda, Kazuhiko Kuwahara
- Journal Title
  
  J. Immunol 174
  
  Pages: 4485-4494
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013069
[Journal Article] The Sac3 homologue shd1 is involved in mitotic progression in mammalian cells.2004
- Author(s)
  Sefat-e-Khuda, Mikoto Yoshida, Yan Xing, Tatsuya Shimasaki, Motohiro Takeya, Kazuhiko Kuwahara, Nobuo Sakaguchi.
- Journal Title
  
  J.Biol.Chem. 279
  
  Pages: 46182-46190
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15023248
[Journal Article] Germinal center-associated nuclear protein contributes to affinity maturation of B cell antigen receptor in T cell-dependent responses.2004
- Author(s)
  Kazuhiko Kuwahara, Satoru Fujimura, YoshimasaTakahashi, Maomi Nakagata, Toshitada Takemori, Shinichi Aizawa, Nobuo Sakaguchi.
- Journal Title
  
  Proc.Natl.Acad.Sci.U.S.A. 101
  
  Pages: 1010-1015
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15023248
[Journal Article] Increased expression of GANP RNA-primase is associated with Lymphomagenesis.
- Author(s)
  Satoru Fujimura, Yan Xing, Motohiro Takeya, Yasuyuki Yamashita, Koichi Ohshima, Kazuhiko Kuwahara, Nobuo Sakaguchi
- Journal Title
  
  Cancer Research (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15023248
[Journal Article] IL-6 blocks a discrete early step in lymphopoiesis.
- Author(s)
  Kazuhiko Maeda, Yoshihiro Baba, Yoshinori Nagai, Kozo Miyazaki, Alexander Malykhin, Koji Nakamura, Paul W Kincade, Nobuo Sakaguchi, K M Coggeshall.
- Journal Title
  
  Blood (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15023248
[Patent] 胆管がん特異的糖鎖エピトープを認識するモノクローナル抗体2009
- Inventor(s)
  阪口薫雄、桑原一彦、荒木令江、坂本珠美
- Industrial Property Rights Holder
  財)くまもとテクノ産業財団
- Industrial Property Number
  2009-025607
- Filing Date
  2009-02-02
- Data Source
  KAKENHI-PROJECT-17013069
[Patent] GANPによる癌抑制遺伝子の活性化方法2006
- Inventor(s)
  阪口薫雄
- Industrial Property Rights Holder
  国立大学法人熊本大学
- Industrial Property Number
  2006-189043
- Filing Date
  2006-07-10
- Data Source
  KAKENHI-PROJECT-17013069
[Patent] GANP DNA(マウス)2006
- Inventor(s)
  阪口薫雄
- Industrial Property Rights Holder
  財団法人くまもとテクノ産業財団
- Filing Date
  2006-11-21
- Data Source
  KAKENHI-PROJECT-17013069
[Patent] 抗GANP抗体(マウス)2005
- Inventor(s)
  阪口薫雄
- Industrial Property Rights Holder
  財団法人くまもとテクノ産業財団
- Filing Date
  2005-09-13
- Data Source
  KAKENHI-PROJECT-17013069
[Presentation] 新しい虚血性心疾患診断バイオマーカーの開発と意義。2015
- Author(s)
  頼仲方一, 頼仲玉珍,光山勝慶，張　田力、阪口薫雄、北本康則.
- Organizer
  第66回日本薬理学会西南部会
- Place of Presentation
  福岡大学薬学部
- Year and Date
  2015-11-16
- Data Source
  KAKENHI-PROJECT-25460337
[Presentation] HIV-1 virus causes disassembly of TREX-2 component GANP from nuclear pores to be taken with integrase in the virus entry process.2014
- Author(s)
  Maeda K, Almofty SA, Shimoda M, Singh SK, Eid MMA, Sakaguchi N.
- Organizer
  The 10th China-Japan Joint Laboratory Workshop Pathogenesis, Gene Regulation and Signal Transduction
- Place of Presentation
  Chinese Academy of Sciences, Beijing, China
- Year and Date
  2014-11-15
- Data Source
  KAKENHI-PROJECT-13F03407
[Presentation] GANP interacts with APOBEC3G and facilitates its encapsidation into the virions to reduce HIV-1 infectivity2014
- Author(s)
  Maeda K, Almofty SA, Singh SK, Eid MMA, Shimoda M, Ikeda T, Koito A, Pham P, Goodman MF, Sakaguchi N.
- Organizer
  Asian-African Research Forum on Emerging and Reemerging Infections 2014
- Place of Presentation
  仙台国際センター(宮城)
- Year and Date
  2014-01-20
- Data Source
  KAKENHI-PROJECT-24659224
[Presentation] GANP plays a regulatory role in the choice of DNA repair pathway by dissociating DNA-PKcs in AID-induced immunoglobulin V-region diversification2014
- Author(s)
  Sakaguchi, N., Eid, M. M. A., Singh, S. K., Almofty, S. A., Shimoda, M, Maeda, K.
- Organizer
  Keystone Symposia Conference Biology of B Cell Responses
- Place of Presentation
  Keystone, Colorado, USA
- Data Source
  KAKENHI-PROJECT-24659224
[Presentation] GANP plays a regulatory role in the choice of DNA repair pathway by dissociating DNA-PKcs in AID-induced immunoglobulin V-region diversification2014
- Author(s)
  Sakaguchi N, Eid MMA, Singh SK, Almofty SA, Shimoda M, Maeda K
- Organizer
  Keystone Symposia Conference Biology of B Cell Responses
- Place of Presentation
  Keystone Conference Center (コロラド, アメリカ)
- Year and Date
  2014-02-13
- Data Source
  KAKENHI-PROJECT-23390122
[Presentation] A host factor GANP involve in anti-HIV-1 infectivity response by facilitating the encapsidation of APOBEC3G into virion core2014
- Author(s)
  Almofty, S. A. Maeda, K. Shimoda, M. Singh, S. K. Eid, M. M. A. Sakaguchi, N.
- Organizer
  International Workshop on Biomedical Engineering at Osaka Institute of Technology
- Place of Presentation
  Omiya Campus of Osaka Institute of Technology, Osaka
- Year and Date
  2014-11-16
- Data Source
  KAKENHI-PROJECT-13F03407
[Presentation] GANP plays a regulatory role in the choice of DNA repair pathway by dissociating DNA-PKcs in AID-induced immunoglobulin V-region diversification2014
- Author(s)
  Sakaguchi, N., Eid, M. M. A., Singh, S. K., Almofty, S. A., Shimoda, M, Maeda, K.
- Organizer
  Keystone Symposia Conference Biology of B Cell Responses
- Place of Presentation
  Keystone, Colorado, USA
- Data Source
  KAKENHI-PROJECT-23390122
[Presentation] MAPキナーゼTNNI3Kの機能解析と心臓突然死を抑制するため新薬の開発。2014
- Author(s)
  頼仲方一、頼仲玉珍、張田力、阪口薫雄、光山勝慶、北本康則
- Organizer
  第87回日本薬理学会
- Place of Presentation
  仙台、仙台国際センター
- Data Source
  KAKENHI-PROJECT-25460337
[Presentation] HIV感染経路における宿主因子GANPの役割2013
- Author(s)
  前田和彦、サーラアルモフティ、シェイレンドラシン、モハメドエイド、下田真唯子、川畑輝弥、阪口薫雄
- Organizer
  第27回日本エイズ学会学術集会・総会
- Place of Presentation
  市民会館崇城大学ホール(熊本市民会館)、熊本市国際交流会館(熊本)
- Year and Date
  2013-11-21
- Data Source
  KAKENHI-PROJECT-24659224
[Presentation] Functional analysis of Tnni3k gene and its significance for suppressing cardiac sudden death.2013
- Author(s)
  ZF Lai (H.Yorinaka), Y-Z Chen, T-L Zhang, N Sakaguchi, S Kim-Mitsuyama
- Organizer
  The American Heart Association’s Scientific Sessions 2013
- Place of Presentation
  Convention Center, Dallas, CA
- Data Source
  KAKENHI-PROJECT-25460337
[Presentation] Mammalian Leng8 carrying a Sac3/GANP homologous region unregulated in germinal center B cells is involved in regulation of BCR-mediated proliferation2013
- Author(s)
  Kuwahara, K., Kitabatake, M., Kitamura, D., Sakaguchi, N.
- Organizer
  The 42th Annual Meeting of the Japanese Society for Immunology
- Place of Presentation
  Makuhari Messe
- Data Source
  KAKENHI-PROJECT-24659224
[Presentation] Role of mammalian TREX-2 component GANP in HIV-1 infection2013
- Author(s)
  Maeda, K., Almofty, S. A., Shimoda, M., Singh, S. K., Eid, M. M. A., Kawabata, T., Ikeda, T., Shida, H., Koito, A., Sakaguchi, N.
- Organizer
  The 14th Kumamoto AIDS Seminar GCOE Joint International Symposium
- Place of Presentation
  Kumamoto Castle Hotel, Aso Resort Grandvrio Hotel
- Data Source
  KAKENHI-PROJECT-24659224
[Presentation] Role of mammalian TREX-2 component GANP in HIV-1 infection2013
- Author(s)
  Maeda, K., Almofty, S. A., Shimoda, M., Singh, S. K., Eid, M. M. A., Kawabata, T., Ikeda, T., Shida, H., Koito, A., Sakaguchi, N.
- Organizer
  The 14th Kumamoto AIDS Seminar GCOE Joint International Symposium
- Place of Presentation
  Kumamoto Castle Hotel, Aso Resort Grandvrio Hotel
- Data Source
  KAKENHI-PROJECT-23390122
[Presentation] HIV感染経路における宿主因子GANPの役割2013
- Author(s)
  前田和彦, アルモフティ・サーラアミーン, シン・シャイレンドラクマール, エイド・モハメドアバス, 下田真唯子, 川畑輝弥, 阪口薫雄
- Organizer
  第27回日本エイズ学会学術集会
- Place of Presentation
  市民会館崇城大学ホール(熊本市民会館)、熊本市国際交流会館民会館崇城大学ホール(熊本市民会館)、熊本市国際交流会館
- Data Source
  KAKENHI-PROJECT-24659224
[Presentation] 新しい虚血性心疾患診断バイオマーカーの開発と意義。2013
- Author(s)
  頼仲方一、頼仲玉珍、光山勝慶、張田力、阪口薫雄, 北本康則
- Organizer
  第66回日本薬理学会西南部会
- Place of Presentation
  福岡大学薬学部17号館、福岡
- Data Source
  KAKENHI-PROJECT-25460337
[Presentation] HIV感染経路における宿主因子GANPの役割2013
- Author(s)
  前田和彦, アルモフティ・サーラアミーン, シン・シャイレンドラクマール, エイド・モハメドアバス, 下田真唯子, 川畑輝弥, 阪口薫雄
- Organizer
  第27回日本エイズ学会学術集会
- Place of Presentation
  市民会館崇城大学ホール(熊本市民会館)、熊本市国際交流会館
- Data Source
  KAKENHI-PROJECT-23390122
[Presentation] GANP regulates transcription and nucleosome occupancy at the immunoglobulin variable region for AID-accession2013
- Author(s)
  Maeda K, Singh SK, Eid MMA, Almofty SA, Shimoda M, Kawabata T, Sakaguchi N.
- Organizer
  The 42th Annual Meeting of the Japanese Society for Immunology
- Place of Presentation
  千葉幕張メッセ
- Data Source
  KAKENHI-PROJECT-13F03407
[Presentation] GANP regulates transcription and nucleosome occupancy at the immunoglobulin variable region for AID-accession2013
- Author(s)
  Maeda K, Singh SK, Eid MMA, Almofty SA, Sakaguchi N.
- Organizer
  The 9th China-Japan Joint Laboratory Workshop : Pathogenesis, Gene Regulation and Signal Transduction
- Place of Presentation
  Chinese Academy of Sciences (北京、中国)
- Year and Date
  2013-11-01
- Data Source
  KAKENHI-PROJECT-24659224
[Presentation] GANP regulates transcription and nucleosome occupancy at the immunoglobulin variable region for AID-accession2013
- Author(s)
  Maeda, K., Singh, S. K., Eid, M. M. A., Almofty, S. A., Shimoda, M., Kawabata, T., Sakaguchi, N.
- Organizer
  The 42th Annual Meeting of the Japanese Society for Immunology
- Place of Presentation
  千葉幕張メッセ
- Data Source
  KAKENHI-PROJECT-23390122
[Presentation] Role of mammalian TREX-2 component in HIV-1 mRNA export2013
- Author(s)
  Almofty SA, Maeda K, Singh SK, Eid MMA, Shimoda M, Kawabata T, Sakaguchi N.
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ(千葉)
- Year and Date
  2013-12-12
- Data Source
  KAKENHI-PROJECT-24659224
[Presentation] 乳癌発症における TREX2 複合体の役割2013
- Author(s)
  桑原一彦、岩瀬弘敬、阪口薫雄
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24659224
[Presentation] Protein phosphatase subunit G5PR regulates the plasma blast differentiation and autoantibody production of peritoneal B-1a cells2013
- Author(s)
  Kitabatake, M., Zhang, T. L., Kuwahara K., Sakaguchi, N.
- Organizer
  The 42th Annual Meeting of the Japanese Society for Immunology
- Place of Presentation
  千葉幕張メッセ
- Data Source
  KAKENHI-PROJECT-23390122
[Presentation] GANP regulates transcription and nucleosome occupancy at the immunoglobulin variable region for AID-accession2013
- Author(s)
  Maeda K, Singh SK, Eid MMA, Almofty SA, Shimoda M, Kawabata T, Sakaguchi N
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ(千葉)
- Year and Date
  2013-12-13
- Data Source
  KAKENHI-PROJECT-23390122
[Presentation] Protein phosphatase subunit G5PR regulates the plasma blast differentiation and autoantibody production of peritoneal B-1a cells2013
- Author(s)
  Kitabatake, M., Zhang, T. L., Kuwahara K., Sakaguchi, N.
- Organizer
  The 42th Annual Meeting of the Japanese Society for Immunology
- Place of Presentation
  Makuhari Messe
- Data Source
  KAKENHI-PROJECT-24659224
[Presentation] 乳癌発症におけるmRNA核外輸送複合体分子GANP異常の関与2013
- Author(s)
  桑原一彦、阪口薫雄
- Organizer
  第17回日本がん分子標的治療学会学術集会
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-23390122
[Presentation] Role of mammalian TREX-2 component in HIV-1 mRNA export2013
- Author(s)
  Almofty, S. A., Maeda, K., Singh, S. K., Eid, M. M. A., Shimoda, M., Kawabata, T., Sakaguchi, N.
- Organizer
  The 42th Annual Meeting of the Japanese Society for Immunology
- Place of Presentation
  Makuhari Messe
- Data Source
  KAKENHI-PROJECT-24659224
[Presentation] B cell-associated regulation of DNA repair pathway through interaction with DNA-PKcs in IgV-region diversification2013
- Author(s)
  Eid MMA, Maeda K, Almofty SA, Singh SK, Shimoda M, Sakaguchi N
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ(千葉)
- Year and Date
  2013-12-13
- Data Source
  KAKENHI-PROJECT-23390122
[Presentation] Role of mammalian TREX-2 component in HIV-1 mRNA export2013
- Author(s)
  Almofty SA, Maeda K, Singh SK, Eid MMA, Shimoda M, Kawabata T, Sakaguchi N.
- Organizer
  The 42th Annual Meeting of the Japanese Society for Immunology
- Place of Presentation
  千葉幕張メッセ
- Data Source
  KAKENHI-PROJECT-13F03407
[Presentation] B cell-associated regulation of DNA repair pathway through interaction with DNA-PKcs in IgV-region diversification2013
- Author(s)
  Eid, M. M. A., Maeda, K., Almofty, S. A., Singh, S. K., Shimoda, M., Sakaguchi, N.
- Organizer
  The 42th Annual Meeting of the Japanese Society for Immunology
- Place of Presentation
  千葉幕張メッセ
- Data Source
  KAKENHI-PROJECT-23390122
[Presentation] GANP regulates transcription and nucleosome occupancy at the immunoglobulin variable region for AID-accession2013
- Author(s)
  Maeda, K., Singh, S. K., Eid, M. M. A., Almofty, S. A., Shimoda, M., Kawabata, T., Sakaguchi, N.
- Organizer
  The 42th Annual Meeting of the Japanese Society for Immunology
- Place of Presentation
  Makuhari Messe
- Data Source
  KAKENHI-PROJECT-24659224
[Presentation] B cell-associated regulation of DNA repair pathway through interaction with DNA-PKcs in IgV-region diversification2013
- Author(s)
  Eid, M. M. A., Maeda, K., Almofty, S. A., Singh, S. K., Shimoda, M., Sakaguchi, N.
- Organizer
  The 42th Annual Meeting of the Japanese Society for Immunology
- Place of Presentation
  Makuhari Messe
- Data Source
  KAKENHI-PROJECT-24659224
[Presentation] Role of mammalian TREX-2 component in HIV-1 mRNA export2013
- Author(s)
  Almofty, S. A., Maeda, K., Singh, S. K., Eid, M. M. A., Shimoda, M., Kawabata, T., Sakaguchi, N.
- Organizer
  The 42th Annual Meeting of the Japanese Society for Immunology
- Place of Presentation
  千葉幕張メッセ
- Data Source
  KAKENHI-PROJECT-23390122
[Presentation] Role of mammalian TREX-2 component GANP in HIV-1 infection2013
- Author(s)
  Maeda K, Almofty SA, Shimoda M, Singh SK, Eid MMA, Kawabata T, Ikeda T, Shida H, Koito A, Sakaguchi N.
- Organizer
  第14回熊本エイズセミナーGCOEジョイント国際シンポジウム
- Place of Presentation
  熊本キャッスルホテル、阿蘇リゾートグランヴィリオホテル(熊本)
- Year and Date
  2013-10-30
- Data Source
  KAKENHI-PROJECT-24659224
[Presentation] 乳癌発症における TREX2 複合体の役割2013
- Author(s)
  桑原一彦、岩瀬弘敬、阪口薫雄
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23390122
[Presentation] MAPキナーゼTNNI3Kを用いた新しい心疾患診断薬の開発と意義。2013
- Author(s)
  頼仲方一、頼仲玉珍、張田力、阪口薫雄
- Organizer
  第15回応用薬理シンポジウム
- Place of Presentation
  東京コクヨホール（品川）
- Data Source
  KAKENHI-PROJECT-25460337
[Presentation] Mammalian Leng8 carrying a Sac3/GANP homologous region unregulated in germinal center B cells is involved in regulation of BCR-mediated proliferation2013
- Author(s)
  Kuwahara, K., Kitabatake, M., Kitamura, D., Sakaguchi, N.
- Organizer
  The 42th Annual Meeting of the Japanese Society for Immunology
- Place of Presentation
  千葉幕張メッセ
- Data Source
  KAKENHI-PROJECT-23390122
[Presentation] 乳癌発症におけるmRNA核外輸送複合体分子GANP異常の関与2013
- Author(s)
  桑原一彦、阪口薫雄
- Organizer
  第17回日本がん分子標的治療学会学術集会
- Place of Presentation
  国立京都国際会館立京都国際会館
- Data Source
  KAKENHI-PROJECT-24659224
[Presentation] B cell-associated regulation of DNA repair pathway through interaction with DNA-PKcs in IgV-region diversification2013
- Author(s)
  Eid MMA, Maeda K, Almofty SA, Singh SK, Shimoda M, Sakaguchi N.
- Organizer
  The 42th Annual Meeting of the Japanese Society for Immunology
- Place of Presentation
  千葉幕張メッセ
- Data Source
  KAKENHI-PROJECT-13F03407
[Presentation] Role of GANP in transcriptional regulation of immunoglobulin gene locus2012
- Author(s)
  Sakaguchi N, Singh SK, Almofty SA, Eid MMA, Ono M, Maeda K
- Organizer
  Keystone Symposia Mutations, Malignancy and Memory-Antibodies and Immunity
- Place of Presentation
  Boston, Boston Park Plaza & Towers (ボストン, アメリカ)
- Year and Date
  2012-03-21
- Data Source
  KAKENHI-PROJECT-23390122
[Presentation] 高親和性B細胞制御と抗癌単クローン抗体2012
- Author(s)
  阪口薫雄
- Organizer
  第16回日本がん免疫学会総会
- Place of Presentation
  北海道大学　学術交流会館
- Data Source
  KAKENHI-PROJECT-23390122
[Presentation] Role of GANP in transcriptional regulation of immunoglobulin gene locus2012
- Author(s)
  Sakaguchi N
- Organizer
  Keystone Symposia Mutations, Malignancy and Memory-Antibodies and Immunity
- Place of Presentation
  Boston Park Plaza & Towers
- Year and Date
  2012-03-20
- Data Source
  KAKENHI-PUBLICLY-22021036
[Presentation] Targeting the rearranged immunoglobulin V-region locus in B-cells by the histone acetyl transcriptase activity of GANP2012
- Author(s)
  Maeda K, Singh SK, Almofty SA, Eid MMA, Ono M, Sakaguchi N
- Organizer
  第6回日本エピジェネティクス研究会年会
- Place of Presentation
  学術総合センター(東京)
- Year and Date
  2012-05-14
- Data Source
  KAKENHI-PROJECT-23390122
[Presentation] Mammalian TREX-2 component GANP is involved in HIV-1 mRNA export2012
- Author(s)
  Maeda K, Almofty SA, Singh SK, Eid MMA, Shimoda M, Ikeda T, Shida H, Koito A, Pham P, Goodman MF, Sakaguchi N.
- Organizer
  第13回熊本エイズセミナーGCOEジョイント国際シンポジウム
- Place of Presentation
  ホテル日航熊本、阿蘇リゾートグランヴィリオホテル(熊本)
- Year and Date
  2012-10-26
- Data Source
  KAKENHI-PROJECT-24659224
[Presentation] Regulation of immunoglobulin variable region diversification through GANP-mediated regulation of DNA double-strand break repair machinery2012
- Author(s)
  Eid MMA, Maeda K, Singh SK, Almofty SA, Shimoda M, Sakaguchi N
- Organizer
  第41回日本免疫学会学術集会
- Place of Presentation
  神戸国際会議場, 神戸国際展示場, 神戸ポートピアホテル(兵庫)
- Year and Date
  2012-12-05
- Data Source
  KAKENHI-PROJECT-23390122
[Presentation] GANP regulates APOBEC3G targeting for reduction of HIV-1 infectivity2012
- Author(s)
  Singh SK, Maeda K, Eid MMA, Almofty SA, Shimoda M, Sakaguchi N.
- Organizer
  第41回日本免疫学会学術集会
- Place of Presentation
  神戸国際会議場、神戸国際展示場、神戸ポートピアホテル(兵庫)
- Year and Date
  2012-12-05
- Data Source
  KAKENHI-PROJECT-24659224
[Presentation] Escorting APOBEC3G toward the full length HIV-1 mRNA at the cytoplasmic P bodies2012
- Author(s)
  Almofty SA, Maeda K, Singh SK, Eid MMA, Shimoda M, Sakaguchi N.
- Organizer
  第41回日本免疫学会学術集会
- Place of Presentation
  神戸国際会議場、神戸国際展示場、神戸ポートピアホテル(兵庫)
- Year and Date
  2012-12-05
- Data Source
  KAKENHI-PROJECT-24659224
[Presentation] GANP regulates transcription and nucleosome occupancy at the immunoglobulin variable region for AID-accession2012
- Author(s)
  Maeda K, Singh SK, Almofty SA, Eid MMA, Shimoda M, Sakaguchi N
- Organizer
  第41回日本免疫学会学術集会
- Place of Presentation
  神戸国際会議場, 神戸国際展示場, 神戸ポートピアホテル(兵庫)
- Year and Date
  2012-12-05
- Data Source
  KAKENHI-PROJECT-23390122
[Presentation] GANPを介したAPOBEC3Gの抗HIV感染阻止機構の解析2012
- Author(s)
  前田和彦、サーラアルモフティ、シェイレンドラシン、モハメドエイド、下田真唯子、池田輝政、小糸厚、阪口薫雄
- Organizer
  第26回日本エイズ学会学術集会・総会
- Place of Presentation
  慶応義塾大学、日吉キャンパス(神奈川)
- Year and Date
  2012-11-25
- Data Source
  KAKENHI-PROJECT-24659224
[Presentation] Role of GANP in transcriptional regulation of immunoglobulin gene locus2012
- Author(s)
  Sakaguchi N
- Organizer
  Keystone Symposia Mutations, Malignancy and Memory-Antibodies and Immunity
- Place of Presentation
  Boston Park Plaza & Towers・アメリカ
- Year and Date
  2012-03-20
- Data Source
  KAKENHI-PROJECT-23390122
[Presentation] 乳腺上皮細胞におけるエストロゲンが誘導するDNA損傷においてGANPは重要な役割を果たす2012
- Author(s)
  阪口薫雄
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ホテルロイトン札幌
- Data Source
  KAKENHI-PROJECT-23390122
[Presentation] Analysis of GANP-associated complex in B-cell nuclei2011
- Author(s)
  Maeda K, Singh SK, Almofty SA, Eid MMA, Sakaguchi N
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ(千葉)
- Year and Date
  2011-11-28
- Data Source
  KAKENHI-PROJECT-23390122
[Presentation] GANP augments the immunoglobulin V region gene conversion via Ku70 dependent mechanism2011
- Author(s)
  Eid MMA, Maeda K, Singh SK, Almofty SA, Sakaguchi N
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ(千葉)
- Year and Date
  2011-11-28
- Data Source
  KAKENHI-PROJECT-23390122
[Presentation] 高親和性単クローン抗体による胆管癌特異的糖鎖エピトープの同定2011
- Author(s)
  阪口薫雄
- Organizer
  日本がん免疫学会
- Place of Presentation
  千里ライフサイエンスセンター大阪
- Year and Date
  2011-07-01
- Data Source
  KAKENHI-PUBLICLY-22021036
[Presentation] Transcriptional targeting at immunoglobulin V-region locus by an RNA-export molecule GANP2011
- Author(s)
  Maeda K, Singh SK, Almofty SA, Eid MAA, Sakaguchi N
- Organizer
  第5回日本エピジェネティクス研究会年会
- Place of Presentation
  KKRホテル熊本(熊本)
- Year and Date
  2011-05-20
- Data Source
  KAKENHI-PROJECT-23390122
[Presentation] Involvement of GANP in transcriptional regulation of immunoglobulin gene locus2011
- Author(s)
  Singh SK, Maeda K, Almofty SA, Eid MMA, Sakaguchi N
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ(千葉)
- Year and Date
  2011-11-28
- Data Source
  KAKENHI-PROJECT-23390122
[Presentation] RNA metabolism and antibody affinity maturation2011
- Author(s)
  Sakaguchi N
- Organizer
  Immunology Symposium Basel (ISB) 2011 on "Immune Responses and Autoimmunity"
- Place of Presentation
  University of Basel、スイフ
- Year and Date
  2011-06-10
- Data Source
  KAKENHI-PROJECT-23390122
[Presentation] RNA metabolism and antibody affinity maturation2011
- Author(s)
  Sakaguchi N
- Organizer
  Immunology Symposium Basel (ISB) 2011 on "Immune Responses and Autoimmunity"
- Place of Presentation
  University of Basel
- Year and Date
  2011-06-10
- Data Source
  KAKENHI-PUBLICLY-22021036
[Presentation] 高親和性単クローン抗体による胆管癌特異的糖鎖エピトープの同定2011
- Author(s)
  阪口薫雄
- Organizer
  日本がん免疫学会
- Place of Presentation
  千里ライフサイエンスセンター大阪
- Year and Date
  2011-07-01
- Data Source
  KAKENHI-PROJECT-23390122
[Presentation] GANP is a host factor that regulates Apobec3G encapsidation to HIV-1 viruses2010
- Author(s)
  Sakaguchi N
- Organizer
  Asian-African Research Forum 2010
- Place of Presentation
  Hanoi ベトナムホテルメリアハノイ
- Year and Date
  2010-11-01
- Data Source
  KAKENHI-PUBLICLY-22021036
[Presentation] Apobec3GのHIV-1粒子内への取り込みを制御する宿主因子の同定2010
- Author(s)
  阪口薫雄
- Organizer
  第24回日本エイズ学会学術集会
- Place of Presentation
  グランドプリンスホテル高輪/ザ・プリンスさくらタワー東京
- Year and Date
  2010-11-24
- Data Source
  KAKENHI-PUBLICLY-22021036
[Presentation] Molecular mechanism of immunoglobulin V-region diversification and its application in medical sciences2010
- Author(s)
  阪口薫雄
- Organizer
  日本ヒトプロテオーム機構第8回大会(日本プロテオーム学会2010年会)・第6回日本臨床プロテオーム研究会・連合大会
- Place of Presentation
  東京ベイホテル東急
- Year and Date
  2010-07-26
- Data Source
  KAKENHI-PUBLICLY-22021036
[Presentation] Regulation of immune function by controlling RNA metabolism. The 2nd Workshop of Synthetic Immunology2010
- Author(s)
  Sakaguchi N
- Organizer
  The 2nd Workshop of Synthetic Immunology
- Place of Presentation
  Kyoto University Shiran Kaikan, Inamori Hall
- Year and Date
  2010-12-17
- Data Source
  KAKENHI-PUBLICLY-22021036
[Presentation] mRNA核外輸送分子GANP異常による乳癌発症2009
- Author(s)
  阪口薫雄
- Organizer
  第13回日本がん分子標的治療学会
- Place of Presentation
  ホテルクレメント徳島
- Data Source
  KAKENHI-PROJECT-17013069
[Presentation] Molecular Mechanism of Immunoglobulin V-region Diversification and its Application in Medical Sciences.2009
- Author(s)
  阪口薫雄
- Organizer
  The 2009 FallConference of The Korean Association of Immunologists.
- Place of Presentation
  Charoen Thani Princess Hotel korea
- Year and Date
  2009-11-10
- Data Source
  KAKENHI-PROJECT-17013069
[Presentation] Critical role of GANP in nuclear export of mRNA involved in mammalian cell division2009
- Author(s)
  阪口薫雄
- Organizer
  第68回日本癌学会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-17013069
[Presentation] GANP plays a critical role in the final stage of immunoglobulin V-region somatic hypermutation for generation of high-affinity antigen-specific antibody
- Author(s)
  Eid, M. M. A. Maeda, K. Singh, S. K. Almofty, S. A. Shimoda, M. Sakaguchi, N.
- Organizer
  The 43th Annual Meeting of the Japanese Society for Immunology
- Place of Presentation
  Kyoto International Conference Center, Kyoto
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-13F03407
[Presentation] Role of GANP in the DNA repair for AID-induced somatic hypermutation generating high affinity antibodies
- Author(s)
  Sakaguchi, N. Eid, M. M. A. Singh, S. K. Almofty, S. A. Shimoda, M Maeda, K.
- Organizer
  The 2nd Symposium of International Immunological Memory and Vaccine Forum
- Place of Presentation
  La Jolla Institute for Allergy & Immunology, San Diego, CA, USA
- Year and Date
  2014-08-25 – 2014-08-26
- Data Source
  KAKENHI-PROJECT-13F03407
[Presentation] Molecular mechanism of transcription and epigenetic alteration at immunoglobulin variable gene heavy chain locus induced by GANP
- Author(s)
  Singh, S. K. Maeda, K. Eid, M. M. A. Almofty, S. A. Shimoda, M Kawabata, T Sakaguchi, N.
- Organizer
  Immunology 2014 The American Association of Immunologists Annual Meeting
- Place of Presentation
  David L. Lawrence Convention Center, Pittsburgh, Pennsylvania, USA
- Year and Date
  2014-05-02 – 2014-05-06
- Data Source
  KAKENHI-PROJECT-13F03407
[Presentation] ヒトRNA輸送TREX-2因子GANPのHIV-1抵抗性の分子機序
- Author(s)
  前田和彦アルモフティ・サーラアミーン下田真唯子シン・シャイレンドラクマールエイド・モハメドアバス川畑輝弥池田輝政小糸厚阪口薫雄
- Organizer
  第28回日本エイズ学会学術集会
- Place of Presentation
  大阪国際会議場、大阪
- Year and Date
  2014-12-03 – 2014-12-05
- Data Source
  KAKENHI-PROJECT-13F03407
[Presentation] GANP plays a role in the LINE-1 life cycle in somatic cells,
- Author(s)
  Shimoda, M Maeda, K. Almofty, S. A. Singh, S. K. Eid, M. M. A. Sakaguchi, N.
- Organizer
  第8回日本エピジェネティクス研究会年会
- Place of Presentation
  伊藤国際学術研究センター（東京大学構内）、東京
- Year and Date
  2014-05-25 – 2014-05-27
- Data Source
  KAKENHI-PROJECT-13F03407
[Presentation] JNK regulatory molecule G5PR induces peritoneal B1a cells into IgG autoantibody-producing plasmablasts.
- Author(s)
  Kitabatake M, Soma M, Zhang T, and Sakaguchi N.
- Organizer
  第43回日本免疫学会
- Place of Presentation
  京都国際会議場
- Year and Date
  2014-11-10 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-25460337
[Presentation] GANP takes part of the function of TREX-2 complex for exporting non-coding RNAs in B-cells
- Author(s)
  Maeda K, Almofty SA, Singh SK, Shimoda M, Eid MMA, Sakaguchi N.
- Organizer
  The 43th Annual Meeting of the Japanese Society for Immunology
- Place of Presentation
  Kyoto International Conference Center, Kyoto
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-13F03407
[Presentation] GANP that interacts with HIV-1 integrase inherently enhances retrotransposition.
- Author(s)
  Shimoda, M. Maeda, K. Almofty, S. A. Singh, S. K. Eid, M. M. A. Koito, A. Sakaguchi, N.
- Organizer
  15th Kumamoto AIDS Seminar
- Place of Presentation
  Hotel Nikko Kumamoto, Aso Resort Grandvrio Hotel, Kumamoto, Japan
- Year and Date
  2014-10-01 – 2014-10-03
- Data Source
  KAKENHI-PROJECT-13F03407
[Presentation] Regulation of selective non-coding RNA species involved in B-cell maturation by AID-interacting molecule GANP
- Author(s)
  Maeda, K. Shimoda, M Singh, S. K. Almofty, S. A. Eid, M. M. A. Sakaguchi, N.
- Organizer
  Keystone Symposia Conference The Golden Anniversary of B Cell Discovery
- Place of Presentation
  Fairmont Banff Springs, Banff, Alberta, Canada
- Year and Date
  2015-03-22 – 2015-03-27
- Data Source
  KAKENHI-PROJECT-13F03407
[Presentation] A TREX-2 component GANP is dispersed from the nuclear envelope during HIV-1 virus entry and associated with integrase in the host cell nucleus.
- Author(s)
  Almofty, S. A. Maeda, K. Shimoda, M. Singh, S. K. Eid, M. M. A. Koito, A. Sakaguchi, N.
- Organizer
  15th Kumamoto AIDS Seminar
- Place of Presentation
  Hotel Nikko Kumamoto, Aso Resort Grandvrio Hotel, Kumamoto, Japan
- Year and Date
  2014-10-01 – 2014-10-03
- Data Source
  KAKENHI-PROJECT-13F03407
[Presentation] Mechanism of a activation of LINE-1 retrotransposition in somatic cells
- Author(s)
  Shimoda, M. Maeda, K. Almofty, S. A. Singh, S. K. Eid, M. M. A. Sakaguchi, N.
- Organizer
  The 43th Annual Meeting of the Japanese Society for Immunology
- Place of Presentation
  Kyoto International Conference Center, Kyoto
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-13F03407
[Presentation] GANP-mediated APOBEC3G targeting in generation of non-infectious HIV-1viruses
- Author(s)
  Maeda, K. Almofty, S. A. Shimoda, M Singh, S. K. Eid, M. M. A. Sakaguchi, N.
- Organizer
  The 2nd Symposium of International Immunological Memory and Vaccine Forum
- Place of Presentation
  La Jolla Institute for Allergy & Immunology, San Diego, CA, USA
- Year and Date
  2014-08-25 – 2014-08-26
- Data Source
  KAKENHI-PROJECT-13F03407
[Presentation] APOBEC3G-associated GANP in HIV-1 virion initially interacts with the viral integration complex and might regulate viral integration into the host genome
- Author(s)
  Almofty, S. A. Maeda, K. Shimoda, M. Singh, S. K. Eid, M. M. A. Sakaguchi, N.
- Organizer
  The 43th Annual Meeting of the Japanese Society for Immunology
- Place of Presentation
  Kyoto International Conference Center, Kyoto
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-13F03407

1. SAITO Takashi (50205655)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. KATSURA Yoshimoto (90027095)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. TANIGUCHI Masaru (80110310)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. KISHIMOTO Tadamitsu (10093402)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. OKUMURA Ko (50009700)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. SASAZUKI Takehiko (50014121)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 乾誠治 (70243384)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. TAKEMORI Toshitada (60114295)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. TAKATSU Kiyoshi (10107055)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. HIRANO Toshio (40136718)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. SUGAMURA Kazuo (20117360)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. NISHIKAWA Shin-ichi (60127115)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KUZUYAMA Tomohisa (30280952)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. YOKOYAMA Kenji (80242121)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. YASUDA Kunio (30025473)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. KOSEKI Haruhiko (40225446)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. WATANABE Takeshi (40028684)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. Yorinaka (Lai) Hoichi (Zhong-Fang) (90244110)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. YORINAKA Gyokuchin (50418828)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
20. 三宅健介 (60229812)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 湊長博 (40137716)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 高浜洋介 (20183858)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 烏山一 (60195013)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 黒崎知博 (50178125)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 上出利光 (00160185)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 本庶佑 (80090504)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 坂口志文 (30280770)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 菊谷仁 (80161412)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 清野宏 (10271032)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 嶋田一夫 (70196476)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 堀之内末治 (80143410)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 志村令郎 (60025426)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 鎌田博 (00169608)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 山田康之 (50026415)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 軽部征夫 (50089827)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. 別府輝彦 (80011873)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. 荒瀬尚 (10261900)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. 村上正晃 (00250514)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. ZHANG Tianli

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
40. KITAMOTO Yasunori

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
41. WANG Xiaoping

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
42. WANG Boqun

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
43. LIU Xiaozhen

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
44. JIANG Baohong

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
45. MATHIS D.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
46. BENOIST C

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
47. PIATIGORSKY ジェイ

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
48. MARTY J.L.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
49. THOMPSON C.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
50. GOSSLER A

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
51. SINGH Shailendra

# of Collaborated Projects: 1 results

# of Collaborated Products: 19 results
52. SINGH Shailendra Kumar

# of Collaborated Projects: 1 results

# of Collaborated Products: 18 results
53. MAEDA Kazuhiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
54. TSURUI Hiromichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
55. 頼仲方

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results

SAKAGUCHI NOBUO 阪口 薫雄

SAKAGUCHI Nobuo 坂口 薫雄

Research Projects

Research Products

Co-Researchers

Circulating TNNI3K levels are useful diagnosis biomarker for ischemic myocardial diseases

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

リンパ細胞のＲＮＡ輸送からタンパク質翻訳に至る選択的調節機構の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of HIV-1 restriction factor Apobec3G by mRNA export factorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular mechanism of the selective AID targeting at the IgV-regionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Lyn信号伝達における高親和性B細胞選択の分子信号Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role of the RNA-primase GANP in cancer developmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

An experimental mouse model of spontaneous generation of HodgkinDisease by introduction of GANP RNA-primase genePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Acquisition of Signal Information for Immune Surveillance and Determination of Immune Responses

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

S6キナーゼ活性制御分子α4の機能と治療への解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

細胞抗原レセプターシグナル伝達分子α4からのS6キナーゼ活性化誘導の研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

B細胞の抗原認識と活性化制御

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

細胞抗原レセプターシグナル伝達分子α4からのS6キナーゼ活性化誘導の研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

レパートリー形成の分子機構

Principal Investigator

Project Period (FY)

SAKAGUCHI NOBUO 阪口薫雄

SAKAGUCHI Nobuo 坂口薫雄