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HINO OKIO  樋野 興夫

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HINO Okio  樋野 興夫

樋野 興夫  ヒノ オキオ

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Researcher Number 90127910
Other IDs
External Links
Affiliation (Current) 2025: 順天堂大学, 医学部, 客員教授
Affiliation (based on the past Project Information) *help 2019 – 2023: 順天堂大学, 医学部, 客員教授
2003 – 2018: 順天堂大学, 医学部, 教授
2007: 順天堂大学, 医学部・, 教授
2004 – 2005: 順天堂大学, 病理学部, 教授
2001 – 2002: 財団法人癌研究会, 癌研究所・実験病理部, 部長 … More
2000: Cancer Institute, Dept.of Experimental Pathology, Chief, 癌研究所・実験病理部, 部長
1999: 癌研究所, 病理部, 部長
1998 – 1999: Cancer Institute, Dept.of EXperimental Pathology, Chief, 癌研究所・実験病理部, 部長
1998: 癌研究会, 癌研究所 実験病理部, 部長
1998: 癌研究会, 癌研究所・実験病理部, 部長
1997: 財団法人癌研究会, 癌研究所・実験病理部, 部長
1993 – 1997: 財団法人癌研究會, 癌研究所・実験病理部, 部長
1995: 癌研究会研究所, 実験病理部, 部長
1995: Cancer Institute, Department of Experimental Pathology, Chief, 実験病理部, 部長
1994: 財団法人癌研究会研究所, 実験病理部, 部長
1994: 財団法人癌研究會, 実験病理部, 部長
1992 – 1994: (財)癌研究会癌研究所, 実験病理部, 部長
1993: 癌研究会癌研究所, 実験病理部, 部長
1993: 財団法人癌研究曾, 癌研究所実験病理部, 部長
1992 – 1993: 癌研究会癌研究所, 実験病理, 部長
1992: (財)癌研究会, 癌研究所・実験病理部, 部長
1989: 癌研究会癌研究所病理部, 研究員
1988: 癌研究会, 癌研究所, 研究員
1988: 癌研究会, 癌研究所病理部, 研究員
1988: 癌研究会癌研究所, 病理部, 研究員
1987: 癌研究会, 癌研究所・病理部, 研究員
1987: 癌研究所, 研究員
1986: (財)癌研究会癌研究所, 病理部, 研究員
1986: 癌研究会癌研究所, 研究員 Less
Review Section/Research Field
Principal Investigator
Experimental pathology / Biological Sciences / Experimental pathology / Developmental mechanisms and the body works / Laboratory animal science / Cancer epidemiology and prevention
Except Principal Investigator
Hygiene / Laboratory animal science / Tumor diagnostics / Basic Section 09040:Education on school subjects and primary/secondary education-related … More / Lifelong developmental nursing / Gastroenterology / Nerve anatomy/Neuropathology / Religious studies / 小児外科 / Experimental pathology Less
Keywords
Principal Investigator
疾患モデル / TSC2遺伝子 / 癌抑制遺伝子 / 多段階発がん / 遺伝性がん / 遺伝性癌 / Eker rat / Tumor suppressor gene / ヒト結節性硬化症 / Animal model … More / dbpA / Nihon rat / Niban gene / Tsc 2 gene / Tsc 1 gene / TSC1遺伝子 / Tuberous sclerosis / TSC2 gene / Hereditary cancer / 遺伝性腎癌 / 環境発がん / ERC遺伝子 / Bhd遺伝子 / TSC遺伝子 / Niban遺伝子 / 腎発癌 / 肝癌 / 慢性肝炎 / 緩和ケア / 対話学 / 生死観の教育 / がん哲学外来 / がん教育 / 死生観の教育 / environmental carcinogenesis / VB-1 / inflammation / multistep carcinogenesis / hepatocarcinogenesis / chronic hepatitis / HCV / HBV / 肝がん / dhpA / 高がん化状態 / YB-1 / VR-1 / 炎症 / 肝発がん / hereditary cancer / Ere gene / Bhd gene / Tsc2遺伝子 / Tsc1遺伝子 / 腎発がん / 起始遺伝子 / Erc遺伝子 / Rapamycin / mTOR / Erc gene / Anima model / TSCI gene / Human tuberous sclerosis / Multistage carcinogenesis / Tsc2 gene / Hereditary renal carcinoma / Canier Genetics / wilms腫瘍 / 胸腺腫 / 前立腺癌 / 腎癌 / ラット発癌 / BUF / ラットゲノム / Mnaラット / BUM / LECラット / 癌感受性遺伝子 / がん抑制遺伝子 / 結節性硬化症 / 遺伝性腎がん / Ekerラット / Renalcarcinogenesis / 初期化 / 遺伝学 / Tsc遺伝子 / ips化 / 遺伝子 / 再生医療 / 病理学 / 癌 / がん幹細胞 / Tsc変異体 / iPS化 / リプログラミング / 疾患モデル動物 / 発症前診断 / 中皮腫 / ナノマテリアル / アスベスト / がん研究と社会の接点 / 遺伝子発現 / 分子標的治療 / 癌化遺伝子 / 多段階発癌 / 癌遺伝子 / ノックアウトマウス / トランスジェニックマウス / Positinal cloning / gene mapping / 2 hit / Cancer syndrome / 遺伝性腎癌ラット / 分子病理学 / B型肝炎ウイルス / 癌関連遺伝子 / in vitro recombination / recombinogenic protein / DNA recombination / genomic instability / HBV DNA / 肝発癌 / 肝炎ウイルス … More
Except Principal Investigator
トランスジェニックマウス / 肝発癌 / がん抑制遺伝子 / がん遺伝子 / 発がん / Erc / 中皮腫 / シグナル伝達 / 実験動物 / 分子病理 / 顕在がん / 潜在がん / 前がん病変 / B型肝炎ウイルス / Y box binding protein / dbpA / X遺伝子 / エンハンサー / DNA再編成 / アスベスト / 画像診断 / バイオマーカー / ノックアウトマウス / GPIアンカー蛋白 / Tsc2遺伝子 / 結節性硬化症 / 腎癌 / 発癌 / ラット / 相同遺伝子組換え / 癌遺伝子 / 腫瘍DNAパネル / HypoMethylation / HyperMethylation / 超高感度定量 / 高感度定量 / 融解曲線解析 / リアルタイムPCR / メチル化DNA / Mozaicism / Liquid biopsy / Hypomethylation / Hypermethylation / DNA メチル化 / SEPT9 / BRCA1 / MLH1 / 超高感度定量解析 / 高解像度融解曲線解析 / がん / リキッドバイオプシー / 大腸がん / 定量的超高感度解析 / DNAメチル化 / がん対策基本法 / 学習指導要領 / カルテット / 外部講師 / メディカルテット / 学校薬剤師 / がん教育 / 社会系心理学 / 癌 / 女性 / がんサバイバー / 子供の不安 / 母親の不安 / 気遣い / 母娘の関係性 / 女性がん患者の葛藤 / 死の受容 / がん終末期患者 / 被援助志向性 / 母親役割 / 女性がん患者 / genomic instability / hepatocarcinogenesis / 脂肪酸代謝 / アシルCoA合成酵素 / ゲノム不安定性 / Carcinogenesis / knockout mouse / GPI anchor protein / Tsc2 gene / Mesothelin gene / Erc遺伝子 / Mesothelin遺伝子 / PET / mesothelin / 腫瘍診断 / 悪性中皮腫 / Dysplasia / Neoplasia / Western blotting / Immunohistochemistry / Intracellular signal transduction / Tuberous sclerosis complex / 神経病理 / モデル動物 / 皮質結節 / 形成異常 / 過誤組織 / 腫瘍 / Westernブロッティング / 免疫組織化学 / 細胞内情報伝達 / Sanctity of Life / Spirituality / Religious Cultures / Enhancement / Embryonic Stem Cells / Cloning / Organ Transplantation / Brain Death / 生命科学 / 人工生殖 / クローン / 人胚研究 / いのち / インド / スリランカ / 死生観 / 国際宗教学宗教史学会 / 幹細胞 / 再生医療 / 生命倫理 / ヒトES細胞 / 生命倫理の日米比較 / 新生児集中治療 / 遺伝子治療 / インハーンスメント / スピリチュアルケア / ターミナルケア / 死 / <いのち>の尊厳 / スピリチュアリティ / 宗教文化 / エンハンスメント / ヒト胚性幹細胞 / クローン技術 / 臓器移植 / 脳死 / renal transplantaion / animal model / nephrogenic rest / Wilms tumor / WT1遺伝子 / 癌制御遺伝子 / 前癌病変 / 腎腫瘍 / WT1 / 前駆病変 / 化学発癌 / ENU / ウイルスム腫瘍 / 腎移植 / 動物モデル / ネフロジエ-ニック・レスト / ウィルムス腫瘍 / ウッドチャック肝炎ウイルス / 癌遺伝子1ca / cMyc遺伝子 / ウッドチャック肝癌 / ダックB型肝炎ウイルス / DNA組み込み / HBV / ウッドチャク肝炎ウイルス / Transgenic Mouse / 肝炎ウイルスエンハンサーlca遺伝子 / Transfection系 / ウッドチャック肝炎ウィルス / B型肝炎ウィルス / X抗原・抗体系 / 発癌遺伝子 / トランスフェクション / 染色体異常 / HBV DNA組込み / 肝細胞癌 / じん肺 / 石綿関連疾患 / コホート研究 / 検診 / 生化学マーカー / 胸部CT / 胸部エックス線 / 職業性呼吸器病 / マイクロアレイ / プロテオーム / プロテオミクス / 産業衛生 / Erc/mesothelin / がん分子標的薬剤 / ATL発症リスク / ATL発がん機序 / がん化学予防 / 分子疫学コーホート研究 / ATL発症予防 / 国際交流 / 個別化がん予防 / ゲノム・エピゲノム解析支援 / アカデミア創薬 / 次世代分子解析技術 / ゲノムコーホート研究 / 病理形態学 / 遺伝子改変マウス / 国際研究者交流 / 若手支援 / 2国間共同研究 / 2国間協同研究 / ヒトゲノム / がん転移 / DNA修復 / がん細胞 / PNUリンパ腫 / DMBA白血病 / ウイルソン病 / 肝炎肝癌 / LECラット / 腎臓 / Ekerラット / Eker / 癌抑制遺伝子 / N-ras / 遺伝子トラップ / 標的遺伝子組換え / LEC / 白血病 / mRNA / Nras / 遺伝子変異 / ES細胞 / 癌抑制院伝子 Less
  • Research Projects

    (44 results)
  • Research Products

    (269 results)
  • Co-Researchers

    (275 People)
  •  Development of cancer education system in cooperation with school pharmacists in the region

    • Principal Investigator
      Numata Chikako
    • Project Period (FY)
      2019 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 09040:Education on school subjects and primary/secondary education-related
    • Research Institution
      Kobe Pharmaceutical University
  •  Establishment of "cancer education and dialogue" based on "cancer philosophy"Principal Investigator

    • Principal Investigator
      Hino Okio
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Developmental mechanisms and the body works
    • Research Institution
      Juntendo University
  •  Psychological conflicts and decision making in explaining conditions to children of cancer survivors who have a mother's role

    • Principal Investigator
      Kurihara Akemi
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Lifelong developmental nursing
    • Research Institution
      Juntendo University
  •  Devolopment for highly sensitive and quantitative methods with a facile, fast and low-cost protocol.

    • Principal Investigator
      NOMURA Sachio
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Tumor diagnostics
    • Research Institution
      Japanese Foundation for Cancer Research
  •  Rehabilitation of cancer cellsPrincipal Investigator

    • Principal Investigator
      HINO Okio
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Experimental pathology
    • Research Institution
      Juntendo University
  •  Risk assessment of asbestos-related diseases among construction workers

    • Principal Investigator
      SUGANUMA Narufumi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hygiene
    • Research Institution
      Kochi University
  •  Rehabilitation of cancer cellsPrincipal Investigator

    • Principal Investigator
      HINO Okio
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Experimental pathology
    • Research Institution
      Juntendo University
  •  Scientific Support Programs for Cancer Research Grant-in-Aid for Scientific Research on Innovative Areas

    • Principal Investigator
      IMAI Kohzoh, 中村 祐輔
    • Project Period (FY)
      2010 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Research Institution
      The University of Tokyo
  •  Risk evaluation of environmental carcinogenesisPrincipal Investigator

    • Principal Investigator
      HINO Okio
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Cancer epidemiology and prevention
    • Research Institution
      Juntendo University
  •  The mechanism of loss of Erc gene ameliorates renal carcinogenesis and modulates integrin related pathway

    • Principal Investigator
      ZHANG Danqing
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory animal science
    • Research Institution
      Juntendo University
  •  Development of asbestos related tumor marker using protein array methods

    • Principal Investigator
      SUGANUMA Narufumi
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Hygiene
    • Research Institution
      Kochi University
  •  The functional analysis of Erc gene encoding GPI anchor protein

    • Principal Investigator
      ZHANG Danqing
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory animal science
    • Research Institution
      Juntendo University
  •  Role of dbpA in hepatocarcinogenesis

    • Principal Investigator
      KAJINO Kazunori
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Juntendo University
  •  The study of multistep carcinogenesis using unique animal modelsPrincipal Investigator

    • Principal Investigator
      HINO Okio
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Juntendo University
  •  Experimental pathologic study on the pathogenesis of cerebral lesions in tuberous sclerosis

    • Principal Investigator
      MIZUGUCHI Masashi
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Nerve anatomy/Neuropathology
    • Research Institution
      The University of Tokyo
  •  アスベスト暴露に伴う悪性中皮腫の早期診断法の開発

    • Principal Investigator
      辻井 博彦
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Special Purposes
    • Research Institution
      National Institute of Radiological Sciences
  •  Molecular mechanism of hypercarcinogenic state -inflammation-induced hepatocarcinogenesis-Principal Investigator

    • Principal Investigator
      HINO Okio
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      JUNTENDO UNIVERSITY
  •  Research on Brain Death and Organ Transplantation from the Perspective of Comparative Religion

    • Principal Investigator
      MACHIDA Soho
    • Project Period (FY)
      2002 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Religious studies
    • Research Institution
      Tokyo University of Foreign Studies
  •  Multi-step carcinogenesis using genetically retired modelsPrincipal Investigator

    • Principal Investigator
      HINO Okio
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Juntendo University School of Medfcine
      Japanese Foundation For Cancer Research
  •  ヨーロッパなどががん研究先進国との研究交流

    • Principal Investigator
      黒木 登志夫
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Field
      Experimental pathology
    • Research Institution
      Showa University
  •  Multistage carcinogenesis in TSC gene mutant modelsPrincipal Investigator

    • Principal Investigator
      HINO Okio
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Cancer Institute Carcinogenesis
  •  Pathogenesis of Human Tuberous SclerosisPrincipal Investigator

    • Principal Investigator
      HINO Okio
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      Cancer Institute
  •  ラット実験腫瘍の染色体遺伝子背景についての研究

    • Principal Investigator
      吉田 廸弘
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Hokkaido University
  •  遺伝性腎癌ラットの発癌機構の解明Principal Investigator

    • Principal Investigator
      樋野 興夫
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Japanese Foundation For Cancer Research
  •  Experimental study of Wilms tumor and its precursor lesion "nephrogenic rest" by using animal models.

    • Principal Investigator
      YOKOMORI Kinji
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      小児外科
    • Research Institution
      The University of Tokyo
  •  ラット実験腫瘍の染色体遺伝子背景についての研究

    • Principal Investigator
      杉山 武敏
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  化学発癌における前癌病変、潜在癌および顕在癌の特性に関する分子病理学的研究

    • Principal Investigator
      伊東 信行
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Nagoya City University
  •  遺伝子導入動物による発癌の研究Principal Investigator

    • Principal Investigator
      樋野 興夫
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Japanese Foundation For Cancer Research
  •  Isolation of the predisposing gene of the Eker rat model of hereditary renal cell carcinomaPrincipal Investigator

    • Principal Investigator
      HINO Okio
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Laboratory animal science
    • Research Institution
      Cancer Institute
  •  ラット実験腫瘍の染色体遺伝子背景についての研究

    • Principal Investigator
      杉山 武敏
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kyoto University
  •  遺伝子導入動物による発症の研究

    • Principal Investigator
      山村 研一
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kumamoto University
  •  化学発癌における前癌病変、潜在癌および顕在癌の特性に関する分子病理学的追求

    • Principal Investigator
      伊東 信行
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Nagoya City University
  •  遺伝性腎癌ラット繁殖システムの確立と発癌機構の解明Principal Investigator

    • Principal Investigator
      樋野 興夫
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Japanese Foundation For Cancer Research
  •  遺伝子導入動物による発癌の研究

    • Principal Investigator
      YAMAMURA Kenichi
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kumamoto University
  •  前癌病変、潜在癌および顕在癌の特性に関する分子病理学的追求

    • Principal Investigator
      伊東 信行
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Nagoya City University
  •  肝癌発生過程におけるgenomic instabilityの分子機構の解明Principal Investigator

    • Principal Investigator
      樋野 興夫
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      Japanese Foundation For Cancer Research
  •  肝炎ウイルスと肝癌発生

    • Principal Investigator
      服部 信
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kanazawa University
  •  B型肝炎ウイルスによる肝発癌の解析

    • Principal Investigator
      北川 知行
    • Project Period (FY)
      1987 – 1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Japanese Foundation For Cancer Research
  •  肝炎ウイルスと肝癌発生

    • Principal Investigator
      服部 信
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kanazawa University
  •  B型肝炎ウィルスによる肝発癌の解析

    • Principal Investigator
      北川 知行
    • Project Period (FY)
      1987 – 1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Japanese Foundation For Cancer Research
  •  B型肝炎ウイルスによる肝発癌の解析

    • Principal Investigator
      北川 知行
    • Project Period (FY)
      1987 – 1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Japanese Foundation For Cancer Research
  •  アメリカ大陸を中心としてがん研究先進グループとの研究交流

    • Principal Investigator
      河井 貞明
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Overseas Scientific Research
    • Research Institution
      The University of Tokyo
  •  B型肝炎ウイルスの宿主DNAへの組込みと肝癌発生

    • Principal Investigator
      服部 信
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kanazawa University
  •  B型肝炎ウイルスと肝発癌

    • Principal Investigator
      北川 知行
    • Project Period (FY)
      1984 – 1986
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      Japanese Foundation For Cancer Research

All 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 Other

All Journal Article Presentation Book Patent Other

  • [Book] われ21世紀の新渡戸とならん2018

    • Author(s)
      樋野 興夫
    • Total Pages
      93
    • Publisher
      イーグレープ
    • ISBN
      9784909170040
    • Data Source
      KAKENHI-PROJECT-16K12983
  • [Book] 楕円形のこころ2018

    • Author(s)
      樋野 興夫
    • Total Pages
      148
    • Publisher
      春秋社
    • ISBN
      4393716337
    • Data Source
      KAKENHI-PROJECT-16K12983
  • [Book] 大切な人ががんになったとき…生きる力を引き出す寄り添い方2018

    • Author(s)
      樋野興夫
    • Total Pages
      208
    • Publisher
      青春出版社
    • ISBN
      4413211146
    • Data Source
      KAKENHI-PROJECT-16K12983
  • [Book] 苦しみを癒す「無頓着」のすすめ2017

    • Author(s)
      樋野 興夫
    • Total Pages
      212
    • Publisher
      ブックマン社
    • ISBN
      9784893088758
    • Data Source
      KAKENHI-PROJECT-16K12983
  • [Book] 人の心に贈り物を残していく2017

    • Author(s)
      樋野興夫、柳田邦男
    • Total Pages
      256
    • Publisher
      悟空出版
    • ISBN
      9784908117336
    • Data Source
      KAKENHI-PROJECT-16K12983
  • [Book] いい人生は、最期の5年で決まる2017

    • Author(s)
      樋野 興夫
    • Total Pages
      176
    • Publisher
      SBクリエイティブ
    • ISBN
      9784797389616
    • Data Source
      KAKENHI-PROJECT-16K12983
  • [Book] 人生から期待される生き方2017

    • Author(s)
      樋野興夫
    • Total Pages
      208
    • Publisher
      主婦の友社
    • ISBN
      9784074229079
    • Data Source
      KAKENHI-PROJECT-16K12983
  • [Book] がんばりすぎない、悲しみすぎない。 「がん患者の家族」のための言葉の処方箋2017

    • Author(s)
      樋野 興夫
    • Total Pages
      194
    • Publisher
      講談社
    • ISBN
      9784062206150
    • Data Source
      KAKENHI-PROJECT-16K12983
  • [Book] 「がん哲学外来へようこそ」2016

    • Author(s)
      樋野興夫
    • Total Pages
      192
    • Publisher
      新潮社
    • Data Source
      KAKENHI-PROJECT-16K12983
  • [Book] 「あなたはそこにいるだけで価値ある存在」2016

    • Author(s)
      樋野興夫
    • Total Pages
      207
    • Publisher
      KADOKAWA
    • Data Source
      KAKENHI-PROJECT-16K12983
  • [Book] 「今日」という日の花を摘む2016

    • Author(s)
      樋野興夫
    • Total Pages
      256
    • Publisher
      実業之日本社
    • Data Source
      KAKENHI-PROJECT-16K12983
  • [Book] 「病気は人生の夏休み」2016

    • Author(s)
      樋野興夫
    • Total Pages
      199
    • Publisher
      幻冬舎
    • Data Source
      KAKENHI-PROJECT-16K12983
  • [Book] Models for genitourinary cancer-Hereditary renal carcinogenesis. The CANCER handbook. Second edition.2007

    • Author(s)
      Hino, O.
    • Publisher
      WILEY
    • Data Source
      KAKENHI-PROJECT-17013076
  • [Book] Cancer : Cell Structures, Carcinogens and Genomic Instability.2006

    • Author(s)
      Hino O., Kobayashi T., Okimoto K.
    • Total Pages
      24
    • Publisher
      Birkhauser Verlag
    • Data Source
      KAKENHI-PROJECT-17013076
  • [Book] In New Perspectives in Cancer Research and Therapy. (Edited Shigeki Kuriyama and Hitoshi Yoshiji)2005

    • Author(s)
      Hino O.
    • Publisher
      Research Signpost
    • Data Source
      KAKENHI-PROJECT-16390121
  • [Book] New Perspectives in Cancer Research and Therapy2005

    • Author(s)
      Hino, O.
    • Total Pages
      6
    • Publisher
      Research Signpost
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390121
  • [Book] Cancer : Cell Structures, Carinogenes and Genomic Instability.2005

    • Author(s)
      Hino O., Kobayashi T., Okimoto K.
    • Publisher
      Birkhauser Verlag
    • Data Source
      KAKENHI-PROJECT-17013076
  • [Book] Gann Monograph on Cancer Research2004

    • Author(s)
      Hino O.et al.
    • Total Pages
      15
    • Publisher
      2004 Japan Scientific Societies Press.
    • Data Source
      KAKENHI-PROJECT-12213139
  • [Book] Philosophy of Cancer : Viewing the Conditions of Human Society from the Cancer Cell2004

    • Author(s)
      Okio Hino
    • Total Pages
      106
    • Publisher
      to be shuppan
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14310014
  • [Book] がん哲学 がん細胞から人間社会の病理を見る2004

    • Author(s)
      樋野興夫
    • Total Pages
      106
    • Publisher
      to be出版
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14310014
  • [Book] がん哲学 がん細胞から人間社会の病理を見る2004

    • Author(s)
      樋野 興夫
    • Total Pages
      106
    • Publisher
      to be 出版
    • Data Source
      KAKENHI-PROJECT-14310014
  • [Book] Gann Monograph on Cancer Research2004

    • Author(s)
      Hino O.et al.
    • Total Pages
      15
    • Publisher
      2004 Japan Scientific Societies Press.
    • Data Source
      KAKENHI-PROJECT-16390121
  • [Journal Article] Psychological transition characteristics of patients diagnosed with asbestos-related mesothelioma.2018

    • Author(s)
      Kasai Y., Hino O.
    • Journal Title

      Juntendo Medical Journal

      Volume: 64 Pages: 114-121

    • NAID

      130007397832

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K12983
  • [Journal Article] The Effects of URAT1/SLC22A12 Nonfunctional Variants, R90H and W258X, on Serum Uric Acid Levels and Gout/hyperuricemia Progression2016

    • Author(s)
      Sakiyama M, Matsuo H, Shimizu S et al.
    • Journal Title

      Sci Rep

      Volume: 6 Issue: 1 Pages: 20148-20148

    • DOI

      10.1038/srep20148

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26461244, KAKENHI-PROJECT-15K15227, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-25293145, KAKENHI-PROJECT-15H04315, KAKENHI-PROJECT-16K10181
  • [Journal Article] Clinical impacts of mesothelin expression in gastrointestinal carcinomas.2016

    • Author(s)
      Einama T., Kawamata F., Kamachi H., Nishihara H., Homma S., Matsuzawa F., Mizukami T., Konishi Y., Tahara M., Kamiyama T., Hino O., Taketomi A., Todo S.
    • Journal Title

      World J. Gastrointestinal Pathophysiology

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] The relationship between EZH2 expression and microRNA-31 in colorectal cancer and the role in evolution of the serrated pathway.2016

    • Author(s)
      Kurihara H, Maruyama R, Ishiguro K, Kanno S, Yamamoto I, Ishigami K, Mitsuhashi K, Igarashi H, Ito M, Tanuma T, Sukawa Y, Okita K, Hasegawa T, Imai K, Yamamoto H, Shinomura Y, Nosho K.
    • Journal Title

      Oncotarget

      Volume: 7 Issue: 11 Pages: 12704-12717

    • DOI

      10.18632/oncotarget.7260

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K14397, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-26640101, KAKENHI-PROJECT-16K07145, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-16H06297
  • [Journal Article] Association of Fusobacterium nucleatum with immunity and molecular alterations in colorectal cancer.2016

    • Author(s)
      Nosho K, Sukawa Y, Adachi Y, Ito M, Mitsuhashi K, Kurihara H, Kanno S, Yamamoto I, Ishigami K, Igarashi H, Maruyama R, Imai K, Yamamoto H, Shinomura Y.
    • Journal Title

      World J Gastroenterol

      Volume: 22 Issue: 2 Pages: 557-566

    • DOI

      10.3748/wjg.v22.i2.557

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K14397, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-26640101, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-16H06297
  • [Journal Article] Changes of tryptophan metabolism in Japanese runners during an ultramarathon race.2016

    • Author(s)
      Yamada N, Shibata K, Fuku M, Kuriki K, Goto G, Tokudome Y, Miyata M, Maeda K, Hoshino H, Suzuki S, Marumoto M, Ichikawa H, Agawa H, Ishikawa N, Arakawa K, Hosono A, Kobayashi M, Tokudome S.
    • Journal Title

      Sport Sci Health

      Volume: 12 Issue: 1 Pages: 77-83

    • DOI

      10.1007/s11332-016-0257-1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] Association of microRNA-31-5p with clinical efficacy of anti-EGFR therapy in patients with metastatic colorectal cancer2015

    • Author(s)
      Igarashi H, Kurihara H, Mitsuhashi K, Ito M, Okuda H, Kanno S, Naito T, Yoshii S, Takahashi H, Kusumi T, Hasegawa T, Sukawa Y, Adachi Y, Okita K, Hirata K, Imamura Y, Baba Y, Imai K, Suzuki H, Yamamoto H, Nosho K, Shinomura Y
    • Journal Title

      Ann Surg Oncol

      Volume: 14 Issue: 8 Pages: 4264-4267

    • DOI

      10.1245/s10434-014-4264-7

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25670371, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-26640101, KAKENHI-PROJECT-26293290
  • [Journal Article] Rheb activation disrupts spine synapse formation through accumulation of syntenin in tuberous sclerosis complex2015

    • Author(s)
      Hiroko Sugiura, Shin Yasuda, Shutaro Katsurabayashi, Hiroyuki Kawano, Kentaro Endo, Kotaro Takasaki, Katsunori Iwasaki, Masumi Ichikawa, Toshiyuki Kobayashi, Okio Hino and Kanato Yamagata
    • Journal Title

      Nature Communications

      Volume: 6 Issue: 1 Pages: 6842-6842

    • DOI

      10.1038/ncomms7842

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24659093, KAKENHI-PUBLICLY-25110737, KAKENHI-PROJECT-25293239, KAKENHI-PROJECT-25350988, KAKENHI-PROJECT-25670196, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-24500452
  • [Journal Article] Environmental carcinognensis-100th anniversary of creating cancer.2015

    • Author(s)
      Misa Imai, Okio Hino
    • Journal Title

      Cancer Science

      Volume: 106 Issue: 11 Pages: 1483-1485

    • DOI

      10.1111/cas.12798

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26861341, KAKENHI-PROJECT-221S0001
  • [Journal Article] Contextual niche signals towards colorectal tumor progression by mesenchymal stem cell in the mouse xenograft model2015

    • Author(s)
      Nakagaki S, Arimura Y, Nagaishi K, Isshiki H, Nasuno M, Watanabe S, Idogawa M, Yamashita K, Naishiro Y, Adachi Y, Suzuki H, Fujimiya M, Imai K, Shinomura Y
    • Journal Title

      J Gastroenterol

    • Description
      【掲載確定】 Epub ahead of print
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] Common variant of ALPK1 is not associated with gout: a replication study.2015

    • Author(s)
      Chiba T, Matsuo H, et al.
    • Journal Title

      Hum Cell

      Volume: 28 Issue: 1 Pages: 1-4

    • DOI

      10.1007/s13577-014-0103-1

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25670307, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-15K15227, KAKENHI-PROJECT-15H04315, KAKENHI-PROJECT-25293145
  • [Journal Article] Low FOXA1 expression predicts good response to neo-adjuvant chemotherapy resulting in good outcomes for luminal HER2-negative breast cancer cases2015

    • Author(s)
      Horimoto, Y., Arakawa A., Harada-Shoji N., Sonoue H., Yoshida Y., Himuro T., Igari F., Tokuda E., Mamat O., Tanabe M., Hino O. and Saito M.
    • Journal Title

      Br J Cancer

      Volume: 112 Issue: 2 Pages: 345-351

    • DOI

      10.1038/bjc.2014.595

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] Analysis of the molecular features of rectal carcinoid tumors to identify new biomarkers that predict biological malignancy2015

    • Author(s)
      Mitsuhashi K, Yamamoto I, Kurihara H, Kanno S, Ito M, Igarashi H, Ishigami K, Sukawa Y, Tachibana M, Takahashi H, Tokino T, Maruyama R, Suzuki H, Imai K, Shinomura Y, Yamamoto H, Nosho K
    • Journal Title

      ONCOTARGET

      Volume: 6 Issue: 26 Pages: 22114-22125

    • DOI

      10.18632/oncotarget.4294

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25430115, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-26640101
  • [Journal Article] Minimal inflammogenicity of pristine single-wall carbon nanotubes.2015

    • Author(s)
      Toyokuni S, Jiang L, Kitaura R and Shinohara S.
    • Journal Title

      Nagoya J Med Sci

      Volume: 77 Pages: 195-202

    • NAID

      120005549565

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] Cotyledonoid dissecting leiomyoma of the uterus : report of two cases2015

    • Author(s)
      Saeki, H., Suzuki C., Yamasaki S., Hashizume A., Izumi H., Suzuki F., Ishi K., Nojima M. and Hino O.
    • Journal Title

      Arch Gynecol Obstet

      Volume: 291 Issue: 2 Pages: 357-361

    • DOI

      10.1007/s00404-014-3406-2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] NPT1/SLC17A1 is a renal urate exporter in humans and its common gain-of-function variant decreases the risk of renal underexcretion gout.2015

    • Author(s)
      Chiba T, Matsuo H, Kawamura Y, Nagamori S, Nishiyama T, Wei L, Nakayama A, Nakamura T, Sakiyama M, Takada T, Taketani Y, Suma S, Naito M, Oda T, Kumagai H, Moriyama Y, Ichida K, Shimizu T, Kanai Y, Shinomiya N.
    • Journal Title

      Arthritis Rheumatol.

      Volume: 67(1) Issue: 1 Pages: 281-287

    • DOI

      10.1002/art.38884

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-23590702, KAKENHI-PROJECT-23689008, KAKENHI-PROJECT-24390217, KAKENHI-PROJECT-24591198, KAKENHI-PUBLICLY-25136714, KAKENHI-PROJECT-25293145, KAKENHI-PROJECT-25670307, KAKENHI-PROJECT-26461244, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-15H04315, KAKENHI-PROJECT-25253008
  • [Journal Article] Low-frequency IL23R coding variant associated with Crohn's disease susceptibility in Japanese subjects identified by personal genomics analysis2015

    • Author(s)
      Onodera K, Arimura Y, Isshiki H, Kawakami K, Nagaishi K, Yamashita K, Yamamoto E, Niinuma T, Naishiro Y, Suzuki H, Imai K, Shinomura Y
    • Journal Title

      PLoS ONE

      Volume: 10 Issue: 9 Pages: e0137801-e0137801

    • DOI

      10.1371/journal.pone.0137801

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08972, KAKENHI-PROJECT-15K08973, KAKENHI-PROJECT-26460975, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-25460954, KAKENHI-PROJECT-25460955, KAKENHI-PROJECT-26640101
  • [Journal Article] Clinicopathological and molecular characteristics of serrated lesions in Japanese elderly patients2015

    • Author(s)
      Nosho K, Igarashi H, Ito M, Mitsuhashi K, Kurihara H, Kanno S, Yoshii S, Mikami M, Takahashi H, Kusumi T, Hosokawa M, Sukawa Y, Adachi Y, Hasegawa T, Okita K, Hirata K, Maruyama R, Suzuki H, Imai K, Yamamoto H, Shinomura Y
    • Journal Title

      Digestion

      Volume: 91(1) Issue: 1 Pages: 57-63

    • DOI

      10.1159/000368820

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26640101, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-25293289
  • [Journal Article] Transgenic mouse model for imaging of interleukin-1β-related inflammation in vivo.2015

    • Author(s)
      Iwawaki T, Akai R, Oikawa D, Toyoshima T, Yoshino M, Suzuki M, Takeda N, Ishikawa T, Kataoka Y, Yamamura K.
    • Journal Title

      Scientific Reports.

      Volume: 5 Issue: 1 Pages: 17205-17205

    • DOI

      10.1038/srep17205

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08259, KAKENHI-PUBLICLY-15H00905, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-25460399
  • [Journal Article] Epigenetic silencing of NTSR1 is associated with lateral and noninvasive growth of colorectal tumors2015

    • Author(s)
      Kamimae S, Yamamoto E, Kai M, Niinuma T, Yamano HO, Nojima M, Yoshikawa K, Kimura T, Takagi R, Harada E, Harada T, Maruyama R, Sasaki Y, Tokino T, Shinomura Y, Sugai T, Imai K, Suzuki H
    • Journal Title

      Oncotarget

      Volume: 6 Issue: 30 Pages: 29975-90

    • DOI

      10.18632/oncotarget.5034

    • NAID

      130005161526

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08973, KAKENHI-PROJECT-25430115, KAKENHI-PROJECT-26460944, KAKENHI-PROJECT-15K15584, KAKENHI-PROJECT-15K18431, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-15H04299, KAKENHI-PROJECT-25460420, KAKENHI-PROJECT-26640101
  • [Journal Article] Association of Fusobacterium species in pancreatic cancer tissues with molecular features and prognosis2015

    • Author(s)
      Mitsuhashi K, Nosho K, Sukawa Y, Matsunaga Y, Ito M, Kurihara H, Kanno S, Igarashi H, Naito T, Adachi Y, Tachibana M, Tanuma T, Maguchi H, Shinohara T, Hasegawa T, Imamura M, Kimura Y, Hirata K, Maruyama R, Suzuki H, Imai K, Yamamoto H, Shinomura Y
    • Journal Title

      Oncotarget

    • Description
      【掲載確定】 in press
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] A potential function for neuronal exosomes: sequestering intracerebral amyloid-beta peptide.2015

    • Author(s)
      Yuyama, K., Sun, H., Usuki, S., Sakai, S., Hanamatsu, H., Mioka, T., Kimura, N., Okada, M., Tahara, H., Furukawa, J., Fujitani, N., Shinohara, Y. & Igarashi, Y.
    • Journal Title

      FEBS letters

      Volume: 589 Issue: 1 Pages: 84-88

    • DOI

      10.1016/j.febslet.2014.11.027

    • NAID

      120005537475

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-25112711, KAKENHI-PROJECT-25290039, KAKENHI-PROJECT-26290047, KAKENHI-PROJECT-26310106, KAKENHI-PROJECT-26640091, KAKENHI-PROJECT-221S0001
  • [Journal Article] Establishiment of Tsc2-deficient rat embryonic stem cells.2015

    • Author(s)
      Ito Y., Kawano H., Kanai F., Nakamura E., Tada N., Takai S., Horie S., Arai H., Kobayashi T. & Hino O.
    • Journal Title

      Int. J. Oncology

      Volume: 46 Issue: 5 Pages: 1944-1952

    • DOI

      10.3892/ijo.2015.2913

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25670196, KAKENHI-PROJECT-26460398, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-26430207
  • [Journal Article] Association of Fusobacterium nucleatum with clinical and molecular features in colorectal serrated pathway.2015

    • Author(s)
      Ito M, Kanno S, Nosho K, Sukawa Y, Mitsuhashi K, Kurihara H, Igarashi H, Takahashi T, Tachibana M, Takahashi H, Yoshii S, Takenouchi T, Hasegawa T, Okita K, Hirata K, Maruyama R, Suzuki H, Imai K, Yamamoto H, Shinomura Y.
    • Journal Title

      Int J Cancer

      Volume: 137 Issue: 6 Pages: 1258-1268

    • DOI

      10.1002/ijc.29488

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K14397, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-15H04299, KAKENHI-PROJECT-26640101
  • [Journal Article] Role of interleukin-32 in the mechanism of chronic inflammation in IgG4-related disease and as a predictive biomarker for drug-free remission.2015

    • Author(s)
      Shimizu Y, Yamamoto M, Yajima H, Suzuki C, Naishiro Y, Takahashi H, Imai K, Shinomura Y.
    • Journal Title

      Modern Rheumatology

      Volume: 26(3) Pages: 391-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] Cancer Philosophy~Thinking“Cancer Cells”Deeply2014

    • Author(s)
      Hino, O
    • Journal Title

      Juntendo Medical Journal

      Volume: 60

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] Ethnic Differences in ATP-binding Cassette Transporter, Sub-family G, Member 2 (ABCG2/BCRP): Genotype Combinations and Estimated Functions2014

    • Author(s)
      Sakiyama M, et al.
    • Journal Title

      Drug Metabolism and Pharmacokinetics

      Volume: 29 Issue: 6 Pages: 490-492

    • DOI

      10.2133/dmpk.DMPK-14-SC-041

    • NAID

      130004463408

    • ISSN
      1347-4367, 1880-0920
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23689008, KAKENHI-PROJECT-25293145, KAKENHI-PROJECT-25670307, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-221S0002
  • [Journal Article] Everyday clinical practice in IgG4-related dacryoadenitis and/or sialadenitis: Results from the SMART database.2014

    • Author(s)
      Yamamoto M, Yajima H, Takahashi H, Yokoyama Y, Ishigami K, Shimizu Y, Tabeya T, Suzuki C, Naishiro Y, Takano KI, Yamashita K, Hashimoto M, Keira Y, Honda S, Abe T, Suzuki Y, Mukai M,Himi T, Hasegawa T, Imai K, Shinomura Y
    • Journal Title

      Mod Rheumatol

      Volume: 27 Issue: 2 Pages: 1-6

    • DOI

      10.3109/14397595.2014.950036

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25861575, KAKENHI-PROJECT-15K10818, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-26640101
  • [Journal Article] Activation of Rheb, but not of mTORC1, impairs spine synapse morphogenesis in tuberous sclerosis complex.2014

    • Author(s)
      Yasuda S, Sugiura H, Katsurabayashi S, Shimada T, Tanaka H, Takasaki K, Iwasaki K, Kobayashi T, Hino O, Yamagata K.
    • Journal Title

      Sci Rep.

      Volume: 4 Issue: 1 Pages: 5155-5155

    • DOI

      10.1038/srep05155

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23590300, KAKENHI-PROJECT-24500452, KAKENHI-PROJECT-24659093, KAKENHI-PROJECT-24700349, KAKENHI-PUBLICLY-25110737, KAKENHI-PROJECT-25293239, KAKENHI-PROJECT-25350988, KAKENHI-PROJECT-25670196, KAKENHI-PROJECT-221S0001
  • [Journal Article] The effect of IGF-I receptor blockade for human esophageal squamous cell carcinoma and adenocarcinoma2014

    • Author(s)
      Adachi Y, Ohashi H, Imsumran A, Yamamoto H, Matsunaga Y, Taniguchi H, Nosho K, Suzuki H, Sasaki Y, Arimura Y, Carbone DP, Imai K, Shinomura Y
    • Journal Title

      Tumour Biol

      Volume: 35 Issue: 2 Pages: 973-985

    • DOI

      10.1007/s13277-013-1131-2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23240129, KAKENHI-PROJECT-23390200, KAKENHI-PROJECT-23590920, KAKENHI-PROJECT-24650632, KAKENHI-PROJECT-26640101, KAKENHI-PROJECT-221S0001
  • [Journal Article] Iron and thiols as two major players in carcinogenesis : friends or foes?2014

    • Author(s)
      Toyokuni, S.
    • Journal Title

      Front Pharmacol

      Volume: 5

    • DOI

      10.3389/fphar.2014.00200

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] Epstein-Barr Virus-infected Cells in IgG4-related Lymphadenopathy With Comparison With Extranodal IgG4-related Disease.2014

    • Author(s)
      Takeuchi M, Sato Y, Yasui H, Ozawa H, Ohno K, Takata K, Gion Y, Orita Y, Tachibana T, Itoh T, Asano N, Nakamura S, Swerdlow SH, Yoshino T.
    • Journal Title

      Am J Surg Pathol.

      Volume: - Issue: 7 Pages: 946-955

    • DOI

      10.1097/pas.0000000000000206

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591402, KAKENHI-PROJECT-24591447, KAKENHI-PROJECT-26293078, KAKENHI-PROJECT-26640101, KAKENHI-PROJECT-221S0001
  • [Journal Article] Newly established ELISA for N-ERC/mesothelin improves diagnostic accuracy in patients with suspected pleural mesothelioma2014

    • Author(s)
      Sato, T., Suzuki Y., Mori T., Maeda M., Abe M., Hino O. and Takahashi K.
    • Journal Title

      Cancer Med

      Volume: 3 Issue: 5 Pages: 1377-1384

    • DOI

      10.1002/cam4.297

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] Burden of total and cause-specific mortality related to tobacco smoking among adults aged ≥ 45 years in Asia : a pooled analysis of 21 cohorts2014

    • Author(s)
      Zheng, W., McLerran D.F., Rolland B.A., Fu Z., Boffetta P., Tsugane S., Irie F., Tamakoshi A., Shu X.O., Ozasa K., Nishino Y., Tsuji I., Tanaka H., Sawada N., Ohishi W., Kakizaki M., Watanabe T., Oze I., Sugawara Y., Matsuo K., et al.
    • Journal Title

      PLoS Med

      Volume: 11 Issue: 4 Pages: e1001631-e1001631

    • DOI

      10.1371/journal.pmed.1001631

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] Identification of immunogenic LY6K long peptide encompassing both CD4+ and CD8+ T-cell epitopes and eliciting CD4+ T-cell immunity in patients with malignant disease.2014

    • Author(s)
      Tomita, Y., Yuno, A., Tsukamoto, H., Senju, S., Kuroda, Y., Hirayama, M., Imamura, Y., Yatsuda, J., Sayem, M. A., Irie, A., Hamada A., Jono, H., Yoshida, K., Tsunoda, T, Daigo, Y., Kohrogi, H., Yoshitake, Y., Nakamura,Y., Shinohara, M. and Nishimura, Y.
    • Journal Title

      OncoImmunology

      Volume: 3 Issue: 3 Pages: e28100-e28100

    • DOI

      10.4161/onci.28100

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22133005, KAKENHI-PROJECT-24300334, KAKENHI-PROJECT-26460972, KAKENHI-PROJECT-221S0001
  • [Journal Article] Transgenic expression of the N525S-tuberin variant in Tsc2 mutant (Eker) rats causes dominant embryonic lethality.2014

    • Author(s)
      Shiono M., Kobayashi T., Takahashi R., Ueda M., Ishikawa C. and Hino O.
    • Journal Title

      Scientific Reports

      Volume: 4 Issue: 1 Pages: 5927-5927

    • DOI

      10.1038/srep05927

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670196, KAKENHI-PROJECT-221S0001
  • [Journal Article] Association of microRNA-31-5p with clinical efficacy of anti-EGFR therapy in patients with metastatic colorectal cancer2014

    • Author(s)
      Igarashi H, Kurihara H, Mitsuhashi K, Ito M, Okuda H, Kanno S, Naito T, Yoshii S, Takahashi H, Kusumi T, Hasegawa T, Sukawa Y, Adachi Y, Okita K, Hirata K, Imamura Y, Baba Y, Imai K, Suzuki H, Yamamoto H, Nosho K, Shinomura Y
    • Journal Title

      Annals of Surgical Oncology

    • Description
      Epub ahead of print
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] Asbestos-related mesothelioma : Prevention, early detection, treatment2014

    • Author(s)
      Imai, M. and Hino O.
    • Journal Title

      JSM Clinical Oncology and Research

      Volume: 2 Issue: 3

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] Coffee and green tea consumption is associated with upper aerodigestive tract cancer in Japan2014

    • Author(s)
      Oze I, Matsuo K, Kawakita D, Hosono S, Ito H, Watanabe M, Hatooka S, Hasegawa Y, Shinoda M, Tajima K, Tanaka H.
    • Journal Title

      International journal of cancer

      Volume: 135 Issue: 2 Pages: 391-400

    • DOI

      10.1002/ijc.28653

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26860430, KAKENHI-PROJECT-221S0001
  • [Journal Article] Mesenchymal stem cells cancel azoxymethane-induced tumor initiation2014

    • Author(s)
      Nasuno M, Arimura Y, Nagaishi K, Isshiki H, Onodera K, Nakagaki S, Watanabe S, Idogawa M, Yamashita K, Naishiro Y, Adachi Y, Suzuki H, Fujimiya M, Imai K, Shinomura Y
    • Journal Title

      Stem Cells

      Volume: 32 Issue: 4 Pages: 913-925

    • DOI

      10.1002/stem.1594

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23240129, KAKENHI-PROJECT-24650632, KAKENHI-PROJECT-25460929, KAKENHI-PROJECT-25460954, KAKENHI-PROJECT-25460955, KAKENHI-PROJECT-26640101, KAKENHI-PROJECT-221S0001
  • [Journal Article] A common variant of organic anion transporter 4(OAT4/SLC22A11) gene is associated with renal underexcretion type gout2014

    • Author(s)
      Sakiyama, M., Matsuo H., Shimizu S., Nakashima H., Nakayama A., Chiba T., Naito M., Takada T., Suzuki H., Hamajima N., Ichida K., Shimizu T. and Shinomiya N.
    • Journal Title

      Drug Metab Pharmacokinet

      Volume: 29

    • NAID

      130004463357

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] Retrospective analysis of large-scale research screening of construction workers for the early diagnosis of mesothelioma.2014

    • Author(s)
      Hirohashi T, Igarashi K, Abe M, Hino O et al.
    • Journal Title

      Molecular and clinical oncology

      Volume: 2 Issue: 1 Pages: 26-30

    • DOI

      10.3892/mco.2013.197

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] Radiographic Progression of Silicosis among Japanese Tunnel Workers in Kochi.2014

    • Author(s)
      Narongpon Dumavibhat, Tomomi Matsui, Eri Hoshino, Sasivimol Rattanasiri, Dittapol Muntham, Ryoji Hirota, Masamitsu Eitoku, Momo Imanaka, Basilua Andre Muzembo, Nlandu Roger Ngatu, Shinichi Kondo, Norihiko Hamada, Narufumi Suganuma
    • Journal Title

      Journal of Occupational Health

      Volume: -

    • NAID

      10031159406

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390154
  • [Journal Article] MicroRNA-31 expression in relation to BRAF mutation, CpG island methylation and colorectal continuum in serrated lesions2014

    • Author(s)
      Ito M, Mitsuhashi K, Igarashi H, Nosho K, Yamamoto H
    • Journal Title

      Int J Cancer

      Volume: (Epub ahead of print) Issue: 11 Pages: 2507-2515

    • DOI

      10.1002/ijc.28920

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23300366, KAKENHI-PROJECT-23590920, KAKENHI-PUBLICLY-25134715, KAKENHI-PROJECT-25430115, KAKENHI-PROJECT-25461705, KAKENHI-PROJECT-26460944, KAKENHI-PROJECT-26640101, KAKENHI-PROJECT-221S0001
  • [Journal Article] C-ERC/mesothelin provokes lymphatic invasion of colorectal adenocarcinoma2014

    • Author(s)
      Kawamata F, Homma S, Kamachi H, Einama T, Kato Y, Tsuda M, Tanaka S, Maeda M, Kajino K, Hino O, Takahashi N, Kamiyama T, Nishihara H, Taketomi A, Todo S
    • Journal Title

      J Gastroenterology

      Volume: 49 Issue: 1 Pages: 81-92

    • DOI

      10.1007/s00535-013-0773-6

    • NAID

      120005537455

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590435, KAKENHI-PROJECT-24590469, KAKENHI-PROJECT-221S0001
  • [Journal Article] Decreased amyloid-beta pathologies by intracerebral loading of glycosphingolipid-enriched exosomes in Alzheimer model mice.2014

    • Author(s)
      Yuyama, K., Sun, H., Sakai, S., Mitsutake, S., Okada, M., Tahara, H., Furukawa, J., Fujitani, N., Shinohara, Y. & Igarashi, Y.
    • Journal Title

      J Biol Chem

      Volume: 289 Issue: 35 Pages: 24488-24498

    • DOI

      10.1074/jbc.m114.577213

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-25112711, KAKENHI-PROJECT-26290047, KAKENHI-PROJECT-26310106, KAKENHI-PROJECT-26440041, KAKENHI-PROJECT-26450162, KAKENHI-PROJECT-26640091, KAKENHI-PROJECT-221S0001
  • [Journal Article] Utility of PAX8 mouse monoclonal antibody in the diagnosis of thyroid, thymic, pleural, and lung tumors: a comparison with polyclonal PAX8 antibody.2014

    • Author(s)
      Toriyama A, Mori T, Sekine S, Yoshida A, Hino O, Tsuta K.
    • Journal Title

      Histopathology

      Volume: On line Issue: 4 Pages: 465-72

    • DOI

      10.1111/his.12405

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390469, KAKENHI-PROJECT-25670868, KAKENHI-PROJECT-26460463, KAKENHI-PROJECT-221S0001
  • [Journal Article] Rat N-ERC/mesothelin as a marker for in vivo screening of drugs against pancreas cancer2014

    • Author(s)
      Fukamachi K, Iigo M, Hagiwara Y, Shibata K, Futakuchi M, Alexander DB, Hino O, Suzui M, Tsuda H.
    • Journal Title

      PLoS One

      Volume: 9 Issue: 10 Pages: 268-274

    • DOI

      10.1371/journal.pone.0111481

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-23590469, KAKENHI-PROJECT-24501319, KAKENHI-PROJECT-25430154, KAKENHI-PROJECT-26460476, KAKENHI-PROJECT-221S0001
  • [Journal Article] Database for exchangeable gene trap clones: Pathway and gene ontology analysis of exchangeable gene trap clone mouse lines.2014

    • Author(s)
      Araki, M., Nakahara, M., Muta, M., Itou, M., Yanai, C., Yamazoe, F., Miyake, M., Morita, A., Araki, M., Okamoto, Y., Nakagata, M., Yoshinobu, K., Yamamura, K. and Araki, K.
    • Journal Title

      Develop. Growth Differ.

      Volume: 56 Issue: 2 Pages: 161-174

    • DOI

      10.1111/dgd.12116

    • NAID

      40019987325

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-23310135, KAKENHI-PROJECT-25430092, KAKENHI-PROJECT-221S0001
  • [Journal Article] Analysis of DNA methylation in bowel lavage fluid for detection of colorectal cancer.2014

    • Author(s)
      Harada T, Yamamoto E, Yamano HO, Nojima M, Maruyama R, Kumegawa K, Ashida M, Yoshikawa K, Kimura T, Harada E, Takagi R, Tanaka Y, Aoki H, Nishizono M, Nakaoka M, Tuyada A, Niinuma T, Kai M, Shimoda K, Shinomura Y, Sugai T, Imai K, Suzuki H.
    • Journal Title

      Cancer Prev Res (Phila)

      Volume: 7(10) Issue: 10 Pages: 1002-1010

    • DOI

      10.1158/1940-6207.capr-14-0162

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461705, KAKENHI-PROJECT-26640101, KAKENHI-PROJECT-221S0001
  • [Journal Article] IGF2 differentially methylated region hypomethylation in relation to pathological and molecular features of serrated lesions2014

    • Author(s)
      Naito T, Nosho K, Ito M, Igarashi H, Mitsuhashi K, Yoshii S, Aoki H, Nomura M, Sukawa Y, Yamamoto E, Adachi Y, Takahashi H, Hosokawa M, Fujita M, Takenouchi T, Maruyama R, Suzuki H, Baba Y, Imai K, Yamamoto H, Ogino S, Shinomura Y.
    • Journal Title

      World J Gastroenterol

      Volume: 20(29) Issue: 29 Pages: 10050-61

    • DOI

      10.3748/wjg.v20.i29.10050

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26640101, KAKENHI-PROJECT-221S0001
  • [Journal Article] Tumor-derived Interleukin-1 promotes lymphangiogenesis and lymph node metastasis through M2-type macrophages2014

    • Author(s)
      Watari K, Shibata T, Kawahara A, Sata K, Nabeshima H, Shinoda A, Abe H, Azuma K, Murakami Y, Izumi, H, Takahashi T, Kage M, Kuwano M, Ono M.
    • Journal Title

      PLoS ONE

      Volume: 9 Issue: 6 Pages: e99568-e99568

    • DOI

      10.1371/journal.pone.0099568

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22134005, KAKENHI-PROJECT-23300350, KAKENHI-PROJECT-25830083, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-25250017
  • [Journal Article] Rheb-syntenin interaction regulates dendritic spine formation in rodent models of tuberous sclerosis.2014

    • Author(s)
      285. Sugiura H., Yasuda S., Katsurabayashi S., Oguri K., Tanaka H., Takasaki K., Iwasaki K., Kobayashi T., Hino O. and Yamagata K.
    • Journal Title

      PNAS

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670196
  • [Journal Article] ERC/mesothelin is expressed in human gastric cancer tissues and cell lines.2014

    • Author(s)
      Ito T, Kajino K, Abe M, Hino O et al.
    • Journal Title

      Oncology reports

      Volume: 31 Issue: 1 Pages: 27-33

    • DOI

      10.3892/or.2013.2803

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] RASEF is a novel diagnostic biomarker and a therapeutic target for lung cancer.2013

    • Author(s)
      Oshita H, Nishino R, Takano A, Fujitomo T, Aragaki M, Kato T, Akiyama H, Tsuchiya E, Kohno N, Nakamura Y, Daigo Y.
    • Journal Title

      Mol Cancer Res

      Volume: 11 Issue: 8 Pages: 937-951

    • DOI

      10.1158/1541-7786.mcr-12-0685-t

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23650624, KAKENHI-PROJECT-23659433, KAKENHI-PROJECT-24390145, KAKENHI-PROJECT-25253057, KAKENHI-PROJECT-221S0001
  • [Journal Article] Tuberin activates and controls the distribution of Rac1 viaassociation with p62 and ubiquitinthrough the mTORC1 signaling pathway2013

    • Author(s)
      Okura H, Kobayashi T, Zhang D, Hino O, et al
    • Journal Title

      Int J Oncol

      Volume: 2 Pages: 5-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500389
  • [Journal Article] Up-regulation of dbpA mRNA in hepatocellular carcinoma associated with metabolic syndrome2013

    • Author(s)
      Obulhasim G., Yasen M., Kajino K., Mogushi K., Tanaka S., Mizushima H., Tanaka H., Arii S. and Hino O
    • Journal Title

      Hepatol. Int

      Volume: 7 Pages: 215-225

    • Data Source
      KAKENHI-PROJECT-23659206
  • [Journal Article] Improved PCR amplification for molecular analysis using DNA from long-term preserved formalin-fixed, paraffin-embedded lung cancer tissue specimens.2013

    • Author(s)
      Taga M, Eguchi H, Shinohara T et al.
    • Journal Title

      Int J Clin Exp Pathol

      Volume: 6 Pages: 76-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] Folliculin regulates cyclin D1 expression through cis-acting elements in the 3' untranslated region of cyclin D1 mRNA2013

    • Author(s)
      Kawai A, Kobayashi T, Hino O
    • Journal Title

      Int J Oncol

      Volume: 42(5) Issue: 5 Pages: 1597-604

    • DOI

      10.3892/ijo.2013.1862

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500389
  • [Journal Article] Src plays a key role in ADAM28 expression in v-src-transformed epithelial cells and human carcinoma cells.2013

    • Author(s)
      Abe H., Mochizuki S., Ohara K., Ueno M., Ohiai H., Kitagawa Y., Hino O., Sato H. and Okada Y.
    • Journal Title

      The American Journal of Pathology

      Volume: 183 Pages: 1667-1678

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670196
  • [Journal Article] The N-ERC index is a novel monitoring and prognostic marker for advanced malignant pleural mesothelioma.2013

    • Author(s)
      Mori T, Tajima K, Hirama M, Hino O et al.
    • Journal Title

      Journal of thoracic disease

      Volume: 5 Pages: 145-148

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] “Intraperitoreal Administration of Tangled Multiwall Carbon Nanotubes of 15 nm in Diameter Does Not Induce Mesothelial Carcinogenesis in Rats”2013

    • Author(s)
      H.Nagai
    • Journal Title

      Pathology International

      Volume: 63 Issue: 9 Pages: 457-462

    • DOI

      10.1111/pin.12093

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22225001, KAKENHI-PLANNED-24108008, KAKENHI-PROJECT-24390094, KAKENHI-PROJECT-25860292, KAKENHI-PROJECT-221S0001
  • [Journal Article] Aberrant methylation of microRNA-34b/c is a predictive marker of metachronous gastric cancer risk.2013

    • Author(s)
      Suzuki R, Yamamoto E, Nojima M, Maruyama R, Yamano HO, Yoshikawa K, Kimura T, Harada T, Ashida M, Niinuma T, Sato A, Nosho K, Yamamoto H, Kai M, Sugai T, Imai K, Suzuki H, Shinomura Y.
    • Journal Title

      J Gastroenterol

      Volume: [Epub ahead of print]

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] TSC1 controls distribution of actin fibers through its effect on function of Rho family of small GTPases and regulates cell migration and polarity2013

    • Author(s)
      Ohsawa M, Kobayashi T, Hino O, et al
    • Journal Title

      PLoS One

      Volume: 8(1) Issue: 1 Pages: e54503-e54503

    • DOI

      10.1371/journal.pone.0054503

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500389, KAKENHI-PROJECT-24659490, KAKENHI-PROJECT-25670196
  • [Journal Article] TSC1 controls distribution of actin fibers through its effect on function of Rho family of small GTPases and regulates cell migration and polarity2013

    • Author(s)
      Osawa M., Kobayashi T., Okura H., Igarashi T., MizuguchiM. and Hino O
    • Journal Title

      Plos One

      Volume: 8 Pages: 1-13

    • Data Source
      KAKENHI-PROJECT-23659206
  • [Journal Article] Tuberin activates and controls the distribution of Rac1 via association with p62 and ubiquitin through the mTORC1 signaling pathway.2013

    • Author(s)
      Okura, H., Kobayashi, T., Koike, M., Ohsawa, M., Zhang, D., Arai, H., Uchiyama, Y., *Hino O
    • Journal Title

      Int J Oncol

      Volume: 43 Issue: 2 Pages: 447-456

    • DOI

      10.3892/ijo.2013.1984

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23111004, KAKENHI-PROJECT-23390041, KAKENHI-PROJECT-23659206, KAKENHI-PROJECT-25460276, KAKENHI-PROJECT-25670099, KAKENHI-PROJECT-25670196
  • [Journal Article] Mesothelin expression is a prognostic factor in cholangiocellular carcinoma.2013

    • Author(s)
      Nomura R, Fujii H, Abe M, Hino O et al.
    • Journal Title

      International surgery

      Volume: 98 Issue: 2 Pages: 164-169

    • DOI

      10.9738/intsurg-d-13-00001.1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] NP-1250, an ABCG2 inhibitor, induces apoptotic cell death in breast carcinoma MCF7/mitoxantrone-resistant cells via a caspase-independent pathway2013

    • Author(s)
      Ito M., Kajino K., Abe M., Fujimura T., Mineki R., Ikegami T., Ishikawa T. and Hino O
    • Journal Title

      Oncology Reports

      Volume: 29 Pages: 1492-1500

    • Data Source
      KAKENHI-PROJECT-23659206
  • [Journal Article] Detailed analysis of Japanese population substructure with a focus on the Southwest Islands of Japan2012

    • Author(s)
      Nishiyama, T., Kishino, H., Suzuki, S., Ando, R., Niimura, H., Uemura, H., Horita, M., Ohnaka, K., Kuriyama, N., Mastuo, K., Guang, Y., Wakai, K., Hamajima, N., and Tanaka, H
    • Journal Title

      PLoS ONE

      Volume: 7(4) Issue: 4 Pages: e35000-e35000

    • DOI

      10.1371/journal.pone.0035000

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22300095, KAKENHI-PROJECT-23590806, KAKENHI-PROJECT-23790668, KAKENHI-PROJECT-221S0001
  • [Journal Article] DNA binding protein A exression and methylation status in hepatocellular carcinoma and the adjacent tissue2012

    • Author(s)
      Yasen M., Obulhasim G., Kajino K., Mogushi K., Mizushima H., Tanaka S., Tanaka H., Hino O. and Arii S
    • Journal Title

      Int. J. Oncology

      Volume: 40 Pages: 789-797

    • Data Source
      KAKENHI-PROJECT-23659206
  • [Journal Article] The utility of serum N-ERC/mesothelin as biomarker of ovarian carcinoma2012

    • Author(s)
      Saeki H., Hashizume A., Izumi H., Suzuki F., Ishi K., Nojima M., Maeda M. and Hino O.
    • Journal Title

      Oncology Letters

      Volume: 4 Pages: 637-641

    • Data Source
      KAKENHI-PROJECT-22240093
  • [Journal Article] Diaminopyridine-Based Potent and Selective Mps1 Kinase Inhibitors Binding to an Unusual Flipped-Peptide Conformation.2012

    • Author(s)
      Kusakabe K, Ide N, Daigo Y, Itoh T, Higashino K, Okano Y, Tadano G, Tachibana Y, Sato Y, Inoue M, Wada T, Iguchi M, Kanazawa T, Ishioka Y, Dohi K, Tagashira S, Kido Y, Sakamoto S, et al.
    • Journal Title

      ACS Med Chem Lett

      Volume: 3 Pages: 560-564

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] Model of translational cancer research in multiple myeloma.2012

    • Author(s)
      Yasui H, Ishida T, Maruyama R, Nojima M, Ikeda H, Suzuki H, Hayashi T, Shinomura Y, Imai K.
    • Journal Title

      Cancer Sci

      Volume: 103 Pages: 1207-1212

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] Preventing of alveolar destruction and airspace enlargement in a mouse Model of pulmonary lymphangioleiomyomatosis (LAM)2012

    • Author(s)
      Goncharova E.A., Goncharov D.A., Fehrenbach M., Khavin I., Ducka B., Hino O., Colby T.V., Merrilees M.J., Haczku A., Albelada S.M. and Krymskaya V.
    • Journal Title

      Science Translational Medicine

      Volume: 4 Pages: 1-10

    • Data Source
      KAKENHI-PROJECT-23659206
  • [Journal Article] Iron overload signature in chrysotile-induced malignant mesothelioma.2012

    • Author(s)
      Jiang L, Akatsuka S, Nagai H, Chew SH, Ohara H, Okazaki Y, Yamashita Y, Yoshikawa Y, Yasui H, Ikuta K, Sasaki K, Kohgo Y, Hirano S, Shinohara Y, Kohyama N, Takahashi T, Toyokuni S.
    • Journal Title

      J Pathol

      Volume: 228 Issue: 3 Pages: 366-77

    • DOI

      10.1002/path.4075

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590394, KAKENHI-PROJECT-23591363, KAKENHI-PROJECT-24390094, KAKENHI-PROJECT-24591377, KAKENHI-PROJECT-221S0001
  • [Journal Article] Rapamycin reverses impaired social interaction in mouse models of tuberous sclerosis complex2012

    • Author(s)
      Sato A., Kasai S., Kobayashi T., Takamatsu Y., Hino O., Ikeda K. and Mizuguchi M
    • Journal Title

      Nature Communications

      Volume: 2295 Pages: 1-9

    • Data Source
      KAKENHI-PROJECT-23659206
  • [Journal Article] Prostate cancer chemoprevention study : an investigative randomized control study using purified isoflavones in men with rising prostatespecific antigen2012

    • Author(s)
      Miyanaga N, et al
    • Journal Title

      Cancer science

      Volume: 103 Issue: 1 Pages: 125-130

    • DOI

      10.1111/j.1349-7006.2011.02120.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] LRR4 and UPK3B are markers of primary mesothelial cells2011

    • Author(s)
      Kanamori-Katayama M., Kaiho A., Ishizu Y., Okamura-Oho Y., Hino O., Abe M., Kishimoto T., Sekihara H., Nakamura Y., Suzuki H., Forrest A.R.R. and Hayashizaki Y.
    • Journal Title

      PLoS One

      Volume: 6

    • Data Source
      KAKENHI-PROJECT-22240093
  • [Journal Article] HCV core protein promotes heparin binding EGF-like growth factor expression and activates Akt2011

    • Author(s)
      Nakamura H., Aoki H., Hino O. and Moriyama M
    • Journal Title

      Hepatology Research

      Volume: 4 Pages: 455-462

    • NAID

      10031144111

    • Data Source
      KAKENHI-PROJECT-23659206
  • [Journal Article] Feasibility of large-scale screening using N-ERC/mesothelin levels in the blood for the early diagnosis of malignant mesothelioma2011

    • Author(s)
      Imashimizu K., Shiomi K., Maeda M., Aoki N., Igarashi K., Suzuki F., Koizumi M., Suzuki K. and Hino O.
    • Journal Title

      Experimental and Therapeutic Medicine

      Volume: 2 Pages: 409-411

    • Data Source
      KAKENHI-PROJECT-22240093
  • [Journal Article] Impact of renal failure on the tumor markers of mesothelioma, N-ERC/mesothelin and Osteopontin2011

    • Author(s)
      Shiomi K., Shiomi S., Ishinaga Y., Sakuraba M., Hagiwara Y., Miyashita K., Maeda M., Suzuki K., Takahashi K. and Hino O.
    • Journal Title

      Anticancer Research

      Volume: 31 Pages: 1427-1430

    • Data Source
      KAKENHI-PROJECT-22240093
  • [Journal Article] Deficiency of the Erc/mesothelingene ameliorates renal carcinogenesis in Tsc2 knockout mice2011

    • Author(s)
      Zhang D., Kobayashi T., Kojima T., Kanenishi K., Hagiwara Y., Abe M., Okura H., Hamano Y., Sun G., Maeda M., Jishage K., Noda T. and Hino O.
    • Journal Title

      Cancer Science

      Volume: 102 Pages: 720-727

    • Data Source
      KAKENHI-PROJECT-22240093
  • [Journal Article] Autophagy-deficient mice develop multiple liver tumors2011

    • Author(s)
      Takamura A., Komatsu M., Hara T., Sakamoto A., Kishi C., Waguri S., Eishi Y., Hino O., Tanaka K. and Mizushima N
    • Journal Title

      Gene & Development

      Volume: 25 Pages: 795-800

    • Data Source
      KAKENHI-PROJECT-23659206
  • [Journal Article] Identitication of Epstein-Barr Virus-Induced Gene 3 as a Novel Serum and Tissue Biomarker and a Therapeutic Target for Lung Cancer2011

    • Author(s)
      Nishino R, et al
    • Journal Title

      Clin Cancer Res

      Volume: 17 Issue: 19 Pages: 6272-6286

    • DOI

      10.1158/1078-0432.ccr-11-0060

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] Deficiency of the Erc/mesothelin gene ameliorates renal carcinogenesis in Tsc2 knockout mice2011

    • Author(s)
      Zhang D, Kobayashi T, Hino O, et al
    • Journal Title

      Cancer Sci

      Volume: 102(4) Issue: 4 Pages: 720-7

    • DOI

      10.1111/j.1349-7006.2011.01846.x

    • NAID

      10029291977

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500389, KAKENHI-PROJECT-23510244
  • [Journal Article] Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells2011

    • Author(s)
      Inami Y., Waguri S., Sakamoto A., Kouno T., Nakada K., Hino O., Watanabe S., Andoh J., Iwadate M., Yamamoto M., Lee M-S., Tanaka K. and Komatsu M
    • Journal Title

      J. Cell Biology

      Volume: 193 Pages: 275-284

    • Data Source
      KAKENHI-PROJECT-23659206
  • [Journal Article] Antitumor activity of anti-C-ERC/mesothelin monoclonal antibody in vivo2010

    • Author(s)
      Inami K., Abe M., Takeda K., Hagiwara Y., Maeda M., Segawa T., Suyama M., Watanabe S. and Hino O.
    • Journal Title

      Cancer Sci

      Volume: 101 Pages: 969-974

    • NAID

      10026591120

    • Data Source
      KAKENHI-PROJECT-22240093
  • [Journal Article] Serum level of expressed in renal carcinoma (ERC)/mesothelin in rats with mesothelial proliferative lesions induced by multi-wall carbon nanotube (MWCNT)2010

    • Author(s)
      Sakamoto Y., Nakae D., Hagiwara Y., Satoh K., Ohashi N., Fukamachi K., Tsuda H., Hirose A., Nishimura T., Hino O. and Ogata A.
    • Journal Title

      The Jounal of Toxicological Sciences

      Volume: 35 Pages: 265-270

    • NAID

      10026193564

    • Data Source
      KAKENHI-PROJECT-22240093
  • [Journal Article] Antitumor activity of anti-C-ERC/mesothelin monoclonal antibody in vivo2010

    • Author(s)
      Inami K, Abe M, Hino O, et al
    • Journal Title

      Cancer Sci

      Volume: 101(4) Issue: 4 Pages: 969-74

    • DOI

      10.1111/j.1349-7006.2009.01463.x

    • NAID

      10026591120

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500389
  • [Journal Article] Serine 62 is phosphorylation site in folliculin, the Birt-Hogg-Dube gene product.2010

    • Author(s)
      Wang L., Kobayashi T., Piao X., Shiono M., Takagi Y., Mineki R., Taka H., Zhang D., Abe M., Son G., Hagiwara Y., Okimoto K., Matsumoto I., Kouchi M., Hino O.
    • Journal Title

      FEBS Letters 584

      Pages: 39-43

    • Data Source
      KAKENHI-PROJECT-17013076
  • [Journal Article] Age dependence of radiation-induced renal cell carcinomas in an Eker rat model.2010

    • Author(s)
      Kokubo T., Kakinuma S., Kobayashi T., Watanabe F., Iritani R., Tateno K., Nishimura M., Nishikawa T., Hino O., Shimada Y.
    • Journal Title

      Cancer Sci. 101

      Pages: 616-623

    • NAID

      10026589138

    • Data Source
      KAKENHI-PROJECT-17013076
  • [Journal Article] Mesothelin gene expression and promoter methylation/hypomethylation in gynecological tumors2010

    • Author(s)
      Obulhasim G., Fujii H., Matsumoto T., Yasen M., Abe M., Matsuoka S., Ohtsuji N. and Hino O.
    • Journal Title

      Eur. J. Gynaec. Oncol.

      Volume: 31 Pages: 63-71

    • Data Source
      KAKENHI-PROJECT-22240093
  • [Journal Article] Antitumor activity of anti-C-ERC/mesothelin monoclonal antibody in vivo.2010

    • Author(s)
      Inami K., Abe M., Takeda K., Hagiwara Y., Maeda M., Segawa T., Suyama M., Watanabe S., Hino O.
    • Journal Title

      Cancer Sci. 101

      Pages: 969-974

    • NAID

      10026591120

    • Data Source
      KAKENHI-PROJECT-17013076
  • [Journal Article] Knockdown of COPA, identified by loss-of-functiuon screen, induces apoptosis and suppresses tumor growth in mesothelioma mouse mode2010

    • Author(s)
      Sudo H., Tuji A., Sugyo A., Kohda M., Sogawa C., Yoshida C., Harada Y., Hino O. and Saga T.
    • Journal Title

      Genomics

      Volume: 95 Pages: 210-216

    • Data Source
      KAKENHI-PROJECT-22240093
  • [Journal Article] Serine 62 is a phosphorylation site in folliculin, the Birt-Hogg-Dubegene product2010

    • Author(s)
      Wang L, Kobayashi T, Zhang D, Hino O, et al
    • Journal Title

      FEBS Lett

      Volume: 584(1) Issue: 1 Pages: 39-43

    • DOI

      10.1016/j.febslet.2009.11.033

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500389
  • [Journal Article] Phosphorylated hamartin-Hsp70 complex regulates apoptosis via mitochondrial localization2010

    • Author(s)
      Inoue H, Hino O, Kobayashi T, et al
    • Journal Title

      iochem Biophys Res Commun

      Volume: 391(1) Issue: 1 Pages: 1148-53

    • DOI

      10.1016/j.bbrc.2009.12.054

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500389
  • [Journal Article] Phosphorylated hamartin-Hsp70 complex regulates apoptosis via mitochondrial localization.2010

    • Author(s)
      Inoue H., Uyama T., Suzuki T., Kazami M., Hino O., Kobayashi T., Kobayashi K., Tadokoro T.
    • Journal Title

      Biochem. Biophys. Res. Commun. 391

      Pages: 1148-1153

    • Data Source
      KAKENHI-PROJECT-17013076
  • [Journal Article] Suppression of cell death by the secretory form of N-terminal ERC/mesothelin2010

    • Author(s)
      Wang T., Kajino K., Abe M., Tan K., Maruo M., Sun G., Hagiwara Y., Maeda M. and Hino O.
    • Journal Title

      Int. J. Molecular Med

      Volume: 26 Pages: 185-191

    • Data Source
      KAKENHI-PROJECT-22240093
  • [Journal Article] Mesothelin (MSLN) promoter is hypomethylated in malignant mesothelioma, but its expression is not associated with methylation status of the promoter2010

    • Author(s)
      Tan K., Kajino K., Momose S., Masaoka A., Sasahara K., Shiomi K., Izumi H., Abe M., Ohtsuji N., Wang T., Hino O. and Fujii H.
    • Journal Title

      Human Pathol

      Volume: 41 Pages: 1330-1338

    • Data Source
      KAKENHI-PROJECT-22240093
  • [Journal Article] Frequent expression of Niban in head and neck squamous cell carcinoma and squamous dysplasia.2010

    • Author(s)
      Ito S., Fujii H., Matsumoto T., Abe M., Ikeda K., Hino O.
    • Journal Title

      Head Neck 32

      Pages: 96-103

    • Data Source
      KAKENHI-PROJECT-17013076
  • [Journal Article] Age dependence of radiation-induced renal cell carcinomas in an Eker rat model2010

    • Author(s)
      T. Kokubo, S. Kakinuma, M. Nishimura, Y. Shimada, et. Al
    • Journal Title

      Cancer Science

      Volume: 101(3) Issue: 3 Pages: 616-623

    • DOI

      10.1111/j.1349-7006.2009.01456.x

    • NAID

      10026589138

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21610029, KAKENHI-PROJECT-22500389
  • [Journal Article] Suppression of cell death by the secretory form of N-terminal ERC/mesothelin2010

    • Author(s)
      Wang T, Kajino K, Hino O, et al
    • Journal Title

      Int J Mol Med

      Volume: 26(2) Pages: 185-91

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/20596597

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500389
  • [Journal Article] Development of positron emission tomography imaging by 64Cu-labeled Fab for detecting ERC/mesothelin in mesothelioma mouse model2010

    • Author(s)
      Yoshida C., Sogawa C., Tsuji A., Sudo H., Sugyo A., Uehara T., Hino O., Yoshii Y., Fujibayashi Y., Fukumura T., Koizumi M., Arano Y. and Saga T.
    • Journal Title

      Nuclear Medicine Communications

      Volume: 31 Pages: 380-388

    • Data Source
      KAKENHI-PROJECT-22240093
  • [Journal Article] Mesothelin (MSLN) promoter is hypomethylated in malignant mesothelioma, but its expression is not associated with methylation status of the promoter2010

    • Author(s)
      Tan K, Hino O, Fujii H, et al
    • Journal Title

      Hum Pathol

      Volume: 41(9) Issue: 9 Pages: 1330-8

    • DOI

      10.1016/j.humpath.2010.03.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500389
  • [Journal Article] Regulation of folliculin (the BHD gene product) phosphorylation by Tsc2-mTOR pathway.2009

    • Author(s)
      Piao X., Kobayashi T., Wang L., Shiono M., Takagi Y., Sun G., Abe M., Hagiwara Y., Zhang D., Okimoto K., Kouchi M., Matsumoto I., Hino O.
    • Journal Title

      Biochem. Biophys. Res. Commun. 389

      Pages: 16-21

    • Data Source
      KAKENHI-PROJECT-17013076
  • [Journal Article] Establishment of novel monoclonal antibody to human ERC/mesothelin useful for study and diagnosis of ERC/mesothelin-expressing cancers.2009

    • Author(s)
      Ishikawa K., Segawa T., Hagiwara Y., Maeda M., Abe M., Hino O.
    • Journal Title

      Pathol. Int. 59

      Pages: 161-166

    • Data Source
      KAKENHI-PROJECT-17013076
  • [Journal Article] An animal model of precilinical diagnosis of pancreatic ductal carcinomas.2009

    • Author(s)
      Fukamachi K., Tanaka H., Hagiwara Y., Ohara H., Joh T., Iigo M., Alexander D.B., Xu J., Long N., Takigahira M., Yonagihara K., Hino O., Saito I.
    • Journal Title

      Biochem. Biophys. Res. Commun. 390

      Pages: 636-641

    • Data Source
      KAKENHI-PROJECT-17013076
  • [Journal Article] Establishment and chracterization of renal carcinoma cell lines from a Bhd gene mutant (Nihon) rat.2009

    • Author(s)
      Matsumoto I., Kouchi M., Okimoto K., Kijima K., Ueda T., Hirayama Y., Inoue T., Hino O.
    • Journal Title

      Tumor Biology 30

      Pages: 249-256

    • Data Source
      KAKENHI-PROJECT-17013076
  • [Journal Article] Biphasic response of pancreatic β cell mass to ablation of TSC2 mice.2008

    • Author(s)
      Shigeyama Y., Kobayashi T., Kido Y., Hashimoto N., Asahara S., Matsuda T., Takeda A., Inoue T., Shibutani Y., Koyanagi M., Uchida T., Inoue M., Hino O., Kasuga M., Noda T.
    • Journal Title

      Mol. Cell. Biology 28

      Pages: 2971-2979

    • Data Source
      KAKENHI-PROJECT-17013076
  • [Journal Article] Mesomark kit detects C-ERC/mesothelin, but not SMRP with C-terminus.2008

    • Author(s)
      Segawa T., Hagiwara Y., Ishikawa K., Aoki N., Maeda M., Shiomi K., Hino O.
    • Journal Title

      BBRC 369

      Pages: 915-918

    • Data Source
      KAKENHI-PROJECT-17013076
  • [Journal Article] siRNA-mediated Erc gene silencing suppresses tumor growth in Tsc2 mutant renal carcinoma model.2008

    • Author(s)
      Imamura O., Okada H., Takashima Y., Zhang D., Kobayashi T., Hino O.
    • Journal Title

      Cancer Letters 268

      Pages: 278-285

    • Data Source
      KAKENHI-PROJECT-17013076
  • [Journal Article] Secretion of N-ERC/mesothelin and expression of C-ERC/mesothelin in human pancreatic ductal carcinoma.2008

    • Author(s)
      Inami K., Kajino K., Abe M., Hgiwara Y., Maeda M., Suyama M., Watanabe S., Hino O.
    • Journal Title

      Oncology Reports 20

      Pages: 1375-1380

    • Data Source
      KAKENHI-PROJECT-17013076
  • [Journal Article] The G1556S-type tuberin variant suppresses tumor formation in tuberous sclerosis 2 mutant (Eker) rats despite its deficiency in mTOR inhibition.2008

    • Author(s)
      Shiono M., Kobayashi T., Takahashi R., Sun G., Abe M., Zhang D., Wang L., Piao X., Takagi Y., Mineki R., Taka H., Tada N., Sonobe S., Momose S., Ueda M., Hino O.
    • Journal Title

      Oncogene 27

      Pages: 6690-6697

    • Data Source
      KAKENHI-PROJECT-17013076
  • [Journal Article] Tuberous sclerosis complex 2 loss-of-function mutation regulates reactive oxygen species production through Rac1 activation2008

    • Author(s)
      Suzuki T, Das SK, Inoue H, Kazami M, Hino O, Kobayashi T, Yeung RS, Kobayashi KI, Tadokoro T, Yamamoto Y.
    • Journal Title

      Biochem Biophys Res Commun 368

      Pages: 132-137

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500222
  • [Journal Article] Tuberous sclerosis complex 2 loss-of-function mutation regulates reactive oxygen species production through Racl activation.2008

    • Author(s)
      Suzuki T., Das S.K., Inoue H., Kazami M., Hino O., Kobayashi T., Yeung R.S., Kobayashi K., Tadokoro T., Yamamoto Y.
    • Journal Title

      Biochem. Biophys. Res. Commun 368

      Pages: 132-137

    • Data Source
      KAKENHI-PROJECT-17013076
  • [Journal Article] Establishment of a Novel Specific ELISA system for rat N- and C-ERC/Mesothelin. -Rat ERC/Mesothelin in the body fluids of mice bearing mesothelioma-.2008

    • Author(s)
      Hagiwara Y., Hamada Y., Kuwahara M., Maeda M., Segawa T., Ishikawa K., Hino O.
    • Journal Title

      Cancer Sci. 99

      Pages: 666-670

    • NAID

      10024004555

    • Data Source
      KAKENHI-PROJECT-17013076
  • [Journal Article] Sensitive and specific new enzyme-linked immunosorbent assay for N-ERC/mesothelin increases its potential as a useful serum tumor marker for mesothelioma.2008

    • Author(s)
      Shiomi K., Hagiwara Y., Sonoue K., Segawa T., Miyashita K., Maeda M., Izumi H., Masuda K., Hirabayashi M., Moroboshi T., Yoshiyama T., Ishida A., Natori Y., Inoue A., Kobayashi M., Sakao Y., Miyamoto H., Takahashi K., Hino O.
    • Journal Title

      Clinical Cancer Res. 14

      Pages: 1431-1437

    • Data Source
      KAKENHI-PROJECT-17013076
  • [Journal Article] ERC/mesothelin as a marker for chemotherapeutic response in patients with mesothelioma.2008

    • Author(s)
      Tajima K., Hirama M., Shiomi K, Ishiwata T., Yoshioka M., Iwase A., Iwakami S., Yamazaki M., Toba M., Tobino K., Sugano K., Ichikawa M., Hagiwara Y., Takahashi K., Hino O.
    • Journal Title

      Anticancer Research 28

      Pages: 3933-3936

    • Data Source
      KAKENHI-PROJECT-17013076
  • [Journal Article] Interaction of folliculin (Birt-Hogg-Dube gene product) with a novel Fnipl-like (FnipL/Fnip2) protein.2008

    • Author(s)
      Takagi Y., Kobayashi, T., Shiono M., Wang L., Piao X., Sun G., Zhang D., Abe M., Hagiwara Y., Takahashi K., Hino O.
    • Journal Title

      Oncogene 27

      Pages: 5339-5347

    • Data Source
      KAKENHI-PROJECT-17013076
  • [Journal Article] Diagnostic tumor marker of asbestos-related messoth.2008

    • Author(s)
      Hino O., Maeda, M.
    • Journal Title

      Environmental Health and Preventive Medicine 13

      Pages: 71-74

    • Data Source
      KAKENHI-PROJECT-17013076
  • [Journal Article] The endoplasmic reticulum stress-inducible protein Niban regulates eIF2 α and S6K1/4E-BP1 phosphorylation.2007

    • Author(s)
      Sun G.D., Kobayashi T., Abe M., Tada N., Adachi H., Shiota A., Totsuka Y., Hino O.
    • Journal Title

      Biochem. Biophys. Res. Commun 360

      Pages: 181-187

    • Data Source
      KAKENHI-PROJECT-17013076
  • [Journal Article] GADD34 inhibits mammalian target of rapamycin signaling via tubero us sclerosis complex and controls cell survival under bioenergetic stress.2007

    • Author(s)
      Watanabe R, Tambe Y, Inoue H, Isono T, Haneda M, Isobe K, Kobayashi T, Hino O, et al.
    • Journal Title

      Int J Mol Med. 19・3

      Pages: 475-83

    • Data Source
      KAKENHI-PROJECT-18500330
  • [Journal Article] Establishment of the enzyme-linked immunosorbent assay system to detect the amino terminal secretory form of rat Erc/Mesothelin2007

    • Author(s)
      Nakaishi M, Kajino K, Ikesue M, Hagiwara Y, Kuwahara M, Mitani H, Horikoshi-Sakuraba Y, Segawa T, Kon S, Maeda M, Wang T, Abe M, Yokoyama M, Hino O.
    • Journal Title

      Cancer Sci 98

      Pages: 659-664

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500222
  • [Journal Article] Establishment of the enzyme-linked immunosorbent assay system to detect the amino terminal secretory form of rat Erc/Mesothelin2007

    • Author(s)
      Nakaishi, M., Kajino, K., Ikesue, M., Hagiwara, Y., Kuwahara, M., Mitani, H., Horikoshi-Sakuraba, Y., Segawa, T., Kon, S., Maeda, M., Wang, T., Abe, M., Yokoyama, M., Hino, O
    • Journal Title

      Cancer Sci 98

      Pages: 659-64

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590748
  • [Journal Article] Suppression of viral replication by stress-inducible GADD34 protein via the mammalian serine/threonine protein kinase mTOR pathway.2007

    • Author(s)
      Minami K., Tambe Y., Watanabe R., Isono T., Haneda M., Isobe K., Kobayashi T., Hino O., Okabe H., Chano T., Inoue H.
    • Journal Title

      J. Virology 81

      Pages: 11106-11115

    • Data Source
      KAKENHI-PROJECT-17013076
  • [Journal Article] A diagnostic biomarker of Asbestos-related mesothelioma-Example of translational research-2007

    • Author(s)
      Hino, O., et. al.
    • Journal Title

      Cancer Science 98

      Pages: 1147-1157

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013076
  • [Journal Article] GADD34 inhibits mammalian target of rapamycin signaling via tuberous sclerosis complex and controls cell survival under bioenergetic stress2007

    • Author(s)
      Watanabe R, Tambe Y, Inoue H, Isono T, Haneda M, Isobe K, Kobayashi T, Hino O, Okabe H, Chano T.
    • Journal Title

      Int J Mol Med 19

      Pages: 475-483

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500222
  • [Journal Article] N-terminal hamartin-binding and C-terminal GAP domain of tuberin can separate in vivo2007

    • Author(s)
      Momose S, Kobayashi T, Tada N, Itoyama S, Hino O.
    • Journal Title

      Biochem Biophys Res Commun 356

      Pages: 693-698

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500222
  • [Journal Article] Establishment of the ELISA system to detect the amino terminal secretory form of rat Erc/ Mesothelin.2007

    • Author(s)
      Nakaishi M., Kajino K., Ikesue M., Hagiwara Y., Kuwahara M., Mitani H., Horikoshi Y., Segawa T., Kon S., Maeda M., Baiyin T., Abe M., Yokoyama M., Hino O.
    • Journal Title

      Cancer Sci. 98

      Pages: 659-664

    • Data Source
      KAKENHI-PROJECT-17013076
  • [Journal Article] N-terminal hamartin-binding and C-terminal GAP domain of tuberin can separate in vivo N-terminal hamartin-binding and C-termin.2007

    • Author(s)
      Momose S., Kobayashi T., Tada N., Itoyama S., Hino O.
    • Journal Title

      Biochem. Biophys. Res. Commun 356

      Pages: 693-698

    • Data Source
      KAKENHI-PROJECT-17013076
  • [Journal Article] Blood Tests for Asbestos-Related Mesothelioma.2007

    • Author(s)
      Maeda M, Hino O
    • Journal Title

      Oncology 71・1-2

      Pages: 26-31

    • Data Source
      KAKENHI-PROJECT-18500330
  • [Journal Article] GADD34 inhibits mammalian target of repamycin signaling via tuberous sclerosis complex and controls cell surbival under bioenergetic stress.2007

    • Author(s)
      Watanabe R., Tambe Y., Inoue H., Isono T., Haneda M., Isobe K., Kobayashi T., Hino O., Okabe H., Chano T.
    • Journal Title

      Int. J. Molecular Medicine 19

      Pages: 475-483

    • Data Source
      KAKENHI-PROJECT-17013076
  • [Journal Article] Birt-Hogg-Dube (BHD) gene mutations in human gastric cancer with high hrequency microsatellite instability.2007

    • Author(s)
      Jiang W., Fujii H., Matsumoto T., Ohtsuji N., Tsurumaru M., Hino O.
    • Journal Title

      Cancer Letter 248

      Pages: 103-111

    • Data Source
      KAKENHI-PROJECT-17013076
  • [Journal Article] A diagnostic biomarker of Asbestos-related mesothelioma-Example of translational research-.2007

    • Author(s)
      Hino O., Shiomi K., Maeda M.
    • Journal Title

      Cancer Sci. 98

      Pages: 1147-1157

    • Data Source
      KAKENHI-PROJECT-17013076
  • [Journal Article] [対がん戦略」がんの本質にせまる 疾患モデル2006

    • Author(s)
      樋野興夫
    • Journal Title

      綜合臨床 55

      Pages: 419-424

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17500222
  • [Journal Article] Novel ELISA system for detection on N-ERC/mesothelin in the sera of mesothelioma patients.2006

    • Author(s)
      Shiomi K, Miyamoto H, Segawa T, Higiwara Y, Hino O, et al.
    • Journal Title

      Cancer Sci. 97・9

      Pages: 928-932

    • NAID

      10018767738

    • Data Source
      KAKENHI-PROJECT-18500330
  • [Journal Article] Molecular tumor markers for asbestos-related mesothelioma : serum diagnostic markers2006

    • Author(s)
      Maeda M, Hino O.
    • Journal Title

      Pathol Int 56

      Pages: 649-654

    • NAID

      10018400089

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500222
  • [Journal Article] Transgenic rescue from embryonic lethality and renal carcinogenesis in the Nihon rat model by introduction of a wild-type Bhd gene.2006

    • Author(s)
      Togashi Y, Kobayashi T, Momose S, Ueda M, Okimoto K, Hino O
    • Journal Title

      Oncogene 25

      Pages: 2885-2889

    • Data Source
      KAKENHI-PROJECT-17013076
  • [Journal Article] Novel ELISA system for detection of "N-ERC/mesothelin" in the sera of mesothelioma patients.2006

    • Author(s)
      Shiomi K., Miyamoto H., Segawa T., Hagiwara Y., Ota A., Maeda M., Takahashi K., Masuda K., Sakao Y., Hino O.
    • Journal Title

      Cancer Sci 97

      Pages: 928-932

    • NAID

      10018767738

    • Data Source
      KAKENHI-PROJECT-17013076
  • [Journal Article] Genetic and environmental factors in hereditary predisposition to tumors: a conceptual overview.2006

    • Author(s)
      Hino O, et. al.
    • Journal Title

      EXS 96

      Pages: 269-292

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17500222
  • [Journal Article] Disease models(in Japanese)2006

    • Author(s)
      Hino O.
    • Journal Title

      Sogo Rinsho 55

      Pages: 419-424

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500222
  • [Journal Article] A novel tumor marker, Niban, is expressed in subsets of thyroid tumors and Hashimoto's thyroiditis2006

    • Author(s)
      Matsumoto, F., Fujii, H., Abe, M., Kajino, K., Kobayashi, T., Matsumoto, T., Ikeda, K., Hino, O
    • Journal Title

      Hum Pathol 37

      Pages: 1592-600

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590748
  • [Journal Article] Tuberous sclerosis(in Japanese)2006

    • Author(s)
      Hino O, Kobayashi T.
    • Journal Title

      Genome Igaku 6

      Pages: 89-94

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500222
  • [Journal Article] A novel tumor marker, Niban, is expressed in subsets of thyroid tumors and Hashimoto's thyroiditis.2006

    • Author(s)
      Matsumoto F., Fujii H., Abe M., Kajino K., Kobayashi T., Matsumoto T., Ikeda K., Hino O.
    • Journal Title

      Human Pathology 37

      Pages: 1592-1600

    • Data Source
      KAKENHI-PROJECT-17013076
  • [Journal Article] Neuromuscular abundance of RB1CC1 contributes to the non-proliferating enlarged cell phenotype through both RB1 maintenance and TSC1 degradation.2006

    • Author(s)
      Chano T., Saji M., Inoue H., Minami K., Kobayashi T., Hino O., Okabe H.
    • Journal Title

      Int. J. Molecular Medicine 18

      Pages: 425-432

    • Data Source
      KAKENHI-PROJECT-17013076
  • [Journal Article] Malignant perivascular epithelioid cell tumor of the colon : report of a case with molecular analysis2006

    • Author(s)
      Yamamoto H, Oda Y, Yao T, Oiwa T, Kobayashi C, Tamiya S, Kawaguchi K, Hino O, Tsuneyoshi M.
    • Journal Title

      Pathol Int 56

      Pages: 46-50

    • NAID

      10017321109

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500222
  • [Journal Article] Blood tests for Asbestos-related mesothelioma.2006

    • Author(s)
      Maeda M., Hino O.
    • Journal Title

      Oncology 71

      Pages: 26-31

    • Data Source
      KAKENHI-PROJECT-17013076
  • [Journal Article] Natural history of the Nihon (Bhd gene mutant) rat, a novel model for human Birt-Hogg-Dube syndrome.2006

    • Author(s)
      Kouchi M., Okimoto K., Matsumoto I., Tanaka K., Yasuba M., Hino O.
    • Journal Title

      Virchow Archives 448

      Pages: 463-471

    • Data Source
      KAKENHI-PROJECT-17013076
  • [Journal Article] Interaction of FoxO1 and TSC2 induces insulin resistance through activation of the mammalian target of rapamycin/p70 S6K pathway2006

    • Author(s)
      Cao Y, Kamioka Y, Yokoi N, Kobayashi T, Hino O, Onodera M, Mochizuki N, Nakae J.
    • Journal Title

      J Biol Chem 281

      Pages: 40242-40251

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500222
  • [Journal Article] Neuromuscular abundance of RB1CC1 contributes to the non-proliferating enlarged cell phenotype through both RB1 maintenance and TSC1 degradation2006

    • Author(s)
      Chano T, Saji M, Inoue H, Minami K, Kobayashi T, Hino O, Okabe H.
    • Journal Title

      Int J Mol Med 18

      Pages: 425-432

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500222
  • [Journal Article] Gene Expression Profile of dbpA(DNA Binding Protein A)transgenic mice2006

    • Author(s)
      Tobita, H., Kajino, K., Inami, I., Kano, S., Yasen, M., Imamura, O., Kinoshita, Y., Hino, O
    • Journal Title

      Int J Oncol 29

      Pages: 673-679

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590748
  • [Journal Article] A novel tumor marker, Niban, is expressed in subsets of thyroid tumors and Hashimoto's thyroiditis2006

    • Author(s)
      Matsumoto F, Fujii H, Abe M, Kajino K, Kobayashi T, Matsumoto T, Ikeda K, Hino O.
    • Journal Title

      Hum Pathol 37

      Pages: 1592-1600

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500222
  • [Journal Article] Interaction of FoxO1 and TSC2 induces insulin resistance through activation of the mammalian target of rapamycin/p70 S6K pathway.2006

    • Author(s)
      Cao Y, Kamioka Y, Yokoi N, Kobayashi T, Hino O, et al.
    • Journal Title

      J Biol Chem. 281・52

      Pages: 40242-51

    • Data Source
      KAKENHI-PROJECT-18500330
  • [Journal Article] Natural history of the Nihon (Bhd gene mutant) rat, a novel model for human Birt-Hogg-Dube(BHD) syndrome.2006

    • Author(s)
      Kouchi, Mami, Okimoto, Kazuo, Matsumoto, Izumi, Tanaka, Kohji, Yasuba, Masashi, Hino, Okio
    • Journal Title

      Virchow Archives 488・4

      Pages: 463-471

    • Data Source
      KAKENHI-PROJECT-17800004
  • [Journal Article] Genetic and environmental factors in hereditary predisposition to tumors : a conceptual overview2006

    • Author(s)
      Hino O, Kobayashi T, Okimoto K.
    • Journal Title

      EXS 96

      Pages: 269-292

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500222
  • [Journal Article] 単一遺伝子病とゲノム 遺伝性悪性腫瘍 結節性硬化症.2006

    • Author(s)
      樋野興夫, 小林敏之
    • Journal Title

      ゲノム医学 6

      Pages: 89-94

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17500222
  • [Journal Article] A novel ELISA system for detection of a "N-ERC/Mesothelin" in the sera of mesothelioma patients.2006

    • Author(s)
      Shiomi, K., Miyamoto, H., Segawa, T., Hagiwara, Y., Ota, A., Maeda., M., Takahashi, K., Masuda, K., Sakao, Y., Hino, O.
    • Journal Title

      Cancer Sci. (in press)

    • NAID

      10018767738

    • Data Source
      KAKENHI-PROJECT-17800004
  • [Journal Article] Genetic and environmental factors in hereditary predisposition to tumors : a conceptual overview. Cancer. Cell Structures, Carcinogens and Genomic In stability.2006

    • Author(s)
      Hino O., Kobayashi T., Okimoto K.
    • Journal Title

      Edited by Leon P. Bignold. (in press)

    • Data Source
      KAKENHI-PROJECT-17800004
  • [Journal Article] Intraction of Fox01 and TSC2 induces insulin resistance through activation of the mammalian target of rapamycin/p70 S6K pathway.2006

    • Author(s)
      Cao Y., Kamioka Y., Yokoi N., Kobayashi T., Hino O., Onodera M., Mochizuki N., Nakae J.
    • Journal Title

      J. Biological Chemistry 281

      Pages: 40242-40251

    • Data Source
      KAKENHI-PROJECT-17013076
  • [Journal Article] Transgenic rescue from embryonic lethality and renal carcinogenesis in the Nihon rat model by introduction of a wild-type Bhdgene.2006

    • Author(s)
      Togashi Y, Kobayashi T, Momose S, Ueda M, Okimoto K, Hino O
    • Journal Title

      Oncogene 25・20

      Pages: 2885-2889

    • Data Source
      KAKENHI-PROJECT-17800004
  • [Journal Article] Model animals with a tuberous sclerosis gene(Tsc1/Tsc2) mutation2005

    • Author(s)
      Kobayashi T, Hino O.
    • Journal Title

      Molec Medi 42

      Pages: 1038-1043

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500222
  • [Journal Article] Genetic analysis of Pten and Tsc2 functional interactions in the mouse reveals asymmetrical haploinsufficiency in tumor.2005

    • Author(s)
      Ma L., Teruya-Feldstein J., Behrendt N., Chen Z., Noda T., Hino O., Cordon-Cardo C., Pandolli P.P.
    • Journal Title

      Genes & Development 19

      Pages: 1779-1986

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390121
  • [Journal Article] Gene Expression Profile of dbpA (DNA Binding Protein A) transgenic mice.2005

    • Author(s)
      Tobita H., Hino O., et al.
    • Journal Title

      Int. J. Oncology (In press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390121
  • [Journal Article] A mutation in the SDHC gene of complex II increases oxidative stress, resulting in apoptosis and tumorigenesis.2005

    • Author(s)
      Ishii T., Yasuda K., Akatsuka A., Hino O., Hartman P.S., Ishii N.
    • Journal Title

      Cancer Research 65

      Pages: 203-209

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390121
  • [Journal Article] Genetic analysis of Pten and Tsc2 functional interactions in the mouse reveals asymmetrical haploinsufficiency in tumor.2005

    • Author(s)
      Ma L., Hino O.et al.
    • Journal Title

      Genes & Development 19

      Pages: 1779-1986

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390121
  • [Journal Article] Federal headship of human hepatocarcinogenesis.2005

    • Author(s)
      Hino O.
    • Journal Title

      In New Perspectives in Cancer Research and Therapy. Research Signpost (Edited Shigeki Kuriyama, Hitoshi Yoshiji)

      Pages: 125-130

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390121
  • [Journal Article] Histogenesis of LAM and MMPH. Looking at the current status of gene examination(in Japanese)2005

    • Author(s)
      Maruyama H, Hino O.
    • Journal Title

      Molec Resp Dis 9

      Pages: 420-425

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500222
  • [Journal Article] The up-regulation of Y box binding proteins (dbpA and YB-1) as prognostic markers of hepatocellular carcinoma.2005

    • Author(s)
      Yasen M., Kajino K., Kano S., Tobita H., Yamamoto J., Uchiumi T., Kon S., Hino O.et al.
    • Journal Title

      Clinical Cancer Research 11

      Pages: 7354-7361

    • Data Source
      KAKENHI-PROJECT-16390121
  • [Journal Article] Genetic analysis of Pten and Tsc2 functional interactions in the mouse reveals asymmetrical haploinsufficiency in tumor suppression2005

    • Author(s)
      Ma L, Teruya-Feldstein J, Behrendt N, Chen Z, Noda T, Hino O, Cordon-Cardo C, Pandolfi PP.
    • Journal Title

      Gene Dev 19

      Pages: 1779-1786

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500222
  • [Journal Article] Genetic analysis of Pten and Tsc2 functional interactions in the mouse reveals asymmetrical haploinsufficiency in tumor.2005

    • Author(s)
      Ma L., Teruya-Feldstein J., Behrendt N., Chen Z., Noda T., Hino O.et al.
    • Journal Title

      Genes & Development 19

      Pages: 1779-1986

    • Data Source
      KAKENHI-PROJECT-17013076
  • [Journal Article] Genetic analysis of Pten and Tsc2 functional interactions in the mouse reveals asymmetrical haploinsufficiency in tumor.2005

    • Author(s)
      Ma L., Teruya-Feldstein J., Behrendt N., Chen Z., Noda T., Hino O., Cordon-Cardo C., Pandolfi P.P.
    • Journal Title

      Genes & Development 19

      Pages: 1779-1986

    • Data Source
      KAKENHI-PROJECT-17013076
  • [Journal Article] The up-regulation of Y box binding proteins (dbpA and YB-1) as prognostic markers of hepatocellular carcinoma.2005

    • Author(s)
      Yasen M., Hino O.et al.
    • Journal Title

      Clinical Cancer Research 11

      Pages: 7354-7361

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390121
  • [Journal Article] The up-regulation of Y box binding proteins (dbpA and YB-1) as prognostic markers of hepatocellular carcinoma.2005

    • Author(s)
      Yasen M., Kajino K., Kano S., Tobita H., Yamamoto J., Uchiumi T., Kon S., Maeda M., Obulhasim G., Arii S., Hino O.
    • Journal Title

      Clinical Cancer Research 11

      Pages: 7354-7361

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390121
  • [Journal Article] A mutation in the SDHC gene of complex II increases oxidative stress, resulting in apoptosis and tumorigenesis.2005

    • Author(s)
      Ishii T., Yasuda K., Akatsuka A., Hino O., Hartman P.S., Ishii N.
    • Journal Title

      Cancer Research 65

      Pages: 203-209

    • Data Source
      KAKENHI-PROJECT-17013076
  • [Journal Article] Intentional delay of human hepatocarcinogenesis due to suppression of chronic hepatitis.2005

    • Author(s)
      Hino O.
    • Journal Title

      Intervirology 48

      Pages: 6-9

    • Data Source
      KAKENHI-PROJECT-17013076
  • [Journal Article] Genetic analysis of Pten and Tsc2 functional interactions in the mouse reveals asymmetrical haploinsufficiency in tumor.2005

    • Author(s)
      Ma L., Teruya-Feldstein J., Behrendt N., Chen Z., Noda T., Hino O.et al.
    • Journal Title

      Genes & Development 19

      Pages: 1779-1986

    • Data Source
      KAKENHI-PROJECT-16390121
  • [Journal Article] Transgenic rescue from embryonic lethality and renal carcinogenesis in the Nihon rat model by introduction of a wild-type Bhd gene.2005

    • Author(s)
      Togashi Y, Hino O., et al.
    • Journal Title

      Oncogene (In press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390121
  • [Journal Article] Intentional delay of human hepatocarcinogenesis due to suppression of chronic hepatitis.2005

    • Author(s)
      Hino O.
    • Journal Title

      Intervirology 48

      Pages: 6-9

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390121
  • [Journal Article] 「肺LAMを探る 分子生物学から臨床まで」 LAMのhistogenesisとM'MPH 遺伝子検索の現状をみる.2005

    • Author(s)
      丸山博司, 樋野興夫
    • Journal Title

      分子呼吸器病 9

      Pages: 420-425

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17500222
  • [Journal Article] Intentional delay of human hepatocarcinogenesis due to suppression on chronic hepatitis.2005

    • Author(s)
      Hino O.
    • Journal Title

      Intervirology 48

      Pages: 6-9

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390121
  • [Journal Article] これからの疾患モデル動物 家族性腫瘍 結節性硬化症遺伝子(Tsc1/Tsc2)変異モデル動物2005

    • Author(s)
      小林敏之, 樋野興夫
    • Journal Title

      Molecular Medicine 42

      Pages: 1038-1043

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17500222
  • [Journal Article] A mutation in the SDHC gene of complex II increases oxidative stress, resulting in apoptosis and tumorigenesis.2005

    • Author(s)
      Ishii T., Yasuda K., Akatsuka A., Hino O., Hartman P.S., Ishii N.
    • Journal Title

      Cancer Res 65

      Pages: 203-209

    • Data Source
      KAKENHI-PROJECT-17013076
  • [Journal Article] 癌発生観-過渡期の指導原理と新時代の形成力2004

    • Author(s)
      樋野 興夫
    • Journal Title

      日本消化器病学会雑誌 101

      Pages: 855-859

    • NAID

      10013548727

    • Data Source
      KAKENHI-PROJECT-14310014
  • [Journal Article] A germline insertion in the Birt-Hogg-Dube' (BHD) gene gives rise to the Nihon Rat model of inherited renal cancer.2004

    • Author(s)
      Okimoto K., Sakurai J., Kobayashi T., Mitani H., Hirayama Y., Nickerson M.L., Warren M.B., Zbar B., Schmidt L.S., Hino 0.
    • Journal Title

      Proc Natl Acad Sci USA 101

      Pages: 2023-2027

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12213139
  • [Journal Article] Studies of familial tumors using models : genotype, phenotype, and dramatype in carcinogenesis.2004

    • Author(s)
      Hino O.et al.
    • Journal Title

      Int.J.Clin.Oncol. 9

      Pages: 257-261

    • NAID

      10013569400

    • Data Source
      KAKENHI-PROJECT-16390121
  • [Journal Article] 基礎の立場から-俯瞰的な「家族性腫瘍学」2004

    • Author(s)
      樋野 興夫
    • Journal Title

      家族性腫瘍 5

      Pages: 2-4

    • NAID

      130007539462

    • Data Source
      KAKENHI-PROJECT-14310014
  • [Journal Article] Absence of allelic loss in cytomegalic neurons of cortical tuber in the Eker rat model of tuberous sclerosis.2004

    • Author(s)
      Mizuguchi M., Mori M., Nozaki Y., Momoi M.Y., Itoh M., Takashima S., Hino 0.
    • Journal Title

      Acta Neuropathol (Berl) 107

      Pages: 47-52

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12213139
  • [Journal Article] 家族性腫瘍とゲノム 特集にあたって2004

    • Author(s)
      樋野 興夫
    • Journal Title

      ゲノム医学 4

      Pages: 124-125

    • Data Source
      KAKENHI-PROJECT-14310014
  • [Journal Article] Multistep renal carcinogenesis in the Eker (Tsc 2 gene mutant) rat model.2004

    • Author(s)
      Hino O.et al.
    • Journal Title

      Current Molecular Medicine 4

      Pages: 807-811

    • Data Source
      KAKENHI-PROJECT-12213139
  • [Journal Article] The Niban gene is commonly expressed in renal tumors : A new candidate marker for renal carcinogenesis.2004

    • Author(s)
      Adachi H., Majima S., Kon S., Kobayashi T., Kajino K., Mitani H., Shiina H., Igawa M., Hino O.
    • Journal Title

      Oncogene 23

      Pages: 3495-3500

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12213139
  • [Journal Article] Multistep renal carcinogenesis in the Eker (Tsc 2 gene mutant) rat model.2004

    • Author(s)
      Hino O.et al.
    • Journal Title

      Current Molecular Medicine 4

      Pages: 807-811

    • Data Source
      KAKENHI-PROJECT-16390121
  • [Journal Article] Studies of familial tumors using models : genotype, phenotype, and dramatype in carcinogenesis.2004

    • Author(s)
      Hino O.et al.
    • Journal Title

      Int.J.Clin.Oncol. 9

      Pages: 257-261

    • NAID

      10013569400

    • Data Source
      KAKENHI-PROJECT-12213139
  • [Journal Article] Hereditary renal carcinogenesis fitting Knudson's two-hit model : genotype, environment, and phenotype.2003

    • Author(s)
      Hino O
    • Journal Title

      Genes Chromosomes Cancer 38

      Pages: 357-367

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12213139
  • [Journal Article] Ets protein Elf-1 bidirectionally suppresses transcriptional activities of the tumor suppressor Tsc2 gene and the repair-related Nth1 gene.2003

    • Author(s)
      Honda S., Kobayashi T., Kajino K., Urakami S., Igawa M., Hino 0.
    • Journal Title

      Mo1 Carcinog 37

      Pages: 122-129

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12213139
  • [Journal Article] Hereditary renal carcinogenesis fitting Knudson's two-hit model : genotype, environment, and phenotype.2003

    • Author(s)
      Hino 0.
    • Journal Title

      Genes Chromosomes Cancer 38

      Pages: 357-367

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12213139
  • [Journal Article] Renal carcinogenesis : genotype, phenotype and dramatype.2003

    • Author(s)
      Hino 0., Kobayashi T., Momose S., Kikuchi Y., Adachi H., Okimoto K.
    • Journal Title

      Cancer Sci 94

      Pages: 142-147

    • NAID

      10016247074

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12213139
  • [Journal Article] Renal carcinogenesis : genotype, phenotype and dramatype.2003

    • Author(s)
      Hino O.et al.
    • Journal Title

      Cancer Sci 94

      Pages: 142-147

    • NAID

      10016247074

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12213139
  • [Journal Article] Tsc tumor suppressor proteins antagonize amino-acid-TOR signaling.2002

    • Author(s)
      Gao, X., Zhang, Y., Arrazola, P., Hino, 0., Kobayashi, T., Yeung, R.S., Ru, B., Pan, D.
    • Journal Title

      Nature Cell Biology 4

      Pages: 699-704

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12213139
  • [Journal Article] Identification of the coding sequences responsible for Tsc 2-mediated tumor suppression using a transgenic rat system.2002

    • Author(s)
      Momose, S., Kobayashi, T., Mitani, H., Hirabayashi, M., Ito, K., Ueda, M., Nabeshima, Y., Hino, 0.
    • Journal Title

      Human Molecular Genetics, 11

      Pages: 2997-3006

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12213139
  • [Journal Article] Multistep renalcarcinogenesis as gene expression disease in tumor suppressor TSC2 gene mutant model-genotype, phenotype and environment.2001

    • Author(s)
      Hino, O.et al.
    • Journal Title

      Mutation Res. 477

      Pages: 155-164

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12213139
  • [Journal Article] Multistep renalcarcinogenesis as gene expression disease in tumor suppressor TSC2 gene mutant model-genotype, phenotype and environment.2001

    • Author(s)
      Hino, 0., Majima, S., Kobayashi, T., Honda, S., Momose, S., Kikuchi, Y., Mitani, H.
    • Journal Title

      Mutation Res 477

      Pages: 155-164

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12213139
  • [Journal Article] A germ-line Tscl mutation causes tumor development and embryonic lethality that are similar, but not identical to, those caused by Tsc2 mutation in mice.2001

    • Author(s)
      Kohayashi, T., Minowa, 0., Sugitani, Y., Takai, S., Mitani, H, Kobayashi, E, Noda, T., Hino, 0.
    • Journal Title

      Proc.Natl.Acad.Sci.USA 98

      Pages: 8762-8767

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12213139
  • [Journal Article] Transgenic rescue from embryonic lethality and renal carcinogenesis in the Nihon rat model by introduction of a wild-type Bhd gene.

    • Author(s)
      Togashi Y, Kobayashi T, Momose S, Ueda M, Okimoto K, Hino O
    • Journal Title

      Oncogene (in press)

    • Data Source
      KAKENHI-PROJECT-16390121
  • [Journal Article] Fenton reaction induced cancer in wild type rats recapitulates genomic alterations observed in human cancer

    • Author(s)
      Akatsuka S., Yamashita Y., Ohara H., Liu Y-T., Izumiya M., Abe K., Ochiai M., Jiang L., Nagai H., Okazaki Y., Murakami H., Sekido Y., Arai E., Kanai Y., Hino O., Takahashi T., Nakagama H. and Toyokuni S.
    • Journal Title

      PloSONE

      Volume: (in press)

    • Data Source
      KAKENHI-PROJECT-22240093
  • [Journal Article] Gene Expression Profile of dbpA (DNA Binding Protein A) transgenic mice.

    • Author(s)
      Tobita H, Kajino K, Inami K, Kano S, Yasen M, Imamura O, Kinoshita Y, Hino O.
    • Journal Title

      Int.J.Oncology (in press)

    • Data Source
      KAKENHI-PROJECT-17013076
  • [Journal Article] Natural history of the Nihon (Bhd gene mutant) rat, a novel model for human Birt-Hogg-Dube syndrome.

    • Author(s)
      Kouchi M., Okimoto K., Matsumoto I., Tanaka K., Yasuba M., Hino O.
    • Journal Title

      Virchow Archives (in press)

    • Data Source
      KAKENHI-PROJECT-17013076
  • [Journal Article] The N-ERC index is a novel monitoring and prognostic marker for advanced malignant pleural mesothelioma

    • Author(s)
      Mori T., Tajima K., Hirama M., Sato T., Kido K., Iwakami S., Sasaki S., Iwase A., Shiomi K., Maeda M., Hino O. and Takahashi K.
    • Journal Title

      J. Thoracic Disease

      Volume: (in press)

    • Data Source
      KAKENHI-PROJECT-22240093
  • [Journal Article] Transgenic rescue from embryonic lethality and renal carcinogenesis in the Nihon rat model by introduction of a wild-type Bhdgene.

    • Author(s)
      Togashi Y, Kobayashi T, Momose S, Ueda M, Okimoto K, Hino O
    • Journal Title

      Oncogene (in press)

    • Data Source
      KAKENHI-PROJECT-17800004
  • [Journal Article] Gene Expression Profile of dbpA (DNA Binding Protein A) transgenic mice.

    • Author(s)
      Tobita H, Kajino K, Inami K, Kano S, Yasen M, Imamura O, Kinoshita Y, Hino O.
    • Journal Title

      Int.J.Oncology (in press)

    • Data Source
      KAKENHI-PROJECT-16390121
  • [Journal Article] Transgenic rescue from embryonic lethality and renal carcinogenesis in the Nihon rat model by introduction of a wild-type Bhd gene.

    • Author(s)
      Togashi Y, Kobayashi T, Momose S, Ueda M, Okimoto K, Hino O
    • Journal Title

      Oncogene (in press)

    • Data Source
      KAKENHI-PROJECT-17013076
  • [Journal Article] Development of positron emission tomography imaging by 64Cu-labeled Fab for detecting ERC/mesothelin in mesothelioma mouse model.

    • Author(s)
      Yoshida C., Sogawa C., Tsuji A., Sudo H., Sugyo A., Uehara T., Hino O., Yoshii Y., Fujibayashi Y., Fukumura T., Koizumi M., Arano Y., Saga T.
    • Journal Title

      Nuclear Medicine Communications (in press)

    • Data Source
      KAKENHI-PROJECT-17013076
  • [Journal Article] Ikaros is a critical target during simultaneous exposure to X-rays and N-ethyl-N-nitrosourea in mouse T-cell lymphomagenesis

    • Author(s)
      Hirano S., Kakinuma S., Amasaki Y., Nishimura M., Imaoka T., Fujimono S., Hino O. and Shimada Y
    • Journal Title

      International J. Cancer

      Volume: (in press)

    • Data Source
      KAKENHI-PROJECT-23659206
  • [Journal Article] Natural history of the Nihon (Bhd gene mutant) rat, a novel model for human Birt-Hogg一Dube (BHD) syndrome.

    • Author(s)
      Kouchi, Mami, Okimoto, Kazuo, Matsumoto, Izumi, Tanaka, Kohji, Yasuba, Masashi, Hino, Okio
    • Journal Title

      Virchow Archives (in press)

    • Data Source
      KAKENHI-PROJECT-17800004
  • [Journal Article] Transgenic rescue from embryonic lethality and renal carcinogenesis in the Nihon rat model by introduction of a wild-type Bhd gene.

    • Author(s)
      Togashi Y, Kobayashi T, Momose S, Ueda M, Okimoto K, Hino O.
    • Journal Title

      Oncogene (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390121
  • [Journal Article] Gene Expression Profile of dbpA (DNA Binding Protein A) transgenic mice.

    • Author(s)
      Tobita H, Kajino K, Inami K, Kano S, Yasen M, Imamura O, Kinoshita Y, Hino O.
    • Journal Title

      Int.J.Oncology (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390121
  • [Journal Article] C-ERC/mesothelin provokes lymphatic invasion of colorectal adenocarcinoma

    • Author(s)
      Kawamata F., Homma S., Kamachi H., Einama T., Kato Y., Tsuda M., Tanaka S., Maeda M., Kajino K., Hino O., Takahashi N., Kamiyama T., Nishihara H., Taketomi A. and Todo S.
    • Journal Title

      J. Gastroenterology

      Volume: (in press)

    • NAID

      120005537455

    • Data Source
      KAKENHI-PROJECT-22240093
  • [Journal Article] Genetic and environmental factors in hereditary predisposition to tumors : a conceptual overview. Cancer : Cell Structures, Carcinogens and Genomic Instability.

    • Author(s)
      Hino 0., Kobayashi T., Okimoto K.
    • Journal Title

      Edited by Leon P.Bignold. (in press)

    • Data Source
      KAKENHI-PROJECT-17800004
  • [Journal Article] Clinical and genetic spectrum of Birt-Hogg-Dube syndrome patients in whom pneumothorax and/or multiple lung cysts are the presenting feature.

    • Author(s)
      Kunogi M., Kurihara M., Shigihara-Ikegami T., Kobayashi T., Shindo N., Kumasaka T., Gunji Y., Kikkawa M., Iwakami S., Hino O., Takahashi K., Seyama K.
    • Journal Title

      J. Med. Genetics (in press)

    • Data Source
      KAKENHI-PROJECT-17013076
  • [Patent] 中皮種診断剤、中皮種診断キットおよび中皮種診断方法

    • Inventor(s)
      樋野興夫、清藤勉
    • Industrial Property Rights Holder
      株式会社免疫生物研究所
    • Industrial Property Number
      2006-331409
    • Data Source
      KAKENHI-PROJECT-17013076
  • [Presentation] A novel method for highly sensitive, facile and inexpensive quantitative assessment of aberrant DNA methylation in liquid biopsies2020

    • Author(s)
      Sachio Nomura, Toshiyuki Kobayashi, Kiichi Sugimoto, Masami Arai, Kazuhiro Sakamoto, Thomas R. Pisanic II, Okio Hino.
    • Organizer
      AACR Annual Meeting 2020
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K07153
  • [Presentation] Suffering of the female cancer patient informed of recurrence who has multiple problems for mother and child relations2019

    • Author(s)
      Akemi Kurihara, Okio Hino
    • Organizer
      Annual Meeting on Supportive Care In Cancer
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15933
  • [Presentation] 母親役割をもつがん患者の不安2018

    • Author(s)
      栗原明美、樋野興夫
    • Organizer
      第23回日本緩和医療学会
    • Data Source
      KAKENHI-PROJECT-16K15933
  • [Presentation] Grief caused by the death of female cancer patients:daughters perspectives2018

    • Author(s)
      栗原明美, 樋野興夫
    • Organizer
      Global Academic Programs Conference 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15933
  • [Presentation] Highly Sensitive DNA Methylation Analysis of MLH1 and BRCA12017

    • Author(s)
      野村幸男、 樋野興夫、新井正美
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-16K07153
  • [Presentation] A new approach to the tumor suppression by an anti-erbB-2 trifunctional antibody. Poster Session2016

    • Author(s)
      Kato Y, Hirata H, Tsujisaki M, Matsune T, Adachi Y, Hinoda Y, Sasaki S, Imai K.
    • Organizer
      10th Joint Conference of the American Association for Cancer Research(AACR)and the Japanese Cancer Association(JCA)
    • Place of Presentation
      Maui, Hawaii, U.S.A.
    • Year and Date
      2016-02-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] がん哲学外来~思いありのある、人生を位置づける 処方箋。2015

    • Author(s)
      樋野興夫
    • Organizer
      市立砺波総合病院 創立記念講演会
    • Place of Presentation
      市立砺波総合病院(富山県砺波市)
    • Year and Date
      2015-04-16
    • Invited
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] Genefic effect by dysfunctional variants of ABCG2 is tronger than environmental effects for hyperuricemia2015

    • Author(s)
      Nakayama A, Matsuo H, Nakaoka H, Nakamura T, Nakashima H, Takada Y, Oikawa Y, Takada T, Sakiyama M, Shimizu S, Chiba T, Wakai K, Kawai S, Okada R, Tamura T, Shichijo Y, Akashi A, Sakurai Y, Ichida K, Shinomiya N
    • Organizer
      第25回日本疫学会学術総会
    • Place of Presentation
      ウインクあいち(愛知県・名古屋市)
    • Year and Date
      2015-01-23
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] 新渡戸稲造とがん哲学外来~純度の高い専門性と社会的包容力~。2015

    • Author(s)
      樋野興夫
    • Organizer
      新渡戸稲造「武士道」出版115周年記念シンポジウム
    • Place of Presentation
      札幌グランドホテル(北海道札幌市)
    • Year and Date
      2015-04-19
    • Invited
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] がん哲学外来の心得~温かい手・温かい心・温かい笑顔~。2015

    • Author(s)
      樋野興夫
    • Organizer
      第メディカルカフェ
    • Place of Presentation
      近畿大学(大阪府東大阪市)
    • Year and Date
      2015-04-17
    • Invited
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] Gene-trap mutagenesis is useful for analysis of long intergenic non-coding RNA genes.2015

    • Author(s)
      Nakahara, M., Yoshinobu, K., Ito, H., Furuhata, R., Yamamura, K., Araki, M. and Araki, K.
    • Organizer
      the 29th Annual Conference of the International Mammalian Genome Society
    • Place of Presentation
      横浜市開港記念会館(神奈川県横浜市)
    • Year and Date
      2015-11-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] ABCG2 gysfunction causes not only renal urate overload hyperuricemia but also renal-urate underexcretion hyperuricemia2015

    • Author(s)
      Matsuo H, Nakayama A, Sakiyama M, Chiba T, Shimazu S, Nakashima H, Nakamura T, Takada Y, Takada T, Nakaoka H, Wakai K, Kawai S, Tin G, Nakagawa H, Ito T, Yamamoto K, Sakurai Y, Ichida K, Shimizu T, Shinomiya N
    • Organizer
      第25回日本疫学会学術総会
    • Place of Presentation
      ウインクあいち(愛知県・名古屋市)
    • Year and Date
      2015-01-23
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] A combination of the anti-fibroblast growth factor receptor 1 monoclonal antibody and interferon-a/b supresses human hepatic cancer cells in vitro and in vivo2014

    • Author(s)
      Kato Y, Hiromi H, Tujisaki M, Matsune T, Sasaki S, Hinoda Y, Shinomura Y, Imai K
    • Organizer
      41 Congress of the International Society of Oncology and Biomarkers
    • Place of Presentation
      Barcelona, Spain
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] p53 family network and tumor suppression2014

    • Author(s)
      Sasaki Y, Tamura, M, Takeda K, Idogawa M, Maruyama R, Suzuki H, Shinomura Y, Tokino T
    • Organizer
      The 3rd International Symposium on Genetic Regulation and Targeted Therapy of Cancer and 5th Symposium of A3 Foresight Program
    • Place of Presentation
      Zhangjiajie, China
    • Year and Date
      2014-06-13
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] ERC/mesothelinの最近の話題2013

    • Author(s)
      樋野興夫
    • Organizer
      第5回関東中皮腫症例検討会
    • Place of Presentation
      東京
    • Year and Date
      2013-01-22
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] Dysregulation of noncoding RNA genes and its clinical application.2013

    • Author(s)
      Suzuki H, Yamamoto E, Shinomura Y and Imai K.
    • Organizer
      Ninth AACR-Japanese Cancer Association Joint Conference “Breakthroughs in Basic and Translational Cancer Research”
    • Place of Presentation
      the Hyatt Regency Maui, Maui, HI, USA.
    • Year and Date
      2013-02-21
    • Invited
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] Trans-Pacific variation in outcomes for men treated with primary androgen deprivation therapy for localized prostate cancer2013

    • Author(s)
      Cooperberg M, Hinotsu S, Namiki M, Carroll P, Akaza H
    • Organizer
      2013 AUA Annual Meeting
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] 中皮腫の早期診断と新規治療法の開発―大規模研究型検診―2013

    • Author(s)
      樋野興夫
    • Organizer
      平成24年度文部科学省がんプロフェッショナル養成基盤推進プラン採択事業 「先導的国際がん研究の動向」アスベスト暴露による中皮腫~環境発がんリスク予知と予防への新しい展開~
    • Place of Presentation
      東京
    • Year and Date
      2013-02-28
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] 中皮腫 発症前診断の取り組み2012

    • Author(s)
      樋野興夫
    • Organizer
      第3回「次世代の環境発がんを考える会」 ―「中皮腫の早期診断と新規治療法の開発」―
    • Place of Presentation
      東京
    • Year and Date
      2012-08-01
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] 「遺伝性がんモデル」から「環境発がんモデル」への展開2012

    • Author(s)
      樋野興夫
    • Organizer
      発生工学・疾患モデル研究会終了記念講演会
    • Place of Presentation
      東京
    • Year and Date
      2012-10-23
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] 次世代のがんプロに期待するもの2012

    • Author(s)
      樋野興夫
    • Organizer
      順天堂大学 医療維新をめざすICT研究者教育プラン キックオフシンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2012-06-18
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] dbpA as the stress responsive protein in hepatocarcinogenesis2007

    • Author(s)
      Inami, K., Kajino, K., Tobita, H., and Hino, O
    • Organizer
      15 th DDW Japan
    • Place of Presentation
      Kobe
    • Year and Date
      2007-10-19
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590748
  • [Presentation] dbpA Tgマウスの肝発癌;形態的変化のない初期過程で発現の変化する遺伝子群2007

    • Author(s)
      稲見 晃一, 梶野 一徳, 飛田 博史, 樋野 興夫
    • Organizer
      第15回日本消化器関連学会週間
    • Place of Presentation
      神戸国際展示場
    • Year and Date
      2007-10-19
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590748
  • [Presentation] 肝発癌過程に関与するdbpAのストレス応答蛋白としての性質2007

    • Author(s)
      稲見 晃一, 梶野 一徳, 飛田 博史, 樋野 興夫
    • Organizer
      第15回日本消化器関連学会週間(JDDW2007)
    • Place of Presentation
      神戸国際展示場
    • Year and Date
      2007-10-19
    • Data Source
      KAKENHI-PROJECT-18590748
  • [Presentation] ヒト肝癌症例におけるdbpAの発現とプロモーターメチル化による発現制御2006

    • Author(s)
      M Yasen, 梶野 一徳, 有井 滋樹, 樋野 興夫
    • Organizer
      第25回分子病理研究会
    • Place of Presentation
      東京上野水月荘
    • Year and Date
      2006-08-04
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590748
  • [Presentation] Malignant brain tumor in the cerebrum of the Eker rat model of tuberous sclerosis2005

    • Author(s)
      Mizuguchi M, Itoh M, Takashima S, Yamanouchi H, Nakazato Y, Hino O.
    • Organizer
      46th Annual Meeting of the Japanese Society of Neuropathology
    • Place of Presentation
      Utsunomiya
    • Year and Date
      2005-05-12
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500222
  • [Presentation] Pathomechanism of hamartia and tumors in tuberous sclerosis2005

    • Author(s)
      Mizuguchi M, Mori M, Nozaki Y, Itoh M, Takashima S, Hino O.
    • Organizer
      45th Annual Meeting of the Japanese Society
    • Place of Presentation
      Tokyo
    • Year and Date
      2005-07-15
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500222
  • []

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  • 275.  小池 正人
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