MURAKAMI Seishi 村上清史

Researcher Number	90019878
Other IDs
External Links
Affiliation *help	2007 : 金沢大, 名誉教授 2006 – 2007 : 金沢大学, 名誉教授 2007 : Kanazawa University, Cancer Research Institute, Emeritus Professor 2007 : Kanazawa University, 金沢大学, 名誉教授 1996 – 2006 : 金沢大, がん研究所, 教授 … More
Review Section/Research Field	Principal Investigator Molecular biology / Biological Sciences / Pathological medical chemistry / Pathological medical chemistry / 分子遺伝学・分子生理学
Keywords	Principal Investigator RPB5 / RMP / トランス活性化 / HCV NS5B / B型肝炎ウイルス / TFIIB / NS5A / 転写修飾 / RNAポリメラーゼ / HBV X蛋白 … More Except Principal Investigator X遺伝子 / 分子細胞遺伝学 / 形質細胞腫 / C型肝炎ウイルス / SCIDマウス / B型肝炎ウイルス / MCAF / p53 / 慢性肝炎 / 遺伝子発現 / HBV / Abelson leukemia virus / McAF / ウッドチャック肝癌 / 超可変領域(HVR) / gene Chronic hepatitis / receptors / トランスジェニックマウス / 染色体転座 / apoptosis / B型肝炎ウイルス(HBV) / 細胞障害性T細胞 / cMyc遺伝子 / Liver cirrhosis / hepatitis B virus / 前臨床実験 / インタ-ロイキン8 / 膵液 / NFkB siganling / 病態生理作用 / アクリジンエステル / interleukin 8 / Hepatocellular carcinoma / 染色体不安定性 / プロテアーゼインヒビター / 構造と機能 / がん抑制遺伝子 / 肝細胞癌 / 癌遺伝子1ca / X蛋白質 / 超可変領域 / inflammation / 肝硬変 / gene expression / 癌遺伝子 / MHC / Chromosomal translocation / 前駆体蛋白質プロセッシング / Leukocyte Chemotactic factors / pathophysialogical roles / predisposition / DNA組み込み / Abelson白血病ウィルス / インターロイキン8 / structural analysis / Transfection系 / Transgenic Mouse / Plasmacytoma / 転写活性化 / HPA法 / K-ras / 受容体 / アポトーシス / hepatitis C virus / 肝発がん / Cytogenetics / 細胞内局在性 / 肝炎ウイルスエンハンサーlca遺伝子 / Abelson白血病ウイルス / ウイルス性肝発がん / ダックB型肝炎ウイルス / 癌抑制遺伝子p53 / SCID mouse / 癌抑制遺伝子 / 膵癌 / サイトカイン / エンハンサー / HCV遺伝子型 / 白血球走化性因子 / C型肝炎ウイルス(HCV) / caspase activity / cytokine / DNA再編成 / 遺伝子 / 肝細胞韓 / mitochondria / Hepatitis C virus / 構造解析 / HBx protein Less

B型肝炎ウイルスX蛋白の転写修飾機能と細胞形質転換能促進Principal Investigator
- Principal Investigator
  
  村上清史
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
B型肝炎ウイルスX蛋白の転写修飾機能と細胞形質転換能促進Principal Investigator
- Principal Investigator
  
  村上清史
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
Subcellular localization and control of activity of telomerasePrincipal Investigator
- Principal Investigator
  
  MURAKAMI Seishi
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kanazawa University
Functional analysis of Hepatitis C Virus replicase NS5B and a regulatory factor NS5APrincipal Investigator
- Principal Investigator
  
  MURAKAMI Seishi
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  KANAZAWA UNIVERSITY
Function of Hepatitis B Virus X proteinPrincipal Investigator
- Principal Investigator
  
  MURAKAMI Seishi
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  KANAZAWA UNIVERSITY
DRUG DESIGINS OF INHIBITORS TARGETED TO REPLICASE AND REPLICATION OF HEPATITIS C VIRUS (HCV)Principal Investigator
- Principal Investigator
  
  MURAKAMI Seishi
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Molecular biology
- Research Institution
  Kanazawa University
新規転写補助因子RMPによる転写制御とHBV X蛋白のトランス活性化Principal Investigator
- Principal Investigator
  
  村上清史
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kanazawa University
Role of RNA polymerase, II submit 5 (RPB5) in activated transcription, and function of a novel transcriptional cofactor, RMP.Principal Investigator
- Principal Investigator
  
  MURAKAMI Seishi
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Molecular biology
- Research Institution
  KANAZAWAI UNIVERSITY
RNA-dependent RNA polymerase activity and effect on host inflammatory response of Hepatitis C Virus(HCV)NS5B.Principal Investigator
- Principal Investigator
  
  MURAKAMI Seishi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Pathological medical chemistry
- Research Institution
  KANAZAWA UNIVERSITY
新規転写補助因子RMPによる転写制御とHBvX蛋白のトランス活性化Principal Investigator
- Principal Investigator
  
  村上清史
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kanazawa University
Clarification of molecular mechanisims of hepatocellular carcinoma caused by hepatitis virus infection.
- Principal Investigator
  
  SHIMOTOHNO Kunitada
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas.
- Research Institution
  Institute for Virus Research, Kyoto University
Modulation of transcriptional machinery by hepatitis B virus X proteinPrincipal Investigator
- Principal Investigator
  
  MURAKAMI Seishi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  Molecular biology
- Research Institution
  Kanazawa University
肝炎ウイルスの増殖と肝発がん
- Principal Investigator
  
  小池克郎
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Japanese Foundation For Cancer Research
膵液中遺伝子分析による膵癌診断法の開発
- Principal Investigator
  
  澤武紀雄
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kanazawa University
Role of RNA polymerase subunit RPB 5 in transcriptional complex formation and Dranscriptional controlPrincipal Investigator
- Principal Investigator
  
  MURAKAMI Seishi
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Molecular biology
- Research Institution
  Kanazawa University
SCIDマウス系における形質細胞腫発症機構の分子細胞遺伝学的研究
- Principal Investigator
  
  大野真介
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kanazawa University
Cytogenetic Studies on the Plasmacytomagenesis in SCID mice
- Principal Investigator
  
  OHNO Shinsuke
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Cancer Research Institute Kanazawa University
肝炎ウイルスと肝発がん
- Principal Investigator
  
  小池克郎
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Japanese Foundation For Cancer Research
SCIDマウス系における形質細胞腫発症機構の分子細胞遺伝学的研究
- Principal Investigator
  
  OHNO Shinsuke, 大野真介
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kanazawa University
Hepatitis C Virus and Hepatoma between U.S.A. and Japan
- Principal Investigator
  
  KOBAYASHI Kenichi
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Kanazawa University, Faculty of Medicine
Basic and preclinical experiments of IL 8 and MCAF
- Principal Investigator
  
  MATSUSHIMA Kouji, 松島網治
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Cancer Research Institute, Kanazawa University
非A非B肝炎型ウイルスゲノムのクロ-ニングPrincipal Investigator
- Principal Investigator
  
  村上清史
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  分子遺伝学・分子生理学
- Research Institution
  Kanazawa University
肝炎ウイルスと肝癌発生Principal Investigator
- Principal Investigator
  
  村上清史
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kanazawa University
肝炎ウイルスと肝癌発生
- Principal Investigator
  
  服部信
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kanazawa University
肝炎ウイルスと肝癌発生
- Principal Investigator
  
  服部信
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kanazawa University

All 2007 2006 2001 Other

All Journal Article Presentation

[Journal Article] Mutations in Ran system affected telomere silencing in Saccharomyces cerevisiae2007
- Author(s)
  Hayashi N、 Kobayashi M, Shimizu HYamamoto K, Murakami S, Nishimoto T.
- Journal Title
  
  Biochem Biophys Res Commun 363(3)
  
  Pages : 788-794
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390091
[Journal Article] Hepatitis B Virus X protein overcomes oncogenic RAS-induced senescence in human immortalized cells.2007
- Author(s)
  Oishi N, Shilagardi K, Nakamoto Y, Honda M, Kaneko S, Murakami S.
- Journal Title
  
  Cancer Science 98(10):
  
  Pages : 1540-1548
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18012018
[Journal Article] Hepatitis B Virus X protein overcomes oncogenic RAS-induced senescence in human immortalized cells2007
- Author(s)
  Oishi N, Shilagardi K, Nakamoto Y, Honda M, Kaneko S, Murakami S.
- Journal Title
  
  Cancer Science 98(10)
  
  Pages : 1540-1548
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390091
[Journal Article] Human telomerase exists in two distinct active complexes in vivo2007
- Author(s)
  Kusakawa T, Shimakami T, Kaneko S, Yoshioka K, *Murakami S.
- Journal Title
  
  J. Biochem (Tokyo) 98(10)
  
  Pages : 917-927
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390091
[Journal Article] Human telomerase exists in two distinct active complexes in vivo.2007
- Author(s)
  Kusakawa T, Shimakami T, Kaneko S, Yoshioka K, *^Murakami S.
- Journal Title
  
  J. Biochem(Tokyo). 98(10)
  
  Pages : 917-927
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390091
[Journal Article] Mutations in Ran system affected telomere silencing in Saccharomyces cerevisiae2007
- Author(s)
  Hayashi N, Kobayashi M, Shimizu H Yamamoto K, Murakami S, Nishimoto T.
- Journal Title
  
  Biochem Biophys Res Commun. 363(3)
  
  Pages : 788-794
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390091
[Journal Article] Hepatitis B Virus X protein overcomes oncogenic RAS-induced senescence in human immortalized cells.2007
- Author(s)
  Oishi N, Shilagardi K, Nakamoto Y, Honda M, Kaneko S, Murakami S.
- Journal Title
  
  Cancer Science 98(10)
  
  Pages : 1540-1548
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390091
[Journal Article] Hepatitis B Virus X protein overcomes oncogenic RAS-induced senescence in human immortalized cells2007
- Author(s)
  Oishi, N., Khurts, S., Nakamoto, Y., Honda, M., Kaneko, S., *Murakami, S
- Journal Title
  
  Cancer Science 98(10)
  
  Pages : 1540-1548
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390091
[Journal Article] Mutations in Ran system affected telomere silencing in Saccharomyces cerevisiae2007
- Author(s)
  Hayashi, N., Kobayashi, M., Shimizu, H., Yamamoto, K., Murakami, C., Nishimoto, T
- Journal Title
  
  Biochem Biophys Res Commun 363(3)
  
  Pages : 788-794
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390091
[Journal Article] Temperature-sensitive defects of the GSP1gene, yeast Ran homologue, activate the Tel1-dependent pathway.2007
- Author(s)
  Hayashi N, Murakami S(10名)
- Journal Title
  
  Biochem Biophys Res Commun. 9(2)
  
  Pages : 330-336
- Data Source
  KAKENHI-PROJECT-18012018
[Journal Article] Temperature-sensitive defects of the GSP1gene,yeast Ran homologue,activate the Tell-dependent pathway.2007
- Author(s)
  Hayashi N, Murakami S (10名)
- Journal Title
  
  Biochem Biophys Res Commun. 9(2)
  
  Pages : 330-336
- Data Source
  KAKENHI-PROJECT-17390091
[Journal Article] Molecular functions and biological roles of hepatitis B virus x protein.2006
- Author(s)
  Tang H, Murakami S (4名)
- Journal Title
  
  Cancer Science 97(19)
  
  Pages : 977-983
- Data Source
  KAKENHI-PROJECT-17390091
[Journal Article] Effect of hepatitis C virus (HCV) NS5B-nucleolin interaction on HCV replication with HCV subgenomic replicon.2006
- Author(s)
  Shimakami T, Murakami S (7名)
- Journal Title
  
  J. Virology 80(7):
  
  Pages : 3332-3340
- Data Source
  KAKENHI-PROJECT-17390091
[Journal Article] Effect of hepatitis C virus (HCV) NS5B-nucleolin interaction on HCV replication with HCV subgenomic replicon.2006
- Author(s)
  Shimakami T, Murakami S(7名)
- Journal Title
  
  J.Virology 80(7)
  
  Pages : 3332-3340
- Data Source
  KAKENHI-PROJECT-18012018
[Journal Article] Molecular functions and biological roles of hepatitis B virus x protein.2006
- Author(s)
  Tang H, Murakami S(4名)
- Journal Title
  
  Cancer Science 97(19)
  
  Pages : 977-983
- Data Source
  KAKENHI-PROJECT-18012018
[Journal Article] Hepatitis B Virus X protein : A multifunctional regulatory protein.2001
- Author(s)
  S.Murakami
- Journal Title
  
  J.Gastroenterol. 36
  
  Pages : 651-660
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12213050
[Journal Article] Hepatitis B Virus X protein : A multifunctional regulatory protein2001
- Author(s)
  Murakami, S.
- Journal Title
  
  J.Gastroenterol. 36
  
  Pages : 651-660
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12213050
[Presentation] テロメアサイレンシングにおける出芽酵母Ran系遺伝子群の機能2007
- Author(s)
  林直之、西本毅治、村上清史、山本健一
- Organizer
  第30回日本生物学会年会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-17390091
[Presentation] Biological functions of hepatitis B virus X protein2007
- Author(s)
  Murakami S
- Organizer
  Japan-Korea Joint Symposium on Recent Advancein Medical Science
- Place of Presentation
  Chonbok Univ, Korea
- Year and Date
  2007-11-15
- Data Source
  KAKENHI-PROJECT-17390091
[Presentation] Biological functions of hepatitis B virus X protein2007
- Author(s)
  Murakami, S
- Organizer
  Japan-Korea Joint Symposium on Recent Advance in Medical Science
- Place of Presentation
  Chonbok Univ, Korea
- Year and Date
  2007-11-15
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390091
[Presentation] テロメアサイレンシングにおける出芽酵母Ran系遺伝子群の機能2007
- Author(s)
  林直之、西本毅治、村上清史、山本健一
- Organizer
  第30回日本生物学会年会
- Place of Presentation
  パシフィコ横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390091
[Presentation] Biological functions of hepatitis B virus X protein2007
- Author(s)
  Murakami S
- Organizer
  Japan-Korea Joint Symposium on Recent Advance in Medical Science
- Place of Presentation
  Chonbok Univ, Korea
- Year and Date
  2007-11-15
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390091
[Presentation] Biological functions of hepatitis B virus X protein2007
- Author(s)
  Murakami S
- Organizer
  Japan-Korea Joint Symposium on Recent Advance in Medical Science
- Place of Presentation
  Chonbok Univ, Korea
- Year and Date
  2007-11-15
- Data Source
  KAKENHI-PROJECT-18012018
[Presentation] テロメアサイレンシングにおける出芽酵母Ran系遺伝子群の機能2007
- Author(s)
  林直之、西本毅治、村上清史、山本健一
- Organizer
  第30回日本生物学会年会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-18012018
[Presentation] Functional interaction of hepatitis C virus NS5B with nucleolin GAR domain
- Author(s)
  Shimakami, T., Kusakawa, T., Honda, M., Kaneko, S., Yohioka, K., Murakami, S
- Organizer
  15th International symposium on Hepatitis C Virus & Related Viruses
- Place of Presentation
  Texas
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390091

1. HAYASHI Naoyuki (50253456)

# of Collaborated Projects : 7results

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2. KOIKE Katsurou (30085625)

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3. NOMURA Takahiro (80115261)

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6. MATSUSHIMA Kouji (50222427)

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7. HAYAKAWA Jun-ichiro (50110622)

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8. KOBAYASHI Kenichi (70019933)

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9. SHIMOTOHNO Kunitada (10000259)

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26. 鈴木健之 (30262075)

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27. 岡山博人 (40111950)

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28. 小池和彦 (90234658)

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29. 千坂修 (80188474)

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31. 吉倉廣 (60012754)

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32. 澤武紀雄 (90019969)

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33. WIENER Francis

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34. ROEDER Robert

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35. KUSAKAWA Takashi

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36. ROBERT H PUR

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37. PURCELL Robe

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38. 松島網治

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39. CHRISTIAN G.

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40. ETTORE APPEL

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41. JOOST J. OPP

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42. OPPENHEIM Joost J.

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43. LARSEN Christian

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44. APPELLA Ettore

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46. APPELLA Etto

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47. OPPENHEIM Jo

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48. FRANCIS Wien

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
49. ROEDER Robet

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
50. 大藤努

# of Collaborated Projects : 1results

# of Collaborated Products : 0results

MURAKAMI Seishi 村上 清史

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B型肝炎ウイルスX蛋白の転写修飾機能と細胞形質転換能促進Principal Investigator

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B型肝炎ウイルスX蛋白の転写修飾機能と細胞形質転換能促進Principal Investigator

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Subcellular localization and control of activity of telomerasePrincipal Investigator

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Functional analysis of Hepatitis C Virus replicase NS5B and a regulatory factor NS5APrincipal Investigator

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Function of Hepatitis B Virus X proteinPrincipal Investigator

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DRUG DESIGINS OF INHIBITORS TARGETED TO REPLICASE AND REPLICATION OF HEPATITIS C VIRUS (HCV)Principal Investigator

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新規転写補助因子RMPによる転写制御とHBV X蛋白のトランス活性化Principal Investigator

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Role of RNA polymerase, II submit 5 (RPB5) in activated transcription, and function of a novel transcriptional cofactor, RMP.Principal Investigator

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RNA-dependent RNA polymerase activity and effect on host inflammatory response of Hepatitis C Virus(HCV)NS5B.Principal Investigator

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新規転写補助因子RMPによる転写制御とHBvX蛋白のトランス活性化Principal Investigator

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Modulation of transcriptional machinery by hepatitis B virus X proteinPrincipal Investigator

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MURAKAMI Seishi 村上清史