kaneko shuuichi 金子周一

… Alternative Names

KANEKO Shuichi 金子周一

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Researcher Number	60185923
Other IDs
External Links
Affiliation (Current)	2025: 金沢大学, 医薬保健学総合研究科, 特任教授
Affiliation (based on the past Project Information) *help	2008 – 2021: Kanazawa University, 医学系, 教授 2013: 金沢大学, 大学院医薬保健学総合研究科, 教授 2004 – 2007: Kanazawa University, Graduate School of Medical Science, Professor, 医学系研究科, 教授 2004 – 2005: 金沢大学, 大学院・医学系研究科, 教授 2002 – 2003: 金沢大学, 医学系研究科, 助教授 … More 2001 – 2003: Medical school, Kanazawa University Associate Professor, 大学院・医学系研究科, 助教授 1996 – 2000: School of Medicine, Kanazawa University Associate Professor, 医学部, 助教授 1996: 秋田大学, 医学部, 助教授 1995: 金沢大学, 医学部・附属病院, 講師 1993: 金沢大学, 医学部・付属病院, 講師 1992: Kanazawa University. Faculty of Medicine, 医学部, 講師 1991: 金沢大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Gastroenterology / Gastroenterology / Biological Sciences / Complex systems / Pathological medical chemistry Except Principal Investigator Gastroenterology / 膠原病・アレルギー・感染症内科学 / Tumor biology / Urology / Virology / Tumor immunology / Community health/Gerontological nurisng
Keywords	Principal Investigator 肝臓 / DNAチップ / 慢性肝炎 / 生活習慣病 / 栄養 / 発現制御 / ゲノム / 肝細胞がん / トランスクリプトーム / 肝細胞癌 … More / アルファフェトプロテイン / 遺伝子治療 / 癌 / SAGE / C型肝炎ウイルス / 肝硬変 / DNA chip / Cancer / Hepatocellular Carcinoma / Gene Therapy / 糖尿病 / 発現遺伝子 / HCV / 遺伝子 / 肝癌 / アデノウイルス / 肝線維化 / 脂肪性肝炎 / 単純性脂肪肝 / proteome / transcriptome / diabetis / hepatocellular carcinoma / obesity / gene expression / liver / ジェノミクス / ジュノミクス / プロテオーム / 肝がん / 肥満 / Molecular Diagnosis / Biosensor / 遺伝子診断 / バイオセンサー / Phasmapheresis / Hepatitis C Virus / Chimpanzee / 血液浄化療法 / チンパンジー / Adenovirus / Alpha-fetoprotein / チミジンカイネース / アデノウイルスベクター / プロモーター / HBV / 持続感染 / ゲノミクス / 自殺遺伝子 / 抗腫瘍免疫 / マクロファージ / HSV-TK / αフェトプロテイン / 早期診断 / Genomics / 吸着体 / 血液浄化 / guasispecies … More Except Principal Investigator 肝細胞癌 / C型肝炎ウイルス / real-time PCR / STS / AZF / SAGE / Genomics / Cre / gene therapy / 遺伝子治療 / ゲノム / 悪性化 / 浸潤・転移 / がん / 肝臓 / 浸潤転移 / 膜型マトリックスメタロプロテアーゼ / Invasion / HIF / EphA2 / がん微小環境 / ラミニン / 肝細胞がん / CD90 / EpCAM / Mint3 / HIF-1 / MT1-MMP / がんの増殖・浸潤・転移 / がん幹細胞 / 肝臓がん / Expression profile / Initiation factors / Internal Ribosomal Entry Site / Hepatitis C Virus / 蛋白翻訳 / レプリコン / 蛋白飜訳 / 発現プロファイル / 翻訳開始因子 / IRES / Spermatogenesis / genome / palindrome / male infertility / Y chromosome / 精子形成遺伝子 / 無精子症 / 特発性男性不妊症 / 精子形成障害 / パリンドローム / 男性不妊症 / Y染色体 / clusteranalysis / geneexpressionprofile / DNAmicroarray / hepatocellularcarcinoma / DNA microarray / 肝臓特異的DNAチップ / 遺伝子発現パターン / DNAチップ / クラスター解析 / 遺伝子発現プロフィール / DNA microarray法 / SAGE法 / cancer-specific promoter / vector / adenovirus / 特異的プロモーター / ベクター / アデノウイルス / caspase activity / inflammation / mitochondria / HBx protein / NFkB siganling / apoptosis / hepatitis B virus / hepatitis C virus / がん抑制遺伝子 / アポトーシス / p53 / MHC / X蛋白質 / 細胞障害性T細胞 / 染色体不安定性 / B型肝炎ウイルス / ganciclovir / herpes simplex thymidine kinase / retroviral vector / hepatocellular carcinoma / ガンシクロビル / HSV-TK遺伝子 / レトロウイルスベクター / Liver cirrhosis / gene Chronic hepatitis / Hepatocellular carcinoma / Hepatitis C virus / 肝細胞韓 / 肝硬変 / 慢性肝炎 / 遺伝子 / がん特異的T細胞 / T細胞受容体 / 抗原特異的T細胞 / 細胞チップ / 細胞免疫 / C型慢性肝炎 / 肝癌 / 肝炎 / 遺伝子発現 / 末梢血単核球 / 加速度脈波 / 脳機能 / QOL / 補完・代替医療 / 生活活性化 / 生活・栄養指導 / 持続可能性 / 包括的地域ケア / 園芸療法 / 元気高齢者 / 内科 / 応用動物 / ウイルス / 癌 Less

Elucidation of inflammation cellular society in liver cirrhosisPrincipal Investigator
- Principal Investigator
  
  KANEKO Shuichi
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Kanazawa University
Analysis of MT1-MMP-dependent molecular pathways in the diversity and transformation of hepatocellular carcinoma
- Principal Investigator
  
  Seiki Motoharu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor biology
- Research Institution
  Kanazawa University
Study of the liver as an endocrine organPrincipal Investigator
- Principal Investigator
  
  KANEKO Shuichi
- Project Period (FY)
  2014 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Gastroenterology
- Research Institution
  Kanazawa University
Detection of cancer specific T cells on a chip
- Principal Investigator
  
  KISHI HIROYUKI
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor immunology
- Research Institution
  University of Toyama
Liver producing hormones and life style related diseasesPrincipal Investigator
- Principal Investigator
  
  KANEKO Shuichi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Gastroenterology
- Research Institution
  Kanazawa University
Gene expression profiling of peripheral mononuclear cells in blood and liver disease
- Principal Investigator
  
  HONDA Masao
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Kanazawa University
Disturbance of hepatic function and over nutrition-related diseasesPrincipal Investigator
- Principal Investigator
  
  KANEKO Shuichi
- Project Period (FY)
  2006 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Gastroenterology
- Research Institution
  Kanazawa University
元気高齢者に園芸療法を適用した包括的地域ケアモデルの構築と場の創造
- Principal Investigator
  
  安川緑
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Community health/Gerontological nurisng
- Research Institution
  Kanazawa University
Identification of host factors required for HCV-IRES activity and their physiological roles in liver disease
- Principal Investigator
  
  HONDA Masao
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Kanazawa University
Analysis and detecction of polymorphism of palindrome complex on Y chmmosome in idiopathic male infertility
- Principal Investigator
  
  KOH Eitetsu
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Kanazawa University
宿主免疫のトランスクリプトーム解析を用いたC型肝炎ウイルスの持続感染機序研究Principal Investigator
- Principal Investigator
  
  金子周一
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
トランスクリプトーム技術を用いた肝細胞がんの早期診段開発研究Principal Investigator
- Principal Investigator
  
  金子周一
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
B型肝炎ウイルス肝発癌モデルにおける標的分子の同定
- Principal Investigator
  
  KOBAYASHI Kenichi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Kanazawa University
肝細胞におけるFunctionalGenomics解析系の確立Principal Investigator
- Principal Investigator
  
  金子周一
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Kanazawa University
Establishment of Genomics Based HepatologyPrincipal Investigator
- Principal Investigator
  
  KANEKO Shuichi
- Project Period (FY)
  2001 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Gastroenterology
- Research Institution
  Kanazawa University
Genomicsを用いた早期肝細胞癌の診断開発研究Principal Investigator
- Principal Investigator
  
  金子周一
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
進行肝細胞癌に対する新たな遺伝子治療ベクターの開発Principal Investigator
- Principal Investigator
  
  金子周一
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Kanazawa University
Genomics of liver cells anォ liver cancer cells
- Principal Investigator
  
  KOBAYASHI Kenichi
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Gastroenterology
- Research Institution
  Kanazawa University
Development of Biosensor-type-DNA Chip for the Diagnosis of CancerPrincipal Investigator
- Principal Investigator
  
  KANEKO Shuichi
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for University and Society Collaboration
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kanazawa University
血液浄化法によるC型肝炎ウイルス除去の試みPrincipal Investigator
- Principal Investigator
  
  金子周一
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Kanazawa University
Clarification of molecular mechanisims of hepatocellular carcinoma caused by hepatitis virus infection.
- Principal Investigator
  
  SHIMOTOHNO Kunitada
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Institute for Virus Research, Kyoto University
Establishment of Gene Therapy for Advanced Hepatocellular Carcinoma with Intra- and Extra- Hepatic MetastasesPrincipal Investigator
- Principal Investigator
  
  KANEKO Shuichi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Kanazawa University
Removal of Hepatitis C Virus in the Serum of Chimpanzees by PhasmapheresisPrincipal Investigator
- Principal Investigator
  
  KANEKO Shuichi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Kanazawa University
Development of double infection method aiming at gene therapy of hepatocarcinoma.
- Principal Investigator
  
  SAITO Izumu
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  The University of Tokyo
Gene Therapy for Advanced Hepatocellular Carcinoma using Transcriptional ControlPrincipal Investigator
- Principal Investigator
  
  KANEKO Shuichi
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kanazawa University, Facutly of Medicine
Basic study of gene therapy for hepatocellular carcinoma
- Principal Investigator
  
  KOBAYASHI Kenichi
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Kanazawa University
C型肝炎ウイルス感染の慢性化機序の検討Principal Investigator
- Principal Investigator
  
  金子周一
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Gastroenterology
- Research Institution
  Kanazawa University
Hepatitis C Virus and Hepatoma between U.S.A. and Japan
- Principal Investigator
  
  KOBAYASHI Kenichi
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Kanazawa University, Faculty of Medicine

[Journal Article] Forkhead box protein O1 (FoxO1) knockdown accelerates the eicosapentaenoic acid (EPA)-mediated <i>Selenop</i> downregulation independently of sterol regulatory element-binding protein-1c (SREBP-1c) in H4IIEC3 hepatocytes2022
- Author(s)
  K Kamoshita, N Tajima-Shirasaki, KA Ishii, T Shirasaki, H Takayama, H Abuduwaili, T Abuduyimiti, HK Oo, X Yao, Q Li, CM Galicia-Medina, S Kaneko, T Takamura.
- Journal Title
  
  Endocr J
  
  Volume: 69 Issue: 8 Pages: 907-918
- DOI
  10.1507/endocrj.EJ21-0392
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06393, KAKENHI-PROJECT-17H04199, KAKENHI-PROJECT-18K08507, KAKENHI-PROJECT-21K08573, KAKENHI-PROJECT-21K19503
[Journal Article] Brown adipocyte-specific knockout of Bmal1 causes mild but significant thermogenesis impairment in mice2021
- Author(s)
  Hasan Nazmul、Nagata Naoto、Morishige Jun-ichi、Islam Md Tarikul、Jing Zheng、Harada Ken-ichi、Mieda Michihiro、Ono Masanori、Fujiwara Hiroshi、Daikoku Takiko、Fujiwara Tomoko、Maida Yoshiko、Ota Tsuguhito、Shimba Shigeki、Kaneko Shuichi、Fujimura Akio、Ando Hitoshi
- Journal Title
  
  Molecular Metabolism
  
  Volume: 49 Pages: 101202-101202
- DOI
  10.1016/j.molmet.2021.101202
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09776, KAKENHI-PROJECT-20K07020, KAKENHI-PROJECT-20K21498, KAKENHI-PROJECT-20K21651, KAKENHI-PROJECT-19H03399, KAKENHI-PROJECT-20H03822, KAKENHI-PROJECT-18K08470, KAKENHI-PLANNED-17H06393, KAKENHI-PROJECT-20H03996, KAKENHI-PROJECT-19H01617
[Journal Article] C C chemokine ligand 3 deficiency ameliorates diet-induced steatohepatitis by regulating liver macrophage recruitment and M1/M2 status in mice2021
- Author(s)
  Xu Liang、Chen Yongping、Nagashimada Mayumi、Ni Yinhua、Zhuge Fen、Chen Guanliang、Li Haoran、Pan Tongtong、Yamashita Tatsuya、Mukaida Naofumi、Kaneko Shuichi、Ota Tsuguhito、Nagata Naoto
- Journal Title
  
  Metabolism
  
  Volume: 125 Pages: 154914-154914
- DOI
  10.1016/j.metabol.2021.154914
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11764, KAKENHI-PLANNED-17H06393
[Journal Article] Serum laminin γ2 monomer as a novel diagnostic and predictive biomarker for hepatocellular carcinoma.2021
- Author(s)
  T Yamashita, N Koshikawa, T Shimakami, T Terashima, M Nakagawa, K Nio, R Horii, N Iida, K Kawaguchi, K Arai, Y Sakai, T Yamashita, E Mizukoshi, M Honda, A Kitao, S Kobayashi, S Takahara, Y Imai, K Yoshimura, T Murayama, Y Nakamoto, E Yoshida, T Yoshimura, M Seiki, S Kaneko.
- Journal Title
  
  Hepatology
  
  Volume: - Issue: 2 Pages: 760-775
- DOI
  10.1002/hep.31758
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06393, KAKENHI-PROJECT-18H02792, KAKENHI-PROJECT-18H02793, KAKENHI-PROJECT-19H03637, KAKENHI-PROJECT-21H04823, KAKENHI-PROJECT-17H01886, KAKENHI-PROJECT-21H02900, KAKENHI-PROJECT-20K16984, KAKENHI-PROJECT-16H06277, KAKENHI-PLANNED-17H06329, KAKENHI-PROJECT-21K09840
[Journal Article] CX3CL1?CX3CR1 signalling deficiency exacerbates obesity-induced inflammation and insulin resistance in male mice2021
- Author(s)
  Nagashimada Mayumi、Sawamoto Kazuki、Ni Yinhua、Kitade Hironori、Nagata Naoto、Xu Liang、Kobori Masuko、Mukaida Naofumi、Yamashita Tatsuya、Kaneko Shuichi、Ota Tsuguhito
- Journal Title
  
  Endocrinology
  
  Volume: - Issue: 6
- DOI
  10.1210/endocr/bqab064
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11764, KAKENHI-PLANNED-17H06393
[Journal Article] Artificial intelligence/neural network system for the screening of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis.2021
- Author(s)
  T Okanoue, T Shima, Y Mitsumoto, A Umemura, K Yamaguchi, Y Itoh, M Yoneda, A Nakajima, E Mizukoshi, S Kaneko, K Harada.
- Journal Title
  
  Hepatol Res
  
  Volume: - Issue: 5 Pages: 554-569
- DOI
  10.1111/hepr.13628
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06393, KAKENHI-PROJECT-18K07637
[Journal Article] LECT2 as a hepatokine links liver steatosis to inflammation via activating tissue macrophages in NASH2021
- Author(s)
  Takata Noboru、Ishii Kiyo-aki、Takayama Hiroaki、Nagashimada Mayumi、Kamoshita Kyoko、Tanaka Takeo、Kikuchi Akihiro、Takeshita Yumie、Matsumoto Yukako、Ota Tsuguhito、Yamamoto Yasuhiko、Yamagoe Satoshi、Seki Akihiro、Sakai Yoshio、Kaneko Shuichi、Takamura Toshinari
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 555-555
- DOI
  10.1038/s41598-020-80689-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08507, KAKENHI-PROJECT-19K08975, KAKENHI-PROJECT-20K17017, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06393, KAKENHI-PROJECT-17H04199, KAKENHI-PROJECT-18K06889, KAKENHI-PROJECT-18K19560, KAKENHI-PROJECT-19K23983
[Journal Article] Alcohol Intake Is Associated With Elevated Serum Levels of Selenium and Selenoprotein P in Humans2021
- Author(s)
  Isobe Yuki、Asakura Hiroki、Tsujiguchi Hiromasa、Kannon Takayuki、Takayama Hiroaki、Takeshita Yumie、Ishii Kiyo-aki、Kanamori Takehiro、Hara Akinori、Yamashita Tatsuya、Tajima Atsushi、Kaneko Shuichi、Nakamura Hiroyuki、Takamura Toshinari
- Journal Title
  
  Frontiers in Nutrition
  
  Volume: 8 Pages: 633703-633703
- DOI
  10.3389/fnut.2021.633703
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08507, KAKENHI-PROJECT-19KK0237, KAKENHI-PLANNED-17H06393, KAKENHI-PROJECT-17H04199, KAKENHI-PROJECT-18K19560
[Journal Article] Xanthine oxidase inhibition attenuates insulin resistance and diet-induced steatohepatitis in mice2020
- Author(s)
  Nishikawa Tomoki、Nagata Naoto、Shimakami Tetsuro、Shirakura Takashi、Matsui Chieko、Ni Yinhua、Zhuge Fen、Xu Liang、Chen Guanliang、Nagashimada Mayumi、Yamashita Taro、Sakai Yoshio、Yamashita Tatsuya、Mizukoshi Eishiro、Honda Masao、Kaneko Shuichi、Ota Tsuguhito
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 815-815
- DOI
  10.1038/s41598-020-57784-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11764, KAKENHI-PLANNED-17H06393, KAKENHI-PROJECT-18H02793, KAKENHI-PROJECT-19H04047
[Journal Article] Lactobacillus pentosus strain S-PT84 improves steatohepatitis by maintaining gut permeability2020
- Author(s)
  Sakai Yuriko、Arie Hideyuki、Ni Yinhua、Zhuge Fen、Xu Liang、Chen Guanliang、Nagata Naoto、Suzuki Takuya、Kaneko Shuichi、Ota Tsuguhito、Nagashimada Mayumi
- Journal Title
  
  Journal of Endocrinology
  
  Volume: 247 Issue: 2 Pages: 169-181
- DOI
  10.1530/joe-20-0105
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11764, KAKENHI-PLANNED-17H06393, KAKENHI-PROJECT-19H04052
[Journal Article] DPP-4 Inhibition with Anagliptin Reduces Lipotoxicity-Induced Insulin Resistance and Steatohepatitis in Male Mice2020
- Author(s)
  Sakai Yuriko、Chen Guanliang、Ni Yinhua、Zhuge Fen、Xu Liang、Nagata Naoto、Kaneko Shuichi、Ota Tsuguhito、Nagashimada Mayumi
- Journal Title
  
  Endocrinology
  
  Volume: 161 Issue: 10
- DOI
  10.1210/endocr/bqaa139
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11764, KAKENHI-PLANNED-17H06393
[Journal Article] Fatty acid-driven modifications in T-cell profiles in non-alcoholic fatty liver disease patients.2020
- Author(s)
  T Seike, E Mizukoshi, K Yamada, H Okada, M Kitahara, T Yamashita, K Arai, T Terashima, N Iida, K Fushimi, T Yamashita, Y Sakai, M Honda, K Harada, S Kaneko.
- Journal Title
  
  J Gastroenterol
  
  Volume: - Issue: 7 Pages: 701-711
- DOI
  10.1007/s00535-020-01679-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06393, KAKENHI-PROJECT-18H02793, KAKENHI-PROJECT-17K15934, KAKENHI-PROJECT-19K17455, KAKENHI-PROJECT-19K17485
[Journal Article] Induction of Selenoprotein P mRNA during Hepatitis C Virus Infection Inhibits RIG-I-Mediated Antiviral Immunity.2019
- Author(s)
  Murai K, Honda M, Shirasaki T, Shimakami T, Omura H, Misu H, Kita Y, Takeshita Y, Ishii KA, Takamura T, Urabe T, Shimizu R, Okada H, Yamashita T, Sakai Y, Kaneko S.
- Journal Title
  
  Cell Host Microbe
  
  Volume: 10;25(4) Issue: 4 Pages: 588-601
- DOI
  10.1016/j.chom.2019.02.015
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15933, KAKENHI-PROJECT-18K08507, KAKENHI-PROJECT-19K08975, KAKENHI-PROJECT-18K19560, KAKENHI-PROJECT-19K17427, KAKENHI-PLANNED-17H06393, KAKENHI-PROJECT-17H04199, KAKENHI-PROJECT-18H02793, KAKENHI-PROJECT-16K09739, KAKENHI-PROJECT-16K09740, KAKENHI-PROJECT-17K09413
[Journal Article] Lycopene Alleviates Obesity‐Induced Inflammation and Insulin Resistance by Regulating M1/M2 Status of Macrophages2019
- Author(s)
  Chen Guanliang、Ni Yinhua、Nagata Naoto、Zhuge Fen、Xu Liang、Nagashimada Mayumi、Yamamoto Sayo、Ushida Yusuke、Fuke Nobuo、Suganuma Hiroyuki、Kaneko Shuichi、Ota Tsuguhito
- Journal Title
  
  Molecular Nutrition & Food Research
  
  Volume: 63 Issue: 21 Pages: 1900602-1900602
- DOI
  10.1002/mnfr.201900602
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11764, KAKENHI-PLANNED-17H06393, KAKENHI-PROJECT-19H04047
[Journal Article] Pirfenidone prevents and reverses hepatic insulin resistance and steatohepatitis by polarizing M2 macrophages2019
- Author(s)
  Chen Guanliang、Ni Yinhua、Nagata Naoto、Xu Liang、Zhuge Fen、Nagashimada Mayumi、Kaneko Shuichi、Ota Tsuguhito
- Journal Title
  
  Laboratory Investigation
  
  Volume: - Issue: 9 Pages: 1335-1348
- DOI
  10.1038/s41374-019-0255-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05345, KAKENHI-PROJECT-19K11764, KAKENHI-PLANNED-17H06393, KAKENHI-PROJECT-19H04047
[Journal Article] Adipose tissue‐derived stem cells prevent fibrosis in murine steatohepatitis by suppressing IL‐17‐mediated inflammation2019
- Author(s)
  Yamato Masatoshi、Sakai Yoshio、Mochida Hatsune、Kawaguchi Kazunori、Takamura Masayuki、Usui Soichiro、Seki Akihiro、Mizukoshi Eishiro、Yamashita Taro、Yamashita Tatsuya、Ishida Kousuke、Nasti Alessandro、Tuyen Ho Thuy Bich、Komura Takuya、Yoshida Keiko、Wada Takashi、Honda Masao、Kaneko Shuichi
- Journal Title
  
  Journal of Gastroenterology and Hepatology
  
  Volume: - Issue: 8 Pages: 1432-1440
- DOI
  10.1111/jgh.14647
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06394, KAKENHI-PROJECT-16K09425, KAKENHI-PLANNED-17H06393, KAKENHI-PROJECT-18H02793, KAKENHI-PROJECT-17K09413
[Journal Article] Diabetes impairs the angiogenic capacity of human adipose-derived stem cells by reducing the CD271+ subpopulation in adipose tissue2019
- Author(s)
  Inoue Oto、Usui Soichiro、Takashima Shin-ichiro、Nomura Ayano、Yamaguchi Kosei、Takeda Yusuke、Goten Chiaki、Hamaoka Takuto、Ootsuji Hiroshi、Murai Hisayoshi、Kaneko Shuichi、Takamura Masayuki
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 517 Issue: 2 Pages: 369-375
- DOI
  10.1016/j.bbrc.2019.07.081
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08486, KAKENHI-PLANNED-17H06393
[Journal Article] Lycopene prevents the progression of lipotoxicity-induced nonalcoholic steatohepatitis by decreasing oxidative stress in mice2019
- Author(s)
  Ni Yinhua、Zhuge Fen、Nagashimada Mayumi、Nagata Naoto、Xu Liang、Yamamoto Sayo、Fuke Nobuo、Ushida Yusuke、Suganuma Hiroyuki、Kaneko Shuichi、Ota Tsuguhito
- Journal Title
  
  Free Radical Biology and Medicine
  
  Volume: - Pages: 225-234
- DOI
  10.1016/j.freeradbiomed.2019.11.036
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11764, KAKENHI-PLANNED-17H06393, KAKENHI-PROJECT-19H04047
[Journal Article] Serum aldo-keto reductase family 1 member B10 predicts advanced liver fibrosis and fatal complications of nonalcoholic steatohepatitis.2019
- Author(s)
  M Kanno, K Kawaguchi, M Honda, R Horii, H Takatori, T Shimakami, K Kitamura, K Arai, T Yamashita, Y Sakai, T Yamashita, E Mizukoshi, S Kaneko.
- Journal Title
  
  J Gastroenterol
  
  Volume: - Issue: 6 Pages: 549-557
- DOI
  10.1007/s00535-019-01551-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-18H02793, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06393, KAKENHI-PROJECT-17K09413, KAKENHI-PROJECT-17K09414
[Journal Article] Empagliflozin reverses obesity and insulin resistance through fat browning and alternative macrophage activation in mice fed a high-fat diet2019
- Author(s)
  Xu Liang、Nagata Naoto、Chen Guanliang、Nagashimada Mayumi、Zhuge Fen、Ni Yinhua、Sakai Yuriko、Kaneko Shuichi、Ota Tsuguhito
- Journal Title
  
  BMJ Open Diabetes Research & Care
  
  Volume: 7 Issue: 1 Pages: e000783-e000783
- DOI
  10.1136/bmjdrc-2019-000783
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11764, KAKENHI-PLANNED-17H06393, KAKENHI-PROJECT-19H04047
[Journal Article] Distinct chemotherapy-associated anti-cancer immunity by myeloid cells inhibition in murine pancreatic cancer models.2019
- Author(s)
  Sakai Y, Miyazawa M, Komura T, Yamada T, Nasti A, Yoshida K, Takabatake H, Yamato M, Yamashita T, Yamashita T, Mizukoshi E, Okuzono M, Ho TTB, Kawaguchi K, Wada T, Honda M, Kaneko S.
- Journal Title
  
  Cancer Sci
  
  Volume: 110 Issue: 3 Pages: 903-912
- DOI
  10.1111/cas.13944
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09413, KAKENHI-PLANNED-17H06393, KAKENHI-PROJECT-18H02793
[Journal Article] p62-mediated autophagy affects nutrition-dependent insulin receptor substrate 1 dynamics in 3T3-L1 preadipocytes2019
- Author(s)
  Igawa Hirobumi、Kikuchi Akihiro、Misu Hirofumi、Ishii Kiyo-aki、Kaneko Shuichi、Takamura Toshinari
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: 10 Issue: 1 Pages: 32-42
- DOI
  10.1111/jdi.12866
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09822, KAKENHI-PROJECT-18K08507, KAKENHI-PROJECT-18K19560, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-17H04199
[Journal Article] Circulating Concentrations of Insulin Resistance-Associated Hepatokines, Selenoprotein P and Leukocyte Cell-Derived Chemotaxin 2, during an Oral Glucose Tolerance Test in Humans2019
- Author(s)
  Mohri K, Misu H, Takayama H, Ishii KA, Kikuchi A, Lan F, Enyama Y, Takeshita Y, Saito Y, Kaneko S,Takamura T.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 42 Issue: 3 Pages: 373-378
- DOI
  10.1248/bpb.b18-00549
- NAID
  130007607371
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2019-03-01
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09739, KAKENHI-PROJECT-16K09740, KAKENHI-PROJECT-18K08507, KAKENHI-PROJECT-18K19560, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06393, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-19K08975, KAKENHI-PROJECT-17H04199, KAKENHI-PROJECT-17K09822, KAKENHI-PROJECT-17H03821
[Journal Article] Characteristics of Immune Response to Tumor‐Associated Antigens and Immune Cell Profile in Patients With Hepatocellular Carcinoma.2019
- Author(s)
  Y Inada, E Mizukoshi, T Seike, T Tamai, N Iida, M Kitahara, T Yamashita, K Arai, T Terashima, K Fushimi, T Yamashita, M Honda, S Kaneko.
- Journal Title
  
  Hepatology
  
  Volume: 69 Issue: 2 Pages: 653-665
- DOI
  10.1002/hep.30212
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06393, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-18H02793, KAKENHI-PROJECT-16H04695
[Journal Article] Serum C16:1n7/C16:0 ratio as a diagnostic marker for non-alcoholic steatohepatitis.2019
- Author(s)
  K Yamada, E Mizukoshi, T Seike, R Horii, T Terashima, N Iida, M Kitahara, H Sunagozaka, K Arai, T Yamashita, M Honda, T Takamura, K Harada, S Kaneko.
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: 34 Issue: 10 Pages: 1829-1835
- DOI
  10.1111/jgh.14654
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06393, KAKENHI-PROJECT-17H04058, KAKENHI-PROJECT-18H02793
[Journal Article] Light alcohol consumption has the potential to suppress hepatocellular injury and liver fibrosis in non-alcoholic fatty liver disease.2018
- Author(s)
  K Yamada, E Mizukoshi, T Seike, R Horii, M Kitahara, H Sunagozaka, K Arai, T Yamashita, M Honda, S Kaneko.
- Journal Title
  
  PLoS One
  
  Volume: 13 Issue: 1 Pages: e0191026-e0191026
- DOI
  10.1371/journal.pone.0191026
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-15H04809, KAKENHI-ORGANIZER-17H06391
[Journal Article] A porcine placental extract prevents steatohepatitis by suppressing activation of macrophages and stellate cells in mice.2018
- Author(s)
  L Xu, N Nagata, M Nagashimada, F Zhuge, Y Ni, G Chen, J Kamei, H Ishikawa, Y Komatsu, S Kaneko, T Ota.
- Journal Title
  
  Oncotarget
  
  Volume: 9 Issue: 19 Pages: 15047-15060
- DOI
  10.18632/oncotarget.24587
- NAID
  120006452383
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-15H05345, KAKENHI-PROJECT-16H03035
[Journal Article] Immune response to human telomerase reverse transcriptase-derived helper T cell epitopes in hepatocellular carcinoma patients2018
- Author(s)
  Kumagai Masashi、Mizukoshi Eishiro、Tamai Toshikatsu、Kitahara Masaaki、Yamashita Tatsuya、Arai Kuniaki、Terashima Takeshi、Iida Noriho、Fushimi Kazumi、Kaneko Shuichi
- Journal Title
  
  Liver International
  
  Volume: 印刷中 Issue: 9 Pages: 1635-1645
- DOI
  10.1111/liv.13713
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15934, KAKENHI-PLANNED-17H06393, KAKENHI-PROJECT-26253046
[Journal Article] Effects of metformin and alogliptin on body composition in people with type 2 diabetes.2018
- Author(s)
  Takeshita Y, Kita Y, Kato KI, Kanamori T, Misu H, Kaneko, Takamura T.
- Journal Title
  
  J Diabetes Investig
  
  Volume: Aug Issue: 3 Pages: 29-29
- DOI
  10.1111/jdi.12920
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09739, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-19K08975
[Journal Article] The osteopontin-CD44 axis in hepatic cancer stem cells regulates IFN signaling and HCV replication.2018
- Author(s)
  Shirasaki T, Honda M, Yamashita T, Nio K, Shimakami T, Shimizu R, Nakasyo S, Murai K, Shirasaki N, Okada H, Sakai Y, Sato T, Suzuki T, Yoshioka K, Kaneko S.
- Journal Title
  
  Sci Rep.
  
  Volume: 8 Issue: 1 Pages: 13143-13143
- DOI
  10.1038/s41598-018-31421-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09413, KAKENHI-PROJECT-18K19538, KAKENHI-PLANNED-17H06393, KAKENHI-PROJECT-18H02661, KAKENHI-PROJECT-18H02792, KAKENHI-PROJECT-18H02793, KAKENHI-PROJECT-16K08579, KAKENHI-PROJECT-16K21058, KAKENHI-PROJECT-17K15933, KAKENHI-PROJECT-16H04695
[Journal Article] Serum selenoprotein P, but not selenium, predicts future hyperglycemia in a general Japanese population.2018
- Author(s)
  Oo SM, Misu H, Saito Y, Tanaka M, Kato S, Kita Y, Takayama H, Takeshita Y, Kanamori T, Nagano T, Nakagen M, Urabe T, Matsuyama N, Kaneko S, Takamura T.
- Journal Title
  
  Sci Rep.
  
  Volume: 8 Issue: 1 Pages: 16727-16727
- DOI
  10.1038/s41598-018-35067-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09739, KAKENHI-PROJECT-16K09740, KAKENHI-PROJECT-18K19560, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06393, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-17H04199, KAKENHI-PROJECT-17H03821
[Journal Article] Comparison of Human Selenoprotein P Determinants in Serum between Our Original Methods and Commercially Available Kits2018
- Author(s)
  Saito Yoshiro、Misu Hirofumi、Takayama Hiroaki、Takashima Shin-ichiro、Usui Soichiro、Takamura Masayuki、Kaneko Shuichi、Takamura Toshinari、Noguchi Noriko
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 41 Issue: 5 Pages: 828-832
- DOI
  10.1248/bpb.b18-00046
- NAID
  130006730702
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2018-05-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19560, KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-17H04199, KAKENHI-PROJECT-16K09425, KAKENHI-PROJECT-17H03821
[Journal Article] Optimal management of patients with hepatocellular carcinoma treated with lenvatinib2018
- Author(s)
  Ikeda Masafumi、Kobayashi Masahiro、Tahara Makoto、Kaneko Shuichi
- Journal Title
  
  Expert Opinion on Drug Safety
  
  Volume: 17 Issue: 11 Pages: 1095-1105
- DOI
  10.1080/14740338.2018.1530212
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H04695
[Journal Article] Ribavirin-induced down-regulation of CCAAT/enhancer-binding protein α leads to suppression of lipogenesis2018
- Author(s)
  Satoh Shinya、Onomura Daichi、Ueda Youki、Dansako Hiromichi、Honda Masao、Kaneko Shuichi、Kato Nobuyuki
- Journal Title
  
  Biochemical Journal
  
  Volume: 476 Issue: 1 Pages: 137-149
- DOI
  10.1042/bcj20180680
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07972, KAKENHI-PLANNED-17H06393, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-16H05196, KAKENHI-PROJECT-18K15169
[Journal Article] Peretinoin, an Acyclic Retinoid, Inhibits Hepatitis B Virus Replication by Suppressing Sphingosine Metabolic Pathway In Vitro.2018
- Author(s)
  1.Murai K, Shirasaki T, Honda M, Shimizu R, Shimakami T, Nakasho S, Shirasaki N, Okada H, Sakai Y, Yamashita T, Kaneko S.
- Journal Title
  
  International Journal of Molecular Sciences.
  
  Volume: 19(2) Issue: 2 Pages: 108-108
- DOI
  10.3390/ijms19020108
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15933, KAKENHI-PROJECT-15H04809, KAKENHI-PROJECT-15K08492, KAKENHI-PROJECT-16K21058, KAKENHI-PROJECT-16H04695
[Journal Article] Immune responses against tumor-associated antigen-derived cytotoxic T lymphocyte epitopes in cholangiocarcinoma patients.2018
- Author(s)
  Kida A, Mizukoshi E, Tamai T, Kitahara M, Yamashita T, Arai K, Terashima T, Iida N, Fushimi K, Kaneko S.
- Journal Title
  
  Liver Int
  
  Volume: 38 Issue: 11 Pages: 2040-2050
- DOI
  10.1111/liv.13885
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15934, KAKENHI-PLANNED-17H06393, KAKENHI-PROJECT-18H02793
[Journal Article] Prevention of hepatocellular carcinoma by targeting MYCN-positive liver cancer stem cells with acyclic retinoid2018
- Author(s)
  Qin XY, Suzuki H, Honda M, Okada H, Kaneko S, Inoue I, Ebisui E, Hashimoto K, Carninci P, Kanki K, Tatsukawa H, Ishibashi N, Masaki T, Matsuura T, Kagechika H, Toriguchi K, Hatano E, Shirakami Y, Shiota G, Shimizu M, Moriwaki H, Kojima S
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 115 Issue: 19 Pages: 4969-4974
- DOI
  10.1073/pnas.1802279115
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09035, KAKENHI-PROJECT-16K19378, KAKENHI-PROJECT-18K06976, KAKENHI-PROJECT-18K15833, KAKENHI-PLANNED-17H06393, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-18H02793, KAKENHI-PROJECT-16K09352, KAKENHI-PROJECT-16K09353, KAKENHI-PROJECT-17K15933
[Journal Article] Ursodeoxycholic acid potentiates dipeptidyl peptidase-4 inhibitor sitagliptin by enhancing glucagon-like peptide-1 secretion in patients with type 2 diabetes and chronic liver disease: a pilot randomized controlled and add-on study2018
- Author(s)
  K. R. Shima, T. Ota, K. I. Kato, Y. Takeshita, H. Misu, S. Kaneko and T. Takamura
- Journal Title
  
  BMJ Open Diabetes Res Care
  
  Volume: 6 Issue: 1 Pages: e000469-e000469
- DOI
  10.1136/bmjdrc-2017-000469
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09740, KAKENHI-PROJECT-16K19533, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-17H04199, KAKENHI-PROJECT-16H03035
[Journal Article] Sirt2 facilitates hepatic glucose uptake by deacetylating glucokinase regulatory protein2018
- Author(s)
  Watanabe Hitoshi、Inaba Yuka、Kimura Kumi、Matsumoto Michihiro、Kaneko Shuichi、Kasuga Masato、Inoue Hiroshi
- Journal Title
  
  Nat Commun.
  
  Volume: 9 Issue: 1 Pages: 30-30
- DOI
  10.1038/s41467-017-02537-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K00849, KAKENHI-PUBLICLY-17H05499, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-15H04851, KAKENHI-PROJECT-16J08117, KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-15H05678
[Journal Article] Ribavirin suppresses hepatic lipogenesis through inosine monophosphate dehydrogenase inhibition: Involvement of adenosine monophosphate-activated protein kinase-related kinases and retinoid X receptor α.2017
- Author(s)
  S Satoh, K Mori, D Onomura, Y Ueda, H Dansako, M Honda, S Kaneko, M Ikeda, N Kato.
- Journal Title
  
  Hepatol Commun
  
  Volume: 1 Issue: 6 Pages: 550-563
- DOI
  10.1002/hep4.1065
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06393, KAKENHI-PROJECT-15H04809, KAKENHI-PROJECT-16H05196
[Journal Article] Beneficial Effect of Maintaining Hepatic Reserve during Chemotherapy on the Outcomes of Patients with Hepatocellular Carcinoma.2017
- Author(s)
  Terashima T, Yamashita T, Arai K, Kawaguchi K, Kitamura K, Yamashita T, Sakai Y, Mizukoshi E, Honda M, Kaneko S.
- Journal Title
  
  Liver Cancer
  
  Volume: 6 Issue: 3 Pages: 236-249
- DOI
  10.1159/000472262
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09413, KAKENHI-PROJECT-17K09414, KAKENHI-PROJECT-17K15934, KAKENHI-PROJECT-15H04809, KAKENHI-PROJECT-16H04695
[Journal Article] Glucoraphanin ameliorates obesity and insulin resistance through adipose tissue browning and reduction of metabolic endotoxemia in mice.2017
- Author(s)
  Nagata N, Xu L, Kohno S, Ushida Y, Aoki Y, Umeda R, Fuke N, Zhuge F, Ni Y, Nagashimada M, Takahashi C, Suganuma H, Kaneko S and Ota T.
- Journal Title
  
  Diabetes
  
  Volume: 印刷中 Issue: 5 Pages: 1222-1236
- DOI
  10.2337/db16-0662
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01487, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-15H05345, KAKENHI-PROJECT-26290037, KAKENHI-PROJECT-15K00813, KAKENHI-PROJECT-17K19586, KAKENHI-PROJECT-17K14992, KAKENHI-PUBLICLY-17H05615, KAKENHI-PROJECT-16H03035, KAKENHI-PROJECT-17H03576
[Journal Article] Clinical and pathological significance of autoantibodies to erythropoietin receptor in type 2 diabetic patients with chronic kidney disease2017
- Author(s)
  Hara A, Furuichi K, Koshino A, Yasuda H, Tran T, Iwata Y, Sakai N, Shimizu M, Kaneko S, Nakamura H, Wada T.
- Journal Title
  
  Kidney Int Rep
  
  Volume: 3 Issue: 1 Pages: 133-141
- DOI
  10.1016/j.ekir.2017.08.017
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09608, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-16H05837, KAKENHI-PROJECT-15K09251, KAKENHI-PROJECT-17K09691
[Journal Article] Weight-adjusted lean body mass and calf circumference are protective against obesity-associated insulin resistance and metabolic abnormalities.2017
- Author(s)
  Takamura T, Kita Y, Nakagen M, Sakurai M, Isobe Y, Takeshita Y, Kawai K, Urabe T, Kaneko S.
- Journal Title
  
  Heliyon.
  
  Volume: 3 Issue: 7 Pages: e00347-e00347
- DOI
  10.1016/j.heliyon.2017.e00347
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09739, KAKENHI-PLANNED-17H06393, KAKENHI-PROJECT-17H04199
[Journal Article] Hepatic Transcriptome Profiles of Mice with Diet-Induced Nonalcoholic Steatohepatitis Treated with Astaxanthin and Vitamin E.2017
- Author(s)
  M Kobori, Y Takahashi, M Sakurai, Y Ni, G Chen, M Nagashimada, S Kaneko, T Ota.
- Journal Title
  
  Int J Mol Sci
  
  Volume: 18 Issue: 3 Pages: 593-593
- DOI
  10.3390/ijms18030593
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-16H03035, KAKENHI-PROJECT-15H05345, KAKENHI-PROJECT-15K12698
[Journal Article] Deficiency of the hepatokine selenoprotein P increases responsiveness to exercise in mice through upregulation of reactive oxygen species and AMP-activated protein kinase in muscle.2017
- Author(s)
  H Misu, H Takayama, Y Saito, Y Mita, A Kikuchi, K Ishii, K Chikamoto, T Kanamori, N Tajima, F Lan, Y Takeshita, M Honda, M Tanaka, S Kato, N Matsuyama, Y Yoshioka, Iwayama K, Tokuyama K, Akazawa N, Maeda S, Takekoshi K, Matsugo S, Noguchi N, S Kaneko, T Takamura.
- Journal Title
  
  Nature Med
  
  Volume: 23 Issue: 4 Pages: 508-516
- DOI
  10.1038/nm.4295
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-15H04809, KAKENHI-PROJECT-26461328, KAKENHI-PROJECT-26461329, KAKENHI-PROJECT-16K15426, KAKENHI-PROJECT-16K09739, KAKENHI-PROJECT-16K09740, KAKENHI-PROJECT-25292078, KAKENHI-PROJECT-17H04199
[Journal Article] Sorafenib suppresses extrahepatic metastasis de novo in hepatocellular carcinoma through inhibition of mesenchymal cancer stem cells characterized by the expression of CD90.2017
- Author(s)
  5.Yoshida M, Yamashita T, Okada H, Oishi N, Nio K, Hayashi T, Nomura Y, Hayashi T, Asahina Y, Ohwada M, Sunagozaka H, Takatori H, Colombo F, Porretti L, Honda M, Kaneko S.
- Journal Title
  
  Scientific Reports.
  
  Volume: 12;7(1) Issue: 1 Pages: 11292-11292
- DOI
  10.1038/s41598-017-11848-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15933, KAKENHI-PROJECT-15H04809, KAKENHI-PROJECT-16H04695, KAKENHI-PROJECT-15K08992
[Journal Article] Gene expression profiling of hepatocarcinogenesis in a mouse model of chronic hepatitis B2017
- Author(s)
  Nosaka Takuto、Naito Tatsushi、Hiramatsu Katsushi、Ohtani Masahiro、Nemoto Tomoyuki、Marusawa Hiroyuki、Ma Ning、Hiraku Yusuke、Kawanishi Shosuke、Yamashita Taro、Kaneko Shuichi、Nakamoto Yasunari
- Journal Title
  
  PLoS One.
  
  Volume: 12 Issue: 10 Pages: e0185442-e0185442
- DOI
  10.1371/journal.pone.0185442
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09168, KAKENHI-PROJECT-17K19806, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-15H04784, KAKENHI-PROJECT-16H05255, KAKENHI-PROJECT-16H05829, KAKENHI-PROJECT-17H04654, KAKENHI-PROJECT-15K08787
[Journal Article] Dietary Mung Bean Protein Reduces Hepatic Steatosis, Fibrosis, and Inflammation in Male Mice with Diet-Induced, Nonalcoholic Fatty Liver Disease.2017
- Author(s)
  Watanabe H, Inaba Y, Kimura K, Asahara SI, Kido Y, Matsumoto M, Motoyama T, Tachibana N, Kaneko S, Kohno M, Inoue H*.
- Journal Title
  
  J Nutr.
  
  Volume: 147 Issue: 1 Pages: 52-60
- DOI
  10.3945/jn.116.231662
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01373, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-15H04851, KAKENHI-PROJECT-15H05678, KAKENHI-PROJECT-16J08117, KAKENHI-PROJECT-26282022, KAKENHI-PROJECT-26461382, KAKENHI-PROJECT-16K00849
[Journal Article] Corrigendum to 'Weight-adjusted lean body mass and calf circumference are protective against obesity-associated insulin resistance and metabolic abnormalities'.2017
- Author(s)
  T Takamura, Y Kita, M Nakagen, M Sakurai, Y Isobe, Y Takeshita, K Kawai, T Urabe, S Kaneko.
- Journal Title
  
  Heliyon
  
  Volume: 3 Issue: 7 Pages: e00363-e00363
- DOI
  10.1016/j.heliyon.2017.e00363
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06393, KAKENHI-PROJECT-26253046
[Journal Article] Association Between High-Avidity T-Cell Receptors, Induced by α-Fetoprotein-Derived Peptides, and Anti-Tumor Effects in Patients With Hepatocellular Carcinoma2017
- Author(s)
  Nakagawa H, Mizukoshi E, Kobayashi E, Tamai T, Hamana H, Ozawa T, Kishi H, Kitahara M, Yamashita T, Arai K, Terashima T, Iida N, Fushimi K, Muraguchi A, Kaneko S
- Journal Title
  
  Gastroenterology
  
  Volume: 152 Issue: 6 Pages: 1395-1406
- DOI
  10.1053/j.gastro.2017.02.001
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06499, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-26293237, KAKENHI-PROJECT-16K15425, KAKENHI-PROJECT-15H04980, KAKENHI-PROJECT-15K09522
[Journal Article] The evolving concept of liver cancer stem cells.2017
- Author(s)
  K Nio, T Yamashita, S Kaneko.
- Journal Title
  
  Mol Cancer
  
  Volume: 16 Issue: 1 Pages: 4-4
- DOI
  10.1186/s12943-016-0572-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-26460994
[Journal Article] Eicosapentaenoic acid down-regulates expression of the selenoprotein P gene by inhibiting SREBP-1c protein independently of the AMP-activated protein kinase pathway in H4IIEC3 hepatocytes.2017
- Author(s)
  Tajima-Shirasaki N, Ishii KA, Takayama H, Shirasaki T, Iwama H, Chikamoto K, Saito Y, Iwasaki Y, Teraguchi A, Lan F, Kikuchi A, Takeshita Y, Murao K, Matsugo S, Kaneko S, Misu H, Takamura T.
- Journal Title
  
  J Biol Chem.
  
  Volume: 292 Issue: 26 Pages: 10791-10800
- DOI
  10.1074/jbc.m116.747006
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09739, KAKENHI-PROJECT-16K09740, KAKENHI-PROJECT-16K21058, KAKENHI-PLANNED-17H06393, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-17H04199, KAKENHI-PROJECT-17H03821
[Journal Article] Peretinoin, an acyclic retinoid, suppresses steatohepatitis and tumorigenesis by activating autophagy in mice fed an atherogenic high-fat diet2017
- Author(s)
  Okada H, Takabatake R, Honda M, Takegoshi K, Yamashita T, Nakamura M, Shirasaki T, Sakai Y, Shimakami T, Nagata N, Takamura T, Tanaka T, Kaneko S.
- Journal Title
  
  Oncotarget
  
  Volume: 8 Issue: 25 Pages: 39978-39993
- DOI
  10.18632/oncotarget.18116
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09413, KAKENHI-PROJECT-16K21058, KAKENHI-PROJECT-17K15933, KAKENHI-PLANNED-17H06393, KAKENHI-PROJECT-15H04809
[Journal Article] SGLT2 Inhibition by Empagliflozin Promotes Fat Utilization and Browning and Attenuates Inflammation and Insulin Resistance by Polarizing M2 Macrophages in Diet-induced Obese Mice.2017
- Author(s)
  L Xu, N Nagata, M Nagashimada, F Zhuge, Y Ni, G Chen, E Mayoux, S Kaneko, T Ota.
- Journal Title
  
  EBioMedicine
  
  Volume: 20 Pages: 137-149
- DOI
  10.1016/j.ebiom.2017.05.028
- NAID
  120006452382
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06393, KAKENHI-PROJECT-16H03035
[Journal Article] Branched-chain amino acids prevent hepatic fibrosis and development of hepatocellular carcinoma in a non-alcoholic steatohepatitis mouse model.2017
- Author(s)
  K Takegoshi, M Honda, H Okada, R Takabatake, N Matsuzawa-Nagata, JS Campbell, M Nishikawa, T Shimakami, T Shirasaki, Y Sakai, T Yamashita, T Takamura, T Tanaka, S Kaneko.
- Journal Title
  
  Oncotarget
  
  Volume: 印刷中 Issue: 11 Pages: 18191-18205
- DOI
  10.18632/oncotarget.15304
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-15H04809, KAKENHI-PROJECT-26460995, KAKENHI-PROJECT-16K15426, KAKENHI-PROJECT-16K21058
[Journal Article] The CD45+ fraction in murine adipose tissue derived stromal cells harbors immune-inhibitory inflammatory cells.2017
- Author(s)
  Nasti A, Sakai Y, Seki A, Buffa GB, Komura T, Mochida H, Yamato M, Yoshida K, Ho TTB, Takamura M, Usui S, Wada T, Honda M, Kaneko S.
- Journal Title
  
  Eur J Immunol.
  
  Volume: 47 Issue: 12 Pages: 2163-2174
- DOI
  10.1002/eji.201646835
- NAID
  120006454989
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09425, KAKENHI-PROJECT-17K09413, KAKENHI-PLANNED-17H06393, KAKENHI-PROJECT-15H04809
[Journal Article] Reply to the Letter to the Editor by Li et al.: Bioinformatics Analysis in Mice with Diet-Induced Nonalcoholic Steatohepatitis Treated with Astaxanthin and Vitamin E.2017
- Author(s)
  M Kobori, Y Takahashi, M Sakurai, Y Ni, G Chen, M Nagashimada, S Kaneko, T Ota.
- Journal Title
  
  Int J Mol Sci
  
  Volume: 18 Issue: 5 Pages: 994-994
- DOI
  10.3390/ijms18050994
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06393
[Journal Article] Localizatoin of xenobiotic transporter OCTN1/SLC22A4 in hepatic stellate cells and its protective role in liver fibrosis.2016
- Author(s)
  Tang Y, Masuo Y, Sakai Y, Wakayama T, Sugiura T, Harada R, Futatsugi A, Komura T, Nakamichi N, Sekiguchi H, Sutoh K, Usumi K, Iseki S, Kaneko S, Kato Y.
- Journal Title
  
  J Pharm Sci
  
  Volume: 印刷中 Issue: 5 Pages: 1779-89
- DOI
  10.1016/j.xphs.2016.02.023
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04664, KAKENHI-PROJECT-25460092, KAKENHI-PROJECT-26860099, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-16K08266
[Journal Article] DPP-4 inhibition by linagliptin attenuates obesity-related inflammation and insulin resistance by regulating M1/M2 macrophage polarization.2016
- Author(s)
  F Zhuge, Y Ni, M Nagashimada, N Nagata, L Xu, N Mukaida, S Kaneko, T Ota.
- Journal Title
  
  Diabetes
  
  Volume: 65 Issue: 10 Pages: 2966-2679
- DOI
  10.2337/db16-0317
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-16H03035, KAKENHI-PROJECT-15H05345, KAKENHI-PROJECT-15K12698, KAKENHI-PROJECT-16K18700
[Journal Article] Rapid response of the steatosis-sensing hepatokine LECT2 during diet-induced weight cycling in mice.2016
- Author(s)
  K Chikamoto, H Misu, H Takayama, A Kikuchi, KA Ishii, F Lan, N Takata, N Tajima-Shirasaki, Y Takeshita, H Tsugane, S Kaneko, S Matsugo, T Takamura.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 478 Issue: 3 Pages: 1310-1316
- DOI
  10.1016/j.bbrc.2016.08.117
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-26461328, KAKENHI-PROJECT-26461329, KAKENHI-PROJECT-26461377, KAKENHI-PROJECT-16K09740
[Journal Article] Response to Importance of confounding factors in assessing fatty acid compositions in patients with non-alcoholic steatohepatitis2015
- Author(s)
  Yamada K, Mizukoshi E, Sunagozaka H, Arai K, Yamashita T, Takeshita Y, Misu H, Takamura T, Kitamura S, Zen Y, Nakanuma Y, Honda M, Kaneko S
- Journal Title
  
  Liver Int
  
  Volume: 35 Issue: 6 Pages: 1773-1773
- DOI
  10.1111/liv.12755
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461329, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-15H04809, KAKENHI-PROJECT-26670378
[Journal Article] Relationship between Serum Uric Acid Levels and Chronic Kidney Disease in a Japanese Cohort with Normal or Mildly Reduced Kidney Function.2015
- Author(s)
  Toyama T, Furuichi K, Shimizu M, Hara A, Iwata Y, Sakai N, Perkovic V, Kobayashi M, Mano T, Kaneko S, Wada T.
- Journal Title
  
  PLoS One.
  
  Volume: 10 Issue: 9 Pages: e0137449-e0137449
- DOI
  10.1371/journal.pone.0137449
- NAID
  120005680030
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09251, KAKENHI-PROJECT-26461218, KAKENHI-PROJECT-26870218, KAKENHI-PROJECT-26253046
[Journal Article] Liver steatosis is associated with insulin resistance in skeletal muscle rather than in the liver in Japanese patients with non-alcoholic fatty liver disease.2015
- Author(s)
  Kato K, Takeshita Y, Misu H, Zen Y, Kaneko S, Takamura T.
- Journal Title
  
  J Diabetes Investig.
  
  Volume: 6 Issue: 2 Pages: 158-163
- DOI
  10.1111/jdi.12271
- NAID
  120005593987
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461334, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-26461329, KAKENHI-PROJECT-15K08345
[Journal Article] Gadd34 regulates liver regeneration in hepatic steatosis.2015
- Author(s)
  Inaba Y, Furutani T, Kimura K, Watanabe H, Haga S, Kido Y, Yamamoto Y, Harada K, Kaneko S, Oyadomari S, Ozaki M, Kasuga M, Inoue H.
- Journal Title
  
  Hepatology
  
  Volume: 61(4) Issue: 4 Pages: 1343-1356
- DOI
  10.1002/hep.27619
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24590375, KAKENHI-PROJECT-24591348, KAKENHI-PUBLICLY-25126709, KAKENHI-PUBLICLY-25126729, KAKENHI-PROJECT-25861179, KAKENHI-PUBLICLY-26116729, KAKENHI-PROJECT-26282022, KAKENHI-PROJECT-26670599, KAKENHI-PROJECT-26860705, KAKENHI-PROJECT-26460416, KAKENHI-PUBLICLY-15H01373, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-15H05678, KAKENHI-PROJECT-25461335
[Journal Article] Sitagliptin versus mitiglinide switched from mealtime dosing of a rapid-acting insulin analog in patients with type 2 diabetes: a randomized, parallel-group study.2015
- Author(s)
  Y Takeshita, T Takamura, Y Kita, A Takazakura, K Kato, Y Isobe, S Kaneko.
- Journal Title
  
  BMJ Open Diabetes Res Care
  
  Volume: 3 Issue: 1 Pages: e000122-e000122
- DOI
  10.1136/bmjdrc-2015-000122
- NAID
  120005774893
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26253046
[Journal Article] Astaxanthin prevents and reverses diet-induced insulin resistance and steatohepatitis in mice: A comparison with vitamin E2015
- Author(s)
  Ni Y, Nagashimada M, Zhuge F, Zhan L, Nagata N, Tsutsui A, Nakanuma Y, Kaneko S, Ota T
- Journal Title
  
  Sci Rep
  
  Volume: 5 Issue: 1 Pages: 17192-17192
- DOI
  10.1038/srep17192
- NAID
  120005682635
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12698, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-15H05345, KAKENHI-PROJECT-25282017
[Journal Article] Small tRNA-derived RNAs are increased and more abundant than microRNAs in chronic hepatitis B and C.2015
- Author(s)
  Selitsky SR, Baran-Gale J, Honda M, Yamane D, Masaki T, Fannin EE, Guerra B, Shirasaki T, Shimakami T, Kaneko S, Lanford RE, Lemon SM, Sethupathy P.
- Journal Title
  
  Sci Rep.
  
  Volume: 5 Issue: 1 Pages: 7675-7675
- DOI
  10.1038/srep07675
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390187, KAKENHI-PROJECT-24790687, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-15H04809, KAKENHI-PROJECT-26670378
[Journal Article] Renoprotective effects of atorvastatin compared with pravastatin on progression of early diabetic nephropathy2015
- Author(s)
  Takazakura A, Sakurai M, Bando Y, Misu H, Takeshita Y, Kita Y, Shimizu A, Hayakawa T, Kato K, Kaneko S, Takamura T
- Journal Title
  
  J Diabetes Investig
  
  Volume: 6 Issue: 3 Pages: 346-353
- DOI
  10.1111/jdi.12296
- NAID
  120005819637
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461329, KAKENHI-PROJECT-26253046
[Journal Article] Serum DHCR24 Auto-antibody as a new Biomarker for Progression of Hepatitis C.2015
- Author(s)
  Ezzikouri S, Kimura K, Sunagozaka H, Kaneko S, Inoue K, Nishimura T, Hishima T, Kohara M, Tsukiyama-Kohara K.
- Journal Title
  
  EBioMedicine
  
  Volume: Apr 13;2(6) Issue: 6 Pages: 604-12
- DOI
  10.1016/j.ebiom.2015.04.007
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09037, KAKENHI-PROJECT-15K15146, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-24390117
[Journal Article] Characteristics of hepatic fatty acid compositions in patients with nonalcoholic steatohepatitis.2015
- Author(s)
  Yamada K, Mizukoshi E, Sunagozaka H, Arai K, Yamashita T, Takeshita Y, Misu H, Takamura T, Kitamura S, Zen Y, Nakanuma Y, Honda M, Kaneko S.
- Journal Title
  
  Liver Int.
  
  Volume: 35(2) Issue: 2 Pages: 582-90
- DOI
  10.1111/liv.12685
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390187, KAKENHI-PROJECT-25461334, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-26461329, KAKENHI-PROJECT-15H04809, KAKENHI-PROJECT-26670378
[Journal Article] Immunological features of T cells induced by human telomerase reverse transcriptase-derived peptides in patients with hepatocellular carcinoma.2015
- Author(s)
  E Mizukoshi, H Nakagawa, M Kitahara, T Yamashita, K Arai, H Sunagozaka, K Fushimi, E Kobayashi, H Kishi, A Muraguchi, S Kaneko.
- Journal Title
  
  Cancer Lett
  
  Volume: 364 Issue: 2 Pages: 98-105
- DOI
  10.1016/j.canlet.2015.04.031
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-15H04308, KAKENHI-PROJECT-15H04980, KAKENHI-PROJECT-25460984, KAKENHI-PROJECT-25670463, KAKENHI-PROJECT-26293237
[Journal Article] Phase I trial of multidrug resistance-associated protein 3-derived peptide in patients with hepatocellular carcinoma.2015
- Author(s)
  E Mizukoshi, H Nakagawa, M Kitahara, T Yamashita, K Arai, H Sunagozaka, N Iida, K Fushimi, S Kaneko.
- Journal Title
  
  Cancer Lett
  
  Volume: 369 Issue: 1 Pages: 242-249
- DOI
  10.1016/j.canlet.2015.08.020
- NAID
  120005682640
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-25460984
[Journal Article] Vildagliptin vs liraglutide as a second-line therapy switched from sitagliptin-based regimens in patients with type 2 diabetes: A randomized, parallel-group study.2015
- Author(s)
  Takeshita Y, Takamura T, Kita Y, Otoda T, Kato K, Wakakuri H, Yamada M, Misu H, Matsushima Y, Kaneko S
- Journal Title
  
  J Diabetes Investig
  
  Volume: 6 Issue: 2 Pages: 192-200
- DOI
  10.1111/jdi.12269
- NAID
  120005774894
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461334, KAKENHI-PROJECT-26461329, KAKENHI-PROJECT-26253046
[Journal Article] Defeating EpCAM(+) liver cancer stem cells by targeting chromatin remodeling enzyme CHD4 in human hepatocellular carcinoma.2015
- Author(s)
  Nio K, Yamashita T, Okada H, Kondo M, Hayashi T, Hara Y, Nomura Y, Zeng SS, Yoshida M, Hayashi T, Sunagozaka H, Oishi N, Honda M, Kaneko S
- Journal Title
  
  J. Hepatology
  
  Volume: 5 Issue: 5 Pages: 1164-72
- DOI
  10.1016/j.jhep.2015.06.009
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08992, KAKENHI-PROJECT-26460994, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-15H04809, KAKENHI-PROJECT-26670378, KAKENHI-PROJECT-25293171
[Journal Article] Bending of a vertical cannula without alarm during insulin pump therapy as a cause of unexpected hyperglycemia: A Japanese issue?2015
- Author(s)
  Kuroda K, Takeshita Y, Kaneko S, Takamura T
- Journal Title
  
  J Diabetes Investig
  
  Volume: 6 Issue: 6 Pages: 739-740
- DOI
  10.1111/jdi.12357
- NAID
  120005689372
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461329, KAKENHI-PROJECT-26253046
[Journal Article] Hepatocellular Carcinoma with β-Catenin Mutation: Imaging and Pathologic Characteristics.2015
- Author(s)
  Kitao A, Matsui O, Yoneda N, Kozaka K, Kobayashi S, Sanada J, Koda W, Minami T, Inoue D, Yoshida K, Yamashita T, Yamashita T, Kaneko S, Takamura H, Ohta T, Ikeda H, Nakanuma Y, Kita R, Gabata T.
- Journal Title
  
  Radiology.
  
  Volume: 275 Issue: 3 Pages: 708-717
- DOI
  10.1148/radiol.14141315
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461819, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-25461805, KAKENHI-PROJECT-25461873, KAKENHI-PROJECT-26860986
[Journal Article] Inhibition of microRNA-214 ameliorates hepatic fibrosis and tumor incidence in platelet-derived growth factor C transgenic mice.2015
- Author(s)
  H Okada, M Honda, JS Campbell, K Takegoshi, Y Sakai, T Yamashita, T Shirasaki, R Takabatake, M Nakamura, T Tanaka, S Kaneko.
- Journal Title
  
  Cancer Sci
  
  Volume: 106 Issue: 9 Pages: 1143-1152
- DOI
  10.1111/cas.12730
- NAID
  120005830608
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-15H04809, KAKENHI-PROJECT-26670378
[Journal Article] The effects of ezetimibe on non-alcoholic fatty liver disease and glucose metabolism : a randomised controlled trial2014
- Author(s)
  Y Takeshita, T Takamura, M Honda, Y Kita, Y Zen, KI Kato, H Misu, T Ota, M Nakamura, K Yamada, H Sunagozaka, K Arai, T Yamashita, E Mizukoshi, S Kaneko
- Journal Title
  
  Diabetologia
  
  Volume: 57(5) Issue: 5 Pages: 878-90
- DOI
  10.1007/s00125-013-3149-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23249042, KAKENHI-PROJECT-23701098, KAKENHI-PROJECT-24390187, KAKENHI-PROJECT-25282017, KAKENHI-PROJECT-25461334, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-26461329, KAKENHI-PROJECT-26670378
[Journal Article] LECT2 functions as a hepatokine that links obesity to skeletal muscle insulin resistance2014
- Author(s)
  Fei Lan, H Misu, K Chikamoto, H Takayam, A Kikuchi, K Mohri, N Takata, H Hayashi, N Matsuzawa-Nagata, Y Takeshita, H Noda, Y Matsumoto, T Ota, T Nagano, M Nakagen, K Miyamoto, K Takatsuki, T Seo, K Iwayama, K Tokuyama, S Matsugo, H Tang, Y Saito, S Yamagoe, S Kaneko, T Takamura
- Journal Title
  
  Diabete
  
  Volume: 63 Issue: 5 Pages: 1649-1664
- DOI
  10.2337/db13-0728
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-14J03079, KAKENHI-PROJECT-23590275, KAKENHI-PROJECT-23591301, KAKENHI-PROJECT-25282017, KAKENHI-PROJECT-25292078, KAKENHI-PROJECT-25461334, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-26461329, KAKENHI-PROJECT-26670229
[Journal Article] Metformin Suppresses Expression of the Selenoprotein P gene via an AMPK-FoxO3a Pathway in H4IIEC3 Hepatocytes2014
- Author(s)
  H Takayama, H Misu, H Iwama, K Chikamoto, Y Saito, K Murao, A Teraguchi, F Lan, A Kikuchi, R Saito, N Tajima, T Shirasaki, S Matsugo, KI Miyamoto, S Kaneko, T Takamura
- Journal Title
  
  J Biol Chem
  
  Volume: 289(1) Issue: 1 Pages: 335-45
- DOI
  10.1074/jbc.m113.479386
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249042, KAKENHI-PROJECT-23591301, KAKENHI-PROJECT-24591352, KAKENHI-PROJECT-25461334, KAKENHI-PROJECT-26461329
[Journal Article] LECT2 functions as a hepatokine that links obesity to skeletal muscle insulin resistance2014
- Author(s)
  F Lan, H Misu, K Chikamoto, H Takayama, A Kikuchi, K Mohri, N Takata, H Hayashi, N Matsuzawa-Nagata, Y Takeshita, H Noda, Y Matsumoto, T Ota, T Nagano, M Nakagen, KI Miyamoto, K Takatsuki, T Seo, K Iwayama, K Tokuyama, S Matsugo, H Tang, Y Saito, S Yamagoe, S Kaneko, T Takamura
- Journal Title
  
  Diabetes
  
  Volume: (in press)
- NAID
  120005440333
- Data Source
  KAKENHI-PROJECT-23249042
[Journal Article] Selenoprotein P as a diabetes-associated hepatokine that impairs angiogenesis by inducing VEGF resistance in vascular endothelial cells.2014
- Author(s)
  Ishikura K, Misu H, Kumazaki M, Takayama H, Matsuzawa-Nagata N, Tajima N, Chikamoto K, Lan F, Ando H, Ota T, Sakurai M, Takeshita Y, Kato K, Fujimura A, Miyamoto K, Saito Y, Kameo S, Okamoto Y, Takuwa Y, Takahashi K, Kidoya H, Takakura N, Kaneko S, Takamura T
- Journal Title
  
  Diabetologia
  
  Volume: 57 Issue: 9 Pages: 1968-1976
- DOI
  10.1007/s00125-014-3306-9
- NAID
  120005463349
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22112005, KAKENHI-PROJECT-24390051, KAKENHI-PUBLICLY-25116711, KAKENHI-PUBLICLY-25122710, KAKENHI-PROJECT-25282017, KAKENHI-PROJECT-25292078, KAKENHI-PROJECT-25461334, KAKENHI-PROJECT-25670162, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-26461329
[Journal Article] Hepatic interferon-stimulated genes are differentially regulated in the liver of chronic hepatitis C patients with different interleukin 28B genotypes2014
- Author(s)
  M Honda, T Shirasaki, T Shimakami, A Sakai, R Horii, K Arai, T Yamashita, Y Sakai, T Yamashita, H Okada, K Murai, M Nakamura, E Mizukoshi, S Kaneko
- Journal Title
  
  Hepatology
  
  Volume: 59(3) Issue: 3 Pages: 828-38
- DOI
  10.1002/hep.26788
- NAID
  120005447749
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23249042, KAKENHI-PROJECT-24390187, KAKENHI-PROJECT-26670378
[Journal Article] Ectopic fat accumulation and distant organ-specific insulin resistance in Japanese people with nonalcoholic Fatty liver disease2014
- Author(s)
  K Kato, T Takamura, Y Takeshita, Y Ryu, H Misu, T Ota, K Tokuyama, S Nagasaka, M Matsuhisa, O Matsui, S Kaneko
- Journal Title
  
  PLoS One
  
  Volume: 9(3) Issue: 3 Pages: e92170-e92170
- DOI
  10.1371/journal.pone.0092170
- NAID
  120005440398
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23249042, KAKENHI-PROJECT-23591301, KAKENHI-PROJECT-25282017, KAKENHI-PROJECT-25461334, KAKENHI-PROJECT-26461329
[Journal Article] Dosing time-dependent effect of raloxifene on plasma plasminogen activator inhibitor-1 concentrations in post-menopausal women with osteoporosis2013
- Author(s)
  H Ando, T Otoda, H Ookami, Y Nagai, A Inano, T Takamura, K Ushijima, K Hosohata, E Matsushita, T Saito, S Kaneko, A Fujimura
- Journal Title
  
  Clin Exp Pharmacol Physiol
  
  Volume: 40(3) Issue: 3 Pages: 227-32
- DOI
  10.1111/1440-1681.12055
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249042, KAKENHI-PROJECT-23591301, KAKENHI-PROJECT-24790535
[Journal Article] A new cloning and expression system yields and validates TCRs from blood lymphocytes of patients with cancer within 10 days.2013
- Author(s)
  Kobayashi E., et al
- Journal Title
  
  Nature Medicne
  
  Volume: 19 Issue: 11 Pages: 1542-1546
- DOI
  10.1038/nm.3358
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11F01415, KAKENHI-PROJECT-23390264, KAKENHI-PROJECT-24650630, KAKENHI-PROJECT-24791019, KAKENHI-PUBLICLY-25133703, KAKENHI-PROJECT-25460984, KAKENHI-PROJECT-25670463
[Journal Article] Discrete nature of EpCAM(+) and CD90(+) cancer stem cells in human hepatocellular carcinoma.2013
- Author(s)
  Yamashita T, Nakamoto Y, et al.
- Journal Title
  
  Hepatology
  
  Volume: 57 Issue: 4 Pages: 1484-1497
- DOI
  10.1002/hep.26168
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390149, KAKENHI-PROJECT-22590723, KAKENHI-PROJECT-23249042, KAKENHI-PROJECT-23590967, KAKENHI-PROJECT-23659396, KAKENHI-PROJECT-24390187, KAKENHI-PROJECT-24701024, KAKENHI-PROJECT-25293171
[Journal Article] Proteasome dysfunction mediates obesity-induced endoplasmic reticulum stress and insulin resistance in the liver2013
- Author(s)
  T Otoda, T Takamura, H Misu, T Ota, S Murata, H Hayashi, H Takayama, A Kikuchi, T Kanamori, KR Shima, F Lan, T Takeda, S Kurita, K Ishikura, Y Kita, K Iwayama, KI Kato, M Uno, Y Takeshita, M Yamamoto, K Tokuyama, S Iseki, K Tanaka, S Kaneko
- Journal Title
  
  Diabetes
  
  Volume: 62(3) Issue: 3 Pages: 811-24
- DOI
  10.2337/db11-1652
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249042, KAKENHI-PROJECT-23591301, KAKENHI-PROJECT-23791022, KAKENHI-PROJECT-25282017
[Journal Article] Adipose tissue-derived stem cells as a regenerative therapy for a mouse steatohepatitis-induced cirrhosis model2013
- Author(s)
  A Seki, S Y akai, T Komura, A Nasti, K Yoshida, M Higashimoto, M Honda, S Usui, M Takamura, T Takamura, T Ochiya, K Furuichi, T Wada, S Kaneko
- Journal Title
  
  Hepatology
  
  Volume: 58(3) Issue: 3 Pages: 1133-42
- DOI
  10.1002/hep.26470
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249042, KAKENHI-PROJECT-23590968, KAKENHI-PROJECT-24390187, KAKENHI-PROJECT-24406028, KAKENHI-PROJECT-24591092, KAKENHI-PROJECT-25670269
[Journal Article] CCR5 plays a critical role in obesity-induced adipose tissue inflammation and insulin resistance by regulating both macrophage recruitment and M1/M2 status2012
- Author(s)
  Kitade H, Sawamoto K, Nagashimada M, Inoue H, Yamamoto Y, Sai Y, Takamura T, Yamamoto H, Miyamoto K, Ginsberg HN, Mukaida N, Kaneko S, Ota T
- Journal Title
  
  Diabetes IN PRESS
  
  Volume: 61(7) Issue: 7 Pages: 1680-90
- DOI
  10.2337/db11-1506
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790854, KAKENHI-PROJECT-23249042, KAKENHI-PROJECT-23591301, KAKENHI-PROJECT-23659430
[Journal Article] Inverse correlation between serum levels of selenoprotein P and adiponectin in patients with type 2 diabetes2012
- Author(s)
  H Misu, K Ishikura, S Kurita, Y Takeshita, T Ota, Y Saito, K Takahashi, S Kaneko, T Takamura
- Journal Title
  
  PLoS One
  
  Volume: 7(4) Issue: 4 Pages: e34952-e34952
- DOI
  10.1371/journal.pone.0034952
- NAID
  120004140847
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249042, KAKENHI-PROJECT-23591301, KAKENHI-PROJECT-23791022
[Journal Article] Pharmacokinetics and pharmacodynamics of insulin aspart in patients with Type 2 diabetes : Assessment using a meal tolerance test under clinical conditions2012
- Author(s)
  H Ando, S Kurita, A Shimizu, K Kato, K Ishikura, K Taji, M Uno, Y Takeshita, H Misu, A Fujimura, S Kaneko, T Takamura
- Journal Title
  
  Clin Exp Pharmacol Physiol
  
  Volume: 39(6) Issue: 6 Pages: 528-34
- DOI
  10.1111/j.1440-1681.2012.05708.x
- NAID
  120004442389
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249042, KAKENHI-PROJECT-23791022
[Journal Article] Metformin prevents and reverses inflammation in a non-diabetic mouse model of nonalcoholic steatohepatitis2012
- Author(s)
  Y Kita, T Takamura, H Misu, T Ota, S Kurita, Y Takeshita, M Uno, N Matsuzawa-Nagata, K Kato, H Ando, A Fujimura, K Hayashi, T Kimura, Y Ni, T Otoda, K Miyamoto, Y Zen, Y Nakanuma, S Kaneko
- Journal Title
  
  PLoS One
  
  Volume: 7(9) Issue: 9 Pages: e43056-e43056
- DOI
  10.1371/journal.pone.0043056
- NAID
  120004966626
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249042, KAKENHI-PROJECT-23591301, KAKENHI-PROJECT-23791022
[Journal Article] Beneficial effect of branched-chain amino acid supplementation on glycemic control in chronic hepatitis C patients with insulin resistance : Implications for type 2 diabetes. Metabolism2012
- Author(s)
  Honda M, (他12名, 12番目)
- Journal Title
  
  Epub ahead of print
  
  Volume: (Epub ahead of print) Issue: 10 Pages: 1388-94
- DOI
  10.1016/j.metabol.2012.03.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390227, KAKENHI-PROJECT-23249042, KAKENHI-PROJECT-23590968, KAKENHI-PROJECT-23591301, KAKENHI-PROJECT-23791022, KAKENHI-PROJECT-24390187
[Journal Article] Endoplasmic reticulum stress inhibits STAT3-dependent suppression of hepatic gluconeogenesis via dephosphorylation and deacetylation2012
- Author(s)
  Kimura K, Yamada T, Matsumoto M, Kasuga M, Inoue H., 他9名
- Journal Title
  
  Diabetes
  
  Volume: 61 Issue: 1 Pages: 61-73
- DOI
  10.2337/db10-1684
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591155, KAKENHI-PROJECT-22790861, KAKENHI-PUBLICLY-23126509, KAKENHI-PROJECT-23249042, KAKENHI-PROJECT-23300274, KAKENHI-PUBLICLY-24116526
[Journal Article] Fatty liver as a consequence and cause of insulin resistance : Lessons from type 2 diabetic liver2012
- Author(s)
  T Takamura, H Misu, T Ota, S Kaneko
- Journal Title
  
  Endocr J
  
  Volume: 59(9) Pages: 745-63
- NAID
  10031123118
- Data Source
  KAKENHI-PROJECT-23249042
[Journal Article] Dietary glycemic index and risk of type 2 diabetes in middle-aged Japanese men2012
- Author(s)
  M Sakurai, K Nakamura, K Miura, T Takamura, K Yoshita, Y Morikawa, M Ishizaki, T Kido, Y Naruse, Y Suwazono, S Kaneko, S Sasaki, H Nakagawa
- Journal Title
  
  Metabolism
  
  Volume: 61(1) Issue: 12 Pages: 47-55
- DOI
  10.1016/j.jada.2010.09.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249042
[Journal Article] Efficacy and safety of double filtration plasmapheresis in combination with interferon therapy for chronic hepatitis C.2010
- Author(s)
  S Kaneko
- Journal Title
  
  Hepatol Res
  
  Volume: 40 Pages: 1072-1081
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Enhancement of tumor-specific T cell responses by transcatheter arterial embolization with dendritic cell infusion for hepatocellular carcinoma.2010
- Author(s)
  S Kaneko
- Journal Title
  
  Int J Cancer 126(9)
  
  Pages: 2164-2174
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Hepatocellular Carcinoma : Signal Intensity at Gadoxetic Acid-enhanced MR Imaging-Correlation with Molecular Transporters and Histopathologic Features.2010
- Author(s)
  A Kitao, Y Zen, O Matsui, T Gabata, S Kobayashi, W Koda, K Kozaka, N Yoneda, T Yamashita, S Kaneko, Y Nakanuma.
- Journal Title
  
  Radiology 256(3)
  
  Pages: 817-826
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Hokuriku Liver Study Group. Hepatic ISG expression is associated with genetic variation in IL28B and the outcome of IFN therapy for chronic hepatitis C.2010
- Author(s)
  M Honda, A Sakai, T Yamashita, Y Nakamoto, E Mizukoshi, Y Sakai, T Yamashita, M Nakamura, T Shirasaki, K Horimoto, Y Tanaka, K Tokunaga, M Mizokami, S Kaneko
- Journal Title
  
  Gastroenterology 139(2)
  
  Pages: 499-509
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Differential interferon signaling in liver lobule and portal area cells under treatment for chronic hepatitis2010
- Author(s)
  M Honda, M Nakamura, M Tateno, A Sakai, T Shimakami, T Shirasaki, T Yamashita, K Arai, T Yamashita, Y Sakai, S Kaneko.
- Journal Title
  
  C.J Hepatol 53(5)
  
  Pages: 817-826
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] The histological course of nonalcoholic fatty liver disease in Japanese patients : Tight glycemic control, rather than weight reduction, ameliorates liver fibrosis.2010
- Author(s)
  E Hamaguchi, T Takamura, M Sakurai, E Mizukoshi, Y Zen, Y Takeshita, S Kurita, K Arai, T Yamashita, M Sasaki, Y Nakanuma, S Kaneko.
- Journal Title
  
  Diabetes Care 33(2)
  
  Pages: 284-286
- NAID
  120001938902
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] CD14+monocytes are vulnerable and functionally impaired under ER stress in patients with type 2 diabetes.2010
- Author(s)
  T Komura, Y Sakai, M Honda, T Takamura, K Matsushima, S Kaneko.
- Journal Title
  
  Diabetes 59(3)
  
  Pages: 634-643
- NAID
  120002104558
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Oncostatin m renders epithelial cell adhesion molecule-positive liver cancer stem cells sensitive to 5-Fluorouracil by inducing hepatocytic differentiation.2010
- Author(s)
  T Yamashita, M Honda, K Nio, Y Nakamoto, T Yamashita, H Takamura, T Tani, Y Zen, S Kaneko.
- Journal Title
  
  Cancer Res 70(11)
  
  Pages: 4687-4697
- NAID
  120002220837
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Comprehensive gene expression analysis of 5'-end of mRNA identified novel intronic transcripts associated with hepatocellular carcinoma.2010
- Author(s)
  Y Hodo, SI Hashimoto, M Honda, T Yamashita, Y Suzuki, S Sugano, S Kaneko, K Matsushima.
- Journal Title
  
  Genomics 95(4)
  
  Pages: 217-223
- NAID
  120002086414
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] A liver-derived secretory protein, selenoprotein P, causes insulin resistance.2010
- Author(s)
  H Misu, T Takamura, H Takayama, H Hayashi, N Matsuzawa-Nagata, S Kurita, K Ishikura, H Ando, Y Takeshita, T Ota, M Sakurai, T Yamashita, E Mizukoshi, T Yamashita, M Honda, K Miyamoto, T Kubota, N Kubota, T Kadowaki, HJ Kim, IK Lee, Y Minokoshi, Y Saito, K Takahashi, Y Yamada, N Takakura, S Kaneko.
- Journal Title
  
  Cell Metab 12(5)
  
  Pages: 483-495
- NAID
  120002661942
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Altered hepatic gene expression profiles associated with myocardial ischemia.2010
- Author(s)
  H Ootsuji, M Honda, S Kaneko, S Usui, M Okajima, H Okada, Y Sakai, T Takamura, K Horimoto, M Takamura.
- Journal Title
  
  Circ Cardiovasc Genet 3(1)
  
  Pages: 68-77
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Antitumor Effect after Radiofrequency Ablation of Murine Hepatoma Is Augmented by an Active Variant of CC Chemokine Ligand 3/Macrophage Inflammatory Protein-1α.2010
- Author(s)
  S Kaneko
- Journal Title
  
  Cancer Res 70(16)
  
  Pages: 6556-6565
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Hokuriku Liver Study Group. Differential gene expression profiling in blood from patients with digestive system cancers.2010
- Author(s)
  M Honda, Y Sakai, T Yamashita, T Yamashita, A Sakai, E Mizukoshi, Y Nakamoto, I Tatsumi, Y Miyazaki, H Tanno, S Kaneko
- Journal Title
  
  Biochem Biophys Res Commun 400(1)
  
  Pages: 7-15
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Middle-aged Japanese women are resistant to obesity-related metabolic abnormalities.2009
- Author(s)
  M Sakurai, T Takamura, K Miura, S Kaneko, H Nakagawa.
- Journal Title
  
  Metabolism 58(4)
  
  Pages: 456-459
- NAID
  120001249808
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Palmitate Induces Insulin Resistance in H4IIEC3 Hepatocytes through Reactive Oxygen Species Produced by Mitochondria.2009
- Author(s)
  S Nakamura, T Takamura, N Matsuzawa-Nagata, H Takayama, H Misu, H Noda, S Nabemoto, S Kurita, T Ota, H Ando, K Miyamoto, S Kaneko.
- Journal Title
  
  J Biol Chem 284(22)
  
  Pages: 14809-14818
- NAID
  120002829203
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Clock gene expression in peripheral leucocytes of patients with type 2 diabetes.2009
- Author(s)
  H Ando, T Takamura, N Matsuzawa-Nagata, KR Shima, T Eto, H Misu, M Shiramoto, T Tsuru, S Irie, A Fujimura, S Kaneko.
- Journal Title
  
  Diabetologia 52(2)
  
  Pages: 329-335
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] The hepatic circadian clock is preserved in a lipid-induced mouse model of non-alcoholic steatohepatitis.2009
- Author(s)
  H Ando, T Takamura, N Matsuzawa-Nagata, KR Shima, S Nakamura, M Kumazaki, S Kurita, H Misu, N Togawa, T Fukushima, A Fujimura, S Kaneko.
- Journal Title
  
  Biochem Biophys Res Commun 380(3)
  
  Pages: 684-688
- NAID
  120001170074
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] EpCAM-Positive Hepatocellular Carcinoma Cells Are Tumor-Initiating Cells With Stem/Progenitor Cell Features.2009
- Author(s)
  T Yamashita, J Ji, A Budhu, M Forgues, W Yang, HY Wang, H Jia, Q Ye, LX Qin, E Wauthier, LM Reid, H Minato, M Honda, S Kaneko, ZY Tang, XW Wang.
- Journal Title
  
  Gastroenterology 136(3)
  
  Pages: 1012-1024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Differential microRNA expression between hepatitis B and hepatitis C leading disease progression to hepatocellular carcinoma.2009
- Author(s)
  S Ura, M Honda, T Yamashita, T Ueda, H Takatori, R Nishino, H Sunakozaka, Y Sakai, K Horimoto, S Kaneko.
- Journal Title
  
  Hepatology 49(4)
  
  Pages: 1098-1112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] J-shaped relationship between waist circumference and subsequent risk for Type 2 diabetes : an 8-year follow-up of relatively lean Japanese individuals.2009
- Author(s)
  M Sakurai, K Miura, T Takamura, M Ishizaki, Y Morikawa, K Nakamura, K Yoshita, T Kido, Y Naruse, S Kaneko, H Nakagawa.
- Journal Title
  
  Diabet Med 26(8)
  
  Pages: 753-759
- NAID
  120001507851
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Activation of lipogenic pathway correlates with cell proliferation and poor prognosis in hepatocellular carcinoma2009
- Author(s)
  Yamashita T, Honda M, Takatori H, Nishino R, Minato H, Takamura H, Ohta T, Kaneko S.
- Journal Title
  
  J Hepatol 50(1)
  
  Pages: 100-110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591161
[Journal Article] Activation of lipogenic pathway correlates with cell proliferation and poor prognosis in hepatocellular carcinoma.2009
- Author(s)
  T Yamashita, M Honda, H Takatori, R Nishino, H Minato, H Takamura, T Ohta, S Kaneko.
- Journal Title
  
  J Hepatology 50(1)
  
  Pages: 100-110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Obesity Upregulates Genes Involved in Oxidative Phosphorylation in Livers of Diabetic Patients2008
- Author(s)
  Takamura T, Misu H, Matsuzawa-Nagata N, Sakurai M, Ota T, Shimizu A, Kurita S, Takeshita Y, Ando H, Honda M, Kaneko S.
- Journal Title
  
  Obesity (Silver Spring) 16(12)
  
  Pages: 2601-2609
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591161
[Journal Article] Protein expression profile characteristic to hepatocellular carcinoma revealed by 2D-DIGE with supervised learning2008
- Author(s)
  Teramoto R, Minagawa H, Honda M, Miyazaki K, Tabuse Y, Kamijo K, Ueda T, Kaneko S.
- Journal Title
  
  Biochim Biophys Acta 1784(5)
  
  Pages: 764-772
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591161
[Journal Article] Increased oxidative stress precedes the onset of high-fat diet-induced insulin resistance and obesity2008
- Author(s)
  Matsuzawa-Nagata N, Takamura T, Ando H, Nakamura S, Kurita S, Misu H, Ota T, Yokoyama M, Honda M, Miyamoto K, Kaneko S.
- Journal Title
  
  Metabolism 57(8)
  
  Pages: 1071-1077
- NAID
  120001130340
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591161
[Journal Article] Comparative proteomic and transcriptomic profiling of the human hepatocellular carcinoma.2008
- Author(s)
  H Minagawa, M Honda, K Miyazaki, Y Tabuse, R Teramoto, T Yamashita, R Nishino, H Takatori, T Ueda, K Kamijo, S Kaneko.
- Journal Title
  
  Biochem Biophys Res Commun 366(1)
  
  Pages: 186-192
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Comparative analysis of proteome and transcriptome in human hepatocellular carcinoma using 2D-DIGE and SAGE2008
- Author(s)
  Minagawa H, Yamashita T, Honda M, Tabuse Y, Kamijo K, Tsugita A, Kaneko S.
- Journal Title
  
  Protein J. 27(7-8)
  
  Pages: 409-419
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591161
[Journal Article] Increased oxidative stress precedes the onset of high-fat diet-induced insulin resistance and obesity.2008
- Author(s)
  N Matsuzawa-Nagata, T Takamura, H Ando, S Nakamura, S Kurita, H Misu, T Ota, M Yokoyama, M Honda, K Miyamoto, S Kaneko.
- Journal Title
  
  Metabolism 57(8)
  
  Pages: 1071-1077
- NAID
  120001130340
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Identification of novel candidate tumour marker genes for intrahepatic cholangiocarcinoma2008
- Author(s)
  Nishino R, Honda M, Yamashita T, Takatori H, Minato H, Zen Y, Sasaki M, Takamura H, Horimoto K, Ohta T, Nakanuma Y, Kaneko S.
- Journal Title
  
  J Hepatol 49(2)
  
  Pages: 207-216
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591161
[Journal Article] Tranilast, an antifibrogenic agent, ameliorates a dietary rat model of nonalcoholic steatohepatitis.2008
- Author(s)
  M Uno, S Kurita, H Misu, H Ando, T Ota, N Matsuzawa-Nagata, Y Kita, S Nabemoto, H Akahori, Y Zen, Y Nakanuma, S Kaneko, T Takamura.
- Journal Title
  
  Hepatology 48(1)
  
  Pages: 109-118
- NAID
  120001130339
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Common transcriptional signature of tumor-infiltrating mononuclear inflammatory cells and peripheral blood mononuclear cells in hepatocellular carcinoma patients.2008
- Author(s)
  Y Sakai, M Honda, H Fujinaga, I Tatsumi, E Mizukoshi, Y Nakamoto, S Kaneko.
- Journal Title
  
  Cancer Res 68(24)
  
  Pages: 10267-10279
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Comparative proteomic and transcriptomic profiling of the human hepatocellular carcinoma2008
- Author(s)
  Minagawa H, Honda M, Miyazaki K, Tabuse Y, Teramoto R, Yamashita T, Nishino R, Takatori H, Ueda T, Kamijo K, Kaneko S.
- Journal Title
  
  Biochem Biophys Res Commun 366(1)
  
  Pages: 186-192
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591161
[Journal Article] Comparative analysis of proteome and transcriptome in human hepatocellular carcinoma using 2D-DIGE and SAGE.2008
- Author(s)
  H Minagawa, T Yamashita, M Honda, Y Tabuse, K Kamijo, A Tsugita, S Kaneko.
- Journal Title
  
  Protein J 27(7-8)
  
  Pages: 409-419
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Obesity upregulates genes involved in oxidative phosphorylation in livers of diabetic patients2008
- Author(s)
  T Takamura, H Misu, N Matsuzawa-Nagata, M Sakurai, T Ota, A Shimizu, S Kurita, Y Takeshita, H Ando, M Honda, S Kaneko
- Journal Title
  
  Obesity 16(12)
  
  Pages: 2061-2609
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] BMI may be better than waist circumference for defining metabolic syndrome in Japanese women.2008
- Author(s)
  M Sakurai, T Takamura, K Miura, S Kaneko, H Nakagawa.
- Journal Title
  
  Diabetes Care 31(3)
  
  Pages: 12-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] SAGE application in the study of diabetes.2008
- Author(s)
  T Takamura, H Misu, T Yamashita, S Kaneko.
- Journal Title
  
  Curr Pharm Biotechnol 9(5)
  
  Pages: 392-399
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Optimal amount of monocyte chemoattractant protein-1 enhances antitumor effects of suiside gene therapy against hepatocelluar carcinoma by M1 macrophage activation.2008
- Author(s)
  T Tsuchiyama, Y Nakamoto, Y Sakai, N Mukaida, S Kaneko.
- Journal Title
  
  Cancer Sci 99(10)
  
  Pages: 2075-2082
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Comparative analysis of proteome and transcriptome in human hepatocellular carcinoma using 2D-DIGE and SAGE2008
- Author(s)
  H Minagawa, T Yamashita, M Honda, Y Tabuse, K Kamijo, A Tsugita and S Kaneko.
- Journal Title
  
  Protein J 27(7-8)
  
  Pages: 409-419
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Olmesartan ameliorates a dietary rat model of non-alcoholic steatohepatitis through its pleiotropic effects.2008
- Author(s)
  S Kurita, T Takamura, T Ota, N Matsuzawa-Nagata, Y Kita, M Uno, S Nabemoto, K Ishikura, H Misu, H Ando, Y Zen, Y Nakanuma, S Kaneko.
- Journal Title
  
  Eur J Pharmacol 588(2-3)
  
  Pages: 316-324
- NAID
  120001130222
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Cross talk of tumor necrosis factor-alpha and the renin-angiotensin system in tumor necrosis factor-alpha-induced plasminogen activator inhibitor-1 production from hepatocytes.2008
- Author(s)
  Y Takeshita, T Takamura, H Ando, E Hamaguchi, A Takazakura, N Matsuzawa-Nagata, S Kaneko.
- Journal Title
  
  Eur J Pharmacol 579(1-3)
  
  Pages: 426-432
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Common transcriptional signature of tumor-infiltrating mononuclear inflammatory cells and peripheral blood mononuclear cells in hepatocellular carcinoma patients2008
- Author(s)
  Sakai Y, Honda M, Fujinaga H, Tatsumi I, Mizukoshi E, Nakamoto Y, Kaneko S.
- Journal Title
  
  Cancer Res 68(24)
  
  Pages: 10267-10279
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591161
[Journal Article] Protein expression profile characteristic to hepatocellular carcinoma revealed by 2D-DIGE with supervised learning.2008
- Author(s)
  R Teramoto, H Minagawa, M Honda, K Miyazaki, Y Tabuse, K Kamijo, T Ueda, S Kaneko.
- Journal Title
  
  Biochim Biophys Acta 1784(5)
  
  Pages: 764-772
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Expression of multidrug resistance-associated protein 3 and cytotoxic T cell responses in patients with hepatocellular carcinoma2008
- Author(s)
  Mizukoshi E, Honda M, Arai K, Yamashita T, Nakamoto Y, Kaneko S.
- Journal Title
  
  J Hepatol 49(6)
  
  Pages: 946-954
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591161
[Journal Article] Obesity upregulates genes involved in oxidative phosphorylation in livers of diabetic patients.2008
- Author(s)
  T Takamura, H Misu, N Matsuzawa-Nagata, M Sakurai, T Ota, A Shimizu, S Kurita, Y Takeshita, H Ando, M Honda, S Kaneko.
- Journal Title
  
  Obesity (Silver Spring) 16(12)
  
  Pages: 2601-2609
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Expression profiling of peripheral-blood mononuclear cells from patients with chronic hepatitis Cundergoing interferon therapy2007
- Author(s)
  Tateno M, Honda M, Kawamura T, Honda H, Kaneko S
- Journal Title
  
  J Infect Dis. 195(2)
  
  Pages: 255-67
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591161
[Journal Article] Insulin resistance accelerates a dietary rat model of nonalcoholic steatohepatitis2007
- Author(s)
  T Ota, T Takamura, S Kurita, N Matsuzawa, Y Kita, M Uno, H Akahori, H Misu, M Sakurai, Y Zen, Y Nakanuma and S Kaneko
- Journal Title
  
  Gastroenterology 132(1)
  
  Pages: 282-293
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Impact of diabetes mellitus on prognosis of patients infected with hepatitis C virus.2007
- Author(s)
  Y Kita, E Mizukoshi, T Takamura, M Sakurai, Y Takata, K Arai, T Yamashita, Y Nakamoto, S Kaneko.
- Journal Title
  
  Metabolism 56(12)
  
  Pages: 1682-1288
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Possible role of alpha-cell insulin resistance in exaggerated glucagon responses to arginine in type 2 diabetes.2007
- Author(s)
  N Tsuchiyama, T Takamura, H Ando, M Sakurai, A Shimizu, K Kato, S Kurita, S Kaneko.
- Journal Title
  
  Diabetes Care 30(10)
  
  Pages: 2583-2587
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Genes involved in oxidative phosphorylation are coordinately upregulated with fasting hyperglycaemia in livers of patients with type 2 diabetes2007
- Author(s)
  Misu H, Takamura T, Yamashita T, Honda M, Kaneko S., et al.
- Journal Title
  
  Diabetologia 50
  
  Pages: 268-277
- Data Source
  KAKENHI-PROJECT-17591036
[Journal Article] Association of the C825T polymorphism of the G-protein β3 subunit gene with hypertension, obesity, hyperlipidemia, insulin resistance, diabetes, diabetic complications, and diabetic therapies among Japanese.2007
- Author(s)
  T Hayakawa, T Takamura, T Abe, SKaneko.
- Journal Title
  
  Metabolism 56(1)
  
  Pages: 44-48
- NAID
  120000809436
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Infection of human hepatocyte chimeric mouse with genetically engineered hepatitis C virus and its susceptibility to interferon2007
- Author(s)
  Hiraga N, Imamura M, Tsuge M, Noguchi C, Takahashi S, Iwao E, Fujimoto Y, Abe H, Maekawa T, Ochi H, Tateno C, Yoshizato K, Sakai A, Sakai Y, Honda M, Kaneko S, Wakita T, Chayama K
- Journal Title
  
  FEBS Lett. 581(10)
  
  Pages: 1983-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591161
[Journal Article] Gene expression profiles in peripheral blood mononuclear cells reflect the pathophysiology of type 2 diabetes.2007
- Author(s)
  T Takamura, M Honda, Y Sakai, H Ando, A Shimizu, T Ota, M Sakurai, H Misu, S Kurita, N Matsuzawa-Nagata, M Uchikata, S Nakamura, R Matoba, M Tanino, K Matsubara, S Kaneko.
- Journal Title
  
  Biochem Biophys Res Commun 361(2)
  
  Pages: 379-384
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Genes involved in oxidative phosphorylation are coordinately upregulated with fasting hyperglycaemia in livers of patients with type 2 diabetes.2007
- Author(s)
  H Misu, T Takamura, N Matsuzawa, A Shimizu, T Ota, M Sakurai, H Ando, K Arai, T Yamashita, M Honda, T Yamashita, S Kaneko.
- Journal Title
  
  Diabetologia 50(2)
  
  Pages: 268-277
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Gene systems network inferred from expression profiles in hepatocellular carcinogenesis by graphical gaussian model2007
- Author(s)
  Aburatani S, Sun F, Saito S, Honda M, Kaneko S, Horimoto K.
- Journal Title
  
  EURASIP J Bioinform Syst Biol
  
  Pages: 47212-47212
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591161
[Journal Article] Insulin resistance accelerates a dietary rat model of nonalcoholic steatohepatitis.2007
- Author(s)
  T Ota, T Takamura, S Kurita, N Matsuzawa, Y Kita, M Uno, H Akahori, H Misu, M Sakurai, Y Zen, Y Nakanuma, S Kaneko.
- Journal Title
  
  Gastroenterology 132(1)
  
  Pages: 282-293
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Impact of diabetes on recurrence of hepatocellular carcinoma after surgical treatment in patients with viral hepatitis2007
- Author(s)
  Komura T, Mizukoshi E, Kita Y, Sakurai M, Takata Y, Arai K, Yamashita T, Ohta T, Shimizu K, Nakamoto Y, Honda M, Takamura T, Kaneko S.
- Journal Title
  
  Am J Gastroenterol 102(9)
  
  Pages: 1939-46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591161
[Journal Article] Gene expression profiles in peripheral blood mononuclear cells reflect the pathophysiology of type 2 diabetes2007
- Author(s)
  Takamura T, Honda M, Sakai Y, Ando H, Shimizu A, Ota T, Sakurai M, Misu H, Kurita S, Matsuzawa-Nagata N, Uchikata M, Nakamura S, Matoba R, Tanino M, Matsubara K, Kaneko S.
- Journal Title
  
  Biochem Biophys Res Commun 361(2)
  
  Pages: 379-84
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591161
[Journal Article] Pioglitazone in nonalcoholic steatohepatitis.2007
- Author(s)
  T Ota, T Takamura, S Kaneko.
- Journal Title
  
  N Engl J Med 356(10)
  
  Pages: 1068-1068
- NAID
  120000806619
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Selective estrogen receptor modulator raloxifene-associated aggravation of nonalcoholic steatohepatitis.2007
- Author(s)
  T Takamura, A Shimizu, H Ando, S Kaneko.
- Journal Title
  
  Intern Med 46(9)
  
  Pages: 579-581
- NAID
  130000078717
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Infection of human hepatocyte chimeric mouse with genetically engineered hepatitis C virus and its susceptibility to interferon.2007
- Author(s)
  Hiraga N, Imamura M, Tsuge M, Noguchi C, Takahashi S, Iwao E, Fujimoto Y, Abe H, Maekawa T, Ochi H, Tateno C, Yoshizato K, Sakai A, Sakai Y, Honda M, Kaneko S, Wakita T, Chayama K.
- Journal Title
  
  FEBS Lett. 581(10)
  
  Pages: 1983-1987
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591036
[Journal Article] Genes involved in oxidative phosphorylation are coordinately upregulated with fasting hyperglycaemia in livers of patients with type 2 diabetes2007
- Author(s)
  H Misu, T Takamura, N Matsuzawa, A Shimizu, T Ota, M Sakurai, H Ando, K Arai, T Yamashita, M Honda, T Yamashita and S Kaneko.
- Journal Title
  
  Diabetologia 50(2)
  
  Pages: 268-277
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Expression profiling of peripheral-blood mononuclear cells from patients with chronic hepatitis C undergoing interferon the rapy.2007
- Author(s)
  Tateno M, Honda M, Kawamura T, Honda H, Kaneko S.
- Journal Title
  
  J Infect Dis 195
  
  Pages: 255-67
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591161
[Journal Article] Lipid-induced oxidative stress causes steatohepatitis in mice fed an atherogenic diet2007
- Author(s)
  N Matsuzawa, T Takamura, S Kurita, H Misu, T Ota, H Ando, M Yokoyama, M Honda, Y Zen, Y Nakanuma, K Miyamoto and S Kaneko
- Journal Title
  
  Hepatology 46(5)
  
  Pages: 1392-1403
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Genes involved in oxidative phosphorylation are coordinately upregulated with fasting hyperglycaemia in livers of patients with type 2 diabetes2007
- Author(s)
  Misu H, Takamura T, Matsuzawa N, Shimizu A, Ota T, Sakurai M, Ando H, Arai K, Yamashita T, Honda M, Yamashita T, Kaneko S.
- Journal Title
  
  Diabetologia 50(2)
  
  Pages: 268-77
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591161
[Journal Article] Expression profiling of peripheral-blood mononuclear cells from patients with chronic hepatitis C undergoing interferon therapy2007
- Author(s)
  Tateno M, Honda M, Kawamura T, Honda H, Kaneko S.
- Journal Title
  
  J Infect Dis 195
  
  Pages: 255-267
- Data Source
  KAKENHI-PROJECT-17591036
[Journal Article] Factors associated with improvement of fasting plasma glucose level by mealtime dosing of a rapid-acting insulin analog in type 2 diabetes.2007
- Author(s)
  T Takamura, M Sakurai, M Nakamura, A Shimizu, T Ota, H Misu, Y Takeshita, N Tsuchiyama, S Kurita, H Ando, S Kaneko.
- Journal Title
  
  Diabetes Res Clin Pract 75(3)
  
  Pages: 278-284
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Expression profiling of peripheral-blood mononuclear cells from patients with chronic hepatitis C undergoing interferon therapy.2007
- Author(s)
  Tateno M, Honda M, Kawamura T, Honda H, Kaneko S.
- Journal Title
  
  J Infect Dis. 195(2)
  
  Pages: 255-67
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591036
[Journal Article] Lipid-induced oxidative stress causes steatohepatitis in mice fed an atherogenic diet2007
- Author(s)
  Matsuzawa N, Takamura T, Kurita S, Misu H, Ota T, Ando H, Yokoyama M, Honda M, Zen Y, Nakanuma Y, Miyamoto K, Kaneko S.
- Journal Title
  
  Hepatology 46(5)
  
  Pages: 1392-1403
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591161
[Journal Article] Liver steatosis, but not fibrosis, is associated with insulin resistance in nonalcoholic fatty liver disease.2007
- Author(s)
  M Sakurai, T Takamura, T Ota, H Ando, H Akahori, K Kaji, M Sasaki, Y Nakanuma, K Miura, S Kaneko.
- Journal Title
  
  J Gastroenterol 42(4)
  
  Pages: 312-317
- NAID
  10019483538
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Lipid-induced oxidative stress causes steatohepatitis in mice fed an atherogenic diet.2007
- Author(s)
  N Matsuzawa, T Takamura, S Kurita, H Misu, T Ota, H Ando, M Yokoyama, M Honda, Y Zen, Y Nakanuma, K Miyamoto, S Kaneko.
- Journal Title
  
  Hepatology 46(5)
  
  Pages: 1392-1403
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Regulation of adiponectin receptor expression in human liver and a hepatocyte cell line.2007
- Author(s)
  A Shimizu, T Takamura, N Matsuzawa, S Nakamura, S Nabemoto, Y Takeshita, H Misu, S Kurita, M Sakurai, M Yokoyama, Y Zen, M Sasaki, Y Nakanuma, S Kaneko.
- Journal Title
  
  Metabolism 56(11)
  
  Pages: 1478-1485
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Genes involved in oxidative phosphorylation are coordinately upregulated with fasting hyperglycaemia in livers of patients with type 2 diabetes.2007
- Author(s)
  Misu H, Takamura T, Matsuzawa N, Shimizu A, Ota T, Sakurai M, Ando H, Arai K, Yamashita T, Honda M, Yamashita T, Kaneko S.
- Journal Title
  
  Diabetologia. 50(2)
  
  Pages: 268-77
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591036
[Journal Article] Induction of reactive oxygen species from isolated rat glomeruli by protein kinase C activation and TNF-α stimulation, and effects of a phosphodiesterase inhibitor.2007
- Author(s)
  N Koike, T Takamura, S Kaneko.
- Journal Title
  
  Life Sci 80(18)
  
  Pages: 1721-1278
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Comment on : Nathan DM, Buse JB, Davidson MB et al. (2006) Management of hyperglycaemia in type 2 diabetes : a consensus algorithm for the initiation and adjustment of therapy. A consensus statement from the American Diabetes Association and the European Association for the Study of Diabetes.2007
- Author(s)
  Takamura, A Shimizu, H Ando, S Kaneko.
- Journal Title
  
  Diabetologia 50(1)
  
  Pages: 229-330
- NAID
  120000809528
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Gene systems network inferred from expression profiles in he patocellular carcinogenesis by graphical gaussian model2007
- Author(s)
  Aburatani S, Sun F, Saito S, Honda M, Kaneko S, Horimoto K.
- Journal Title
  
  EIJRASIP J Bioinform Syst Biol.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591161
[Journal Article] Secondary lymphoid tissue chemokine (SLC/CCL21)/CCR7 signaling regulates fibrocytes in renal fibrosis.2006
- Author(s)
  S Kaneko
- Journal Title
  
  P Natl Acad Sci USA 103(38)
  
  Pages: 14098-14103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Effect of hepatitis C virus (HCV) NS5B-nucleolin interaction on HCV replication with HCV subgenomic replicon.2006
- Author(s)
  Shimakami T, Honda M, Kusakawa T, Murata T, Shimotohno K, Kaneko S, Murakami S.
- Journal Title
  
  J Virol. 80(7)
  
  Pages: 3332-40
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591036
[Journal Article] Tumor necrosis factor-alpha-induced production of plasminogen activator inhibitor 1 and its regulation by pioglitazone and cerivastatin in a nonmalignant human hepatocyte cell line.2006
- Author(s)
  Y Takeshita, T Takamura, E Hamaguchi, A Shimizu, T Ota, M Sakurai, S Kaneko.
- Journal Title
  
  Metabolism 55(11)
  
  Pages: 1464-1472
- NAID
  120000809721
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Virological effects and safety of combined double filtration plasmapheresis (DFPP) and interferon therapy in patients with chronic hepatitis C : A preliminary study. Hepatol Res. 2006.36(3) : 167-75.2006
- Author(s)
  Yamashita T, Arai K, Sakai A, Mizukoshi E, Sakai Y, Kagaya T, Nakamoto Y, Honda M, Wada T, Yokoyama H, Kaneko S.
- Journal Title
  
  Hepatol Res. 36(3)1
  
  Pages: 67-75
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591036
[Journal Article] Clinical challenges and images in GI.Yersiniaenterocolitica mesenteric adenitis and terminal ileitis.2006
- Author(s)
  S Kaneko
- Journal Title
  
  Gastroenterology 131(5)
  
  Pages: 1379-1659
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Different signaling pathways in the livers of patients with chronic hepatitis B or chronic hepatitis C.2006
- Author(s)
  Honda M, Yamashita T, Ueda T, Takatori H, Nishino R, Kaneko S.
- Journal Title
  
  Hepatology. 44(5)
  
  Pages: 1122-38
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591036
[Journal Article] Different signaling pathways in the livers of patients with chronic hepatitis B or chronic hepatitis C.2006
- Author(s)
  M Honda, T Yamashita, T Ueda, H T, R Nishino, S Kaneko.
- Journal Title
  
  Hepatology 44(5)
  
  Pages: 1122-1138
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Different signaling pathways in the livers of patients with chronic hepatitis B or chronic hepatitis C2006
- Author(s)
  Honda M, Yamashita T, Ueda T, Takatori H, Nishino R, Kaneko S
- Journal Title
  
  Hepatology 44
  
  Pages: 167-175
- Data Source
  KAKENHI-PROJECT-17591036
[Journal Article] Erythrocyte sorbitol level as a predictor of the efficacy of epalrestat treatment for diabetic peripheral polyneuropathy.2006
- Author(s)
  H Ando, T Takamura, Y Nagai, S Kaneko.
- Journal Title
  
  J Diabetes Complications 20(6)
  
  Pages: 367-370
- NAID
  120000809564
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] The development and clinical features of splenic aneurysmassociated with liver cirrhosis.2006
- Author(s)
  Sunagozaka H, Tsuji H, Mizukoshi E, Arai K, Kagaya T, Yamashita T, Sakai A, Nakamoto Y, Honda M, Kaneko S.
- Journal Title
  
  Liver Int. 26(3)
  
  Pages: 291-7
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591036
[Journal Article] Pancreatic exocrine and endocrine events occur concomitantly but independently during the course of fulminant type 1 diabetes.2006
- Author(s)
  T Kahara, T Takamura, M Sakurai, H Misu, R Usuda, T Hayakawa, Y Nishimura, Y Bando, T Nagaoka, Y Nagai, S Kaneko.
- Journal Title
  
  Diabetes Res Clin Pract 71(3)
  
  Pages: 241-246
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Pure red cell aplasia associated with concomitant use of mycophenolate mofetil and ribavirin in post-transplant recurrent hepatitis C. Transpl Int. 2006. 19(2) : 170-12006
- Author(s)
  Hodo Y, Tsuji K, Mizukoshi E, Yamashita T, Sakai A, Nakamoto Y, Honda M, Kaneko S.
- Journal Title
  
  Transpl Int. 19(2)
  
  Pages: 170-1
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591036
[Journal Article] Virological effects and safety of combined double filtration plasmapheresis (DFPP) and interferon therapy in patients with chronic hepatitis C : A preliminary study2006
- Author(s)
  Yamashita T, Arai K, Sakai A, Honda M, Wada T, Yokoyama H, Kaneko S. et al.
- Journal Title
  
  Hepatol Res 36
  
  Pages: 977-979
- NAID
  10018640064
- Data Source
  KAKENHI-PROJECT-17591036
[Journal Article] The development and clinical features of splenic aneurysm associated with liver cirrhosis2006
- Author(s)
  Sunagozaka H, Tsuji H, Mizukoshi E, Arai K, Kagaya T, Yamashita T, Sakai A, Nakamoto Y, Honda M, Kaneko S.
- Journal Title
  
  Liver Int 26
  
  Pages: 291-297
- Data Source
  KAKENHI-PROJECT-17591036
[Journal Article] Effect of hepatitis C virus (HCV) NS5B-nucleolin interaction on HCV replication with HCV subgenomic replicon2006
- Author(s)
  Shimakami T, Honda M, Kusakawa T, Murata T, Shimotohno K, Kaneko S, Murakami S
- Journal Title
  
  J Virol 80
  
  Pages: 3332-3340
- Data Source
  KAKENHI-PROJECT-17591036
[Journal Article] Differential gene expression profiles in stage I primary biliary cirrhosis.2005
- Author(s)
  Honda M, Kawai H, Shirota Y, Yamashita T, Kaneko S.
- Journal Title
  
  Am J Gastroenterol 100(9)
  
  Pages: 2019-2030
- Data Source
  KAKENHI-PROJECT-17591036
[Journal Article] Ephrin-A1 expression contributes to the malignant characteristics of {alpha}-fetoprotein producing hepatocellular carcinoma.2005
- Author(s)
  Iida H, Honda M, Kawai HF, Yamashita T, Shirota Y, Wang BC, Miao H, Kaneko S.
- Journal Title
  
  Gut 54(6)
  
  Pages: 843-851
- Data Source
  KAKENHI-PROJECT-17591036
[Journal Article] La protein is a potent regulator of replication of hepatitis C virus in patients with chronic hepatitis C through internal ribosomal entry site-directed translation.2005
- Author(s)
  Honda M, Shimazaki T, Kaneko S.
- Journal Title
  
  Gastroenterology 128(2)
  
  Pages: 449-462
- Data Source
  KAKENHI-PROJECT-17591036
[Journal Article] Differential gene alteration among hepatoma cell lines demonstrated by cDNA microarray-based comparative genomic hybridization.2005
- Author(s)
  Kawaguchi K, Honda M, Yamashita T, Shirota Y, Kaneko S.
- Journal Title
  
  Biochem Biophys Res Commun 329(1)
  
  Pages: 370-380
- Data Source
  KAKENHI-PROJECT-17591036
[Journal Article] cDNA microarray analysis of autoimmune hepatitis, primary biliary cirrhosis and consecutive disease manifestation.2005
- Author(s)
  Honda M, Kawai H, Shirota Y, Yamashita T, Takamura T, Kaneko S.
- Journal Title
  
  J Autoimmun 25(2)
  
  Pages: 133-140
- Data Source
  KAKENHI-PROJECT-17591036
[Journal Article] Differential gene alteration among hepatoma cell lines demonstrated by cDNA microarray-based comparative genomic hybridization.2005
- Author(s)
  Kawaguchi K, Honda M, Yamashita T, Shirota Y, Kaneko S.
- Journal Title
  
  Biochem Biophys Res Commun. 329(1)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591036
[Journal Article] cDNA microarray analysis of autoimmune hepatitis, primary biliary cirrhosis and consecutive disease manifestation.2005
- Author(s)
  Honda M, Kawai H, Shirota Y, Yamashita T, Kaneko S.
- Journal Title
  
  J Autoimmun. 25(2)1
  
  Pages: 33-40
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591036
[Journal Article] Ephrin-Al expression contributes to the malignant characteristics of {alpha}-fetoprotein producing hepatocellular carcinoma. Gut. 2005 Jun;54(6) : 843-51.2005
- Author(s)
  Iida H, Honda M, Kawai HF, Yamashita T, Shirota Y, Wang BC, Miao H, Kaneko S.
- Journal Title
  
  Gut. 54(6)
  
  Pages: 843-51
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591036
[Journal Article] La protein is a potent regulator of replication of hepatitis C virus in patients with chronic hepatitis C through internal ribosomal entry site-directed translation.2005
- Author(s)
  Honda M, Shimazaki T, Kaneko S
- Journal Title
  
  Gastroenterology 128(2)
  
  Pages: 449-462
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591036
[Journal Article] La protein is a potent regulator of replication of hepatitis C virus in patients with chronic hepatitis C through internal ribosomal entry site-directed translation.2005
- Author(s)
  Honda M, Shimazaki T, Kaneko S.
- Journal Title
  
  Gastroenterology. 128(2)
  
  Pages: 449-62
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591036
[Journal Article] Clinical application of a DNA chip in the field of liver diseases2003
- Author(s)
  Shuichi Kaneko
- Journal Title
  
  Journal of Gastroenterology 38・Suppl XV
  
  Pages: 85-88
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13854015
[Journal Article] Clinical application of a DNA chip in> the field of liver diseases2003
- Author(s)
  Shuichi Kaneko
- Journal Title
  
  Journal of Gastroenterology 38-Suppel XV
  
  Pages: 85-88
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13854015
[Patent] 肝硬変の診断方法、非アルコール性脂肪肝炎及び肝細胞がんの合併症の診断方法並びに非アルコール性脂肪肝炎及び食道胃静脈瘤の合併症の診断方法2018
- Inventor(s)
  金子周一、本多政夫、川口和紀
- Industrial Property Rights Holder
  金沢大学
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-26253046
[Patent] 非アルコール性脂肪性肝炎治療剤2018
- Inventor(s)
  金子周一、酒井佳夫
- Industrial Property Rights Holder
  金沢大学
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-26253046
[Patent] 非アルコール性脂肪性肝炎治療剤2018
- Inventor(s)
  金子周一、酒井佳夫
- Industrial Property Rights Holder
  金沢大学
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Data Source
  KAKENHI-PLANNED-17H06393
[Patent] 肝硬変の診断方法、非アルコール性脂肪肝炎及び肝細胞がんの合併症の診断方法並びに非アルコール性脂肪肝炎及び食道胃静脈瘤の合併症の診断方法2018
- Inventor(s)
  金子周一、本多政夫、川口和紀
- Industrial Property Rights Holder
  金沢大学
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Data Source
  KAKENHI-PLANNED-17H06393
[Patent] 抗がん剤及び新規医薬のスクリーニング方法2017
- Inventor(s)
  山下太郎、金子周一、本多政夫、清木元治、岡田光
- Industrial Property Rights Holder
  金沢大学、興和株式会社
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-26253046
[Patent] 肝組織修復剤2017
- Inventor(s)
  酒井佳夫、金子周一、餅田初音
- Industrial Property Rights Holder
  金沢大学
- Industrial Property Rights Type
  特許
- Filing Date
  2017-03-01
- Data Source
  KAKENHI-PROJECT-26253046
[Patent] 線維化抑制剤2017
- Inventor(s)
  金子周一、本多政夫、岡田光
- Industrial Property Rights Holder
  金沢大学
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-26253046
[Patent] 線維化抑制剤2017
- Inventor(s)
  金子周一、本多政夫、岡田光
- Industrial Property Rights Holder
  金沢大学
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Data Source
  KAKENHI-PLANNED-17H06393
[Patent] 非アルコール性脂肪性肝炎検出方法、該肝炎の重篤度判定方法及び該肝炎の治療評価判定方法2017
- Inventor(s)
  酒井佳夫、金子周一、餅田初音
- Industrial Property Rights Holder
  金沢大学
- Industrial Property Rights Type
  特許
- Filing Date
  2017-02-17
- Data Source
  KAKENHI-PROJECT-26253046
[Patent] 肝細胞癌株、およびそれを用いた肝細胞癌発症動物モデル2017
- Inventor(s)
  金子周一、本多政夫、山下太郎、岡田光、村居和寿
- Industrial Property Rights Holder
  金沢大学
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-26253046
[Patent] 線維化抑制剤2016
- Inventor(s)
  金子周一、本多政夫、岡田光
- Industrial Property Rights Holder
  金沢大学
- Industrial Property Rights Type
  特許
- Filing Date
  2016-07-25
- Data Source
  KAKENHI-PROJECT-26253046
[Patent] ２型糖尿病患者の治療薬選択の補助方法，治療薬の効果予測方法及び検査方法2015
- Inventor(s)
  御簾博文、竹下有美枝、篁　俊成、金子周一
- Industrial Property Rights Holder
  金沢大学
- Industrial Property Rights Type
  特許
- Filing Date
  2015-09-10
- Overseas
- Data Source
  KAKENHI-PROJECT-26253046
[Patent] オリゴヌクレオチドが結合したビーズの作製方法2015
- Inventor(s)
  橋本真一、金子周一
- Industrial Property Rights Holder
  金沢大学
- Industrial Property Rights Type
  特許
- Filing Date
  2015-04-07
- Overseas
- Data Source
  KAKENHI-PROJECT-26253046
[Patent] 細胞障害性Ｔ細胞の作製方法2015
- Inventor(s)
  金子周一、水腰英四郎、中河秀俊、村口　篤、岸　裕幸、小林栄治
- Industrial Property Rights Holder
  金沢大学
- Industrial Property Rights Type
  特許
- Filing Date
  2015-10-23
- Data Source
  KAKENHI-PROJECT-26253046
[Patent] 抗Ｂ型肝炎ウイルス薬2015
- Inventor(s)
  橋本真一、金子周一、本多政夫、白崎尚芳、山下太郎
- Industrial Property Rights Holder
  金沢大学
- Industrial Property Rights Type
  特許
- Filing Date
  2015-11-09
- Data Source
  KAKENHI-PROJECT-26253046
[Patent] 抗DHCR24自己抗体検出による病態診断系2015
- Inventor(s)
  金子周一、小原恭子、小原道法、木村公則
- Industrial Property Rights Holder
  金沢大学
- Industrial Property Rights Type
  特許
- Filing Date
  2015-07-16
- Data Source
  KAKENHI-PROJECT-26253046
[Patent] ２型糖尿病患者の治療薬選択の補助方法，治療薬の効果予測方法及び検査方法2014
- Inventor(s)
  御簾　博文、竹下　有美枝、篁　俊成、金子　周一
- Industrial Property Rights Holder
  金沢大学
- Industrial Property Rights Type
  特許
- Filing Date
  2014-09-10
- Data Source
  KAKENHI-PROJECT-26253046
[Patent] 急性肝炎治療剤及び代謝異常治療剤2014
- Inventor(s)
  酒井　佳夫、金子　周一、関　晃裕、吉田　佳子、大和　雅敏
- Industrial Property Rights Holder
  金沢大学
- Industrial Property Rights Type
  特許
- Filing Date
  2014-07-10
- Data Source
  KAKENHI-PROJECT-26253046
[Patent] 脂肪組織由来間質細胞群を含む肝炎治療剤2010
- Inventor(s)
  東元真実、金子周一、酒井佳夫
- Industrial Property Rights Holder
  金沢大学
- Industrial Property Number
  2010-203796
- Filing Date
  2010-09-11
- Data Source
  KAKENHI-PROJECT-18109008
[Patent] 脂肪組織由来間質細胞群を含む肝炎治療剤2010
- Inventor(s)
  東元真実, 金子周一, 酒井佳夫
- Industrial Property Rights Holder
  金沢大学
- Industrial Property Number
  2010-203796
- Filing Date
  2010-09-11
- Data Source
  KAKENHI-PROJECT-18109008
[Patent] 腎症の進行度の判定方法並びに線維化抑制剤2010
- Inventor(s)
  坂井宣彦, 金子周一, 和田隆志
- Industrial Property Rights Holder
  金沢大学
- Industrial Property Number
  2010-281080
- Filing Date
  2010-12-16
- Data Source
  KAKENHI-PROJECT-18109008
[Patent] 遺伝子発現プロファイルによる消化器癌、胃癌、大腸癌及び膵臓癌の検出2009
- Inventor(s)
  金子周一、本多政夫、酒井佳夫、山下太郎
- Industrial Property Rights Holder
  金沢大学
- Industrial Property Number
  2009-193702
- Filing Date
  2009-08-24
- Data Source
  KAKENHI-PROJECT-18109008
[Patent] 遺伝子発現プロファイルによる消火器癌, 胃癌, 大腸癌及び膵臓癌の検出2009
- Inventor(s)
  金子周一, 本多政夫, 酒井佳夫
- Industrial Property Rights Holder
  国立大学法人金沢大学
- Industrial Property Number
  2009-193702
- Filing Date
  2009-08-24
- Data Source
  KAKENHI-PROJECT-18109008
[Patent] 生理的状態分析方法、生理的状態分析システム、及びコンピュータシステムに生理的状態を分析するための処理を実行させるコンピュータープログラム2008
- Inventor(s)
  松原謙一, 下田正文, 的場亮, 谷野元彦, 中村誠二, 岡山利次, 田村卓郎, 金子周一, 篁俊成, 河合昴三
- Industrial Property Rights Holder
  (株)DNAチップ研究所, ビッツ(株)
- Filing Date
  2008-12-05
- Data Source
  KAKENHI-PROJECT-18109008
[Patent] 生理的状態分析方法、生理的状態分析システム、及びコンピュータシステムに生理的状態を分析するための処理を実行させるコンピュータープログラム2008
- Inventor(s)
  松原謙一、下田正文、的場亮、谷野元彦、中村誠二、岡山利次、田村卓郎、金子周一、篁俊成、河合昴三
- Industrial Property Rights Holder
  (株) DNAチップ研究所、ビッツ(株)
- Industrial Property Number
  2008-311346
- Filing Date
  2008-12-05
- Data Source
  KAKENHI-PROJECT-18109008
[Patent] 糖尿病の病態と関連して発現変動する遺伝子群2005
- Inventor(s)
  金子周一, 篁俊成, 御簾博文
- Industrial Property Rights Holder
  (有)金沢大学テーエルオー
- Industrial Property Number
  2005-125689
- Filing Date
  2005-04-22
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13854015
[Patent] 腫瘍抗原ペプチド2004
- Inventor(s)
  金子周一, 水越英四郎, 中本安成, 辻宏和
- Industrial Property Rights Holder
  (有)金沢大学テーエルオー
- Industrial Property Number
  2004-056865
- Filing Date
  2004-03-01
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13854015
[Presentation] Hepatocellular Carcinoma and Pathogenesis2018
- Author(s)
  Taro Yamashita and Shuichi Kaneko
- Organizer
  25th International Symposium on Hepatitis C Virus and Related Viruses
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04695
[Presentation] 多様な癌幹細胞からなる肝細胞癌に対する最適な分子標的治療の検討2018
- Author(s)
  丹尾幸樹、山下太郎、金子周一
- Organizer
  日本消化器関連学会週間（JDDW）総会
- Data Source
  KAKENHI-PROJECT-16H04695
[Presentation] 末梢血リンパ球中の抗原特異的CD8^+T細胞およびT細胞受容体の網羅的・迅速解析2013
- Author(s)
  岸裕幸,小林栄治,水腰英四郎,小澤龍彦,浜名洋,長井輝美,中河秀俊,金艾順,金子周一,村口篤
- Organizer
  第5回造血器腫瘍免疫療法研究会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2013-08-24
- Data Source
  KAKENHI-PROJECT-24650630
[Presentation] がん抗原特異的TCR遺伝子の迅速クローニング法2013
- Author(s)
  小林栄治，水腰英四郎，岸　裕幸，金子周一，村口　篤
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24650630
[Presentation] Cloning of human antigen-specific TCRs can confer the candidates for cancer gene therapy.2013
- Author(s)
  Kobayashi E, Mizukoshi E, Kishi H, Hamana H, Nagai T, Ozawa T, Nakagawa H, Jin A, Kaneko S, Muraguchi A
- Organizer
  15th International Congress of Immunology
- Place of Presentation
  Milan
- Data Source
  KAKENHI-PROJECT-24650630
[Presentation] がんのTCR遺伝子治療にむけた候補TCR遺伝子の迅速クローニング法2012
- Author(s)
  岸裕幸,小林栄治,水腰英四郎,小澤龍彦,金子周一,村口篤
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24650630
[Presentation] C型肝炎ウイルス蛋白翻訳制御による複製抑2008
- Author(s)
  本多政夫, 島上哲朗, 金子周一
- Organizer
  第44回日本肝臓学会
- Place of Presentation
  松山市
- Year and Date
  2008-06-05
- Data Source
  KAKENHI-PROJECT-19591161
[Presentation] インターフェロン治療による肝組織内発現遺伝子プロファイルの検討2008
- Author(s)
  本多政夫, 酒井明人, 金子周一
- Organizer
  第12回日本肝臓学会
- Place of Presentation
  東京都
- Year and Date
  2008-10-01
- Data Source
  KAKENHI-PROJECT-19591161
[Presentation] Gene expression profiling in liver of chronic hepatitis C patients undergoing interferon therapy reveals the signaling pathway of interferon resistance2008
- Author(s)
  Honda M, Tateno M, Nakamura M, Sakai A, Kaneko S
- Organizer
  第15回 International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  アメリカ
- Year and Date
  2008-10-07
- Data Source
  KAKENHI-PROJECT-19591161
[Presentation] Cellular immune responses to multidrug resistance-associated protein 3 in the patients with hepatocellular carcinoma2008
- Author(s)
  Mizukoshi E, Arai K, Yamashita T, Nakamoto Y, Honda M, kaneko S
- Organizer
  第59回米国肝臓学会
- Place of Presentation
  アメリカ
- Year and Date
  2008-11-02
- Data Source
  KAKENHI-PROJECT-19591161
[Presentation] Gene expression profiling in liver of chronic hepatitis C patients undergoing interferon therapy reveals the signaling pathway of interferon resistance2008
- Author(s)
  Honda M, Tateno M, Nakamura M, Sakai A, Kaneko S.
- Organizer
  第15回International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  アメリカ
- Year and Date
  2008-10-07
- Data Source
  KAKENHI-PROJECT-19591161
[Presentation] Cellular immune responses to multidrug resistance-associated protein 3 in the patients with hepatocellular carcinoma2008
- Author(s)
  Mizukoshi E, Arai K, Yamashita T, Nakamoto Y, Honda M, Kaneko S.
- Organizer
  第59回アメリカ肝臓学会
- Place of Presentation
  アメリカ
- Year and Date
  2008-11-02
- Data Source
  KAKENHI-PROJECT-19591161
[Presentation] 慢性肝炎、肝細胞癌における鉄代謝関連因子の網羅的発現解析2007
- Author(s)
  本多政夫, 上田晃之, 金子周一
- Organizer
  第93回日本消化器病学会総会
- Place of Presentation
  青森市
- Year and Date
  2007-04-21
- Data Source
  KAKENHI-PROJECT-19591161
[Presentation] 慢性肝炎、肝細胞癌における鉄代謝関連因子の網羅的発現解析2007
- Author(s)
  本多政夫, 上田晃之, 金子周一
- Organizer
  第43回日本肝臓学会総会
- Place of Presentation
  東京都
- Year and Date
  2007-05-31
- Data Source
  KAKENHI-PROJECT-19591161
[Presentation] 慢性肝炎、肝細胞癌における鉄代謝関連因子の網羅的発現解析2007
- Author(s)
  本多政夫, 上田晃之, 金子周一
- Organizer
  第43回日本肝臓学会総会
- Place of Presentation
  東京
- Year and Date
  2007-05-31
- Data Source
  KAKENHI-PROJECT-19591161
[Presentation] 慢性肝炎、肝細胞癌における鉄代謝関連因子の網羅的発現解析2007
- Author(s)
  本多政夫, 上田晃之, 金子周一
- Organizer
  第93回目本消化器病学会総会
- Place of Presentation
  青森
- Year and Date
  2007-04-21
- Data Source
  KAKENHI-PROJECT-19591161
[Presentation] Comprehensive gene expression analysis of iron metabolism-related genes in patients with chronic viral hepatitis and hepatocellular carcinoma2007
- Author(s)
  Honda M, Ueda T, Yamashita T, Nishino R, Takatori H, Kaneko S.
- Organizer
  第58回アメリカ肝臓学会
- Place of Presentation
  アメリカ
- Year and Date
  2007-11-06
- Data Source
  KAKENHI-PROJECT-19591161
[Presentation] C型肝炎ウイルス感染に伴うヒト肝細胞キメラマウスの遺伝子発現プロフアイル解析2007
- Author(s)
  本多政夫, 今村道雄, 酒井明人, 酒井佳夫, 茶山一彰, 金子周一
- Organizer
  第93回日本消化器病学会総会
- Place of Presentation
  青森
- Year and Date
  2007-04-21
- Data Source
  KAKENHI-PROJECT-19591161
[Presentation] Comprehensive gene expression analysis of iron metabolism-related genes in patients with chronic viral hepatitis and hepatocel lularcar cinoma2007
- Author(s)
  Honda M, Ueda T, Yamashita T, Nishino R, Takatori H, Kaneko S
- Organizer
  第58 回米国肝臓学会
- Place of Presentation
  ボストン
- Year and Date
  2007-11-06
- Data Source
  KAKENHI-PROJECT-19591161
[Presentation] C型肝炎ウイルス感染に伴うヒト肝細胞キメラマウスの遺伝子発現プロファイル解析2007
- Author(s)
  本多政夫, 今村道雄, 酒井明人, 酒井佳夫, 茶山一彰, 金子周一
- Organizer
  第93回日本消化器病学会総会
- Place of Presentation
  青森市
- Year and Date
  2007-04-21
- Data Source
  KAKENHI-PROJECT-19591161
[Presentation] 末梢血リンパ球中の抗原特異的CD8+T細胞およびT細胞受容体の網羅的・迅速解析
- Author(s)
  岸　裕幸，小林栄治，水腰英四郎，小澤龍彦，浜名　洋，長井輝美，中河秀俊，金　艾順，金子周一，村口　篤
- Organizer
  第5回造血器腫瘍免疫療法研究会学術集会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24650630
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kaneko shuuichi 金子 周一

KANEKO Shuichi 金子 周一

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Elucidation of inflammation cellular society in liver cirrhosisPrincipal Investigator

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Study of the liver as an endocrine organPrincipal Investigator

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Liver producing hormones and life style related diseasesPrincipal Investigator

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Disturbance of hepatic function and over nutrition-related diseasesPrincipal Investigator

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宿主免疫のトランスクリプトーム解析を用いたC型肝炎ウイルスの持続感染機序研究Principal Investigator

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トランスクリプトーム技術を用いた肝細胞がんの早期診段開発研究Principal Investigator

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肝細胞におけるFunctionalGenomics解析系の確立Principal Investigator

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kaneko shuuichi 金子周一

KANEKO Shuichi 金子周一