takamura toshinari 篁俊成

… Alternative Names

TAKAMURA Toshinari 篁俊成

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Researcher Number	00324111
Other IDs
Affiliation (Current)	2023: 金沢大学, 医学系, 教授
Affiliation (based on the past Project Information) *help	2013 – 2023: 金沢大学, 医学系, 教授 2014: 金沢大学, 医薬保健研究域医学系, 教授 2008 – 2013: Kanazawa University, 医学系, 准教授 2007: 金沢大学, 医学系研究科, 准教授 2005 – 2006: 金沢大学, 医学系研究科, 助教授
Review Section/Research Field	Principal Investigator Metabolomics / Medium-sized Section 54:Internal medicine of the bio-information integration and related fields / Basic Section 54040:Metabolism and endocrinology-related Except Principal Investigator Gastroenterology / Endocrinology / Applied pharmacology / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
Keywords	Principal Investigator 糖尿病 / インスリン抵抗性 / 2型糖尿病 / 肝臓 / セレノプロテインP / エネルギー / 糖質代謝異常 / 肥満 / プロテアソーム / 肥満症 … More / 生体分子 / ヘパトカイン / 酸化ストレス / 還元ストレス / ホルモン / 分泌蛋白 / 発現遺伝子解析 / 小胞体ストレス / 蛋白代謝 / 糖代謝 / 脂質代謝 / insulin resistance / liver / proteasome / ER stress / obesity / type 2 diabetes / エネルギー代謝 / 脂肪肝 / タンパク質分解 / オートファジー / インスリン作用 / タンパク質代謝 / 遺伝子 / マイクロアレイ / 栄養学 / Diabetes / Gene / Microarray / Biomolecule / Nutrition / 活性酸素種 / 熱産生 / 褐色脂肪組織 / 骨粗鬆症 / 酸化還元ストレス / 酸化還元 / 褐色脂肪細胞 / 骨 / 酸化・還元ストレス / カテコラミン / ストレス / シグナル伝達 / 発生・分化 / サルコペニア / 薬剤スクリーニング / 運動効果 / 健康寿命 / 分泌タンパク質 / 化合物スクリーニング / 遺伝子発現 / 運動療法 / 骨格筋 / 非アルコール性脂肪性肝疾患 / 非アルコール性脂肪肝炎 / 肝臓遺伝子発現 / 脂肪肝炎 / バイオマーカー / 肝生検 / マルチオミクス / mRNAの機能 … More Except Principal Investigator 生活習慣病 / ゲノム / 発現制御 / 肝臓 / 栄養 / 糖尿病 / 橋本脳症 / 自己抗体 / 体内時計 / 概日リズム / 時計遺伝子 / 胚シグナル / 免疫寛容 / 幹細胞 / laeverin / プロテオミクス / 臨床解析 / 2D-DIGE / 小脳失調 / 糖新生 / 暁現象 / 臨床薬理学 / 時間治療 / 脳血管炎 / SPECT画像 / プロテオーム / 血管炎 / 脳血流 / 脳血流SPECT / 抗NAE抗体 / 分子診断マーカー / LIPS法 / 生物発光 / 肥満 / 免疫応答異常 / 自己免疫疾患 / 癌転移 Less

Selenoprotein P protein and mRNA functions in the diabetes pathologyPrincipal Investigator
- Principal Investigator
  
  篁俊成
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Kanazawa University
Functional analyses of selenoprotein P mRNA-binding proteins in brown/white adipose tissuesPrincipal Investigator
- Principal Investigator
  
  篁俊成
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Kanazawa University
新規胚シグナルlaeverinの幹細胞と免疫システムに対する作用の解明と臨床応用
- Principal Investigator
  
  藤原浩
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Kanazawa University
連続肝生検アプローチによる糖尿病性脂肪肝炎のバイオマーカー探索Principal Investigator
- Principal Investigator
  
  篁俊成
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  Kanazawa University
Identification and analysis of a new group of diseases with a common etiology of abnormal immune response to embryonic signals
- Principal Investigator
  
  Fujiwara Hiroshi
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Kanazawa University
Development of exercise-enhancing therapy targeting the liver-skeletal muscle networkPrincipal Investigator
- Principal Investigator
  
  Takamura Toshinari
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  Kanazawa University
Perturbation of redox balance in pathophysiology of diabetesPrincipal Investigator
- Principal Investigator
  
  Takamura Toshinari
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  Kanazawa University
Development of a new detection system of autoantibodies in Hashimoto encephalopathy and search for the pleiotropy
- Principal Investigator
  
  YONEDA Makoto
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  Fukui Prefectural University
Elucidation of pathophysiology and treatment strategies of peripheral clock disruption
- Principal Investigator
  
  ANDO Hitoshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Kanazawa University
Study of the liver as an endocrine organ
- Principal Investigator
  
  KANEKO Shuichi
- Project Period (FY)
  2014 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Gastroenterology
- Research Institution
  Kanazawa University
roles of intracellular proteolytic systems in maintaining energy metabolism homeostasisPrincipal Investigator
- Principal Investigator
  
  Takamura Toshinari
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Kanazawa University
Development of pharmacological therapy targeting peripheral circadian clocks for treatment of type 2 diabetes
- Principal Investigator
  
  ANDO Hitoshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Jichi Medical University
Molecular immunological study focussing on cerebral vasculitis in Hashimoto's encephalopathy associated with chronic thyroiditis
- Principal Investigator
  
  YONEDA Makoto
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  Fukui Prefectural University
  University of Fukui
Liver producing hormones and life style related diseases
- Principal Investigator
  
  KANEKO Shuichi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Gastroenterology
- Research Institution
  Kanazawa University
Significance of proteasome dysfunction in the development of obesity-mediated hepatic insulin resistancePrincipal Investigator
- Principal Investigator
  
  TAKAMURA Toshinari
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Kanazawa University
Clinical and immunological studies of autoimmune Hashimoto's encephalopathy associated with chronic thyroiditis
- Principal Investigator
  
  YONEDA Makoto
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  University of Fukui
Identification of a novel hepatokine that causes insulin resistance and diabetic vascular complicationsPrincipal Investigator
- Principal Investigator
  
  TAKAMURA Toshinari
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Kanazawa University
Disturbance of hepatic function and over nutrition-related diseases
- Principal Investigator
  
  KANEKO Shuichi
- Project Period (FY)
  2006 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Gastroenterology
- Research Institution
  Kanazawa University
Metabolic pathway altered in the liver of patients with type 2 diabetes and its regulationPrincipal Investigator
- Principal Investigator
  
  TAKAMURA Toshinari
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Kanazawa University

[Book] 内科学第12版2022
- Author(s)
  篁　俊成（矢﨑義雄、小室一成　編）
- Total Pages
  2572
- Publisher
  朝倉書店
- ISBN
  9784254322804
- Data Source
  KAKENHI-PROJECT-17H04199
[Book] 内科学第12版2022
- Author(s)
  篁　俊成（矢﨑義雄、小室一成　編）
- Total Pages
  2572
- Publisher
  朝倉書店
- ISBN
  9784254322804
- Data Source
  KAKENHI-PROJECT-21K19503
[Book] 「ビタミン欠乏症・過剰症・依存症」2021
- Author(s)
  篁俊成
- Total Pages
  3
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-18K19560
[Book] 「ビタミン欠乏症・過剰症・依存症」2021
- Author(s)
  篁俊成
- Total Pages
  3
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-17H04199
[Book] Non-Alcoholic Fatty Liver Diseases2019
- Author(s)
  Shuichi Kaneko, Toshinari Takamura, Hirofumi Misu
- Total Pages
  202
- Publisher
  Wiley
- ISBN
  9784939028687
- Data Source
  KAKENHI-PROJECT-18K19560
[Book] Non-Alcoholic Fatty Liver Diseases2019
- Author(s)
  Shuichi Kaneko, Toshinari Takamura, Hirofumi Misu
- Total Pages
  202
- Publisher
  Wiley
- ISBN
  9784939028687
- Data Source
  KAKENHI-PROJECT-17H04199
[Book] Ectopic Fat Accumulation in the Liver and Glucose Homeostasis (in Musculoskeletal Disease Associated with Diabetes Mellitus, Ed by Masaaki Inaba))2016
- Author(s)
  Toshinari Takamura, Hirofumi Misu, Shuichi Kaneko
- Total Pages
  296
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-26461329
[Book] 糖尿病2014
- Author(s)
  篁　俊成（分担執筆）
- Publisher
  西村書店
- Data Source
  KAKENHI-PROJECT-23591301
[Book] 糖尿病専門医研修ガイドブック改訂第6版2014
- Author(s)
  篁　俊成（分担執筆）
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-23591301
[Book] Team DiETの糖尿病療養メソッド2013
- Author(s)
  篁俊成(編)
- Total Pages
  133
- Publisher
  日本医事新報社,東京
- Data Source
  KAKENHI-PROJECT-23591301
[Book] Team DiETの糖尿病療養メソッド2013
- Author(s)
  篁　俊成（編著）
- Total Pages
  133
- Publisher
  日本医事新報社
- Data Source
  KAKENHI-PROJECT-23591301
[Book] 肝臓由来分泌蛋白セレノプロテインPとインスリン抵抗性.In「肝疾患Review 2012-2013」2012
- Author(s)
  篁俊成,金子周一(小俣政男監修、河田純男、横須賀收、工藤正俊、榎本信幸編)
- Publisher
  日本メディカルセンター,東京
- Data Source
  KAKENHI-PROJECT-23591301
[Book] BMI, waistcircumference and metabolic syndrome : Lessons from Japanese perspectives. In The Handbook of Anthropometry : Physical Measures of Human Form in Health and Disease2012
- Author(s)
  Sakurai M, Ota T, Miura K, Nakagawa H, Kaneko S, Takamura T (corresponding author).(V.R. Preedy, Eds.)
- Publisher
  Springer Science+Business Media, New York, USA
- Data Source
  KAKENHI-PROJECT-23591301
[Book] Annual Review 糖尿病・代謝・内分泌 2012（寺内康夫、伊藤　裕、石橋　俊　編）2012
- Author(s)
  御簾　博文，篁　俊成
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-23591301
[Book] 肝臓由来生理活性分子(ヘパトカイン)が形成する2型糖尿病の病態.In糖尿病学の進歩第46集2012
- Author(s)
  篁俊成(日本糖尿病学会編)
- Publisher
  診断と治療社,東京
- Data Source
  KAKENHI-PROJECT-23591301
[Book] 糖尿病・肥満患者における遺伝子発現変化(Annual Review糖尿病・代謝・内分泌)(寺内康夫、伊藤裕、石橋俊(編))2011
- Author(s)
  篁俊成
- Publisher
  中外医学社東京
- Data Source
  KAKENHI-PROJECT-20591054
[Book] 糖尿病・肥満患者における遺伝子発現変化、Annual Renew 2011糖尿病・代謝・内分泌2011
- Author(s)
  篁俊成
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-20591054
[Book] Annual Review 糖尿病・代謝・内分泌 2011（寺内康夫、伊藤　裕、石橋　俊　編）2011
- Author(s)
  篁　俊成
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-23591301
[Book] 糖尿病・肥満症患者における遺伝子発現変化In Annual Review糖尿病・代謝・内分泌20112011
- Author(s)
  篁俊成(寺内康夫、伊藤裕、石橋俊編)
- Publisher
  中外医学社,東京
- Data Source
  KAKENHI-PROJECT-23591301
[Book] 2型糖尿病治療のめざすところ、糖尿病チーム医療の教科書2010
- Author(s)
  篁俊成
- Publisher
  メジカルビュー社
- Data Source
  KAKENHI-PROJECT-20591054
[Book] 今すぐ始めるチーム医療、糖尿病チーム医療の教科書2010
- Author(s)
  篁俊成
- Publisher
  メジカルビュー社
- Data Source
  KAKENHI-PROJECT-20591054
[Book] 糖尿病性ケトアシドーシス・高血糖高浸透圧症候群.「栄養塾一症例で学ぶクリニカルパール」2010
- Author(s)
  篁俊成
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-20591054
[Book] 病態解明に迫る活性酸素シグナルと酸化ストレス-癌、神経変性疾患、循環・代謝異常にかかわるレドックス制御機構と最新の技術開発-(活性酸素がインスリンシグナル伝達に与える影響とその二面性)(谷口直之,赤池孝章,鈴木敬一郎,内田浩二(編))2009
- Author(s)
  御簾博文, 篁俊成
- Publisher
  羊土社東京
- Data Source
  KAKENHI-PROJECT-20591054
[Book] Annual Review 2009消化器(代謝臓器としての肝臓の分子生物学)(林紀夫,日比紀文,上西紀夫,下瀬川徹)2009
- Author(s)
  篁俊成, 金子周一
- Publisher
  中外医学社東京
- Data Source
  KAKENHI-PROJECT-20591054
[Book] 新時代の糖尿病学-病因・診断・治療研究の進歩-(糖質代謝異常)2008
- Author(s)
  篁俊成
- Publisher
  日本臨床大阪
- Data Source
  KAKENHI-PROJECT-20591054
[Book] 分子糖尿病の進歩2005-基礎から臨床まで-2005
- Author(s)
  篁俊成(分担執筆)
- Total Pages
  190
- Publisher
  金原出版
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590920
[Book] 臨床栄養ミニマムエッセンシャル2005
- Author(s)
  篁俊成(分担執筆)
- Publisher
  南江堂
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590920
[Journal Article] Insulin-glucagon‐like peptide‐1 receptor agonist relay and glucagon‐like peptide‐1 receptor agonist first regimens in individuals with type2 diabetes: A randomized, open‐label trial study2022
- Author(s)
  Takeshita Yumie、Takamura Toshinari、et al.
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: in press Issue: 6 Pages: 965-974
- DOI
  10.1111/jdi.13749
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04199
[Journal Article] Identification of ENPP1 Haploinsufficiency in Patients With Diffuse Idiopathic Skeletal Hyperostosis and Early‐Onset Osteoporosis2022
- Author(s)
  Kato Hajime、Ansh Anenya J、Lester Ethan R、Kinoshita Yuka、Hidaka Naoko、Hoshino Yoshitomo、Koga Minae、Taniguchi Yuki、Uchida Taisuke、Yamaguchi Hideki、Niida Yo、Nakazato Masamitsu、Nangaku Masaomi、Makita Noriko、Takamura Toshinari、Saito Taku、Braddock Demetrios T、Ito Nobuaki
- Journal Title
  
  Journal of Bone and Mineral Research
  
  Volume: - Issue: 6 Pages: 1125-1135
- DOI
  10.1002/jbmr.4550
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08246, KAKENHI-PROJECT-19K08996, KAKENHI-PROJECT-17H04199, KAKENHI-PROJECT-20K09451, KAKENHI-PROJECT-21K09293
[Journal Article] Lauric acid impairs insulin-induced Akt phosphorylation by upregulating SELENOP expression via HNF4α induction2022
- Author(s)
  Kamoshita Kyoko、Tsugane Hirohiko、Ishii Kiyo-aki、Takayama Hiroaki、Yao Xingyu、Abuduwaili Halimulati、Tanida Ryota、Taniguchi Yasumasa、Oo Hein Ko、Gafiyatullina Guzel、Kaneko Shuichi、Matsugo Seiichi、Takamura Toshinari
- Journal Title
  
  American Journal of Physiology-Endocrinology and Metabolism
  
  Volume: in press Issue: 6 Pages: E556-E568
- DOI
  10.1152/ajpendo.00163.2021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04199, KAKENHI-PROJECT-21K19503
[Journal Article] Selenoprotein P-mediated reductive stress impairs cold-induced thermogenesis in brown fat2022
- Author(s)
  Oo Swe Mar、Oo Hein Ko、Takayama Hiroaki、Ishii Kiyo-aki、Takeshita Yumie、Goto Hisanori、Nakano Yujiro、Kohno Susumu、Takahashi Chiaki、Nakamura Hiroyuki、Saito Yoshiro、Matsushita Mami、Okamatsu-Ogura Yuko、Saito Masayuki、Takamura Toshinari
- Journal Title
  
  Cell Reports
  
  Volume: 38 Issue: 13 Pages: 110566-110566
- DOI
  10.1016/j.celrep.2022.110566
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04199, KAKENHI-PROJECT-18K08507, KAKENHI-PROJECT-21K08572, KAKENHI-PROJECT-21K08573, KAKENHI-PROJECT-21K19503
[Journal Article] GHS-R1a deficiency mitigates lipopolysaccharide-induced lung injury in mice via the downregulation of macrophage activity2022
- Author(s)
  Tanida Ryota、Tsubouchi Hironobu、Yanagi Shigehisa、Saito Yusuke、Toshinai Koji、Miyazaki Taiga、Takamura Toshinari、Nakazato Masamitsu
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 589 Pages: 260-266
- DOI
  10.1016/j.bbrc.2021.12.044
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04199, KAKENHI-PROJECT-20K11499, KAKENHI-PROJECT-21K08159
[Journal Article] Forkhead box protein O1 (FoxO1) knockdown accelerates the eicosapentaenoic acid (EPA)-mediated <i>Selenop</i> downregulation independently of sterol regulatory element-binding protein-1c (SREBP-1c) in H4IIEC3 hepatocytes2022
- Author(s)
  K Kamoshita, N Tajima-Shirasaki, KA Ishii, T Shirasaki, H Takayama, H Abuduwaili, T Abuduyimiti, HK Oo, X Yao, Q Li, CM Galicia-Medina, S Kaneko, T Takamura.
- Journal Title
  
  Endocr J
  
  Volume: 69 Issue: 8 Pages: 907-918
- DOI
  10.1507/endocrj.EJ21-0392
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06393, KAKENHI-PROJECT-17H04199, KAKENHI-PROJECT-18K08507, KAKENHI-PROJECT-21K08573, KAKENHI-PROJECT-21K19503
[Journal Article] Role of selenoprotein P expression in the function of pancreatic β cells: Prevention of ferroptosis-like cell death and stress-induced nascent granule degradation2022
- Author(s)
  Kitabayashi Nanako、Nakao Shohei、Mita Yuichiro、Arisawa Kotoko、Hoshi Takayuki、Toyama Takashi、Ishii Kiyo-aki、Takamura Toshinari、Noguchi Noriko、Saito Yoshiro
- Journal Title
  
  Free Radical Biology and Medicine
  
  Volume: 183 Pages: 89-103
- DOI
  10.1016/j.freeradbiomed.2022.03.009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K11770, KAKENHI-PROJECT-17H04199, KAKENHI-PROJECT-18K08507, KAKENHI-PROJECT-21K08573
[Journal Article] A mosaic mutation of phosphate-regulating gene with homologies to endopeptidases on the X chromosome (<i>PHEX</i>) in X-linked hypophosphatemic rickets with mild bone phenotypes2021
- Author(s)
  Asano Shoko、Sako Saori、Funasaki Yuka、Takeshita Yumie、Niida Yo、Takamura Toshinari
- Journal Title
  
  Endocr J
  
  Volume: 68 Issue: 9 Pages: 1135-1141
- DOI
  10.1507/endocrj.EJ20-0809
- NAID
  130008093159
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04199, KAKENHI-PROJECT-19K08975
[Journal Article] Eight-year longitudinal study of whole blood gene expression profiles in individuals undergoing long-term medical follow-up2021
- Author(s)
  Sakai Yoshio、Nasti Alessandro、Takeshita Yumie、Okumura Miki、Kitajima Shinji、Honda Masao、Wada Takashi、Nakamura Seiji、Takamura Toshinari、Tamura Takuro、Matsubara Kenichi、Kaneko Shuichi
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 16564-16564
- DOI
  10.1038/s41598-021-96078-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04823, KAKENHI-PROJECT-17H04199, KAKENHI-PROJECT-19K08975, KAKENHI-PROJECT-21K19503
[Journal Article] LECT2 as a hepatokine links liver steatosis to inflammation via activating tissue macrophages in NASH2021
- Author(s)
  Takata Noboru、Ishii Kiyo-aki、Takayama Hiroaki、Nagashimada Mayumi、Kamoshita Kyoko、Tanaka Takeo、Kikuchi Akihiro、Takeshita Yumie、Matsumoto Yukako、Ota Tsuguhito、Yamamoto Yasuhiko、Yamagoe Satoshi、Seki Akihiro、Sakai Yoshio、Kaneko Shuichi、Takamura Toshinari
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 555-555
- DOI
  10.1038/s41598-020-80689-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08507, KAKENHI-PROJECT-19K08975, KAKENHI-PROJECT-20K17017, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06393, KAKENHI-PROJECT-17H04199, KAKENHI-PROJECT-18K06889, KAKENHI-PROJECT-18K19560, KAKENHI-PROJECT-19K23983
[Journal Article] Distinct effects of carbohydrate ingestion timing on glucose fluctuation and energy metabolism in patients with type 2 diabetes: a randomized controlled study2021
- Author(s)
  Enyama Yasufumi、Takeshita Yumie、Tanaka Takeo、Sako Saori、Kanamori Takehiro、Takamura Toshinari
- Journal Title
  
  Endocr J
  
  Volume: 68 Issue: 10 Pages: 1225-1236
- DOI
  10.1507/endocrj.EJ20-0623
- NAID
  130008111220
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04199, KAKENHI-PROJECT-19K08975, KAKENHI-PROJECT-21K19503
[Journal Article] Alcohol Intake Is Associated With Elevated Serum Levels of Selenium and Selenoprotein P in Humans2021
- Author(s)
  Isobe Yuki、Asakura Hiroki、Tsujiguchi Hiromasa、Kannon Takayuki、Takayama Hiroaki、Takeshita Yumie、Ishii Kiyo-aki、Kanamori Takehiro、Hara Akinori、Yamashita Tatsuya、Tajima Atsushi、Kaneko Shuichi、Nakamura Hiroyuki、Takamura Toshinari
- Journal Title
  
  Frontiers in Nutrition
  
  Volume: 8 Pages: 633703-633703
- DOI
  10.3389/fnut.2021.633703
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08507, KAKENHI-PROJECT-19KK0237, KAKENHI-PLANNED-17H06393, KAKENHI-PROJECT-17H04199, KAKENHI-PROJECT-18K19560
[Journal Article] Decline in serum albumin concentration is a predictor of serious events in nonalcoholic fatty liver disease2021
- Author(s)
  Kawaguchi Kazunori、Sakai Yoshio、Terashima Takeshi、Shimode Tetsuhiro、Seki Akihiro、Orita Noriaki、Takeshita Yumie、Shimakami Tetsuro、Takatori Hajime、Arai Kuniaki、Kitamura Kazuya、Yamashita Taro、Yamashita Tatsuya、Takamura Masayuki、Mizukoshi Eishiro、Takamura Toshinari、Honda Masao、Wada Takashi、Kaneko Shuichi
- Journal Title
  
  Medicine
  
  Volume: 100 Issue: 31 Pages: e26835-e26835
- DOI
  10.1097/md.0000000000026835
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04823, KAKENHI-PROJECT-17H04199, KAKENHI-PROJECT-19K08975, KAKENHI-PROJECT-21K19503, KAKENHI-PROJECT-20K16984
[Journal Article] Effects of eicosapentaenoic acid on serum levels of selenoprotein P and organ‐specific insulin sensitivity in humans with dyslipidemia and type 2 diabetes2021
- Author(s)
  Takeshita Yumie、Teramura Chisato、Kamoshita Kyoko、Takayama Hiroaki、Nakagawa Hiromi、Enyama Yasufumi、Ishii Kiyo‐Aki、Tanaka Takeo、Goto Hisanori、Nakano Yujiro、Osada Sachie、Tanaka Yoshiaki、Tokuyama Kumpei、Takamura Toshinari
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: 13 Issue: 3 Pages: 532-542
- DOI
  10.1111/jdi.13699
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04199, KAKENHI-PROJECT-20J11338, KAKENHI-PROJECT-18K08507, KAKENHI-PROJECT-19K08975, KAKENHI-PROJECT-21K08573, KAKENHI-PROJECT-21K19503
[Journal Article] Relationship between handgrip strength and albuminuria in community-dwelling elderly Japanese subjects: the Shika Study2020
- Author(s)
  Hara Akinori、Tsujiguchi Hiromasa、Suzuki Keita、Tao Yuichi、Nakamura Haruki、Kasahara Tomoko、Nguyen Thao Thi Thu、Miyagi Sakae、Shimizu Yukari、Kannon Takayuki、Tajima Atsushi、Wada Takashi、Takamura Toshinari、Nakamura Hiroyuki
- Journal Title
  
  Biomarkers
  
  Volume: 25 Issue: 7 Pages: 587-593
- DOI
  10.1080/1354750x.2020.1819418
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20309, KAKENHI-PROJECT-19K22751, KAKENHI-PROJECT-17H04199, KAKENHI-PROJECT-19H03882, KAKENHI-PROJECT-18K19560, KAKENHI-PROJECT-19K22753
[Journal Article] Acute Hyperenergetic, High-Fat Feeding Increases Circulating FGF21, LECT2, and Fetuin-A in Healthy Men2020
- Author(s)
  Willis Scott A、Sargeant Jack A、Yates Thomas、Takamura Toshinari、Takayama Hiroaki、Gupta Vinay、Brittain Emily、Crawford Joe、Parry Si?n A、Thackray Alice E、Varela-Mato Veronica、Stensel David J、Woods Rachel M、Hulston Carl J、Aithal Guruprasad P、King James A
- Journal Title
  
  The Journal of Nutrition
  
  Volume: 150 Issue: 5 Pages: 1076-1085
- DOI
  10.1093/jn/nxz333
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04199, KAKENHI-PROJECT-18K19560
[Journal Article] Secondary analyses to assess the profound effects of empagliflozin on endothelial function in patients with type?2 diabetes and established cardiovascular diseases: The placebo‐controlled double‐blind randomized effect of empagliflozin on endothelial function in cardiovascular high risk diabetes mellitus: Multi‐center placebo‐controlled double‐blind randomized trial2020
- Author(s)
  Tanaka Atsushi、Shimabukuro Michio、Machii Noritaka、Teragawa Hiroki、Okada Yosuke、Shima Kosuke R.、Takamura Toshinari、Taguchi Isao、Hisauchi Itaru、Toyoda Shigeru、Matsuzawa Yasushi、Tomiyama Hirofumi、Yamaoka‐Tojo Minako、Ueda Shinichiro、Higashi Yukihito、Node Koichi
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: 11 Issue: 6 Pages: 1551-1563
- DOI
  10.1111/jdi.13289
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K11371, KAKENHI-PROJECT-17H04199, KAKENHI-PROJECT-18K19560
[Journal Article] Metabolic and sympathovagal effects of bolus insulin glulisine versus basal insulin glargine therapy in people with type?2 diabetes: A randomized controlled study2020
- Author(s)
  Takeshita Yumie、Tanaka Takeo、Wakakuri Hitomi、Kita Yuki、Kanamori Takehiro、Takamura Toshinari
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: in press Issue: 7 Pages: 1193-1201
- DOI
  10.1111/jdi.13471
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04199, KAKENHI-PROJECT-18K19560, KAKENHI-PROJECT-19K08975
[Journal Article] Hepatokine Selenoprotein P-Mediated Reductive Stress Causes Resistance to Intracellular Signal Transduction2020
- Author(s)
  Takamura Toshinari
- Journal Title
  
  Antioxidants & Redox Signaling
  
  Volume: 33 Issue: 7 Pages: 517-524
- DOI
  10.1089/ars.2020.8087
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04199, KAKENHI-PROJECT-18K19560
[Journal Article] Plasma half-life and tissue distribution of leukocyte cell-derived chemotaxin 2 in mice2020
- Author(s)
  Kikuchi Akihiro、Takayama Hiroaki、Tsugane Hirohiko、Shiba Kazuhiro、Chikamoto Keita、Yamamoto Tatsuya、Matsugo Seiichi、Ishii Kiyo-aki、Misu Hirofumi、Takamura Toshinari
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 13260-13260
- DOI
  10.1038/s41598-020-70192-x
- NAID
  120007185663
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08507, KAKENHI-PROJECT-19K06604, KAKENHI-PROJECT-17H04199, KAKENHI-PROJECT-18K19560
[Journal Article] Circulating Concentrations of Insulin Resistance-Associated Hepatokines, Selenoprotein P and Leukocyte Cell-Derived Chemotaxin 2, during an Oral Glucose Tolerance Test in Humans2019
- Author(s)
  Mohri K, Misu H, Takayama H, Ishii KA, Kikuchi A, Lan F, Enyama Y, Takeshita Y, Saito Y, Kaneko S,Takamura T.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 42 Issue: 3 Pages: 373-378
- DOI
  10.1248/bpb.b18-00549
- NAID
  130007607371
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2019-03-01
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09739, KAKENHI-PROJECT-16K09740, KAKENHI-PROJECT-18K08507, KAKENHI-PROJECT-18K19560, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06393, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-19K08975, KAKENHI-PROJECT-17H04199, KAKENHI-PROJECT-17K09822, KAKENHI-PROJECT-17H03821
[Journal Article] p62-mediated autophagy affects nutrition-dependent insulin receptor substrate 1 dynamics in 3T3-L1 preadipocytes2019
- Author(s)
  Igawa Hirobumi、Kikuchi Akihiro、Misu Hirofumi、Ishii Kiyo-aki、Kaneko Shuichi、Takamura Toshinari
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: 10 Issue: 1 Pages: 32-42
- DOI
  10.1111/jdi.12866
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09822, KAKENHI-PROJECT-18K08507, KAKENHI-PROJECT-18K19560, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-17H04199
[Journal Article] Induction of Selenoprotein P mRNA during Hepatitis C Virus Infection Inhibits RIG-I-Mediated Antiviral Immunity.2019
- Author(s)
  Murai K, Honda M, Shirasaki T, Shimakami T, Omura H, Misu H, Kita Y, Takeshita Y, Ishii KA, Takamura T, Urabe T, Shimizu R, Okada H, Yamashita T, Sakai Y, Kaneko S.
- Journal Title
  
  Cell Host Microbe
  
  Volume: 10;25(4) Issue: 4 Pages: 588-601
- DOI
  10.1016/j.chom.2019.02.015
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15933, KAKENHI-PROJECT-18K08507, KAKENHI-PROJECT-19K08975, KAKENHI-PROJECT-18K19560, KAKENHI-PROJECT-19K17427, KAKENHI-PLANNED-17H06393, KAKENHI-PROJECT-17H04199, KAKENHI-PROJECT-18H02793, KAKENHI-PROJECT-16K09739, KAKENHI-PROJECT-16K09740, KAKENHI-PROJECT-17K09413
[Journal Article] Serum selenoprotein P, but not selenium, predicts future hyperglycemia in a general Japanese population.2018
- Author(s)
  Oo SM, Misu H, Saito Y, Tanaka M, Kato S, Kita Y, Takayama H, Takeshita Y, Kanamori T, Nagano T, Nakagen M, Urabe T, Matsuyama N, Kaneko S, Takamura T.
- Journal Title
  
  Sci Rep.
  
  Volume: 8 Issue: 1 Pages: 16727-16727
- DOI
  10.1038/s41598-018-35067-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09739, KAKENHI-PROJECT-16K09740, KAKENHI-PROJECT-18K19560, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06393, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-17H04199, KAKENHI-PROJECT-17H03821
[Journal Article] Ursodeoxycholic acid potentiates dipeptidyl peptidase-4 inhibitor sitagliptin by enhancing glucagon-like peptide-1 secretion in patients with type 2 diabetes and chronic liver disease: a pilot randomized controlled and add-on study2018
- Author(s)
  K. R. Shima, T. Ota, K. I. Kato, Y. Takeshita, H. Misu, S. Kaneko and T. Takamura
- Journal Title
  
  BMJ Open Diabetes Res Care
  
  Volume: 6 Issue: 1 Pages: e000469-e000469
- DOI
  10.1136/bmjdrc-2017-000469
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09740, KAKENHI-PROJECT-16K19533, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-17H04199, KAKENHI-PROJECT-16H03035
[Journal Article] Endogenous Selenoprotein P, a Liver-Derived Secretory Protein, Mediates Myocardial Ischemia/Reperfusion Injury in Mice.2018
- Author(s)
  Chikata A, Kato T, Usuda K, Fujita S, Maruyama M, Nagata Y, Sakagami S, Kanamori N, Yaegashi T, Saeki T, Kusayama T, Usui S, Furusho H, Kaneko S, Takamura M.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 19 Issue: 3 Pages: 878-878
- DOI
  10.3390/ijms19030878
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09425, KAKENHI-PROJECT-16K09740, KAKENHI-PROJECT-15K09135, KAKENHI-PROJECT-18K19560, KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-17H04199
[Journal Article] Effects of metformin and alogliptin on body composition in people with type 2 diabetes.2018
- Author(s)
  Takeshita Y, Kita Y, Kato KI, Kanamori T, Misu H, Kaneko, Takamura T.
- Journal Title
  
  J Diabetes Investig
  
  Volume: Aug Issue: 3 Pages: 29-29
- DOI
  10.1111/jdi.12920
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09739, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-19K08975
[Journal Article] Inhibin betaE (INHBE) is a possible insulin resistance-associated hepatokine identified by comprehensive gene expression analysis in human liver biopsy samples2018
- Author(s)
  M. Sugiyama, A. Kikuchi, H. Misu, H. Igawa, M. Ashihara, Y. Kushima, K. Honda, Y. Suzuki, Y. Kawabe, S. Kaneko and T. Takamura
- Journal Title
  
  PLoS One
  
  Volume: 13 Issue: 3 Pages: e0194798-e0194798
- DOI
  10.1371/journal.pone.0194798
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09740, KAKENHI-PROJECT-17K09822, KAKENHI-PROJECT-17H04199, KAKENHI-ORGANIZER-17H06391
[Journal Article] Comparison of Human Selenoprotein P Determinants in Serum between Our Original Methods and Commercially Available Kits2018
- Author(s)
  Saito Yoshiro、Misu Hirofumi、Takayama Hiroaki、Takashima Shin-ichiro、Usui Soichiro、Takamura Masayuki、Kaneko Shuichi、Takamura Toshinari、Noguchi Noriko
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 41 Issue: 5 Pages: 828-832
- DOI
  10.1248/bpb.b18-00046
- NAID
  130006730702
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2018-05-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19560, KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-17H04199, KAKENHI-PROJECT-16K09425, KAKENHI-PROJECT-17H03821
[Journal Article] High-carb or low-carb, that is a question (Commentary)2017
- Author(s)
  Igawa H, Takamura T
- Journal Title
  
  Diabetol Int
  
  Volume: 8 Issue: 1 Pages: 1-3
- DOI
  10.1007/s13340-016-0296-5
- Open Access
- Data Source
  KAKENHI-PROJECT-26461329
[Journal Article] Eicosapentaenoic acid down-regulates expression of the selenoprotein P gene by inhibiting SREBP-1c protein independently of the AMP-activated protein kinase pathway in H4IIEC3 hepatocytes.2017
- Author(s)
  Tajima-Shirasaki N, Ishii KA, Takayama H, Shirasaki T, Iwama H, Chikamoto K, Saito Y, Iwasaki Y, Teraguchi A, Lan F, Kikuchi A, Takeshita Y, Murao K, Matsugo S, Kaneko S, Misu H, Takamura T.
- Journal Title
  
  J Biol Chem.
  
  Volume: 292 Issue: 26 Pages: 10791-10800
- DOI
  10.1074/jbc.m116.747006
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09739, KAKENHI-PROJECT-16K09740, KAKENHI-PROJECT-16K21058, KAKENHI-PLANNED-17H06393, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-17H04199, KAKENHI-PROJECT-17H03821
[Journal Article] Weight-adjusted lean body mass and calf circumference are protective against obesity-associated insulin resistance and metabolic abnormalities.2017
- Author(s)
  Takamura T, Kita Y, Nakagen M, Sakurai M, Isobe Y, Takeshita Y, Kawai K, Urabe T, Kaneko S.
- Journal Title
  
  Heliyon.
  
  Volume: 3 Issue: 7 Pages: e00347-e00347
- DOI
  10.1016/j.heliyon.2017.e00347
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09739, KAKENHI-PLANNED-17H06393, KAKENHI-PROJECT-17H04199
[Journal Article] Deficiency of the hepatokine selenoprotein P increases responsiveness to exercise in mice through upregulation of reactive oxygen species and AMP-activated protein kinase in muscle.2017
- Author(s)
  H Misu, H Takayama, Y Saito, Y Mita, A Kikuchi, K Ishii, K Chikamoto, T Kanamori, N Tajima, F Lan, Y Takeshita, M Honda, M Tanaka, S Kato, N Matsuyama, Y Yoshioka, Iwayama K, Tokuyama K, Akazawa N, Maeda S, Takekoshi K, Matsugo S, Noguchi N, S Kaneko, T Takamura.
- Journal Title
  
  Nature Med
  
  Volume: 23 Issue: 4 Pages: 508-516
- DOI
  10.1038/nm.4295
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-15H04809, KAKENHI-PROJECT-26461328, KAKENHI-PROJECT-26461329, KAKENHI-PROJECT-16K15426, KAKENHI-PROJECT-16K09739, KAKENHI-PROJECT-16K09740, KAKENHI-PROJECT-25292078, KAKENHI-PROJECT-17H04199
[Journal Article] Branched-chain amino acids prevent hepatic fibrosis and development of hepatocellular carcinoma in a non-alcoholic steatohepatitis mouse model.2017
- Author(s)
  K Takegoshi, M Honda, H Okada, R Takabatake, N Matsuzawa-Nagata, JS Campbell, M Nishikawa, T Shimakami, T Shirasaki, Y Sakai, T Yamashita, T Takamura, T Tanaka, S Kaneko.
- Journal Title
  
  Oncotarget
  
  Volume: 印刷中 Issue: 11 Pages: 18191-18205
- DOI
  10.18632/oncotarget.15304
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-15H04809, KAKENHI-PROJECT-26460995, KAKENHI-PROJECT-16K15426, KAKENHI-PROJECT-16K21058
[Journal Article] Selenoprotein P-neutralizing antibodies improve insulin secretion and glucose sensitivity in type 2 diabetes mouse models2017
- Author(s)
  Mita Yuichiro、Nakayama Kaho、Inari Shogo、Nishito Yukina、Yoshioka Yuya、Sakai Naoko、Sotani Kanade、Nagamura Takahiro、Kuzuhara Yuki、Inagaki Kumi、Iwasaki Miki、Misu Hirofumi、Ikegawa Masaya、Takamura Toshinari、Noguchi Noriko、Saito Yoshiro
- Journal Title
  
  Nature Communications
  
  Volume: 8 Issue: 1 Pages: 1658-1658
- DOI
  10.1038/s41467-017-01863-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09740, KAKENHI-PROJECT-16K18707, KAKENHI-PROJECT-17H04199, KAKENHI-PROJECT-17H03821
[Journal Article] The influence of adiposity and acute exercise on circulating hepatokines in normal-weight and overweight/obese men2017
- Author(s)
  Sargeant Jack A.、Aithal Guruprasad P.、Takamura Toshinari、Misu Hirofumi、Takayama Hiroaki、Douglas Jessica A.、Turner Mark C.、Stensel David J.、Nimmo Myra A.、Webb David R.、Yates Thomas、King James A.
- Journal Title
  
  Appl Physiol Nutr Metab
  
  Volume: 3 Issue: 5 Pages: 1-9
- DOI
  10.1139/apnm-2017-0639
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09740, KAKENHI-PROJECT-18K19560, KAKENHI-PROJECT-17H04199
[Journal Article] Corrigendum to 'Weight-adjusted lean body mass and calf circumference are protective against obesity-associated insulin resistance and metabolic abnormalities'.2017
- Author(s)
  T Takamura, Y Kita, M Nakagen, M Sakurai, Y Isobe, Y Takeshita, K Kawai, T Urabe, S Kaneko.
- Journal Title
  
  Heliyon
  
  Volume: 3 Issue: 7 Pages: e00363-e00363
- DOI
  10.1016/j.heliyon.2017.e00363
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06393, KAKENHI-PROJECT-26253046
[Journal Article] Where does liver fat go? A possible molecular link between fatty liver and diabetes2017
- Author(s)
  Akihiro Kikuchi, Toshinari Takamura
- Journal Title
  
  J. Diabetes Invest
  
  Volume: 8 Issue: 2 Pages: 152-154
- DOI
  10.1111/jdi.12573
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461328, KAKENHI-PROJECT-26461329
[Journal Article] Once-weekly glucagon-like peptide-1 receptor agonist dulaglutide significantly decreases glycated haemoglobin compared with once-daily liraglutide in Japanese patients with type 2 diabetes: 52 weeks of treatment in a randomized phase III study2016
- Author(s)
  Odawara M, Miyagawa J, Iwamoto N, Takita Y, Imaoka T, Takamura T
- Journal Title
  
  Diabetes Obes Metab
  
  Volume: 18 Issue: 3 Pages: 249-257
- DOI
  10.1111/dom.12602
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461329
[Journal Article] Fat-free mass and calf circumference as body composition indices to determine non-exercise activity thermogenesis in patients with diabetes2016
- Author(s)
  Y. Isobe, M. Sakurai, Y. Kita, Y. Takeshita, H. Misu, S. Kaneko, T. Takamura
- Journal Title
  
  J Diabetes Investig
  
  Volume: 7 Issue: 3 Pages: 352-358
- DOI
  10.1111/jdi.12421
- NAID
  120005682647
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461329, KAKENHI-PROJECT-16K09740
[Journal Article] Rapid response of the steatosis-sensing hepatokine LECT2 during diet-induced weight cycling in mice.2016
- Author(s)
  K Chikamoto, H Misu, H Takayama, A Kikuchi, KA Ishii, F Lan, N Takata, N Tajima-Shirasaki, Y Takeshita, H Tsugane, S Kaneko, S Matsugo, T Takamura.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 478 Issue: 3 Pages: 1310-1316
- DOI
  10.1016/j.bbrc.2016.08.117
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-26461328, KAKENHI-PROJECT-26461329, KAKENHI-PROJECT-26461377, KAKENHI-PROJECT-16K09740
[Journal Article] Pleiotropic effects of sitagliptin versus voglibose in patients with type 2 diabetes inadequately controlled via diet and/or a single oral antihyperglycemic agent: a multicenter, randomized trial2016
- Author(s)
  Matsushima Y, Takeshita Y, Kita Y, Otoda T, Kato K, Toyama-Wakakuri H, Akahori H, Shimizu A, Hamaguchi E, Nishimura Y, Kanamori T, Kaneko S, Takamura T
- Journal Title
  
  BMJ Open Diabetes Res Care
  
  Volume: 4 Issue: 1 Pages: e000190-e000190
- DOI
  10.1136/bmjdrc-2015-000190
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461329
[Journal Article] Development of a Sol Particle Homogeneous Immunoassay for Measuring Full-Length Selenoprotein P in Human Serum.2016
- Author(s)
  M. Tanaka, Y. Saito, H. Misu, S. Kato, Y. Kita, Y. Takeshita, T. Kanamori, T. Nagano, M. Nakagen, T. Urabe, T. Takamura, S. Kaneko, K. Takahashi and N. Matsuyama.
- Journal Title
  
  J Clin Lab Anal
  
  Volume: 30 Issue: 2 Pages: 114-122
- DOI
  10.1002/jcla.21824
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461334, KAKENHI-PROJECT-25292078, KAKENHI-PROJECT-26461329, KAKENHI-PROJECT-16K09740
[Journal Article] Response to Importance of confounding factors in assessing fatty acid compositions in patients with non-alcoholic steatohepatitis2015
- Author(s)
  Yamada K, Mizukoshi E, Sunagozaka H, Arai K, Yamashita T, Takeshita Y, Misu H, Takamura T, Kitamura S, Zen Y, Nakanuma Y, Honda M, Kaneko S
- Journal Title
  
  Liver Int
  
  Volume: 35 Issue: 6 Pages: 1773-1773
- DOI
  10.1111/liv.12755
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461329, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-15H04809, KAKENHI-PROJECT-26670378
[Journal Article] Physiological roles of peroxido-vanadium complexes: Leitmotif as their signal transduction pathway (Review)2015
- Author(s)
  Matsugo S, Kanamori K, Sugiyama H, Misu H, Takamura T
- Journal Title
  
  J Inorg Biochem
  
  Volume: Epub 2015 Feb 25 Pages: 93-98
- DOI
  10.1016/j.jinorgbio.2015.02.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461329
[Journal Article] Bending of a vertical cannula without alarm during insulin pump therapy as a cause of unexpected hyperglycemia: A Japanese issue?2015
- Author(s)
  Kuroda K, Takeshita Y, Kaneko S, Takamura T
- Journal Title
  
  J Diabetes Investig
  
  Volume: 6 Issue: 6 Pages: 739-740
- DOI
  10.1111/jdi.12357
- NAID
  120005689372
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461329, KAKENHI-PROJECT-26253046
[Journal Article] Sitagliptin versus mitiglinide switched from mealtime dosing of a rapid-acting insulin analog in patients with type 2 diabetes: a randomized, parallel-group study2015
- Author(s)
  Takeshita Y, Takamura T, Kita Y, Takazakura A, Kato K, Isobe Y, Kaneko S
- Journal Title
  
  BMJ Open Diabetes Res Care
  
  Volume: 3 Issue: 10 Pages: 974-983
- DOI
  10.1111/dom.12534
- NAID
  120005774893
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461329
[Journal Article] Hepatocellular Carcinoma with β-Catenin Mutation: Imaging and Pathologic Characteristics.2015
- Author(s)
  Kitao A, Matsui O, Yoneda N, Kozaka K, Kobayashi S, Sanada J, Koda W, Minami T, Inoue D, Yoshida K, Yamashita T, Yamashita T, Kaneko S, Takamura H, Ohta T, Ikeda H, Nakanuma Y, Kita R, Gabata T.
- Journal Title
  
  Radiology.
  
  Volume: 275 Issue: 3 Pages: 708-717
- DOI
  10.1148/radiol.14141315
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461819, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-25461805, KAKENHI-PROJECT-25461873, KAKENHI-PROJECT-26860986
[Journal Article] Whole exome sequencing combined with integrated variant annotation prediction identifies asymptomatic Tangier disease with compound heterozygous mutations in ABCA1 gene.2015
- Author(s)
  Tada H, Kawashiri MA, Nohara A, Saito R, Tanaka Y, Nomura A, Konno T, Sakata K, Fujino N, Takamura T, Inazu A, Mabuchi H, Yamagishi M, Hayashi K.
- Journal Title
  
  Atherosclerosis.
  
  Volume: 240 Issue: 2 Pages: 324-9
- DOI
  10.1016/j.atherosclerosis.2015.04.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591041, KAKENHI-PROJECT-15K09118, KAKENHI-PROJECT-26461329
[Journal Article] Liver steatosis is associated with insulin resistance in skeletal muscle rather than in the liver in Japanese patients with non-alcoholic fatty liver disease.2015
- Author(s)
  Kato K, Takeshita Y, Misu H, Zen Y, Kaneko S, Takamura T.
- Journal Title
  
  J Diabetes Investig.
  
  Volume: 6 Issue: 2 Pages: 158-163
- DOI
  10.1111/jdi.12271
- NAID
  120005593987
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461334, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-26461329, KAKENHI-PROJECT-15K08345
[Journal Article] Sitagliptin versus mitiglinide switched from mealtime dosing of a rapid-acting insulin analog in patients with type 2 diabetes: a randomized, parallel-group study.2015
- Author(s)
  Y Takeshita, T Takamura, Y Kita, A Takazakura, K Kato, Y Isobe, S Kaneko.
- Journal Title
  
  BMJ Open Diabetes Res Care
  
  Volume: 3 Issue: 1 Pages: e000122-e000122
- DOI
  10.1136/bmjdrc-2015-000122
- NAID
  120005774893
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26253046
[Journal Article] Renoprotective effects of atorvastatin compared with pravastatin on progression of early diabetic nephropathy2015
- Author(s)
  Takazakura A, Sakurai M, Bando Y, Misu H, Takeshita Y, Kita Y, Shimizu A, Hayakawa T, Kato K, Kaneko S, Takamura T
- Journal Title
  
  J Diabetes Investig
  
  Volume: 6 Issue: 3 Pages: 346-353
- DOI
  10.1111/jdi.12296
- NAID
  120005819637
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461329, KAKENHI-PROJECT-26253046
[Journal Article] Vildagliptin vs liraglutide as a second-line therapy switched from sitagliptin-based regimens in patients with type 2 diabetes: A randomized, parallel-group study.2015
- Author(s)
  Takeshita Y, Takamura T, Kita Y, Otoda T, Kato K, Wakakuri H, Yamada M, Misu H, Matsushima Y, Kaneko S
- Journal Title
  
  J Diabetes Investig
  
  Volume: 6 Issue: 2 Pages: 192-200
- DOI
  10.1111/jdi.12269
- NAID
  120005774894
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461334, KAKENHI-PROJECT-26461329, KAKENHI-PROJECT-26253046
[Journal Article] Characteristics of hepatic fatty acid compositions in patients with nonalcoholic steatohepatitis.2015
- Author(s)
  Yamada K, Mizukoshi E, Sunagozaka H, Arai K, Yamashita T, Takeshita Y, Misu H, Takamura T, Kitamura S, Zen Y, Nakanuma Y, Honda M, Kaneko S.
- Journal Title
  
  Liver Int.
  
  Volume: 35(2) Issue: 2 Pages: 582-90
- DOI
  10.1111/liv.12685
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390187, KAKENHI-PROJECT-25461334, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-26461329, KAKENHI-PROJECT-15H04809, KAKENHI-PROJECT-26670378
[Journal Article] The effects of ezetimibe on non-alcoholic fatty liver disease and glucose metabolism : a randomised controlled trial2014
- Author(s)
  Takeshita Y, Takamura T, Honda M, Kita Y, Zen Y, Kato KI, Misu H, Ota T, Nakamura M, Yamada K, Sunagozaka H, Arai K, Yamashita T, Mizukoshi E, Kaneko S
- Journal Title
  
  Diabetologia
  
  Volume: 57 Pages: 878-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591301
[Journal Article] Metformin Suppresses Expression of the Selenoprotein P Gene via an AMP-activated Kinase (AMPK)/FoxO3a Pathway in H4IIEC3 Hepatocytes2014
- Author(s)
  Takayama H, Misu H, Iwama H, Chikamoto K, Saito Y, Murao K, Teraguchi A, Lan F, Kikuchi A, Saito R, Tajima N, Shirasaki T, Matsugo S, Miyamoto K, Kaneko S, Takamura T
- Journal Title
  
  J Biol Chem
  
  Volume: 289 Pages: 335-45
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591301
[Journal Article] Metformin Suppresses Expression of the Selenoprotein P gene via an AMPK-FoxO3a Pathway in H4IIEC3 Hepatocytes2014
- Author(s)
  H Takayama, H Misu, H Iwama, K Chikamoto, Y Saito, K Murao, A Teraguchi, F Lan, A Kikuchi, R Saito, N Tajima, T Shirasaki, S Matsugo, KI Miyamoto, S Kaneko, T Takamura
- Journal Title
  
  J Biol Chem
  
  Volume: 289(1) Issue: 1 Pages: 335-45
- DOI
  10.1074/jbc.m113.479386
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249042, KAKENHI-PROJECT-23591301, KAKENHI-PROJECT-24591352, KAKENHI-PROJECT-25461334, KAKENHI-PROJECT-26461329
[Journal Article] LECT2 functions as a hepatokine that links obesity to skeletal muscle insulin resistance2014
- Author(s)
  F Lan, H Misu, K Chikamoto, H Takayama, A Kikuchi, K Mohri, N Takata, H Hayashi, N Matsuzawa-Nagata, Y Takeshita, H Noda, Y Matsumoto, T Ota, T Nagano, M Nakagen, KI Miyamoto, K Takatsuki, T Seo, K Iwayama, K Tokuyama, S Matsugo, H Tang, Y Saito, S Yamagoe, S Kaneko, T Takamura
- Journal Title
  
  Diabetes
  
  Volume: (in press)
- NAID
  120005440333
- Data Source
  KAKENHI-PROJECT-23249042
[Journal Article] Selenoprotein P as a diabetes-associated hepatokine that impairs angiogenesis by inducing VEGF resistance in vascular endothelial cells.2014
- Author(s)
  Ishikura K, Misu H, Kumazaki M, Takayama H, Matsuzawa-Nagata N, Tajima N, Chikamoto K, Lan F, Ando H, Ota T, Sakurai M, Takeshita Y, Kato K, Fujimura A, Miyamoto K, Saito Y, Kameo S, Okamoto Y, Takuwa Y, Takahashi K, Kidoya H, Takakura N, Kaneko S, Takamura T
- Journal Title
  
  Diabetologia
  
  Volume: 57 Issue: 9 Pages: 1968-1976
- DOI
  10.1007/s00125-014-3306-9
- NAID
  120005463349
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22112005, KAKENHI-PROJECT-24390051, KAKENHI-PUBLICLY-25116711, KAKENHI-PUBLICLY-25122710, KAKENHI-PROJECT-25282017, KAKENHI-PROJECT-25292078, KAKENHI-PROJECT-25461334, KAKENHI-PROJECT-25670162, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-26461329
[Journal Article] Remodeling of nutrient homeostasis by unfolded protein response (Commentary)2014
- Author(s)
  Takamura T
- Journal Title
  
  Diabetes
  
  Volume: 63 Pages: 841-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591301
[Journal Article] Remodeling of nutrient homeostasis by unfolded protein response.2014
- Author(s)
  Takamura T
- Journal Title
  
  Diabetes
  
  Volume: 63 Issue: 3 Pages: 841-3
- DOI
  10.2337/db13-1721
- NAID
  120005411651
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591301, KAKENHI-PROJECT-26461329
[Journal Article] Ectopic fat accumulation and distant organ-specific insulin resistance in Japanese people with nonalcoholic Fatty liver disease2014
- Author(s)
  K Kato, T Takamura, Y Takeshita, Y Ryu, H Misu, T Ota, K Tokuyama, S Nagasaka, M Matsuhisa, O Matsui, S Kaneko
- Journal Title
  
  PLoS One
  
  Volume: 9(3) Issue: 3 Pages: e92170-e92170
- DOI
  10.1371/journal.pone.0092170
- NAID
  120005440398
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23249042, KAKENHI-PROJECT-23591301, KAKENHI-PROJECT-25282017, KAKENHI-PROJECT-25461334, KAKENHI-PROJECT-26461329
[Journal Article] The effects of ezetimibe on non-alcoholic fatty liver disease and glucose metabolism : a randomised controlled trial2014
- Author(s)
  Y Takeshita, T Takamura, M Honda, Y Kita, Y Zen, KI Kato, H Misu, T Ota, M Nakamura, K Yamada, H Sunagozaka, K Arai, T Yamashita, E Mizukoshi, S Kaneko
- Journal Title
  
  Diabetologia
  
  Volume: 57(5) Issue: 5 Pages: 878-90
- DOI
  10.1007/s00125-013-3149-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23249042, KAKENHI-PROJECT-23701098, KAKENHI-PROJECT-24390187, KAKENHI-PROJECT-25282017, KAKENHI-PROJECT-25461334, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-26461329, KAKENHI-PROJECT-26670378
[Journal Article] LECT2 functions as a hepatokine that links obesity to skeletal muscle insulin resistance2014
- Author(s)
  Fei Lan, H Misu, K Chikamoto, H Takayam, A Kikuchi, K Mohri, N Takata, H Hayashi, N Matsuzawa-Nagata, Y Takeshita, H Noda, Y Matsumoto, T Ota, T Nagano, M Nakagen, K Miyamoto, K Takatsuki, T Seo, K Iwayama, K Tokuyama, S Matsugo, H Tang, Y Saito, S Yamagoe, S Kaneko, T Takamura
- Journal Title
  
  Diabete
  
  Volume: 63 Issue: 5 Pages: 1649-1664
- DOI
  10.2337/db13-0728
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-14J03079, KAKENHI-PROJECT-23590275, KAKENHI-PROJECT-23591301, KAKENHI-PROJECT-25282017, KAKENHI-PROJECT-25292078, KAKENHI-PROJECT-25461334, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-26461329, KAKENHI-PROJECT-26670229
[Journal Article] LECT2 functions as a hepatokine that links obesity to skeletal muscle insulin resistance2014
- Author(s)
  Lan F, Misu H, Chikamoto K, Takayama H, Kikuchi A, Mohri K, Takata N, Hayashi H, Matsuzawa-Nagata N, Takeshita Y, Noda H, Matsumoto Y, Ota T, Nagano T, Nakagen M, Miyamoto KI, Takatsuki K, Seo T, Iwayama K, Tokuyama K, Matsugo S, Tang H, Saito Y, Yamagoe S, Kaneko S, Takamura T
- Journal Title
  
  Diabetes
  
  Volume: 63 Pages: 1649-64
- NAID
  120005440333
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591301
[Journal Article] Ectopic fat accumulation and distant organ-specific insulin resistance in Japanese people with nonalcoholic Fatty liver disease2014
- Author(s)
  Kato K, Takamura T, Takeshita Y, Ryu Y, Misu H, Ota T, Tokuyama K, Nagasaka S, Matsuhisa M, Matsui O, Kaneko S
- Journal Title
  
  PLOS ONE
  
  Volume: 20;9
- NAID
  120005440398
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591301
[Journal Article] Adipose tissue-derived stem cells as a regenerative therapy for a mouse steatohepatitis-induced cirrhosis model2013
- Author(s)
  A Seki, S Y akai, T Komura, A Nasti, K Yoshida, M Higashimoto, M Honda, S Usui, M Takamura, T Takamura, T Ochiya, K Furuichi, T Wada, S Kaneko
- Journal Title
  
  Hepatology
  
  Volume: 58(3) Issue: 3 Pages: 1133-42
- DOI
  10.1002/hep.26470
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249042, KAKENHI-PROJECT-23590968, KAKENHI-PROJECT-24390187, KAKENHI-PROJECT-24406028, KAKENHI-PROJECT-24591092, KAKENHI-PROJECT-25670269
[Journal Article] Discrete nature of EpCAM(+) and CD90(+) cancer stem cells in human hepatocellular carcinoma.2013
- Author(s)
  Yamashita T, Nakamoto Y, et al.
- Journal Title
  
  Hepatology
  
  Volume: 57 Issue: 4 Pages: 1484-1497
- DOI
  10.1002/hep.26168
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390149, KAKENHI-PROJECT-22590723, KAKENHI-PROJECT-23249042, KAKENHI-PROJECT-23590967, KAKENHI-PROJECT-23659396, KAKENHI-PROJECT-24390187, KAKENHI-PROJECT-24701024, KAKENHI-PROJECT-25293171
[Journal Article] Sugar-sweetened beverage and diet soda consumption and the 7-year risk for type 2 diabetes mellitus in middle-aged Japanese men.2013
- Author(s)
  Sakurai M, Nakamura K, Miura K, Takamura T, Yoshita K, Nagasawa SY, Morikawa Y, Ishizaki M, Kido T, Naruse Y, Suwazono Y, Sasaki S, Nakagawa H.
- Journal Title
  
  Eur J Nutr
  
  Volume: [Epub ahead of print]
- NAID
  120005254069
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591301
[Journal Article] Quantitative analysis of hepatic fat fraction by single-breath-holding MR spectroscopy with T (2) correction: phantom and clinical study with histologic assessment.2013
- Author(s)
  Hayashi N, Miyati T, Minami T, Takeshita Y, Ryu Y, Matsuda T, Ohno N, Hamaguchi T, Kato K, Takamura T, Matsui O.
- Journal Title
  
  Radiol Phys Technol
  
  Volume: 6 Issue: 1 Pages: 219-25
- DOI
  10.1007/s12194-012-0191-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591301
[Journal Article] Proteasome dysfunction mediates obesity-induced endoplasmic reticulum stress and insulin resistance in the liver2013
- Author(s)
  T Otoda, T Takamura, H Misu, T Ota, S Murata, H Hayashi, H Takayama, A Kikuchi, T Kanamori, KR Shima, F Lan, T Takeda, S Kurita, K Ishikura, Y Kita, K Iwayama, KI Kato, M Uno, Y Takeshita, M Yamamoto, K Tokuyama, S Iseki, K Tanaka, S Kaneko
- Journal Title
  
  Diabetes
  
  Volume: 62(3) Issue: 3 Pages: 811-24
- DOI
  10.2337/db11-1652
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249042, KAKENHI-PROJECT-23591301, KAKENHI-PROJECT-23791022, KAKENHI-PROJECT-25282017
[Journal Article] Proteasome Dysfunction Mediates Obesity-Induced Endoplasmic Reticulum Stress and Insulin Resistance in the Liver2013
- Author(s)
  Otoda T, Takamura T, Misu H, Ota T, Murata S, Hayashi H, Takayama H, Kikuchi A, Kanamori T, Shima KR, Lan F, Takeda T, Kurita S, Ishikura K, Kita Y, Iwayama K, Kato KI, Uno M, Takeshita Y, Yamamoto M, Tokuyama K, Iseki S, Tanaka K, Kaneko S
- Journal Title
  
  Diabetes
  
  Volume: 62 Pages: 811-24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591301
[Journal Article] Clinicopathological features of liver injury in patients with type 2 diabetes mellitus and comparative study of histologically proven nonalcoholic fatty liver diseases with or without type 2 diabetes mellitus2013
- Author(s)
  Shima T, Uto H, Ueki K, Takamura T, Kohgo Y, Kawata S, Yasui K, Park H, Nakamura N, Nakatou T, Tanaka N, Umemura A, Mizuno M, Tanaka J, Okanoue T
- Journal Title
  
  J Gastroenterol
  
  Volume: 48 Issue: 4 Pages: 515-525
- DOI
  10.1007/s00535-012-0653-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590470, KAKENHI-PROJECT-23590981, KAKENHI-PROJECT-23591301
[Journal Article] Dosing time-dependent effect of raloxifene on plasma plasminogen activator inhibitor-1 concentrations in post-menopausal women with osteoporosis2013
- Author(s)
  H Ando, T Otoda, H Ookami, Y Nagai, A Inano, T Takamura, K Ushijima, K Hosohata, E Matsushita, T Saito, S Kaneko, A Fujimura
- Journal Title
  
  Clin Exp Pharmacol Physiol
  
  Volume: 40(3) Issue: 3 Pages: 227-32
- DOI
  10.1111/1440-1681.12055
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249042, KAKENHI-PROJECT-23591301, KAKENHI-PROJECT-24790535
[Journal Article] Adipose tissue-derived stem cells as a regenerative therapy for a murine steatohepatitis-induced cirrhosis model2013
- Author(s)
  Seki A, Sakai Y, Komura T, Nasti A, Yoshida K, Higashimoto M, Honda M, Usui S, Takamura M, Takamura T, Ochiya T, Furuichi K, Wada T, Kaneko S
- Journal Title
  
  Hepatology
  
  Volume: 58 Pages: 1133-42
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591301
[Journal Article] CCR5 plays a critical role in obesity-induced adipose tissue inflammation and insulin resistance by regulating both macrophage recruitment and M1/M2 status2012
- Author(s)
  Kitade H, Sawamoto K, Nagashimada M, Inoue H, Yamamoto Y, Sai Y, Takamura T, Yamamoto H, Miyamoto K, Ginsberg HN, Mukaida N, Kaneko S, Ota T
- Journal Title
  
  Diabetes IN PRESS
  
  Volume: 61(7) Issue: 7 Pages: 1680-90
- DOI
  10.2337/db11-1506
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790854, KAKENHI-PROJECT-23249042, KAKENHI-PROJECT-23591301, KAKENHI-PROJECT-23659430
[Journal Article] Metformin prevents and reverses inflammation in a non-diabetic mouse model of nonalcoholic steatohepatitis2012
- Author(s)
  Kita Y, Takamura T, Misu H, Ota T, Kurita S, Takeshita Y, Uno M, Matsuzawa-Nagata N, Kato K, Ando H, Fujimura A, Hayashi K, Kimura T, Ni Y, Otoda T, Miyamoto K, Zen Y, Nakanuma Y, Kaneko S
- Journal Title
  
  PLOS ONE
  
  Volume: 7
- NAID
  120004966626
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591301
[Journal Article] Fatty liver as a consequence and cause of insulin resistance: Lessons from type 2 diabetic liver (Review).2012
- Author(s)
  Takamura T, Misu H, Ota T, Kaneko S.
- Journal Title
  
  Endocr J
  
  Volume: 59 Pages: 745-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591301
[Journal Article] Fatty liver as a consequence and cause of insulin resistance: Lessons from type 2 diabetic liver.2012
- Author(s)
  T Takamura
- Journal Title
  
  Endocr J
  
  Volume: 59 Pages: 745-763
- NAID
  10031123118
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249042
[Journal Article] Duodenal adenocarcinoma with neuroendocrine features in a patient with acromegaly and thyroid papillary adenocarcinoma: a unique combination of endocrine neoplasia.2012
- Author(s)
  Kato K, Takeshita Y, Misu H, Ishikura K, Kakinoki K, Kitamura SS, Kaneko S, Takamura T.
- Journal Title
  
  Endocr J
  
  Volume: 59 Pages: 791-6
- NAID
  10031123122
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591301
[Journal Article] Pharmacokinetics and pharmacodynamics of insulin aspart in patients with Type 2 diabetes : Assessment using a meal tolerance test under clinical conditions2012
- Author(s)
  H Ando, S Kurita, A Shimizu, K Kato, K Ishikura, K Taji, M Uno, Y Takeshita, H Misu, A Fujimura, S Kaneko, T Takamura
- Journal Title
  
  Clin Exp Pharmacol Physiol
  
  Volume: 39(6) Issue: 6 Pages: 528-34
- DOI
  10.1111/j.1440-1681.2012.05708.x
- NAID
  120004442389
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249042, KAKENHI-PROJECT-23791022
[Journal Article] CCR5 plays a critical role in obesity-induced adipose tissue inflammation and insulin resistance by regulating both macrophage recruitment and M1/M2 status2012
- Author(s)
  H Kitade, K Sawamoto, M Nagashimada, H Inoue, Y Yamamoto, Y Sai, T Takamura, H Yamamoto, K Miyamoto, H N. Ginsberg, N Mukaida, S Kaneko, T Ota
- Journal Title
  
  Diabetes
  
  Volume: 61 Pages: 1680-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591301
[Journal Article] Beneficial effect of branched-chain amino acid supplementation on glycemic control in chronic hepatitis C patients with insulin resistance : Implications for type 2 diabetes. Metabolism2012
- Author(s)
  Honda M, (他12名, 12番目)
- Journal Title
  
  Epub ahead of print
  
  Volume: (Epub ahead of print) Issue: 10 Pages: 1388-94
- DOI
  10.1016/j.metabol.2012.03.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390227, KAKENHI-PROJECT-23249042, KAKENHI-PROJECT-23590968, KAKENHI-PROJECT-23591301, KAKENHI-PROJECT-23791022, KAKENHI-PROJECT-24390187
[Journal Article] Dietary glycemic index and risk of type 2 diabetes mellitus in middle-aged Japanese men.2012
- Author(s)
  Sakurai M, Nakamura K, Miura K, Takamura T, Yoshita K, Morikawa Y, Ishizaki M, Kido T, Naruse Y, Suwazono Ybsaki S, Nakagawa H
- Journal Title
  
  Metabolism
  
  Volume: 61 Issue: 1 Pages: 47-55
- DOI
  10.1016/j.metabol.2011.05.015
- NAID
  120003752530
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591301
[Journal Article] Synthesis, Structure, and Physiological Effects of Peroxovanadium(V) Complexes Containing Amino Acid Derivatives as Ancillary Ligands.2012
- Author(s)
  Sugiyama H, Matsugo S, Konish T, Takamura T, Kaneko S, Kubo Y, Sato K, Kanamori K.
- Journal Title
  
  Chem Lett
  
  Volume: 41 Pages: 377-379
- DOI
  10.1016/j.jinorgbio.2012.12.014
- NAID
  10030544514
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591301
[Journal Article] Inverse correlation between serum levels of selenoprotein P and adiponectin in patients with type 2 diabetes2012
- Author(s)
  H Misu, K Ishikura, S Kurita, Y Takeshita, T Ota, Y Saito, K Takahashi, S Kaneko, T Takamura
- Journal Title
  
  PLoS One
  
  Volume: 7(4) Issue: 4 Pages: e34952-e34952
- DOI
  10.1371/journal.pone.0034952
- NAID
  120004140847
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249042, KAKENHI-PROJECT-23591301, KAKENHI-PROJECT-23791022
[Journal Article] Metformin prevents and reverses inflammation in a non-diabetic mouse model of nonalcoholic steatohepatitis2012
- Author(s)
  Y Kita, T Takamura, H Misu, T Ota, S Kurita, Y Takeshita, M Uno, N Matsuzawa-Nagata, K Kato, H Ando, A Fujimura, K Hayashi, T Kimura, Y Ni, T Otoda, K Miyamoto, Y Zen, Y Nakanuma, S Kaneko
- Journal Title
  
  PLoS One
  
  Volume: 7(9) Issue: 9 Pages: e43056-e43056
- DOI
  10.1371/journal.pone.0043056
- NAID
  120004966626
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249042, KAKENHI-PROJECT-23591301, KAKENHI-PROJECT-23791022
[Journal Article] Genetic polymorphisms of the human PNPLA3 gene are strongly associated with severity of non-alcoholic fatty liver disease in Japanese.2012
- Author(s)
  Kawaguchi T
- Journal Title
  
  PLoS One
  
  Volume: 7 Issue: 6 Pages: e38322-e38322
- DOI
  10.1371/journal.pone.0038322
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23221005, KAKENHI-PROJECT-23590379, KAKENHI-PROJECT-23590470, KAKENHI-PROJECT-23591301, KAKENHI-PROJECT-24590981
[Journal Article] Dietary glycemic index and risk of type 2 diabetes in middle-aged Japanese men2012
- Author(s)
  M Sakurai, K Nakamura, K Miura, T Takamura, K Yoshita, Y Morikawa, M Ishizaki, T Kido, Y Naruse, Y Suwazono, S Kaneko, S Sasaki, H Nakagawa
- Journal Title
  
  Metabolism
  
  Volume: 61(1) Issue: 12 Pages: 47-55
- DOI
  10.1016/j.jada.2010.09.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249042
[Journal Article] Fatty liver as a consequence and cause of insulin resistance : Lessons from type 2 diabetic liver (Review)2012
- Author(s)
  Takamura T, Misu H, Ota T, Kaneko S
- Journal Title
  
  Endocr J
  
  Volume: 59 Pages: 745-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591301
[Journal Article] Inverse Correlation between Serum Levels of Selenoprotein P and Adiponectin in Patients with Type 2 Diabetes2012
- Author(s)
  Misu H, Ishikura K, Kurita S, Takeshita Y, Ota T, Saito Y, Takahashi K, Kaneko S, Takamura T
- Journal Title
  
  PLOS ONE
  
  Volume: 7
- NAID
  120004140847
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591301
[Journal Article] Self-reported speed of eating and 7-year risk of type 2 diabetes mellitus in middle-aged Japanese men.2012
- Author(s)
  Sakurai M, Nakamura K, Miura K, Takamura T, Yoshita K, Nagasawa SY, Morikawa Y, Ishizaki M, Kido T, Naruse Y, Suwazono Y, Sasaki S, Nakagawa H.
- Journal Title
  
  Metabolism
  
  Volume: 61 Issue: 11 Pages: 1566-71
- DOI
  10.1016/j.metabol.2012.04.005
- NAID
  120004997012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591301
[Journal Article] Identification of blood biomarkers of aging by transcript profiling of whole blood2012
- Author(s)
  Honda M, (他7名, 4番目)
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 418(2) Issue: 2 Pages: 313-8
- DOI
  10.1016/j.bbrc.2012.01.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390227, KAKENHI-PROJECT-23591301
[Journal Article] Fatty liver as a consequence and cause of insulin resistance : Lessons from type 2 diabetic liver2012
- Author(s)
  T Takamura, H Misu, T Ota, S Kaneko
- Journal Title
  
  Endocr J
  
  Volume: 59(9) Pages: 745-63
- NAID
  10031123118
- Data Source
  KAKENHI-PROJECT-23249042
[Journal Article] Identification of blood biomarkers of aging by transcript profiling of whole blood2012
- Author(s)
  Nakamura S, Kawai K, Takeshita Y, Honda M, Takamura T, Kaneko S, Matoba R, Matsubara K
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 418 Pages: 313-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591301
[Journal Article] Japan NASH Study Group, Ministry of Health, Labour, and Welfare of Japan : Characteristics of patients with nonalcoholic steatohepatitis who develop hepatocellular carcinoma2011
- Author(s)
  Yasui K, Hashimoto E, Komorizono Y, Saibara T
- Journal Title
  
  Clin Gastroenterol Hepatol
  
  Volume: 9 Issue: 5 Pages: 428-433
- DOI
  10.1016/j.cgh.2011.01.023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590849, KAKENHI-PROJECT-23590470, KAKENHI-PROJECT-23590981, KAKENHI-PROJECT-23591301
[Journal Article] Association between coefficients of variation of the R-R intervals on electrocardiograms and post-challenge hyperglycemia in patients with newly diagnosed type 2 diabetes2011
- Author(s)
  Nakade Y, Takamura T, Sakurai M, Misu H, Nagata M, Nanbu Y, Oe H, Takamura T, Sakai Y, Kaneko S, Wada T
- Journal Title
  
  J Diabetes Invest
  
  Volume: 2 Issue: 4 Pages: 324-327
- DOI
  10.1111/j.2040-1124.2010.00098.x
- NAID
  120005373517
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591301
[Journal Article] Dose-dependent Dual Effects of Hydrogen Peroxide on Insulin Signal Transduction in H4IIEC Hepatocytes.2011
- Author(s)
  Iwakami S, Misu H, Takeda T, Sugimori M, Matsugo S, Kaneko S, Takamura T
- Journal Title
  
  PLoS ONE
  
  Volume: 6 Issue: 11 Pages: e27401-e27401
- DOI
  10.1371/journal.pone.0027401
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591301, KAKENHI-PROJECT-23791022
[Journal Article] Concentration-dependent dual effects of hydrogen peroxide on insulin signal transduction in H4IIEC hepatocytes2011
- Author(s)
  Iwakami S, Misu H, Takeda T, Sugimori M, Matsugo S, Kaneko S, Takamura T
- Journal Title
  
  PLOS ONE
  
  Volume: 6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591301
[Journal Article] CD14+ monocytes are vulnerable and functionally impaired under endoplasmic reticulum stress in patients with type 2 diabetes.2010
- Author(s)
  Komura T, Sakai Y, Honda M, Takamura T, Matsushima K, Kaneko S
- Journal Title
  
  Diabetes 59
  
  Pages: 634-643
- NAID
  120002104558
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article] CD14+monocytes are vulnerable and functionally impaired under ER stress in patients with type 2 diabetes.2010
- Author(s)
  Komura T, Sakai Y, Honda M, Takamura T, Matsushima K, Kaneko S
- Journal Title
  
  Diabetes 59
  
  Pages: 634-643
- NAID
  120002104558
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article] A liver-derived secretory protein, selenoprotein P, causes insulin resistance.2010
- Author(s)
  H Misu, T Takamura, H Takayama, H Hayashi, N Matsuzawa-Nagata, S Kurita, K Ishikura, H Ando, Y Takeshita, T Ota, M Sakurai, T Yamashita, E Mizukoshi, T Yamashita, M Honda, K Miyamoto, T Kubota, N Kubota, T Kadowaki, HJ Kim, IK Lee, Y Minokoshi, Y Saito, K Takahashi, Y Yamada, N Takakura, S Kaneko.
- Journal Title
  
  Cell Metab 12(5)
  
  Pages: 483-495
- NAID
  120002661942
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Histological course of nonalcoholic fatty liver disease in Japanese patients : tight glycemic control, rather than weight reduction, ameliorates liver fibrosis.2010
- Author(s)
  Hamaguchi E, Takamura T, et al.
- Journal Title
  
  Diabetes Care 33
  
  Pages: 284-286
- NAID
  120001938902
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article] Altered hepatic gene expression profiles associated with myocardial ischemia.2010
- Author(s)
  Ootsuji H, Honda M, Kaneko S, Usui S, Okajima M, Okada H, Sakai Y, Takamura T, et al.
- Journal Title
  
  Circ Cardiovasc Genet 3
  
  Pages: 68-77
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article] Aliver-derived secretory protein, selenoprotein p, causes insulin resistance.2010
- Author(s)
  Misu H, Takamura T, Takayama H, Hayashi H, Matsuzawa-Nagata N, Kurita S, Ishikura K, Ando H, Takeshita Y, Ota T, Sakurai M, Yamashita T, Mizukoshi E, Honda M, Miyamoto K, Kubota T, Kubota N, KadowakiT, Kim HJ, Lee IK, Minokoshi Y, Saito Y, TakahashiK, Yamada Y, Takakura NKaneko S
- Journal Title
  
  Cell Metab
  
  Volume: 12 Pages: 483-495
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article] Associations of metabolic parameters and ethanol consumption with messenger RNA expression of clock genes in healthy men.2010
- Author(s)
  Ando H, Ushijima K, Kumazaki M, Eto T, Takamura T, Irie S, Kaneko S, Fujimura A
- Journal Title
  
  Chronobiol Int 27
  
  Pages: 194-203
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article] CD14+monocytes are vulnerable and functionally impaired under ER stress in patients with type 2 diabetes.2010
- Author(s)
  T Komura, Y Sakai, M Honda, T Takamura, K Matsushima, S Kaneko.
- Journal Title
  
  Diabetes 59(3)
  
  Pages: 634-643
- NAID
  120002104558
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Oncostatin m renders epithelial cell adhesion molecule-positive liver cancer stem cells sensitive to 5-Fluorouracil by inducing hepatocytic differentiation.2010
- Author(s)
  T Yamashita, M Honda, K Nio, Y Nakamoto, T Yamashita, H Takamura, T Tani, Y Zen, S Kaneko.
- Journal Title
  
  Cancer Res 70(11)
  
  Pages: 4687-4697
- NAID
  120002220837
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Influence of age on clock gene expression in peripheral blood cells of healthy women.2010
- Author(s)
  Ando H, Ushijima K, Kumazaki M, Takamura T, Yokota N, Saito T, Irie S, Kaneko S, Fujimura A
- Journal Title
  
  J Gerontol A Biol Sci Med Sci 65
  
  Pages: 9-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article] Altered hepatic gene expression profiles associated with myocardial ischemia.2010
- Author(s)
  Ootsuji H, Honda M, Kaneko S, Usui S, Okajima M, Okada H, Sakai Y, Takamura T, Horimoto K, Takamura M
- Journal Title
  
  Circ Cardiovasc Genet
  
  Volume: 3 Pages: 68-77
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article] Influence of age on clock gene expression in peripheral blood cells of healthy women.2010
- Author(s)
  Ando H, Ushijima K, Kumazaki M, Takamura T, Yokota N, Saito T, Irie S, Kaneko S, Fujimura A
- Journal Title
  
  J Gerontol A Biol Sci Med Sci
  
  Volume: 65 Pages: 9-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article]2010
- Author(s)
  篁俊成
- Journal Title
  
  糖尿病性ケトアシドーシス・高血糖高浸透圧症候群.「栄養塾-症例で学ぶクリニカルパール」(医学書院)
  
  Pages: 232-238
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article] Histological course of nonalcoholic fatty liver disease in Japanese patients : tight glycemic control, rather than weight reduction, ameliorates liver fibrosis.:, 20102010
- Author(s)
  Hamaguchi E, Takamura T, Sakurai M, Mizukoshi E, Zen Y, Takeshita Y, Kurita S, Arai K, Yamashita T, Sasaki M, Nakanuma Y, Kaneko S
- Journal Title
  
  Diabetes Care 33
  
  Pages: 284-286
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article] Altered hepatic gene expression profiles associated with myocardial ischemia.2010
- Author(s)
  H Ootsuji, M Honda, S Kaneko, S Usui, M Okajima, H Okada, Y Sakai, T Takamura, K Horimoto, M Takamura.
- Journal Title
  
  Circ Cardiovasc Genet 3(1)
  
  Pages: 68-77
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Altered hepatic gene expression profiles associated with myocardial ischemia.2010
- Author(s)
  Ootsuji H, Honda M, Kaneko S, Usui S, Okajima M, Okada H, Sakai Y, Takamura T, Horimoto K, Takamura M
- Journal Title
  
  Circ Cardiovasc Genet 3
  
  Pages: 68-77
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article] The histological course of nonalcoholic fatty liver disease in Japanese patients : Tight glycemic control, rather than weight reduction, ameliorates liver fibrosis.2010
- Author(s)
  E Hamaguchi, T Takamura, M Sakurai, E Mizukoshi, Y Zen, Y Takeshita, S Kurita, K Arai, T Yamashita, M Sasaki, Y Nakanuma, S Kaneko.
- Journal Title
  
  Diabetes Care 33(2)
  
  Pages: 284-286
- NAID
  120001938902
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] CD14+ monocytes are vulnerable and functionally impaired under endoplasmic reticulum stress in patients with type 2 diabetes.2010
- Author(s)
  Komura T, Sakai Y, HondaM, Takamura T, Matsushima K, Kaneko S
- Journal Title
  
  Diabetes
  
  Volume: 59 Pages: 634-643
- NAID
  120002104558
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article] A liver-derived secretory protein, selenoprotein p, causes insulin resistance.2010
- Author(s)
  Misu H, Takamura T, et al.
- Journal Title
  
  Cell Metab 12
  
  Pages: 483-495
- NAID
  120002661942
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article] Associations of metabolic parameters and ethanol consumption with messenger RNA expression of clock genes in healthy men.2010
- Author(s)
  Ando H, Ushijima K, Kumazaki M, Eto T, Takamura T, Irie S, Kaneko S, Fujimura A
- Journal Title
  
  Chronobiol Int
  
  Volume: 27 Pages: 194-203
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article] Histological course of nonalcoholic fatty liver disease in Japanese patients : tight glycemic control, rather than weight reduction, ameliorates liver fibrosis.2010
- Author(s)
  Hamaguchi E, Takamura T, Sakurai M, Mizukoshi E, ZenY, Takeshita Y, Kurita S, AraiK, Yamashita T, Sasaki M, Nakanuma Y, Kaneko S
- Journal Title
  
  Diabetes Care
  
  Volume: 33 Pages: 284-286
- NAID
  120001938902
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article]2009
- Author(s)
  篁俊成, 金子周一
- Journal Title
  
  代謝臓器としての肝臓の分子生物学.「Annual Review消化器2009」(林紀夫, 日比紀文, 上西紀夫, 下瀬川徹編)(中外医学社)
  
  Pages: 148-156
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article] The hepatic circadian clock is preserved in a lipid-induced mouse model of non-alcoholic steatohepatitis2009
- Author(s)
  Ando H, Takamura T, Matsuzawa-Nagata N, Shima KR, Nakamura S, Kumazaki M, Kurita S, Misu H, Togawa N, Fukushima T, Fujimura A, Kaneko S
- Journal Title
  
  Biochem Biophys Res Commun 380
  
  Pages: 684-688
- NAID
  120001170074
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article] Clock gene expression in the liver and adipose tissues of non-obese type 2 diabetic Goto-Kakizaki rats.2009
- Author(s)
  Ando H, Ushijima K, Yanagihara H, Hayashi Y, Takamura T, et al.
- Journal Title
  
  Clin Exp Hypertens 31
  
  Pages: 201-207
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article] The hepatic circadian clock is preserved in a lipid-induced mouse model of non-alcoholic steatohepatitis.2009
- Author(s)
  Ando H, Takamura T, Matsuzawa-Nagata N, Shima KR, Nakamura S, Kumazaki M, Kurita S, Misu H, Togawa N, Fukushima T, Fujimura A, Kaneko S
- Journal Title
  
  Biochem Biophys Res Commun 380
  
  Pages: 684-688
- NAID
  120001170074
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article] Middle-aged Japanese women are resistant to obesity-related metabolic abnormalities.2009
- Author(s)
  Sakurai M, Takamura T, Miura K, Kaneko S, Nakagawa H
- Journal Title
  
  Metabolism 58
  
  Pages: 456-459
- NAID
  120001249808
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article]2009
- Author(s)
  篁俊成
- Journal Title
  
  内分泌・代謝系糖尿病治療薬.ナーシングムック56「みてわかる薬の作用メカニズム&服薬指導」(藤村昭夫編)(学研メディカル秀潤社)
  
  Pages: 126-131
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article]2009
- Author(s)
  御簾博文, 篁俊成
- Journal Title
  
  活性酸素がインスリンシグナル伝達に与える影響とその二面性.,「病態解明に迫る活性酸素シグナルと酸化ストレス-癌、神経変性疾患、循環・代謝異常にかかわるレドックス制御機構と最新の技術開発-」(谷口直之, 赤池孝章, 鈴木敬一郎, 内田浩二編)(羊土社)
  
  Pages: 212-7
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article] J-shaped relationship between waist circumference and subsequent risk for Type 2 diabetes : an 8-year follow-up of relatively lean Japanese individuals.2009
- Author(s)
  M Sakurai, K Miura, T Takamura, M Ishizaki, Y Morikawa, K Nakamura, K Yoshita, T Kido, Y Naruse, S Kaneko, H Nakagawa.
- Journal Title
  
  Diabet Med 26(8)
  
  Pages: 753-759
- NAID
  120001507851
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Clock gene expression in peripheral leucocytes of patients with type 2 diabetes.2009
- Author(s)
  Ando H, Takamura T, et al.
- Journal Title
  
  Diabetologia 52
  
  Pages: 329-335
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article] Palmitate Induces Insulin Resistance in H4IIEC3 Hepatocytes through Reactive Oxygen Species Produced by Mitochondria.2009
- Author(s)
  S Nakamura, T Takamura, N Matsuzawa-Nagata, H Takayama, H Misu, H Noda, S Nabemoto, S Kurita, T Ota, H Ando, K Miyamoto, S Kaneko.
- Journal Title
  
  J Biol Chem 284(22)
  
  Pages: 14809-14818
- NAID
  120002829203
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Abnormal liver function tests and metabolic syndrome-is fatty liver related to risks for atherosclerosis beyond obesity?2009
- Author(s)
  Sakurai M, Takamura T, Miura K, Kaneko S, Nakagawa H
- Journal Title
  
  Intern Med 48
  
  Pages: 1573-1574
- NAID
  130000122065
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article] J-shaped relationship between waist circumference and subsequent risk for Type 2 diabetes : an 8-year follow-up of relatively lean Japanese individuals.2009
- Author(s)
  Sakurai M, Miura K, Takamura T, Ishizaki M, Morikawa Y, Nakamura K, Yoshita K, Kido T, Naruse Y, Kaneko S, Nakagawa H
- Journal Title
  
  Diabet Med 26
  
  Pages: 753-759
- NAID
  120001507851
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article] Clock gene expression in peripheral leucocytes of patients with type 2 diabetes2009
- Author(s)
  Ando H, Takamura T, Matsuzawa-Nagata N, Shima KR, Eto T, Misu H, Shiramoto M, Tsuru T, Irie S, Fujimura A, Kaneko S
- Journal Title
  
  Diabetologia 52
  
  Pages: 329-335
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article] 肝臓由来分泌タンパク質 "ヘパトカイン"を標的とした2型糖尿病に対する新規治療法の開発2009
- Author(s)
  御簾博文, 篁俊成
- Journal Title
  
  化学工業 59
  
  Pages: 37-42
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article] Activation of lipogenic pathway correlates with cell proliferation and poor prognosis in hepatocellular carcinoma.2009
- Author(s)
  T Yamashita, M Honda, H Takatori, R Nishino, H Minato, H Takamura, T Ohta, S Kaneko.
- Journal Title
  
  J Hepatology 50(1)
  
  Pages: 100-110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Clock gene expression in peripheral leucocytes of patients with type 2 diabetes.2009
- Author(s)
  H Ando, T Takamura, N Matsuzawa-Nagata, KR Shima, T Eto, H Misu, M Shiramoto, T Tsuru, S Irie, A Fujimura, S Kaneko.
- Journal Title
  
  Diabetologia 52(2)
  
  Pages: 329-335
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article]2009
- Author(s)
  櫻井千佳, 篁俊成
- Journal Title
  
  肝疾患合併時.「糖尿病最新の治療2010-2012」(河盛隆造、岩本安彦編)(南江堂)
  
  Pages: 98-98
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article] Clock gene expression in peripheral leucocytes of patients with type 2 diabetes.2009
- Author(s)
  Ando H, Takamura T, Matsuzawa-Nagata N, Shima KR, Eto T, Misu H, Shiramoto M, Tsuru T, Irie S, Fujimura A, Kaneko S
- Journal Title
  
  Diabetologia 52
  
  Pages: 329-335
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article] Palmitate induces insulin resistance in H4IIEC3 hepatocytes through reactive oxygen species produced by mitochondria.2009
- Author(s)
  Nakamura S, Takamura T, Matsuzawa-Nagata N, Takayama H, Misu H, Noda H, Nabemoto S, Kurita S, Ota T, Ando H, Miyamoto K, Kaneko S
- Journal Title
  
  J Biol Chem 284
  
  Pages: 14809-14818
- NAID
  120002829203
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article] Clock gene expression in the liver and adipose tissues of non-obese type 2 diabetic Goto-Kakizaki rats.2009
- Author(s)
  Ando H, Ushijima K, Yanagihara H, Hayashi Y, Takamura T, Kaneko S, Fujimura A
- Journal Title
  
  Clin Exp Hypertens 31
  
  Pages: 201-207
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article] Middle-aged Japanese women are resistant to obesity-related metabolic abnormalities.2009
- Author(s)
  M Sakurai, T Takamura, K Miura, S Kaneko, H Nakagawa.
- Journal Title
  
  Metabolism 58(4)
  
  Pages: 456-459
- NAID
  120001249808
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Palmitate induces insulin resistance in H4IIEC3 hepatocytes through reactive oxygen species produced by mitochondria.2009
- Author(s)
  Nakamura S, Takamura T, et al.
- Journal Title
  
  J Biol Chem 284
  
  Pages: 14809-14818
- NAID
  120002829203
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article] The hepatic circadian clock is preserved in a lipid-induced mouse model of non-alcoholic steatohepatitis.2009
- Author(s)
  Ando H, Takamura T, et al.
- Journal Title
  
  Biochem Biophys Res Commun 380
  
  Pages: 684-688
- NAID
  120001170074
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article] The hepatic circadian clock is preserved in a lipid-induced mouse model of non-alcoholic steatohepatitis.2009
- Author(s)
  H Ando, T Takamura, N Matsuzawa-Nagata, KR Shima, S Nakamura, M Kumazaki, S Kurita, H Misu, N Togawa, T Fukushima, A Fujimura, S Kaneko.
- Journal Title
  
  Biochem Biophys Res Commun 380(3)
  
  Pages: 684-688
- NAID
  120001170074
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] SAGE application in the study of diabetes.2008
- Author(s)
  T Takamura
- Journal Title
  
  Curr Pharm Biotechnol 9
  
  Pages: 392-399
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] ケースバイケースで適したインスリン導入法を考える2008
- Author(s)
  岩本安彦, 番度行弘, 小林正, 浦風雅春, 古家大祐, 篁俊成
- Journal Title
  
  Pharma Medica 25
  
  Pages: 113-115
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article] 新時代の糖尿病学(2)-病因・診断・治療研究の進歩-2008
- Author(s)
  篁俊成
- Journal Title
  
  日本臨床 66
  
  Pages: 33-37
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article] BMI may be better than waist circumference for defining metabolic syndrome in Japanese women.2008
- Author(s)
  M Sakurai, T Takamura, K Miura, S Kaneko, H Nakagawa.
- Journal Title
  
  Diabetes Care 31(3)
  
  Pages: 12-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Obesity Upregulates Genes Involved in Oxidative Phosphorylation in Livers of Diabetic Patients.2008
- Author(s)
  Takamura T, et al.
- Journal Title
  
  Obesity (Silver Spring)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article] Transformation of p53-positive papillary thyroid carcinoma to anaplastic carcinoma of the liver following post operative radioactive iodine-131 therapy2008
- Author(s)
  Takeshita Y, Takamura T, Minato H, Misu H, Ando H, Yamashita T, Ikeda H, Nakanuma Y, Kaneko S
- Journal Title
  
  Intern Med 47
  
  Pages: 1709-1712
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article] Olmesartan ameliorates a dietary rat model of non-alcoholic steatohepatitis through its pleiotropic effects.2008
- Author(s)
  Kurita S, Takamura T, et al.
- Journal Title
  
  Eur J Pharmacol 588
  
  Pages: 316-324
- NAID
  120001130222
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article] 1型糖尿病とバセドウ病を同時期に診断しえた多腺性自己免疫症候群の2例2008
- Author(s)
  乙田敏城, 櫻井勝, 太田嗣人, 栗田征一郎, 御簾博文, 清水暁子, 安藤仁, 金子周一, 篁俊成
- Journal Title
  
  日本糖尿病学会 51
  
  Pages: 323-327
- NAID
  10021275076
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article] BMI may be better than waist circumference for defining metabolic syndrome in Japanese women.2008
- Author(s)
  Sakurai M, Takamura T, et al.
- Journal Title
  
  Diabetes Care 31
  
  Pages: 12-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article] Obesity upregulates genes involved in oxidative phosphorylation in livers of diabetic patients2008
- Author(s)
  T Takamura, H Misu, N Matsuzawa-Nagata, M Sakurai, T Ota, A Shimizu, S Kurita, Y Takeshita, H Ando, M Honda, S Kaneko
- Journal Title
  
  Obesity 16(12)
  
  Pages: 2061-2609
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] 糖質代謝異常2008
- Author(s)
  篁俊成
- Journal Title
  
  日本臨床 66
  
  Pages: 33-37
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article] Influence of physician specialty on treatment goals for diabetic patients : results of a survey given to the members of the Ishikawa medical association2008
- Author(s)
  Koizumi J, Matsukura T, Oyama O, Maeda T, Nomura H, Asano A, Kitatani M, Takamura T, Kondou K
- Journal Title
  
  General Medicine 9
  
  Pages: 71-79
- NAID
  10029403685
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article] Tranilast, an antifibrogenic agent, ameliorates a dietary rat model of nonalcoholic steatohepatitis.2008
- Author(s)
  Uno M, Kurita S, Misu H, Ando H, Ota T, Matsuzawa-Nagata N, Kita Y, Nabemoto S, Akahori H, Zen Y, Nakanuma Y, Kaneko S, Takamura T
- Journal Title
  
  Hepatology 48
  
  Pages: 109-118
- NAID
  120001130339
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article] Olmesartan ameliorates a dietary rat model of non-alcoholic steatohepatitis through its pie iotropic effects2008
- Author(s)
  Kurita S, Takamura T, Ota T, Matsuzawa-Nagata N, Kita Y, Uno M, Nabemoto S, Ishikura K, Misu H, Ando H, Zen Y, Nakanuma Y, Kaneko S
- Journal Title
  
  Eur J Pharmacol 588
  
  Pages: 316-324
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article] Intra-thyroid blood flow in Plummer's disease2008
- Author(s)
  Kurita S, Ando H, Kaneko S, Takamura T
- Journal Title
  
  Intern Med 47
  
  Pages: 1065-1066
- NAID
  130000078670
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article] Cross talk of tumor necrosis factor-alpha and the renin-angiotensin system in tumor necrosis factor-alpha-induced plasminogen activator inhibitor-1production from hepatocytes.2008
- Author(s)
  Takeshita Y, Takamura T, et al.
- Journal Title
  
  Eur J Pharmacol 579
  
  Pages: 426-432
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article] BMI may be better than waist circumference for definingmetabolic syndrome in Japanese women2008
- Author(s)
  Sakurai M, Takamura T, Miura K, Kaneko S, Nakagawa H
- Journal Title
  
  Diabetes Care 31
  
  Pages: 12-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article] 脂肪肝とリポトキシシティ2008
- Author(s)
  太田嗣人, 篁俊成
- Journal Title
  
  The Lipid 19
  
  Pages: 20-26
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article] SAGE application in the study of diabetes.2008
- Author(s)
  T Takamura, H Misu, T Yamashita, S Kaneko.
- Journal Title
  
  Curr Pharm Biotechnol 9(5)
  
  Pages: 392-399
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Obesity Upregulates Genes Involved in Oxidative Phospho rylation in Livers of Diabetic Patients2008
- Author(s)
  Takamura T, Misu H, Matsuzawa-Nagata N, Sakurai M, Ota T, Shimizu A, Kurita S, Takeshita Y, Ando H, Honda M, Kaneko S
- Journal Title
  
  Obesity (Silver Spring) 16
  
  Pages: 2601-2609
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article] Increased oxidative stress precedes the onset of high-fat diet-induced insulin resistance and obesity.2008
- Author(s)
  Matsuzawa-Nagata N, Takamura T, et al.
- Journal Title
  
  Metabolism 57
  
  Pages: 1071-1077
- NAID
  120001130340
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article] SAGE application in the study of diabetes2008
- Author(s)
  Takamura T, Misu H, Yamashi ta T, Kaneko S
- Journal Title
  
  Curr Pharm Biotechnol 9
  
  Pages: 392-399
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article] Increased oxidative stress precedes the onset of high-fat diet-induced insulin resistance and obesity.2008
- Author(s)
  N Matsuzawa-Nagata, T Takamura, H Ando, S Nakamura, S Kurita, H Misu, T Ota, M Yokoyama, M Honda, K Miyamoto, S Kaneko.
- Journal Title
  
  Metabolism 57(8)
  
  Pages: 1071-1077
- NAID
  120001130340
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Tranilast, an antifibrogenic agent, ameliorates a dietary rat model of nonalcoholic steatohepatitis.2008
- Author(s)
  M Uno, S Kurita, H Misu, H Ando, T Ota, N Matsuzawa-Nagata, Y Kita, S Nabemoto, H Akahori, Y Zen, Y Nakanuma, S Kaneko, T Takamura.
- Journal Title
  
  Hepatology 48(1)
  
  Pages: 109-118
- NAID
  120001130339
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] New insulin sensitivity index from the oral glucose tolerance test.2008
- Author(s)
  Kazama Y, Takamura T, et al.
- Journal Title
  
  Diabetes Res Clin Pract 79
  
  Pages: 24-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article] Tranilast, an antifibrogenic agent, ameliorates a dietary rat model of nonalcoholic steatohepatitis2008
- Author(s)
  Uno M, Kurita S, Misu H, Ando H, Ota T, Matsuzawa-Nagata N, Kita Y, Nabemoto S, Akahori H, Zen Y, Nakanuma Y, Kaneko S, Takamura T
- Journal Title
  
  Hepatology 48
  
  Pages: 109-118
- NAID
  120001130339
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article] Obesity upregulates genes involved in oxidative phosphorylation in livers of diabetic patients.2008
- Author(s)
  T Takamura
- Journal Title
  
  Obesity 16
  
  Pages: 2601-2609
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] 肝臓のトランスクリプトームからみた糖尿病2008
- Author(s)
  篁俊成, 安藤仁, 御簾博文, 金子周一
- Journal Title
  
  糖尿病合併症 22
  
  Pages: 136-140
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article] Olmesartan ameliorates a dietary rat model of non-alcoholic steatohepatitis through its pleiotropic effects.2008
- Author(s)
  S Kurita, T Takamura, T Ota, N Matsuzawa-Nagata, Y Kita, M Uno, S Nabemoto, K Ishikura, H Misu, H Ando, Y Zen, Y Nakanuma, S Kaneko.
- Journal Title
  
  Eur J Pharmacol 588(2-3)
  
  Pages: 316-324
- NAID
  120001130222
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Cross talk of tumor necrosis factor-alpha and the renin-angiotensin system in tumor necrosis factor-alpha-induced plasminogen activator inhibitor-1 production from hepatocytes.2008
- Author(s)
  Y Takeshita, T Takamura, H Ando, E Hamaguchi, A Takazakura, N Matsuzawa-Nagata, S Kaneko.
- Journal Title
  
  Eur J Pharmacol 579(1-3)
  
  Pages: 426-432
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] 肥満患者にインスリン療法を導入すべきか?2008
- Author(s)
  加藤健一郎, 安藤仁, 清水暁子, 篁俊成
- Journal Title
  
  Progress in Medicine 28
  
  Pages: 349-352
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article] Obesity upregulates genes involved in oxidative phosphorylation in livers of diabetic patients.2008
- Author(s)
  T Takamura, H Misu, N Matsuzawa-Nagata, M Sakurai, T Ota, A Shimizu, S Kurita, Y Takeshita, H Ando, M Honda, S Kaneko.
- Journal Title
  
  Obesity (Silver Spring) 16(12)
  
  Pages: 2601-2609
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] スルホニル尿素薬とαグルコシダーゼ阻害薬2008
- Author(s)
  御簾博文, 篁俊成
- Journal Title
  
  日本臨床 66
  
  Pages: 305-310
- Data Source
  KAKENHI-PROJECT-20591054
[Journal Article] Impact of diabetes mellitus on prognosis of patients infected with hepatitis C virus.2007
- Author(s)
  Y Kita, E Mizukoshi, T Takamura, M Sakurai, Y Takata, K Arai, T Yamashita, Y Nakamoto, S Kaneko.
- Journal Title
  
  Metabolism 56(12)
  
  Pages: 1682-1288
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Selective estrogen receptor modulator raloxifene-associated aggravaticn of nonalcoholic steatohepatitis2007
- Author(s)
  T Takamura
- Journal Title
  
  Intern Med 46
  
  Pages: 579-581
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Induction of reactive oxygen species from isolated rat glomeruli by protein kinase C activation and TNF-alpha stimulation, and effects of a phosphodiesterase inhibitor2007
- Author(s)
  Koike N.Takamura T.Kaneko S
- Journal Title
  
  Life Sci 80
  
  Pages: 1721-1728
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590920
[Journal Article] Association of the C825T polymorphism of the G-protein β3 subunit gene with hypertension, obesity, hyperlipidemia, insulin resistance, diabetes, diabetic complications, and diabetic therapies among Japanese.2007
- Author(s)
  T Hayakawa, T Takamura, T Abe, SKaneko.
- Journal Title
  
  Metabolism 56(1)
  
  Pages: 44-48
- NAID
  120000809436
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Factors associated with improvement of fasting plasma glucose level by mealtime dosing of a rapid-acting insulin analog in type 2 diabetes.2007
- Author(s)
  T Takamura
- Journal Title
  
  Diabetes Res Clin Pract 75・3
  
  Pages: 278-284
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Liver steatosis, but not fibrosis, is associated with insulin resistance in nonalcoholic fatty liver disease2007
- Author(s)
  Sakurai M, Takamura T, Ota T, Ando H, Akahori H, Kaji K, Sasaki M. Nakanuma Y. Miura K. Kaneko S
- Journal Title
  
  J Gastroenterol 42
  
  Pages: 312-317
- NAID
  10019483538
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590920
[Journal Article] (2006) Management of hyperglycaemia in type 2 diabetes : a consensus algorithm for the initiation and adjustment of therapy. A consensus statement from the American Diabetes Association and the European Association for the Study of2007
- Author(s)
  Comment on: Nathan DM, Buse JB, Davidson MB et al.Takamura T, Shimizu A, Ando H, Kaneko S
- Journal Title
  
  Diabetes. DiabetologiaDiabetologia 49 50
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590920
[Journal Article] Insulin resistance accelerates a dietary rat model of nonalcoholic steatohepatitis.2007
- Author(s)
  T Ota, T Takamura, S Kurita, N Matsuzawa, Y Kita, M Uno, H Akahori, H Misu, M Sakurai, Y Zen, Y Nakanuma, S Kaneko.
- Journal Title
  
  Gastroenterology 132(1)
  
  Pages: 282-293
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Comment on : Nathan DM, Buse JB, Davidson MB et al. (2006) Management of hyperglycaemia in type 2 diabetes : a consensus algorithm for the initiation and adjustment of therapy. A consensus statement from the American Diabetes Association and the European Association for the Study of Diabetes2007
- Author(s)
  Takamura T, et al.
- Journal Title
  
  Diabetologia 49
  
  Pages: 229-230
- NAID
  120000809528
- Data Source
  KAKENHI-PROJECT-17590920
[Journal Article] Regulation of adiponectin receptor expression in human liver and a hepatocyte cell line.2007
- Author(s)
  A Shimizu, T Takamura, N Matsuzawa, S Nakamura, S Nabemoto, Y Takeshita, H Misu, S Kurita, M Sakurai, M Yokoyama, Y Zen, M Sasaki, Y Nakanuma, S Kaneko.
- Journal Title
  
  Metabolism 56(11)
  
  Pages: 1478-1485
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Factors associated with improvement of fasting plasma glucose level by mealtime dosing of a rapid-acting insulin analog in type 2 diabetes2007
- Author(s)
  Takamura T, Sakurai M, Nakamura M, Shimizu A, Ota T, Misu H, Takeshita Y, Tsuchiyama N, Kurita S, Ando H, Kaneko S
- Journal Title
  
  Diabetes Res Clin Pract 75
  
  Pages: 278-284
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590920
[Journal Article] Selective estrogen receptor modulator raloxifene-associated aggravation of nonalcoholic steatohepatitis2007
- Author(s)
  Takamura T et al.
- Journal Title
  
  Intern Med 46
  
  Pages: 579-581
- NAID
  130000078717
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590920
[Journal Article] Comment on : Nathan DM, Buse JB, Davidson MB et al. (2006) Management of hyperglycaemia in type 2 diabetes : a consensus algorithm for the initiation and adjustment of therapy. A consensus statement from the American Diabetes Association and the European As sociation for the Study of Diabetes2007
- Author(s)
  Takamura T et al.
- Journal Title
  
  Diabetologia 49
  
  Pages: 229-230
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590920
[Journal Article] Insulin resistance accelerates a dietary rat model of nonalcoholic steatohepatitis2007
- Author(s)
  Ota T, Takamura T, Kurita S, Matsuzawa N, Kita Y, Uno M, Akahori H, Misu H, Sakurai M, Zen Y, Nakanuma Y, Kaneko S
- Journal Title
  
  Gastroenterology 132
  
  Pages: 282-293
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590920
[Journal Article] Selective estrogen receptor modulator raloxifene-associated aggravation of nonalcoholic steatohepatitis2007
- Author(s)
  Takamura T, Shimizu A, Komura T, Ando H, Zen Y, Minato H, Matsushita E, Kaneko S
- Journal Title
  
  Intern Med 46
  
  Pages: 579-581
- NAID
  130000078717
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590920
[Journal Article] Liver steatosis, but not fibrosis, is associated with insulin resistance in nonalcoholic fatty liver disease.2007
- Author(s)
  M Sakurai, T Takamura, T Ota, H Ando, H Akahori, K Kaji, M Sasaki, Y Nakanuma, K Miura, S Kaneko.
- Journal Title
  
  J Gastroenterol 42(4)
  
  Pages: 312-317
- NAID
  10019483538
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Lipid-induced oxidative stress causes steatohepatitis in mice fed an atherogenic diet.2007
- Author(s)
  N Matsuzawa, T Takamura, S Kurita, H Misu, T Ota, H Ando, M Yokoyama, M Honda, Y Zen, Y Nakanuma, K Miyamoto, S Kaneko.
- Journal Title
  
  Hepatology 46(5)
  
  Pages: 1392-1403
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Induction of reactive oxygen species from isolated rat glomeruli by protein kinase C activation and TNF-α stimulation, and effects of a phosphodiesterase inhibitor.2007
- Author(s)
  N Koike, T Takamura, S Kaneko.
- Journal Title
  
  Life Sci 80(18)
  
  Pages: 1721-1278
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Pioglitazone in nonalcoholic steatohepatitis2007
- Author(s)
  Ota T, Takamura T, Kaneko S
- Journal Title
  
  N Engl J Med 356:1068
- NAID
  120000806619
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590920
[Journal Article] Possible role of alpha-cell insulin resistance in exaggerated glucagon responses to arginine in type 2 diabetes.2007
- Author(s)
  N Tsuchiyama, T Takamura, H Ando, M Sakurai, A Shimizu, K Kato, S Kurita, S Kaneko.
- Journal Title
  
  Diabetes Care 30(10)
  
  Pages: 2583-2587
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Genes involved in oxidative phosphorylation are coordinately upregulated with fasting hyperglycaemia in livers of patients with type 2 diabetes.2007
- Author(s)
  H Misu, T Takamura, N Matsuzawa, A Shimizu, T Ota, M Sakurai, H Ando, K Arai, T Yamashita, M Honda, T Yamashita, S Kaneko.
- Journal Title
  
  Diabetologia 50(2)
  
  Pages: 268-277
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Management of hyperglycaemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy. A consensus statement from the American Diabetes Association and the European Association for the Study of Diabetes2007
- Author(s)
  T Takamura
- Journal Title
  
  Diabetologia 50
  
  Pages: 229-330
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Selective estrogen receptor modulator raloxifene-associated aggravation of nonalcoholic steatohepatitis.2007
- Author(s)
  T Takamura, A Shimizu, H Ando, S Kaneko.
- Journal Title
  
  Intern Med 46(9)
  
  Pages: 579-581
- NAID
  130000078717
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Factors associated with improvement of fasting plas ma glucose level by mealtime dosing of a rapid-acting insulin analog in type 2 diabetes2007
- Author(s)
  Takamura T et al.
- Journal Title
  
  Diabetes Res Clin Pract 75
  
  Pages: 278-284
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590920
[Journal Article] Genes involved in oxidative phosphorylation are coordinately upregulated with fasting hyperglycaemia in livers of patients with type 2 diabetes2007
- Author(s)
  Misu H, Takamura T, Matsuzawa N, Shimizu A, Ota T, Sakurai M, Ando H, Arai K, Yamashita T, Honda M, Yamashita T. Kaneko S
- Journal Title
  
  Diabetologia 50
  
  Pages: 268-277
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590920
[Journal Article] Genes involved in oxidative phosphorylation are coordinately upregulated with fasting hyperglycaemia in livers of patients with type 2 diabetes2007
- Author(s)
  H Misu, T Takamura, N Matsuzawa, A Shimizu, T Ota, M Sakurai, H Ando, K Arai, T Yamashita, M Honda, T Yamashita and S Kaneko.
- Journal Title
  
  Diabetologia 50(2)
  
  Pages: 268-277
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Lipid-induced oxidative stress causes steatohepatitis in mice fed an atherogenic diet2007
- Author(s)
  N Matsuzawa, T Takamura, S Kurita, H Misu, T Ota, H Ando, M Yokoyama, M Honda, Y Zen, Y Nakanuma, K Miyamoto and S Kaneko
- Journal Title
  
  Hepatology 46(5)
  
  Pages: 1392-1403
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Association of the C825T polymorphism of the G-protein beta3 subunit gene with hypertension, obesity, hyperlipidemia, insulin resistance, diabetes, diabetic complications, and diabetic therapies among Japanese2007
- Author(s)
  Havakawa T.Takamura T.Abe T.Kaneko S
- Journal Title
  
  Metabolism 56
  
  Pages: 44-48
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590920
[Journal Article] Insulin resistance accelerates a dietary rat model of nonalcoholic steatohepatitis2007
- Author(s)
  T Ota, T Takamura, S Kurita, N Matsuzawa, Y Kita, M Uno, H Akahori, H Misu, M Sakurai, Y Zen, Y Nakanuma and S Kaneko
- Journal Title
  
  Gastroenterology 132(1)
  
  Pages: 282-293
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Gene expression profiles in peripheral blood mononuclear cells reflect the pathophysiology of type 2 diabetes2007
- Author(s)
  T Takamura
- Journal Title
  
  Biochem Biophys Res Commun 361
  
  Pages: 379-384
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Gene expression profiles in peripheral blood mononuclear cells reflect the pathophysiology of type 2 diabetes.2007
- Author(s)
  T Takamura, M Honda, Y Sakai, H Ando, A Shimizu, T Ota, M Sakurai, H Misu, S Kurita, N Matsuzawa-Nagata, M Uchikata, S Nakamura, R Matoba, M Tanino, K Matsubara, S Kaneko.
- Journal Title
  
  Biochem Biophys Res Commun 361(2)
  
  Pages: 379-384
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Factors associated with improvement of fasting plasma glucose level by mealtime dosing of a rapid-acting insulin analog in type 2 diabetes2007
- Author(s)
  Takamura T, et al.
- Journal Title
  
  Diabetes Res Clin Pract 75
  
  Pages: 278-284
- Data Source
  KAKENHI-PROJECT-17590920
[Journal Article] Pioglitazone in nonalcoholic steatohepatitis.2007
- Author(s)
  T Ota, T Takamura, S Kaneko.
- Journal Title
  
  N Engl J Med 356(10)
  
  Pages: 1068-1068
- NAID
  120000806619
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Factors associated with improvement of fasting plasma glucose level by mealtime dosing of a rapid-acting insulin analog in type 2 diabetes.2007
- Author(s)
  T Takamura, M Sakurai, M Nakamura, A Shimizu, T Ota, H Misu, Y Takeshita, N Tsuchiyama, S Kurita, H Ando, S Kaneko.
- Journal Title
  
  Diabetes Res Clin Pract 75(3)
  
  Pages: 278-284
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Comment on : Nathan DM, Buse JB, Davidson MB et al. (2006) Management of hyperglycaemia in type 2 diabetes : a consensus algorithm for the initiation and adjustment of therapy. A consensus statement from the American Diabetes Association and the European Association for the Study of Diabetes.2007
- Author(s)
  Takamura, A Shimizu, H Ando, S Kaneko.
- Journal Title
  
  Diabetologia 50(1)
  
  Pages: 229-330
- NAID
  120000809528
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Tumor necrosis factor-alpha-induced production of plasminogen activator inhibitor 1 and its regulation by pioglitazone and cerivastatin in a nonmalignant human hepatocyte cell line.2006
- Author(s)
  Y Takeshita, T Takamura, E Hamaguchi, A Shimizu, T Ota, M Sakurai, S Kaneko.
- Journal Title
  
  Metabolism 55(11)
  
  Pages: 1464-1472
- NAID
  120000809721
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Profile of rhythmic gene expression in the livers of obese diabetic KK-A(y) mice2006
- Author(s)
  Ando H, Oshima Y, Yanagihara H, Hayashi Y, Takamura T, Kaneko S, Fuiimura A
- Journal Title
  
  Biochem Biophys Res Commun 346
  
  Pages: 1297-1302
- NAID
  120000809723
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590920
[Journal Article] Pancreatic exocrine and endocrine events occur concomitantly but independently during the course of fulminant type 1 diabetes2006
- Author(s)
  Kahara T, Takamura T, Sakurai M, Misu H, Usuda R, Hayakawa T, Nishimura Y, Bando Y, Nagaoka T, Nagai Y, Kaneko S
- Journal Title
  
  Diabetes Res Clin Pract 71
  
  Pages: 241-246
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590920
[Journal Article] Gender differences in the association between anthropometric indices of obesity and blood pressure in Japanese2006
- Author(s)
  Sakurai M, Miura K, Takamura T, Ota T, Ishizaki M, Morikawa Y Kirin T Naruse Y, Nakagawa H
- Journal Title
  
  Hypertens Res 29
  
  Pages: 75-80
- NAID
  10019254351
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590920
[Journal Article] Tumor necrosis factor-alpha-induced production of plasminogen activator inhibitor 1 and its regulation by pioglitazone and cerivastatin in a nonmalignant human hepatocyte cell line2006
- Author(s)
  Takeshita Y, Takamura T, Hamaguchi E, Shimizu A, Ota T, Sakurai M-Kaneko S
- Journal Title
  
  Metabolism 55
  
  Pages: 1464-1472
- NAID
  120000809721
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590920
[Journal Article] Erythrocyte sorbitol level as a predictor of the efficacy of epalrestat treatment for diabetic peripheral polyneuropathy.2006
- Author(s)
  H Ando, T Takamura, Y Nagai, S Kaneko.
- Journal Title
  
  J Diabetes Complications 20(6)
  
  Pages: 367-370
- NAID
  120000809564
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Pancreatic exocrine and endocrine events occur concomitantly but independently during the course of fulminant type 1 diabetes.2006
- Author(s)
  T Kahara, T Takamura, M Sakurai, H Misu, R Usuda, T Hayakawa, Y Nishimura, Y Bando, T Nagaoka, Y Nagai, S Kaneko.
- Journal Title
  
  Diabetes Res Clin Pract 71(3)
  
  Pages: 241-246
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18109008
[Journal Article] Erythrocyte sorbitol level as a predictor of the efficacy of epalrestat treatment for diabetic peripheral polyneuropathy2006
- Author(s)
  Ando H, Takamura T, Nagai Y, Kaneko S
- Journal Title
  
  J Diabetes Complications 20
  
  Pages: 367-370
- NAID
  120000809564
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590920
[Journal Article] Effects of grapefruit juice on the pharmacokinetics of pitavastatin and atorvastatin2005
- Author(s)
  Ando H, Tsuruoka S, Yanagihara H, Sugimoto K, Miyata M, Yamazoe Y, Takamura T, Kaneko S, Fujimura A
- Journal Title
  
  Br J Clin Pharmacol 60
  
  Pages: 494-497
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590920
[Journal Article] Daily rhythms of P-glycoprotein expression in mice2005
- Author(s)
  Ando H, Yanagihara H, Sugimoto K, Hayashi Y, Tsuruoka S, Takamura T, Kaneko S, Fujimura A
- Journal Title
  
  Chronobiol Int 26
  
  Pages: 655-665
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590920
[Journal Article] Regulation of cholesterol 7alpha-hydroxylase mRNA expression in C57BL/6 mice fed an atherogenic diet2005
- Author(s)
  Ando H, Tsuruoka S, Yamamoto H, Takamura T, Kaneko S, Fujimura A
- Journal Title
  
  Atherosclerosis 178
  
  Pages: 265-269
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590920
[Journal Article] 肝細胞の脂肪化が形成する代謝症候群の病態と分子病理2005
- Author(s)
  篁俊成ら
- Journal Title
  
  内分泌・糖尿病科 21・2
  
  Pages: 155-160
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590920
[Journal Article] Measurement of thyroid blood flow area is useful for diagnosing the cause of thyrotoxicosis2005
- Author(s)
  Kurita S, Sakurai M, Kita Y, Ota T, Ando H, Kaneko S, Takamura T
- Journal Title
  
  Thyroid 15
  
  Pages: 1249-1252
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590920
[Journal Article] Relationship between plasma hANP level and pretibial edema by pioglitazone treatment2005
- Author(s)
  Kahara T, Takamura T, Misaki T, Sakurai M, Takeshita Y, Shimizu A, Kaneko S
- Journal Title
  
  Endocr J 52
  
  Pages: 373-376
- NAID
  10016565919
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590920
[Journal Article] Cut-off point of body mass index to detect metabolic abnormality in Japanese2005
- Author(s)
  Ota T, Yamagami T, Sakurai M, Takamura T
- Journal Title
  
  J Japan Society for the Study of Obesity 11
  
  Pages: 317-322
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590920
[Journal Article] Significance of IA-2 antibody in Japanese type 1 diabetes : its association with GAD antibody2005
- Author(s)
  Ota T, Takamura T, Nagai Y, Bando Y, Usuda R
- Journal Title
  
  Diabetes Res Clin Pract 67
  
  Pages: 63-69
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590920
[Journal Article] Adiponectin receptor II in non-alcoholic fatty liver disease2005
- Author(s)
  Takamura T, Shimizu A, Matsuzawa N, Honda M, Kaneko S
- Journal Title
  
  Gut (eLetters online) 16 March
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590920
[Journal Article] Subacute thyroiditis developed in identical twins two years apart2005
- Author(s)
  Hamaguchi E, Nishimura Y. Kaneko S, Takamura T
- Journal Title
  
  Endocr J 52
  
  Pages: 559-562
- NAID
  10016782208
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590920
[Journal Article] Adiponectin receptor II in non-alcoholic fatty liver disease2005
- Author(s)
  Takamura T et al.
- Journal Title
  
  Gut (eLetters online) 16 March
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590920
[Journal Article] cDNA microarray analysis of autoimmune hepatitis, primary biliary cirrhosis and consecutive disease manifestation2005
- Author(s)
  Honda M, Kawai H, Shirota Y, Yamashita T, Takamura T, Kaneko, S
- Journal Title
  
  J Autoimmun 25
  
  Pages: 133-140
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590920
[Journal Article] Rhythmic messenger ribonucleic acid expression of clock genes and adipocytokines in mouse visceral adipose tissue2005
- Author(s)
  Ando H, Yanagihara H, Hayashi Y, Obi Y, Tsuruoka S, Takamura T, Kaneko S, Fujimura A
- Journal Title
  
  Endocrinology 146
  
  Pages: 5631-5636
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590920
[Journal Article] Tranilast prevents the progression of experimental diabetic nephropathy through suppression of enhanced extracellular matrix gene expression2005
- Author(s)
  Akahori H, Ota T, Torita M, Ando H, Kaneko S, Takamura T
- Journal Title
  
  J Pharmacol Exp Ther 314
  
  Pages: 514-521
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590920
[Journal Article] Selenoprotein P as a diabetes-associated hepatokine that impairs angiogenesis by inducing VEGF resistance in vascular endothelial cells
- Author(s)
  Ishikura K, Misu H, Kumazaki M, Takayama H,Matsuzawa-Nagata N, Tajima N, Chikamoto K, Lan F, Ando H, Ota T, Sakurai M, Takeshita Y, Kato K, Fujimura A, Miyamoto K, Saito Y, Kameo S, Okamoto Y, Takuwa Y, Takahashi K, Kidoya H, Takakura N, Kaneko S, Takamura T
- Journal Title
  
  Diabetologia
  
  Volume: (in press) (2014予定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591301
[Patent] ２型糖尿病患者の治療薬選択の補助方法，治療薬の効果予測方法及び検査方法2015
- Inventor(s)
  御簾博文、竹下有美枝、篁　俊成、金子周一
- Industrial Property Rights Holder
  金沢大学
- Industrial Property Rights Type
  特許
- Filing Date
  2015-09-10
- Overseas
- Data Source
  KAKENHI-PROJECT-26253046
[Patent] ２型糖尿病患者の治療薬選択の補助方法，治療薬の効果予測方法及び検査方法2014
- Inventor(s)
  御簾　博文、竹下　有美枝、篁　俊成、金子　周一
- Industrial Property Rights Holder
  金沢大学
- Industrial Property Rights Type
  特許
- Filing Date
  2014-09-10
- Data Source
  KAKENHI-PROJECT-26253046
[Patent] 糖尿病関連肝臓由来分泌タンパク質の2型糖尿病または血管障害の診断または治療への利用2008
- Inventor(s)
  篁俊成、金子周一、御簾博文、高倉伸幸
- Industrial Property Rights Holder
  国立大学法人金沢大学
- Filing Date
  2008-12-15
- Data Source
  KAKENHI-PROJECT-20591054
[Patent] 生理的状態分析方法、生理的状態分析システム、及びコンピュータシステムに生理的状態を分析するための処理を実行させるコンピュータープログラム2008
- Inventor(s)
  松原謙一, 下田正文, 的場亮, 谷野元彦, 中村誠二, 岡山利次, 田村卓郎, 金子周一, 篁俊成, 河合昴三
- Industrial Property Rights Holder
  (株)DNAチップ研究所, ビッツ(株)
- Filing Date
  2008-12-05
- Data Source
  KAKENHI-PROJECT-18109008
[Patent] 生理的状態分析方法、生理的状態分析システム、及びコンピュータシステムに生理的状態を分析するための処理を実行させるコンピュータープログラム2008
- Inventor(s)
  松原謙一、下田正文、的場亮、谷野元彦、中村誠二、岡山利次、田村卓郎、金子周一、篁俊成、河合昴三
- Industrial Property Rights Holder
  (株) DNAチップ研究所、ビッツ(株)
- Industrial Property Number
  2008-311346
- Filing Date
  2008-12-05
- Data Source
  KAKENHI-PROJECT-18109008
[Patent] 新規な肝疾患の予防または治療ならびにインスリン抵抗性改善剤2008
- Inventor(s)
  篁俊成, 金子周一, 安藤仁, 太田嗣人, 御簾博文, 栗田征一郎, 宇野将文金
- Industrial Property Rights Holder
  金沢大学
- Industrial Property Number
  2008-274758
- Filing Date
  2008-10-24
- Data Source
  KAKENHI-PROJECT-20591054
[Patent] 新規な肝疾患の予防または治療ならびにインスリン抵抗性改善剤2008
- Inventor(s)
  篁俊成、金子周一、安藤仁、太田嗣人、御簾博文、栗田征一郎, 宇野将文
- Industrial Property Rights Holder
  国立大学法人金沢大学
- Filing Date
  2008-10-24
- Data Source
  KAKENHI-PROJECT-20591054
[Patent] 糖尿病の有無等を判定する方法2006
- Inventor(s)
  篁, 金子ら
- Industrial Property Rights Holder
  篁, 金子ら
- Industrial Property Number
  2006-284625
- Filing Date
  2006-10-19
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590920
[Patent] インスリン抵抗性誘導・血管新生抑制作用を有する糖尿病関連肝臓由来分泌淡白2006
- Inventor(s)
  篁, 金子ら
- Industrial Property Rights Holder
  篁, 金子ら
- Industrial Property Number
  2006-206747
- Filing Date
  2006-07-28
- Data Source
  KAKENHI-PROJECT-17590920
[Patent] インスリン抵抗性誘導・血管新生抑制作用を有する糖尿病関連肝臓由来分泌蛋白2006
- Inventor(s)
  篁, 金子ら
- Industrial Property Rights Holder
  篁, 金子ら
- Industrial Property Number
  2006-206747
- Filing Date
  2006-07-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590920
[Patent] 糖尿病の病態と関連して発現変動する遺伝子群2005
- Inventor(s)
  篁, 金子ら
- Industrial Property Rights Holder
  篁, 金子ら
- Filing Date
  2005-04-22
- Data Source
  KAKENHI-PROJECT-17590920
[Patent] 糖尿病の病態と関連して発現変動する遺伝子群2005
- Inventor(s)
  篁, 金子ら
- Industrial Property Rights Holder
  篁, 金子ら
- Filing Date
  2005-04-22
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590920
[Presentation] 連続肝生検研究からみたNAFLD病理進展におよぼす糖尿病の意義2021
- Author(s)
  迫佐央理, 竹下有美枝, 安藤仁, 金子周一, 篁俊成
- Organizer
  第64回　日本糖尿病学会年次学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19503
[Presentation] セレノタンパク質Pを介した還元ストレスは褐色脂肪における寒冷誘発性のUCP1活性化と熱産生を障害する2021
- Author(s)
  Oo Hein Ko, 高山浩昭, Oo Swe Mar, 石井清朗, 篁俊成
- Organizer
  第64回　日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17H04199
[Presentation] 連続肝生検研究からみたNAFLD病理進展におよぼす糖尿病の意義2021
- Author(s)
  迫佐央理, 竹下有美枝, 安藤仁, 金子周一, 篁俊成
- Organizer
  第64回　日本糖尿病学会年次学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04199
[Presentation] NAFLD/NASH研究の最前線～連続肝生検から見えてきたdiabetic steatohepatitis～2020
- Author(s)
  篁俊成
- Organizer
  第63回日本糖尿病学会年次学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K19560
[Presentation] NAFLD/NASH研究の最前線～連続肝生検から見えてきたdiabetic steatohepatitis～2020
- Author(s)
  篁俊成
- Organizer
  第63回日本糖尿病学会年次学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04199
[Presentation] Novel role of selenoprotein P in immunity2020
- Author(s)
  篁俊成
- Organizer
  第63回日本糖尿病学会年次学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04199
[Presentation] Novel role of selenoprotein P in immunity2020
- Author(s)
  篁俊成
- Organizer
  第63回日本糖尿病学会年次学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K19560
[Presentation] Locally-circulating selenoprotein P regulates ROS-mediated thermogenesis in brown fat2019
- Author(s)
  Hein Ko Oo、高山浩昭、Swe Mar Oo、石井清朗、篁俊成
- Organizer
  第31回分子糖尿病学シンポジウム
- Data Source
  KAKENHI-PROJECT-18K19560
[Presentation] EPA製剤が2型糖尿病患者の血中セレノプロテインP濃度と臓器特異的インスリン感受性に及ぼす効果2019
- Author(s)
  寺村千里，竹下有美枝，高山浩昭，海古井由佳，田中健雄，金森岳広，篁俊成
- Organizer
  第34回日本糖尿病合併症学会
- Data Source
  KAKENHI-PROJECT-18K19560
[Presentation] Diabetes-associated systemic pathology induced by hepatokines2019
- Author(s)
  御簾博文，篁俊成
- Organizer
  第63回日本糖尿病学会年次学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K19560
[Presentation] EPA製剤が2型糖尿病患者の血中セレノプロテインP濃度と臓器特異的インスリン感受性に及ぼす効果2019
- Author(s)
  寺村千里，竹下有美枝，高山浩昭，海古井由佳，田中健雄，金森岳広，篁俊成
- Organizer
  第34回日本糖尿病合併症学会
- Data Source
  KAKENHI-PROJECT-17H04199
[Presentation] Anti-oxidative hepatokine selenoprotein P impairs brown fat thermogenesis by suppressing mitochondrial ROS2019
- Author(s)
  Hiroaki Takayama, Swe Mar Oo, Hirofumi Misu, Kiyo-aki Ishii, Toshinari Takamura
- Organizer
  Keystone Symposia Obesity and Adipose Tissue Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19560
[Presentation] 抗酸化ヘパトカイン”セレノプロテインP”が惹起する全身の糖尿病関連病態2019
- Author(s)
  高山浩昭、御簾博文、斎藤芳郎、篁俊成
- Organizer
  第92回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-18K19560
[Presentation] 抗酸化ヘパトカイン”セレノプロテインP”が惹起する全身の糖尿病関連病態2019
- Author(s)
  高山浩昭、御簾博文、斎藤芳郎、篁俊成
- Organizer
  第92回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04199
[Presentation] 非アルコール性脂肪性肝疾患のReal-World Date：肝病理進展に寄与する病態2019
- Author(s)
  篁俊成
- Organizer
  第53回糖尿病学の進歩
- Invited
- Data Source
  KAKENHI-PROJECT-18K19560
[Presentation] Diabetes-associated systemic pathology induced by hepatokines2019
- Author(s)
  御簾博文，篁俊成
- Organizer
  第63回日本糖尿病学会年次学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04199
[Presentation] インスリン抵抗性や運動抵抗性を惹起するセレノプロテインPに対するEPAの制御機構2019
- Author(s)
  鴨下恭子，石井清明，田島奈津美，白崎尚芳，高山浩昭，竹下有美枝，金子周一，篁俊成
- Organizer
  第34回日本糖尿病合併症学会
- Data Source
  KAKENHI-PROJECT-18K19560
[Presentation] インスリン抵抗性や運動抵抗性を惹起するセレノプロテインPに対するEPAの制御機構2019
- Author(s)
  鴨下恭子，石井清明，田島奈津美，白崎尚芳，高山浩昭，竹下有美枝，金子周一，篁俊成
- Organizer
  第34回日本糖尿病合併症学会
- Data Source
  KAKENHI-PROJECT-17H04199
[Presentation] 非アルコール性脂肪性肝疾患のReal-World Date：肝病理進展に寄与する病態2019
- Author(s)
  篁俊成
- Organizer
  第53回糖尿病学の進歩
- Invited
- Data Source
  KAKENHI-PROJECT-17H04199
[Presentation] Search for inhabitors against selenoprotein P that cause insulin resistance and excersise resistance.2019
- Author(s)
  Xingyu Yao, Hiroaki Takayama, Kiyo-aki Ishii, Toshinari Takamura
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K19560
[Presentation] 摂取カロリー設定と3大栄養素バランスに関する論考 Issues on dietary calorie and macronutrient balance2019
- Author(s)
  篁俊成
- Organizer
  第92回日本内分泌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-18K19560
[Presentation] 摂取カロリー設定と3大栄養素バランスに関する論考 Issues on dietary calorie and macronutrient balance2019
- Author(s)
  篁俊成
- Organizer
  第92回日本内分泌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04199
[Presentation] Anti-oxidative hepatokine selenoprotein P impairs brown fat thermogenesis by suppressing mitochondrial ROS2019
- Author(s)
  Hiroaki Takayama, Swe Mar Oo, Hirofumi Misu, Kiyo-aki Ishii, Toshinari Takamura
- Organizer
  Keystone Symposia Obesity and Adipose Tissue Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04199
[Presentation] 肝臓-骨格筋連関が形成する糖尿病の新病態2018
- Author(s)
  篁俊成
- Organizer
  第5回肝臓と糖尿病・代謝研究会
- Invited
- Data Source
  KAKENHI-PROJECT-18K19560
[Presentation] Gamma-glutamyltransferase levels reflect glycaemic status in type 2 diabetic people treated with an SGLT2 inhibitor2018
- Author(s)
  T. Takamura, K. Kaku, A. Yoshida, H. Kusakabe, H. Suganami
- Organizer
  the 54th EASD Annual Meeting 2018 in Berlin, Germany
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04199
[Presentation] Gamma-glutamyltransferase levels reflect glycaemic status in type 2 diabetic people treated with an SGLT2 inhibitor2018
- Author(s)
  T. Takamura, K. Kaku, A. Yoshida, H. Kusakabe, H. Suganami
- Organizer
  the 54th EASD Annual Meeting 2018 in Berlin, Germany
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19560
[Presentation] Lessons from type 2 diabetic liver2018
- Author(s)
  篁俊成
- Organizer
  第84回日本生化学会東北支部会
- Invited
- Data Source
  KAKENHI-PROJECT-18K19560
[Presentation] 肝臓-骨格筋連関が形成する糖尿病の病態2018
- Author(s)
  篁俊成
- Organizer
  日本薬学会第138年会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04199
[Presentation] Lessons from type 2 diabetic liver2018
- Author(s)
  篁俊成
- Organizer
  第84回日本生化学会東北支部会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04199
[Presentation] 脂肪肝とインスリン抵抗性2018
- Author(s)
  篁俊成
- Organizer
  第52回糖尿病学の進歩
- Invited
- Data Source
  KAKENHI-PROJECT-17H04199
[Presentation] 肝臓-骨格筋連関が形成する糖尿病の新病態2018
- Author(s)
  篁俊成
- Organizer
  第5回肝臓と糖尿病・代謝研究会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04199
[Presentation] 肥満症治療におけるヘパトカインの意義2017
- Author(s)
  篁俊成
- Organizer
  第35回日本肥満症治療学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04199
[Presentation] Insulin receptor substrate 1 is selectively degraded by starvation-induced autophagy2017
- Author(s)
  Hirobumi Igawa, Akihiro Kikuchi, Yumiko Tahira, Toshinari Takamura
- Organizer
  Keystone Symposia 2017 Conference (J4: Obesity and adipose tissue biology)
- Place of Presentation
  Keystone, Colorado, USA
- Year and Date
  2017-01-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461329
[Presentation] Effect of ursodeoxycholic acid added to dipeptidyl peptidase-4 inhibitor on GLP-1 secretion and glucose tolerance in subjects with type 2 diabetes2017
- Author(s)
  Kosuke Shima, Yumie Takeshita, Hirofumi Misu, Tsuguhito Ota, Toshinari Takamura
- Organizer
  The Keystone Symposia Conference C1: Bile Acid Receptors as Signal Integrators in Liver and Metabolism,
- Place of Presentation
  モントレー（カリフォルニア、米国）
- Year and Date
  2017-03-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461329
[Presentation] 肝臓から考える肥満2型糖尿病治療2017
- Author(s)
  篁俊成
- Organizer
  第38回日本肥満学会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04199
[Presentation] Regulation of Insulin Signaling Molecules by Selective Autophagy in Mice with Proteasome Dysfunction and Starvation2017
- Author(s)
  Akihiro Kikuchi, Hirobumi Igawa, Yumiko Tahira, Toshinari Takamura
- Organizer
  Keystone Symposia 2017 Conference (J3: Diabetes)
- Place of Presentation
  Keystone, Colorado, USA
- Year and Date
  2017-01-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461329
[Presentation] 日本人NAFLDの病理におよぼす高血糖の重要性（ランチョンセミナー）2016
- Author(s)
  篁俊成
- Organizer
  第31回日本糖尿病合併症学会
- Place of Presentation
  仙台
- Year and Date
  2016-10-08
- Invited
- Data Source
  KAKENHI-PROJECT-26461329
[Presentation] 【新時代の慢性肝疾患研究】肝臓代謝リモデリングによる栄養恒常性の維持と破綻（ワークショップ）2016
- Author(s)
  篁俊成
- Organizer
  第48回日本臨床分子形態学会学術集会
- Place of Presentation
  熊本
- Year and Date
  2016-09-23
- Invited
- Data Source
  KAKENHI-PROJECT-26461329
[Presentation] 肝と代謝制御セレノプロテインPの運動抵抗性における意義と骨格筋型受容体の同定（シンポジウム）2016
- Author(s)
  篁俊成、御簾博文
- Organizer
  第59回日本糖尿病学会年次学術集会
- Place of Presentation
  京都
- Year and Date
  2016-05-21
- Invited
- Data Source
  KAKENHI-PROJECT-26461329
[Presentation] 肝臓のエネルギー代謝調節におけるタンパク質分解系の意義（ワークショップ）2016
- Author(s)
  篁俊成
- Organizer
  第3回肝臓と糖尿病・代謝研究会
- Place of Presentation
  金沢
- Year and Date
  2016-07-16
- Invited
- Data Source
  KAKENHI-PROJECT-26461329
[Presentation] 栄養代謝経路間クロストークを介した肝臓代謝リモデリング2015
- Author(s)
  篁俊成
- Organizer
  第2回肝臓と糖尿病・代謝研究会
- Place of Presentation
  山口県国際総合センター（山口県、下関市）
- Year and Date
  2015-05-23
- Invited
- Data Source
  KAKENHI-PROJECT-26461329
[Presentation] ヘパトカイン解析から見えてきた糖尿病の新病態2015
- Author(s)
  篁　俊成
- Organizer
  第49回糖尿病学の進歩
- Place of Presentation
  ホテルグランヴィア岡山（岡山県、岡山市）
- Year and Date
  2015-02-21
- Invited
- Data Source
  KAKENHI-PROJECT-26461329
[Presentation] 新たな糖尿病合併症に迫る「Diabetic Cirrhosis Revisited」2015
- Author(s)
  篁俊成
- Organizer
  第30回日本糖尿病合併症学会
- Place of Presentation
  名古屋国際会議場（愛知県、名古屋市）
- Year and Date
  2015-11-27
- Invited
- Data Source
  KAKENHI-PROJECT-26461329
[Presentation] Palmitate and eicosapentaenoic acid oppositely regulate selenoprotein P gene expression in H4IIEC hepatocytes2015
- Author(s)
  Takamura T, Natsumi N, Takayama H, Misu H, Kaneko S
- Organizer
  Keystone Symposia, Liver Metabolism and Nonalcoholic Fatty Liver Disease (NAFLD) (X8)
- Place of Presentation
  Fairmont Chateau Whistler (Whistler, British Columbia, Canada)
- Year and Date
  2015-03-25
- Data Source
  KAKENHI-PROJECT-26461329
[Presentation] Efficacy and Safety of Once-weekly Dulaglutide versus Once-daily Liraglutide in Japanese patients with Type 2 Diabetes2015
- Author(s)
  Toshinari Takamura, Jun-ichiro Miyagawa, Masato Odawara, Yasushi Takita, Noriyuki Iwamoto, Takeshi Imaoka
- Organizer
  The 75th Scientific Sessions American Diabetes Association (ADA)
- Place of Presentation
  Boston Convention & Exhibition Center（ボストン、米国）
- Year and Date
  2015-06-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461329
[Presentation] 栄養バランスから再考する2型糖尿病の病態と治療2015
- Author(s)
  篁俊成
- Organizer
  第89回日本糖尿病学会中部地方会
- Place of Presentation
  静岡県コンベンションアーツセンター（グランシップ）（静岡県、静岡市）
- Year and Date
  2015-10-04
- Invited
- Data Source
  KAKENHI-PROJECT-26461329
[Presentation] 肥満に伴う肝障害の基礎と臨床2015
- Author(s)
  篁俊成
- Organizer
  第36回日本肥満学会
- Place of Presentation
  名古屋国際会議場（愛知県、名古屋市）
- Year and Date
  2015-10-02
- Invited
- Data Source
  KAKENHI-PROJECT-26461329
[Presentation] インクレチン療法―現状と未来への可能性「インクレチンの多面的作用　NASH・NAFLDを改善するか?」2015
- Author(s)
  篁俊成, 竹下有美枝
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  山口県国際総合センター（山口県、下関市）
- Year and Date
  2015-05-21
- Invited
- Data Source
  KAKENHI-PROJECT-26461329
[Presentation] 基礎・臨床研究と地域連携で挑む糖尿病医療2015
- Author(s)
  篁俊成
- Organizer
  第13回日本予防医学会学術総会
- Place of Presentation
  フレンドパーク石川（石川県勤労者福祉文化会館）（石川県、金沢市）
- Year and Date
  2015-06-20
- Invited
- Data Source
  KAKENHI-PROJECT-26461329
[Presentation] A satiety-induced hepatokine LECT2 causes skeletal muscle insulin resistance via JNK activation2014
- Author(s)
  Takamura T
- Organizer
  2014 International Conference on Diabetes and Metabolism (ICDM)
- Place of Presentation
  Kintex Ilsan (Gyeonggido, Korea)
- Year and Date
  2014-10-18
- Invited
- Data Source
  KAKENHI-PROJECT-26461329
[Presentation] ヘパトカインを介した肝臓-骨格筋連関によるエネルギー代謝調節2014
- Author(s)
  篁俊成
- Organizer
  第57回日本糖尿病学会年次学術集会、シンポジウム13「インスリン抵抗性の新展開ーアディポサイトカインから慢性炎症までー」
- Place of Presentation
  大阪
- Year and Date
  2014-05-23
- Data Source
  KAKENHI-PROJECT-23591301
[Presentation] ヘパトカインを介した肝臓-骨格筋連関によるエネルギー代謝調節2014
- Author(s)
  篁　俊成
- Organizer
  第57回日本糖尿病学会年次学術集会、シンポジウム
- Place of Presentation
  大阪国際会議場（大阪府、大阪市）
- Year and Date
  2014-05-23
- Invited
- Data Source
  KAKENHI-PROJECT-26461329
[Presentation] 肝臓代謝リモデリングによる栄養恒常性の維持と破綻2014
- Author(s)
  篁　俊成
- Organizer
  第35回日本肥満学会、ランチョンセミナー
- Place of Presentation
  フェニックスシーガイアリゾートコンベンションセンター（宮崎県、宮崎市）
- Year and Date
  2014-10-25
- Invited
- Data Source
  KAKENHI-PROJECT-26461329
[Presentation] Remodeling of nutrient homeostasis by obesity-associated proteasome dysfunction2014
- Author(s)
  Takamura T
- Organizer
  2014 International Conference on Diabetes and Metabolism (ICDM)
- Place of Presentation
  Kintex Ilsan (Gyeonggido, Korea)
- Year and Date
  2014-10-17
- Invited
- Data Source
  KAKENHI-PROJECT-26461329
[Presentation] 食と肥満による肝臓代謝リモデリング2014
- Author(s)
  篁　俊成
- Organizer
  第35回日本肥満学会、シンポジウム
- Place of Presentation
  フェニックスシーガイアリゾートコンベンションセンター（宮崎県、宮崎市）
- Year and Date
  2014-10-25
- Invited
- Data Source
  KAKENHI-PROJECT-26461329
[Presentation] 食事療法のサイエンス2014
- Author(s)
  篁俊成
- Organizer
  第48回糖尿病学の進歩、シンポジウム「食事療法と運動療法の科学的側面をさぐる」
- Place of Presentation
  札幌
- Year and Date
  2014-03-07
- Data Source
  KAKENHI-PROJECT-23591301
[Presentation] 肝臓から考える糖尿病に対する食事・運動療法2014
- Author(s)
  篁　俊成
- Organizer
  第29回日本糖尿病合併症学会、シンポジウム
- Place of Presentation
  都市センターホテル（東京都、千代田区）
- Year and Date
  2014-10-03
- Invited
- Data Source
  KAKENHI-PROJECT-26461329
[Presentation] 糖尿病医療における食事療法の課題2013
- Author(s)
  篁俊成
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  熊本(シンポジウム)
- Year and Date
  2013-05-17
- Data Source
  KAKENHI-PROJECT-23591301
[Presentation] 高血糖昏睡の治療.糖尿病学の進歩2013
- Author(s)
  篁俊成
- Place of Presentation
  四日市市(教育講演)
- Year and Date
  2013-02-15
- Data Source
  KAKENHI-PROJECT-23591301
[Presentation] 疫学・臨床・基礎研究を統合して挑む糖尿病医療2013
- Author(s)
  篁俊成
- Organizer
  第83回日本衛生学会
- Place of Presentation
  金沢(シンポジウム)
- Year and Date
  2013-03-24
- Data Source
  KAKENHI-PROJECT-23591301
[Presentation] Organ-specific fat accumulation and insulin resistance among the liver, skeletal muscle and adipose tissue in people with nonalcoholic fatty liver disease2013
- Author(s)
  Takamura T, Kato K-I, Misu H, Takeshita Y, Kaneko S
- Organizer
  49th Annual Meeting of the European Association for the Study of Diabetes (EASD)
- Place of Presentation
  Barcelona (Spain)
- Year and Date
  2013-09-26
- Data Source
  KAKENHI-PROJECT-23591301
[Presentation] スローエイジングを目指す血糖制御とその向こうにあるもの2013
- Author(s)
  篁俊成
- Organizer
  日本循環器予防学会
- Place of Presentation
  金沢(教育講演)
- Year and Date
  2013-06-15
- Data Source
  KAKENHI-PROJECT-23591301
[Presentation] NAFLD : Cause and Consequence of Diabetes2012
- Author(s)
  篁　俊成
- Organizer
  第55回日本糖尿病学会年次学術集会
- Place of Presentation
  パシフィコ横浜、横浜、神奈川
- Invited
- Data Source
  KAKENHI-PROJECT-23591301
[Presentation] NAFLD : Cause and Consequence of Diabetes2012
- Author(s)
  篁俊成
- Organizer
  第55回日本糖尿病学会年次学術集会
- Place of Presentation
  横浜(教育講演)
- Year and Date
  2012-05-18
- Data Source
  KAKENHI-PROJECT-23591301
[Presentation] 肝臓における栄養代謝:その基礎と進歩2012
- Author(s)
  篁俊成
- Organizer
  平成24年度日本肝臓学会前期教育講演会(第48回日本肝臓学会総会)
- Place of Presentation
  金沢(教育講演)
- Year and Date
  2012-06-09
- Data Source
  KAKENHI-PROJECT-23591301
[Presentation] Dual effects of ROS and possible reductive stress on insulin signal transduction in hepatocytes2012
- Author(s)
  Takamura T, Misu H, Kaneko S
- Organizer
  Keystone Symposia- Pathogenesis of Diabetes : Emerging Insights into Molecular Mechanisms
- Place of Presentation
  Santa Fe, New Mexico (USA)
- Year and Date
  2012-02-02
- Data Source
  KAKENHI-PROJECT-23591301
[Presentation] Proteasome dysfunction links obesity and endoplasmic reticulum stress leading to insulin resistance in the liver2012
- Author(s)
  Toshiki Otoda， Toshinari Takamura, Hirofumi Misu, Tsuguhito Ota, Shuichi Kaneko
- Organizer
  9th IDF-WPR Congress and 4th AASD Scientific Meeting
- Place of Presentation
  京都国際会館、Kyoto, Kyoto
- Data Source
  KAKENHI-PROJECT-23591301
[Presentation] 臓器特異的インスリン抵抗性（ＩＲ）指標の妥当性および肝病理像との関連2012
- Author(s)
  加藤健一郎，竹下有美枝，御簾博文，太田嗣人，徳山薫平，松久宗英，長坂昌一郎，金子周一，篁俊成
- Organizer
  第55回日本糖尿病学会年次学術集会
- Place of Presentation
  パシフィコ横浜、横浜、神奈川
- Data Source
  KAKENHI-PROJECT-23591301
[Presentation] Positioning of vildagliptine vs. liraglutide as a step-up from sitagliptine-based regimens in people with type 2 diabetes : ERA-DM Study Chapter 22012
- Author(s)
  Takamura T
- Organizer
  9th IDF-WPR Congress and 4th AASD Scientific Meeting(第9回国際糖尿病連合西太平洋地区会議/第4回アジア糖尿病学会学術集会)
- Place of Presentation
  Kyoto (Japan)
- Year and Date
  2012-11-26
- Data Source
  KAKENHI-PROJECT-23591301
[Presentation] 糖質制限食療法をアートではなくサイエンスとして確立するための課題とロードマップ2012
- Author(s)
  篁俊成
- Organizer
  第55回日本糖尿病学会年次学術集会
- Place of Presentation
  横浜(シンポジウム)
- Year and Date
  2012-05-18
- Data Source
  KAKENHI-PROJECT-23591301
[Presentation] ヘパトカインが形成する2型糖尿病の病態2012
- Author(s)
  篁俊成
- Organizer
  第46回糖尿病学の進歩
- Place of Presentation
  盛岡(教育講演)
- Year and Date
  2012-03-03
- Data Source
  KAKENHI-PROJECT-23591301
[Presentation] Ectopic fat accumulation and distant organ-specific insulin resistance in people with nonalcoholic fatty liver disease2012
- Author(s)
  Ken-ichiro Kato， Yumie Takeshita, Hirofumi Misu, Tsuguhito Ota, Kumpei Tokuyama, Soichiro Nagasaka, Munehisa Matsuhisa, Shuichi Kaneko, Toshinari Takamura
- Organizer
  9th IDF-WPR Congress and 4th AASD Scientific Meeting
- Place of Presentation
  京都国際会館、Kyoto, Kyoto
- Data Source
  KAKENHI-PROJECT-23591301
[Presentation] ヘパトカインが形成する2型糖尿病の病態2012
- Author(s)
  篁　俊成
- Organizer
  第46回糖尿病学の進歩(招待講演)
- Place of Presentation
  盛岡、盛岡グランドホテル
- Data Source
  KAKENHI-PROJECT-23591301
[Presentation] 肥満は肝プロテアソーム機能障害を介して小胞体ストレスとインスリン抵抗性を誘導する2012
- Author(s)
  乙田敏城，篁俊成，御簾博文，太田嗣人，金子周一
- Organizer
  第62回日本体質医学会総会
- Place of Presentation
  大阪国際会議場、大阪、大阪
- Data Source
  KAKENHI-PROJECT-23591301
[Presentation] Proteasome dysfunction in obesity contributes to ER stress, enhanced autophagy and insulin resistance in type 2 diabetic liver.2011
- Author(s)
  篁俊成, et al.
- Organizer
  Keystone Symposia - Type 2 Diabetes, Insulin Resistance and Metabolic Dysfunction
- Place of Presentation
  Keystone Resort, Keystone, Colorado, USA
- Year and Date
  2011-01-15
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] Anovel hepatokine selenoprotein P causes insulin resistance by suppressing AMPK2011
- Author(s)
  Hirofumi Misu, Kazuhide Ishikura, Hiroaki Takayama, Hiroto Hayashi, Tsuguhito Ota, Shuichi Kaneko, Toshinari Takamura
- Organizer
  Keystone Symposia-Obesity
- Place of Presentation
  Keystone Resort, Keystone, Colorado, USA
- Year and Date
  2011-01-16
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] セレノプロテインPによるVEGF抵抗性とメトホルミンによる制御の可能性2011
- Author(s)
  篁俊成
- Organizer
  第16回アディポサイエンス研究会
- Place of Presentation
  大阪(講演)
- Year and Date
  2011-08-20
- Data Source
  KAKENHI-PROJECT-23591301
[Presentation] 過栄養状態の肝臓が形成する2型糖尿病の病態2011
- Author(s)
  篁俊成
- Organizer
  第45回糖尿病学の進歩
- Place of Presentation
  福岡
- Year and Date
  2011-02-18
- Data Source
  KAKENHI-PROJECT-23591301
[Presentation] 肥満による肝インスリン抵抗性形成におけるプロテアソーム機能異常の意義．2011
- Author(s)
  篁　俊成
- Organizer
  第5回Diabetes Leading-edge Conference(招待講演)
- Place of Presentation
  滋賀、ロイヤルオークホテル
- Data Source
  KAKENHI-PROJECT-23591301
[Presentation] スローエイジングを目指す2型糖尿病の全人的ケア2011
- Author(s)
  篁俊成
- Organizer
  第52回北陸支部生涯教育講演会
- Place of Presentation
  金沢大学十全講堂、金沢市、石川(招待講演)
- Year and Date
  2011-03-13
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] Proteasome dysfunction in obesity contributes to ER stress, enhanced autophagy and insulin resistance in type 2 diabetic liver2011
- Author(s)
  Toshinari Takamura, Toshiki Otoda, Hirofumi Misu, Tsuguhito Ota, and Shuichi Kaneko
- Organizer
  Keystone Symposia- Type 2 Diabetes, Insulin Resistance and Metabolic Dysfunction
- Place of Presentation
  Keystone, Colorado (USA)
- Year and Date
  2011-01-15
- Data Source
  KAKENHI-PROJECT-23591301
[Presentation] 過栄養状態の肝臓が形成する2型糖尿病の病態2011
- Author(s)
  篁俊成
- Organizer
  第45回糖尿病学の進歩
- Place of Presentation
  福岡国際会議場、福岡市、福岡(招待講演)
- Year and Date
  2011-02-18
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] Proteasome dysfunction in obesity contributes to ER stress, enhanced autophagy and insulin resistance in type 2 diabetic liver2011
- Author(s)
  Toshinari Takamura, Toshiki Otoda, Hirofumi Misu, Tsuguhito Ota, Shuichi Kaneko
- Organizer
  Keystone Symposia-Obesity
- Place of Presentation
  Keystone Resort, Keystone, Colorado, USA
- Year and Date
  2011-01-15
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] 肝臓と糖代謝―Lessons from Type 2 Diabetic Liver2011
- Author(s)
  篁　俊成，金子周一
- Organizer
  第47回日本肝臓学会総会(招待講演)
- Place of Presentation
  東京、ホテルグランパシフィック LE DAIBA
- Data Source
  KAKENHI-PROJECT-23591301
[Presentation] セレノプロテインPによるVEGF抵抗性とメトホルミンによる制御の可能性2011
- Author(s)
  篁　俊成，御簾博文，金子周一
- Organizer
  第16回アディポサイエンス研究会(招待講演)
- Place of Presentation
  大阪、千里阪急ホテル
- Data Source
  KAKENHI-PROJECT-23591301
[Presentation] スローエイジングを見据えた糖尿病の総合的治療戦略2011
- Author(s)
  篁俊成
- Organizer
  第50回日本臨床検査医学会東海・北陸支部総会、第322回日本臨床化学会、東海・北陸支部例会連合大会
- Place of Presentation
  金沢(シンポジウム)
- Year and Date
  2011-03-13
- Data Source
  KAKENHI-PROJECT-23591301
[Presentation]2011
- Author(s)
  Misu H, Ishikura K, Takayama H, Hayashi H, Ota T, Kaneko S, Takamura T
- Organizer
  Keystone Symposia - Obesity
- Place of Presentation
  Keystone Resort, Keystone, Colorado, USA
- Year and Date
  2011-01-16
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] Selenoprotein P as a hepatokine that causes insulin resistance2011
- Author(s)
  Takamura T
- Organizer
  The 2011 International Conference on Diabetes and Metabolism(招待講演)
- Place of Presentation
  Seoul (Korea)、Grand Hilton Seoul Hotel
- Data Source
  KAKENHI-PROJECT-23591301
[Presentation] スローエイジングを目指す2型糖尿病の全人的ケア2011
- Author(s)
  篁俊成
- Organizer
  第52回日本内科学会北陸支部
- Place of Presentation
  金沢(生涯教育講演会)
- Year and Date
  2011-03-13
- Data Source
  KAKENHI-PROJECT-23591301
[Presentation] Selenoprotein P as a hepatokine that causes insulin resistance2011
- Author(s)
  Takamura T
- Organizer
  The 2011 International Conference on Diabetes and Metabolism
- Place of Presentation
  Grand Hilton Seoul Hotel, Seoul (Korea)(Lecture)
- Year and Date
  2011-11-11
- Data Source
  KAKENHI-PROJECT-23591301
[Presentation] スローエイジングを見据えた糖尿病の総合的治療戦略2011
- Author(s)
  篁俊成
- Organizer
  第50回日本臨床検査医学会東海・北陸支部総会、第322回日本臨床化学会、東海・北陸支部例会連合大会シンポジウム
- Place of Presentation
  金沢大学附属病院宝ホール、金沢市、石川(招待講演)
- Year and Date
  2011-03-13
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] スローエイジングを目指す2型糖尿病の全人的ケア.2011
- Author(s)
  篁俊成
- Organizer
  第52回北陸支部生涯教育講演会
- Place of Presentation
  金沢大学附属病院宝ホール、金沢市、石川
- Year and Date
  2011-03-13
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] 肝臓と糖代謝—Lessons from Type 2 Diabetic Liver2011
- Author(s)
  篁俊成、御簾博文、金子周一
- Organizer
  第47回日本肝臓学会総会
- Place of Presentation
  東京(講演)
- Year and Date
  2011-06-02
- Data Source
  KAKENHI-PROJECT-23591301
[Presentation] 過栄養状態の肝臓が形成する2型糖尿病の病態.2011
- Author(s)
  篁俊成
- Organizer
  第45回糖尿病学の進歩
- Place of Presentation
  福岡
- Year and Date
  2011-02-18
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] Selenoprotein P : A liver-derived hormone regulating systemic insulin sensitivity.2010
- Author(s)
  Misu H, Takayama H, Kaneko H, Takamura T
- Organizer
  14th International Congress of Endocrinology
- Place of Presentation
  国立京都国際会館、(京都)
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] Glycemic control predicts for liver fibrosis progression in Japanese patients with NAFLD who underwent consecutive liver biopsies2010
- Author(s)
  Takeshita Y, Takamura T, Hamaguchi E, Zen Y, Misu H, Arai K, Yamashita T, Mizukoshi E, Sasaki M, Nakahama Y, Kaneko S
- Organizer
  45th Annual Meeting of the European Associationfor the Study of the Liver
- Place of Presentation
  Reed Messe Wien Exhibition & Congress Center, Austria, Vienna
- Year and Date
  2010-04-15
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] 肝脂肪化と炎症・インスリン抵抗性をつなぐ分子メカニズム-パルミチン酸処置H4IIEC肝細胞モデルを用いた検討2010
- Author(s)
  御簾博文, 篁俊威, 金子周一
- Organizer
  第96回日本消化器病学会、ワークショップ
- Place of Presentation
  新潟県民会館、新潟市、新潟
- Year and Date
  2010-04-22
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] CCR5 Promotes Adipose Tissue Inflammation and Whole-Body Insulin Resistance2010
- Author(s)
  Ota T, Kitade H, Sawamoto K, Inoue H, Takamura T, MiyamotoK, Mukaida N, Kaneko S
- Organizer
  8th International Diabetes Federation Western Pacific Region Congress
- Place of Presentation
  BEXCO, Busan, Korea(一般演題(ポスター))
- Year and Date
  2010-10-19
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] CCR5 Ablation Prevents Insulin Resistance Induced by High-Fat Feedingor Leptin Deficiency2010
- Author(s)
  Ota T, Kitade H, Sawamoto K, Inoue H, Takamura T, Miyamoto K, Mukaida N, Kaneko S
- Organizer
  American Diabetes Association 70th Scientific Sessions
- Place of Presentation
  Orange County ConventionCenter, Orlando, Florida, USA(一般演題(口演))
- Year and Date
  2010-06-30
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] Molecular pathology underlying insulin resistance in type 2 diabetic liver.2010
- Author(s)
  篁俊成, 御簾博文, 金子周一
- Organizer
  第53回日本糖尿病学会年次学術集会シンポジウム
- Place of Presentation
  ホテルグランヴィア岡山、岡山市、岡山
- Year and Date
  2010-05-29
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] Nutrition and fitness for prevention/treatment of NAFLD/NASH2010
- Author(s)
  Toshinari Takamura, Shuichi Kaneko
- Organizer
  The 9th Single Topic Conference NASH 2010
- Place of Presentation
  グランドプリンスホテル高輪、品川、東京(招待講演)
- Year and Date
  2010-11-19
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] Dose-dependent dual effects of hydrogen peroxide on insulin signal transduction in H4IIEC hepatocytes2010
- Author(s)
  Iwakami S, Misu H, Sugimori M, Matsugo S, Kaneko S, Takamura T
- Organizer
  14th International Congress of Endocrinology
- Place of Presentation
  国立京都国際会館、(京都)
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] アンチエイジングを見据えた2型糖尿病の総合的治療戦略.2010
- Author(s)
  篁俊成
- Organizer
  BioJapan 2010講演
- Place of Presentation
  パシフィコ横浜、横浜市、神奈川
- Year and Date
  2010-09-30
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] 糖尿病臨床医として脂肪肝をどう捉えるか2010
- Author(s)
  篁俊成
- Organizer
  第44回糖尿病学の進歩教育講演
- Place of Presentation
  大阪国際会議場、大阪市、大阪
- Year and Date
  2010-03-06
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] スローエイジング糖尿病ケアにおけるインスリン療法のあり方2010
- Author(s)
  篁俊成
- Organizer
  第25回日本糖尿病合併症学会総会ランチョンセミナー
- Place of Presentation
  びわ湖ホール、大津市、滋賀(招待講演)
- Year and Date
  2010-10-23
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] Hepatic overproduction of selenoprotein P induces insulin resistance and hyperglycemia in type 2 diabetes2010
- Author(s)
  Misu H, Takamura T, Saito Y, Takahashi K, Kaneko S
- Organizer
  9^<th> International Symposium on Selenium in Biology and Medicine
- Place of Presentation
  京都大学百周年時計台記念館, 京都市、京都(一般演題(口演))
- Year and Date
  2010-06-03
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] Proteasome dysfunction contributes to endoplasmic reticulum stress and insulin resistance in type 2 diabetic liver2010
- Author(s)
  Toshiki Otoda, Hirofumi Misu, Seiichiro Kurita, Miyuki Yamamoto, Tsuguhito Ota, Kosuke R.Shima, Shoichi Iseki, Shigeo.Murata, Keiji Tanaka, Shuichi Kaneko, Toshinari Takamura
- Organizer
  第46回欧州糖尿病学会議(EASD)
- Place of Presentation
  Massanconference andexhibition centre, Stockholm, Sweden(一般演題(ポスター))
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] Molecular pathology underlying insulin resistance in type 2 diabetic liver.2010
- Author(s)
  篁俊成
- Organizer
  Symposium at Kangwon National University "Integrative approaches in the battle against diabetes"
- Place of Presentation
  Kangwon National University, Chuncheon, Korea(招待講演)
- Year and Date
  2010-09-09
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] CCR5 Promotes Adipose Tissue Inflammation and Whole-Body Insulin Resistance.2010
- Author(s)
  Ota T, Kitade H, Sawamoto K, Inoue H, Takamura T, et al.
- Organizer
  8th International Diabetes Federation Western Pacific Region Congress
- Place of Presentation
  BEXCO, Busan, Korea(一般演題(ポスター))
- Year and Date
  2010-10-19
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] 糖尿病臨床医として脂肪肝をどう捉えるか?2010
- Author(s)
  篁俊成
- Organizer
  第44回糖尿病学の進歩
- Place of Presentation
  大阪国際会議場、(大阪)
- Year and Date
  2010-03-06
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] Molecular pathology underlying insulin resistance in type 2 diabetic liver2010
- Author(s)
  篁俊成, 御簾博文, 金子周一
- Organizer
  第53回日本糖尿病学会年次学術集会シンポジウム
- Place of Presentation
  ホテルグランヴィア岡山、岡山市、岡山
- Year and Date
  2010-05-29
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] アンチエイジングを見据えた2型糖尿病の総合的治療戦略2010
- Author(s)
  篁俊成
- Organizer
  Bio Japan 2010
- Place of Presentation
  パシフィコ横浜、横浜市、神奈川(招待講演)
- Year and Date
  2010-09-30
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] Molecular pathology underlying insulin resistance in type 2 diabetic liver2010
- Author(s)
  Takamura T
- Organizer
  Symposium at Kangwon National University "lntegrative approaches in the battle against diabetes"
- Place of Presentation
  Kangwon National University, Chuncheon, Korea(招待講演)
- Year and Date
  2010-09-09
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] Proteasome dysfunction contributes to endoplasmic reticulum stress and insulin resistance in type 2 diabetic liver.2010
- Author(s)
  Otoda T , Misu H, Kurita S, Yamamoto M, Ota T, Shima K, Iseki S, Murata S, Tanaka K, Kaneko S, Takamura T
- Organizer
  第46回欧州糖尿病学会議(EASD),(一般演題(ポスター))
- Place of Presentation
  "Massan" conference and exhibition centre, Stockholm, Sweden
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] スローエイジング糖尿病ケアにおけるインスリン療法のあり方.2010
- Author(s)
  篁俊成
- Organizer
  第25回日本糖尿病合併症学会総会ランチョンセミナー
- Place of Presentation
  びわ湖ホール、大津市、滋賀
- Year and Date
  2010-10-23
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] Nutrition and fitness for prevention / treatment of NAFLD / NASH.2010
- Author(s)
  篁俊成, 金子周一
- Organizer
  The 9th Single Topic Conference NASH 2010
- Place of Presentation
  グランドプリンスホテル高輪、品川、東京
- Year and Date
  2010-11-19
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] 新規インスリン抵抗性誘導ヘパトカインセレノプロテインP同定-セレン含有タンパクによる糖代謝悪化の可能性2009
- Author(s)
  御簾博文, 高山浩昭, 林寛人, 篁俊成
- Organizer
  第82回日本生化学学会、シンポジウム
- Place of Presentation
  神戸ポートアイランド、(神戸)
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] 2型糖尿病患者の病態と酸化的リン酸化遺伝子群の協調的発現異常.2009
- Author(s)
  篁俊成, 御簾博文, 金子周一
- Organizer
  第52回日本糖尿病学会年次学術集会シンポジウム
- Place of Presentation
  大阪国際会議場・リーガロイヤルホテル大阪、大阪市、大阪
- Year and Date
  2009-05-22
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] アンチエイジングを見据えた2型糖尿病の総合的治療戦略.2009
- Author(s)
  篁俊成
- Organizer
  第30回日本臨床薬理学会年会、ランチョンセミナー
- Place of Presentation
  パシフィコ横浜、(横浜)
- Year and Date
  2009-12-05
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] IgG関連疾患の経過中に出現したリンパ球性下垂体炎の男性例2009
- Author(s)
  田治孔明, 赤堀弘, 原田ゆかり, 毛利研祐, 石倉和秀, 竹下有美枝, 御簾博文, 川野充弘, 篁俊成, 林康彦, 林裕, 潰田潤一郎
- Organizer
  第19回臨床内分泌代謝Up date
- Place of Presentation
  東京
- Year and Date
  2009-03-13
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] 2型糖尿病患者における酸化的リン酸化遺伝子群発現異常の意義2009
- Author(s)
  篁俊成, 御簾博文, 金子周一
- Organizer
  第32回日本分子生物学会、ワークショップ
- Place of Presentation
  パシフィコ横浜、(横浜)
- Year and Date
  2009-12-12
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] Clinical and molecular pathology of type 2 diabetic liver.2009
- Author(s)
  篁俊成, et al.
- Organizer
  The 15th Korea-Japan Symposium on Diabetes Mellitus, シンポジウム
- Place of Presentation
  International Convention Center, Jeju, Jeju island, Korea
- Year and Date
  2009-11-20
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] NAFLD-消化器病学と糖尿病学の接点2009
- Author(s)
  篁俊成
- Organizer
  第19回西日本臨床胆汁酸研究会
- Place of Presentation
  リーガロイヤルホテル大阪、(大阪)
- Year and Date
  2009-07-25
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] 肥満に関連したプロテアソーム機能障害は肝臓での小胞体ストレスとインスリン抵抗性を誘導する2009
- Author(s)
  乙田敏城, 御簾博文, 栗田征一郎, 山本美由紀, 太田嗣人, 井関尚一, 村田茂穂, 田中啓二, 金子周一, 篁俊成
- Organizer
  第21回分子糖尿病学シンポジウム、シンポジウム
- Place of Presentation
  和歌山県立医科大学講堂(和歌山)
- Year and Date
  2009-12-12
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] How to motivate your team?医療チームを盛り上げ、磨き上げる臨床研究2009
- Author(s)
  篁俊成
- Organizer
  第9回CRCと臨床試験のあり方を考える会議、シンポジウム
- Place of Presentation
  パシフィコ横浜、(横浜)
- Year and Date
  2009-09-13
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] 臓器特異的インスリン抵抗性が非アルコール性脂肪性肝疾患(NAFLD)患者の肝病理診断にもたらす意義2009
- Author(s)
  加藤健一郎, 篁俊成, 竹下有美枝, 横山将嘉, 濱口えりか, 齋藤麗奈, 堀口美輝, 御簾博文, 太田嗣人, 金子周一
- Organizer
  第24回日本糖尿病合併症学会、ワークショップ
- Place of Presentation
  岡山コンベンションセンター(岡山)
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] 臓器特異的インスリン抵抗性が非アルコール性脂肪性肝疾患(NAFLD)患者の肝病理診断にもたらす意義2009
- Author(s)
  加藤健一郎, 篁俊成, 金子周一
- Organizer
  第13回日本肝臓学会大会、シンポジウム
- Place of Presentation
  国立京都国際会館、(京都)
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] 糖尿病学と肝臓病学の接点としての非アルコール性脂肪性肝疾患2009
- Author(s)
  篁俊成
- Organizer
  第52回日本糖尿病学会年次学術集会,教育講演
- Place of Presentation
  大阪国際会議場、リーガロイヤルホテル大阪、(大阪)
- Year and Date
  2009-05-24
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] 肝臓でのセノプロテインP過剰産生は2型糖尿病患者のインスリン抵抗性の原因となる2009
- Author(s)
  御簾博文, 篁俊成
- Organizer
  第62回日本酸化ストレス学会、シンポジウム
- Place of Presentation
  九州大学医学部百年講堂、(福岡)
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] 2型糖尿病患者の病態と酸化的リン酸化遺伝子群の協調的発現異常2009
- Author(s)
  篁俊成, 御簾博文, 金子周一
- Organizer
  第52回日本糖尿病学会年次学術集会,シンポジウム
- Place of Presentation
  大阪国際会議場、リーガロイヤルホテル大阪、(大阪)
- Year and Date
  2009-05-22
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] Identification of a redox-associated hepatokine that contributes to systemic insulin resistance.2009
- Author(s)
  篁俊成, et al.
- Organizer
  Keystone Symposia on Molecular and Cellular Biology 2009 - Type 2 diabtes and insulin resistance
- Place of Presentation
  Fairmont Banff Springs, Banff, Alberta, Canada(一般演題(ポスター))
- Year and Date
  2009-01-23
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] Adipose tissue derived mesenchymal stem cells are capable to modulate liver inflammation in mouse of non-alcoholic steatohepatitis.2009
- Author(s)
  Seki A, Sakai Y, Tatsumi I, Komura T, Fujinaga H, Honda M, Takamura T, Ochiya T, Kaneko S
- Organizer
  60th American Association for the Study of Liver Diseases, Annual Meeting
- Place of Presentation
  John B. Hynes Convention Center, Boston, (USA)
- Year and Date
  2009-11-03
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] 副腎不全、Cushing徴候、BigIGF2誘発性低血糖を来した副腎癌剖検例2009
- Author(s)
  石倉和秀, 田治孔明, 竹下有美枝, 上山奈央美, 濱口えりか, 御簾博文, 笠原寿郎, 鈴木潮人, 大井章史, 押野谷幸之輔, 今泉範子, 中川淳, 金子周一, 篁俊成
- Organizer
  第19回臨床内分泌代謝Up date
- Place of Presentation
  東京
- Year and Date
  2009-03-14
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] 糖尿病学と肝臓病学の接点としての非アルコール性脂肪性肝疾患.2009
- Author(s)
  篁俊成
- Organizer
  第52回日本糖尿病学会年次学術集会教育講演
- Place of Presentation
  大阪国際会議場・リーガロイヤルホテル大阪、大阪市、大阪
- Year and Date
  2009-05-24
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] Clinical and molecular pathology of type 2 diabetic liver.2009
- Author(s)
  Takamura T, Hirofumi Misu, Shuichi Kaneko
- Organizer
  The 15th Korea-Japan Symposium on Diabetes Mellitus
- Place of Presentation
  International Convention Center Jeju, Jeju, (Korea)
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] Molecular mechanisms underlying fat-induced insulin resistance in the liver2008
- Author(s)
  Toshinari Takamura
- Organizer
  The 17th Korean Diabetes Association Summer Workshop & 2008 Symposium
- Place of Presentation
  Grand Hilton Seoul Hotel, Seoul, Korea(招待講演)
- Year and Date
  2008-08-23
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] 糖尿病新規発症に及ぼす喫煙と腹部肥満との交互作用2008
- Author(s)
  櫻井勝, 三浦克之, 篁俊成, 石崎昌夫, 森河裕子, 城戸照彦, 成瀬優知, 金子周一, 中川秀昭
- Organizer
  第51回日本糖尿病学会
- Place of Presentation
  東京
- Year and Date
  2008-05-24
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] 新規肝臓由来分泌タンパクトHepatokineβ血中濃度は2型糖尿病患者においてHbAlcと相関する2008
- Author(s)
  石倉和秀, 御簾博文, 篁俊成, 長田直人, 清水暁子, 栗田征一郎, 竹下有美枝, 濱口えりか, 安藤仁, 金子周一
- Organizer
  第51回日本糖尿病学会
- Place of Presentation
  東京
- Year and Date
  2008-05-23
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] 肝臓由来分泌タンパクセレノプロティンPは2型糖尿病におけるインスリン抵抗性の原因となる2008
- Author(s)
  御簾博文, 篁俊成, 金子周一
- Organizer
  第20回分子糖尿病学シンポジウム
- Place of Presentation
  神戸
- Year and Date
  2008-12-13
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] Role of mitochondria-derived reactive oxygen species in fat-induced insulin resi stance in liver2008
- Author(s)
  Takamura T, Nagata N, Nakamura S, Takayama H, Sugimori M, Misu H, Kaneko S
- Organizer
  第44回欧州糖尿病学会議(EASD)
- Place of Presentation
  Rome
- Year and Date
  2008-09-08
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] メトホルミンが非アルコール性脂肪肝炎モデルの肝病理を改善した分子背景2008
- Author(s)
  喜多裕樹, 栗田征一郎, 宇野将文, 長田直人, 太田嗣人, 安藤仁, 篁俊成
- Organizer
  第51回日本糖尿病学会
- Place of Presentation
  東京
- Year and Date
  2008-05-22
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] 糖尿病治療チームの指導ノウハウを用いた生活習慣病発症予防システムの構築2008
- Author(s)
  内潟将宏, 山村奈津絵, 竹森千尋, 関軒裕佳, 黒川素江, 河野貴子, 田島奈津美, 八幡陽子, 黒川千佳, 田平裕美子, 東敬一郎, 吉谷久子, 長田美津子, 米田由美, 田治孔明, 石倉和秀, 栗田征一郎, 御簾博文, 安藤仁, 金子周一, 安藤仁, 金子周一, 篁俊成
- Organizer
  第51回日本糖尿病学会
- Place of Presentation
  東京
- Year and Date
  2008-05-23
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] 主観的包括的評価(SGA)は糖尿病入院患者の把握に有用か?2008
- Author(s)
  河野貴子, 黒川千佳, 八幡陽子, 田島奈津美, 黒川素江, 西野喜美子, 関軒裕佳, 竹森千尋, 山下千鶴子, 内潟将宏, 田治孔明, 石倉和秀, 栗田征一郎, 御簾博文, 安藤仁, 金子周一, 篁俊成
- Organizer
  第51回日本糖尿病学会
- Place of Presentation
  東京
- Year and Date
  2008-05-24
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] 抗アレルギー薬トラニラストはラツトNASHモデルのマクロファージ活性化と肝病理進展を阻止する2008
- Author(s)
  栗田征一郎, 篁俊成, 宇野将文, 太田嗣人, 長田直人, 喜多裕樹, 御簾博文, 安藤仁, 全陽, 中沼安二, 金子周一
- Organizer
  第44回日本肝臓学会
- Place of Presentation
  松山
- Year and Date
  2008-06-05
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] Molecular Mechanisms Underlying Fat-induced insulin resistance in the liver2008
- Author(s)
  Takamura T
- Organizer
  第17回 Korea Diabetes Association Summer Workshop&2008 Symposium
- Place of Presentation
  Seoul
- Year and Date
  2008-08-23
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] 健常者および1型、2型糖尿病患者間で異なるグルカゴン分泌制御機構2008
- Author(s)
  上山奈央美, 安藤仁, 櫻井勝, 清水暁子, 加藤健一郎, 栗田征一郎, 御簾博文, 金子周一, 篁俊成
- Organizer
  第51回日本糖尿病学会
- Place of Presentation
  東京
- Year and Date
  2008-05-24
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] インスリン抵抗性で生じる小胞体ストレスはapoB分泌を選択的に阻害し、脂肪肝を促進する2008
- Author(s)
  太田嗣人, 篁俊成, 金子周一, Henry G
- Organizer
  第23回日本糖尿病合併症学会
- Place of Presentation
  東京
- Year and Date
  2008-10-04
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] Role of mitochondria-derived reactive oxygen species in fat-induced insulin resistance in liver.2008
- Author(s)
  篁俊成, et al.
- Organizer
  44th Annual meeting of European Association for the Study of Diabetes (EASD)
- Place of Presentation
  Nuova Fiera di Roma conference and exhibition centre, Rome, Italy(一般演題(ポスター))
- Year and Date
  2008-09-08
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] 「NASHへの挑戦」一創薬の可能性を探る-、肝脂肪化と炎症のリンクーToxic Lipidは何か?2008
- Author(s)
  篁俊成
- Organizer
  第32回ヒューマンサイエンス総合研究セミナー
- Place of Presentation
  東京
- Year and Date
  2008-10-07
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] 2型糖尿病患者における食後インスジン動態、高血糖、脂質異常におよぼすインスリンアスパルトの効果2008
- Author(s)
  清水暁子, 安藤仁, 栗田征一郎, 永野倫子, 長田美津子, 加藤健一郎, 石倉和秀, 田治孔明, 宇野将文, 御簾博文, 吉田知孝, 金子周一, 篁俊成
- Organizer
  第51回日本糖尿病学会
- Place of Presentation
  東京
- Year and Date
  2008-05-24
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] 抗アレルギー薬トラニラストはマクロファージの活性化とインスリン抵抗性を改善する2008
- Author(s)
  栗田征一郎, 宇野将文, 御簾博文, 安藤仁, 太田嗣人, 長田直人, 喜多裕樹, 乙田敏城, 全陽, 金子周一, 篁俊成
- Organizer
  第51回日本糖尿病学会
- Place of Presentation
  東京
- Year and Date
  2008-05-23
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] 末梢分子時計障害と関連する代謝異常の分析2008
- Author(s)
  島孝佑, 安藤仁, 篁俊成, 長田直人, 藤村昭夫, 金子周一
- Organizer
  第51回日本糖尿病学会
- Place of Presentation
  東京
- Year and Date
  2008-05-24
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] 2型糖尿病患者における末梢血白血球の時計遺伝子発現リズム2008
- Author(s)
  安藤仁, 篁俊成, 長田直人, 島孝佑, 藤村昭夫, 金子周一
- Organizer
  第51回日本糖尿病学会
- Place of Presentation
  東京
- Year and Date
  2008-05-23
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] IgG4関連疾患の経過中に出現したリンパ球性下垂体炎の1男性例2008
- Author(s)
  田治孔明, 赤堀弘, 原田ゆかり, 毛利研祐, 石倉和秀, 竹下有美枝, 御簾博文, 篁俊成, 岩戸雅之, 林康彦, 林裕, 潰田潤一郎
- Organizer
  第14回北陸間脳下垂体腫瘍研究会プログラム
- Place of Presentation
  金沢
- Year and Date
  2008-09-06
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] 肝細胞インスリン感受性に及ぼすパルミチン酸とオレイン酸の相互作用2008
- Author(s)
  高山浩昭, 長田直人, 中村誠二, 御簾博文, 太田嗣人, 井上啓, 金子周一, 篁俊成
- Organizer
  第23回日本糖尿病合併症学会
- Place of Presentation
  東京
- Year and Date
  2008-10-04
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] 血清ALT値と脂肪肝は筋でのインスリン抵抗性の指標となり得る2008
- Author(s)
  横山将嘉, 篁俊成, 藤岡正彦, 村本信吾
- Organizer
  第51回日本糖尿病学会
- Place of Presentation
  東京
- Year and Date
  2008-05-23
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] 非アルコール性脂肪肝患者における肝病理像と臓器別インスリン抵抗性2008
- Author(s)
  加藤健一郎, 櫻井勝, 横山将嘉, 清水暁子, 栗田征一郎, 御簾博文, 安藤仁, 金子周一, 篁俊成
- Organizer
  第51回日本糖尿病学会
- Place of Presentation
  東京
- Year and Date
  2008-05-23
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] 末梢血単核球の遺伝子発現プロファイルが糖尿病血管合併症の存在を映し出す可能性2008
- Author(s)
  篁俊成, 中村誠二, 内潟将宏, 清水暁子, 竹下有美枝, 栗田征一郎, 御簾博文, 安藤仁, 松原謙一, 金子周一
- Organizer
  第51回日本糖尿病学会
- Place of Presentation
  東京
- Year and Date
  2008-05-23
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] 過栄養が形成する肝臓の病理と病態2008
- Author(s)
  篁俊成
- Organizer
  第13回静岡健康・長寿学術フォーラム
- Place of Presentation
  静岡
- Year and Date
  2008-11-08
- Data Source
  KAKENHI-PROJECT-20591054
[Presentation] スローエイジングを目指す血糖制御とその向こうにあるもの
- Author(s)
  篁　俊成
- Organizer
  日本循環器予防学会、教育講演
- Place of Presentation
  金沢
- Invited
- Data Source
  KAKENHI-PROJECT-23591301
[Presentation] 糖尿病医療における食事療法の課題
- Author(s)
  篁　俊成
- Organizer
  第56回日本糖尿病学会年次学術集会、シンポジウム
- Place of Presentation
  熊本
- Invited
- Data Source
  KAKENHI-PROJECT-23591301
[Presentation] Organ-specific fat accumulation and insulin resistance among the liver, skeletal muscle and adipose tissue in people with nonalcoholic fatty liver disease.
- Author(s)
  Takamura T, Kato K-I, Misu H, Takeshita Y, Kaneko S:
- Organizer
  49th Annual Meeting of the European Association for the Study of Diabetes (EASD)
- Place of Presentation
  Barcelona(Spain)
- Data Source
  KAKENHI-PROJECT-23591301

1. HONDA Masao (00272980)

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2. KANEKO Shuichi (60185923)

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3. YONEDA Makoto (70270551)

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10. 小野政徳 (70348712)

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13. NAKANUMA Yasuni (10115256)

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14. MURATA Shigeo (20344070)

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15. ISEKI Shoichi (50167251)

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16. IKAWA Masamichi (60444212)

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17. 中本安成 (40293352)

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takamura toshinari 篁 俊成

TAKAMURA Toshinari 篁 俊成

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Selenoprotein P protein and mRNA functions in the diabetes pathologyPrincipal Investigator

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Functional analyses of selenoprotein P mRNA-binding proteins in brown/white adipose tissuesPrincipal Investigator

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連続肝生検アプローチによる糖尿病性脂肪肝炎のバイオマーカー探索Principal Investigator

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Development of exercise-enhancing therapy targeting the liver-skeletal muscle networkPrincipal Investigator

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Perturbation of redox balance in pathophysiology of diabetesPrincipal Investigator

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roles of intracellular proteolytic systems in maintaining energy metabolism homeostasisPrincipal Investigator

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takamura toshinari 篁俊成

TAKAMURA Toshinari 篁俊成

[Book] 内科学第12版2022

[Book] 内科学第12版2022