TAKAHASHI Kazuhisa 高橋和久

Researcher Number	80245711
Other IDs	https://orcid.org/0000-0001-5749-4118
Affiliation (Current)	2025: 順天堂大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2007 – 2024: Juntendo University, 医学部, 教授 2010: 順天堂大学, 呼吸器内科, 教授 2007: 順天堂大学, 呼吸器内科, 教授 2005: Juntendo University, Respiratory Medicine, Professor, 医学部, 教授 2002 – 2004: UNTENDO UNIVERSITY, SCHOOL OF MEDICINE, ASSISTANT PROFESSOR, 医学部, 助教授 1999 – 2002: Juntendo University, Respiratory Medicine, Assistant Professor, 医学部, 講師 1998: 順天堂大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Respiratory organ internal medicine / Basic Section 53030:Respiratory medicine-related / Respiratory organ internal medicine Except Principal Investigator Basic Section 53030:Respiratory medicine-related / Respiratory organ internal medicine / Respiratory organ internal medicine / Basic Section 50020:Tumor diagnostics and therapeutics-related / Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields / Pediatrics
Keywords	Principal Investigator 肺癌 / オステオポンチン / 中皮腫 / CD44 / 非小細胞肺癌 / VEGF / エンドスタチン / Gefitinib / 癌幹細胞 / 抗癌剤耐性 … More / 抗がん剤耐性 / エピジェネティクス / シングルセル解析 / 腫瘍内不均一性 / 新規治療標的 / 遺伝子解析 / スクリーニング解析 / チロシンキナーゼ / 遺伝子異常 / 胸腺癌 / Gefitinib耐性 / 肺癌幹細胞 / EGFR-TKI耐性 / 静止期 / 薬剤耐性 / Mice / Recombinant protein / Anti-tumor effect / Integrin receptor / Lung cancer / Endostatin / 受容体 / マウス / 融合蛋白 / 抗腫瘍効果 / インテグリン受容体 / ANGIOGENESIS / LUNG CANCER / ENDOSTATIN / OSTEOPONTIN / 転移 / 浸潤 / 血管新生 / microRNA / ZEB1 / 幹細胞 / 耐性 / EMT / 低酸素 / EGFR-TKI / EGFR-TKI 耐性 / 細胞外マトリックス / ヒアルロン酸 / 抗癌剤多剤耐性 / 悪性中皮腫 / MRP / 抗がん剤 / 呼吸器病学 / アイソフォーム / マクロファージ / 細胞障害性 … More Except Principal Investigator SMP30 / エピジェネティクス / Emphysema / COPD / 肺気腫 / シングルセル解析 / 薬剤耐性 / 肺癌 / 細胞老化 / 非小細胞肺癌 / Keap1-Nrf2経路 / 酸化ストレス応答経路 / 小細胞肺癌 / 小細胞肺がん / 肺がん / 中皮腫 / 気道炎症 / 加齢 / マウス / ブレオマイシン / 上皮間葉転換 / 喫煙 / スクリーニング / バイオマーカー / ゲノム構造多型 / スプライシング異常 / 治療標的 / シングルセルATAC-seq / シングルセルRNA-seq / 腫瘍内不均一性 / 胸部悪性腫瘍 / 免疫チェックポイント阻害薬 / 予測 / 効果予測 / 機械学習 / 糖鎖分子 / 血中循環腫瘍細胞 / テロメスキャン / 循環腫瘍細胞 / ユビキチン‐プロテオソーム系 / 阻害剤 / 細胞周期 / SKP2 / ユビキチン‐プロテオソーム経路 / スプライシング / 酸化ストレス経路 / 抗癌剤耐性 / 呼吸器病学 / 間質性肺炎 / マウスモデル / TGFβ / 急性肺障害 / 肺胞上皮細胞 / 間質性肺疾患 / 薬剤性肺障害 / 分子標的 / 新規治療標的 / 遺伝子解析 / スクリーニング解析 / チロシンキナーゼ / 遺伝子異常 / 分子標的治療薬 / 癌 / ヒストンメチル化酵素 / ヒストン脱メチル化酵素 / 中皮腫久 / LSD1 / ヒストン脱メチル化 / ヒストンメチル化 / ヒストン修飾 / エピジェンティクス / 画像診断 / PET / mesothelin / Erc / 腫瘍診断 / 悪性中皮腫 / アスベスト / Senescence-accelerated mouse / Aging / Protein modification / Cigarette smoke exposure / Airway Inflammation / 粘液細胞 / ニトロチロシン / 慢性喫煙曝露 / 炎症性サイトカイン / senescence-accelerated mouse / 分子修飾 / 慢性喫煙暴露 / bronchial inflammation / smoke exposure / apoptosis / bronchial epithelial cells / Knockout mice / Ageing / アポトーシス / 気道上皮細胞 / ノックアウトマウス / extra cellular matrix / smoking exposure / Fawn-hooded rat / Lung mechanics / MMP / レチノイド / 細胞外マトリックス / 喫煙曝露 / FHR / 換気力学 / 慢性閉塞性肺疾患 / mouse / macrophage / osteopontin / nitric oxide / ARDS / 肺障害 / マクロファージ / オステオポンチン / 一酸化窒素 / 成人呼吸促迫症候群 / 肺線維症マウスモデル / 肺胞上皮 / 特発性肺線維症 / オッズ比 / 生活習慣病検診 / メタボリック症候群 / 肥満 / 妊娠中喫煙 / 動脈硬化 / 生活習慣病 / 禁煙 / 受動喫煙検診 / 発がん / 酸化ストレス / イソプロスタン / コチニン / 受動喫煙 Less

薬剤耐性クローンに着目した腫瘍内不均一性と薬剤耐性原理の解明
- Principal Investigator
  
  田島健
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Juntendo University
エピジェネティクスの再構成の追跡による老化細胞の分類構築と新規治療法開発への挑戦
- Principal Investigator
  
  田島健
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Juntendo University
肺癌における酸化ストレス応答系の新規破綻機序の解明と標的治療の探索
- Principal Investigator
  
  光石陽一郎
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Juntendo University
Developing a model to predict response to immune checkpoint inhibitor using machine learning
- Principal Investigator
  
  宿谷威仁
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Juntendo University
テロメスキャンによる高感度血中循環腫瘍細胞測定の実用化臨床研究
- Principal Investigator
  
  十合晋作
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Juntendo University
肺癌における糖鎖分子を標的としたEGFR-TKI耐性克服の試み
- Principal Investigator
  
  高橋史行
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Juntendo University
中皮腫における細胞系譜構築による新規治療法の探究と臨床応用Principal Investigator
- Principal Investigator
  
  高橋和久
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Juntendo University
小細胞肺癌における酸化ストレス応答系の破綻機序の解明
- Principal Investigator
  
  光石陽一郎
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Juntendo University
Exploration of novel therapies for small cell lung cancer by targeting ubiquitination to induce cell death and senescence
- Principal Investigator
  
  Tajima Ken
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Juntendo University
analysis of novel transcript variant of tyrosine kinase gene in thymic carcinomaPrincipal Investigator
- Principal Investigator
  
  Takahashi Kazuhisa
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Juntendo University
analysis of novel transcript variant of tyrosine kinase gene in small cell lung cancer using the NanoString nCounter
- Principal Investigator
  
  Takahashi Fumiyuki
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Juntendo University
The basic research of treatment for drug-induced lung injury focusing on epithelial-mesenchymal transition
- Principal Investigator
  
  KATO MOTOYASU
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Juntendo University
Inactivation of tumor suppressor by histone methylation in lung cancer
- Principal Investigator
  
  Tajima Ken
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Juntendo University
Role of quiescent cancer stem cells in the gefitinib resistance in EGFR mutation positive non-small cell lung cancerPrincipal Investigator
- Principal Investigator
  
  Takahashi Kazuhisa
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Juntendo University
EMT inhibitor for the treatment of idiopathic pulmonary fibrosis
- Principal Investigator
  
  Takahashi Fumiyuki
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Juntendo University
Role of hypoxia and cancer stem cells in the resistance to EGFR-TKI in non-small cell lung cancerPrincipal Investigator
- Principal Investigator
  
  Takahashi Kazuhisa
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Juntendo University
Mechanism of multidrug resistance in mesothelioma cells, and the treatment strategy targeting CD44Principal Investigator
- Principal Investigator
  
  TAKAHASHI Kazuhisa
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Juntendo University
Role of osteopontin in the pathogenesis of malignant mesotheliomaPrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Kazuhisa
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Juntendo University
Investigation regarding with the actual situation of passive smoking by using screening methob
- Principal Investigator
  
  INO Toshihiro
- Project Period (FY)
  2007 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Gumma Paz College
アスベスト暴露に伴う悪性中皮腫の早期診断法の開発
- Principal Investigator
  
  辻井博彦
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Special Purposes
- Research Institution
  National Institute of Radiological Sciences
Enhanced suppression of in vivo tumorigenecity of lung cancer by molecular engineered anti-angiogenic agentsPrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Kazuhisa
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  JUNTENDO UNIVERSITY
Analysis of airway inflammation and remodeling induced by chronic cigarette smoke exposure in mice lungs.
- Principal Investigator
  
  FUKUCHI Yoshinosuke
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  JUNTENDO UNIVERSITY
Cigarette smoke-induced lung pathology in SMP30 knockout mice
- Principal Investigator
  
  FUKUCHI Yoshinosuke
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  JUNTENDO UNIVERSITY
INHIBITION OF LUNG CANCER INVASION AND METASTASIS BY NOVEL ANGIOGENESIS INHIBITORSPrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Kazuhisa
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  JUNTENDO UNIVERSITY
非小細胞肺癌の浸潤、転移成立におけるCD44の関与Principal Investigator
- Principal Investigator
  
  高橋和久
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Juntendo University
Molecular and genetic studies on patho genesis and patho plrysiolegy of emphysema
- Principal Investigator
  
  FUKUCHI Yoshinosuke
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  JUNTENDO UNIVERSITY
Involvement of nitric oxide in the pathogenesis of adult respiratory syndrome (ARDS) and the regulation of ARDS by osteopontin
- Principal Investigator
  
  SATO Kazuhiko
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Juntendo University

[Journal Article] Early Detection of Therapeutic Benefit from PD-1/PD-L1 Blockade in Advanced Lung Cancer by Monitoring Cachexia-Related Circulating Cytokines2023
- Author(s)
  Xu Shiting、Miura Keita、Shukuya Takehito、Harada Sonoko、Fujioka Masahiro、Winardi Wira、Shimamura Shoko、Kurokawa Kana、Sumiyoshi Issei、Miyawaki Taichi、Asao Tetsuhiko、Mitsuishi Yoichiro、Tajima Ken、Takahashi Fumiyuki、Hayashi Takuo、Harada Norihiro、Takahashi Kazuhisa
- Journal Title
  
  Cancers
  
  Volume: 15 Issue: 4 Pages: 1170-1170
- DOI
  10.3390/cancers15041170
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08524, KAKENHI-PROJECT-19K23978, KAKENHI-PROJECT-21K08187
[Journal Article] CALML5 is a novel diagnostic marker for differentiating thymic squamous cell carcinoma from type B3 thymoma.2023
- Author(s)
  Kanamori K, Suina K, Shukuya T, Takahashi F, Hayashi T, Hara K, Saito T, Mitsuishi Y, Shimamura SS, Winardi W, Tajima K, Ko R, Mimori T, Asao T, Itoh M, Kawaji H, Suehara Y, Takamochi K, Suzuki K, Takahashi K.
- Journal Title
  
  Thoracic Cancer
  
  Volume: 14 Issue: 12 Pages: 1089-1097
- DOI
  10.1111/1759-7714.14853
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08187, KAKENHI-PROJECT-19K22694, KAKENHI-PROJECT-19H03789
[Journal Article] Clinical relevance of PD-L2 expression in surgically resected lung adenocarcinoma.2022
- Author(s)
  Takamochi K, Hara K, Hayashi T, Kohsaka S, Takahashi F, Suehara Y, Shimokawa M, Suzuki K.
- Journal Title
  
  Lung Cancer
  
  Volume: 168 Pages: 50-58
- DOI
  10.1016/j.lungcan.2022.04.011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08187, KAKENHI-PROJECT-19K22694, KAKENHI-PROJECT-21H02795, KAKENHI-PROJECT-19H03789
[Journal Article] A Randomized Phase 2 Study of 5-Aminolevulinic Acid Hydrochloride and Sodium Ferrous Citrate for the Prevention of Nephrotoxicity Induced by Cisplatin-Based Chemotherapy of Lung Cancer2022
- Author(s)
  Kawamura Kodai,Matsushima Hidekazu,Sakai Hiroshi,Iwashima Akira,Nakamura Sukeyuki,Kojima Tohru,Sasaki Shinichi,Shigenaga Takehiko,Natsume Ichiro,Sasaki Takaaki,Ohsaki Yoshinobu,Iwanaga Kentaro,Nishi Koichi,Mitsuishi Yoichiro,Taniguchi Hirokazu,Sato Kazuhiro,Yamauchi Mitsugu,Nakajima Motowo,Takahashi Kazuhisa
- Journal Title
  
  Oncology
  
  Volume: 100 Issue: 11 Pages: 620-632
- DOI
  10.1159/000526977
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08524
[Journal Article] Survival past five years with advanced, EGFR-mutated or ALK-rearranged non-small cell lung cancer?is there a “tail plateau” in the survival curve of these patients?2022
- Author(s)
  Shimamura Shoko Sonobe、Shukuya Takehito、Asao Tetsuhiko、Hayakawa Daisuke、Kurokawa Kana、Xu Shiting、Miura Keita、Mitsuishi Yoichiro、Tajima Ken、Shibayama Rina、Shimada Naoko、Takahashi Fumiyuki、Takahashi Kazuhisa
- Journal Title
  
  BMC Cancer
  
  Volume: 22 Issue: 1 Pages: 323-323
- DOI
  10.1186/s12885-022-09421-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08524, KAKENHI-PROJECT-21K08187
[Journal Article] Clinical characteristics of adrenal insufficiency induced by pembrolizumab in non‐small‐cell lung cancer2022
- Author(s)
  Kurokawa Kana、Mitsuishi Yoichiro、Shimada Naoko、Ito Naoaki、Ogiwara Misa、Miura Keita、Asao Tetsuhiko、Ko Ryo、Shukuya Takehito、Shibayama Rina、Goto Hiromasa、Takahashi Kazuhisa
- Journal Title
  
  Thoracic Cancer
  
  Volume: 14 Issue: 5 Pages: 442-449
- DOI
  10.1111/1759-7714.14761
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08524
[Journal Article] Association between the efficacy and immune-related adverse events of pembrolizumab and chemotherapy in non-small cell lung cancer patients: a retrospective study2022
- Author(s)
  Kurokawa Kana、Mitsuishi Yoichiro、Shimada Naoko、Kawakami Yuta、Miura Keita、Miyawaki Taichi、Asao Tetsuhiko、Ko Ryo、Shukuya Takehito、Shibayama Rina、Nojiri Shuko、Takahashi Kazuhisa
- Journal Title
  
  BMC Cancer
  
  Volume: 22 Issue: 1 Pages: 1047-1047
- DOI
  10.1186/s12885-022-10133-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08524
[Journal Article] Distinct properties of pure- and mixed-type high-grade fetal lung adenocarcinomas by genetic profiling and transcription factor expression.2022
- Author(s)
  Kishikawa S, Hayashi T, Saito T, Takamochi K, Sasa K, Suehara Y, Takahashi F, Sasahara N, Kohsaka S, Suzuki K, Yao T
- Journal Title
  
  Virchows Arch
  
  Volume: 480 Issue: 3 Pages: 609-619
- DOI
  10.1007/s00428-021-03247-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07469, KAKENHI-PROJECT-21H02795, KAKENHI-PROJECT-21K08187
[Journal Article] A Novel Therapeutic Strategy Targeting the Mesenchymal Phenotype of Malignant Pleural Mesothelioma by Suppressing LSD12021
- Author(s)
  Wirawan Aditya、Tajima Ken、Takahashi Fumiyuki、Mitsuishi Yoichiro、Winardi Wira、Hidayat Moulid、Hayakawa Daisuke、Matsumoto Naohisa、Izumi Kenta、Asao Tetsuhiko、Ko Ryo、Shimada Naoko、Takamochi Kazuya、Suzuki Kenji、Abe Masaaki、Hino Okio、Sekido Yoshitaka、Takahashi Kazuhisa
- Journal Title
  
  Molecular Cancer Research
  
  Volume: 20 Issue: 1 Pages: 127-138
- DOI
  10.1158/1541-7786.mcr-21-0230
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03527, KAKENHI-PROJECT-20K08524, KAKENHI-PROJECT-21K08187
[Journal Article] Zinc‐finger E‐box‐binding homeobox 1 (ZEB1) plays a crucial role in the maintenance of lung cancer stem cells resistant to gefitinib2021
- Author(s)
  Nurwidya Fariz et al.
- Journal Title
  
  Thoracic Cancer
  
  Volume: in press Issue: 10 Pages: 1536-1548
- DOI
  10.1111/1759-7714.13937
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07092, KAKENHI-PROJECT-18K08185, KAKENHI-PROJECT-21K08187
[Journal Article] Highly sensitive fusion detection using plasma cell-free RNA in non-small-cell lung cancers.2021
- Author(s)
  Hasegawa N, Kohsaka S, Kurokawa K, Shinno Y, Takeda Nakamura I, Ueno T, Kojima S, Kawazu M, Suehara Y, Ishijima M, Goto Y, Kojima Y, Yonemori K, Hayashi T, Saito T, Shukuya T, Takahashi F, Takahashi K, Mano H.
- Journal Title
  
  Cancer Sci
  
  Volume: 112 Issue: 10 Pages: 4393-4403
- DOI
  10.1111/cas.15084
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08185, KAKENHI-PROJECT-21H02772, KAKENHI-PROJECT-21H02795, KAKENHI-PROJECT-21K08187, KAKENHI-PROJECT-21K12117, KAKENHI-PROJECT-19K22694, KAKENHI-PROJECT-21K20846, KAKENHI-PROJECT-19H03789
[Journal Article] Comprehensive functional evaluation of variants of fibroblast growth factor receptor genes in cancer.2021
- Author(s)
  Takeda Nakamura I, Kohsaka S, Ikegami M, Ueno T, Li K, Beyett T, Koyama T, Shimizu T, Yamamoto N, Takahashi F, Takahashi K, Eck M, Mano H.
- Journal Title
  
  NPJ Precision Oncology
  
  Volume: 16 Issue: 1 Pages: 66-66
- DOI
  10.1038/s41698-021-00204-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08185, KAKENHI-PROJECT-21H02795, KAKENHI-PROJECT-21K08187, KAKENHI-PROJECT-21K12117
[Journal Article] Development of an optimal protocol for molecular profiling of tumor cells in pleural effusions at single-cell level2021
- Author(s)
  Takeda Nakamura I, Ikegami M, Hasegawa N, Hayashi T, Ueno T, Kawazu M, Yagishita S, Goto Y, Shinno Y, Kojima Y, Takamochi K, Takahashi F, Takahashi K, Mano H, Kohsaka S
- Journal Title
  
  Cancer Sci
  
  Volume: － Issue: 5 Pages: 2006-2019
- DOI
  10.1111/cas.14821
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02677, KAKENHI-PROJECT-18K08185, KAKENHI-PROJECT-21H02772, KAKENHI-PROJECT-21H02795, KAKENHI-PROJECT-21K08187, KAKENHI-PROJECT-21K12117
[Journal Article] Activation of insulin-like growth factor-1 receptor confers acquired resistance to osimertinib in non-small cell lung cancer with EGFR T790M mutation2020
- Author(s)
  Hayakawa D, Takahashi F, Mitsuishi Y, Tajima K, Hidayat M, Winardi W, Ihara H, Kanamori K, Matsumoto N, Asao T, Ko R, Shukuya T, Takamochi K, Hayashi T, Suehara Y, Takeda Nakamura I, Ueno T, Kohsaka S, Mano H, Takahashi K
- Journal Title
  
  Thorac Cancer
  
  Volume: 11 Issue: 1 Pages: 140-149
- DOI
  10.1111/1759-7714.13255
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02677, KAKENHI-PROJECT-17K07250, KAKENHI-PROJECT-18K08185, KAKENHI-PROJECT-19K22694, KAKENHI-PROJECT-19H03789, KAKENHI-PROJECT-17K09669
[Journal Article] Clinicopathological characteristics of lung adenocarcinoma with compound EGFR mutations.2020
- Author(s)
  Hayashi T, Kohsaka S, Takamochi K, Hara K, Kishikawa S, Sano K, Takahashi F, Suehara Y, Saito T, Takahashi K, Suzuki K, Yao T.
- Journal Title
  
  Human Pathology
  
  Volume: 14 Pages: 42-51
- DOI
  10.1016/j.humpath.2020.07.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08185, KAKENHI-PROJECT-19K22694, KAKENHI-PROJECT-18H02677, KAKENHI-PROJECT-19H03789, KAKENHI-PROJECT-17K09669, KAKENHI-PROJECT-19K07469
[Journal Article] Identification of Novel CD74-NRG2α Fusion From Comprehensive Profiling of Lung Adenocarcinoma in Japanese Never or Light Smokers2020
- Author(s)
  Kohsaka S, Hayashi T, Nagano M, Ueno T, Kojima S, Kawazu M, Shiraishi Y, Kishikawa S, Suehara Y, Takahashi F, Takahashi K, Suzuki K, Takamochi K, Mano H
- Journal Title
  
  Journal of Thoracic Oncology
  
  Volume: － Issue: 6 Pages: 30098-8
- DOI
  10.1016/j.jtho.2020.01.021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02677, KAKENHI-PROJECT-19H03789, KAKENHI-PROJECT-17K07250, KAKENHI-PROJECT-18K08185, KAKENHI-PROJECT-19K22694, KAKENHI-PROJECT-17K09669
[Journal Article] Comprehensive assay for the molecular profiling of cancer by target enrichment from formalin‐fixed paraffin‐embedded specimens2019
- Author(s)
  Kohsaka Shinji、Tatsuno Kenji、Ueno Toshihide、et al.
- Journal Title
  
  Cancer Science
  
  Volume: 110 Issue: 4 Pages: 1464-1479
- DOI
  10.1111/cas.13968
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07250, KAKENHI-PROJECT-18K09249, KAKENHI-PROJECT-15KK0353, KAKENHI-PROJECT-15H04964, KAKENHI-PROJECT-15K09230, KAKENHI-PROJECT-16K15670, KAKENHI-PROJECT-17K19608, KAKENHI-PROJECT-17K08730, KAKENHI-PROJECT-17K09669, KAKENHI-PROJECT-18K08185, KAKENHI-PROJECT-17K07195, KAKENHI-PROJECT-19H03715, KAKENHI-PROJECT-18H02677
[Journal Article] Next-generation sequencing analysis for gastric adenocarcinoma with enteroblastic differentiation: emphasis on the relationship with hepatoid adenocarcinoma.2018
- Author(s)
  1.Akazawa Y, Saito T, Hayashi T, Yanai Y, Tsuyama S, Akaike K, Suehara Y, Takahashi F, Takamochi K, Ueyama H, Murakami T, Watanabe S, Nagahara A, Yao T.
- Journal Title
  
  Hum Pathol
  
  Volume: 78 Pages: 79-88
- DOI
  10.1016/j.humpath.2018.04.022
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08704, KAKENHI-PROJECT-17K09669, KAKENHI-PROJECT-15KK0353, KAKENHI-PROJECT-15H04964, KAKENHI-PROJECT-16K15670
[Journal Article] Prognostic Factors and Efficacy of First-Line Chemotherapy in Patients with Advanced Thymic Carcinoma2018
- Author(s)
  Ko R, Shukuya T, Okuma Y, Tateishi K, Imai H, Iwasawa S, Miyauchi E, Fujiwara A, Sugiyama T, Azuma K, Muraki K, Yamasaki M, Tanaka H, Takashima Y, Soda S, Ishimoto O, Koyama N, Morita S, Kobayashi K, Nukiwa T, Takahashi K; North East Japan Study Group.
- Journal Title
  
  Oncologist
  
  Volume: unknown Issue: 10 Pages: 1210-1217
- DOI
  10.1634/theoncologist.2017-0586
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09562, KAKENHI-PROJECT-17K09671, KAKENHI-PROJECT-18K08185, KAKENHI-PROJECT-15K09230
[Journal Article] Proteomic signatures corresponding to the SS18/SSX fusion gene in synovial sarcoma.2018
- Author(s)
  Ishii M, Suehara Y, Sano K, Kohsaka S, Hayashi T, Kazuno S, Akaike K, Mukaihara K, Kim Y, Okubo T, Takamochi K, Takahashi F, Kaneko K, Saito T.
- Journal Title
  
  Oncotarget
  
  Volume: 9(101) Issue: 101 Pages: 37509-37519
- DOI
  10.18632/oncotarget.26493
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08730, KAKENHI-PROJECT-17K09669, KAKENHI-PROJECT-17K10987, KAKENHI-PROJECT-18K15329, KAKENHI-PROJECT-15KK0353, KAKENHI-PROJECT-15H04964, KAKENHI-PROJECT-16K15670, KAKENHI-PROJECT-16K20070, KAKENHI-PROJECT-18H02677
[Journal Article] EGFR promotes glioma progression by regulating xCT and GluN2B-containing NMDA receptor signaling.2018
- Author(s)
  Suina K, Tsuchihashi K, Yamasaki J, Kamenori S, Shintani S, Hirata Y, Okazaki S, Sampetrean O, Baba E, Akashi K, Takahashi F, Takahashi K, Saya H, Nagano O.
- Journal Title
  
  Cancer Science
  
  Volume: 109 Issue: 12 Pages: 3874-3882
- DOI
  10.1111/cas.13826
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09669, KAKENHI-PROJECT-18K08185, KAKENHI-PROJECT-18K15215, KAKENHI-PROJECT-18K15223, KAKENHI-PROJECT-17H01401, KAKENHI-PROJECT-17H03583, KAKENHI-PROJECT-15K09230, KAKENHI-PROJECT-16K07124, KAKENHI-PROJECT-18J14396
[Journal Article] Non-small cell lung carcinoma with diffuse co-expression of thyroid transcription factor-1 and ΔNp63/p402018
- Author(s)
  Hayashi Takuo、Takamochi Kazuya、Yanai Yuka、Mitani Keiko、Tomita Hisashi、Mogushi Kaoru、Suehara Yoshiyuki、Takahashi Fumiyuki、Suzuki Kenji、Saito Tsuyoshi、Yao Takashi
- Journal Title
  
  Human Pathology
  
  Volume: S0046-8177 Pages: 30037-6
- DOI
  10.1016/j.humpath.2018.01.023
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09230, KAKENHI-PROJECT-17K09669, KAKENHI-PROJECT-16K15670, KAKENHI-PROJECT-15KK0353, KAKENHI-PROJECT-15H04964, KAKENHI-PROJECT-26461200, KAKENHI-PROJECT-16K10476, KAKENHI-PROJECT-18K08798
[Journal Article] Comparison of the Analytical Performance Between cobas EGFR Assay and PCR-Clamp Method in the Detection of EGFR Mutations in Japanese Non-Small Cell Lung Cancer Patients2017
- Author(s)
  Ai Tomohiko、Yuri Maiko、Tabe Yoko、Kakimoto Atsushi、Morishita Soji、Tsuchiya Koji、Takamochi Kazuya、Kodama Yuzo、Takahashi Fumiyuki、Shigeki Misawa、Horii Takashi、Suzuki Kenji、Takahashi Kazuhisa、Miida Takashi、Ohsaka Akimichi
- Journal Title
  
  Clinical Laboratory
  
  Volume: 63 Issue: 05+06/2017 Pages: 1021-1026
- DOI
  10.7754/clin.lab.2017.161223
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09230, KAKENHI-PROJECT-15K08624
[Journal Article] LSD1/KDM1 isoform LSD1+8a contributes to neural differentiation in small cell lung cancer2017
- Author(s)
  Jotatsu, T., Yagishita, S., Tajima, K., Takahashi, F., Mogushi, K., Hidayat, M., Wirawan, A., Ko, R., Kanemaru, R., Shimada, N., Mitani, K., Saito, T., Takamochi, K., Suzuki, K., Kohsaka, S., Kojima, S., Mukae, H., Yatera, K., and Takahashi, K.
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: ９ Pages: 86-94
- DOI
  10.1016/j.bbrep.2016.11.015
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K09586, KAKENHI-PROJECT-17K09669, KAKENHI-PROJECT-16K15625
[Journal Article] A method of high-throughput functional evaluation of EGFR gene variants of unknown significance in cancer2017
- Author(s)
  Kohsaka Shinji、Nagano Masaaki、Ueno Toshihide、Suehara Yoshiyuki、Hayashi Takuo、Shimada Naoko、Takahashi Kazuhisa、Suzuki Kenji、Takamochi Kazuya、Takahashi Fumiyuki、Mano Hiroyuki
- Journal Title
  
  Science Translational Medicine
  
  Volume: 9 Issue: 416 Pages: 6566-6566
- DOI
  10.1126/scitranslmed.aan6566
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09230, KAKENHI-PROJECT-16K10691, KAKENHI-PROJECT-17K07250, KAKENHI-PROJECT-17K09669, KAKENHI-PROJECT-16K15670, KAKENHI-PROJECT-15KK0353, KAKENHI-PROJECT-15H04964, KAKENHI-PROJECT-26461200
[Journal Article] Surfactant protein-D predicts prognosis of interstitial lung disease induced by anticancer agents in advanced lung cancer: a case control study2017
- Author(s)
  Nakamura Kota、Kato Motoyasu、Shukuya Takehito、Mori Keita、Sekimoto Yasuhito、Ihara Hiroaki、Kanemaru Ryota、Ko Ryo、Shibayama Rina、Tajima Ken、Koyama Ryo、Shimada Naoko、Nagashima Osamu、Takahashi Fumiyuki、Sasaki Shinichi、Takahashi Kazuhisa
- Journal Title
  
  BMC Cancer
  
  Volume: 17 Issue: 1 Pages: 302-302
- DOI
  10.1186/s12885-017-3285-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461200
[Journal Article] DNA mismatch repair deficiency in surgically resected lung adenocarcinoma: Microsatellite instability analysis using the Promega panel2017
- Author(s)
  Takamochi Kazuya、Takahashi Fumiyuki、Suehara Yoshiyuki、Sato Eiichi、Kohsaka Shinji、Hayashi Takuo、Kitano Shigehisa、Uneno Toshihide、Kojima Shinya、Takeuchi Kengo、Mano Hiroyuki、Suzuki Kenji
- Journal Title
  
  Lung cancer
  
  Volume: 110 Pages: 26-31
- DOI
  10.1016/j.lungcan.2017.05.016
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09230, KAKENHI-PROJECT-16K10691, KAKENHI-PROJECT-17K09669, KAKENHI-PROJECT-16K15670, KAKENHI-PROJECT-15KK0353, KAKENHI-PROJECT-15H04964, KAKENHI-PROJECT-26461200
[Journal Article] Haploinsufficiency of the folliculin gene leads to impaired functions of lung fibroblasts in patients with Birt-Hogg-Dube syndrome.2016
- Author(s)
  Hoshika Y, Takahashi F, Takahashi K, et al.
- Journal Title
  
  Physiological Reports
  
  Volume: 4 Pages: 13025-13025
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K09230
[Journal Article] Cerebral infarction in advanced non-small cell lung cancer.2016
- Author(s)
  Kato M, Takahashi F, Takahashi K, et al.
- Journal Title
  
  BMC Cancer
  
  Volume: 10 Issue: 1 Pages: 203-203
- DOI
  10.1186/s12885-016-2233-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591176, KAKENHI-PROJECT-15K09230, KAKENHI-PROJECT-26461200
[Journal Article] Haploinsufficiency of the folliculin gene leads to impaired functions of lung fibroblasts in patients with Birt-Hogg-Dube syndrome.2016
- Author(s)
  Hoshika Y, Takahashi F, Takahashi K, et al.
- Journal Title
  
  Physiological Reports
  
  Volume: 4 Pages: 13025-13025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461200
[Journal Article] Oct4 plays a crucial role in the maintenance of gefitinib-resistant lung cancer stem cells.2016
- Author(s)
  Kobayashi I, Takahashi F, Nurwidya F, Nara T, Hashimoto M, Murakami A,
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: in press Issue: 1 Pages: 125-132
- DOI
  10.1016/j.bbrc.2016.03.064
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08452, KAKENHI-PROJECT-26461672, KAKENHI-PROJECT-26501007, KAKENHI-PROJECT-24591176, KAKENHI-PROJECT-25670205, KAKENHI-PROJECT-24390102, KAKENHI-PROJECT-15K09230, KAKENHI-PROJECT-26461200, KAKENHI-PROJECT-16K15268
[Journal Article] Chemotherapy induced microRNA-125/HER2 pathway as a novel therapeutic target for trastuzumab-mediated cellular cytotoxicity in small-cell lung cancer.2015
- Author(s)
  Yagishita S, Fujita Y, Kitazono S, Nakadate Y, Sawada T, Kitamura Y, Shimoyama T, Takahashi F, Takahashi K, Tamura T, Koizumi F.
- Journal Title
  
  Mol Cancer Ther
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461200
[Journal Article] Chemotherapy induced microRNA-125/HER2 pathway as a novel therapeutic target for trastuzumab-mediated cellular cytotoxicity in small-cell lung cancer.2015
- Author(s)
  Yagishita S, Fujita Y, Kitazono S, Nakadate Y, Sawada T, Kitamura Y, Shimoyama T, Takahashi F, Takahashi K, Tamura T, Koizumi F.
- Journal Title
  
  Mol Cancer Ther
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591176
[Journal Article] Chemotherapy induced microRNA-125/HER2 pathway as a novel therapeutic target for trastuzumab-mediated cellular cytotoxicity in small-cell lung cancer.2015
- Author(s)
  Yagishita S, Takahashi F, Takahashi K, et al.
- Journal Title
  
  Mol Cancer Ther
  
  Volume: 14 Issue: 6 Pages: 1414-23
- DOI
  10.1158/1535-7163.mct-14-0625
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09230, KAKENHI-PROJECT-26461200, KAKENHI-PROJECT-24591176
[Journal Article] Tocilizumab, a proposed therapy for the cachexia of interleukin 6-expressing lung cancer2014
- Author(s)
  Ando K, Takahashi F, Kato M, Kaneko N, Doi T, Ohe Y, Koizumi F, Nishio K, Takahashi K.
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 7 Pages: e102436-e102436
- DOI
  10.1371/journal.pone.0102436
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24591176, KAKENHI-PROJECT-26461200
[Journal Article] Acquired resistance of non-small cell lung cancer to epidermal growth factor receptor tyrosine kinase inhibitors.2014
- Author(s)
  Nurwidya F, Takahashi F, Takahashi K. et al.
- Journal Title
  
  Respir Investig
  
  Volume: 52 Issue: 2 Pages: 82-91
- DOI
  10.1016/j.resinv.2013.07.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591176
[Journal Article] Treatment with insulin-like growth factor 1 receptor inhibitor reverses hypoxia-induced epithelial-mesenchymal transition in non-small cell lung cancer2014
- Author(s)
  Nurwidya F, Takahashi F, Kobayashi I, Murakami A, Kato M, Minakata K, Nara T, Hashimoto M, Yagishita S, Baskoro H, Hidayat M, Shimada N, Takahashi K.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 455 Issue: 3-4 Pages: 332-338
- DOI
  10.1016/j.bbrc.2014.11.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390102, KAKENHI-PROJECT-24591176, KAKENHI-PROJECT-25670205, KAKENHI-PROJECT-26461200
[Journal Article] Hypoxia increases gefitinib-resistant lung cancer stem cells through the activation of insulin-like growth factor 1 receptor2013
- Author(s)
  Murakami A, Takahashi F, Nurwidya F, Kobayashi I, Minakata K, Hashimoto M, Nara T, Kato M, Tajima K, Shimada N, Iwakami S, Moriyama M, Moriyama H, Koizumi F, Takahashi K
- Journal Title
  
  PLoS One
  
  Volume: 9(1) Issue: 1 Pages: e86459-e86459
- DOI
  10.1371/journal.pone.0086459
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23402046, KAKENHI-PROJECT-23591906, KAKENHI-PROJECT-24390102, KAKENHI-PROJECT-24591176, KAKENHI-PROJECT-25670205, KAKENHI-PROJECT-26461200
[Journal Article] Alternative splicing of CD44 mRNA by ESRP1 enhances lung colonization of metastatic cancer cell.2012
- Author(s)
  Yae T, Tsuchihashi K, Ishimoto T, Motohara T, Yoshikawa M, Yoshida GJ, Wada T, Masuko T,Mogushi K, Tanaka H, Osawa T, Kanki Y, et al
- Journal Title
  
  Nature Communications
  
  Volume: 6;3 Issue: 1 Pages: 883-883
- DOI
  10.1038/ncomms1892
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22310117, KAKENHI-PROJECT-23701047, KAKENHI-PROJECT-24221011, KAKENHI-PROJECT-24590389, KAKENHI-PROJECT-24591176, KAKENHI-PROJECT-24591912, KAKENHI-PROJECT-24710227, KAKENHI-ORGANIZER-22130001, KAKENHI-PLANNED-22130007, KAKENHI-PUBLICLY-24116509
[Journal Article] Hypoxia induces gefitinib resistance in non-small-cell lung cancer with both mutant and wild-type epidermal growth factor receptors2012
- Author(s)
  Minakata K, et al. (他12名)
- Journal Title
  
  Cancer Sci
  
  Volume: 103 Issue: 11 Pages: 1946-1954
- DOI
  10.1111/j.1349-7006.2012.02408.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22310158, KAKENHI-PROJECT-23591906, KAKENHI-PROJECT-24390102, KAKENHI-PROJECT-24591176
[Journal Article] Osteopontin-mediated enhanced hyaluronan binding induces multidrug resistance in mesothelioma cells2010
- Author(s)
  Tajima K, Ohashi R, Takahashi K, et al.
- Journal Title
  
  Oncogene
  
  Volume: 29(13) Pages: 1941-51
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591003
[Journal Article] Osteopontin is involved in the development of acquired chemo-resistance of cisplatin in smallcell lung cancer2009
- Author(s)
  Gu T, Takahashi K
- Journal Title
  
  Lung Cancer (in press)
- Data Source
  KAKENHI-PROJECT-19590914
[Journal Article] Osteopontin modulates malignant pleural mesothelioma cell funtions in vitro2009
- Author(s)
  Ohashi R, Takahashi K
- Journal Title
  
  Anticancer Res (in press)
- Data Source
  KAKENHI-PROJECT-19590914
[Journal Article] Osteopontin modulates malignant pleural mesothelioma cell functions in vitro2009
- Author(s)
  Ohashi R, Tajima K, Takahashi K, et al.
- Journal Title
  
  Anticancer Res
  
  Volume: 29(6) Pages: 2205-14
- NAID
  130000122999
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591003
[Journal Article] A novel ELISA system for detection of a "N-ERC/Mesothelin" in the sera of mesothelioma patients.2006
- Author(s)
  Shiomi, K., Miyamoto, H., Segawa, T., Hagiwara, Y., Ota, A., Maeda., M., Takahashi, K., Masuda, K., Sakao, Y., Hino, O.
- Journal Title
  
  Cancer Sci. (in press)
- NAID
  10018767738
- Data Source
  KAKENHI-PROJECT-17800004
[Journal Article] Signal transduction-mediated by endostatin directly modulates cellular function of lung cancer cells in vitro
- Author(s)
  Ri Cui, Kazuhisa Takahashi et al.
- Journal Title
  
  Cancer Science (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590761
[Presentation] Overcoming the drug resistance of fibroblast growth factor receptor -mutated cancer.2023
- Author(s)
  Ikuko Takeda Nakamura, Shinji Kohsaka, Masachika Ikegami, Hiroshi Ikeuchi, Toshihide Ueno, Fumiyuki Takahashi, Kazuhisa Takahashi, Hiroyuki Mano
- Organizer
  日本呼吸器学会
- Data Source
  KAKENHI-PROJECT-21K08187
[Presentation] CALML5 is a novel diagnostic marker for differentiating thymic squamous cell carcinoma from type B3 thymoma.2023
- Author(s)
  Koichiro Kanamori, Kentaro Suina, Takehito Shukuya, Fumiyuki Takahashi, Takuo Hayashi, Kieko Hara, Tsuyoshi Saito, Yoichiro Mitsuishi, Shoko Sonobe Shimamura, Wira Winardi, Ken Tajima, Ryo Ko, Tetsuhiko Asao, Masayoshi Itoh Hideya Kawaji, Yoshiyuki Suehara, Kazuya Takamochi, Kenji Suzuki, Kazuhisa Takahashi.
- Organizer
  日本呼吸器学会
- Data Source
  KAKENHI-PROJECT-21K08187
[Presentation] Development of Hybrid Vision Transformer to Predict Pharmacotherapy Efficacy in Non-Small Cell Lung Cancer Patients2023
- Author(s)
  Shiting Xu, Takehito Shukuya, Kazuhiro Suzuki, Taichi Miyawaki, Shoko Sonobe Shimamura, Hironari Matsuda, Ryota Kanemaru, Tetsuhiko Asao, Tomoyasu Mimori, Yujiro Otsuka, Kazuhisa Takahashi
- Organizer
  第20回日本臨床腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-22K08268
[Presentation] Approaches to Malignant Pleural Mesothelioma by Targeting Epigenetic Modifiers2023
- Author(s)
  Ken Tajima、Yosuke Miyashita、Aditya Wirawan、Kenta Izumi、Naohisa Matsumoto、Yoichiro Mitsuishi、Yasushi Okazaki、Kazuhisa Takahashi
- Organizer
  第82回日本癌学会学術総会 Symposia on Specific Tumors/腫瘍別シンポジウム2
- Data Source
  KAKENHI-PROJECT-23K27465
[Presentation] The role of interleukin-1 alpha in resistance to osimertinib in EGFR mutant non‐small cell lung cancer.2023
- Author(s)
  Wira Winardi, Yoichiro Mitsuishi, Fumiyuki Takahashi, Ken Tajima, Koichiro Kanamori, Aditya Wirawan, Moulid Hidayat, Hironari Matsuda Daisuke Hayakawa, Adityo Wibowo, Kazuhisa Takahashi
- Organizer
  日本呼吸器学会
- Data Source
  KAKENHI-PROJECT-21K08187
[Presentation] 小細胞肺癌における診断・治療標的としてのSKP2の有効性についての研究2023
- Author(s)
  松本直久、田島健、高橋史行、光石陽一郎、宮下洋佑、和泉健太、宿谷威仁、嶋田奈緒子、林大久生、高橋和久
- Organizer
  日本呼吸器学会
- Data Source
  KAKENHI-PROJECT-21K08187
[Presentation] 進行・再発非小細胞肺癌における人工知能を用いた初回癌免疫治療の治療効果予測モデルの構築2023
- Author(s)
  宮脇太一, 宿谷威仁, 鈴木一廣, 中村優介, 大塚裕次朗, 高橋和久
- Organizer
  第64回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-22K08268
[Presentation] Approaches to Malignant Pleural Mesothelioma by Targeting Epigenetic Modifiers2023
- Author(s)
  Ken Tajima、Yosuke Miyashita、Aditya Wirawan、Kenta Izumi、Naohisa Matsumoto、Yoichiro Mitsuishi、Yasushi Okazaki、Kazuhisa Takahashi
- Organizer
  第82回日本癌学会学術総会　Symposia on Specific Tumors/腫瘍別シンポジウム2
- Data Source
  KAKENHI-PROJECT-23K21435
[Presentation] Efficacy and safety of the transbronchial lung cryobiopsy: a single-center retrospective study in Japan.2022
- Author(s)
  T Nishimaki, K Kurokawa, T Miyawaki, T Asao, R Kanemaru, T Mimori, S Kuriyama, Y Mitsuishi, M Ichikawa, N Shimada, T Hayashi, K Takahashi.
- Organizer
  The 26th Congress of the Asian Pacific Society of Respirology(APSR)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08524
[Presentation] 進行・再発性非小細胞肺癌における初回癌免疫治療の臨床的予後予測モデルの構築2022
- Author(s)
  宮脇太一、内藤立暁、高橋史行、高橋利明、髙橋和久
- Organizer
  日本呼吸器学会
- Data Source
  KAKENHI-PROJECT-21K08187
[Presentation] FGFR遺伝子のがん化能および薬剤感受性に対する網羅的機能解析2022
- Author(s)
  中村育子、高阪真路、池上政周、上野敏秀、高橋史行、高橋和久、間野博行
- Organizer
  日本呼吸器学会
- Data Source
  KAKENHI-PROJECT-21K08187
[Presentation] Outcomes associated with immune-related adverse events in non-small cell lung cancer treated with pembrolizumab plus chemotherapy2022
- Author(s)
  K Kurokawa, Y Mitsuishi, N Shimada, K Miura, T Miyawaki, T Asao, R Ko, T Shukuya, R Shibayama, K Takahashi
- Organizer
  第62回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-20K08524
[Presentation] 非小細胞肺癌における抗ミュラー管ホルモン2型受容体（AMHR2）の発現と細胞増殖における役割の検討．2022
- Author(s)
  濃沼淑芳，光石陽一郎，高橋史行，Wira Winardi，金森幸一郎，林大久生，高持一矢，鈴木健司，高橋和久
- Organizer
  第62回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-20K08524
[Presentation] 非小細胞肺癌における抗ミュラー管ホルモン2型受容体 (AMHR2)の発現と細胞増殖における役割の検討2022
- Author(s)
  濃沼淑芳, 光石陽一郎, 高橋史行, Wira Winardi, 金森幸一郎, 林大久生, 高持一矢, 鈴木健司, 髙橋和久
- Organizer
  日本呼吸器学会
- Data Source
  KAKENHI-PROJECT-21K08187
[Presentation] Comprehensive functional evaluation of variants of fibroblast growth factor receptor genes2022
- Author(s)
  中村育子、高阪真路、上野敏秀、高橋史行、高橋和久、間野博行
- Organizer
  日本癌学会
- Data Source
  KAKENHI-PROJECT-21K08187
[Presentation] 免疫チェックポイント阻害剤（ICI）による肺障害を呈した肺癌患者へのステロイド投与に関する後方視的検討．2022
- Author(s)
  大熊智子，三森友靖，宿谷威仁，増田孝一，三浦啓太，黒川加奈，早川乃介，徐仁美，宮脇太一，朝尾哲彦，金丸良太，光石陽一郎，嶋田奈緒子，田島健，高橋和久
- Organizer
  第62回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-20K08524
[Presentation] Efficacy and safety of the transbronchial lung cryobiopsy: a single-center retrospective study in Japan.2022
- Author(s)
  Y Nagata, T Nagaoka, Y Kuroda, S Hotta, T Okuma, K Masuda, N Sakamoto, T Nishimaki, K Kurokawa, T Miyawaki, T Asao , R Kanemaru, T Mimori, S Kuriyama, Y Mitsuishi, M Ichikawa, N Shimada, T Hayashi, K Takahashi.
- Organizer
  The 26th Congress of the Asian Pacific Society of Respirology(APSR)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08524
[Presentation] 胸水中浮遊腫瘍細胞の網羅的遺伝子解析2021
- Author(s)
  中村育子、高阪真路、宿谷威仁、光石陽一郎、高橋史行、高橋和久、間野博行
- Organizer
  第62回日本肺癌学会学術講演会
- Data Source
  KAKENHI-PROJECT-18K08185
[Presentation] Activation of IGF1R receptor confers acquired resistance to osimertinib in EGFR-mutant NSCLC with T790M mutation.2021
- Author(s)
  Daisuke Hayakawa, Fumiyuki Takahashi, Ken Tajima, Yoichiro Mitsuishi, Ikuko Takeda Nakamura, Wira Winardi, Yukina Shirai, Yosuke Miyashita, Tomoko Yamada, Keita Miura, Masahiro Torasawa, Hironari Matsuda, Tetsuhiko Asao, Takehito Shukuya, Kazuhisa Takahashi.
- Organizer
  第80回日本癌学会学術講演会
- Data Source
  KAKENHI-PROJECT-18K08185
[Presentation] Activation of IGF1R receptor confers acquired resistance to osimertinib in EGFR-mutant NSCLC with T790M mutation.2021
- Author(s)
  Daisuke Hayakawa, Fumiyuki Takahashi, Ken Tajima, Yoichiro Mitsuishi, Ikuko Takeda Nakamura, Wira Winardi, Yukina Shirai, Yosuke Miyashita, Tomoko Yamada, Keita Miura, Masahiro Torasawa, Hironari Matsuda, Tetsuhiko Asao, Takehito Shukuya, Kazuhisa Takahashi.
- Organizer
  第80回日本癌学会学術講演会
- Data Source
  KAKENHI-PROJECT-21K08187
[Presentation] Highly sensitive fusion detection using plasma cell-free RNA in non-small-cell lung cancers.2021
- Author(s)
  Nobuhiko Hasegawa, Shinji Kohsaka, Kana Kurokawa, Yuki Shinno, Ikuko Nakamura, Toshihide Ueno, Yoshiyuki Suehara, Muneaki Ishijima, Yasushi Goto, Takuo Hayashi, Tsuyoshi Saito, Takehito Shukuya, Fumiyuki Takahashi, Kazuhisa Takahashi, Hiroyuki Mano.
- Organizer
  第80回日本癌学会学術講演会
- Data Source
  KAKENHI-PROJECT-21K08187
[Presentation] 胸水中浮遊腫瘍細胞の網羅的遺伝子解析2021
- Author(s)
  中村育子、高阪真路、宿谷威仁、光石陽一郎、高橋史行、高橋和久、間野博行．
- Organizer
  第62回日本肺癌学会学術講演会
- Data Source
  KAKENHI-PROJECT-21K08187
[Presentation] Highly sensitive fusion detection using plasma cell-free RNA in non-small-cell lung cancers.2021
- Author(s)
  Nobuhiko Hasegawa, Shinji Kohsaka, Kana Kurokawa, Yuki Shinno, Ikuko Nakamura, Toshihide Ueno, Yoshiyuki Suehara, Muneaki Ishijima, Yasushi Goto, Takuo Hayashi, Tsuyoshi Saito, Takehito Shukuya, Fumiyuki Takahashi, Kazuhisa Takahashi, Hiroyuki Mano.
- Organizer
  第80回日本癌学会学術講演会
- Data Source
  KAKENHI-PROJECT-18K08185
[Presentation] 重複癌の既往と進行非小細胞肺癌に対する1次治療ペムブロリズマブの治療効果との関連の検討2020
- Author(s)
  三浦啓太、宿谷威仁、朝尾哲彦、阿部瞳、白井由紀奈、和泉研太、早川乃介、松本直久、金森幸一郎、嶋村尚子、光石陽一郎、田島健、柴山里奈、嶋田奈緒子、高橋史行、高遼、高橋和久
- Organizer
  第61回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09669
[Presentation] 進行EGFR遺伝子変異/ALK融合遺伝子陽性NSCLCにおける、治療開始後5年以降の経過の検討2020
- Author(s)
  嶋村尚子，宿谷威仁，藤岡雅大，朝尾哲彦，白井由紀奈，三浦啓太, 和泉研太, 早川乃介，高遼，光石陽一郎，田島健，柴山里奈，嶋田奈緒子，髙橋史行，高橋和久
- Organizer
  第61回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09669
[Presentation] 重複癌の既往と進行非小細胞肺癌に対する1次治療ペムブロリズマブの治療効果との関連の検討2020
- Author(s)
  三浦啓太、宿谷威仁、朝尾哲彦、阿部瞳、白井由紀奈、和泉研太、早川乃介、松本直久、金森幸一郎、嶋村尚子、光石陽一郎、田島健、柴山里奈、嶋田奈緒子、高橋史行、高遼、高橋和久
- Organizer
  第61回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08185
[Presentation] インスリン様成長因子1受容体の活性化はT790M遺伝子変異陽性NSCLCにおけるオシメルチニブ耐性に寄与する2020
- Author(s)
  早川乃介、髙橋史行、光石陽一郎、田島健、中村育子、松本直久、金森幸一郎、高遼、朝尾哲彦、宿谷威仁、嶋村尚子、和泉研太、Wira Winardi、白井由紀奈、虎澤匡洋、三浦啓太、藤岡雅大、高橋和久
- Organizer
  第61回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08185
[Presentation] 進行EGFR遺伝子変異/ALK融合遺伝子陽性NSCLCにおける、治療開始後5年以降の経過の検討2020
- Author(s)
  嶋村尚子，宿谷威仁，藤岡雅大，朝尾哲彦，白井由紀奈，三浦啓太, 和泉研太, 早川乃介，高遼，光石陽一郎，田島健，柴山里奈，嶋田奈緒子，髙橋史行，高橋和久
- Organizer
  第61回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08185
[Presentation] インスリン様成長因子1受容体の活性化はT790M遺伝子変異陽性NSCLCにおけるオシメルチニブ耐性に寄与する2020
- Author(s)
  早川乃介、髙橋史行、光石陽一郎、田島健、中村育子、松本直久、金森幸一郎、高遼、朝尾哲彦、宿谷威仁、嶋村尚子、和泉研太、Wira Winardi、白井由紀奈、虎澤匡洋、三浦啓太、藤岡雅大、高橋和久
- Organizer
  第61回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09669
[Presentation] Phase I study of afatinib plus bevacizumab in patients with advanced non-small cell lung cancer harboring EGFR mutations2019
- Author(s)
  Tokito T, Ko R, Imamura C, Shukuya T, Shimada N, Koyama R, Yamada K, Ishii H, Azuma K, Takahashi K.
- Organizer
  World Conference on Lung Cancer (WCLC)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08185
[Presentation] The novel therapeutic strategy targeting the mesenchymal phenotype by suppression of LSD1 in mesothelioma2019
- Author(s)
  Wirawan Aditya, 田島健, Hidayat Moulid, 松本直久, 早川乃介, 金森幸一郎, 和泉研太, 嶋村尚子, 朝尾哲彦, 嶋田奈緒子, 光石陽一郎, 高橋史行, 高橋和久
- Organizer
  日本癌学会総
- Data Source
  KAKENHI-PROJECT-16K09586
[Presentation] SLC7A11 expression confers cancer stem-like properties in small cell lung cancer cells2019
- Author(s)
  Kamenori S, Suina K, Yamasaki J, Shintani S, Otsuki Y, Hirata Y, Okazaki S, Tsuchihashi K, Sampetrean O, Mitsuishi Y, Takahashi F, Takahashi K, Saya H, Nagano O
- Organizer
  American Association of Cancer Research(AACR) Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08185
[Presentation] Clinicopathological characteristics of lung adenocarcinoma with EGFR compound mutations.2019
- Author(s)
  Hayashi T, Kohsaka S, Takamochi K, Takahashi F, Suehara Y, Saito T, Suzuki K, Mano H, Yao T
- Organizer
  United States and Canadian Academy of Pathology (USCAP)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09669
[Presentation] SLC7A11 expression confers cancer stem-like properties in small cell lung cancer cells2019
- Author(s)
  Kamenori S, Suina K, Yamasaki J, Shintani S, Otsuki Y, Hirata Y, Okazaki S, Tsuchihashi K, Sampetrean O, Mitsuishi Y, Takahashi F, Takahashi K, Saya H, Nagano O
- Organizer
  American Association of Cancer Research(AACR) Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09669
[Presentation] Usefulness of elastography strain ratio for the evaluation of benign and malignant lesions during endobronchial ultrasound-guided transbronchial needle aspiration.2019
- Author(s)
  Fujioka M, Takagi H, Motomura H, Hayashi M, Kuwasaki E, Asao T, Ichikawa M, Mitsuishi Y, Shimada N, Nagaoka T, Suzuki T, Takahashi K.
- Organizer
  Asian Pacific Society of Respirology (APSR), International Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08185
[Presentation] Nrf2 expression in surgically resected lung adenocarcinomas: Its association with clinicopathologic features and driver oncogene alterations2019
- Author(s)
  Takamochi K, Hayashi T, Hara K, Mitsuishi Y, Takahashi F, Suehara Y, Suzuki K
- Organizer
  European Society for Medical Oncology (ESMO), International Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09669
[Presentation] Usual interstitial pneumonia pattern in the lower lung lobes as a prognostic factor in idiopathic pleuroparenchymal fibroelastosis.2018
- Author(s)
  Kono K, Kato M, Nakamura T, Yamada T, Tajima M, Ihara H, Tajima K, Shiota S, Takahashi F, Sasaki S, Seyama K, Takahashi K.
- Organizer
  American Thoracic Society 2018 International Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09230
[Presentation] Usual interstitial pneumonia pattern in the lower lung lobes as a prognostic factor in idiopathic pleuroparenchymal fibroelastosis.2018
- Author(s)
  Kono K, Kato M, Nakamura T, Yamada T, Tajima M, Ihara H, Tajima K, Shiota S, Takahashi F, Sasaki S, Seyama K, Takahashi K.
- Organizer
  American Thoracic Society 2018 International Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09669
[Presentation] The role of histone deacetylase in the maintenance of gefitinib-resistant lung cancer stem cells with epidermal growth factor receptor mutation.2018
- Author(s)
  Nurwidya F, Takahashi F, Hidayat M, Wirawan A, Baskoro H, Kato M, Tajima K, Shimada N, Andarini S.L, Yunus F, Takahashi K.
- Organizer
  American Thoracic Society 2018 International Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09230
[Presentation] The role of histone deacetylase in the maintenance of gefitinib-resistant lung cancer stem cells with epidermal growth factor receptor mutation.2018
- Author(s)
  Nurwidya F, Takahashi F, Hidayat M, Wirawan A, Baskoro H, Kato M, Tajima K, Shimada N, Andarini S.L, Yunus F, Takahashi K.
- Organizer
  American Thoracic Society 2018 International Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09669
[Presentation] Pneumothorax in patients with idiopathic interstitial pneumonias.2018
- Author(s)
  Haraguchi M, Kato M, Nakamura T, Horikoshi K, Yoshikawa H, Ihara H, Asao T, Okamoto S, Takagi H, Takahashi F, Sekiya M, Seyama K, Takahashi K.
- Organizer
  American Thoracic Society 2018 International Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08185
[Presentation] In search of new therapy targeting histone methylation in cancer (International Symposium)2018
- Author(s)
  Ken Tajima, Yae Toshifumi, Fumiyuki Takahashi, Shyamala Maheswaran, Kazuhisa Takahashi
- Organizer
  日本呼吸器学会総会
- Data Source
  KAKENHI-PROJECT-16K09586
[Presentation] Pneumothorax in patients with idiopathic interstitial pneumonias.2018
- Author(s)
  Haraguchi M, Kato M, Nakamura T, Horikoshi K, Yoshikawa H, Ihara H, Asao T, Okamoto S, Takagi H, Takahashi F, Sekiya M, Seyama K, Takahashi K.
- Organizer
  American Thoracic Society 2018 International Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09230
[Presentation] Usual interstitial pneumonia pattern in the lower lung lobes as a prognostic factor in idiopathic pleuroparenchymal fibroelastosis.2018
- Author(s)
  Kono K, Kato M, Nakamura T, Yamada T, Tajima M, Ihara H, Tajima K, Shiota S, Takahashi F, Sasaki S, Seyama K, Takahashi K.
- Organizer
  American Thoracic Society 2018 International Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08185
[Presentation] Pneumothorax in patients with idiopathic interstitial pneumonias.2018
- Author(s)
  Haraguchi M, Kato M, Nakamura T, Horikoshi K, Yoshikawa H, Ihara H, Asao T, Okamoto S, Takagi H, Takahashi F, Sekiya M, Seyama K, Takahashi K.
- Organizer
  American Thoracic Society 2018 International Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09669
[Presentation] The role of histone deacetylase in the maintenance of gefitinib-resistant lung cancer stem cells with epidermal growth factor receptor mutation.2018
- Author(s)
  Nurwidya F, Takahashi F, Hidayat M, Wirawan A, Baskoro H, Kato M, Tajima K, Shimada N, Andarini S.L, Yunus F, Takahashi K.
- Organizer
  American Thoracic Society 2018 International Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08185
[Presentation] The Role of LSD1/KDM1 Isoform LSD1+8a in Small Cell Lung Carcinoma2017
- Author(s)
  Ihara H, Takahashi F, Takahashi K, et al.
- Organizer
  Congress of American Thoracic Society (ATS)
- Place of Presentation
  Washington
- Year and Date
  2017-05-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461200
[Presentation] The Epigenetic Roles of LSD1+8a in Small Cell Lung Cancer2017
- Author(s)
  Aditya Wirawan、田島健、高橋史行、Moulid Hidayat、金丸良太、濃沼淑芳、早川乃介、田島学、松本直久、金森幸一郎、武田育子、加藤元康、小林功、嶋田奈緒子、高橋和久
- Organizer
  The International Association for the Study of Lung Cancer
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09586
[Presentation] Role of the ubiquitin ligase FBXW7/CDC4 in the maintenance of quiescent cancer stem cells resistant to gefitinib in EGFR mutation-positive non-small cell lung cancer (NSCLC).2017
- Author(s)
  Hidayat M, Takahashi F, Tajima K, Nurwidya F, Wirawan A, Kanemaru R, Koinuma Y, Ihara H, Tajima M, Matsumoto N, Kanamori K, Takeda I, Haraguchi M, Hayakawa D, Ko R, Kato M, Shibayama R, Koyama R, Takahashi M, Shimada N, Takahashi K.
- Organizer
  World Conference on Lung Cancer of the International Association for the Study of Lung Cancer (IASLC)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09669
[Presentation] Dasatinib Suppresses TGFβ-induced Epithelial Mesenchymal Transition and Inhibits Pulmonary Fibrosis.2017
- Author(s)
  Kanemaru R, Kato M, Takahashi F, et al.
- Organizer
  Congress of American Thoracic Society (ATS)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461200
[Presentation] The Role of LSD1/KDM1 Isoform LSD1+8a in Small Cell Lung Carcinoma2017
- Author(s)
  Ihara H, Takahashi F, Takahashi K, et al.
- Organizer
  Congress of American Thoracic Society (ATS)
- Place of Presentation
  Washington
- Year and Date
  2017-05-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09230
[Presentation] Role of the ubiquitin ligase FBXW7/CDC4 in the maintenance of quiescent cancer stem cells resistant to gefitinib in EGFR mutation-positive non-small cell lung cancer (NSCLC).2017
- Author(s)
  Hidayat M, Takahashi F, Takahashi K, et al.
- Organizer
  World Conference on Lung Cancer of the International Association for the Study of Lung Cancer (IASLC)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09230
[Presentation] Role of quiescent cancer stem cells in the gefitinib resistance in EGFR mutation positive non-small cell lung cancer (NSCLC).2017
- Author(s)
  Hidayat M, Takahashi F, Takahashi K, et al.
- Organizer
  Congress of the Asian Pacific Society of Respirology (APSR)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09230
[Presentation] The Epigenetic Roles of LSD1+8a in Small Cell Lung Cancer.2017
- Author(s)
  Wirawan A, Tajima K, Takahashi F, Hidayat M, Kanemaru R, Koinuma Y, Hayakawa D, Tajima M, Matsumoto N, Kanamori K, Takeda1 I, Kato M, Kobayashi I, Shimada N, Takahashi K.
- Organizer
  World Conference on Lung Cancer of the International Association for the Study of Lung Cancer (IASLC)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09669
[Presentation] Histone deacetylase inhibition alters stem cell phenotype in gefitinib-resistant lung cancer cells with epidermal growth factor receptor mutation.2017
- Author(s)
  Nurwidya F, Takahashi F, Hidayat M, Kobayashi I, Wirawan A, Kato M, Tajima K, Shimada N, Yunus, Takahashi K.
- Organizer
  World Conference on Lung Cancer of the International Association for the Study of Lung Cancer (IASLC)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09669
[Presentation] Bleomycin Induced Epithelial Mesenchymal Transition in Mice.2017
- Author(s)
  Kato M, Takahashi F, et al.
- Organizer
  Congress of American Thoracic Society (ATS)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461200
[Presentation] 小細胞肺がんにおけるヒストン脱メチル化酵素LSD1+8aの役割2016
- Author(s)
  Aditya Wirawan、田島健、丈達陽順、柳下薫寛、高遼、Moulid Hidayat、金丸良太、濃沼淑芳、井原宏彰、嶋田奈緒子、茂櫛薫、高橋史行、高橋和久
- Organizer
  第57回日本肺癌学会総会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2016-12-19
- Data Source
  KAKENHI-PROJECT-16K09586
[Presentation] Knockdown of Oct4 reverses epithelial-mesenchymal transition induced by insulin-like growth factor 1 in lung cancer.2016
- Author(s)
  Nurwidya F, Takahashi F, Takahashi K. et al.
- Organizer
  Asian Pacific Society of Respirology (APSR)
- Place of Presentation
  Bangkok
- Year and Date
  2016-11-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09230
[Presentation] Knockdown of Oct4 reverses epithelial-mesenchymal transition induced by insulin-like growth factor 1 in lung cancer.2016
- Author(s)
  Nurwidya F, Takahashi F, Takahashi K. et al.
- Organizer
  Asian Pacific Society of Respirology (APSR)
- Place of Presentation
  Bangkok
- Year and Date
  2016-11-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461200
[Presentation] Cerebral infarction in advanced non-small cell lung cancer2015
- Author(s)
  Kato M, Takahashi F, Takahashi K, et al.
- Organizer
  Asian Pacific Society of Respirology
- Place of Presentation
  Kuala Lumpur
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PROJECT-24591176
[Presentation] Role of POU5F1 in gefitinib resistance in EGFR-mutant non-small cell lung cancer (NSCLC)2015
- Author(s)
  Kobayashi I, Takahashi F, Takahashi K, et al.
- Organizer
  日本呼吸器学会総会（英語ポスター発表）
- Place of Presentation
  東京
- Year and Date
  2015-04-17
- Data Source
  KAKENHI-PROJECT-26461200
[Presentation] Cerebral infarction in advanced non-small cell lung cancer2015
- Author(s)
  Kato M, Takahashi F, Takahashi K, et al.
- Organizer
  Asian Pacific Society of Respirology
- Place of Presentation
  Kuala Lumpur
- Year and Date
  2015-12-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461200
[Presentation] Role of POU5F1 in gefitinib resistance in EGFR-mutant non-small cell lung cancer (NSCLC)2015
- Author(s)
  Kobayashi I, Takahashi F, Takahashi K, et al.
- Organizer
  日本呼吸器学会総会（英語ポスター発表）
- Place of Presentation
  東京
- Year and Date
  2015-04-17
- Data Source
  KAKENHI-PROJECT-24591176
[Presentation] Role of POU5F1 in gefitinib resistance in EGFR-mutant non-small cell lung cancer (NSCLC)2015
- Author(s)
  Kobayashi I, Takahashi F, Takahashi K, et al.
- Organizer
  日本呼吸器学会総会（英語ポスター発表）
- Place of Presentation
  東京
- Year and Date
  2015-04-17
- Data Source
  KAKENHI-PROJECT-15K09230
[Presentation] Cerebral infarction in advanced non-small cell lung cancer2015
- Author(s)
  Kato M, Takahashi F, Takahashi K, et al.
- Organizer
  Asian Pacific Society of Respirology
- Place of Presentation
  Kuala Lumpur
- Year and Date
  2015-12-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09230
[Presentation] Hypoxia increases gefitinib-resistant lung cancer stem cells through the activation of insulin-like growth factor 1 receptor.2013
- Author(s)
  Murakami A, Takahashi F, Takahashi K. et al.
- Organizer
  Asian Pacific Society of Respirology
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24591176
[Presentation] Knockdown of zinc-finger E-box-binding homeobox 1 (ZEB1) reduces stem cells characteristic of gefitinib-resistant-persisters of PC9 cells.2013
- Author(s)
  Nurwidya F, Takahashi F, Takahashi K. et al.
- Organizer
  Asian Pacific Society of Respirology
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24591176
[Presentation] Role of ZEB1 in hypoxia-induced epithelial mesenchymal transisition and stem cell features in NSCLC. (English poster session).2013
- Author(s)
  Nurwidya F, Takahashi F, Takahashi K. et al.
- Organizer
  日本肺癌学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24591176
[Presentation] ZEB1 is Involved in Hypoxia-induced Gefitinib Resistance in Non-Small Cell Lung Cancer with Sensitive EGFR Mutation (English poster session).2013
- Author(s)
  Nurwidya F, Takahashi F, Takahashi K. et al.
- Organizer
  日本呼吸器学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24591176
[Presentation] ZEB1 is Involved in Hypoxia-induced Gefitinib Resistance in Non-Small Cell Lung Cancer with Sensitive EGFR Mutation2013
- Author(s)
  Fariz Nurwidya, Fumiyuki Takahashi, Akiko Murakami, Isao Kobayashi, Kunihiko Minakata, Yoshito Hoshika, Ryo Ko, Shigehiro Yagishita, Naoko Shimada, Kazuhisa Takahashi
- Organizer
  日本呼吸器学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24591176
[Presentation] 非小細胞肺癌の低酸素誘導性EGFR-TKI耐性機序におけるZEB1の関与2012
- Author(s)
  村上朗子、高橋史行、南方邦彦、Fariz Nurwidya、田島健、加藤元康、村木慶子、宿谷威仁、八戸すず、八戸敏史、大橋里奈、小山良、石渡俊次、平間未知大、森貴紀、高橋元美、瀬山邦明、高橋和久
- Organizer
  日本呼吸器学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24591176
[Presentation] Osteopontin mediated enhanced hyaluronan binding induces multidrug resistance in mesothelioma cells2009
- Author(s)
  Tajima K, Ohashi R, Takahashi K, et al.
- Organizer
  104^<th> American Thoracic Society(ATS)
- Place of Presentation
  San Diego, USA
- Year and Date
  2009-05-19
- Data Source
  KAKENHI-PROJECT-21591003
[Presentation] 胸膜中皮腫におけるオステオポンチンの抗がん剤耐性に対する検討2008
- Author(s)
  田島健(高橋和久)
- Organizer
  第49回日本肺癌学会総会
- Place of Presentation
  小倉
- Year and Date
  2008-11-14
- Data Source
  KAKENHI-PROJECT-19590914
[Presentation] 胸膜中皮腫におけるオステオポンチンの抗がん剤耐性に対する検討2008
- Author(s)
  田島健ら(高橋和久)
- Organizer
  日本肺癌学会学術集会
- Place of Presentation
  小倉 (九州)
- Year and Date
  2008-11-14
- Data Source
  KAKENHI-PROJECT-19590914
[Presentation] Role of osteopontin in malignant pleural mesothelioma cell line2007
- Author(s)
  Ohashi R, Takahashi K, et al.
- Organizer
  102^<th> American Thoracic Society(ATS)
- Place of Presentation
  San Francisco, USA
- Year and Date
  2007-05-23
- Data Source
  KAKENHI-PROJECT-21591003
[Presentation] オステオポンチンは悪性胸膜中皮腫の細胞機能に影響を与える2007
- Author(s)
  大橋里奈(高橋和久)
- Organizer
  第48回日本肺癌学会総会
- Place of Presentation
  名古屋
- Year and Date
  2007-11-09
- Data Source
  KAKENHI-PROJECT-19590914
[Presentation] Expression of osteopontin and CD44 in malignant pleural mesothelioma cell lines(poster session)2006
- Author(s)
  Ohashi R, Takahashi F, Takahashi K, et al.
- Organizer
  11^<th> Congress of the Asian Pacific Society of Respirology(APSR)
- Place of Presentation
  Japan
- Year and Date
  2006-11-21
- Data Source
  KAKENHI-PROJECT-21591003
[Presentation] Epithelial-mesenchymal transition-driven gefitinib resistance in non-small cell lung cancer is mediated by zinc-finger E-box protein 1.
- Author(s)
  Nurwidya F, Takahashi F, Murakami A, Kobayashi I, Kato M, Minakata K, Yagishita S, Koyama R, Muraki K, Takahashi M, Shimada N, Takahashi K.
- Organizer
  Congress of American Thoracic Society (ATS)
- Place of Presentation
  San Diego, USA
- Year and Date
  2014-05-16 – 2014-05-21
- Data Source
  KAKENHI-PROJECT-26461200
[Presentation] Oct4 plays a key role in the persistence of gefitinib-resistant lung cancer stem cells.
- Author(s)
  Kobayashi I, Takahashi F, Nurwidya F, Murakami A, Kato M, Shimada N, Suina K, Kanemaru R, Yagishita S, Ko R, Asao T, Ohashi R, Muraki K, Yoshioka Y, Takahashi M, Takahashi K.
- Organizer
  Congress of the Asian Pacific Society of Respirology (APSR)
- Place of Presentation
  Bali, Indonesia
- Year and Date
  2014-11-13 – 2014-11-16
- Data Source
  KAKENHI-PROJECT-24591176
[Presentation] Oct4 plays a key role in the persistence of gefitinib-resistant lung cancer stem cells.
- Author(s)
  Kobayashi I, Takahashi F, Nurwidya F, Murakami A, Kato M, Shimada N, Suina K, Kanemaru R, Yagishita S, Ko R, Asao T, Ohashi R, Muraki K, Yoshioka Y, Takahashi M, Takahashi K.
- Organizer
  Congress of the Asian Pacific Society of Respirology (APSR)
- Place of Presentation
  Bali, Indonesia
- Year and Date
  2014-11-13 – 2014-11-16
- Data Source
  KAKENHI-PROJECT-26461200
[Presentation] Translational Evidence of Zinc finger E-box binding homeoprotein 1 Involvement in Acquired Resistance to Gefitinib in Non-small Cell Lung Cancer
- Author(s)
  Nurwidya F, Takahashi F, Kobayashi I, Shimada N, Murakami A, Baskoro H, Suina K, Kanemaru R, Yagishita S, Asao T, Ohashi R, Muraki K, Yoshioka Y, Takahashi M, Sasaki S, Takahashi K.
- Organizer
  Congress of the Asian Pacific Society of Respirology (APSR)
- Place of Presentation
  Bali, Indonesia
- Year and Date
  2014-11-13 – 2014-11-16
- Data Source
  KAKENHI-PROJECT-26461200
[Presentation] Epithelial-mesenchymal transition-driven gefitinib resistance in non-small cell lung cancer is mediated by zinc-finger E-box protein 1.
- Author(s)
  Nurwidya F, Takahashi F, Murakami A, Kobayashi I, Kato M, Minakata K, Yagishita S, Koyama R, Muraki K, Takahashi M, Shimada N, Takahashi K.
- Organizer
  Congress of American Thoracic Society (ATS)
- Place of Presentation
  San Diego, USA
- Year and Date
  2014-05-16 – 2014-05-21
- Data Source
  KAKENHI-PROJECT-24591176
[Presentation] Translational Evidence of Zinc finger E-box binding homeoprotein 1 Involvement in Acquired Resistance to Gefitinib in Non-small Cell Lung Cancer
- Author(s)
  Nurwidya F, Takahashi F, Kobayashi I, Shimada N, Murakami A, Baskoro H, Suina K, Kanemaru R, Yagishita S, Asao T, Ohashi R, Muraki K, Yoshioka Y, Takahashi M, Sasaki S, Takahashi K.
- Organizer
  Congress of the Asian Pacific Society of Respirology (APSR)
- Place of Presentation
  Bali, Indonesia
- Year and Date
  2014-11-13 – 2014-11-16
- Data Source
  KAKENHI-PROJECT-24591176

1. TAKAHASHI Fumiyuki (70327823)

# of Collaborated Projects: 13 results

# of Collaborated Products: 90 results
2. Tajima Ken (50384102)

# of Collaborated Projects: 9 results

# of Collaborated Products: 26 results
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TAKAHASHI Kazuhisa 高橋 和久

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中皮腫における細胞系譜構築による新規治療法の探究と臨床応用Principal Investigator

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analysis of novel transcript variant of tyrosine kinase gene in thymic carcinomaPrincipal Investigator

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Role of quiescent cancer stem cells in the gefitinib resistance in EGFR mutation positive non-small cell lung cancerPrincipal Investigator

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TAKAHASHI Kazuhisa 高橋和久