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Imoto MASAYA  井本 正哉

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… Alternative Names

IMOTO Masaya  井本 正哉

井本 正哉  イモト マサヤ

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Researcher Number 60213253
Other IDs
Affiliation (Current) 2018 : 慶應義塾大学, 理工学部(矢上), 教授
Affiliation (based on the past Project Information) *help 2015 – 2018 : 慶應義塾大学, 理工学部(矢上), 教授
2002 – 2018 : 慶應義塾大学, 理工学部, 教授
2013 : 慶應義塾大学, 理工学部(矢上), 教授
1999 – 2001 : 慶應義塾大学, 理工学部, 助教授
1999 – 2000 : 慶応義塾大学, 理工学部, 助教授 … More
1998 : 慶応大学, 理工学部, 助教授
1997 : 慶応義塾大学, 理工学部, 助教授
1996 : 慶應義塾大学, 理工学部, 助教授
1995 : 慶応義塾大学, 理工学部, 助教授
1992 – 1993 : 慶應義塾大学, 理工学部, 講師 Less
Review Section/Research Field
Principal Investigator
Living organism molecular science / Biological Sciences / Chemical biology / Science and Engineering / Bioinformatics/Life informatics / Basic Section 37020:Chemistry and chemical methodology of biomolecules-related / Biomolecular chemistry
Except Principal Investigator
Science and Engineering / Neurology / Biological Sciences … More / Chemical biology / Basic Section 52020:Neurology-related / Chemical biology / Biomedical engineering/Biological material science / 医薬分子機能学 / Biomolecular chemistry / Bioinformatics/Life informatics / Chemical biology / Medium-sized Section 52:General internal medicine and related fields Less
Keywords
Principal Investigator
アポトーシス / 細胞遊走 / オートファジー / ケミカルバイオロジー / がん / パーキンソン疾患 / CysLT1 / 癌 / 5-リポキシゲナーゼ / がん細胞 … More / イノスタマイシン / パーキンソン病 / シグナル伝達 / 前立腺がん / V-ATPase / レプトマイシン / 遺伝子 / 放線菌培養液 / EGF / Bcl-2 / BH1ドメイン / 天然物リガンド / UTKO-1 / 癌悪性化 / α-synuclein / ラメリポディア / ピエリシジン / プロモーター / Bax / アンドロゲン受容体 / Rac / リポキシゲナーゼ / 核外移行シグナル / ムベラスチン / 酵素阻害剤 / Rac1 / EMT / ceramide合成 / 14-3-3 / pRB / プロファイル / PKC / 微生物二次代謝産物 / UTKO1 / セラミド / CDC25A / ゲルフェリン / 2次元電気泳動 / パーキンソン症 / 神経変性疾患 / MPP / 天然化合物 / パスウェイ解析 / 低分子量Gタンパク質 / 脊索管形成 / ビオチン標識 / ゲラニルゲラニル基合成酵素 / プロテオーム / 浸潤 / パーキンソン / アンドロゲンアンタゴニスト / 遊走 / アルゴリズム / ノナクチン / 化学発生学 / ホヤ / フィロポディア / 遺伝的アルゴリズム / 隠れマルコフモデル / EGF受容体 / システム生物学 / 異常増殖 / アンギノマイシンB / 細胞運動 / FGF receptor / PDGF受容体 / キサントフモール / ペプチドマスフィンガープリント / CysLT1アンタゴニスト / ドミナントネガティブ / マイグラスタチン / βカテニン / イノシトールリン脂質代謝回転 / 神経細胞 / ロイコトリエンC_4 / VCP / E2F-1 / HeLa細胞 / アンタルライド / 転移 / がん転移 / 作用解析機構 / サイクリンD1 / コンセンサス配列 / パスウエイ解析 / 難治疾患 … More
Except Principal Investigator
パーキンソン病 / ケミカルバイオロジー / オートファジー / 血管新生 / 転移 / スクリーニング / 血小板産生 / 天然物化学 / 小胞体ストレス / がん遺伝子 / 内科 / がん抑制遺伝子 / 神経変性疾患 / 小分子化合物 / 標的同定 / 制癌物質 / シグナル伝達 / 脳・神経 / リソソーム / 癌抑制遺伝子 / 情報伝達系 / 神経内科学 / cyclin D1 / 管腔形成 / ゲノム・エピゲノム解析支援 / 胆汁輸送 / カドヘリン / 制がん物質 / IL-6 / 天然物 / ミトファジー / 分子細胞生物学 / 足場非依存性増殖 / 阻害剤 / 転写因子結合部位 / PERK / 制がん剤 / 遺伝子改変マウス / ファルネシルトランスフェラーゼ / RB / 細胞外マトリックス / マイクロバイオメカニクス / 国際研究者交流（米国） / プロモーター / クロマチン免疫沈降 / ATL発がん機序 / 生物活性リガンド / モデル動物作製 / 分子プロファイリング / 化学コミュニケーション / 生合成 / 肝細胞 / 臓器円環 / 主成分分析 / hidden Markov model / データベース / 決定木 / 病理形態学 / 転写制御 / 天然物ケミカルバイオロジー / 癌遺伝子 / 分子設計 / 比較解析 / クラスタリング / EMT / 同期的収縮 / 国際研究者交流（中国） / ゲルダナマイシン / 細胞周期 / がん分子標的薬剤 / BiFC / 国際交流（米国） / Ets-1 / promoter sequence / コロニー / ゲルシフトアッセイ / U0126 / 神経変性 / 転写因子 / 異分野融合 / transcriptional regulation / 再生肝臓 / 制がん剤耐性 / タンパク質合成阻害剤 / ATL発症予防 / UPR / 国際研究者交流（韓国） / 国際交流（ドイツ） / 血小板由来増殖因子 / マイトファジー / 活性化酸素 / 小型肝細胞 / 接着 / Srcチロシンキナーゼ / 転写結合モチーフ / 抗がん剤 / がん化シグナル / 次世代分子解析技術 / 天然物リガンド / 収縮運動 / TGF-beta / 毛細胆管 / ミトコンドリア / シスプラチン / 肝臓再生 / レポーターアッセイ / 固形がん悪性 / 国際交流 / アポトーシス / がん化学予防 / IRE1 / ゲノム編集 / 2D-DIEG / 収縮機構 / 細胞間相互作用 / Ras蛋白質 / Hsp-90 / チロシンキナーゼ阻害剤 / 行動解析 / 神経保護作用 / p7056キナーゼ / 骨格筋 / 隠れマルコフモデル / 個別化がん予防 / 人工配位子 / 国際交流（スウェーデン） / 薬剤感受性 / 病理形態解析 / 研究支援 / 細胞接着 / イメージング / man-made chelator / 若手支援 / 上皮間葉転換 / p21^<waf1> / 分子探索・プロファイリング / 複合培養 / Ablチロシンキナーゼ / アカデミア創薬 / プロテオーム解析 / 分子探索・ブロファイリング / XBP1 / 国際交流（韓国） / 分子疫学コーホート研究 / 生理機能解析 / 国際研究者交流 / ATL発症リスク / transcription biding site / 創薬シーズ / 薬剤耐性 / 化合物 / モチーフ変異体 / Ras protein / farnesyltransferase / HSP-90 / ゲノムコーホート研究 / マクロライド / Srcがん遺伝子 / MAPキナーゼ / oncogene / 蛋白分解 / センサータンパク質 / chromatin immunoprecipitation / 分子標的 / バイオインフォマティクス / 固形がん悪性化 / がん転移 / CDKインヒビター / Rasがん遺伝子 / IRE1α / EGFR / ATF6 Less

  • Research Projects

    (32results)

  • Research Products

    (460results)

  • Co-Researchers

    (331People)

  •  Chemical Biology for Parkinson's diseasePrincipal InvestigatorOngoing

    • Principal Investigator
      井本 正哉
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 37020:Chemistry and chemical methodology of biomolecules-related
    • Research Institution
      Keio University

  •  Identification of Parkinson's disease progression markers based on skeletal muscle-brain axisOngoing

    • Principal Investigator
      斉木 臣二
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52020:Neurology-related
    • Research Institution
      Juntendo University

  •  Identification of Parkinson disease-specific mitochondrial pathogenesis for disease-modifying therapyOngoing

    • Principal Investigator
      斉木 臣二
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
    • Review Section
      Medium-sized Section 52:General internal medicine and related fields
    • Research Institution
      Juntendo University

  •  Chemical communications in microbial interactions and development of useful bioactive ligandsOngoing

    • Principal Investigator
      掛谷 秀昭
    • Project Period (FY)
      2017 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Science and Engineering
    • Research Institution
      Kyoto University

  •  先端モデル動物支援プラットフォームOngoing

    • Principal Investigator(Support)
      今井 浩三
    • Project Period (FY)
      2016 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas ― Platforms for Advanced Technologies and Research Resources
    • Research Institution
      The University of Tokyo

  •  Chemical Biological studies for autophagyPrincipal Investigator

    • Principal Investigator
      IMOTO MASAYA
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biomolecular chemistry
    • Research Institution
      Keio University

  •  Development of anti-PD chemicals modulating autophagic activity based on lysosomal function

    • Principal Investigator
      Shinji Saiki
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      Juntendo University

  •  Molecular mechanism of neuroprotective activity of geldanamycin

    • Principal Investigator
      NISHIKAWA Toshio
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Biomolecular chemistry
    • Research Institution
      Nagoya University

  •  Discovery of MET-inducing compounds as anti-cancer chemotherapeutic agents

    • Principal Investigator
      Tashiro Etsu
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Chemical biology
    • Research Institution
      Keio University

  •  Studies on Ciona notochord tubulogenesis by chemical biology approachPrincipal Investigator

    • Principal Investigator
      IMOTO Masaya
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Chemical biology
    • Research Institution
      Keio University

  •  Development of autophagy enhancing chemicals based on Parkinson's disease pathogenesis.

    • Principal Investigator
      SAIKI Shinji
    • Project Period (FY)
      2013 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Juntendo University

  •  Chemical biology using natural products

    • Principal Investigator
      UEDA Minoru
    • Project Period (FY)
      2011 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Science and Engineering
    • Research Institution
      Tohoku University

  •  Discovery of natural products that modulate cellular responsesPrincipal Investigator

    • Principal Investigator
      Imoto Masaya
    • Project Period (FY)
      2011 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Science and Engineering
    • Research Institution
      Keio University

  •  Imaging the activation behavior of ER stress sensors

    • Principal Investigator
      TASHIRO ETSU
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Chemical biology
    • Research Institution
      Keio University

  •  Scientific Support Programs for Cancer Research Grant-in-Aid for Scientific Research on Innovative Areas

    • Principal Investigator
      IMAI Kohzoh, 中村 祐輔
    • Project Period (FY)
      2010 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Research Institution
      The University of Tokyo

  •  Chemical Biology on Cancer and Neurodegenerative diseasePrincipal Investigator

    • Principal Investigator
      IMOTO Masaya
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Living organism molecular science
    • Research Institution
      Keio University

  •  A combination study of chemical and systems biology identifying novelfeatures of signaling pathway in cancer cell migrationPrincipal Investigator

    • Principal Investigator
      IMOTO Masaya
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Living organism molecular science
    • Research Institution
      Keio University

  •  Effects of mitophagy on cell death in Parkinson's disease model cells

    • Principal Investigator
      SAIKI Shinji
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Neurology
    • Research Institution
      Juntendo University

  •  がん悪性化機構を標的とした抗がん剤リード化合物の開発Principal Investigator

    • Principal Investigator
      井本 正哉
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Keio University

  •  Studies on the role of XBP1 in tumor malignancy

    • Principal Investigator
      TASHIRO Etsu
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Chemical biology
    • Research Institution
      Keio University

  •  Studies on regulatory mechanism for cell migration based on chemical geneticsPrincipal Investigator

    • Principal Investigator
      IMOTO Masaya
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Living organism molecular science
    • Research Institution
      Keio University

  •  Development of an information-intensive basis for cancer chemotherapy

    • Principal Investigator
      YAMORI Takao
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Japanese Foundation For Cancer Research

  •  SYS tern Analysis of Transcriptional Regulation Program

    • Principal Investigator
      SAKAKIBARA Yasubumi
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Bioinformatics/Life informatics
    • Research Institution
      KEIO UNIVERSITY

  •  計算的プロテオーム解析による核外移行シグナルの同定Principal Investigator

    • Principal Investigator
      井本 正哉
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Bioinformatics/Life informatics
    • Research Institution
      Keio University

  •  再生毛細胆管の収縮を生み出す小型肝細胞収縮の同期機構のバイオメカニクス

    • Principal Investigator
      谷下 一夫
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      Keio University

  •  がん細胞の悪性化を阻害する物質の探索Principal Investigator

    • Principal Investigator
      井本 正哉
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Keio University

  •  細胞がん化のシグナル伝達の解析と特異的阻害剤の探索

    • Principal Investigator
      上原 至雅
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      National Institute of Infectious Diseases

  •  癌細胞のホメオスタシスを破壊する薬剤の開発と分子機構解析Principal Investigator

    • Principal Investigator
      井本 正哉
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Keio University

  •  Molecular Design of Ras Farnesyltransferase Inhibitors

    • Principal Investigator
      OTSUKA Masami
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      医薬分子機能学
    • Research Institution
      Kumamoto University

  •  がん増悪因子とその制御に作用する制がん物質の研究

    • Principal Investigator
      UEHARA Yoshimasa
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      国立予防衛生研究所

  •  癌増悪因子とその制御に作用する制癌物質の研究

    • Principal Investigator
      石塚 雅章
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Microbial Chemistry Research Foundation

  •  細胞増殖制御因子および耐性因子に作用する制癌剤の探索とその応用

    • Principal Investigator
      石塚 雅章
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Microbial Chemistry Research Foundation

All 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Book

  • [Book] カレントレビュー192015
    • Author(s)
      井本正哉
    • Total Pages
      189
    • Publisher
      化学同人
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Book] 最新がん薬物療法学2015
    • Author(s)
      田代悦，井本正哉
    • Total Pages
      704
    • Publisher
      （株）日本臨床社
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Book] 最新がん薬物療法学2015
    • Author(s)
      北川光洋、田代悦、井本正哉
    • Publisher
      (株)日本臨床社
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Book] 最新がん薬物療法学2014
    • Author(s)
      田代悦，井本正哉
    • Total Pages
      704
    • Publisher
      日本臨床社
    • Data Source
      KAKENHI-PROJECT-26350974

  • [Book] 特集オートファジーに挑むケミカルバイオロジー「天然物化学とケミカルバイオロジーの挑戦」2014
    • Author(s)
      田代悦、井本正哉
    • Publisher
      (株)化学工業社
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Book] オートファジーに挑むケミカルバイオロジー　「天然物化学とケミカルバイオロジーの挑戦」2014
    • Author(s)
      北川光洋，田代悦，井本正哉
    • Total Pages
      79
    • Publisher
      （株）化学工業社
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Book] 特集・制がん剤の分子標的スクリーニング成績 「化学療法基盤情報支援班」報告-制がん候補物質のスクリーニング成績・第14報『癌と化学療法オンライン』2013
    • Author(s)
      矢守隆夫, 上原至雅, 深澤秀輔, 吉田稔, 井本正哉, 清宮啓之, 水上民夫, 川田学, 長田裕之, 松浦正明.
    • Publisher
      癌と化学療法社
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Book] 特集・制がん剤の分子標的スクリーニング成績 「化学療法基盤情報支援班」報告‐制がん候補物質のスクリーニング成績・第15報『癌と化学療法オンライン』2013
    • Author(s)
      矢守隆夫, 上原至雅, 深澤秀輔, 吉田稔, 井本正哉, 清宮啓之, 馬島哲夫, 水上民夫, 川田学, 長田裕之, 旦慎吾, 松浦正明, 掛谷秀昭, 冨田章弘.
    • Publisher
      癌と化学療法社
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Book] 特集・制がん剤の分子標的スクリーニング成績 化学療法基盤情報支援班報告-制がん候補物質のスクリーニング成績・第14報-2013
    • Author(s)
      矢守隆夫, 上原至雅, 深澤秀輔, 吉田稔, 井本正哉, 清宮啓之, 水上民夫, 川田学, 長田裕之, 松浦正明.
    • Publisher
      癌と化学療法社
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Book] 特集・制がん剤の分子標的スクリーニング成績 化学療法基盤支援活動報告-制がん候補物質のスクリーニング成績・第15報2013
    • Author(s)
      矢守隆夫, 上原至雅, 深澤秀輔, 吉田稔, 井本正哉, 清宮啓之, 馬島哲夫, 水上民夫, 川田学, 長田裕之, 旦慎吾, 松浦正明, 掛谷秀昭, 冨田章弘
    • Publisher
      癌と化学療法社
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Book] Ⅱ． 基礎研究 ３． ケミカルバイオロジーと構造生物学 (２) 制がん剤シードの探索（増刊日本臨床 11月号）2012
    • Author(s)
      藤巻貴宏, 井本正哉.
    • Publisher
      日本臨床社
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Book] 特集・制がん剤の分子標的スクリーニング成績「化学療法基盤情報支援班」報告-制がん候補物質のスクリーニング成績・第13報-2010
    • Author(s)
      矢守隆夫、上原至雅、吉田稔、井本正哉、清宮啓之、水上民夫、川田学、長田裕之、松浦正明、深澤秀輔
    • Total Pages
      158
    • Publisher
      癌と化学療法
    • Data Source
      KAKENHI-PROJECT-17012025

  • [Book] 「化学療法基盤情報支援班」報告-制がん候補物質のスクリーニング成績・第13報2010
    • Author(s)
      矢守隆夫、上原至誠、吉田稔、井本正哉、清宮啓之、水上民夫, 他
    • Total Pages
      158
    • Publisher
      癌と化学療法社
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Book] 癌と化学療法(特集・制がん剤の分子標的スクリーニング成績「化学療法基盤情報支援班」報告-制がん候補物質のスクリーニング成績・第13報-, 37)2010
    • Author(s)
      矢守隆夫, 上原至雅, 吉田稔, 井本正哉, 清宮啓之, 水上民夫, 川田学, 長田裕之, 松浦正明, 深澤秀輔
    • Data Source
      KAKENHI-PROJECT-17012025

  • [Book] 実験医学(岡野栄之・岩坪威・佐谷秀行編, ケミカルバイオロジーに基づく創薬研究, 分子標的薬開発の新たなる挑戦)2009
    • Author(s)
      河村達郎, 田代悦, 井本正哉
    • Total Pages
      233
    • Data Source
      KAKENHI-PROJECT-17012025

  • [Book] 特集・制がん剤の分子標的スクリーニング成績 「化学療法基盤情報支援班」報告-制がん候補物質のスクリーニング成績・第12報-.2007
    • Author(s)
      矢守隆夫, 上原至雅, 吉田稔, 井本正哉, 清宮啓之, 水上民夫, 川田学, 長田裕之, 松浦正明.
    • Publisher
      癌と化学療法
    • Data Source
      KAKENHI-PROJECT-17012025

  • [Book] 癌と化学療法(特集・制がん剤の分子標的スクリーニング成績 「化学療法基盤情報支援班」報告-制がん候補物質のスクリーニング成績・第12報-, 34)2007
    • Author(s)
      矢守隆夫, 上原至雅, 吉田稔, 井本正哉, 清宮啓之, 水上民夫, 川田学, 長田裕之, 松浦正明
    • Data Source
      KAKENHI-PROJECT-17012025

  • [Book] 文部科学省科学研究費補助金によるがん研究に係る特定領域研究 II「化学療法基盤情報支援班」報告2007
    • Author(s)
      矢守隆夫, 上原至雅, 吉田稔, 井本正哉, 清宮啓之, 水上民夫, 川田学, 長田裕之, 松浦正明
    • Publisher
      癌と化学療法(印刷中)
    • Data Source
      KAKENHI-PROJECT-17012025

  • [Journal Article] Identification of protein kinase C isozymes involved in the anti-proliferative and pro-apoptotic activities of 10-methyl-aplog-1, a simplified analog of debromoaplysiatoxin, in several cancer cell lines.2018
    • Author(s)
      Hanaki Y, Shikata Y, Kikumori M, Hotta N, Imoto M, Irie K
    • Journal Title

      Biochem Biophys Ros Commun

      Volume : 495 Issue : 1 Pages : 438-445

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Journal Article] Early manifestation of dopressivc-like behavior in transgenic mico that express demcntia with Lcwy bodies-linked mutant beta-synuclein.2018
    • Author(s)
      Fujita M, Hagino Y, Takamatsu Y, Shimizu Y, Takamatsu Y, Ikeda K, Hashimoto M
    • Journal Title

      Neuropsychopharmacology Rep

      Volume : 印刷中

    • DOI
      10.1002/npr2.12009
    • Description
      in press
    • Open Access / Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K15565, KAKENHI-PROJECT-26293347, KAKENHI-PROJECT-17H04324, KAKENHI-PROJECT-16H06276

  • [Journal Article] Identification of protein kinase C isozymes involved in the anti-proliferative and pro-apoptotic activities of 10-Methyl-aplog-1, a simplified analog of debromoaplysiatoxin, in several cancer cell lines2018
    • Author(s)
      Yusuke Hanaki, Yuki Shikata, Masayuki Kikumori, Natsuki Hotta, Masaya Imoto, Kazuhiro Irie
    • Journal Title

      Biochem Biophys Res Commun.

      Volume : 495 Pages : 438-445

    • DOI
      10.1016/j.bbrc.2017.11.052
    • Open Access / Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-17H06405, KAKENHI-PROJECT-15H03116, KAKENHI-PROJECT-16J04817

  • [Journal Article] Curcumin and its demethoxy derivatives possess p300HAT inhibitory activity and suppress hypertrophic response in cardiomyocytes2018
    • Author(s)
      Yoichi Sunagawa, Masafumi Funamoto, Shogo Sono, Kana Shimizu, Satoshi Shimizu, Mai Genpei, Yusuke Miyazaki, Yasufumi Katanasaka, Eriko Morimoto, Morio Ueno, Maki Komiyama, Hideaki Kakeya, Hiromichi Wada, Koji Hasegawa, Tasuya Morimoto
    • Journal Title

      J. Pharmacol. Sci

      Volume : 136 Issue : 4 Pages : 212-217

    • Publisher
      Elsevier BV
    • DOI
      10.1016/j.jphs.2017.12.013
    • PMID
      29602708
    • ISSN
      1347-8613
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-17H06401

  • [Journal Article] CIC-DUX4 induces small round cell sarcomas distinct from Ewing sarcoma.2017
    • Author(s)
      Yoshimoto T, Tanaka M, Homme M, Yamazaki Y, Takazawa Y, Antonescu CR, Nakamura T
    • Journal Title

      Cancer Research

      Volume : 印刷中 Pages : 2927-2937

    • DOI
      10.1158/0008-5472.can-16-3351
    • Acknowledgement Compliant / Int'l Joint Research / Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26250029, KAKENHI-PROJECT-16K07131, KAKENHI-PROJECT-16H02676, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H06297

  • [Journal Article] Curcumin β-D-glucuronide plays an important role to keep high levels of free-form curcumin in the blood.2017
    • Author(s)
      Ozawa, H., Imaizumi, A., Sumi, Y., Hashimoto, T., Kanai, M., Makino, Y., Tsuda, T., Takahashi, N., Kakeya, H.
    • Journal Title

      Biol. Pharm. Bull.

      Volume : 40 Pages : 1515-1524

    • DOI
      10.1248/bpb.b17-00339
    • Open Access / Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K07804, KAKENHI-PLANNED-17H06401

  • [Journal Article] Role of NMDA receptor GluN2D subunit in the antidepressant effects of enantiomers of ketamine2017
    • Author(s)
      Ide S, Ikekubo Y, Mishina M, Hashimoto K, Ikeda K
    • Journal Title

      Journal of Pharmacological Sciences

      Volume : 135(3) Issue : 3 Pages : 138-140

    • DOI
      10.1016/j.jphs.2017.11.001
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K15565, KAKENHI-PROJECT-26293347, KAKENHI-PROJECT-16H04676, KAKENHI-PROJECT-17H04324, KAKENHI-PROJECT-16H06276

  • [Journal Article] Metacycloprodigiosin induced cell death selectively in β-catenin-mutated tumor cells2017
    • Author(s)
      Ikeda H, Shikata Y, Watanapokasin R, Tashiro E, Imoto M
    • Journal Title

      J. Antibiot.

      Volume : 70 Pages : 109-112

    • DOI
      10.1038/ja.2016.75
    • Open Access / Int'l Joint Research / Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26350974, KAKENHI-PROJECT-15H03116, KAKENHI-PROJECT-16H06276

  • [Journal Article] Paclitaxel-induced sensory peripheral neuropathy is associated with an ABCB1 single nucleotide polymorphism and older age in Japanese.2017
    • Author(s)
      Tanabe Y, Shimizu C, Hamada A, Hashimoto K, Ikeda K, Nishizawa D, Hasegawa J, Shimomura A, Ozaki Y, Tamura N, Yamamoto H, Yunokawa M, Yonemori K, Takano T, Kawabata H, Tamura K, Fujiwara Y
    • Journal Title

      Cancer Chemother Pharmacol

      Volume : 79(6) Issue : 6 Pages : 1179-1186

    • DOI
      10.1007/s00280-017-3314-9
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08970, KAKENHI-PROJECT-16K15565, KAKENHI-PROJECT-26293347, KAKENHI-PROJECT-17H04324, KAKENHI-PROJECT-26860360, KAKENHI-PROJECT-16H06276

  • [Journal Article] Activity of tick antimicrobial peptide from Ixodes persulcatus (persulcatusin) against cell membranes of drug-resistant Staphylococcus aureus2017
    • Author(s)
      Ikeda H, Shikata Y, Watanapokasin R, Tashiro E, Imoto M.
    • Journal Title

      J Antibiotics

      Volume : 70 Pages : 109-112

    • Open Access / Acknowledgement Compliant / Int'l Joint Research / Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H03116, KAKENHI-PROJECT-16H05036

  • [Journal Article] Arabilin overcomes resistance to AR-targeted therapy2017
    • Author(s)
      Fujimaki T, Saito S, Imoto M.
    • Journal Title

      J. Antiobiot.

      Volume : 70 Pages : 328-330

    • DOI
      10.1038/ja.2016.162
    • Open Access / Acknowledgement Compliant / Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H03116, KAKENHI-PROJECT-16H06276

  • [Journal Article] High-speed and scalable whole-brain imaging in rodents and primates.2017
    • Author(s)
      Seiriki K, Kasai A, Hashimoto T, Schulze W, Niu M, Yamaguchi S, Nakazawa T, Inoue K, Uezono S, Takada M, Naka Y, Igarashi H, Tanuma M, Waschek JA, Ago Y, Tanaka KF, Hayata-Takano A, Nagayasu K, Shintani N, Hashimoto R, Kunii Y, Hino M, Matsumoto J, Yabe H, Nagai T, Fujita K, Matsuda T, Takuma K, Baba A, Hashimoto H
    • Journal Title

      Nouron

      Volume : 94 Issue : 6 Pages : 1085-1100

    • DOI
      10.1016/j.neuron.2017.05.017
    • Peer Reviewed / Int'l Joint Research / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08269, KAKENHI-PROJECT-16KT0193, KAKENHI-PROJECT-17K19454, KAKENHI-PROJECT-17K19488, KAKENHI-INTERNATIONAL-15K21731, KAKENHI-PROJECT-26293020, KAKENHI-ORGANIZER-15H05871, KAKENHI-PUBLICLY-16H01611, KAKENHI-PUBLICLY-16H01621, KAKENHI-PUBLICLY-17H05565, KAKENHI-PUBLICLY-17H05567, KAKENHI-PUBLICLY-17H06030, KAKENHI-PUBLICLY-17H06062, KAKENHI-PLANNED-25117005, KAKENHI-PROJECT-16H02454, KAKENHI-PROJECT-15H03123, KAKENHI-PROJECT-16H05375, KAKENHI-PROJECT-16K15125, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-16H06297

  • [Journal Article] One-step Transformation of Trichloroacetamide into Isonitrile2017
    • Author(s)
      Adachi, M.; Miyasaka, T.; Hashimoto, H.; Nishikawa, T.
    • Journal Title

      Org. Lett.

      Volume : 19 Pages : 380-383

    • DOI
      10.1021/acs.orglett.6b03583
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K12743, KAKENHI-PROJECT-15K07410

  • [Journal Article] Development of an efficient screening system to identify novel bone metabolism-related genes using the exchangeable gene trap mutagenesis mouse models2017
    • Author(s)
      Syuji Kurogi, Tomohisa Sekimoto, Taro Funamoto, Tomomi Ohta, Shihoko Nakamura, Takuya Nagai, Mai Nakahara, Kumiko Yoshinobu, Kimi Araki, Masatake Araki, Etsuo Chosa
    • Journal Title

      SCIENTIFIC REPORTS

      Volume : 7 Pages : 40692-40692

    • Publisher
      nature
    • DOI
      10.1038/srep40692
    • Language
      English
    • Peer Reviewed / Open Access / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26462304, KAKENHI-PROJECT-15K10485, KAKENHI-PROJECT-26462305, KAKENHI-PROJECT-16K07093, KAKENHI-PROJECT-17K11017, KAKENHI-PROJECT-17K19918, KAKENHI-PROJECT-16H06276

  • [Journal Article] Antarlides F?H, new members of the antarlide family produced by Streptomyces sp. BB472017
    • Author(s)
      3.Saito S, Fujimaki T, Panbangred W, Sawa R, Igarashi Y, Imoto M.
    • Journal Title

      J. Antiobiot.

      Volume : 印刷中 Pages : 595-600

    • DOI
      10.1038/ja.2017.6
    • Open Access / Acknowledgement Compliant / Int'l Joint Research / Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H03116, KAKENHI-PROJECT-16H06276

  • [Journal Article] cohesin in the brain leads to defective synapse development and anxiety-related behavior.2017
    • Author(s)
      Fujita Y, Masuda K, Bando M, Nakato R, Katou Y, Tanaka T, Nakayama M, Takao K, Miyakawa T, Tanaka T, Ago Y, Hashimoto H, Shirahige K, Yamashita T.
    • Journal Title

      J Exp Med.

      Volume : 印刷中 Issue : 5 Pages : 1431-1452

    • DOI
      10.1084/jem.20161517
    • Peer Reviewed / Open Access / Acknowledgement Compliant
    • Data Source
      KAKENHI-PUBLICLY-15H01288, KAKENHI-PUBLICLY-15H01347, KAKENHI-ORGANIZER-15H05970, KAKENHI-PLANNED-15H05976, KAKENHI-PROJECT-15H02369, KAKENHI-PROJECT-16H04718, KAKENHI-PROJECT-26670122, KAKENHI-INTERNATIONAL-15K21761, KAKENHI-PROJECT-16K01946, KAKENHI-PROJECT-26293020, KAKENHI-PUBLICLY-16H01270, KAKENHI-PUBLICLY-17H06051, KAKENHI-PROJECT-17H06178, KAKENHI-PROJECT-16K18364, KAKENHI-PROJECT-16H06276

  • [Journal Article] Gut Microbiota Promotes Obesity-Associated Liver Cancer through PGE2-Mediated Suppression of Antitumor Immunity.2017
    • Author(s)
      Loo TM, Kamachi F, Watanabe Y, Yoshimoto S, Kanda H, Arai Y, Nakajima-Takagi Y, Iwama A, Koga T, Sugimoto Y, Ozawa T, Nakamura M, Kumagai M, Watashi K, Taketo MM, Aoki T, Narumiya S, Oshima M, Arita M, Hara E, Ohtani N
    • Journal Title

      Cancer Discovery

      Volume : 7 Pages : 522-538

    • DOI
      10.1158/2159-8290.cd-16-0932
    • Open Access / Acknowledgement Compliant / Int'l Joint Research / Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-15H05905, KAKENHI-PROJECT-26250028, KAKENHI-PROJECT-14J06998, KAKENHI-PROJECT-15K12709, KAKENHI-PROJECT-15K19032, KAKENHI-PROJECT-26670030, KAKENHI-PROJECT-15K19031, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05898, KAKENHI-PROJECT-17H01531, KAKENHI-PROJECT-15H04648, KAKENHI-PROJECT-17H03990, KAKENHI-PROJECT-16H06276

  • [Journal Article] Mitochondrial uncoupler exerts a synthetic lethal effect against β-catenin mutant tumor cells2017
    • Author(s)
      Shikata Yuki、Kiga Masaki、Futamura Yushi、Aono Harumi、Inoue Hiroyuki、Kawada Manabu、Osada Hiroyuki、Imoto Masaya
    • Journal Title

      Cancer Sci.

      Volume : 108 Pages : 772-784

    • DOI
      10.1111/cas.13172
    • Open Access / Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H03116, KAKENHI-PROJECT-15K06888, KAKENHI-PROJECT-16H06276

  • [Journal Article] Protein kinase A inhibition facilitates the antitumor activity of xanthohumol, a valosin-containing protein inhibitor2017
    • Author(s)
      Y. Shikata Y, T. Yoshimaru, M. Komatsu, H. Katoh, R. Sato, S. Kanagaki, Y. Okazaki, S. Toyokuni, E. Tashiro, S. Ishikawa, T. Katagiri, M. Imoto,
    • Journal Title

      Cancer Science

      Volume : 108 Issue : 4 Pages : 785-794

    • Publisher
      Japanese Cancer Association
    • DOI
      10.1111/cas.13175
    • ISSN
      13497006
    • Year and Date
      2017-01-25
    • Description
      Epub ahead of print
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-24108008, KAKENHI-PROJECT-26350974, KAKENHI-PROJECT-26461948, KAKENHI-PROJECT-15K08398, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H02481, KAKENHI-PROJECT-15H03116

  • [Journal Article] Simple generateon of hairless mice for in vivo imaging2017
    • Author(s)
      Hoshino Y, Mizuno S, Kato K, Mizuno-Iijima S, Tanimoto Y, Ishida M, Kajiwara N, Sakasai T, Miwa Y, Takahashi S, Yagami KI, Sugiyama F
    • Journal Title

      Exp Anim

      Volume : 66 Issue : 4 Pages : 437-445

    • DOI
      10.1538/expanim.17-0049
    • PMID
      28717054
    • ISSN
      1341-1357
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-15H05935, KAKENHI-PROJECT-26221004, KAKENHI-PROJECT-15H04281, KAKENHI-PROJECT-16K14589, KAKENHI-PROJECT-16H06276

  • [Journal Article] The mechanics clarifying counterclockwise rotation in most IVF eggs in mice.2017
    • Author(s)
      Ishimoto K, Ikawa M, Okabe M.
    • Journal Title

      Sci Rep.

      Volume : 7 Pages : 43456-43456

    • Open Access / Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Journal Article] Involvement of the MEK/ERK pathway in EGF-induced E-cadherin down-regulation2016
    • Author(s)
      Tashiro E, Henmi S, Odake H, Ino S, Imoto M
    • Journal Title

      Biochem Biophys Res Commun

      Volume : 477 Pages : 801-806

    • DOI
      10.1016/j.bbrc.2016.06.138
    • Acknowledgement Compliant / Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26350974

  • [Journal Article] Antarlides, A new-type of Androgen Receptor (AR) Antagonist, that overcomes resistance to AR-targeted Therapy.2016
    • Author(s)
      Saito S, Fujimaki T, Panbangred W, Igarashi Y, Imoto M.
    • Journal Title

      Angewandte Chemie Int. Ed

      Volume : 55 Pages : 2718-2732

    • DOI
      10.1002/anie.201510079
    • Acknowledgement Compliant / Int'l Joint Research / Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23102006, KAKENHI-PROJECT-15H03116

  • [Journal Article] Yang CC, Suzuki M, Yamakawa S, Uno S, Ishii A, Yamazaki S, Fukatsu R, Fujisawa R, Sakimura K, Tsurimoto T, Masai H.2016
    • Author(s)
      Yang CC, Suzuki M, Yamakawa S, Uno S, Ishii A, Yamazaki S, Fukatsu R, Fujisawa R, Sakimura K, Tsurimoto T, Masai H.
    • Journal Title

      Nature Communications

      Volume : 7 Pages : 12135-12135

    • DOI
      10.1038/ncomms12135
    • Open Access / Acknowledgement Compliant / Int'l Joint Research / Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H04650, KAKENHI-PROJECT-16H04743, KAKENHI-PROJECT-25440011, KAKENHI-PROJECT-16K07456, KAKENHI-PROJECT-16K14675, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-25000015, KAKENHI-PROJECT-26251004

  • [Journal Article] Ulbactins F and G, Polycyclic Thiazoline Derivatives with Tumor Cell Migration Inhibitory Activity from Brevibacillus sp.2016
    • Author(s)
      Igarashi Y, Asano D, Sawamura M, In Y, Ishida T, Imoto M.
    • Journal Title

      Org Lett.

      Volume : 18 Pages : 1658-1661

    • DOI
      10.1021/acs.orglett.6b00531
    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Journal Article] The jasmonate-responsive GTR1 transporter is required for gibberellin-mediated stamen development in Arabidopsis2016
    • Author(s)
      Checchetto, V., Sgalla, A., Sato, Y., Bergantine, E., Szabo, I. and Uozumi, N.
    • Journal Title

      Nature Communications

      Volume : 57 Pages : 862-877

    • DOI
      10.1038/ncomms7095
    • Open Access / Acknowledgement Compliant / Int'l Joint Research / Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25292055, KAKENHI-ORGANIZER-23102001, KAKENHI-PLANNED-23102012, KAKENHI-PUBLICLY-24102504, KAKENHI-PROJECT-24580135, KAKENHI-PUBLICLY-25119725, KAKENHI-PROJECT-15K18678, KAKENHI-PROJECT-15K18687, KAKENHI-PROJECT-15J02984, KAKENHI-PROJECT-26282207

  • [Journal Article] GNAS(R201H) and Kras(G12D) cooperate to promote murine pancreatic tumorigenesis recapitulating human intraductal papillary mucinous neoplasm.2016
    • Author(s)
      Taki, K., Ohmuraya, M., Tanji, E., Komatsu, H., Hashimoto, D., Semba, K., Araki, K., Kawaguchi, Y., Baba, H. and Furukawa, T.
    • Journal Title

      Oncogene.

      Volume : in press Pages : 2407-2412

    • DOI
      10.1038/onc.2015.294
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-25670653, KAKENHI-PLANNED-26110003, KAKENHI-PUBLICLY-26111516, KAKENHI-PROJECT-25640052

  • [Journal Article] Ionic basis for membrane potential resonance in neurons of the inferior olive.2016
    • Author(s)
      Matsumoto-Makidono, Y., Nakayama, H., Yamasaki, M., Miyazaki, T., Kobayashi, K., Watanabe, M., Kano, M., Sakimura, K., Hashimoto, K.
    • Journal Title

      Cell Rep.

      Volume : 16 Pages : 994-1004

    • DOI
      10.1016/j.celrep.2016.06.053
    • Open Access / Acknowledgement Compliant / Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-16H01615, KAKENHI-PLANNED-25117006, KAKENHI-PLANNED-26112002, KAKENHI-PROJECT-24220007, KAKENHI-PROJECT-16H04650, KAKENHI-PROJECT-26460250, KAKENHI-PROJECT-26460251, KAKENHI-PROJECT-15K18342, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H06280, KAKENHI-PROJECT-25000015

  • [Journal Article] Synthesis of firefly luciferin analogues and evaluation of the luminescent properties.2016
    • Author(s)
      Ioka　S, Saitoh T, Iwano S, Suzuki K, Maki S.A., Miyawaki A, Imoto M, and Nishiyama S.
    • Journal Title

      Chem. Eur. J.

      Volume : 未定

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H03116

  • [Journal Article] Chemistry and biology of the compounds that modulate cell migration2016
    • Author(s)
      Tashiro E, Imoto M.
    • Journal Title

      J Ind Microbiol Biotechnol.

      Volume : 43 Pages : 213-9

    • DOI
      10.1007/s10295-015-1654-1
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26350974

  • [Journal Article] MicroRNA-203 Suppresses Invasion and Epithelial-mesenchymal Transition Induction via Targeting NUAK1 and SNAI2 in Head and Neck Cancer2016
    • Author(s)
      Obayashi, M., Yoshida, M., Tsunematsu, T., Ogawa, I., Sasahira, T., Kuniyasu, H., Imoto, I., Abiko, Y., Xu, D., Fukunaga, S., Tahara, H., Kudo, Y., Nagao, T., Takata, T.
    • Journal Title

      Oncotarget

      Volume : 7 Issue : 7 Pages : 8223-8239

    • Publisher
      Impact Journals, LLC
    • DOI
      10.18632/oncotarget.6972
    • ISSN
      19492553
    • Year and Date
      2016-01-22
    • Language
      English
    • Peer Reviewed / Open Access / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K15740, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-26640091, KAKENHI-PROJECT-26290047, KAKENHI-PROJECT-26293304, KAKENHI-PROJECT-26310106, KAKENHI-PROJECT-16H05164

  • [Journal Article] Screening and target identification of bioactive compounds that modulate cell migration and autophagy2016
    • Author(s)
      Tashiro E and Imoto M
    • Journal Title

      Bioorganic & Medicinal Chemistry

      Volume : 24 Pages : 3283-3290

    • DOI
      10.1016/j.bmc.2016.04.014
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26350974

  • [Journal Article] Association of EPAS1 gene rs4953354 polymorphism with susceptibility to lung adenocarcinoma in female Japanese non-smokers2015
    • Author(s)
      Iwamoto, S., Tanimoto K., Nishio Y., Putra A.C., Fuchita H., Ohe M., Sutani A., Kuraki T., Hiyama K., Murakami I., Eguchi H. and Isobe T.
    • Journal Title

      J Thorac Oncol

      Volume : 9

    • DOI
      10.1097/jto.0000000000000309
    • Year and Date
      2015-03-20
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] The A Allele at rs13419896 of EPAS1 Is Associated with Enhanced Expression and Poor Prognosis for Non-Small Cell Lung Cancer2015
    • Author(s)
      Andika C. Putra, Hidetaka Eguchi, Kian Leong Lee, Yuko Yamane, Ewita Gustine, Takeshi Isobe, Masahiko Nishiyama, Keiko Hiyama, Lorenz Poellinger, Keiji Tanimoto*.
    • Journal Title

      PLoS One

      Volume : 10 Pages : 0134496-0134496

    • DOI
      10.1371/journal.pone.0134496
    • Open Access / Acknowledgement Compliant / Int'l Joint Research / Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K11252, KAKENHI-PROJECT-25461159, KAKENHI-PROJECT-221S0001

  • [Journal Article] Low FOXA1 expression predicts good response to neo-adjuvant chemotherapy resulting in good outcomes for luminal HER2-negative breast cancer cases2015
    • Author(s)
      Horimoto, Y., Arakawa A., Harada-Shoji N., Sonoue H., Yoshida Y., Himuro T., Igari F., Tokuda E., Mamat O., Tanabe M., Hino O. and Saito M.
    • Journal Title

      Br J Cancer

      Volume : 112

    • DOI
      10.1038/bjc.2014.595
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] Mechanism for increased hepatic glycerol synthesis in the citrin/mitochondrial glycerol-3-phosphate dehydrogenase double-knockout mouse: Urine glycerol and glycerol 3-phosphate as potential diagnostic markers of human citrin deficiency.2015
    • Author(s)
      Moriyama M, Fujimoto Y, Rikimaru S,Ushikai M, Kuroda E, Kawabe K, Takano K,Asakawa A, Inui A, Eto K, Kadowaki T, Sinasac DS, Okano Y, Yazaki M, Ikeda SI,Zhang C, Song YZ,Sakamoto O, Kure S, Mitsubuchi H, Endo F, Horiuchi M, Nakamura Y, Yamamura KI, Saheki T.
    • Journal Title

      Biochim Biophys Acta

      Volume : 印刷中 Pages : 1787-1795

    • DOI
      10.1016/j.bbadis.2015.04.023
    • Open Access / Acknowledgement Compliant / Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590892, KAKENHI-PROJECT-15K07768, KAKENHI-PROJECT-15K09595, KAKENHI-PROJECT-26450447, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-15J12259, KAKENHI-PROJECT-25461275, KAKENHI-PROJECT-26850209, KAKENHI-PROJECT-26000012

  • [Journal Article] Urethral toxicity after LDR brachytherapy : experience in Japan2015
    • Author(s)
      Tanaka, N., Asakawa I., Hasegawa M. and Fujimoto K.
    • Journal Title

      Brachytherapy

      Volume : 14

    • DOI
      10.1016/j.brachy.2014.09.009
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] Associations between polymorphisms of interleukin-6 and related cytokine genes and serum liver damage markers : a cross-sectional study in the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study2015
    • Author(s)
      Sugimoto Y, Wakai K, Nakagawa H, Suma S, Sasakabe T, Sakamoto T, Takashima N, Suzuki S, Ogawa S, Ohnaka K, Kuriyama N, Arisawa K, Mikami H, Kubo M, Hosono S, Hamajima N, Tanaka H; J-MICC Study Group.
    • Journal Title

      Gene

      Volume : 557 Pages : 158-162

    • DOI
      10.1016/j.gene.2014.12.025
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26460757, KAKENHI-PROJECT-221S0001

  • [Journal Article] B-RAF mutation and accumulated gene methylation in aberrant crypt foci (ACF), sessile serrated adenoma/polyp (SSA/P) and cancer in SSA/P.2015
    • Author(s)
      Inoue A, Okamoto K, Fujino Y, Nakagawa T, Muguruma N, Sannomiya K, Mitsui Y, Takaoka T, Kitamura S, Miyamoto H, Okahisa T, Fujimori T, Imoto I, Takayama T
    • Journal Title

      Br J Cancer

      Volume : 112 Pages : 403-412

    • DOI
      10.1038/bjc.2014.545
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26293176, KAKENHI-PROJECT-26293304, KAKENHI-PROJECT-221S0001

  • [Journal Article] Region-specific regulation of cell proliferation by FGF receptor signaling during the Wolffian duct development.2015
    • Author(s)
      Mika Okazawa, Aki Murashima, Masayo Harada, Naomi Nakagata, Masafumi Noguchi, Mitsuru Morimoto, Tadashi Kimura, David M. Ornitz, Gen Yamada
    • Journal Title

      Dev Biol.

      Volume : 1;400(1) Pages : 139-147

    • DOI
      10.1016/j.ydbio.2015.01.023
    • Open Access / Acknowledgement Compliant / Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25860771, KAKENHI-PROJECT-15K15403, KAKENHI-PROJECT-15K19013, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-15H04300

  • [Journal Article] Syndecan-1 responsive microRNA-126 and 149 regulate cell proliferation in prostate cancer.2015
    • Author(s)
      Tomomi Fujii, Keiji Shimada, Yoshihiro Tatsumi, Kiyohide Fujimoto, Noboru Konishi
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume : 456 Issue : 1 Pages : 183-189

    • Publisher
      Elsevier
    • DOI
      10.1016/j.bbrc.2014.11.056
    • PMID
      http://www.ncbi.nlm.nih.gov/pubmed/25462564
    • ISSN
      0006291X
    • Language
      English
    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26462424, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-26293079

  • [Journal Article] Apoptosis induction associated with the ER stress response through up-regulation of JNK in HeLa cells by gambogic acid2015
    • Author(s)
      Krajarng A, Imoto M, Tashiro E, Fujimaki T, Shinjo S, Watanapokasin R.
    • Journal Title

      BMC Complement Altern Med.

      Volume : 15 Pages : 26-26

    • DOI
      10.1186/s12906-015-0544-4
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26350974

  • [Journal Article] SMK-17, a MEK1/2-specific inhibitor, selectively induces apoptosis in β-catenin-mutated tumors2015
    • Author(s)
      Kiga M, Nakayama A, Shikata Y, Sasazawa Y, Murakami R, Nakanishi T, Tashiro E, Imoto M.
    • Journal Title

      Scientific Reports

      Volume : 5 Pages : 8155-8155

    • DOI
      10.1038/srep08155
    • Open Access / Acknowledgement Compliant / Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23102006, KAKENHI-PROJECT-26350974, KAKENHI-PROJECT-26750373, KAKENHI-PROJECT-221S0001

  • [Journal Article] Chemical biology of compounds obtained from screening using disease models2015
    • Author(s)
      Tashiro E, Imoto M.
    • Journal Title

      Arch Pharm Res.

      Volume : 38 Pages : 1651-60

    • DOI
      10.1007/s12272-015-0633-4
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26350974

  • [Journal Article] No association between Helicobacter pylori infection and diabetes mellitus among a general Japanese population: a cross-sectional study2015
    • Author(s)
      Tamura T, Morita E, Kawai S, Sasakabe T, Sugimoto Y, Fukuda N, Suma S, Nakagawa H, Okada R, Hishida A, Naito M, Hamajima N, Wakai K
    • Journal Title

      Springerplus

      Volume : 4 Pages : 602-602

    • DOI
      10.1186/s40064-015-1371-2
    • Open Access / Acknowledgement Compliant / Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] Reducing DNA methylation suppresses colon carcinogenesis by inducing tumor cell differentiation.2015
    • Author(s)
      Hatano Y, Semi K, Hashimoto K, Lee MS, Hirata A, Tomita H, Kuno T, Takamatsu M, Aoki K, Taketo MM, Kim YJ, Hara A, Yamada Y.
    • Journal Title

      Carcinogenesis.

      Volume : 36 Pages : 719-29

    • DOI
      10.1093/carcin/bgv060
    • Acknowledgement Compliant / Int'l Joint Research / Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-15H04721, KAKENHI-PROJECT-26830069, KAKENHI-PROJECT-24680091

  • [Journal Article] Murine Herc6 plays a critical role in protein ISGylation in vivo and has an ISGylation independent function in seminal vesicles.2015
    • Author(s)
      Arimoto, K., Hishiki, T., Kiyonari, H., Abe, T., Cheng, C., Yan, M., Fan, J. B., Futakuchi, M., Tsuda, H., Murakami, Y., Suzuki, H., Zhang, D. E., and Shimotohno, K.
    • Journal Title

      J Interferon Cytokine Res

      Volume : 35 Pages : 351-358

    • DOI
      10.1089/jir.2014.0113
    • Acknowledgement Compliant / Int'l Joint Research / Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K06837, KAKENHI-PROJECT-15K19109, KAKENHI-PROJECT-221S0001, KAKENHI-PLANNED-22114004, KAKENHI-PROJECT-24501319

  • [Journal Article] Everyday clinical practice in IgG4-related dacryoadenitis and/or sialadentist: Result from the SMART database.2015
    • Author(s)
      Yamamoto M, Yajima H, Takahashi H, Yokoyama Y, Ishigami K, Shimizu Y, Tabeya T, Suzuki C, Naishiro Y, Takano K, Yamashita K, Hashimoto M, Keira Y, Honda S, Abe T, Suzuki Y, Mukai M, Himi T, Hasegawa T, Imai K, Shinomura Y
    • Journal Title

      Modern Rheumatology

      Volume : 25 Pages : 199-204

    • DOI
      10.3109/14397595.2014.950036
    • Int'l Joint Research / Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K10818, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-26640101, KAKENHI-PROJECT-25861575

  • [Journal Article] Evaluation of drug toxicity profiles based on the phenotypes of ascidian Ciona intestinalis.2015
    • Author(s)
      Mizotani Y, Itoh S, Hotta K, Tashiro E, Oka K, Imoto M.
    • Journal Title

      Biochem Biophys Res Commun

      Volume : 463 Pages : 656-60

    • DOI
      10.1016/j.bbrc.2015.05.119
    • Int'l Joint Research / Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26350974, KAKENHI-PLANNED-23102006, KAKENHI-PROJECT-15H03116

  • [Journal Article] Apoptosis induction associated with the ER stress response through up-regulation of JNK in HeLa cells by gambogic acid2015
    • Author(s)
      Krajamg A, Imoto M, Tashiro E, Fujimaki T, Shinjo S, and Watanapokasin R
    • Journal Title

      BMC Complementary & Alternative Medicine

      Volume : 15 Pages : 26-26

    • Open Access / Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26350974

  • [Journal Article] Integrated analysis of whole genome and transcriptome sequencing reveals diverse transcriptomic aberrations driven by somatic genomic changes in liver cancers2015
    • Author(s)
      Shiraishi Y, Fujimoto A, et al.
    • Journal Title

      PLoS ONE

      Volume : 9

    • DOI
      10.1371/journal.pone.0114263
    • Open Access / Acknowledgement Compliant / Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26430196, KAKENHI-PLANNED-22134008, KAKENHI-PUBLICLY-25134717, KAKENHI-PROJECT-25670375, KAKENHI-PROJECT-26670383, KAKENHI-PROJECT-221S0001

  • [Journal Article] 5-lipoxygenase and cysteinyl leukotriene receptor 1 regulate epidermal growth factor-induced cell migration through Tiam1 upregulation and Rac1 activation2014
    • Author(s)
      Magi S, Takemoto Y, Kobayashi H, Kasamatsu M, Akita T, Tanaka A, Takano K, Tashiro E, Igarashi Y, Imoto M.
    • Journal Title

      Cancer Science.

      Volume : 105 Pages : 290-296

    • DOI
      10.1111/cas.12340
    • Open Access / Acknowledgement Compliant / Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23102006, KAKENHI-PROJECT-25560419, KAKENHI-PROJECT-26350974, KAKENHI-PROJECT-221S0001

  • [Journal Article] Nadir PSA level and time to nadir PSA are prognostic factors in patients with metastatic prostate cancer2014
    • Author(s)
      Tomioka, A., Tanaka N., Yoshikawa M., Miyake M., Anai S., Chihara Y., Okajima E., Hirayama A., Hirao Y. and Fujimoto K.
    • Journal Title

      BMC Urol

      Volume : 14

    • DOI
      10.1186/1471-2490-14-33
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] Proteomic Analysis of Proteins Related to Prognosis of Lung Adenocarcinoma.2014
    • Author(s)
      Okayama A, Miyagi Y, Oshita F, Nishi M, Nakamura Y, Nagashima Y, Akimoto K, Ryo A, Hirano H.
    • Journal Title

      J Proteome Res

      Volume : 13 Issue : 11 Pages : 4686-464

    • DOI
      10.1021/pr4012969
    • Open Access / Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26460456, KAKENHI-PROJECT-221S0001

  • [Journal Article] Multicenter phase Ⅱ study of mogamulizumab (KW-0761), a defucosylated anti-cc chemokine receptor 4 antibody, in patients with relapsed peripheral T-cell lymphoma and cutaneous T-cell lymphoma.2014
    • Author(s)
      Ogura M, Ishida T, Hatake K, Taniwaki M, Ando K, Tobinai K, Fujimoto K, Yamamoto K, Miyamoto T, Uike N, Tanimoto M, Tsukasaki K, Ishizawa K, Suzumiya J, Inagaki H, Tamura K, Akinaga S, Tomonaga M, Ueda R.
    • Journal Title

      J Clin Oncol.

      Volume : 32 Pages : 1157-1163

    • DOI
      10.1200/jco.2013.52.0924
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390254, KAKENHI-PROJECT-23501318, KAKENHI-PROJECT-24590677, KAKENHI-PROJECT-221S0001

  • [Journal Article] Photodynamic diagnosis of shed prostate cancer cells in voided urine treated with 5-aminolevulinic acid.2014
    • Author(s)
      Nakai Y, Anai S, Kuwada M, Miyake M, Chihara Y, Tanaka N, Hirayama A, Yoshida K, Hirao Y, Fujimoto K.
    • Journal Title

      BMC Urol.

      Volume : 14 Pages : 14:59

    • Publisher
      BioMed Central
    • DOI
      10.1186/1471-2490-14-59
    • PMID
      http://www.ncbi.nlm.nih.gov/pubmed/25086448
    • ISSN
      14712490
    • Year and Date
      2014-08-03
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25861445, KAKENHI-PROJECT-221S0001

  • [Journal Article] Rat strain differences in levels and effects of chronic inflammation due to intratracheal instillation of quartz on lung tumorigenesis induced by DHPN2014
    • Author(s)
      Nakano Y, Yokohira M, Hashimoto N, Yamakawa K, Kishi S, Ninomiya F, Kanie S, Saoo K, Imaida K
    • Journal Title

      Exp. Toxicol. Pathol

      Volume : 66

    • DOI
      10.1016/j.etp.2014.06.002
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] Disruption of actin-binding domain-containing dystonin protein causes dystonia musculorum in mice.2014
    • Author(s)
      Horie, M., Watanabe, K., Bepari, A. K., Nashimoto, J., Araki, K., Sano, H., Chiken, S., Nambu, A., Ono, K., Ikenaka, K., Kakita, A., Yamamura, K. and Takebayashi, H.
    • Journal Title

      European Journal of Neuroscience

      Volume : 40 Pages : 3458-3471

    • DOI
      10.1111/ejn.12711
    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-23310135, KAKENHI-PROJECT-23590237, KAKENHI-PROJECT-24700351, KAKENHI-PLANNED-25117007, KAKENHI-PROJECT-25351002, KAKENHI-PROJECT-26430021, KAKENHI-PROJECT-221S0001

  • [Journal Article] Xanthohumol suppresses oestrogen-signalling in breast cancer through the inhibition of BIG3-PHB2 interactions2014
    • Author(s)
      T. Yoshimaru, M. Komatsu, E. Tashiro, M. Imoto, H. Osada, Y. Miyoshi, J. Honda, M. Sasa, T. Katagiri
    • Journal Title

      Scientific reports

      Volume : 4 Pages : 7355-7355

    • Acknowledgement Compliant / Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-23102001

  • [Journal Article] Use of alpha-1 adrenoceptor antagonists in patients who underwent low-dose-rate brachytherapy for prostate cancer-a randomized controlled trial of silodosin versus naftopidil2014
    • Author(s)
      Tanaka, N., Torimoto K., Asakawa I., Miyake M., Anai S., Hirayama A., Hasegawa M., Konishi N. and Fujimoto K.
    • Journal Title

      Radiat Oncol

      Volume : 9

    • DOI
      10.1186/s13014-014-0302-7
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] Generation and analysis of serine protease inhibitor Kazal type 3-cre driver mice2014
    • Author(s)
      Sakata, K., Ohmuraya, M., Araki, K., Suzuki, C., Ida, S., Hashimoto, D., Wang, J., Uchiyama, Y., Baba, H. and Yamamura, K.
    • Journal Title

      Exp. Anim.

      Volume : 63

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] Proposed salvage treatment strategy for biochemical failure after radical prostatectomy in patients with prostate cancer : a retrospective study2014
    • Author(s)
      Miyake, M., Tanaka N., Asakawa I., Morizawa Y., Anai S., Torimoto K., Aoki K., Yoneda T., Hasegawa M., Konishi N. and Fujimoto K.
    • Journal Title

      Radiat Oncol

      Volume : 9

    • DOI
      10.1186/1748-717x-9-208
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] Chemical genomic-based pathway analyses for epidermal growth factor-mediated signaling in migrating cancer cell2014
    • Author(s)
      Magi S, Saeki Y, Kasamatsu M, Tashiro E, Imoto M.
    • Journal Title

      PLoS One

      Volume : 9

    • DOI
      10.1371/journal.pone.0096776
    • Open Access / Acknowledgement Compliant / Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23102006, KAKENHI-PROJECT-26350974

  • [Journal Article] Identification of licopyranocoumarin and glycyrurol from herbal medicines as neuroprotective compounds for Parkinson’s disease2014
    • Author(s)
      Fujimaki T, Saiki S, Tashiro E, Yamada D, Kitagawa M, Hattori N and Imoto M.
    • Journal Title

      PLoS One

      Volume : 9

    • DOI
      10.1371/journal.pone.0100395
    • Open Access / Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23102006, KAKENHI-PROJECT-26350974

  • [Journal Article] Hepatoid giant cell tumor of tendon sheath-A rare morphologic variant case report2014
    • Author(s)
      Yoshimoto, T., Motoi, N., Kanda, H., Tanizawa, T., Shimoji, T., Matsumoto, S., Mukai, H., Ishikawa, Y., Machinami, R.
    • Journal Title

      Pathology Res. Practice

      Volume : 14

    • DOI
      10.1016/j.prp.2014.05.012
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] The biochemical recurrence-free rate in patients who underwent prostate low-dose-rate brachytherapy, using two different definitions.2014
    • Author(s)
      Tanaka N, Asakawa I, Katayama E, Hirayama A, Hasegawa M, Konishi N, Fujimoto K
    • Journal Title

      Radiation Oncology

      Volume : 9(1) Pages : 107-107

    • DOI
      10.1186/1748-717x-9-107
    • Open Access / Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390304, KAKENHI-PROJECT-26293079, KAKENHI-PROJECT-221S0001

  • [Journal Article] Xanthohumol suppresses oestrogen-signalling in breast cancer through the specific inhibition of BIG3-PHB2 interactions.2014
    • Author(s)
      Yoshimaru T, Komatsu M, Tashiro E, Imoto M, Osada H, Miyoshi M, Honda J, Sasa M, and Katagiri T
    • Journal Title

      Scientific Reports

      Volume : 4 Pages : 7335-7335

    • DOI
      10.1038/srep07355
    • Open Access / Acknowledgement Compliant / Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23102006, KAKENHI-PUBLICLY-25134712, KAKENHI-PROJECT-25293079, KAKENHI-PROJECT-26350974, KAKENHI-PROJECT-26461948, KAKENHI-PROJECT-26860212, KAKENHI-PROJECT-221S0001

  • [Journal Article] Lung adenocarcinoma subtypes definable by lung development-related miRNA expression profiles in association with clinicopathologic features.2014
    • Author(s)
      Arima C, Kajino T, Tamada Y, Imoto S, ShimadaY, Nakatochi, M, Suzuki M, Isomura H, Yatabe Y, Yamaguchi T, Yanagisawa K, Miyano S, Takahashi T
    • Journal Title

      Carcinogenesis

      Volume : 35 Pages : 2224-2231

    • DOI
      10.1093/carcin/bgu127
    • Acknowledgement Compliant / Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134005, KAKENHI-PROJECT-25293191, KAKENHI-PROJECT-25640076, KAKENHI-PROJECT-26290051, KAKENHI-PROJECT-26670625, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-25250017

  • [Journal Article] 5-Lipoxygenase and CysLT1 regulate EGF-induced cell migration through Tiam1 upregulation and Rac1 activation2014
    • Author(s)
      Magi S, Takemoto Y, Kobayashi H, Kasamatsu M, Akita T, Tanaka A, Takano K, Tashiro E, Igarashi Y, Imoto M
    • Journal Title

      Cancer Science

      Volume : 105 Pages : 290-296

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Journal Article] Novel isoflavone glucosides in Groundnut (Apios americana Medik) and their antiandrogenic activities2013
    • Author(s)
      Ichige M, Fukuda E, Miida S, Hattan J, Misawa N, Saito S, Fujimaki T, Imoto M. Shindo K
    • Journal Title

      J. Agric. Food Chem

      Volume : 61 Pages : 2183-2187

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Journal Article] A Comparative Analysis of the Expression Patterns of UPR-Target Genes caused by UPR-inducing Compounds.2013
    • Author(s)
      Shinjo S, Mizotani Y, Tashiro E, Imoto M.
    • Journal Title

      Biosci. Biotechnol. Biochem.

      Volume : 77 Pages : 729-735

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Journal Article] HCV NS3 protease enhances liver fibrosis via binding to and activating TGF-β type I receptor2013
    • Author(s)
      Sakata K, Eda S, Lee E, Hara M, Imoto M, Kojima S.
    • Journal Title

      Sci. Rep

      Volume : 3 Pages : 3243-3243

    • DOI
      10.1038/srep03243
    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23102006, KAKENHI-PROJECT-23390202, KAKENHI-PLANNED-24115003, KAKENHI-PROJECT-24390111, KAKENHI-PROJECT-25560419, KAKENHI-PROJECT-221S0001

  • [Journal Article] NoNovel derivatives of aclacinomycin A block cancer cell migration through inhibition of farnesyl transferase.2013
    • Author(s)
      Magi S, Shitara T, Takemoto Y, Sawada M, Kitagawa M, Tashiro E. Takahashi Y, Imoto M
    • Journal Title

      J. Antibiot.

      Volume : 66 Pages : 165-170

    • DOI
      10.1038/ja.2012.108
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140, KAKENHI-PROJECT-22651084, KAKENHI-PLANNED-23102006, KAKENHI-PROJECT-25560419, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-10J04895

  • [Journal Article] Early-onset diffuse gastric cancer associated with a de novo large genomic deletion of CDH1 gene.2013
    • Author(s)
      Sugimoto S, Yamada H, Takahashi M, Sugimura H et al.
    • Journal Title

      Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association

      Volume : -

    • DOI
      10.1007/s10120-013-0278-2
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] A Comparative Analysis of the Expression Patterns of UPR-Target Genes caused by UPR-inducing Compounds2013
    • Author(s)
      Shinjo S, Mizotani Y, Tashiro E, Imoto M
    • Journal Title

      Biosci. Biotechnol. Biochem.

      Volume : 77 Pages : 729-735

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Journal Article] Novel derivatives of aclacinomycin A block cancer cell migration through inhibition of farnesyl transferase2013
    • Author(s)
      Magi S, Shitara T, Takemoto Y, Sawada M, Kitagawa M, Tashiro E. Takahashi Y, Imoto M
    • Journal Title

      J. Antibiot.

      Volume : 66 Pages : 165-170

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Journal Article] Novel isoflavone glucosides in Groundnut (Apios americana Medik) and their antiandrogenic activities2013
    • Author(s)
      Ichige M, Fukuda E,Miida S, Hattan J, Misawa N, Saito S, Fujimaki T, Imoto M. Shindo K
    • Journal Title

      J. Agric. Food Chem

      Volume : 61 Pages : 2183-2187

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] A Comparative Analysis of the Expression Patterns of UPR-Target Genes caused by UPR-inducing Compounds2013
    • Author(s)
      Shinjo S, Mizotani Y,Tashiro E, Imoto M
    • Journal Title

      Biosci. Biotechnol. Biochem

      Volume : 77 Pages : 729-735

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome.2013
    • Author(s)
      Yoshimoto, S.
    • Journal Title

      Nature

      Volume : 499 Pages : 97-101

    • DOI
      10.1038/nature12347
    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23112101, KAKENHI-PROJECT-23300343, KAKENHI-PROJECT-23300352, KAKENHI-PROJECT-24650625, KAKENHI-PROJECT-25293080, KAKENHI-PROJECT-221S0001

  • [Journal Article] Establishment of a new detection system for the dimerization of IRE1α with BiFC method.2013
    • Author(s)
      Shinjo S, Tashiro E, Imoto M.
    • Journal Title

      Biosci. Biotechnol. Biochem

      Volume : 77 Pages : 1333-1336

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25560419

  • [Journal Article] Establishment of a new detection system for the dimerization of IRE1α with BiFC method2013
    • Author(s)
      Shinjo S, Tashiro E, Imoto M
    • Journal Title

      Biosci. Biotechnol. Biochem.

      Volume : 77 Pages : 1333-1336

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Journal Article] Investigations of motility and fertilization potential in thawed cryopreserved mouse sperm from cold-stored epididymides.2013
    • Author(s)
      Takeo, T., Fukumoto, K., Kondo, T., Haruguchi, Y., Takeshita, Y., Nakamuta, Y., Tsuchiyama, S., Yoshimoto, H., Shimizu, N., Li, MW., Kinchen, K., Vallelunga, J., Lloyd, KC. and Nakagata, N.
    • Journal Title

      Cryobiology.

      Volume : 68(1) Pages : 12-7

    • DOI
      10.1016/j.cryobiol.2013.10.007
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] Comparative Analysis of the UPR-Target Genes Expression Patterns induced by UPR-Inducing Compounds2013
    • Author(s)
      S. Shinjo, Y. Mizotani, E. Tashiro, and M. Imoto
    • Journal Title

      Biosci. Biotechnol. Biochem.

      Volume : 77

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Journal Article] Lewis y antigen is expressed in oral squamous cell carcinoma cell lines and tissues, but disappears in the invasive regions leading to the enhanced malignant properties irrespective of sialyl-Lewis x.2013
    • Author(s)
      Hotta H., Hamamura K., Yamashita K,. Shibuya H., Tokuda N., Hashimoto N., Furukawa K., Yamamoto N., Hattori H., Toyokuni S., Ueda M., Furukawa K.
    • Journal Title

      Glycoconj J

      Volume : 30 Pages : 585-597

    • DOI
      10.1007/s10719-012-9458-2
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] Establishment of a new detection system for the dimerization of IRE1α using a BiFC assay2013
    • Author(s)
      S. Shinjo, E. Tashiro, and M. Imoto
    • Journal Title

      Biosci. Biotechnol. Biochem.

      Volume : 77

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Journal Article] A Comparative Analysis of the Expression Patterns of UPR-Target Genes caused by UPR-inducing Compounds.2013
    • Author(s)
      Shinjo S, Mizotani Y, Tashiro E, Imoto M.
    • Journal Title

      Biosci. Biotechnol. Biochem

      Volume : 77 Pages : 729-735

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25560419

  • [Journal Article] A Comparative Analysis of the Expression Patterns of UPR-Target Genes caused by UPR-inducing Compounds2013
    • Author(s)
      Shinjo S, Mizotani Y,Tashiro E, Imoto M
    • Journal Title

      Biosci. Biotechnol. Biochem

      Volume : 77 Pages : 729-735

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Journal Article] Establishment of a new detection system for the dimerization of IRE1α with BiFC method.2013
    • Author(s)
      Shinjo S, Tashiro E, Imoto M.
    • Journal Title

      Biosci. Biotechnol. Biochem.

      Volume : 77 Pages : 1333-1336

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Journal Article] Xanthohumol Impairs Autophagosome Maturation through Direct Inhibition of Valosin-Containing Protein2012
    • Author(s)
      Sasazawa Y, Kanagaki S, Tashiro E,Nogawa T, Muroi M, Kondoh Y, Osada H, Imoto M
    • Journal Title

      ACS Chemical Biology

      Volume : 7 Pages : 892-900

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Journal Article] Synthesis and Assignment of the Absolute Configuration of an Indenotryptoline Bisindole Alkaloid2012
    • Author(s)
      Kimura.T, Kanagaki S, Matsui Y, Imoto M, Watanabe T, Shibasaki M
    • Journal Title

      BE-54017. Org. Lett

      Volume : 14 Pages : 4418-4421

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Target identification of bioactive compounds2012
    • Author(s)
      Tashiro E and Imoto M
    • Journal Title

      Bioorg. & Med. Chem.

      Volume : 20 Pages : 1910-1921

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Journal Article] Establishment of a transport system for mouse epididymal sperm at refrigerated temperatures.C2012
    • Author(s)
      Takeo,T., Tsutsumi,A., Omaru,T., Fukumoto,K., Haruguchi,Y., Kondo,T., Nakamuta,Y., Takeshita,Y., Matsunaga,H., Tsuchiyama,S., Sakoh,K., Nakao,S., Yoshimoto,H., Shimizu,N., and Nakagata,N.
    • Journal Title

      Cryobiology.

      Volume : 65 Pages : 163-168

    • DOI
      10.1016/j.cryobiol.2012.06.002
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] Inostamycin enhanced TRAIL-induced apoptosis through DR5 up-regulation on the cell surface2012
    • Author(s)
      Yamamoto K, Makino M, Watanapokasin R, Tashiro Eand Imoto M
    • Journal Title

      J. Antibiot.

      Volume : 65 Pages : 295-300

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Xanthohumol Impairs Autophagosome Maturation through Direct Inhibition of Valosin-Containing Protein2012
    • Author(s)
      Y.Sasazawa, S.Kanagaki, E.Tashiro, T.Nogawa, M.Muroi, Y.Kondoh, H.Osada, M.Imoto
    • Journal Title

      ACS Chemical Biology

      Volume : (in press)(掲載決定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Journal Article] Identification of Toyocamycin, an agent cytotoxic for multiple myeloma cells, as a potent inhibitor of ER stress-induced XBP1 mRNA splicing2012
    • Author(s)
      Ri M, Tashiro E, Oikawa D, Shinjo S, Tokuda M, Yokouchi Y, Narita T, Masaki A, Ito A, Ding J, Kusumoto S, Ishida T, Komatsu H, Shiotsu Y, Ueda R, Iwawaki T, Imoto M, Iida S
    • Journal Title

      Blood Cancer J.

      Volume : e79

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Journal Article] Target identification of bioactive compounds2012
    • Author(s)
      Tashiro Eand Imoto M.
    • Journal Title

      Bioorg. & Med. Chem

      Volume : 20 Pages : 1910-1921

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Comprehensive Predictions of Target Proteins Based on Protein-Chemical Interaction Using Virtual Screening and Experimental Verifications2012
    • Author(s)
      Kobayashi H, et al Imoto M and Sakakibara Y.
    • Journal Title

      BMC Chem. Biol

      Volume : 12 Pages : 2-2

    • DOI
      10.1186/1472-6769-12-2
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140, KAKENHI-PROJECT-23310145

  • [Journal Article] AMF-26, a Novel Inhibitor of the Golgi System, Targeting ADP-ribosylation Factor 1 (Arf1) with Potential for Cancer Therapy.2012
    • Author(s)
      Ohashi Y, Iijima H, Yamaotsu N, Yamazaki K, Sato S, Okamura M, Sugimoto K, Dan S, Hirono S, Yamori T
    • Journal Title

      J Biol Chem.

      Volume : 287(6) Pages : 3885-3897

    • DOI
      10.1074/jbc.m111.316125
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22240092, KAKENHI-PROJECT-22590042, KAKENHI-PROJECT-22700929, KAKENHI-PROJECT-221S0001

  • [Journal Article] 1) Inostamycin enhanced TRAIL-induced apoptosis through DR5 up-regulation on the cell surface2012
    • Author(s)
      K. Yamamoto, M. Makino, R. Watanapokasin, E. Tashiro, and M. Imoto
    • Journal Title

      J. Antibiot.

      Volume : 65 Pages : 295-300

    • DOI
      10.1038/ja.2012.21
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23510283, KAKENHI-PLANNED-23102006

  • [Journal Article] A chemical genomic study identifying diversity in cell migration signaling in cancer cells2012
    • Author(s)
      Magi S, Tashiro E and Imoto M
    • Journal Title

      Scientific Reports

      Volume : 2 Pages : 823-823

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Journal Article] Antitumor effects of novel highly hydrophilic and non-ATP-competitive MEK1/2 inhibitor2012
    • Author(s)
      Kiga M, Tanzawa F, Iwasaki S, Inaba F, Fujiwara K, IwadareH, Echigo T, Nakamura Y, Shibata T, Suzuki K, Yasumatsu, I Nakayama A, Sasazawa Y, Tashiro E, Imoto M, S. Kurakata S
    • Journal Title

      SMK-17. Anticancer Drugs.

      Volume : 23 Pages : 119-130

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Non-invasive X-ray micro-computed tomographic evaluation of indomethacin on urethane- induced lung carcinogenesis in mice.2012
    • Author(s)
      Ueno T, Imaida K, Yoshimoto M, Hayakawa T, Takahashi M, Imai T, Yanaka A, Tsuta K, Komiya M, Wakabayashi K and Mutoh M.
    • Journal Title

      Anticancer Res

      Volume : 32(11) Pages : 4773-80

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] Antitumor effects of novel highly hydrophilic and non-ATP-competitive MEK1/2 inhibitor, SMK-172012
    • Author(s)
      Kiga M, Tanzawa F, Iwasaki S, Inaba F, Fujiwara K, Iwadare H, Echigo T, Nakamura Y, Shibata T, Suzuki K, Yasumatsu, I Nakayama A, Sasazawa Y, Tashiro E, Imoto M, S. Kurakata S
    • Journal Title

      Anticancer Drugs

      Volume : 23 Pages : 119-130

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Journal Article] Inostamycin enhanced TRAIL-induced apoptosis through DR5 up-regulation on the cell surface2012
    • Author(s)
      Yamamoto K, Makino M, Watanapokasin R, Tashiro E and Imoto M
    • Journal Title

      J. Antibiot.

      Volume : 65 Pages : 295-300

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Journal Article] Xanthohumol Impairs Autophagosome Maturation through Direct Inhibition of Valosin-Containing Protein2012
    • Author(s)
      Sasazawa Y, Kanagaki S, Tashiro E,Nogawa T, Muroi M, Kondoh Y, Osada H, Imoto M
    • Journal Title

      ACS Chemical Biology

      Volume : 7 Pages : 892-900

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Toxicity of nicotine by repeated intratracheal instillation to F344 rats.2012
    • Author(s)
      Yokohira M, Nakano Y, Hashimoto N, Yamakawa K, Ninomiya F, Kishi S, Saoo K, Imaida K.
    • Journal Title

      J Toxicol Pathol

      Volume : 25 Pages : 257-263

    • DOI
      10.1293/tox.25.257
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] Xanthohumol Impairs Autophagosome Maturation through Direct Inhibition of Valosin-Containing Protein2012
    • Author(s)
      Y.Sasazawa, S.Kanagaki, E.Tashiro, T.Nogawa, M.Muroi, Y.Kondoh, H.Osada, M.Imoto
    • Journal Title

      ACS Chemical Biology

      Volume : (in press)(掲載決定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Napyradiomycin A1, an inhibitor of mitochondrial complexes I and II2012
    • Author(s)
      Yamamoto K, Tashiro E, Motohashi K, Seto H and Imoto M.
    • Journal Title

      J. Antibiot

      Volume : 65 Pages : 211-214

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Synthesis and Assignment of the Absolute Configuration of an Indenotryptoline Bisindole Alkaloid2012
    • Author(s)
      Kimura.T, Kanagaki S, Matsui Y, Imoto M, Watanabe T, Shibasaki M.
    • Journal Title

      Org. Lett

      Volume : 14 Pages : 4418-4421

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Journal Article] Napyradiomycin A1, an inhibitor of mitochondrial complexes I and II2012
    • Author(s)
      Yamamoto K, Tashiro E, Motohashi K, Seto H and Imoto M
    • Journal Title

      J. Antibiot

      Volume : 65 Pages : 211-214

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Journal Article] A chemical genomic study identifyingdiversity in cell migration signaling in cancer cells2012
    • Author(s)
      Magi S, Tashiro Eand Imoto M
    • Journal Title

      Scientific Reports

      Volume : 2 Pages : 823-823

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Journal Article] Comprehensive Predictions of Target Proteins Based on Protein-Chemical Interaction Using Virtual Screening and Experimental Verifications2012
    • Author(s)
      Kobayashi H, Harada, H, Nakamura M, FutamuraY, Ito A, Yoshida M, Iemura S, Shin-ya K, Doi T, Takahashi T, Natsume T, Imoto Mand Sakakibara Y
    • Journal Title

      BMC Chemical Biology

      Volume : 12 Pages : 2-2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Identification of Toyocamycin, an agent cytotoxic for multiple myeloma cells, as a potent inhibitor of ER stress-induced XBP1 mRNA splicing.2012
    • Author(s)
      Ri M, Tashiro E, Oikawa D, Shinjo S, Tokuda M, Yokouchi Y, Narita T, Masaki A, Ito A, Ding J, Kusumoto S, Ishida T, Komatsu H, Shiotsu Y, Ueda R, Iwawaki T, Imoto M, Iida S
    • Journal Title

      Blood Cancer J.

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Journal Article] A chemical genomic study identifyingdiversity in cell migration signaling in cancer cells.2012
    • Author(s)
      Magi S, Tashiro Eand Imoto M.
    • Journal Title

      Scientific Reports

      Volume : 2 Pages : 823-823

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Prevalence of Bordetella hinzii in mice in experimental facilities in Japan.2012
    • Author(s)
      Hayashimoto, N., Morita, H., Yasuda, M., Ishida, T., Kameda, S., Takakura, A., Itoh, T.
    • Journal Title

      Res.Vet.Sci.

      Volume : 93(2) Pages : 624-6

    • DOI
      10.1016/j.rvsc.2011.11.001
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] 2) Napyradiomycin A1, an inhibitor of mitochondrial complex I and II2012
    • Author(s)
      K. Yamamoto, E. Tashiro, K. Motohashi, H. Seto, and M. Imoto
    • Journal Title

      The Journal of Antibiotics

      Volume : 65 Pages : 211-214

    • DOI
      10.1038/ja.2011.138
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Journal Article] Inostamycin enhanced TRAIL-induced apoptosis through DR5 up-regulation on the cell surface2012
    • Author(s)
      Yamamoto K, Makino M, Watanapokasin R, Tashiro Eand Imoto M
    • Journal Title

      J. Antibiot.

      Volume : 65 Pages : 295-300

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Journal Article] Antitumor effects of novel highly hydrophilic and non-ATP-competitive MEK1/2 inhibitor, SMK-172012
    • Author(s)
      Kiga M, Tanzawa F, Iwasaki S, Inaba F, Fujiwara K, Iwadare H, Echigo T, Nakamura Y, Shibata T, Suzuki K, Yasumatsu, I Nakayama A, Sasazawa Y, Tashiro E, Imoto M , S. Kurakata S
    • Journal Title

      Anticancer Drugs

      Volume : 23 Pages : 119-130

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Journal Article] Comprehensive Predictions of Target Proteins Based on Protein-Chemical Interaction Using Virtual Screening and Experimental Verifications2012
    • Author(s)
      Kobayashi H, Harada, H, Nakamura M, Futamura Y, Ito A, Yoshida M, Iemura S, Shin-ya K, Doi T, Takahashi T, Natsume T, Imoto Mand Sakakibara Y
    • Journal Title

      BMC Chemical Biology

      Volume : 12 Pages : 2-2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Journal Article] Xanthohumol Impairs Autophagosome Maturation through Direct Inhibition of Valosin-Containing Protein2012
    • Author(s)
      Sasazawa Y, Kanagaki S, Tashiro E, Nogawa T, Muroi M, Kondoh Y, Osada H, Imoto M
    • Journal Title

      ACS Chemical Biology

      Volume : 7 Pages : 892-900

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Journal Article] Xanthohumol Impairs Autophagosome Maturation through Direct Inhibition of Valosin-Containing Protein.2012
    • Author(s)
      Sasazawa, Y., Kanagaki, S., Tashiro, E., Nogawa, T., Muroi, M., Kondoh, Y., Osada, H. & Imoto, M
    • Journal Title

      ACS Chem. Biol.

      Volume : 18 Pages : 892-900

    • DOI
      10.1021/cb200492h
    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20113008, KAKENHI-PROJECT-22310140, KAKENHI-PROJECT-23510287, KAKENHI-PLANNED-23102006, KAKENHI-PROJECT-11J03075

  • [Journal Article] Napyradiomycin A1, an inhibitor of mitochondrial complexes I and II2012
    • Author(s)
      Yamamoto K, Tashiro E, Motohashi K, Seto H and Imoto M
    • Journal Title

      J. Antibiot.

      Volume : 65 Pages : 211-214

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Journal Article] A chemical genomic study identifying diversity in cell migration sig2012
    • Author(s)
      Magi S, Tashiro E and Imoto M.
    • Journal Title

      Sci Rep

      Volume : 2 Pages : 823-823

    • DOI
      10.1038/srep00823
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140, KAKENHI-PROJECT-22651084, KAKENHI-PLANNED-23102006

  • [Journal Article] Identification of Toyocamycin, an agent cytotoxic for multiple myeloma cells2012
    • Author(s)
      Ri M, Tashiro E, Oikawa D, Shinjo S, Tokuda M, Yokouchi Y, Narita T, Masaki A, Ito A, Ding J, Kusumoto S, Ishida T, Komatsu H, Shiotsu Y, Ueda R, Iwawaki T, Imoto M, Iida S
    • Journal Title

      as a potent inhibitor of ER stress-induced XBP1 mRNA splicing. Blood Cancer J.e

      Volume : 79

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Target identification of bioactive compounds2012
    • Author(s)
      Tashiro Eand Imoto M
    • Journal Title

      Bioorg. & Med. Chem.

      Volume : 20 Pages : 1910-1921

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Journal Article] A New Convenient Cell-based Screening Method for Small Molecule Glycolytic Inhibitors2011
    • Author(s)
      Kitagawa M, Misawa M, Ogawa S, Tashiro E and Imoto M
    • Journal Title

      Biosci. Biotechnol. Biochem

      Volume : 75 Pages : 367-369

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Journal Article] A new, convenient cell-based screening method for small-molecule glycolytic inhibitors2011
    • Author(s)
      M.Kitagawa, M.Misawa, S.Ogawa, E.Tashiro, M.Imoto
    • Journal Title

      Biosci Biotechnol Biochem 75

      Pages : 367-369

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Journal Article] Mycotrienin II, a translation inhibitor that prevents ICAM-1 expression induced by pro-inflammatory cytokines2011
    • Author(s)
      Yamada Y, Tashiro ETaketani S, Imoto Mand Kataoka T
    • Journal Title

      J. Antibiot

      Volume : 64 Pages : 361-366

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Journal Article] Generation of "Unnatural Natural Product" library and identification of a small molecule inhibitor of XIAP2011
    • Author(s)
      Kawamura T, Matsubara K, Otaka H, Tashiro E, Shindo, K, Yanagita R. C., Irie K and Imoto M
    • Journal Title

      Bioorg. & Med. Chem.

      Volume : 19 Pages : 4377-4385

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Journal Article] Synthesis and anti-migrative evaluation of moverastin derivatives2011
    • Author(s)
      M.Sawada, S.Kubo, K.Matsumura, Y.Takemoto, H.Kobayashi, E.Tashiro, T.Kitahara, H.Watanabe, M.Imoto
    • Journal Title

      Bioorg Med Chem Lett 21

      Pages : 1385-1389

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Journal Article] Mycotrienin II, a translation inhibitor that prevents ICAM-1 expression induced by pro-inflammatory cytokines2011
    • Author(s)
      Yamada Y, Tashiro E, Taketani S, Imoto M and Kataoka T
    • Journal Title

      J. Antibiot.

      Volume : 64 Pages : 361-366

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Journal Article] Caffeine induces apoptosis by enhancement of autophagy via PI3K/Akt/mTOR/p70S6K inhibition.2011
    • Author(s)
      Saiki S, Sasazawa Y, Imamichi Y, Kawajiri S, Fujimaki T, Tanida I, Kobayashi H, Sato F, Kei-Ichi Ishikawa, Sato S, Imoto M, Hattori N.
    • Journal Title

      Autophagy

      Volume : 7 Pages : 176-187

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790853

  • [Journal Article] Oncological outcomes of the prostate cancer patients registered in 2004 : report from the Cancer Registration Committee of the JUA2011
    • Author(s)
      Fujimoto H, et al
    • Journal Title

      Int J Urol

      Volume : 18 Pages : 876-881

    • DOI
      10.1111/j.1442-2042.2011.02895.x
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] Mycotrienin II, a translation inhibitor that prevents ICAM-1 expression induced by pro-inflammatory cytokines2011
    • Author(s)
      Yamada Y, Tashiro ETaketani S, Imoto Mand Kataoka T
    • Journal Title

      J. Antibiot

      Volume : 64 Pages : 361-366

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Generation of "Unnatural Natural Product" library and identification of a small molecule inhibitor of XIAP2011
    • Author(s)
      T.Kawamura, K.Matsubara, H.Otaka, E.Tashiro, K.Shindo, R.C.Yanagita, K.Irie, M.Imoto
    • Journal Title

      Bioorg.& Med.Chem.

      Volume : 19 Pages : 4377-4385

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Synthesis and anti-migrative evaluation of moverastin derivatives2011
    • Author(s)
      Sawada M, Kubo, S Matsumura, K Takemoto Y, Kobayashi H, Tashiro E,Kitahara T, Watanabe H and Imoto M
    • Journal Title

      Bioorg.c & Med. Chem. Lett

      Volume : 21 Pages : 1385-1389

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Journal Article] Quinotrierixin inhibited ER stress-induced XBP1 mRNA splicing through inhibition of protein synthesis2011
    • Author(s)
      K.Yamamoto, E.Tashiro, M.Imoto
    • Journal Title

      Biosci Biotechnol Biochem 75

      Pages : 284-288

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Journal Article] Quinotrierixin Inhibits ER Stress-induced XBP1 mRNA Splicing through Inhibition of Protein Synthesis.2011
    • Author(s)
      K.Yamamoto, E.Tashiro, M.Imoto.
    • Journal Title

      Biosci.Biotechnol.Biochem.

      Volume : (In press 掲載決定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] A new, convenient cell-based screening method for small-molecule glycolytic inhibitors2011
    • Author(s)
      M.Kitagawa, M.Misawa, S.Ogawa, E.Tashiro, M.Imoto
    • Journal Title

      Biosci Biotechnol Biochem

      Volume : 75 Pages : 367-369

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Journal Article] Generation of "Unnatural Natural Product" library and identification of a small molecule inhibitor of XIAP2011
    • Author(s)
      Kawamura T, Matsubara K, Otaka H, Tashiro E, Shindo, K, Yanagita R. C., Irie K and Imoto M
    • Journal Title

      Bioorg. & Med. Chem

      Volume : 19 Pages : 4377-4385

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Journal Article] Involvement of 14-3-3 proteins in the second EGF-induced wave of Rac1 activation in the process of cell migration2011
    • Author(s)
      Kobayashi H, Ogura, Y, Sawada M, Nakayama T, Takano K, Minato Y, Takemoto Y, Tashiro E, Watanabe H & Imoto M
    • Journal Title

      J. Biol. Chem.

      Volume : 286 Pages : 39259-39268

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Journal Article] Caffeine induces apoptosis by enhancement of autophagy via PI3K/Akt/mTOR/p70S6K inhibition2011
    • Author(s)
      Saiki S, Sasazawa Y, Imamichi Y, Kawajiri S, Fujimaki T, Tanida I, Kobayashi H, Sato F, Kei-Ichi Ishikawa, Sato S, Imoto M, Hattori N
    • Journal Title

      Autophagy

      Volume : 7 Pages : 42-53

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Journal Article] Involvement of 14-3-3 proteins in the second epidermal growth factor-induced wave of Rac1 activation in the process of cell migration2011
    • Author(s)
      Hiroki Kobayashi, Yusuke Ogura, Masato Sawada, Ryoji Nakayama, Kei Takano, Yusuke Minato, Yasushi Takemoto, Etsu Tashiro, Hidenori Watanabe, Masaya Imoto
    • Journal Title

      J.Biol.Chem.

      Volume : 286 Pages : 39259-39268

    • DOI
      10.1074/jbc.m111.255489
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J03194, KAKENHI-ORGANIZER-23102001, KAKENHI-PLANNED-23102010

  • [Journal Article] A New Convenient Cell-based Screening Method for Small Molecule Glycolytic Inhibitors2011
    • Author(s)
      Kitagawa M, Misawa M, Ogawa S, Tashiro E and Imoto M
    • Journal Title

      Biosci. Biotechnol. Biochem.

      Volume : 75 Pages : 367-369

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Journal Article] Synthesis and anti-migrative evaluation of moverastin derivatives2011
    • Author(s)
      M.Sawada, S.Kubo, K.Matsumura, Y.Takemoto, H.Kobayashi, E.Tashiro, T.Kitahara, H.Watanabe, M.Imoto
    • Journal Title

      Bioorg.c & Med.l Chen.Lett.

      Volume : 21 Pages : 1385-1389

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Involvement of 14-3-3 proteins in the second EGF-induced wave of Rac1 activation in the process of cell migration2011
    • Author(s)
      H.Kobayashi, Y.Ogura, M.Sawada, R.Nakayama, K.Takano, Y.Minato, Y.Takemoto, E.Tashiro, H.Watanabe, M.Imoto
    • Journal Title

      J.Biol.Chem.

      Volume : 286 Pages : 39259-39268

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Caffeine induces apoptosis by enhancement of autophagy via PI3K/Akt/mTOR/p70S6K inhibition.2011
    • Author(s)
      Saiki S, Sasazawa Y, Imamichi Y, Kawajiri S, Fujimaki T, Tanida I, Kobayashi H, Sato F, Kei-Ichi Ishikawa, Sato S, Imoto M, Hattori N.
    • Journal Title

      Autophagy 7

      Pages : 176-87

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790853

  • [Journal Article] A New Convenient Cell-based Screening Method for Small Molecule Glycolytic Inhibitors.2011
    • Author(s)
      Kitagawa M, Misawa M, Ogawa S, Tashiro E and Imoto M
    • Journal Title

      Biosci. Biotechnol. Biochem

      Volume : 75 Pages : 367-369

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Synthesis and anti-migrative evaluation of moverastin derivatives.2011
    • Author(s)
      M.Sawada, S.Kubo, K.Matsumura, Y.Takemoto, H.Kobayashi, E.Tashiro, T.Kitahara, H.Watanabe, M.Imoto.
    • Journal Title

      Bioorganic & Medicinal Chemistry Letters

      Volume : (In press 掲載決定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Involvement of 14-3-3 proteins in the second EGF-induced wave of Rac1 activation in the process of cell migration2011
    • Author(s)
      H.Kobayashi, Y.Ogura, M.Sawada, R.Nakayama, K.Takano, Y.Minato, Y.Takemoto, E.Tashiro, H.Watanabe, M.Imoto
    • Journal Title

      J.Biol.Chem.

      Volume : 286 Pages : 39259-39268

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Journal Article] Caffeine induces apoptosis by enhancement of autophagy via PI3K/Akt/mTOR/p70S6K inhibition2011
    • Author(s)
      Saiki S, Sasazawa Y, Imamichi Y, Kawajiri S, Fujimaki T, Tanida I, Kobayashi H, Sato F, Kei-Ichi Ishikawa, Sato S, Imoto M, Hattori N
    • Journal Title

      Autophagy

      Volume : 7 Pages : 42-53

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Generation of "Unnatural Natural Product" library and identification of a small molecule inhibitor of XIAP2011
    • Author(s)
      T.Kawamura, K.Matsubara, H.Otaka, E.Tashiro, K.Shindo, R.C.Yanagita, K.Irie, M.Imoto
    • Journal Title

      Bioorg.& Med.Chem.

      Volume : 19 Pages : 4377-4386

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Journal Article] Involvement of 14-3-3 proteins in the second EGF-induced wave of Rac1 activation in the process of cell migration2011
    • Author(s)
      H.Kobayashi, Y.Ogura, M.Sawada, R.Nakayama, K.Takano, Y.Minato, Y.Takemoto, E.Tashiro, H.Watanabe, M.Imoto
    • Journal Title

      J.Biol.Chem.

      Volume : 286 Pages : 39259-39268

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Journal Article] Synthesis and anti-migrative evaluation of moverastin derivatives2011
    • Author(s)
      Sawada M, Kubo, S Matsumura, K Takemoto Y, Kobayashi H, Tashiro E, Kitahara T, Watanabe H and Imoto M
    • Journal Title

      Bioorg.c & Med. Chem. Lett.

      Volume : 21 Pages : 1385-1389

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Journal Article] Quinotrierixin Inhibits ER Stress-induced XBP1 mRNA Splicing through Inhibition of Protein Synthesis2011
    • Author(s)
      Yamamoto K, Tashiro E and Imoto M
    • Journal Title

      Biosci. Biotechnol. Biochem.

      Volume : 75 Pages : 284-288

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Journal Article] Generation of "Unnatural Natural Product" library and identification of a small molecule inhibitor of XIAP2011
    • Author(s)
      Kawamura T, Matsubara K, Otaka H, Tashiro E, Shindo, K, Yanagita R. C., Irie K and Imoto M
    • Journal Title

      Bioorg. & Med. Chem

      Volume : 19 Pages : 4377-4385

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Synthesis and anti-migrative evaluation of moverastin derivatives2011
    • Author(s)
      M.Sawada, S.Kubo, K.Matsumura, Y.Takemoto, H.Kobayashi, E.Tashiro, T.Kitahara, H.Watanabe, M.Imoto
    • Journal Title

      Bioorg Med Chem Lett

      Volume : 21 Pages : 1385-1389

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Journal Article] Synthesis and anti-migrative evaluation of moverastin derivatives2011
    • Author(s)
      M.Sawada, S.Kubo, K.Matsumura, Y.Takemoto, H.Kobayashi, E.Tashiro, T.Kitahara, H.Watanabe, M.Imoto
    • Journal Title

      Bioorg.c & Med.l Chem.Lett.

      Volume : 21 Pages : 1385-1389

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Journal Article] Involvement of 14-3-3 proteins in the second EGF-induced wave of Rac1 activation in the process of cell migration2011
    • Author(s)
      Kobayashi1 H, Ogura, Y, Sawada M, Nakayama T, Takano K, Minato Y, Takemoto Y, Tashiro E, Watanabe H & Imoto M.
    • Journal Title

      J. Biol. Chem

      Volume : 286 Pages : 39259-39268

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Synthesis and anti-migrative evaluation of moverastin derivatives.2011
    • Author(s)
      Sawada M, Kubo, S Matsumura, K Takemoto Y, Kobayashi H, Tashiro E, Kitahara T, Watanabe H and Imoto M
    • Journal Title

      Bioorg.c & Med. Chem. Lett

      Volume : 21 Pages : 1385-1389

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Quinotrierixin Inhibits ER Stress-induced XBP1 mRNA Splicing through Inhibition of Protein Synthesis2011
    • Author(s)
      Yamamoto K, Tashiro Eand Imoto M
    • Journal Title

      Biosci. Biotechnol. Biochem.

      Volume : 75 Pages : 284-288

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Quinotrierixin inhibited ER stress-induced XBP1 mRNA splicing through inhibition of protein synthesis2011
    • Author(s)
      K.Yamamoto, E.Tashiro, M.Imoto
    • Journal Title

      Biosci Biotechnol Biochem

      Volume : 75 Pages : 284-288

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Journal Article] Quinotrierixin Inhibits ER Stress-induced XBP1 mRNA Splicing through Inhibition of Protein Synthesis2011
    • Author(s)
      Yamamoto K, Tashiro Eand Imoto M
    • Journal Title

      Biosci. Biotechnol. Biochem.

      Volume : 75 Pages : 284-288

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Journal Article] Involvement of 14-3-3 proteins in the second EGF-induced wave of Rac1 activation in the process of cell migration2011
    • Author(s)
      Kobayashi1 H, Ogura, Y, Sawada M, Nakayama T, Takano K, Minato Y, Takemoto Y, Tashiro E, Watanabe H & Imoto M
    • Journal Title

      J. Biol. Chem

      Volume : 286 Pages : 39259-39268

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Journal Article] Caffeine induces apoptosis by enhancement of autophagy via PI3K/Akt/mTOR/p70S6K inhibition.2011
    • Author(s)
      S.Saiki, Y.Sasazawa, Y.Imamichi, S.Kawajiri, T.Fujimaki, I.Tanida, H.Kobayashi, F.Sato, S.Sato, K.Ishikawa, M.Imoto, N.Hattori
    • Journal Title

      Autophagy

      Volume : 7 Pages : 42-53

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Isolation and structure elucidation of a novel androgen antagonist, arabilin, produced by Streptomyces sp.MK756-CF12010
    • Author(s)
      T.Kawamura, T.Fujimaki, N.Hamanaka, K.Torii, H.Kobayashi, Y.Takahashi, M.Igarashi, N.Kinoshita, Y.Nishimura, E.Tashiro, M.Imoto
    • Journal Title

      J.Antibiot(Tokyo) 63

      Pages : 601-605

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Journal Article] Glyoxalase-I is a novel target against Bcr-Abl+leukemic cells acquiring stem-like characteristics in hypoxic environment2010
    • Author(s)
      Takeuchi M, Kimura S, Kuroda J, Ashihara E, KawataniM, Osada H, Umezawa K, Yasui E, Imoto M, Tsuruo T, Yokota A, Tanaka R, Nagao T, Nakahata N, Fujiyama Y Maekawa T
    • Journal Title

      Cell Death Diff.

      Volume : 17 Pages : 1211-1220

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Metabolomic identification of the target of the filopodia protrusion inhibitor glucopiericidin A2010
    • Author(s)
      Kitagawa M, Ikeda S, Tashiro E, Soga T, Imoto M.
    • Journal Title

      Chemistry and Biology

      Volume : 17 Pages : 989-998

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Journal Article] Glyoxalase-I is a novel target against Bcr-Abl^+leukemic cells acquiring stem-like characteristics in hypoxic environment.2010
    • Author(s)
      Takeuchi M, Kimura S, Kuroda J, Ashihara E, KawataniM, Osada H, Umezawa K, Yasui E, Imoto M, Tsuruo T, Yokota A, Tanaka R, Nagao T, Nakahata N, Fujiyama Y Maekawa T
    • Journal Title

      Cell Death Diff

      Volume : 17 Pages : 1211-1220

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Journal Article] Terpenoids produced by actinomycetes: isolation, structural elucidation and biosynthesis of new diterpenes, gifhornenolones A and B from Verrucosispora gifhornensis YM28-0882010
    • Author(s)
      M. Shirai. M. Okuda, K. Motohashi, M. Imoto, K. Furihata, Y. Matsuo, A. Katsuta, Y. Shizuri, H. Seto
    • Journal Title

      J. Antibiot

      Volume : 63 Pages : 245-250

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Journal Article] Metabolomic identification of the target of the filopodia protrusion inhibitor glucopiericidin A2010
    • Author(s)
      Kitagawa M, Ikeda S, Tashiro E, Soga T, Imoto M
    • Journal Title

      Chemistry and Biology

      Volume : 17 Pages : 989-998

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Total Synthesis of Incednam, the Aglycon of Incednine.2010
    • Author(s)
      T. Ohtani, S. Tsukamoto, H. Kanda, K. Misawa, Y. Urakawa, T. Fujimaki, M. Imoto,Y. Takahashi, D. Takahashi†, and K. Toshima
    • Journal Title

      Org. Lett.

      Volume : 12 Pages : 5068-5071

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Journal Article] Isolation and structure elucidation of a novel androgen antagonist, arabilin, produced by Streptomycessp. MK756-CF12010
    • Author(s)
      Kawamura T, Fujimaki T, Hamanaka N, Torii K, Kobayashi H, Takahashi Y, Igarashi M, Kinoshita N, Nishimura Y, Tashiro E, Imoto M
    • Journal Title

      J. Antibiot.

      Volume : 63 Pages : 601-605

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Journal Article] Mesenchyme cells can function to induce epithelial cell proliferation in starfish embryos.2010
    • Author(s)
      G.Hamanaka, M.Matsumoto, M.Imoto, H.Kaneko
    • Journal Title

      Developmental Dynamics 293

      Pages : 818-827

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310146

  • [Journal Article] Mesenchyme cells can function to induce epithelial cell proliferation in starfish embryos.2010
    • Author(s)
      G.Hamanaka, M.Matsumoto, M.Imoto, H.Kaneko
    • Journal Title

      Developmental Dynamics 293

      Pages : 818-827

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20015043

  • [Journal Article] Isolation and structure elucidation of a novel androgen antagonist, arabilin, produced by Streptomyces sp.MK756-CF12010
    • Author(s)
      T.Kawamura, T.Fujimaki, N.Hamanaka, K.Torii, H.Kobayashi, Y.Takahashi, M.Igarashi, N.Kinoshita, Y.Nishimura, E.Tashiro, M.Imoto
    • Journal Title

      J.Antibiot(Tokyo)

      Volume : 63 Pages : 601-605

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Journal Article] Terpenoids produced by actinomycetes: isolation, structural elucidation and biosynthesis of new diterpenes2010
    • Author(s)
      M. Shirai. M. Okuda, K. Motohashi, M. Imoto, K. Furihata, Y. Matsuo, A. Katsuta, Y. Shizuri, H. Seto
    • Journal Title

      gifhornenolones A and B from Verrucosispora gifhornensis YM28-088.J. Antibiot.

      Volume : 63 Pages : 245-250

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Distinct subcellular localization in the cytosol and apicoplast, unexpected dimerization and inhibition of Plasmodium falciparum glyoxalases2010
    • Author(s)
      M. Urscher, JM. Przyborski, M. Imotoand M. Deponte.
    • Journal Title

      Mol Microbiol.

      Volume : 76 Pages : 92-103

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Mesenchyme cells can function to induce epithelial cell proliferation in starfish embryos.2010
    • Author(s)
      G. Hamanaka, M. Matsumoto, M. Imoto, H. Kaneko
    • Journal Title

      Develomental Dynamics 293

      Pages : 818-827

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310146

  • [Journal Article] Glyoxalase-I is a novel target against Bcr-Abl^+ leukemic cells acquiring stem-like characteristics in hypoxic environment.2010
    • Author(s)
      M.Takeuchi, S.Kimura, J.Kuroda, E.Ashihara, M.Kawatani, H.Osada, K.Umezawa, E.Yasui, M.Imoto, T.Tsuruo, A.Yokota, R.Tanaka, R.Nagao, T.Nakahata, Y.Fujiyama, T.Maekawa
    • Journal Title

      Cell Death Diff. (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310146

  • [Journal Article] Total Synthesis of Incednam, the Aglycon of Incednine2010
    • Author(s)
      T. Ohtani, S. Tsukamoto, H. Kanda, K. Misawa, Y. Urakawa, T. Fujimaki, M. Imoto,Y. Takahashi, D. Takahashi†, and K. Toshima
    • Journal Title

      Org. Lett

      Volume : 12 Pages : 5068-5071

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Mesenchyme cells can function to induce epithelial cell proliferation in starfish embryos2010
    • Author(s)
      G. Hamanaka, M. Matsumoto, M. Imotoand H. Kaneko:
    • Journal Title

      Develomental Dynamics

      Volume : 293 Pages : 818-827

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Metabolomic identification of the target of the filopodia protrusion inhibitor glucopiericidin A2010
    • Author(s)
      M.Kitagawa, S.Ikeda, E.Tashiro, T.Soga, M.Imoto
    • Journal Title

      Chemistry and Biology

      Volume : 17 Pages : 989-998

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Journal Article] Mesenchyme cells can function to induce epithelial cell proliferation in starfish embryos.2010
    • Author(s)
      G. Hamanaka, M. Matsumoto, M. Imotoand H. Kaneko
    • Journal Title

      Develomental Dynamics

      Volume : 293 Pages : 818-827

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Journal Article] Isolation and structure elucidation of a novel androgen antagonist2010
    • Author(s)
      Kawamura T, Fujimaki T, Hamanaka N, Torii K, Kobayashi H, Takahashi Y, Igarashi M, Kinoshita N, Nishimura Y, Tashiro E, Imoto M
    • Journal Title

      arabilin, produced by Streptomycessp. MK756-CF1. J. Antibiot.

      Volume : 63 Pages : 601-605

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Metabolomic identification of the target of the filopodia protrusion inhibitor glucopiericidin A2010
    • Author(s)
      M.Kitagawa, S.Ikeda, E.Tashiro, T.Soga, M.Imoto
    • Journal Title

      Chemistry and Biology 17

      Pages : 989-998

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Journal Article] Distinct subcellular localization in the cytosol and apicoplast, unexpected dimerization and inhibition of Plasmodium falciparum glyoxalases2010
    • Author(s)
      M. Urscher, JM. Przyborski, M. Imotoand M. Deponte
    • Journal Title

      Mol Microbiol.

      Volume : 76 Pages : 92-103

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Journal Article] Oligomycin induced the proteasomal degradation of cyclin D1 protein2009
    • Author(s)
      M.Kanai, S.Iba, R.Okada, E.Tashiro, M.Imoto
    • Journal Title

      J.Antibiot 62

      Pages : 425-429

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310146

  • [Journal Article] V-ATPase inhibitors overcome Bcl-xL-mediated chemoresistance throughrestoration of a caspase-independent apoptotic pathway2009
    • Author(s)
      Sasazawa Y, Futamura Y, Tashiro E, Imoto M.
    • Journal Title

      Cancer Sci 100

      Pages : 1460-1467

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17012025

  • [Journal Article] V-ATPase inhibitors overcome Bcl-xL-mediated chemoresistance through restoration of a caspase-independent apoptotic pathway.2009
    • Author(s)
      Y. Sasazawa, Y. Futamura, E. Tashiro, M. Imoto
    • Journal Title

      Cancer Science 100

      Pages : 1460-1467

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310146

  • [Journal Article] Transcriptional regulation of human fibroblast growth factor receptor 1 by E2F-1.2009
    • Author(s)
      M. Kanai, E. Tashiro, H. Maruki, Y. Minato, M. Imoto
    • Journal Title

      Gene 438

      Pages : 49-53

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310146

  • [Journal Article] Oligomycin induced the proteasomal degradation of cyclin D12009
    • Author(s)
      M.Kanai, S.Iba, R.Okada, E.Tashiro, M.Imoto
    • Journal Title

      J.Antibiot(Tokyo) 62

      Pages : 425-429

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Journal Article] Transcriptional regulation of human fibroblast growth factor receptor 1 by E2F-1.2009
    • Author(s)
      M.Kanai, E.Tashiro, H.Maruki, Y.Minato, M.Imoto
    • Journal Title

      Gene 438

      Pages : 49-56

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Journal Article] 微生物生理活性物質のケミカルバイオロジー2009
    • Author(s)
      田代悦, 井本正哉
    • Journal Title

      化学と生物 47

      Pages : 193-201

    • Data Source
      KAKENHI-PROJECT-20611016

  • [Journal Article] Transcriptional regulation of human fibroblast growth factor receptor 1 by E2F-12009
    • Author(s)
      M.Kanai, E.Tashiro, H.Maruki, Y.Minato, M.Imoto
    • Journal Title

      Gene 438

      Pages : 49-56

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Journal Article] V-ATPase inhibitors overcome Bcl-xL-mediated chemoresistance through restoration of a caspase-independent apoptotic pathway2009
    • Author(s)
      Sasazawa Y, Futamura Y, Tashiro E, Imoto M.
    • Journal Title

      Cancer Science 100

      Pages : 1460-1467

    • Data Source
      KAKENHI-PROJECT-17012025

  • [Journal Article] Oligomycin induced the proteasomal degradation of cyclin D1 protein.2009
    • Author(s)
      M. Kanai, S. Iba, R. Okada, E. Tashiro, M. Imoto
    • Journal Title

      J. Antibiot 62

      Pages : 425-429

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310146

  • [Journal Article] Sakakibara. Integrating statistical predictions and experimental verifications for enhancing protein-chemical interaction predictions in virtual screening.2009
    • Author(s)
      N. Nagamine, T. Shirakawa, Y. Minato, K. Torii, H. Kobayashi, M. Imoto, Y. Sakakibara
    • Journal Title

      PLos Comput Biol e1000397

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310146

  • [Journal Article] Oligomycin induced the proteasomal degradation of cyclin D12009
    • Author(s)
      M.Kanai, S.Iba, R.Okada, E.Tashiro, M.Imoto
    • Journal Title

      J.Antibot(Tokyo) 62

      Pages : 425-429

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Journal Article] V-ATPase Inhibitors Overcome Bcl-xL-mediated Chemoresistance through Restoration of a Caspase-independent Apoptotic Pathway2009
    • Author(s)
      Y.Sasazawa, Y.Futamura, E.Tashiro, M.Imoto
    • Journal Title

      Cancr Science 100

      Pages : 1460-1467

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Journal Article] V-ATPase Inhibitors Overcome Bcl-xL-mediated Chemoresistance through Restoration of a Caspase-independent Apoptotic Pathway2009
    • Author(s)
      Y.Sasazawa, Y.Futamura, E.Tashiro, M.Imoto
    • Journal Title

      Cancer Science 100

      Pages : 1460-1467

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Journal Article] Oligomycin induced the proteasomal degradation of cyclin D1 oprotein2009
    • Author(s)
      M.Kanai, S.Iba, R.Okada, E.Tashiro, M.Imoto
    • Journal Title

      J.Antibiot 62

      Pages : 425-429

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20015043

  • [Journal Article] Transcriptional regulation of human fibroblast growth factor receptorl by E2F-1.2009
    • Author(s)
      Kanai, M. Tashiro, E. Maruki, H. Minato, Y. Imoto, M.
    • Journal Title

      Gene (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17012025

  • [Journal Article] V-ATPase inhibitors overcome Bcl-xL-mediated chemoresistance through restoration of a caspase-independent apoptotic pathway.2009
    • Author(s)
      Sasazawa, Y. Futamura, Y. Tashiro, E. Imoto. M.
    • Journal Title

      Cancer science (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17012025

  • [Journal Article] SAR study of a Novel Triene-ansamycin Group Compound, Quinotrierixin, and Related Compounds, as Inhibitors of ER Stress-induced XBP1 Activation. I.Taxonomy, Fermentation, Isolation, and Biological activities and SAR study2008
    • Author(s)
      T.Kawamura, E.Tashiro, K.Yamamoto, K Shindo, M.Imoto
    • Journal Title

      J.Antibiot(Tokyo) 61

      Pages : 303-311

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Journal Article] Identification and characterization of mouse type II platelet-derived growth factor receptor a transcript.2008
    • Author(s)
      Y. Minato, et. al. and M. Imoto
    • Journal Title

      Biosci.Biotechnol.Biochem., 72

      Pages : 759-766

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310146

  • [Journal Article] The identification of an osteoclastogenesis inhibitor through the inhibition of glyoxalase I2008
    • Author(s)
      M. Kawatani, H. Okumura, K Honda, N. Kanoh, M. Muroi, N. Dohmae, M. Takami, M. Kitagawa, Y. Futamura, M. Imoto, H. Osada
    • Journal Title

      Proc. Natl. Acad. Sci. USA 105

      Pages : 11691-11696

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310146

  • [Journal Article] Discovery of Incednine as a Potent Modulator of the Anti-apoptotic Function of Bel-xL from Microbial Origin2008
    • Author(s)
      Y. Futamura, R. Sawa, Y. Umezawa, M. Igarashi, H. Nakamura, K. Hasegawa, M. Yamasaki, E. Tashiro, Y. Takahashi, Y. Akamatsu, M. Imoto
    • Journal Title

      J. Am. Chem. Soc. 130

      Pages : 1822-1823

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310146

  • [Journal Article] Discovery of Incednine as a Potent Modulator of the Anti-apoptotic Function of Bcl-xL from Microbial Origin2008
    • Author(s)
      Y.Futamura, R.Sawa, Y.Umezawa, M.Igarashi, H.Nakamura, K.Hasegawa, M.Yamasaki, E.Tashiro, Y.Takahashi, Y.Akamatsu, M.Imoto
    • Journal Title

      The Journal of American Chemical Society 130

      Pages : 1822-1823

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Journal Article] Identification and characterization of mouse type II platelet-derived growth factor receptor a transcript.2008
    • Author(s)
      Y. Minato, Y. Nihei, Y. Kodama, E. Tashiro, M. Kanai, M. Imoto
    • Journal Title

      Biosci. Biotechnol. Biochem. 72

      Pages : 759-766

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310146

  • [Journal Article] Discovery of Incednine as a Potent Modulator of the Anti-apoptotic Function of Bc1-xL from Microbial Origin2008
    • Author(s)
      Y. Futamura, R. Sawa, Y. Umezawa, M. Igarashi, H. Nakamura, K. Hasegawa, M. Yamasaki, E. Tashiro, Y. Takahashi, Y. Akamatsu, and M. Imoto
    • Journal Title

      J. Am. Chem. Soc 130

      Pages : 1822-1823

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20015043

  • [Journal Article] Discovery of Incednine as a Potent Modulator of the Anti-apoptotic Function of Bcl-xL from Microbial Origin.2008
    • Author(s)
      Y. Futamura, R. Sawa, Y. Umezawa, M. Igarashi, H. Nakamura, K. Hasegawa, M. Yamasaki, E. Tashiro, Y. Takahashi, Y. Akamatsu, M. Imoto
    • Journal Title

      J. Am. Chem. Soc. 130

      Pages : 1822-1823

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310146

  • [Journal Article] The identification of an osteoclastogenesis inhibitor through the inhibit ion of glyoxalase I2008
    • Author(s)
      M. Kawatani, H. Okumura, K Honda, N. Kanoh, M. Muroi, N. Dohmae, M. Takami, M. Kitagawa, Y. Futamura, M. Imoto, and H. Osada
    • Journal Title

      Proc. Natl. Acad. Sci. USA 105

      Pages : 11691-11696

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20015043

  • [Journal Article] Identification and characterization of mouse type II platelet-derived growth factor receptor a transcript2008
    • Author(s)
      Y. Minato, Y. Nihei, Y. Kodama, E. Tashiro, M. Kanai and M. Imoto
    • Journal Title

      Biosci. Biotechnol. Biochem 72

      Pages : 759-766

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20015043

  • [Journal Article] SAR Study of a Novel Triene-ansamycin Group Compound, Quinotrierixin, and Related Compounds, as Inhibitors of ER Stress-induced XBP1 Activation. II. Structure Elucidation.2008
    • Author(s)
      T. Kawamura, E. Tashiro, K. Shindo, M. Imoto
    • Journal Title

      J. Antibiot 61

      Pages : 312-317

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310146

  • [Journal Article] Identification and characterization of mouse type II platelet-derived growth factor receptor a transcript2008
    • Author(s)
      Y.Minato, Y.Nihei, Y.Kodama, E.Tashiro, M.Kanai, M.Imoto
    • Journal Title

      Biosci.Biotechnol.Biochem. 72

      Pages : 759-766

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Journal Article] Discovery of Incednine as a Potent Modulator of the Anti-apoptotic Function of Bcl-xL from Microbial Origin.2008
    • Author(s)
      Futamura, Y. Sawa, R. Umezawa, Y. Igarashi, M. Nakamura, H. Hasegawa, K. Yamasaki, M. Tashiro, E. Takahashi, Y. Akamatsu, Y.and Imoto, M.
    • Journal Title

      J. Am. Chem. Soc. (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17012025

  • [Journal Article] Discovery of Incednine as a Potent Modulator of the Anti-apoptotic Function of Bcl-xL from Microbial Origin.2008
    • Author(s)
      Y. Futamura, et. al., and M. Imoto
    • Journal Title

      J.Am.Chem.Soc 130

      Pages : 1822-1823

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310146

  • [Journal Article] Identification and characterization of mouse type II platelet-derived growth factor receptor α transcript.2008
    • Author(s)
      Y. Minato, Y. Nihei, Y. Kodama, E. Tashiro, M. Kanai, M. Imoto
    • Journal Title

      Biosci. Biotechnol. Biochem. 72

      Pages : 759-766

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310146

  • [Journal Article] SAR Study of a Novel Triene-ansamycin Group Compound, Quinotrierixin, and Related Compounds, as Inhibitors of ER Stress-induced XBP1 Activation. I. Taxonomy, Fermentation, Isolation, Biological Activities and SAR Study.2008
    • Author(s)
      T. Kawamura, E. Tashiro, K. Yamamoto, K. Shindo, M. Imoto
    • Journal Title

      J. Antibiot 61

      Pages : 303-311

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310146

  • [Journal Article] The identification of an osteoclastogenesis inhibitor through the inhibition of glyoxalase2008
    • Author(s)
      M. Kawatani, H. Okumura, K Honda, N. Kanoh, M. Muroi, N. Dohmae, M. Takami, M. Kitagawa, Y. Futamura, M. Imoto, H. Osada
    • Journal Title

      I. Proc. Natl. Acad. Sci. U S A 105

      Pages : 11691-11696

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310146

  • [Journal Article] SAR study of a Novel Triene-ansamycin Group Compound, Quinotrierixin, and Related Compounds, as Inhibitors of ER Stress-induced XBP1 Activation. II.Structure Elucidation2008
    • Author(s)
      T.Kawamura, E.Tashiro, K.Shindo, M.Imoto
    • Journal Title

      J.Antibiot(Tokyo) 61

      Pages : 312-317

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Journal Article] Synthesis and antitumor activity of combretastatin D-4.2008
    • Author(s)
      K. Uno, T. Tanabe, T. Ogamino, R. Okada, M. Imoto, S. Nishiyama
    • Journal Title

      Heterocycles 75

      Pages : 291-296

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310146

  • [Journal Article] The identification of anosteoclastogenesis inhibitor through the inhibition of glyoxalase I.2008
    • Author(s)
      Kawatani M, Okumura H, Honda K, Kanoh N, Muroi M, Dohmae N, Takami M, Kitagawa M, Futamura Y, Imoto M, Osada H.
    • Journal Title

      Proc Natl Acad Sci, USA 105

      Pages : 11691-11696

    • Data Source
      KAKENHI-PROJECT-17012025

  • [Journal Article] Promotion of glioma cell survival by acyl-CoA synthetase 5 under extracellular acidosis conditions.2008
    • Author(s)
      Mashima, T. Sato, S. Sugimoto, Y. Tsuruo, T. Seimiya, H.
    • Journal Title

      Oncogene 28

      Pages : 9-19

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17012025

  • [Journal Article] Functions of cyclin D1 as an oncogene and regulation of cyclin D1 expression.2007
    • Author(s)
      E. Tashiro, A. Tsuchiya, M. Imoto
    • Journal Title

      Cancer Science 98

      Pages : 629-635

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310146

  • [Journal Article] Functions of cyclin D1 as an oncogene and regulation of cyclin D1 expression2007
    • Author(s)
      Tashiro, E., Tsuchiya, A., Imoto M.
    • Journal Title

      Cancer Science (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16300095

  • [Journal Article] Involvement of PP2A nuclear accumulation and subsequent inactivation of AP-1 in leptomycin B-inhibited cyclin D1 expression2007
    • Author(s)
      Tsuchiya, A., Tashiro, E., Yoshida, M., Imoto, M.
    • Journal Title

      Oncogene 26

      Pages : 1522-1532

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16300095

  • [Journal Article] Involvement of PP2A nuclear accumulation and subsequent inactivation of AP-1 in leptomycin B-inhibited cyclin D1 expression.2007
    • Author(s)
      Tsuchiya, A. Tashiro, E. Yoshida, M. and Imoto, M.
    • Journal Title

      Oncogene 26

      Pages : 1522-1532

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17012025

  • [Journal Article] Functions of cyclin D1 as an oncogene and regulation of cyclin D1 expression2007
    • Author(s)
      Tashiro, E., Tsuchiya, A., Imoto M.
    • Journal Title

      Cancer Science, (in press)

    • Data Source
      KAKENHI-PROJECT-16300095

  • [Journal Article] Transcriptional regulation of a new variant of human platelet-derived growth factor receptor a transcript by E2F-1.2007
    • Author(s)
      Y. Minato, E. Tashiro, M. Kanai, Y. Nihei, Y. Kodama, M. Imoto
    • Journal Title

      Gene 403

      Pages : 89-97

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310146

  • [Journal Article] Involvement of PP2A nuclear accumulation and subsequent inactivation of AP-1 in leptomycin B-inhibited cyclin D1 expression.2007
    • Author(s)
      Tsuchiya, A., Tashiro, E., Yoshida, M., Imoto, M.
    • Journal Title

      Oncogene. 26

      Pages : 1522-1532

    • Data Source
      KAKENHI-PROJECT-17012025

  • [Journal Article] Common Peak Approach Using Mass Spectrometry Data Sets for Predicting the Effects of Anticancer Drugs on Breast Cancer.2007
    • Author(s)
      Ushijima, M. Miyata, S. Eguchi, S. Kawakita, M. Yoshimoto, M. Iwase, T. Akiyama, F. Sakamoto, G. Nagasaki, K. Miki, Y. Noda, T. Hoshikawa, Y and Matsuura. M.
    • Journal Title

      Cancer Informatics. 3

      Pages : 285-293

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17012025

  • [Journal Article] Trierixin,a Novel Inhibitor of ER stress-induced XBP1 Activation from Streptomyces sp.I.Taxonomy,Fermentation,Isolation,and Biological activides.2007
    • Author(s)
      E. Tashiro, et. al. and M. Imoto:
    • Journal Title

      J.Antiobiot 60

      Pages : 547-553

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310146

  • [Journal Article] Common peak approach by semi-supervised learning using mass spectrometry datasets for predicting effects on anticancer drugs on breast cancer2007
    • Author(s)
      Ushijima M, Miyata S, Eguchi S, Kawakita M, Yoshimoto M, Iwase T, Akiyama F, Sakamoto G, Nagasaki K, Miki Y, Noda T, Hoshikawa Y, Matsuura M.
    • Journal Title

      Cancer Informatics 3

      Pages : 285-93

    • Data Source
      KAKENHI-PROJECT-17012025

  • [Journal Article] Trierixin, a Novel Inhibitor of ER Stress-induced XBP1 Activation from Streptomyces sp. II. Structure Elucidation2007
    • Author(s)
      Y. Futamura, E. Tashiro, N. Hironiwa, J. Kohno, M. Nishio, K. Shindo, M. Imoto
    • Journal Title

      J. Antiobiot 60

      Pages : 582-585

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310146

  • [Journal Article] Trierixin, a Novel Inhibitor of ER stress-induced XBP1 Activation from Streptomyces sp. I. Taxonomy, Fermentation, Isolation, and Biological activities.2007
    • Author(s)
      E. Tashiro, N. Hironiwa, M. Kitagawa, Y. Futamura, M. Imoto
    • Journal Title

      J. Antiobiot 60

      Pages : 547-553

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310146

  • [Journal Article] Involvement of PP2A nuclear accumulation and subsequent inactivation of AP-1 in leptomycin B-inhibited cyclin D1 expression.2007
    • Author(s)
      A. Tsuchiya, E. Tashiro, M. Yoshida, M. Imoto
    • Journal Title

      Oncogene 26

      Pages : 1522-1532

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310146

  • [Journal Article] Design, synthesis, and evaluation of cyclic amide/imide-bearing hydroxamic acid derivatives as class-selective histone deacetylase(HDAC)inhibitors.2006
    • Author(s)
      Shinji, C., Maeda, S., Imai, K., Yoshida, M., Hashimoto, Y., Miyachi, H.
    • Journal Title

      Bioorg Med Chem. 14

      Pages : 7625-7651

    • Data Source
      KAKENHI-PROJECT-17012025

  • [Journal Article] Antitumor effect of kigamicin D on mouse tumor models.2006
    • Author(s)
      Masuda, T., Ohba, S., Kawada, M., Osono, M., Ikeda, D., Esumi, H., Kunimoto, S.
    • Journal Title

      J Antibiot 59

      Pages : 209-214

    • Data Source
      KAKENHI-PROJECT-17012025

  • [Journal Article] Modification of pyrimidine derivatives from antiviral agents to antitumor agents.2006
    • Author(s)
      Kimura, H., Katoh, T., Kajimoto, T., Node, M., Hisaki, M., Sugimoto, Y., Majima, T., Uehara, Y., Yamori, T.
    • Journal Title

      Anticancer Res. 26

      Pages : 91-97

    • Data Source
      KAKENHI-PROJECT-17012025

  • [Journal Article] Suppression of multidrug resistance by migrastatin.2006
    • Author(s)
      Takemoto, Y., Tashiro, E., Imoto, M.
    • Journal Title

      J. Antibiot. 59

      Pages : 435-438

    • Data Source
      KAKENHI-PROJECT-17012025

  • [Journal Article] Chemistry and Biology of Moverastins, inhibitors of cancer cell migration, produced by Aspergillus2005
    • Author(s)
      Y.Takemoto, H.Watanabe, K.Uchida, K.Matsumura, K.Nakae, E.Tashiro, K.Shindo, T.Kitahara, M.Imoto
    • Journal Title

      Chemistry ＆ Biology 12・12

      Pages : 1337-1347

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16300095

  • [Journal Article] GSK-3 directly phosphorylates and activates MARK2/PAR-12005
    • Author(s)
      S.Kosuga, E.Tashiro, T.Kajioka, M.Ueki, Y.Shimizu, M.Imoto
    • Journal Title

      Journal of Biological Chemistry 280・52

      Pages : 42715-42722

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16300095

  • [Journal Article] Synthesis of the naphthalene-derived inhibitors against Cdc25A dual-specificity protein phosphatase and their biological activity2005
    • Author(s)
      A.Shinbashi, A.Tsuchiya, M.Imoto, S.Nishiyama
    • Journal Title

      Bioorganic & Medicinal Chemistry Letters 15

      Pages : 61-65

    • Data Source
      KAKENHI-PROJECT-15650054

  • [Journal Article] Chemistry and Biology of Moverastins, inhibitors of cancer cell migration, produced by Aspergillus2005
    • Author(s)
      Y.Takemoto, H.Watanabe, K.Uchida, K.Matsumura, K.Nakae, E.Tashiro, K.Shindo, T.Kitahara, M.Imoto
    • Journal Title

      Chemistry ＆ Biology 12(12)

      Pages : 1337-1347

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16300095

  • [Journal Article] Synthesis of the naphthalene-derived inhibitors against Cdc25A dual-specificity protein phosphatase and their biological activity2005
    • Author(s)
      A.Shinbashi, A.Tsuchiya, M.Imoto, S.Nishiyama
    • Journal Title

      Bioorganic & Medicinal Chemistry Letters 15

      Pages : 61-65

    • Data Source
      KAKENHI-PROJECT-12217133

  • [Journal Article] Synthesis of the naphthalene-derived inhibitors against Cdc25A dual-specificity protein phosphatase and their biological activity2005
    • Author(s)
      A.Shinbashi, A.Tsuchiya, M.Imoto, S.Nishiyama
    • Journal Title

      Bioorganic ＆ Medicinal Chemistry Letters 15

      Pages : 61-65

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16300095

  • [Journal Article] Synthesis of the naphthalene-derived inhibitors against Cdc25A dual-specificity protein phosphatase and their biological activity2005
    • Author(s)
      A.Shinbashi, A.Tsuchiya, M.Imoto, S.Nishiyama
    • Journal Title

      Bioorganic & Medicinal Chemistry Letters 15

      Pages : 61-65

    • Data Source
      KAKENHI-PROJECT-16300095

  • [Journal Article] Synthesis of the naphthalene-derived inhibitors against Cdc25A dual-specificity protein phosphatase and their biological activity2005
    • Author(s)
      A.Shinbashi, A.Tsuchiya, N.Imoto, S.Nishiyama
    • Journal Title

      Bioorganic ＆ Medicinal Chemistry Letters 15

      Pages : 61-65

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16300095

  • [Journal Article] Design and synthesis of phthalimide-type histone deacetylase2005
    • Author(s)
      Shinji, C., Nakamura, T., Maeda, S., Yoshida, M., Hashimoto, Y., Miyachi, H
    • Journal Title

      Bioorg.Med.Chem.Lett. 15(20)

      Pages : 4427-4431

    • Data Source
      KAKENHI-PROJECT-17012025

  • [Journal Article] GSK-3 directly phosphorylates and activates MAR K2/PAR-12005
    • Author(s)
      S.Kosuga, E.Tashiro, T.Kajioka, M.Ueki, Y.Shimizu, M.Imoto
    • Journal Title

      Journal of Biological Chemistry 280(52)

      Pages : 42715-42722

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16300095

  • [Journal Article] Chemistry and Biology of Moverastins, inhibitors of cancer cell migration, produced by Aspergillus2005
    • Author(s)
      Takemoto Y, Watanabe H, Uchida K, Matsumura K, Nakae K, Tashiro E, Shindo K, Kitahara T, Imoto M.
    • Journal Title

      Chem.Biol. 12(12)

      Pages : 1337-1347

    • Data Source
      KAKENHI-PROJECT-17012025

  • [Journal Article] Chemistry and Biology of Moverastins, inhibitors of cancer cell migration, produced by Aspergillus2005
    • Author(s)
      Y.Takemoto, H.Watanabe, K.Uchida, K.Matsumura, K.Nakae, E.Tashiro, K.Shindo, T.Kitahara, M.Imoto
    • Journal Title

      Chemistry & Biology 12・12

      Pages : 1337-1347

    • Data Source
      KAKENHI-PROJECT-16300095

  • [Journal Article] The synthesis amd Biological activity of pyranonaphthoquione derivative from Streptomyces sp.And their related substances2004
    • Author(s)
      A.Shinbashi, A.Tsuchiya, M.Imoto, S.Nishiyama
    • Journal Title

      Bull.Chem.Soc.Japan 77

      Pages : 1925-1930

    • Data Source
      KAKENHI-PROJECT-12217133

  • [Journal Article] The synthesis and Biological activity of pyranonaphthoquione derivatives from Streptomyces sp. and their related substances2004
    • Author(s)
      A.Shinbashi, A.Tsuchiya, M.Imoto, S.Nishiyama
    • Journal Title

      Bull. Chem. Soc. Japan 77

      Pages : 1925-1930

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16300095

  • [Journal Article] The synthesis amd Biological activity of pyranonaphthoquione derivatives from Streptomyces sp.And their related substances.2004
    • Author(s)
      A.Shinbashi, A.Tsuchiya, M.Imoto, S.Nishiyama
    • Journal Title

      Bull.Chem.Soc.Japan 77

      Pages : 1925-1930

    • Data Source
      KAKENHI-PROJECT-15650054

  • [Journal Article] The synthesis and Biological activity of pyranonaphthoquione derivatives from Streptomyces sp. and their related substances2004
    • Author(s)
      A.Shinbashi, A.Tsuchiya, M.Imoto, S.Nishiyama
    • Journal Title

      Bull.Chem.Soc.Japan 77

      Pages : 1925-1930

    • Data Source
      KAKENHI-PROJECT-16300095

  • [Journal Article] Glyoxalase-I is a novel target against Bcr-Abl^+ leukemic cells acquiring stem-like characteristics in hypoxic environment.
    • Author(s)
      M.Takeuchi, S.Kimura, J.Kuroda, E.Ashihara, M.Kawatani, H.Osada, K.Umezawa, E.Yasui, M.Imoto, T.Tsuruo, A.Yokota, R.Tanaka, R.Nagao, T.Nakahata, Y. Fujiyama, T.Maekawa
    • Journal Title

      Cell Death Diff. (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20015043

  • [Journal Article] Glyoxalase-I is a novel target against Bcr-Abl+ leukemic cells acquiring stem-like characteristics in hypoxic environment.
    • Author(s)
      M. Takeuchi, S. Kimura, J. Kuroda, E. Ashihara, M. Kawatani, H. Osada, K. Umezawa, E. Yasui, M. Imoto, T. Tsuruo, A. Yokota, R. Tanaka, R. Nagao, T. Nakahata, Y. Fujiyama, T. Maekawa
    • Journal Title

      Cell Death Diff. (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310146

  • [Journal Article] Novel derivatives of aclacinomycin A block cancer cell migration through inhibition of farnesyl transferase.
    • Author(s)
      Magi S, Shitara T, Takemoto Y, Sawada M, Kitagawa M, Tashiro E. Takahashi Y, Imoto M
    • Journal Title

      J. Antibiot

      Volume : (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Journal Article] Novel derivatives of aclacinomycin A block cancer cell migration through inhibition of farnesyl transferase
    • Author(s)
      Magi S, Shitara T, Takemoto Y, Sawada M, Kitagawa M, Tashiro E. Takahashi Y, Imoto M
    • Journal Title

      J. Antibiot

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Presentation] ケミカルゲノミクスによるオートファジー制御機構の解析2018
    • Author(s)
      片浦哲志、井本正哉
    • Organizer
      先端モデル動物支援プラットフォーム成果発表会
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] Synthetic lethal killing of β-catenin mutant cancer cells by small molecules2017
    • Author(s)
      Masaya Imoto
    • Organizer
      3rd KRIBB-RIKEN Chemical Biology Joint Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-17H06401

  • [Presentation] シスプラチン持続暴露によるEMT誘導機構の解析2017
    • Author(s)
      田代悦、井本正哉
    • Organizer
      第21回日本がん分子標的治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-15H03116

  • [Presentation] 細胞内ビリルビン量を指標とするパーキンソン病治療薬の探索2017
    • Author(s)
      片浦哲志、斉木臣二、井本正哉
    • Organizer
      先端モデル動物支援プラットフォーム若手支援技術講習会
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] An easy and high efficient technique for mouse genome manipulation by electroporation.2017
    • Author(s)
      Michihiko Sugimoto, Daisuke Ariyasu, Kei-ichiro Ishiguro, Shingo Ito, Kimi Araki.
    • Organizer
      2017 ASMRA & AMPC meeting.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] Synthetic lethal killing of b-catenin mutant cancer cells by small molecules2017
    • Author(s)
      井本正哉
    • Organizer
      3rd KRIBB-RIKEN Chemical Biology Joint Symposium
    • Int'l Joint Research / Invited
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] Synthetic lethal killing of b-catenin mutant cancer cells by small molecules2017
    • Author(s)
      井本正哉
    • Organizer
      3rd KRIBB-RIKEN Chemical Biology Joint Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H03116

  • [Presentation] シスプラチン持続暴露によるEMT誘導機構の解析2017
    • Author(s)
      田代悦、井本正哉
    • Organizer
      第21回日本がん分子標的治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] 細胞形態・表現型解析による分子プロファイリング2017
    • Author(s)
      井本正哉
    • Organizer
      先端モデル動物支援プラットフォーム平成29年度若手支援技術講習会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] Screening of the compounds that modulate cellular bilirubin level in hepatocellular carcinoma HepG2 cells2017
    • Author(s)
      片浦哲志、井本正哉
    • Organizer
      The AACR-NCI-EORTC International Conference on "Molecular Targets and Cancer Therapeutics : Discovery, Biology, and Clinical Applications 2017"
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] Screening of the compounds that modulate cellular bikirubin level in hepatocellular carcinoma HepG2 cells2017
    • Author(s)
      片浦哲志、井本正哉
    • Organizer
      AACR-NCI-EORTC International Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H03116

  • [Presentation] βカテニン変異がん細胞に合成致死を誘導する化合物の探索2017
    • Author(s)
      井本正哉
    • Organizer
      第76回日本癌学会学術総会
    • Invited
    • Data Source
      KAKENHI-PLANNED-17H06401

  • [Presentation] 謎解きと宝探しの天然物ケミカルバイオロジー2017
    • Author(s)
      井本正哉
    • Organizer
      第52回天然物化学談話会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] 謎解きと宝探しの天然物ケミカルバイオロジー2017
    • Author(s)
      井本正哉
    • Organizer
      第52回天然物化学談話会
    • Invited
    • Data Source
      KAKENHI-PLANNED-17H06401

  • [Presentation] Screening of the compounds that modulate cellular bilirubin level in hopatocellular carcinoma HepG2 cells2017
    • Author(s)
      片浦哲志、井本正哉
    • Organizer
      AACR-NCI-EORTC International Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] 謎解きと宝探しの天然物ケミカルバイオロジー2017
    • Author(s)
      井本正哉
    • Organizer
      第52回天然物化学談話会
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H03116

  • [Presentation] Mitochondrial uncoupler exerts a synthetic lethal effect against beta-catenin mutant tumor cells2017
    • Author(s)
      井本正哉
    • Organizer
      Asian Chemical Biology Initiative 2017 Ho Chi Minh Meeting
    • Place of Presentation
      Ho Chi Minh （Vietnam）
    • Year and Date
      2017-01-21
    • Int'l Joint Research / Invited
    • Data Source
      KAKENHI-PROJECT-15H03116

  • [Presentation] β-catenin変異型がん細胞選択的に細胞死を誘導する化合物の探索2016
    • Author(s)
      池田拓慧、田代悦、井本正哉
    • Organizer
      日本農芸化学会2016年度大会
    • Place of Presentation
      札幌コンベンションセンター（北海道・札幌市）
    • Year and Date
      2016-03-29
    • Data Source
      KAKENHI-PROJECT-15H03116

  • [Presentation] ミトコンドリア脱共役剤ノナクチンによるβ-catenin変異がんに対する合成致死誘導2016
    • Author(s)
      四方雄貴、木我真基、田代悦、井本正哉
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜（神奈川県・横浜市）
    • Year and Date
      2016-10-06
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H03116

  • [Presentation] シスプラチン耐性細胞におけるROCKによるE-cadherin発現制御2016
    • Author(s)
      田代悦、今辻沙也佳、井本正哉
    • Organizer
      日本癌学会
    • Place of Presentation
      パシフィコ横浜（神奈川県・横浜市）
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-26350974

  • [Presentation] メラノーマ治療薬として開発されたMEK阻害剤の大腸がん治療薬としての可能性2016
    • Author(s)
      四方雄貴、木我真基、田代悦、井本正哉
    • Organizer
      日本薬学会第136回年会
    • Place of Presentation
      パシフィコ横浜（神奈川県・横浜市）
    • Year and Date
      2016-03-27
    • Data Source
      KAKENHI-PROJECT-15H03116

  • [Presentation] Targeting distant metastasis of colorectal cancer with a combination of anti-claudin-4 antibody2016
    • Author(s)
      Fujiwara R, Luo Y, Sasaki T, Nishiguchi Y, Ohmori H, Hashimoto Y, Kondo M, Kuniayasu H
    • Organizer
      76th Annual Meeting of Japanese Association for Cancer
    • Place of Presentation
      バシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] ホルモン療法抵抗性前立腺がんに対する天然物創薬研究2016
    • Author(s)
      齋藤駿、藤巻貴宏、田代悦、五十嵐康弘、井本正哉
    • Organizer
      日本薬学会第136回年会
    • Place of Presentation
      パシフィコ横浜（神奈川県・横浜市）
    • Year and Date
      2016-03-28
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Presentation] 合成致死を利用したβ-catenin変異がんに対する治療薬シードの探索2016
    • Author(s)
      四方雄貴、木我真基、田代悦、井本正哉
    • Organizer
      第20回日本がん分子標的治療学会学術集会
    • Place of Presentation
      別府国際コンベンションセンター（大分県・別府市）
    • Year and Date
      2016-05-31
    • Data Source
      KAKENHI-PROJECT-15H03116

  • [Presentation] 新規発光物質の開発を目的としたホタルルシフェリンアナログの合成と活性評価2016
    • Author(s)
      井岡秀二、斉藤毅、岩野智、鈴木孝治、井本正哉、西山繁
    • Organizer
      日本化学会第96回春季年会（2016)
    • Place of Presentation
      同志社大学（京都府・京都市）
    • Year and Date
      2016-03-24
    • Data Source
      KAKENHI-PROJECT-15H03116

  • [Presentation] Cisplatin持続暴露によるEMT誘導機構2016
    • Author(s)
      今辻紗也佳、大嶽弘之、奈良部進、田代悦、井本正哉
    • Organizer
      日本農芸化学会2016年度大会
    • Place of Presentation
      札幌コンベンションセンター（北海道・札幌市）
    • Year and Date
      2016-03-29
    • Data Source
      KAKENHI-PROJECT-26350974

  • [Presentation] MEK阻害剤はベータカテニン変異細胞選択的にアポトーシスを誘導する2016
    • Author(s)
      井本正哉
    • Organizer
      第68回日本細胞生物学会大会
    • Place of Presentation
      京都テルサ テルサホール（京都府・京都市）
    • Year and Date
      2016-06-17
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H03116

  • [Presentation] 放線菌由来新規アンドロゲン受容体アンタゴニスト Antarlide 類の単離・構造決定及び生物活性2015
    • Author(s)
      齋藤駿、藤巻貴宏、田代悦、五十嵐康弘、井本正哉
    • Organizer
      第57回天然有機化合物討論会
    • Place of Presentation
      神奈川県民ホール（神奈川県・横浜市）
    • Year and Date
      2015-09-10
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Presentation] Chemistry and biology of natural products that modulate cellular responses2015
    • Author(s)
      Masaya Imoto
    • Organizer
      SIBM Natural Products 2015
    • Place of Presentation
      San Diego, CA USA
    • Year and Date
      2015-01-12
    • Invited
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Presentation] 抗がん剤耐性とEMTの関係に着目したMET誘導物質の探索系構築2015
    • Author(s)
      田代悦，大嶽弘之，奈良部進，井本正哉
    • Organizer
      日本農芸化学会
    • Place of Presentation
      岡山大学 津島キャンパス（岡山県岡山市）
    • Year and Date
      2015-03-27
    • Data Source
      KAKENHI-PROJECT-26350974

  • [Presentation] エストロゲン受容体制御分子BIG3を標的とした新規ER陽性乳がん治療法2015
    • Author(s)
      吉丸哲郎、小松正人、田代　悦、長田裕之、井本正哉、豊國伸哉、三好康雄、笹　三徳、片桐豊雅
    • Organizer
      第７４回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場、愛知県名古屋市
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Presentation] Identification of licopyranocoumarin and glycyrurol from herbal medicines as neuroprotective compounds for parkinson's disease2015
    • Author(s)
      M.Imoto, T.Fujimaki, S.Saiki, E.Tashiro, D.Yamada, N.Hattori
    • Organizer
      PACIFICHEM 2015
    • Place of Presentation
      ホノルル（米国）
    • Year and Date
      2015-12-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H03116

  • [Presentation] 生体内フリーラジカルの検出を目的とした新規ホタルルシフェリンアナログの開発2015
    • Author(s)
      井岡秀二、斉藤毅、岩野智、牧昌次郎、丹羽治樹、井本正哉、西山繁
    • Organizer
      日本ケミカルバイオロジー第10回年会
    • Place of Presentation
      東北大学川内キャンパス（宮城県・仙台市）
    • Year and Date
      2015-06-11
    • Data Source
      KAKENHI-PROJECT-15H03116

  • [Presentation] 微生物由来天然化合物の治療薬シードへの展開2015
    • Author(s)
      井本正哉、田代悦
    • Organizer
      日本農芸化学会2015年度大会
    • Place of Presentation
      岡山大学 津島キャンパス（岡山県岡山市）
    • Year and Date
      2015-03-29
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Presentation] カリウムイオノフォアであるNonactinはβ-catenin変異がん選択的に細胞死を誘導する2015
    • Author(s)
      四方雄貴、田代悦、井本正哉
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場（愛知県・名古屋市）
    • Year and Date
      2015-10-09
    • Data Source
      KAKENHI-PROJECT-15H03116

  • [Presentation] β-catenin変異型がん細胞選択的に細胞死を誘導する化合物の探索2015
    • Author(s)
      池田拓慧、四方雄貴、田代悦、井本正哉
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場（愛知県・名古屋市）
    • Year and Date
      2015-10-09
    • Data Source
      KAKENHI-PROJECT-15H03116

  • [Presentation] Association of an EPAS1 gene polymorphism with susceptibility to lung adenocarcinoma in female Japanese non-smokers2015
    • Author(s)
      Hidetaka Eguchi, Shinichi Iwamoto, Yumi Nishio, Andica Chandra Putra, Hiroshi Fuchita, Miki Ohe, Akihisa Sutani, Takashige Kuraki, Keiko Hiyama, Isao Murakami, Keiji Tanimoto, Takeshi Isobe
    • Organizer
      第25回日本疫学会学術総会
    • Place of Presentation
      ウインクあいち(愛知県・名古屋市)
    • Year and Date
      2015-01-23
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Presentation] CDDP耐性細胞におけるTGF-β受容体阻害剤によるMET誘導2015
    • Author(s)
      今辻紗也佳、田代悦、井本正哉
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場（愛知県・名古屋市）
    • Year and Date
      2015-10-09
    • Data Source
      KAKENHI-PROJECT-26350974

  • [Presentation] Isolation and biological activities of novel androgen receptor antagonist produced by Streptomyces2015
    • Author(s)
      S.Saito, T.Fujimaki, E.Tashiro, Y.Igarashi, M.Imoto
    • Organizer
      PACIFICHEM 2015
    • Place of Presentation
      ホノルル（米国）
    • Year and Date
      2015-12-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Presentation] ケミカルジェネティクスによるホヤ脊索管形成機構の解析2014
    • Author(s)
      溝谷優治、堀田耕司、岡浩太郎、柴小菊、稲葉一男、鈴木麻友、田代悦、井本正哉
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      国立京都国際会館（京都府京都市）
    • Year and Date
      2014-10-18
    • Data Source
      KAKENHI-PROJECT-25560419

  • [Presentation] Xanthohumol impairs autophagosome maturation through direct inhibition of Valosin-containing protein2014
    • Author(s)
      井本正哉
    • Organizer
      RIKEN-Max Planck Joint Research Center for Systems Chemical Biology 3rd Annual Symposium
    • Place of Presentation
      Schloss Ringberg, Germany
    • Year and Date
      2014-05-22
    • Invited
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Presentation] Establishment of a New Detection System for the Dimerization of IRE1a Using a BiFC Assay2014
    • Author(s)
      Etsu Tashiro, Satoko Shinjo, Masaya Imoto
    • Organizer
      7th The Japan-Korea Chemical Biology Symposium
    • Place of Presentation
      韓国チェジュ島
    • Year and Date
      2014-02-10
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Presentation] 化合物活性予測のための遺伝子発現データベース構築2014
    • Author(s)
      田代悦、大嶽弘之、井本正哉
    • Organizer
      文科省新学術領域研究・がん支援「化学療法基盤支援活動」第三回シンポジウムアカデミアからの抗がん剤創薬に向けて-天然物の有効利用
    • Place of Presentation
      万国津梁館(沖縄県・名護市)
    • Year and Date
      2014-05-12
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Presentation] The association of alcohol intake with serum lipid profile and its modification by ADH1B and ALDH2 polymorphisms : J-MICC Study2014
    • Author(s)
      Sasakabe T, Guang Y, Naito M, Morita E, Kawai S, Okada R, Tamura T, Nakagawa H, Suma S, Fukuda N, Sugimoto Y, Wakai K, Hamajima N
    • Organizer
      The 20th IEA World Congress of Epidemiology
    • Place of Presentation
      Anchorage, Alaska, U.S.A.
    • Year and Date
      2014-08-17
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Presentation] 種々の化合物によるUPR関連遺伝子群発現挙動の解析2014
    • Author(s)
      田代悦、新荘聡子、溝谷優治、井本正哉
    • Organizer
      日本農芸化学会
    • Place of Presentation
      明治大学生田キャンパス
    • Year and Date
      2014-03-28
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Presentation] HDAC阻害剤SAHAによるMET誘導2014
    • Author(s)
      田代悦，井本正哉
    • Organizer
      日本がん分子標的治療学会
    • Place of Presentation
      仙台市情報・産業プラザ（宮城県仙台市）
    • Year and Date
      2014-06-26
    • Data Source
      KAKENHI-PROJECT-26350974

  • [Presentation] Isoflavones in Japanese and Caucasian men with prostate cancer in Hawaii2014
    • Author(s)
      Fukagai T, Akaza H, Ogawa Y, Carlile R, Namiki T, Lederer JL, Maskarinec G, Tsuji H, Moriyama K, Fujimoto K, Hirao Y, Namiki M
    • Organizer
      2014 Genitourinary Cancer Symposium
    • Place of Presentation
      San Francisco, USA
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Presentation] Distinct patterns of RHOA mutations in Adult T-Cell Leukemia/Lymphoma and peripheral T-Cell lymphomas2014
    • Author(s)
      Nagata Y, Enami T, Sakata-Yanagimoto M, Kataoka K, Kitanaka A, Sato A, Shiraishi Y, Chiba K, Tanaka H, Shiozawa Y, Yoshizato T, Kon A, Yoshida K, Sanada M, Ishiyama K, Miyawaki S, Ishii R, Nureki O, Miyano S, Shimoda K, Watanabe T, Chiba S, Ogawa S
    • Organizer
      第76回日本血液学会学術集会
    • Place of Presentation
      大阪国際会議場(大阪府・大阪市)
    • Year and Date
      2014-11-01
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Presentation] Dysphagia and dietary intake of Japanese adults : the Shizuoka area in a Japanese multi-institutional collaborative cohort study2014
    • Author(s)
      Naito M, Wakai K, Kawai S, Nakagawa H, Tamura T, Suma S, Sugimoto Y, Fukuda N, Sasakbe T, Okada R, Morita E, Asai Y, Mori A, Hamajima N
    • Organizer
      The 20th IEA World Congress of Epidemiology
    • Place of Presentation
      Anchorage, Alaska, U.S.A.
    • Year and Date
      2014-08-19
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Presentation] Novel Biological Effects and Distinct Patterns of Rhoa Mutations in Adult T-Cell Leukemia/Lymphoma and Angioimmunoblastic T Cell Lymphoma2014
    • Author(s)
      Nagata Y, Enami T, Kontani K, Kataoka K, Sakata-Yanagimoto M, Kitanaka A, Sato A, Shiraishi Y, Chiba K, Tanaka H, Shiozawa Y, Yoshizato T, Kon A, Yoshida K, Sanada M, Ishiyama K, Miyawaki S, Ishii R, Nureki O, Miyano S, Shimoda K, Watanabe T, Katada T, Chiba S, Ogawa S
    • Organizer
      56th of ASH Annual Meeting and Exposition
    • Place of Presentation
      Moscone Center, San Francisco, U.S.A.
    • Year and Date
      2014-12-07
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Presentation] Significant associations of abdominal obesity with LYPLAL1 polymorphism (rs4846567) among a general Japanese population : a cross-sectional study2014
    • Author(s)
      Takashi T, Morita E, Kawai S, Sasakabe T, Fukuda N, Sugimoto Y, Suma S, Mokuno J, Nakagawa H, Hishida A, Okada R, Naito M, Hamajima N, Wakai K
    • Organizer
      The 20th IEA World Congress of Epidemiology
    • Place of Presentation
      Anchorage, Alaska, U.S.A.
    • Year and Date
      2014-08-19
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Presentation] Xanthohumol Impairs Autophagosome Maturation through Direct Inhibition of Valosin-Containing Protein2014
    • Author(s)
      Masaya Imoto
    • Organizer
      Riken-MaxPlanck 3rd Annual Symposium
    • Place of Presentation
      Kreuth／German
    • Year and Date
      2014-05-23
    • Invited
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Presentation] Comparative Analysis of the Expression Patterns of UPR-Target Genes Caused by UPR-Inducing Compounds2014
    • Author(s)
      Etsu Tashiro, Satoko Shinjo, Yuji Mizotani, and Masaya Imoto
    • Organizer
      RIKEN-Max Planck Joint Research Center for Systems Chemical Biology 3rd Annual Symposium
    • Place of Presentation
      Schloss Ringberg ドイツ
    • Year and Date
      2014-05-22
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Presentation] 5-リポキシゲナーゼ/CysLT1シグナルによるがん細胞遊走促進機構解析2014
    • Author(s)
      井本正哉
    • Organizer
      第23回日本がん転移学会学術集会・総会
    • Place of Presentation
      金沢市文化ホール（石川県金沢市）
    • Year and Date
      2014-07-10
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Presentation] 新規アンドロゲン受容体アンタゴニストの探索と薬理活性評価2014
    • Author(s)
      齋藤駿、藤巻貴宏、榊原康文、田代悦、井本正哉
    • Organizer
      日本ケミカルバイオロジー学会第9回年会
    • Place of Presentation
      大阪大学 大阪大学会館（大阪府豊中市）
    • Year and Date
      2014-06-13
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Presentation] 癌の代謝解析による薬剤標的探索2013
    • Author(s)
      井本正哉
    • Organizer
      がんと代謝シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2013-01-08
    • Invited
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Presentation] BiFC法を利用した新規IRE1a活性化阻害剤探索系の構築 Establishment of a new screening system for the inhibitor of IRE1a activation using a BiFC assay2013
    • Author(s)
      田代悦、井本正哉
    • Organizer
      日本がん分子標的治療学会
    • Place of Presentation
      京都国際会議場
    • Year and Date
      2013-06-13
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Presentation] Metabolomic Identification of the Target of Microbial Probes Modulating Cellular Responses2013
    • Author(s)
      Masaya Imoto,
    • Organizer
      , The 2nd International Symposium on Chemical Biology of Natural Products.
    • Place of Presentation
      Yokohama Japan
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-23102001

  • [Presentation] ヒト大腸がん細胞LoVoにおける、EGF誘導体E-cad-herin発現抑制機構の解析2013
    • Author(s)
      大嶽弘之、邊見静香、久田明里、小林大貴、田代悦、井本正哉
    • Organizer
      日本農芸化学会2013年度大会
    • Place of Presentation
      仙台
    • Year and Date
      2013-03-26
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Presentation] Establishment of a New Detection System for the Dimerization of IRE1a Using a BiFC Assay2013
    • Author(s)
      Satoko Shinjo, Etsu Tashiro, Masaya Imoto
    • Organizer
      RIKEN-Max Planck-Join Research Center for 2nd Systems Chemical Biology The Symposium
    • Place of Presentation
      理研(和光)
    • Year and Date
      2013-04-16
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Presentation] BiFC法によるIRE1a二量体化検出法の構築 Establishment of a new detection system for the dimerization of IRE1a by BiFC assay2013
    • Author(s)
      新荘聡子、田代悦、井本正哉
    • Organizer
      日本ケミカルバイオロジー学会
    • Place of Presentation
      東京医科歯科大学
    • Year and Date
      2013-06-20
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Presentation] “Chemistry and biology of Xanthohumol, an inhibitor of Valosin-Containing Protein.”2013
    • Author(s)
      井本正哉
    • Organizer
      EMBO Workshop【AAA+ proteins: from mechanism and disease to targets】
    • Place of Presentation
      Germany・Neuss
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Presentation] The Efficacy and Safety of Mogamulizumab (KW-0761) in Multicenter Phase II Study for Patients with Relapsed Peripheral or Cutaneous T-Cell Lymphoma (abs 041)2013
    • Author(s)
      Ueda R, Ogura M, Ishida T, Hatake K, Taniwaki M, Ando K, Tobinai K, Fujimoto K, Yamamoto K, Miyamoto T, Uike N, Tanimoto M, Tsukasaki K, Ishizawa K, Suzumiya J, Inagaki H, Tamura K, Akinaga S, Tomonaga M.
    • Organizer
      12th International Conference on Malignant Lymphoma.
    • Place of Presentation
      Lugano, Switzerland.
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Presentation] BiFC法によるIRE1a二量体検出法の構築2013
    • Author(s)
      田代悦、新荘聡子、井本正哉
    • Organizer
      日本農芸化学会関東支部2013年度支部大会
    • Place of Presentation
      慶應義塾大学
    • Year and Date
      2013-11-22
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Presentation] UPR誘導剤によるUPR関連遺伝子発現パターンの比較解析 Comparative analysis of the expression patterns of UPR-target genes caused by UPR-inducing compounds2013
    • Author(s)
      田代悦、井本正哉
    • Organizer
      日本癌学会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2013-10-05
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Presentation] Applications of Cryopreserved Mouse Oocytes for In vitro Fertilization Using Fresh， Cold-stored and Frozen Sperm2013
    • Author(s)
      Ishizuka,Y., Yoshimoto,H., Sakoh, K., Nakao, S., Horikoshi, Y., Hirose, Y., Takeuji, S., Sakai, Y., Maeda, Y., Hachiya, M., Mukunoki, A., Takeo, T., Nakagata,N.
    • Organizer
      ANZLAA conference
    • Place of Presentation
      Perth, Australia
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Presentation] 新たなアンドロゲンアンタゴニストの検索のためのアプローチ2012
    • Author(s)
      藤巻貴宏、田代悦、井本正哉
    • Organizer
      第16回日本がん分子標的治療学会
    • Place of Presentation
      小倉
    • Year and Date
      2012-06-29
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Presentation] Senescence-associated secretory phenotypes (SASPs) promote obesity2012
    • Author(s)
      Ohtani, N, Yoshimoto, S, Loo, TM, Kanda, H, Sato, S, Ishikawa, Y, Hara. E.
    • Organizer
      associated hepatocarcinogenesis Keystone symposia
    • Place of Presentation
      Tokyo
    • Year and Date
      2012-10-25
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Presentation] Studies on the Signaling Pathway for Cancer Cell Migration by the Combination of Chemical Biology and Systems Biology2012
    • Author(s)
      Shigeyuki Magi, Etsu Tashiro, and Masaya Imoto
    • Organizer
      FOSBE 2012
    • Place of Presentation
      鶴岡
    • Year and Date
      2012-10-22
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Presentation] Drug Seed Generation from Natural Products2012
    • Author(s)
      Masaya Imoto
    • Organizer
      3rd MEXT-ARDA PROJECT Concluding Joint Seminar and JSPS-NRCT ASIAN CORE PROGRAM Joint Seminar
    • Place of Presentation
      Bangkok（Thailand）
    • Year and Date
      2012-08-26
    • Invited
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Presentation] Xanthohumolのautophagy制御機構解析2012
    • Author(s)
      金墻周平, 他6名、井本正哉
    • Organizer
      日本農芸化学会2012年度大会
    • Place of Presentation
      京都女子大学他(京都)
    • Year and Date
      2012-03-23
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Presentation] A Comparative Analysis of the Expression Patterns of UPR-Target Genes caused by UPR-inducing Compounds2012
    • Author(s)
      Etsu Tashiro, Satoko Shinjo, Yuji Mizotani, and Masaya Imoto
    • Organizer
      EMBO Conference -The Physiology of the ER
    • Place of Presentation
      Girona (Spain)
    • Year and Date
      2012-10-16
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Presentation] 種々の小分子化合物によるUPR関連遺伝子群発現挙動の解析2012
    • Author(s)
      田代悦、新荘聡子、溝谷優治、井本正哉
    • Organizer
      第7回小胞体ストレス研究会
    • Place of Presentation
      広島
    • Year and Date
      2012-11-09
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Presentation] Induction of cellular senescence in obesity2012
    • Author(s)
      Yoshimoto, S, Loo, TM, Kanda, H, Sato, S, Ishikawa, Y, Hara, E, Ohtani, N.
    • Organizer
      associated hepatic carcinogenesis Keystone symposia
    • Place of Presentation
      Dublin, Ireland
    • Year and Date
      2012-05-20
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Presentation] BiFC法によるIRE1二量体化検出法の構築2012
    • Author(s)
      新荘聡子、田代悦、井本正哉
    • Organizer
      日本分子生物学会
    • Place of Presentation
      福岡国際会議場
    • Year and Date
      2012-12-11
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Presentation] XBP1活性化阻害剤の探索と多発性骨髄腫治療薬への応用2012
    • Author(s)
      田代悦、李政樹、岩脇隆夫、飯田真介、井本正哉
    • Organizer
      新学術領域研究「天然物ケミカルバイオロジー:分子標的と活性制御」第2回若手研究者ワークショップ
    • Place of Presentation
      大阪大学中之島センター
    • Year and Date
      2012-10-30
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Presentation] Studies on the Signaling Pathway for Cancer Cell Migration by the Combination of Chemical Biology and Systems Biology2012
    • Author(s)
      Shigeyuki Magi, Etsu Tashiro, and Masaya Imoto
    • Organizer
      FOSBE 2012
    • Place of Presentation
      鶴岡
    • Year and Date
      2012-10-22
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Presentation] CysLT1シグナルはTiam1の発現制御を介してEGF刺激依存的細胞遊走を制御する2012
    • Author(s)
      間木重行、笠松誠人、竹本靖、小林大貴、田代悦、井本正哉
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      札幌
    • Year and Date
      2012-09-20
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Presentation] Quinotrierixin Inhibited Endoplasmic Reticulum Stress-Induced X-box Binding Protein 1 mRNA Splicing through Inhibition of Protein Synthesis2011
    • Author(s)
      Kohta Yamamoto, Etsu Tashiro, and Masaya Imoto
    • Organizer
      5th International Congress on Stress Responses in Biology and Medicine
    • Place of Presentation
      カナダ・ケベック
    • Year and Date
      2011-08-22
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Presentation] Analysis of Machinery for Endoplasmic Reticulum Stress Response Induced by Small Molecular Compounds2011
    • Author(s)
      Satoko Shinjo, Etsu Tashiro, and Masaya Imoto
    • Organizer
      5th International Congress on Stress Responses in Biology and Medicine
    • Place of Presentation
      カナダ・ケベック
    • Year and Date
      2011-08-22
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Presentation] イノスタマイシンによるFGF受容体-1ゴルジ体蓄積機構の解析 Studies on the mechanism of FGF receptor-1 accumulation in golgi apparatus by inostamycin2011
    • Author(s)
      田代悦、張嘉峯、井本正哉
    • Organizer
      日本ケミカルバイオロジー学会
    • Place of Presentation
      東京
    • Year and Date
      2011-05-24
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Presentation] イノスタマイシンによるFGF受容体-1ゴルジ体蓄積機構の解析2011
    • Author(s)
      田代悦、張嘉峯、井本正哉
    • Organizer
      日本ケミカルバイオロジー学会第6回年会
    • Place of Presentation
      東京工業大学(東京)
    • Year and Date
      2011-05-24
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Presentation] 新規MEK1/2阻害剤、SMK-17の抗腫瘍活性2011
    • Author(s)
      木我真基、中山綾子, 他、井本正哉
    • Organizer
      日本ケミカルバイオロジー学会第6回年会
    • Place of Presentation
      東京工業大学(東京)
    • Year and Date
      2011-05-24
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Presentation] 新規アンドロゲンアンタゴニストの探索と薬理活性評価2011
    • Author(s)
      藤巻貴宏、鳥居健太郎, 他、井本正哉
    • Organizer
      日本ケミカルバイオロジー学会第6回年会
    • Place of Presentation
      東京工業大学(東京)
    • Year and Date
      2011-05-25
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Presentation] Metabolomic identification of the target of the filopodia protrusion inhibitor glucopiericidin A2011
    • Author(s)
      Masaya Imoto
    • Organizer
      国際微生物学連合2011会議
    • Place of Presentation
      札幌コンベンションセンター(札幌)(招待講演)
    • Year and Date
      2011-09-07
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Presentation] ケミカルシステムバイオロジーを用いた個別がん細胞の遊走制御機構解析2011
    • Author(s)
      間木重行、田代悦、井本正哉
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-10-04
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Presentation] EGF刺激によるがん細胞遊走におけるCysLT1シグナリングの関与2011
    • Author(s)
      小林大貴、田代悦、井本正哉
    • Organizer
      第15回日本がん分子標的治療学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2011-06-24
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Presentation] CysLT1シグナルにおけるEGF依存的Rac1活性化機構の解析2011
    • Author(s)
      中山諒二, 他3名、井本正哉
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      国立京都国際会館(京都)
    • Year and Date
      2011-09-24
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Presentation] Studies on the signaling pathway for cancer cell migration based on chemical genomic approach2011
    • Author(s)
      Shigeyuki Magi, Etsu Tashiro, Masaya Imoto
    • Organizer
      AACR-NCI-International Conference
    • Place of Presentation
      サンフランシスコ(USA)
    • Year and Date
      2011-11-15
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Presentation] 新規XIAP阻害剤に関する研究2010
    • Author(s)
      松原幸平、河村達郎、田代悦、井本正哉
    • Organizer
      日本癌学会
    • Place of Presentation
      大阪
    • Year and Date
      2010-09-22
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Presentation] UTKO1のがん細胞遊走阻害機構解析2010
    • Author(s)
      小林大貴、田代悦、井本正哉
    • Organizer
      日本がん分子標的治療学会
    • Place of Presentation
      東京
    • Year and Date
      2010-07-07
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Presentation] EGFが誘導するがん細胞遊走における14-3-3 zetaの役割2010
    • Author(s)
      小林大貴、田代悦、井本正哉
    • Organizer
      日本癌学会
    • Place of Presentation
      大阪
    • Year and Date
      2010-09-22
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Presentation] トヨカマイシンは骨髄腫細胞の恒常的なXBP-1活性を阻害して抗腫瘍効果を発揮する2010
    • Author(s)
      李政樹、田代悦、飯田真介、正木彩子、森芙美子、伊藤旭、稲垣淳、楠本茂、石田高司、小松弘和、井本正哉、上田龍三
    • Organizer
      日本血液学会
    • Place of Presentation
      横浜
    • Year and Date
      2010-09-24
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Presentation] ケミカルゲノミクスによる細胞遊走シグナル伝達機構解析2010
    • Author(s)
      間木重行、田代悦、井本正哉
    • Organizer
      日本癌学会
    • Place of Presentation
      大阪
    • Year and Date
      2010-09-22
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Presentation] 微生物由来新規アンドロゲンアンタゴニストHE21の発見2010
    • Author(s)
      藤巻貴宏, 河村達郎, 高橋良和, 五十嵐雅之, 木下直子, 西村吉雄, 田代悦, 井本正哉
    • Organizer
      日本農芸化学会
    • Place of Presentation
      東京
    • Year and Date
      2010-03-29
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Presentation] ケミカルシステムバイオロジーによる遊走制御機構の個別細胞解析2010
    • Author(s)
      間木重行、佐伯雄也、田代悦、井本正哉
    • Organizer
      日本ケミカルバイオロジー学会
    • Place of Presentation
      横浜
    • Year and Date
      2010-05-18
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Presentation] がん悪性化を標的とした制がん剤シードの探索2010
    • Author(s)
      井本正哉
    • Organizer
      日本がん分子標的治療学会
    • Place of Presentation
      東京
    • Year and Date
      2010-07-07
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Presentation] 放線菌由来新規テルペン化合物NT17Aによる細胞死誘導機構の解析2010
    • Author(s)
      小田一成、田代悦、本橋慶一郎、瀬戸治男、井本正哉
    • Organizer
      日本農芸化学会
    • Place of Presentation
      東京
    • Year and Date
      2010-03-29
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Presentation] 微生物由来新規アンドロゲンアンタゴニストHE21の発見2010
    • Author(s)
      藤巻貴宏、河村達郎、高橋良和、五十嵐雅之、木下直子、西村吉雄、田代悦、井本正哉
    • Organizer
      日本ケミカルバイオロジー学会
    • Place of Presentation
      横浜
    • Year and Date
      2010-05-18
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Presentation] ケミカルゲノミクスによる細胞遊走シグナル伝達機構解析2010
    • Author(s)
      間木重行、田代悦、井本正哉
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪
    • Year and Date
      2010-09-24
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Presentation] 微生物由来新規アンドロゲンアンタゴニストHE21の発見2010
    • Author(s)
      藤巻貴宏、河村達郎、高橋良和、五十嵐雅之、木下直子、西村吉雄、田代悦、井本正哉
    • Organizer
      日本農芸化学会2010年度大会
    • Place of Presentation
      東京
    • Year and Date
      2010-03-29
    • Data Source
      KAKENHI-PROJECT-20015043

  • [Presentation] Identification of Trierixin as a novel inhibitor for ER stress-oinduced XBP1 activation from Streptomyces sp.2010
    • Author(s)
      田代悦, 井本正哉
    • Organizer
      アジアコアプログラム第2回合同セミナー
    • Place of Presentation
      タイ・コンケン
    • Year and Date
      2010-11-21
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Presentation] In houseスクリーニングヒット化合物のアンドロゲンアンタゴニスト活性評価2010
    • Author(s)
      鳥居健太郎、小林大貴、藤巻貴宏、河村達郎、田代悦、井本正哉
    • Organizer
      日本ケミカルバイオロジー学会
    • Place of Presentation
      横浜
    • Year and Date
      2010-05-18
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Presentation] アンドロゲンアンタゴニストの薬理活性評価2010
    • Author(s)
      鳥居健太郎、小林大貴、藤巻貴宏、河村達郎、田代悦、井本正哉
    • Organizer
      日本農芸化学会2010年度大会
    • Place of Presentation
      東京
    • Year and Date
      2010-03-29
    • Data Source
      KAKENHI-PROJECT-20015043

  • [Presentation] アンドロゲンアンタゴニストの薬理活性評価2010
    • Author(s)
      鳥居健太郎, 小林大貴, 藤巻貴宏, 河村達郎, 田代悦, 井本正哉
    • Organizer
      日本農芸化学会
    • Place of Presentation
      東京
    • Year and Date
      2010-03-29
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Presentation] ケミカルゲノミクスによるホヤ胚形態形成に関わる分子の探索と機能解析2010
    • Author(s)
      寺井淳、鈴木麻友、日良裕一郎、井本正哉、岡浩太郎、田代悦、堀田耕司
    • Organizer
      日本ケミカルバイオロジー学会
    • Place of Presentation
      横浜
    • Year and Date
      2010-05-18
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Presentation] 微生物由来新規化合物HE21のアンドロゲンアンタゴニスト活性2010
    • Author(s)
      藤巻貴宏、鳥井健太郎、河村達郎、小林大貴、田代悦、井本正哉
    • Organizer
      日本がん分子標的治療学会
    • Place of Presentation
      東京
    • Year and Date
      2010-07-07
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Presentation] ケミカルシステムバイオロジーによる遊走制御機構の個別細胞解析2010
    • Author(s)
      間木重行、井本正哉, 他2名
    • Organizer
      日本ケミカルバイオロジー学会第5回年会
    • Place of Presentation
      慶應義塾大学(神奈川県)
    • Year and Date
      2010-05-19
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Presentation] 新規XBP1活性化阻害剤キノトリエリキシンは不良タンパク質の蓄積を阻害することで小胞体ストレスを抑制する2009
    • Author(s)
      山本浩太、田代悦、井本正哉
    • Organizer
      日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2009-10-01
    • Data Source
      KAKENHI-PROJECT-20015043

  • [Presentation] アポトーシス抑制タンパク質XIAPの阻害物質の探索2009
    • Author(s)
      河村達郎、大高瞳、田代悦、井本正哉
    • Organizer
      がん分子標的治療学会
    • Place of Presentation
      徳島
    • Year and Date
      2009-06-26
    • Data Source
      KAKENHI-PROJECT-20015043

  • [Presentation] キノトリエリキシンによるXBP1活性化阻害機構の解析2009
    • Author(s)
      山本浩太, 田代悦, 河村達郎, 井本正哉
    • Organizer
      日本ケミカルバイオロジー学会
    • Place of Presentation
      神戸
    • Year and Date
      2009-05-18
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Presentation] BrefeldinAが誘導する小胞体ストレス応答の制御機構解析2009
    • Author(s)
      新荘聡子、田代悦、井本正哉
    • Organizer
      日本農芸化学会
    • Place of Presentation
      福岡
    • Year and Date
      2009-03-27
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Presentation] Generation of "Natural Unnatural Product Library" and identification of small molecule XIAP inhibitors2009
    • Author(s)
      Kawamura T, Otaka H, Tashiro E, Imoto M.
    • Organizer
      2009 AACR-NCI-EORTC Molecular Targets and Cancer Therapeutics conference
    • Place of Presentation
      Boston, USA
    • Year and Date
      2009-11-16
    • Data Source
      KAKENHI-PROJECT-17012025

  • [Presentation] in sihcoスクリーンを用いたアンドロゲンアンタゴニストの探索2009
    • Author(s)
      鳥居健太郎、小林大貴、長嶺誠香、田代悦、榊原康文、井本正哉
    • Organizer
      第28回メディシナルケミストリーシンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2009-11-26
    • Data Source
      KAKENHI-PROJECT-20015043

  • [Presentation] Toyocamycin inhibits ER stress-induced XBP1 mRNA splicing through IRE1a inhibition2009
    • Author(s)
      Etsu Tashiro, Yumi Yokouchi, Kohta Yamamoto, Masaya Imoto
    • Organizer
      AACR-NCI-EORTC合同国際カンファレンス
    • Place of Presentation
      ボストン(米国)
    • Year and Date
      2009-11-16
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Presentation] in silico スクリーニングによるアンドロゲンアンタゴニストの探索2009
    • Author(s)
      鳥居健太郎, 小林大貴, 長嶺誠香, 田代悦, 榊原康文, 井本正哉
    • Organizer
      日本ケミカルバイオロジー学会
    • Place of Presentation
      神戸
    • Year and Date
      2009-05-18
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Presentation] アポトーシス抑制タンパク質XLAPの阻害物質の探索2009
    • Author(s)
      河村達郎、大高瞳、田代悦、井本正哉
    • Organizer
      第13回がん分子標的治療学会学術集会
    • Place of Presentation
      徳島
    • Year and Date
      2009-06-26
    • Data Source
      KAKENHI-PROJECT-17012025

  • [Presentation] がん細胞の遊走におけるCysLT1シグナリングの関与2009
    • Author(s)
      田中理子, 竹本靖, 田代悦, 井本正哉
    • Organizer
      がん分子標的治療学会
    • Place of Presentation
      徳島
    • Year and Date
      2009-06-25
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Presentation] 新規XBP1阻害剤キノトリエリキシンは不良タンパク質の蓄積を阻害することで小胞体ストレスを抑制する2009
    • Author(s)
      山本浩太, 田代悦, 井本正哉
    • Organizer
      日本癌学会
    • Place of Presentation
      横浜
    • Year and Date
      2009-10-03
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Presentation] メタボローム解析による GlucopiericidinA の標的分子解析2009
    • Author(s)
      北川光洋, 田代悦, 曽我朋義, 井本正哉
    • Organizer
      日本ケミカルバイオロジー学会
    • Place of Presentation
      神戸
    • Year and Date
      2009-05-18
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Presentation] Generation of "Natural Unnatural Product Library" and identification of small molecule XIAP inhibitors2009
    • Author(s)
      Tatsuro Kawamura, Hitomi Otaka, Etsu Tashiro, Masaya Imoto
    • Organizer
      AACR-NCI-EORTC合同国際カンファレンス
    • Place of Presentation
      ボストン(米国)
    • Year and Date
      2009-11-16
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Presentation] UTKO1によるがん細胞遊走阻害機構の解析2009
    • Author(s)
      小林大貴, 高野圭, 澤田雅人, 田代悦, 井本正哉
    • Organizer
      日本癌学会
    • Place of Presentation
      横浜
    • Year and Date
      2009-10-02
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Presentation] Toyocamycin inhibits ER stress-induced XBP1 mRNA splicing through IRE1a inhibition2009
    • Author(s)
      Etsu Tashiro, Yumi Yokouchi, Kohta Yamamoto, Masaya Imoto
    • Organizer
      AACR-EORTC-NCI合同カンファレンス「Molecular Targets and Cancer Therapeutics」
    • Place of Presentation
      米国・ボストン
    • Year and Date
      2009-11-16
    • Data Source
      KAKENHI-PROJECT-20015043

  • [Presentation] ケミカルシステムバイオロジーによる細胞遊走シグナル伝達機構の解析2009
    • Author(s)
      間木重行, 田代悦, 井本正哉
    • Organizer
      日本ケミカルバイオロジー学会
    • Place of Presentation
      神戸
    • Year and Date
      2009-05-18
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Presentation] Generation of "Natural Unnatural Product Library" and indentification of small molecule XIAP inhibitors2009
    • Author(s)
      Tatsuro Kawamura, Hitomi Otka, Etsu Tashiro, Masaya Imoto
    • Organizer
      AACR-EORTC-NCI合同カンファレンス「Molecular Targets and Cancer Therapeutics」
    • Place of Presentation
      米国・ボストン
    • Year and Date
      2009-11-16
    • Data Source
      KAKENHI-PROJECT-20015043

  • [Presentation] アポトーシス抑制タンパク質XIAPの阻害物質の探索2009
    • Author(s)
      河村達郎, 大高瞳, 田代悦, 井本正哉
    • Organizer
      がん分子標的治療学会
    • Place of Presentation
      徳島
    • Year and Date
      2009-06-25
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Presentation] キノトリエリキシンによるXBP1活性化阻害機構の解析2009
    • Author(s)
      山本浩太、田代悦、河村達郎、井本正哉
    • Organizer
      日本ケミカルバイオロジー学会第4回年会
    • Place of Presentation
      神戸
    • Year and Date
      2009-05-18
    • Data Source
      KAKENHI-PROJECT-20015043

  • [Presentation] in silicoスクリーンによるアンドロゲンアンタゴニストの探索2009
    • Author(s)
      鳥居健太郎、小林大貴、長嶺誠香、田代悦、榊原康文、井本正哉
    • Organizer
      第4回ケミカルバイオロジー学会
    • Place of Presentation
      神戸
    • Year and Date
      2009-05-18
    • Data Source
      KAKENHI-PROJECT-20015043

  • [Presentation] ケミカルゲノミクスによる細胞遊走シグナル伝達機構解析2009
    • Author(s)
      間木重行, 田代悦, 井本正哉
    • Organizer
      日本分子生物学会
    • Place of Presentation
      横浜
    • Year and Date
      2009-12-10
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Presentation] UTKO1によるがん細胞遊走阻害機構の解析2009
    • Author(s)
      高野圭, 小林大貴, 小倉由資, 澤田雅人, 久保伸一郎, 田代悦, 渡邉秀典, 井本正哉
    • Organizer
      日本分子生物学会
    • Place of Presentation
      横浜
    • Year and Date
      2009-12-12
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Presentation] 新規XBP1阻害剤キノトリエリキシンは不良タンパク質の蓄積を阻害することで小胞体ストレスを抑制する2009
    • Author(s)
      山本浩太、田代悦、井本正哉
    • Organizer
      ケミカルバイオロジー学会
    • Place of Presentation
      神戸
    • Year and Date
      2009-05-18
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Presentation] Toyocamycin inhibits ER stress-induced XBP1 mRNA splicing through IRE1a inhibition2009
    • Author(s)
      Etsu Tashiro, Yumi Yokouchi, 山本浩太, 井本正哉
    • Organizer
      AACR-NCI-EORTC合同国際カンファレンス
    • Place of Presentation
      ボストン
    • Year and Date
      2009-11-16
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Presentation] トリエリキシンおよびその類縁体のXBP1阻害活性および抗腫瘍活性の評価2008
    • Author(s)
      河村達郎、田代悦、井本正哉
    • Organizer
      がん分子標的治療研究会
    • Place of Presentation
      東京
    • Year and Date
      2008-06-26
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Presentation] メタボローム解析を用いたケミカルバイオロジー2008
    • Author(s)
      井本正哉
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-11
    • Data Source
      KAKENHI-PROJECT-19310146

  • [Presentation] 小胞体ストレスが誘導する転写因子XBP1の活性化を抑制する新規化合物トリエリキシンとキノトリエリキシンの発見・構造解析・生物活性・構造活性相関2008
    • Author(s)
      河村達郎、田代悦、二村友史、新藤一敏、井本正哉
    • Organizer
      天然有機化合物討論会
    • Place of Presentation
      福岡
    • Year and Date
      2008-09-30
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Presentation] 小胞体ストレスが誘導する転写因子XBP1の活性化を抑制する新規化合物トリエリキシンとキノトリエリキシンの発見・ 構造解析・ 生物活性・ 構造活性相関2008
    • Author(s)
      河村達郎, 田代悦, 二村友史新藤一敏, 井本正哉
    • Organizer
      天然有機化合物討論会
    • Place of Presentation
      福岡
    • Year and Date
      2008-09-30
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Presentation] V-ATPase阻害剤によるBcl-xL抗アポトーシス作用の克服2008
    • Author(s)
      笹澤有紀子, 二村友史, 田代悦, 井本正哉
    • Organizer
      第12回がん分子標的治療研究会総会
    • Place of Presentation
      東京
    • Year and Date
      2008-06-27
    • Data Source
      KAKENHI-PROJECT-17012025

  • [Presentation] 小分子化合物と統計処理を用いた小胞体ストレス応答機構の解析2008
    • Author(s)
      新庄聡子、田代悦、井本正哉
    • Organizer
      日本ケミカルバイオロジー研究会
    • Place of Presentation
      東京
    • Year and Date
      2008-05-19
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Presentation] トヨカマイシンによるXBP1活性化阻害機構の解析2008
    • Author(s)
      田代悦, 井本正哉
    • Organizer
      ケミカルバイオロジー研究会
    • Place of Presentation
      東京
    • Year and Date
      2008-05-19
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Presentation] メタボローム解析を用いたケミカルバイオロジー2008
    • Author(s)
      井本正哉
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-11
    • Data Source
      KAKENHI-PROJECT-20015043

  • [Presentation] 新規XBP1活性化阻害剤トリエリキシンの発見2008
    • Author(s)
      田代悦、二村友史、井本正哉
    • Organizer
      日本癌学会
    • Place of Presentation
      横浜
    • Year and Date
      2008-10-28
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Presentation] ナフトキノン化合物JJを用いたCyclin Dl発現量低下機構の解析2008
    • Author(s)
      岡田良子, 田代悦, 斉藤毅, 西山繁, 井本正我
    • Organizer
      第12回がん分子標的治療研究会総会
    • Place of Presentation
      東京
    • Year and Date
      2008-06-27
    • Data Source
      KAKENHI-PROJECT-17012025

  • [Presentation] トヨカマイシンによるXBP1活性化阻害機構の解析2008
    • Author(s)
      田代悦、井本正哉
    • Organizer
      日本ケミカルバイオロジー研究会
    • Place of Presentation
      東京
    • Year and Date
      2008-05-19
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Presentation] Identification of trierixin as a novel inhibitor for ER stress-induced XBP1 activation from Streptomyces sp.2008
    • Author(s)
      田代悦, 二村友史, 井本正哉
    • Organizer
      日本癌学会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-10-28
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Presentation] トヨカマイシンによるXBP1 活性化阻害機構の解析2008
    • Author(s)
      田代悦、井本正哉
    • Organizer
      がん分子標的治療研究会
    • Place of Presentation
      東京
    • Year and Date
      2008-06-26
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Presentation] アンドロゲン受容体を標的とした抗がんペプチド薬の開発2007
    • Author(s)
      井本正哉, 小野賢, 田代悦
    • Organizer
      第11回がん分子標的治療研究会総会
    • Place of Presentation
      大阪
    • Year and Date
      2007-07-05
    • Data Source
      KAKENHI-PROJECT-17012025

  • [Presentation] メチルゲルフェリンはGLO1阻害を介して破骨細胞の分化を阻害する2007
    • Author(s)
      川谷誠, 奥村英夫, 井本正哉, 長田裕之.
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会大会合同大会 BMB2007
    • Place of Presentation
      横浜
    • Year and Date
      2007-12-11
    • Data Source
      KAKENHI-PROJECT-17012025

  • [Presentation] Inhibition of tumor cell migration by BU-4664L2007
    • Author(s)
      Yasushi Takemoto, Etsu Tashiro and Masaya Imoto
    • Organizer
      日本癌学会
    • Place of Presentation
      横浜
    • Year and Date
      2007-10-03
    • Data Source
      KAKENHI-PROJECT-19310146

  • [Presentation] イノスタマイシンによるTRAIL感受性増強機構の解析2007
    • Author(s)
      田代悦, 牧野雅史, 井本正哉
    • Organizer
      第11回がん分子標的治療研究会総会
    • Place of Presentation
      大阪
    • Year and Date
      2007-07-05
    • Data Source
      KAKENHI-PROJECT-17012025

  • [Presentation] 癌の代謝解析による薬剤標的探索
    • Author(s)
      井本正哉
    • Organizer
      がんと代謝シンポジウム
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Presentation] BiFC法によるIRE1α二量体化検出法の構築
    • Author(s)
      新荘聡子、田代悦、井本正哉
    • Organizer
      日本ケミカルバイオロジー学会
    • Place of Presentation
      東京医科歯科大学
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Presentation] Chemistry and biology of Xanthohumol, an inhibitor of Valosin-Containing Protein.
    • Author(s)
      井本正哉
    • Organizer
      EMBO Workshop【AAA+ proteins: from mechanism and disease to targets】
    • Place of Presentation
      Neuss, Germany
    • Invited
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Presentation] Drug Seed Generation from Natural Products
    • Author(s)
      Masaya Imoto
    • Organizer
      3rd MEXT-ARDA PROJECT Concluding Joint Seminar and JSPS-NRCT ASIAN CORE PROGRAM Joint Seminar
    • Place of Presentation
      Bangkok（Thailand）
    • Invited
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Presentation] 天然化合物を用いたケミカルバイオロジー研究
    • Author(s)
      井本正哉
    • Organizer
      日本薬学会第134年会シンポジウム
    • Place of Presentation
      熊本
    • Invited
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Presentation] 新たなアンドロゲンアンタゴニストの検索のためのアプローチ
    • Author(s)
      藤巻貴宏、田代悦、井本正哉
    • Organizer
      第16回日本がん分子標的治療学会
    • Place of Presentation
      小倉
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Presentation] CysLT1シグナルはTiam1の発現制御を介してEGF刺激依存的細胞遊走を制御する
    • Author(s)
      間木重行、笠松誠人、竹本靖、小林大貴、田代悦、井本正哉
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      札幌
    • Invited
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Presentation] Optical Molecular Imaging and Assessment of Therapeutic Response of Colorectal Cancer Targeting Epidermal Growth Factor Receptor
    • Author(s)
      Muguruma N, Miyamoto Y, Fujimoto S, Fujino Y, Okada Y, Kitamura S, Kimura T, Okamoto K, Miyamoto H, Takayama T.
    • Organizer
      The world Molecular Imaging Congress
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2014-09-17 – 2014-09-20
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Presentation] 天然化合物を用いたケミカルバイオロジー研究
    • Author(s)
      井本正哉
    • Organizer
      日本薬学会第134年会シンポジウム
    • Place of Presentation
      熊本
    • Invited
    • Data Source
      KAKENHI-PROJECT-25560419

  • [Presentation] Cold transport of mouse epididymides for distributing and archiving genetically engineered mice
    • Author(s)
      Takeo, T., Yoshimoto, H., Nakao, S., Ishizuka, Y., Horikoshi, Y., Takeuji, S., Hirose, Y., Mukunoki, A., Fukumoto, K., Kondo, T., Haruguchi, Y., Takeshita, Y., Nakamuta, Y., Tsuchiyama, S., Takahashi, F., Iwamoto, M., Shimizu, N., Li, M., Lloyd, K. and Nakagata, N.
    • Organizer
      第8回次世代を担う若手医療薬科学シンポジウム
    • Place of Presentation
      熊本大学薬学部(熊本県・熊本市)
    • Year and Date
      2014-11-15 – 2014-11-16
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Presentation] オートファジーに挑むケミカルバイオロジー
    • Author(s)
      井本正哉
    • Organizer
      新規素材探索研究会 第12回セミナー
    • Place of Presentation
      横浜
    • Invited
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Presentation] UPR誘導剤によるUPR関連遺伝子発現パターンの比較解析
    • Author(s)
      田代悦、井本正哉
    • Organizer
      日本癌学会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Presentation] BiFC法を利用した新規IRE1α活性化阻害剤探索系の構築
    • Author(s)
      田代悦、井本正哉
    • Organizer
      日本がん分子標的治療学会
    • Place of Presentation
      京都国際会議場
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Presentation] Application of cold-storage of mouse sperm for shipping genetically engineered mice
    • Author(s)
      Takeuji, S., Yoshimoto, H., Nakao, S., Horikoshi, Y., Hirose, Y., Mukunoki, A., Shirakado, K., Takemoto, K., Takeo, T. and Nakagata, N.
    • Organizer
      第8回次世代を担う若手医療薬科学シンポジウム
    • Place of Presentation
      熊本大学薬学部(熊本県・熊本市)
    • Year and Date
      2014-11-15 – 2014-11-16
    • Invited
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Presentation] ホップ成分キサントフモールのオートファジー制御機構と抗がん活性評価
    • Author(s)
      井本正哉
    • Organizer
      第5回食品薬学シンポジウム
    • Place of Presentation
      京都
    • Invited
    • Data Source
      KAKENHI-PROJECT-25560419

  • [Presentation] オートファジーに挑むケミカルバイオロジー
    • Author(s)
      井本正哉
    • Organizer
      新規素材探索研究会 第12回セミナー
    • Place of Presentation
      横浜
    • Invited
    • Data Source
      KAKENHI-PROJECT-25560419

  • [Presentation] Chemistry and biology of Xanthohumol, an inhibitor of Valosin-Containing Protein.
    • Author(s)
      井本正哉
    • Organizer
      EMBO Workshop【AAA+ proteins: from mechanism and disease to targets】
    • Place of Presentation
      Neuss, Germany
    • Invited
    • Data Source
      KAKENHI-PROJECT-25560419

  • [Presentation] オートファジー制御機構の網羅的解析に向けた評価系の構築
    • Author(s)
      加藤直裕、間木重行、田代悦、井本正哉
    • Organizer
      第35回日本分子生物学会年会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Presentation] 日本における天然物創薬の現状
    • Author(s)
      井本正哉
    • Organizer
      日本農芸化学会2014年度大会シンポジウム
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Presentation] Comparative Analysis of the Expression Patterns of UPR-Target Genes Caused by UPR-Inducing Compounds
    • Author(s)
      Etsu Tashiro, Satoko Shinjo, Yuji Mizotani, and Masaya Imoto
    • Organizer
      RIKEN-Max Planck Joint Research Center for Systems Chemical Biology 3rd Annual Symposium
    • Place of Presentation
      ドイツ・Schloss Ringberg
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Presentation] 小分子化合物が誘導するUPR関連遺伝子発現挙動の解析
    • Author(s)
      新荘聡子、溝谷優治、田代悦、井本正哉
    • Organizer
      日本ケミカルバイオロジー学会
    • Place of Presentation
      京都大学
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Presentation] Drug Seed Generation from Natural Products
    • Author(s)
      Masaya Imoto
    • Organizer
      3rd MEXT-ARDA PROJECT Concluding Joint Seminar and JSPS-NRCT ASIAN CORE PROGRAM Joint Seminar
    • Place of Presentation
      Bangkok・Thailand
    • Invited
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Presentation] ホップ成分キサントフモールのオートファジー制御機構と抗がん活性評価
    • Author(s)
      井本正哉
    • Organizer
      第5回食品薬学シンポジウム
    • Place of Presentation
      京都
    • Invited
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Presentation] 日本における天然物創薬の現状
    • Author(s)
      井本正哉
    • Organizer
      日本農芸化学会2014年度大会シンポジウム
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-25560419

  • [Presentation] A Comparative Analysis of the Expression Patterns of UPR-Target Genes caused by UPR-inducing Compounds
    • Author(s)
      Etsu Tashiro, Satoko Shinjo, Yuji Mizotani, and Masaya Imoto
    • Organizer
      EMBO Conference - The Physiology of the ER
    • Place of Presentation
      Girona (Spain)
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Presentation] イノスタマイシンによる細胞膜表面DR5の発現上昇を介したTRAIL誘導性アポトーシス増強
    • Author(s)
      田代悦、山本浩太、井本正哉
    • Organizer
      日本ケミカルバイオロジー学会
    • Place of Presentation
      京都大学
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Presentation] Establishment of a New Detection System for the Dimerization of IRE1a Using a BiFC Assay
    • Author(s)
      Satoko Shinjo, Etsu Tashiro, Masaya Imoto
    • Organizer
      RIKEN-Max Planck-Join Research Center for Systems Chemical Biology The 2nd Symposium
    • Place of Presentation
      理研（和光）
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Presentation] Studies on the Signaling Pathway for Cancer Cell Migration by the Combination of Chemical Biology and Systems Biology
    • Author(s)
      Shigeyuki Magi, Etsu Tashiro, and Masaya Imoto
    • Organizer
      FOSBE 2012
    • Place of Presentation
      鶴岡
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Presentation] XBP1活性化阻害剤の探索と多発性骨髄腫治療薬への応用
    • Author(s)
      田代悦、李政樹、岩脇隆夫、飯田真介、井本正哉
    • Organizer
      新学術領域研究「天然物ケミカルバイオロジー：分子標的と活性制御」　第2回若手研究者ワークショップ
    • Place of Presentation
      大阪大学中之島センター
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Presentation] BiFC法によるIRE1α二量体検出法の構築
    • Author(s)
      田代悦、新荘聡子、井本正哉
    • Organizer
      日本農芸化学会関東支部2013年度支部大会
    • Place of Presentation
      慶應義塾大学
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Presentation] Establishment of a New Detection System for the Dimerization of IRE1α Using a BiFC Assay
    • Author(s)
      Etsu Tashiro, Satoko Shinjo, Masaya Imoto
    • Organizer
      The 7th Japan-Korea Chemical Biology Symposium
    • Place of Presentation
      韓国・チェジュ島
    • Data Source
      KAKENHI-PROJECT-23510283
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  • 70.  KITA Yoshikuni (30147524)
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    # of Collaborated Products : 8results
  • 71.  KURIKI Kiyonori (20543705)
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    # of Collaborated Products : 0results
  • 72.  TAMAKAOSHI Akiko (90236737)
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    # of Collaborated Products : 0results
  • 73.  EGUCHI Hidetaka (00260232)
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    # of Collaborated Products : 3results
  • 74.  KUBO Michiaki (30442958)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 1results
  • 75.  HAMAJIMA Nobuyuki (30172969)
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    # of Collaborated Products : 5results
  • 76.  NAGATA Chisato (30283295)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 2results
  • 77.  HINO Okio (90127910)
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    # of Collaborated Products : 2results
  • 78.  SUGIMURA Haruhiko (00196742)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 1results
  • 79.  TSUGANE Shoichiro (40179982)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 80.  NAKATOCHI Masahiro (10559983)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 1results
  • 81.  TAKAYAMA Tetsuji (10284994)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 2results
  • 82.  AKAZA Hideyuki (70010486)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 1results
  • 83.  TAKAHASHI Satoru (50197141)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 7results
  • 84.  TSUKAMOTO Taiji (50112454)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 85.  NAITO Seiji (40164107)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 4results
  • 86.  MASUMORI Naoya (20295356)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 87.  YOKOMIZO Akira (60346781)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 88.  NAMIKI Mikio (70155985)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 1results
  • 89.  FUJIMOTO Kiyohide (50264867)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 14results
  • 90.  FUJIOKA Tomoaki (80173409)
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    # of Collaborated Products : 0results
  • 91.  HORIE Shigeo (40190243)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 1results
  • 92.  MORI Mitsuru (50175634)
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    # of Collaborated Products : 12results
  • 93.  MORIWAKI Hisataka (50174470)
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    # of Collaborated Products : 0results
  • 94.  Shimizu Masahito (90402198)
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    # of Collaborated Products : 4results
  • 95.  KANNAGI Mari (80202034)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 96.  ISHIDA Takashi (80405183)
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    # of Collaborated Products : 5results
  • 97.  MATSUOKA Masao (10244138)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 98.  YAMAOKA Shoji (90263160)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 1results
  • 99.  TANAKA Yuetsu (30163588)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 11results
  • 100.  WATANABE Toshiki (30182934)
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    # of Collaborated Products : 3results
  • 101.  YASUI Hiroshi (40448593)
    # of Collaborated Projects : 1results
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  • 102.  TSUCHIYA Eiju (00072314)
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    # of Collaborated Products : 3results
  • 103.  DAIGO Yataro (30345029)
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    # of Collaborated Products : 0results
  • 104.  MIYAGI Yohei (00254194)
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    # of Collaborated Products : 1results
  • 105.  TAKAHASHI Takashi (50231395)
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  • 106.  TOMIDA Akihiro (40251483)
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    # of Collaborated Products : 2results
  • 107.  MASHIMA Tetsuo (30311228)
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    # of Collaborated Products : 2results
  • 108.  TOKINO Takashi (40202197)
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    # of Collaborated Products : 0results
  • 109.  SUZUKI Hiromu (20381254)
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    # of Collaborated Products : 5results
  • 110.  SHINOMURA Yasuhisa (90162619)
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    # of Collaborated Products : 1results
  • 111.  NOSHO Katsuhiko (10597339)
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    # of Collaborated Products : 0results
  • 112.  MIYAZONO Kohei (90209908)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 113.  INAZAWA Johji (30193551)
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    # of Collaborated Products : 0results
  • 114.  HIROTA Toru (50421368)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 115.  NODA Tetsuo (10183550)
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    # of Collaborated Products : 0results
  • 116.  SUZUKI Misao (60253720)
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    # of Collaborated Products : 5results
  • 117.  TAKEDA Naoki (90304998)
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    # of Collaborated Products : 0results
  • 118.  YAGINUMA Katsuyuki (40182307)
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    # of Collaborated Products : 0results
  • 119.  SUGITANI Yoshinobu (80360569)
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    # of Collaborated Products : 0results
  • 120.  ITO Hidemi (90393123)
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  • 121.  HOSONO Satoyo (80402600)
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    # of Collaborated Products : 1results
  • 122.  IWASAKI Motoki (60392338)
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    # of Collaborated Products : 0results
  • 123.  NAGASE Hiroki (90322073)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 124.  NISHITA Hiroki (40531257)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 125.  KONO Suminori (70128015)
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    # of Collaborated Products : 0results
  • 126.  HASHIMOTO Syuji (50148334)
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    # of Collaborated Products : 7results
  • 127.  YAMAGUCHI Kazunari (20128325)
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    # of Collaborated Products : 1results
  • 128.  TAKANO Atsushi (50582607)
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    # of Collaborated Products : 2results
  • 129.  TERAMOTO Koji (10452244)
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  • 130.  MATSUDA Koichi (90401257)
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  • 131.  TANAKA Yukichi (50420691)
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  • 132.  AOKI Ichiro (00184028)
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  • 133.  OSAMURA Yoshiyuki (10100992)
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  • 134.  NAKAMURA Naoya (50227922)
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    # of Collaborated Products : 1results
  • 135.  SUZUKI Noboru (40235982)
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    # of Collaborated Products : 5results
  • 136.  TAJIRI Michihiko (00449117)
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  • 137.  KAWASAKI Takashi (20377188)
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    # of Collaborated Products : 0results
  • 138.  YOKOSE Tomoyuki (10221665)
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  • 139.  YANAGISAWA Kiyoshi (20372112)
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    # of Collaborated Products : 1results
  • 140.  HIRAKAWA Akihiro (90609330)
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  • 141.  IIJIMA Yoshihiko (50584679)
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    # of Collaborated Products : 1results
  • 142.  ZEMBUTSU Hitoshi (90372820)
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  • 143.  SASAKI Yasushi (70322328)
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    # of Collaborated Products : 1results
  • 144.  IDOGAWA Masashi (00404749)
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  • 145.  MARUYAMA Reo (60607985)
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    # of Collaborated Products : 0results
  • 146.  KAI Masahiro (80260777)
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  • 147.  UEDA Minoru (60265931)
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    # of Collaborated Products : 1results
  • 148.  HOTTA Kouji (80407147)
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    # of Collaborated Products : 1results
  • 149.  OKA Koutaro (10276412)
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    # of Collaborated Products : 1results
  • 150.  OTSUKA Masami (40126008)
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    # of Collaborated Products : 0results
  • 151.  OKAMOTO Yoshinari (20194409)
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    # of Collaborated Products : 0results
  • 152.  YAMASAKI Tetsuo (60182474)
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    # of Collaborated Products : 0results
  • 153.  OKAWARA Tadashi (60040325)
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    # of Collaborated Products : 0results
  • 154.  UMEZAWA Kazuo (70114402)
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    # of Collaborated Products : 0results
  • 155.  SATO Kengo (20365472)
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    # of Collaborated Products : 0results
  • 156.  YUGI Katsuyuki (70433745)
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    # of Collaborated Products : 0results
  • 157.  MUROI Makoto (30261168)
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    # of Collaborated Products : 0results
  • 158.  FUNAYAMA Manabu (70468578)
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    # of Collaborated Products : 0results
  • 159.  YAMADA Daisuke (30757539)
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    # of Collaborated Products : 0results
  • 160.  桑野 信彦 (80037431)
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    # of Collaborated Products : 0results
  • 161.  岡田 信子 (70194346)
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    # of Collaborated Products : 0results
  • 162.  小河原 宏 (00097198)
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    # of Collaborated Products : 0results
  • 163.  岡部 實裕 (40113534)
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    # of Collaborated Products : 0results
  • 164.  野瀬 清 (70012747)
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  • 165.  内藤 幹彦 (00198011)
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  • 166.  谷下 一夫 (10101776)
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  • 167.  池田 満里子 (00051368)
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  • 168.  三高 俊宏 (50231618)
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    # of Collaborated Products : 0results
  • 169.  中村 祐輔 (70217909)
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    # of Collaborated Products : 1results
  • 170.  入江 一浩 (00168535)
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    # of Collaborated Products : 1results
  • 171.  渡邉 秀典 (00202416)
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    # of Collaborated Products : 1results
  • 172.  品田 哲郎 (30271513)
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  • 173.  小林 資正 (40116033)
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    # of Collaborated Products : 1results
  • 174.  叶 直樹 (40317293)
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  • 175.  岡本 隆一 (50451935)
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    # of Collaborated Products : 0results
  • 176.  松永 茂樹 (60183951)
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  • 177.  半田 宏&