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IMOTO Masaya  井本 正哉

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… Alternative Names

井本 正哉  イモト マサヤ

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Researcher Number 60213253
Other IDs
Affiliation (Current) 2022: 順天堂大学, 大学院医学研究科, 特任教授
Affiliation (based on the past Project Information) *help 2022: 順天堂大学, 大学院医学研究科, 特任教授
2020 – 2021: 順天堂大学, 医学(系)研究科(研究院), 特任教授
2015 – 2020: 慶應義塾大学, 理工学部(矢上), 教授
2002 – 2018: 慶應義塾大学, 理工学部, 教授
2013: 慶應義塾大学, 理工学部(矢上), 教授 … More
1999 – 2001: 慶應義塾大学, 理工学部, 助教授
1999 – 2000: 慶応義塾大学, 理工学部, 助教授
1998: 慶応大学, 理工学部, 助教授
1997: 慶応義塾大学, 理工学部, 助教授
1996: 慶應義塾大学, 理工学部, 助教授
1995: 慶応義塾大学, 理工学部, 助教授
1992 – 1993: 慶應義塾大学, 理工学部, 講師 Less
Review Section/Research Field
Principal Investigator
Living organism molecular science / Biological Sciences / Basic Section 37020:Chemistry and chemical methodology of biomolecules-related / Bioinformatics/Life informatics / Science and Engineering / Chemical biology / Biomolecular chemistry
Except Principal Investigator
Biological Sciences / Neurology / Science and Engineering … More / Medium-sized Section 52:General internal medicine and related fields / Basic Section 52020:Neurology-related / Biomedical engineering/Biological material science / Chemical biology / Chemical biology / 医薬分子機能学 / Bioinformatics/Life informatics / Biomolecular chemistry / Chemical biology Less
Keywords
Principal Investigator
アポトーシス / オートファジー / 細胞遊走 / パーキンソン病 / ケミカルバイオロジー / がん / V-ATPase / イノスタマイシン / がん細胞 / レプトマイシン … More / 遺伝子 / 癌 / シグナル伝達 / 5-リポキシゲナーゼ / CysLT1 / 前立腺がん / パーキンソン疾患 / パーキンソン症 / パーキンソン / 神経変性疾患 / 相分離 / アグリソーム / EGF受容体 / pRB / アンギノマイシンB / セラミド / PKC / 異常増殖 / Bcl-2 / PDGF受容体 / サイクリンD1 / CDC25A / 低分子量Gタンパク質 / 浸潤 / ゲラニルゲラニル基合成酵素 / 酵素阻害剤 / 微生物二次代謝産物 / ゲルフェリン / イノシトールリン脂質代謝回転 / ceramide合成 / BH1ドメイン / Bax / ドミナントネガティブ / FGF receptor / プロモーター / E2F-1 / 癌悪性化 / 転移 / 細胞運動 / マイグラスタチン / ムベラスチン / 天然化合物 / 核外移行シグナル / 2次元電気泳動 / ペプチドマスフィンガープリント / HeLa細胞 / アルゴリズム / コンセンサス配列 / プロテオーム / 隠れマルコフモデル / 遺伝的アルゴリズム / プロファイル / ロイコトリエンC_4 / 遊走 / ラメリポディア / Rac1 / UTKO-1 / ビオチン標識 / Rac / フィロポディア / ピエリシジン / EGF / アンドロゲン受容体 / CysLT1アンタゴニスト / がん転移 / α-synuclein / システム生物学 / パスウェイ解析 / パスウエイ解析 / リポキシゲナーゼ / アンドロゲンアンタゴニスト / βカテニン / アンタルライド / キサントフモール / ノナクチン / 難治疾患 / 天然物リガンド / 作用解析機構 / VCP / EMT / 放線菌培養液 / 神経細胞 / MPP / ホヤ / 脊索管形成 / 化学発生学 / 14-3-3 / UTKO1 / メタボローム 解析 / タンパク質凝集 / ビリルビン / 凝集タンパク質 / バイオマーカー / ユビキリン / αシヌクレイン … More
Except Principal Investigator
オートファジー / パーキンソン病 / ケミカルバイオロジー / 血管新生 / 転移 / 神経内科学 / 制癌物質 / 癌抑制遺伝子 / 情報伝達系 / 血小板産生 / がん遺伝子 / シグナル伝達 / がん抑制遺伝子 / スクリーニング / 小胞体ストレス / 標的同定 / 天然物化学 / 小分子化合物 / リソソーム / 内科 / 脳・神経 / 神経変性疾患 / 活性化酸素 / 細胞外マトリックス / 制がん物質 / IL-6 / 薬剤耐性 / 制がん剤 / 足場非依存性増殖 / U0126 / Rasがん遺伝子 / Srcがん遺伝子 / MAPキナーゼ / p7056キナーゼ / Srcチロシンキナーゼ / Ablチロシンキナーゼ / アポトーシス / 細胞接着 / RB / p21^<waf1> / cyclin D1 / CDKインヒビター / Ets-1 / がん化シグナル / 細胞周期 / チロシンキナーゼ阻害剤 / マクロライド / がん転移 / 転写因子 / 接着 / 肝臓再生 / 小型肝細胞 / コロニー / 毛細胆管 / 収縮機構 / 細胞間相互作用 / マイクロバイオメカニクス / 胆汁輸送 / 肝細胞 / 収縮運動 / 管腔形成 / 同期的収縮 / 再生肝臓 / 化合物 / 分子標的 / 阻害剤 / 研究支援 / データベース / 抗がん剤 / XBP1 / 固形がん悪性化 / 固形がん悪性 / タンパク質合成阻害剤 / ミトファジー / 若手支援 / 国際研究者交流 / 遺伝子改変マウス / 病理形態学 / ゲノムコーホート研究 / 次世代分子解析技術 / アカデミア創薬 / ゲノム・エピゲノム解析支援 / 個別化がん予防 / 国際交流 / ATL発症予防 / 分子疫学コーホート研究 / がん化学予防 / ATL発がん機序 / ATL発症リスク / がん分子標的薬剤 / 天然物 / 天然物リガンド / 国際交流（ドイツ） / 国際交流（米国） / 国際交流（韓国） / 国際交流（スウェーデン） / 異分野融合 / 国際研究者交流（米国） / 国際研究者交流（中国） / 国際研究者交流（韓国） / 天然物ケミカルバイオロジー / 分子設計 / イメージング / センサータンパク質 / UPR / 比較解析 / PERK / IRE1α / BiFC / ATF6 / IRE1 / 人工配位子 / ファルネシルトランスフェラーゼ / 癌遺伝子 / Ras蛋白質 / man-made chelator / farnesyltransferase / oncogene / Ras protein / 転写結合モチーフ / 転写制御 / 隠れマルコフモデル / プロモーター / クロマチン免疫沈降 / 血小板由来増殖因子 / 主成分分析 / クラスタリング / モチーフ変異体 / 決定木 / レポーターアッセイ / バイオインフォマティクス / 分子細胞生物学 / 転写因子結合部位 / ゲルシフトアッセイ / transcription biding site / transcriptional regulation / hidden Markov model / promoter sequence / chromatin immunoprecipitation / EGFR / 神経変性 / ゲルダナマイシン / 神経保護作用 / Hsp-90 / HSP-90 / 2D-DIEG / プロテオーム解析 / EMT / 制がん剤耐性 / シスプラチン / TGF-beta / 上皮間葉転換 / カドヘリン / 薬剤感受性 / 化学コミュニケーション / 複合培養 / 生物活性リガンド / 生合成 / マイトファジー / 創薬シーズ / 蛋白分解 / iPS細胞 / ES細胞 / ポリアミン / ミトコンドリア / 脂肪酸β酸化 / miRNA / 遠隔効果 / 骨格筋 / 甲状腺 / 肝臓 / 臓器円環 / 脂肪酸代謝 / 臓器連関 / パーキンソン病(PD) / α-synuclein (αS) / レヴィ小体 / 多系統萎縮症 (MSA) / バイオマーカー / モデル動物作製 / ゲノム編集 / 病理形態解析 / 生理機能解析 / 分子探索・プロファイリング / 分子プロファイリング / 分子探索・ブロファイリング / 行動解析 / 自律神経 / 機械学習 Less

  • Research Projects

    (35 results)

  • Research Products

    (576 results)

  • Co-Researchers

    (467 People)

  •  Development of anti-Parkinson's disease drugs enhancing neuronal autophagy

    • Principal Investigator
      斉木 臣二
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52020:Neurology-related
    • Research Institution
      Juntendo University

  •  Elucidation of transmission and aggregation mechanisms of alpha-synuclein as a major component of Lewy body and development of disease-modifying therapies for synucleinopathies

    • Principal Investigator
      服部 信孝
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 52:General internal medicine and related fields
    • Research Institution
      Juntendo University

  •  Studies on the regulatory mechanism of aggresome formatiion and clearancePrincipal Investigator

    • Principal Investigator
      井本 正哉
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 37020:Chemistry and chemical methodology of biomolecules-related
    • Research Institution
      Juntendo University

  •  Identification of Parkinson disease-specific mitochondrial pathogenesis for disease-modifying therapy

    • Principal Investigator
      斉木 臣二
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
    • Review Section
      Medium-sized Section 52:General internal medicine and related fields
    • Research Institution
      Juntendo University

  •  Identification of Parkinson's disease progression markers based on skeletal muscle-brain axis

    • Principal Investigator
      斉木 臣二
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52020:Neurology-related
    • Research Institution
      Juntendo University

  •  Chemical Biology for Parkinson's diseasePrincipal Investigator

    • Principal Investigator
      Imoto Masaya
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 37020:Chemistry and chemical methodology of biomolecules-related
    • Research Institution
      Juntendo University
      Keio University

  •  Chemical communications in microbial interactions and development of useful bioactive ligands

    • Principal Investigator
      掛谷 秀昭
    • Project Period (FY)
      2017 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Science and Engineering
    • Research Institution
      Kyoto University

  •  先端モデル動物支援プラットフォーム

    • Principal Investigator
      井上 純一郎, 今井 浩三
    • Project Period (FY)
      2016 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas ― Platforms for Advanced Technologies and Research Resources
    • Research Institution
      The University of Tokyo

  •  Chemical Biological studies for autophagyPrincipal Investigator

    • Principal Investigator
      IMOTO MASAYA
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biomolecular chemistry
    • Research Institution
      Keio University

  •  Development of anti-PD chemicals modulating autophagic activity based on lysosomal function

    • Principal Investigator
      Shinji Saiki
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      Juntendo University

  •  Molecular mechanism of neuroprotective activity of geldanamycin

    • Principal Investigator
      NISHIKAWA Toshio
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Biomolecular chemistry
    • Research Institution
      Nagoya University

  •  Discovery of MET-inducing compounds as anti-cancer chemotherapeutic agents

    • Principal Investigator
      Tashiro Etsu
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Chemical biology
    • Research Institution
      Keio University

  •  Studies on Ciona notochord tubulogenesis by chemical biology approachPrincipal Investigator

    • Principal Investigator
      IMOTO Masaya
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Chemical biology
    • Research Institution
      Keio University

  •  Development of autophagy enhancing chemicals based on Parkinson's disease pathogenesis.

    • Principal Investigator
      SAIKI Shinji
    • Project Period (FY)
      2013 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Juntendo University

  •  Chemical biology using natural products

    • Principal Investigator
      UEDA Minoru
    • Project Period (FY)
      2011 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Science and Engineering
    • Research Institution
      Tohoku University

  •  Discovery of natural products that modulate cellular responsesPrincipal Investigator

    • Principal Investigator
      Imoto Masaya
    • Project Period (FY)
      2011 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Science and Engineering
    • Research Institution
      Keio University

  •  Imaging the activation behavior of ER stress sensors

    • Principal Investigator
      TASHIRO ETSU
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Chemical biology
    • Research Institution
      Keio University

  •  Scientific Support Programs for Cancer Research Grant-in-Aid for Scientific Research on Innovative Areas

    • Principal Investigator
      IMAI Kohzoh, 中村 祐輔
    • Project Period (FY)
      2010 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Research Institution
      The University of Tokyo

  •  Chemical Biology on Cancer and Neurodegenerative diseasePrincipal Investigator

    • Principal Investigator
      IMOTO Masaya
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Living organism molecular science
    • Research Institution
      Keio University

  •  A combination study of chemical and systems biology identifying novelfeatures of signaling pathway in cancer cell migrationPrincipal Investigator

    • Principal Investigator
      IMOTO Masaya
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Living organism molecular science
    • Research Institution
      Keio University

  •  Effects of mitophagy on cell death in Parkinson's disease model cells

    • Principal Investigator
      SAIKI Shinji
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Neurology
    • Research Institution
      Juntendo University

  •  がん悪性化機構を標的とした抗がん剤リード化合物の開発Principal Investigator

    • Principal Investigator
      井本 正哉
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Keio University

  •  Studies on the role of XBP1 in tumor malignancy

    • Principal Investigator
      TASHIRO Etsu
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Chemical biology
    • Research Institution
      Keio University

  •  Studies on regulatory mechanism for cell migration based on chemical geneticsPrincipal Investigator

    • Principal Investigator
      IMOTO Masaya
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Living organism molecular science
    • Research Institution
      Keio University

  •  Development of an information-intensive basis for cancer chemotherapy

    • Principal Investigator
      YAMORI Takao
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Japanese Foundation For Cancer Research

  •  SYS tern Analysis of Transcriptional Regulation Program

    • Principal Investigator
      SAKAKIBARA Yasubumi
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Bioinformatics/Life informatics
    • Research Institution
      KEIO UNIVERSITY

  •  計算的プロテオーム解析による核外移行シグナルの同定Principal Investigator

    • Principal Investigator
      井本 正哉
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Bioinformatics/Life informatics
    • Research Institution
      Keio University

  •  再生毛細胆管の収縮を生み出す小型肝細胞収縮の同期機構のバイオメカニクス

    • Principal Investigator
      谷下 一夫
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      Keio University

  •  がん細胞の悪性化を阻害する物質の探索Principal Investigator

    • Principal Investigator
      井本 正哉
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Keio University

  •  細胞がん化のシグナル伝達の解析と特異的阻害剤の探索

    • Principal Investigator
      上原 至雅
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      National Institute of Infectious Diseases

  •  癌細胞のホメオスタシスを破壊する薬剤の開発と分子機構解析Principal Investigator

    • Principal Investigator
      井本 正哉
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Keio University

  •  Molecular Design of Ras Farnesyltransferase Inhibitors

    • Principal Investigator
      OTSUKA Masami
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      医薬分子機能学
    • Research Institution
      Kumamoto University

  •  がん増悪因子とその制御に作用する制がん物質の研究

    • Principal Investigator
      UEHARA Yoshimasa
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      国立予防衛生研究所

  •  癌増悪因子とその制御に作用する制癌物質の研究

    • Principal Investigator
      石塚 雅章
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Microbial Chemistry Research Foundation

  •  細胞増殖制御因子および耐性因子に作用する制癌剤の探索とその応用

    • Principal Investigator
      石塚 雅章
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Microbial Chemistry Research Foundation

All 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Book Patent

  • [Book] カレントレビュー192015
    • Author(s)
      井本正哉
    • Total Pages
      189
    • Publisher
      化学同人
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Book] 最新がん薬物療法学2015
    • Author(s)
      田代悦，井本正哉
    • Total Pages
      704
    • Publisher
      （株）日本臨床社
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Book] 最新がん薬物療法学2015
    • Author(s)
      北川光洋、田代悦、井本正哉
    • Publisher
      (株)日本臨床社
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Book] 最新がん薬物療法学2014
    • Author(s)
      田代悦，井本正哉
    • Total Pages
      704
    • Publisher
      日本臨床社
    • Data Source
      KAKENHI-PROJECT-26350974

  • [Book] 特集オートファジーに挑むケミカルバイオロジー「天然物化学とケミカルバイオロジーの挑戦」2014
    • Author(s)
      田代悦、井本正哉
    • Publisher
      (株)化学工業社
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Book] オートファジーに挑むケミカルバイオロジー　「天然物化学とケミカルバイオロジーの挑戦」2014
    • Author(s)
      北川光洋，田代悦，井本正哉
    • Total Pages
      79
    • Publisher
      （株）化学工業社
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Book] 特集・制がん剤の分子標的スクリーニング成績 「化学療法基盤情報支援班」報告-制がん候補物質のスクリーニング成績・第14報『癌と化学療法オンライン』2013
    • Author(s)
      矢守隆夫, 上原至雅, 深澤秀輔, 吉田稔, 井本正哉, 清宮啓之, 水上民夫, 川田学, 長田裕之, 松浦正明.
    • Publisher
      癌と化学療法社
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Book] 特集・制がん剤の分子標的スクリーニング成績 「化学療法基盤情報支援班」報告‐制がん候補物質のスクリーニング成績・第15報『癌と化学療法オンライン』2013
    • Author(s)
      矢守隆夫, 上原至雅, 深澤秀輔, 吉田稔, 井本正哉, 清宮啓之, 馬島哲夫, 水上民夫, 川田学, 長田裕之, 旦慎吾, 松浦正明, 掛谷秀昭, 冨田章弘.
    • Publisher
      癌と化学療法社
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Book] 特集・制がん剤の分子標的スクリーニング成績 化学療法基盤情報支援班報告-制がん候補物質のスクリーニング成績・第14報-2013
    • Author(s)
      矢守隆夫, 上原至雅, 深澤秀輔, 吉田稔, 井本正哉, 清宮啓之, 水上民夫, 川田学, 長田裕之, 松浦正明.
    • Publisher
      癌と化学療法社
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Book] 特集・制がん剤の分子標的スクリーニング成績 化学療法基盤支援活動報告-制がん候補物質のスクリーニング成績・第15報2013
    • Author(s)
      矢守隆夫, 上原至雅, 深澤秀輔, 吉田稔, 井本正哉, 清宮啓之, 馬島哲夫, 水上民夫, 川田学, 長田裕之, 旦慎吾, 松浦正明, 掛谷秀昭, 冨田章弘
    • Publisher
      癌と化学療法社
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Book] Ⅱ． 基礎研究 ３． ケミカルバイオロジーと構造生物学 (２) 制がん剤シードの探索（増刊日本臨床 11月号）2012
    • Author(s)
      藤巻貴宏, 井本正哉.
    • Publisher
      日本臨床社
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Book] 特集・制がん剤の分子標的スクリーニング成績「化学療法基盤情報支援班」報告-制がん候補物質のスクリーニング成績・第13報-2010
    • Author(s)
      矢守隆夫、上原至雅、吉田稔、井本正哉、清宮啓之、水上民夫、川田学、長田裕之、松浦正明、深澤秀輔
    • Total Pages
      158
    • Publisher
      癌と化学療法
    • Data Source
      KAKENHI-PROJECT-17012025

  • [Book] 「化学療法基盤情報支援班」報告-制がん候補物質のスクリーニング成績・第13報2010
    • Author(s)
      矢守隆夫、上原至誠、吉田稔、井本正哉、清宮啓之、水上民夫, 他
    • Total Pages
      158
    • Publisher
      癌と化学療法社
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Book] 癌と化学療法(特集・制がん剤の分子標的スクリーニング成績「化学療法基盤情報支援班」報告-制がん候補物質のスクリーニング成績・第13報-, 37)2010
    • Author(s)
      矢守隆夫, 上原至雅, 吉田稔, 井本正哉, 清宮啓之, 水上民夫, 川田学, 長田裕之, 松浦正明, 深澤秀輔
    • Data Source
      KAKENHI-PROJECT-17012025

  • [Book] 実験医学(岡野栄之・岩坪威・佐谷秀行編, ケミカルバイオロジーに基づく創薬研究, 分子標的薬開発の新たなる挑戦)2009
    • Author(s)
      河村達郎, 田代悦, 井本正哉
    • Total Pages
      233
    • Data Source
      KAKENHI-PROJECT-17012025

  • [Book] 特集・制がん剤の分子標的スクリーニング成績 「化学療法基盤情報支援班」報告-制がん候補物質のスクリーニング成績・第12報-.2007
    • Author(s)
      矢守隆夫, 上原至雅, 吉田稔, 井本正哉, 清宮啓之, 水上民夫, 川田学, 長田裕之, 松浦正明.
    • Publisher
      癌と化学療法
    • Data Source
      KAKENHI-PROJECT-17012025

  • [Book] 癌と化学療法(特集・制がん剤の分子標的スクリーニング成績 「化学療法基盤情報支援班」報告-制がん候補物質のスクリーニング成績・第12報-, 34)2007
    • Author(s)
      矢守隆夫, 上原至雅, 吉田稔, 井本正哉, 清宮啓之, 水上民夫, 川田学, 長田裕之, 松浦正明
    • Data Source
      KAKENHI-PROJECT-17012025

  • [Book] 文部科学省科学研究費補助金によるがん研究に係る特定領域研究 II「化学療法基盤情報支援班」報告2007
    • Author(s)
      矢守隆夫, 上原至雅, 吉田稔, 井本正哉, 清宮啓之, 水上民夫, 川田学, 長田裕之, 松浦正明
    • Publisher
      癌と化学療法(印刷中)
    • Data Source
      KAKENHI-PROJECT-17012025

  • [Journal Article] Fhod3 Controls the Dendritic Spine Morphology of Specific Subpopulations of Pyramidal Neurons in the Mouse Cerebral Cortex2021
    • Author(s)
      Hikmawan Wahyu Sulistomo, Takayuki Nemoto, Yohko Kage, Hajime Fujii, Taku Uchida, Kogo Takamiya, Hideki Sumimoto, Hiroaki Kataoka, Haruhiko Bito, Ryu Takeya
    • Journal Title

      Cerebral Cortex

      Volume: 31 Pages: 2205-2219

    • DOI

      10.1093/cercor/bhaa355

    • Description
      in press
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07355, KAKENHI-PROJECT-19K11793, KAKENHI-PROJECT-18K06701, KAKENHI-PROJECT-16H06276

  • [Journal Article] Kv11 (ether-a-go-go-related gene)voltage-dependent K^+ channels promote resonance and oscillation of subthreshold membrane potentials2021
    • Author(s)
      Toshinori Matsuoka, Miwako Yamasaki, Manabu Abe, Yukiko Matsuda, Hiroyuki Morino, Hideshi Kawakami, Kenji Sakimura, Masahiko Watanabe, Kouichi Hashimoto
    • Journal Title

      Journal of Physiology

      Volume: 599(2) Pages: 547-569

    • DOI

      10.1113/jp280342

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07994, KAKENHI-PROJECT-18H02540, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H06280

  • [Journal Article] Association of urinary free cortisol with bone formation in patients with mild autonomous cortisol secretion.2021
    • Author(s)
      Ishida A, Igarashi K, Ruike Y, Ishiwata K, Naito K, Kono S, Deguchi H, Fujimoto M, Shiga A, Suzuki S, Yoshida T, Tanaka T, Tatsuno I, Yokote K, Koide H.
    • Journal Title

      Cl in Endocrinol (Oxf).

      Volume: 94 Pages: 544-550

    • DOI

      10.1111/cen.14385

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09875, KAKENHI-PROJECT-16H06276

  • [Journal Article] Highly Sensitive Determination of Amino Acids by LC-MS under Neutral Conditions2021
    • Author(s)
      Morimoto, R., Matsumoto, T., Minote, M., Yanagisawa, M., Yamada, R., Kuranaga, T., Kakeya, H.
    • Journal Title

      CHEMICAL & PHARMACEUTICAL BULLETIN

      Volume: 69 Issue: 3 Pages: 265-270

    • DOI

      10.1248/cpb.c20-00958

    • NAID

      130007993065

    • ISSN
      0009-2363, 1347-5223
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-17H06401

  • [Journal Article] Palmitoyl piperidinopiperidine, a novel derivative of 10-hydroxy-2-decenoic acid, as a potent and selective anticancer agent against human colon carcinoma cell lines2021
    • Author(s)
      Ando S, Fukamachi K, Yoshimoto E, Matsumoto H, Iinuma M and Suzui M.
    • Journal Title

      Int J Oncol

      Volume: 58 Pages: 251-265

    • DOI

      10.3892/ijo.2020.5160

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K07223, KAKENHI-PROJECT-16H06276

  • [Journal Article] Discovery of “heat shock metabolites” produced by thermotolerant actinomycetes in high-temperature culture.2020
    • Author(s)
      Saito S, Kato W, Ikeda H, Katsuyama Y, *Ohnishi Y, *Imoto M.
    • Journal Title

      J. Antibiotics

      Volume: 73 Pages: 203-210

    • DOI

      10.1038/s41429-020-0279-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-17H06401, KAKENHI-PROJECT-18H02099

  • [Journal Article] Cardiomyocyte Sirt (Sirt7)7 ameliorates stress-induced cardiac hypertrophy by interacting with and deacetylating GATA42020
    • Author(s)
      Yamamura S, Izumiya Y, Araki S, Nakagata N, Bober E, Braun T, Sakamoto K, Kaikita K, Morimoto T, Yamagata K, Tsujita K
    • Journal Title

      Hypertension

      Volume: 75 Pages: 98-108

    • DOI

      10.1161/hypertensionaha.119.13357

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08110, KAKENHI-PROJECT-19K22639, KAKENHI-PROJECT-19H03711, KAKENHI-PROJECT-17K08279, KAKENHI-PROJECT-16H06276

  • [Journal Article] Behavioral and electrophysiological evidence for a neuroprotective role of aquaporin-4 in the 5xFAD transgenic mice model2020
    • Author(s)
      Abe Y, Ikegawa N, Yoshida K, Muramatsu K, Hattori S, Murakami M, Tanaka T, Goda W, Hashimoto T, Miyakawa T, Iwatsubo T, Hata J, Niikura T, Yasui M, et al.
    • Journal Title

      Acta Neuropathol. Commun.

      Volume: 8 Pages: 67-67

    • DOI

      10.1186/s40478-020-00936-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07364, KAKENHI-PROJECT-19K07128, KAKENHI-PUBLICLY-19H05027, KAKENHI-PLANNED-20H05896, KAKENHI-PROJECT-18H02606, KAKENHI-PROJECT-16H06276

  • [Journal Article] Role of nuclear claudin-4 in renal cell carcinoma.2020
    • Author(s)
      Owari T, Takamitsu Sasaki T, Fujii K, Fujiwara-Tani R, Kishi S, Mori S, Mori T, Goto K, Kawahara I, .....Luo Y, Tanaka N, Kondoh M, Fujimoto K, Kuniyasu H
    • Journal Title

      Int J Mol Sci

      Volume: 21 Pages: 8340-8340

    • DOI

      10.3390/ijms21218340

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K21659, KAKENHI-PROJECT-19K19915, KAKENHI-PROJECT-20K18007, KAKENHI-PROJECT-20K19349, KAKENHI-PROJECT-18K10788, KAKENHI-PROJECT-18K16671, KAKENHI-PROJECT-16H06276

  • [Journal Article] Highly sensitive labeling reagents for scarce natural products2020
    • Author(s)
      Kuranaga, T., Minote, M., Morimoto, R., Pan, C., Ogawa, H., Kakeya, H
    • Journal Title

      ASC Chem. Biol.

      Volume: 15 Pages: 2499-2506

    • DOI

      10.1021/acschembio.0c00517

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-17H06401, KAKENHI-PROJECT-19H02840

  • [Journal Article] Meiosis-specific C19orf57/4930432K21Rik/BRME1 modulates localization of RAD51 and DMC1 to DSBs in mouse meiotic recombination2020
    • Author(s)
      Takemoto K., Tani N., Takada Y., Fujimura S., Tanno N., Yamane M., Okamura K., Sugimoto M., Araki K., Ishiguro K.
    • Journal Title

      Cell Reports

      Volume: 31 Pages: 107686-107686

    • DOI

      10.1016/j.celrep.2020.107686

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-19H05743, KAKENHI-PROJECT-20H03265, KAKENHI-PROJECT-16H06276

  • [Journal Article] Microinjection support system for small biological subject2020
    • Author(s)
      Sugimoto Y., Naniwa K., Aonuma H. and Osuka K.
    • Journal Title

      HardwareX

      Volume: 7

    • DOI

      10.1016/j.ohx.2020.e00103

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K18860, KAKENHI-PROJECT-16H06276

  • [Journal Article] Miclxin, a novel MIC60 inhibitor, induces apoptosis via mitochondrial stress in beta-catenin mutant tumor cells2020
    • Author(s)
      Ikeda H, Muroi M, Kondoh Y, Ishikawa S, Kakeya H, Osada H, Imoto M
    • Journal Title

      ACS Chem. Biol

      Volume: 15 Pages: 2195-2204

    • DOI

      10.1021/acschembio.0c00381

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K05857, KAKENHI-PLANNED-17H06401, KAKENHI-PLANNED-17H06412, KAKENHI-PLANNED-18H05503, KAKENHI-PROJECT-18H02099, KAKENHI-PROJECT-18K05366, KAKENHI-PROJECT-16H06276

  • [Journal Article] Neural stem cell-specific ITPA deficiency causes neural depolarization and epilepsy2020
    • Author(s)
      Yuichiro Koga, Daisuke Tsuchimoto, Yoshinori Hayashi, Nona Abolhassani, Yasuto Yoneshima, Kunihiko Sakumi, Hiroshi Nakanishi, Shinya Toyokuni, Yusaku Nakabeppu
    • Journal Title

      JCI Insight

      Volume: 5 Issue: 22

    • DOI

      10.1172/jci.insight.140229

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K09896, KAKENHI-PROJECT-18K06960, KAKENHI-PROJECT-18K19650, KAKENHI-PROJECT-16H06276

  • [Journal Article] A FLCN-TFE3 Feedback Loop Prevents Excessive Glycogenesis and Phagocyte Activation by Regulating Lysosome Activity2020
    • Author(s)
      M. Endoh, M. Baba, T. Endoh, A. Hirayama, A. Nakamura-Ishizu, T. Umemoto, M. Hashimoto, K. Nagashima, T. Soga, M. Lang, L. S. Schmidt, W. M. Linehan, T. Suda
    • Journal Title

      Cell Reports

      Volume: 30 Pages: 1823-1834

    • DOI

      10.1016/j.celrep.2020.01.042

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K06693, KAKENHI-PROJECT-19K22641, KAKENHI-PROJECT-18H02938, KAKENHI-PROJECT-19H03688, KAKENHI-PROJECT-18K19619, KAKENHI-PROJECT-18H05284, KAKENHI-PROJECT-16H06276

  • [Journal Article] Steroid metabolites for diagnosing and predicting clinicopathological features in cortisol-producing adrenocortical carcinoma.2020
    • Author(s)
      Suzuki S, Minamidate T, Shiga A, Ruike Y, Ishiwata K, Naito K, Ishida A, Deguchi H, Fujimoto M, Koide H, Tatsuno I, Ikeda JI, Yamazaki Y, Sasano H, Yokote K.
    • Journal Title

      BMC Endocr Disord.

      Volume: 20 Pages: 1-9

    • DOI

      10.1186/s12902-020-00652-y

    • Description
      in press
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K17974, KAKENHI-PROJECT-17K09875, KAKENHI-PROJECT-16H06276

  • [Journal Article] Curcumin beta-D-glucuronide (CMG) exhibits anti-tumor effects on oxaliplatin-resistant colon cancer with less toxicity2020
    • Author(s)
      Ozawa-Umeta, H., Kishimoto, A., Imaizumi, A., Hashimoto, T., Kakeya, H., Kanai, M.
    • Journal Title

      Cancer Sci.

      Volume: 111 Pages: 1785-1793

    • DOI

      10.1111/cas.14383

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-17H06401, KAKENHI-PROJECT-19H02840

  • [Journal Article] Earwig fan designing : biomimetic and evolutionary biology applications2020
    • Author(s)
      Kazuya Saito, Ricardo Prez-de la Fuente, Kichi Arimoto, Young ah Seong, Hitoshi Aonuma, Ryuma Niiyama, Zhong You
    • Journal Title

      Proceedings of the National Academy of Sciences U.S.A.

      Volume: 117 Issue: 30 Pages: 17622-17626

    • DOI

      10.1073/pnas.2005769117

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H04911, KAKENHI-PROJECT-16H06276

  • [Journal Article] Novel Method for Analyzing Flexible Locomotion Patterns of Animals by Using Polar Histogram2020
    • Author(s)
      Naniwa K., Sugimoto Y., Osuka K. and Aonuma H.
    • Journal Title

      J. Robot. Mechatron.

      Volume: 32 Issue: 4 Pages: 812-821

    • DOI

      10.20965/jrm.2020.p0812

    • NAID

      130007888807

    • ISSN
      0915-3942, 1883-8049
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Journal Article] Polygenic Risk Scores for Late Smoking Initiation Associated with the Risk of Schizophrenia2020
    • Author(s)
      Ohi K, Nishizawa D, Muto Y, Sugiyama S, Hasegawa J, Soda M, Kitaichi K, Hashimoto R, Shioiri T, Ikeda K
    • Journal Title

      NPJ Schizophr

      Volume: 6 Issue: 1 Pages: 36-36

    • DOI

      10.1038/s41537-020-00126-z

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08081, KAKENHI-PROJECT-20K09259, KAKENHI-PROJECT-19KK0225, KAKENHI-PROJECT-19H05467, KAKENHI-PROJECT-20H03611, KAKENHI-PROJECT-16H06276

  • [Journal Article] MDGA1-deficiency attenuates prepulse inhibition with alterations of dopamine and serotonin metabolism : An ex vivo HPLC-ECD analysis.2020
    • Author(s)
      Hossain MR, Jamal M, Tanoue Y, Ojima D, Takahashi H, Kubota T, Ansary TM, Ito A, Tanaka N, Kinoshita H, Kishimoto Y, Yamamoto T
    • Journal Title

      Neurosci, Lett.

      Volume: 716 Pages: 134677-134677

    • DOI

      10.1016/j.neulet.2019.134677

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07065, KAKENHI-PROJECT-19K07337, KAKENHI-PROJECT-16K08237, KAKENHI-PROJECT-16H06276

  • [Journal Article] Genome-wide survey of ribosome collision2020
    • Author(s)
      Han P., Shichino Y., Schneider-Poetsch T., Mito M., Hashimoto S., Udagawa T., Kohno K., Yoshida M., Mishima Y., Inada T., and Iwasaki S.
    • Journal Title

      Cell Rep.

      Volume: 31(5) Issue: 5 Pages: 107610-107610

    • DOI

      10.1016/j.celrep.2020.107610

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-18H05503, KAKENHI-PROJECT-19H05640, KAKENHI-PROJECT-16H06276

  • [Journal Article] BRUP-1, an intracellular bilirubin modulator, exerts neuroprotective activity in a cellular Parkinson's disease model.2020
    • Author(s)
      Kataura T, Saiki S, Ishikawa K, Akamatsu W, Sasazawa Y, Hattori N, Imoto M
    • Journal Title

      J Neurochem

      Volume: － Pages: 81-97

    • DOI

      10.1111/jnc.14997

    • Description
      in press
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19J12969, KAKENHI-PROJECT-18K15463, KAKENHI-PROJECT-18K15464, KAKENHI-PROJECT-16H06276, KAKENHI-PLANNED-17H06401, KAKENHI-PUBLICLY-20H05340, KAKENHI-PROJECT-18H02099

  • [Journal Article] Visually cued fear conditioning test for memory impairment related to cortical function2020
    • Author(s)
      Kuboyama K, Shirakawa Y, Kawada K, Fujii N, Ojima D, Kishimoto Y, Yamamoto T, Yamada MK
    • Journal Title

      Neuropsychopharmacol. Rep.

      Volume: 40 Pages: 371-375

    • DOI

      10.1002/npr2.12146

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07065, KAKENHI-PROJECT-16H06276

  • [Journal Article] Lung fibroblasts produce IL-33 in response to stimulation with retinoblastoma-binding protein 9 via production of prostaglandin E22020
    • Author(s)
      T. Adachi, K. Yasuda, T. Muto, S. Serada, T. Yoshimoto, K. J. Ishii, E. Kuroda, K. Araki, M. Ohmuraya, T. Naka and K. Nakanishi
    • Journal Title

      International Immunology

      Volume: 32 Issue: 10 Pages: 637-652

    • DOI

      10.1093/intimm/dxaa031

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08405, KAKENHI-PROJECT-20K07469, KAKENHI-PROJECT-16H06276

  • [Journal Article] Formin-like 1 (FMNL1) Is Associated with Glioblastoma Multiforme Mesenchymal Subtype and Independently Predicts Poor Prognosis.2020
    • Author(s)
      Higa N, Shinsato Y, Kamil M, Hirano T, Takajo T, Shimokawa M, Minami K, Yamamoto M, Kawahara K, Yonezawa H, Hirano H, Furukawa T, Yoshimoto K and Arita K
    • Journal Title

      Int J Mol Sci

      Volume: 20 Pages: 6355-63

    • DOI

      10.3390/ijms20246355

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K07221, KAKENHI-PROJECT-19K22566, KAKENHI-PROJECT-18K15248, KAKENHI-PROJECT-16K07121, KAKENHI-PROJECT-18K16590, KAKENHI-PROJECT-16H06276

  • [Journal Article] The synthetic curcumin analogue GO-Y030 effectively suppresses the development of pressure overload-induced heart failure in mice2020
    • Author(s)
      Shimizu K, Sunagawa Y, Funamoto M, Wakabayashi H, Genpei M, Miyazaki Y, Katanasaka Y, Sari N, Shimizu S, Katayama A, Shibata H, Iwabuchi Y, Kakeya H, Wada H, Hasegawa K, Morimoto T.
    • Journal Title

      Scientific Reports

      Volume: 10(1) Pages: 7172-7172

    • DOI

      10.1038/s41598-020-64207-w

    • NAID

      120006888478

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08279, KAKENHI-PLANNED-17H06401, KAKENHI-PROJECT-18K08121

  • [Journal Article] MEIOSIN directs the switch from mitosis to meiosis in mammalian germ cells2020
    • Author(s)
      Ishiguro K (Corresponding), Matsuura K, Tani N, Takeda N, Usuki S, Yamane M, Sugimoto M, Fujimura S, Hosokawa M, Chuma S, Ko S. H. M. Araki K, Niwa H
    • Journal Title

      Developmental Cell

      Volume: 52 Issue: 4 Pages: 429-445

    • DOI

      10.1016/j.devcel.2020.01.010

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19H05743, KAKENHI-PLANNED-19H05748, KAKENHI-PROJECT-17H03634, KAKENHI-PROJECT-18H02429, KAKENHI-PROJECT-18K19304, KAKENHI-PROJECT-16H06276

  • [Journal Article] A chemical genomics-aggrephagy integrated method studying functional analysis of autophagy inducers.2020
    • Author(s)
      Kataura T, Tashiro E, Nishikawa S, Onodera M, Shin-ya K, et al, Sasazawa Y, Hattori N, Saiki S, and Imoto M
    • Journal Title

      Autophagy

      Volume: Aug 7 Pages: 1-17

    • DOI

      10.1080/15548627.2020.1794590

    • Description
      in press
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K05732, KAKENHI-PROJECT-18KK0242, KAKENHI-PLANNED-17H06401, KAKENHI-PUBLICLY-20H05340, KAKENHI-PROJECT-18H02099, KAKENHI-PROJECT-16H06276

  • [Journal Article] Segmented Ibal-positive processes of microglia in autism model marmosets2019
    • Author(s)
      Tomomi Sanagi, Tetsuya Sasaki, Takafumi Minamimoto, Shin-ichi Kohsaka, and Noritaka Ichinohe
    • Journal Title

      Front Cell Neurosci, section Cellular Neuropathology

      Volume: 13 Pages: 344-350

    • DOI

      10.3389/fncel.2019.00344

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H00892, KAKENHI-PROJECT-16H06276

  • [Journal Article] Lamellarin-inspired potent topoisomerase I inhibitors with the unprecedented benzo [g] [1] benzopyrano [4, 3-b] indol-6 (13H)-one scaffold2019
    • Author(s)
      Tsutomu Fukuda, Yusuke Nanjo, Masahiro Fujimoto, Kenyu Yoshida, Yuko Natsui, Fumito Ishibashi, Fumiyasu Okazaki, Hideto To, Masatomo Iwao
    • Journal Title

      Bioorganic and Medicinal Chemistry

      Volume: 27 Issue: 2 Pages: 265-277

    • DOI

      10.1016/j.bmc.2018.11.037

    • NAID

      120006987774

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K14986, KAKENHI-PROJECT-16H06276

  • [Journal Article] Effects of highly absorbable curcumin in patients with impaired glucose tolerance and non-insulin dependent diabetes mellitus.2019
    • Author(s)
      Funamoto Masafumi、Shimizu Kana、Sunagawa Yoichi、Katanasaka Yasufumi、Miyazaki Yusuke、Kakeya Hideaki、Yamakage Hajime、Satoh-Asahara Noriko、Wada Hiromichi、Hasegawa Koji、Morimoto Tatsuya
    • Journal Title

      J. Diabetes Res.

      Volume: 2019 Pages: 1-7

    • DOI

      10.1155/2019/8208237

    • NAID

      120006888005

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08121, KAKENHI-PLANNED-17H06401

  • [Journal Article] mS-11, a mimetic of the mSin3-binding helix in NRSF, ameliorates social interaction deficits in a prenatal valproic acid-induced autism mouse model.2019
    • Author(s)
      Kawase H, Ago Y, Naito M, Higuchi M, Hara Y, Hasebe S, Tsukada S, Kasai A, Nakazawa T, Mishina T, Kouji H, Takuma K, Hashimoto H.
    • Journal Title

      Pharmacology Biochemistry and Behavior

      Volume: 176 Pages: 1-5

    • DOI

      10.1016/j.pbb.2018.11.003

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K19488, KAKENHI-PROJECT-16K08268, KAKENHI-PROJECT-15H04645, KAKENHI-PROJECT-16H06276, KAKENHI-PLANNED-18H05416, KAKENHI-PROJECT-17H03989, KAKENHI-PROJECT-18H02574

  • [Journal Article] Hydrogen ventilation combined with mild hypothermia improves short-term neurological outcomes in a 5-day neonatal hypoxia-ischaemia piglet model2019
    • Author(s)
      Htun Y, Nakamura S, Nakao Y, Mitsuie T, Nakamura M, Yamato S, Jinnai W, Koyano K, Ohta K, Morimoto A, Wakabayashi T, Sugino M, Fujioka K, Kato I, Kondo S, Yasuda S, Miki T, Ueno M, Kusaka T
    • Journal Title

      Scientific Reports

      Volume: 9 Pages: 4088-4088

    • DOI

      10.1038/s41598-019-40674-8

    • NAID

      120006599245

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10178, KAKENHI-PROJECT-18K07879, KAKENHI-PROJECT-16K19685, KAKENHI-PROJECT-18K15710, KAKENHI-PROJECT-15KK0311, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-17K10179, KAKENHI-PROJECT-16K10092

  • [Journal Article] RBM10-TFE3 Renal Cell Carcinoma Characterized by Paracentric Inversion with Consistent Closely Split Signals in Break-apart Fluorescence in situ Hybridization : Study of Ten Cases and a Literature Review2019
    • Author(s)
      Ikuma Kato, Mitsuko Furuya, Masaya Baba, Yoichi Kameda, Masanori Yasuda, Koshiro Nishimoto, Masafumi Oyama, Toshinari Yamasaki, Osamu Ogawa, Hitoshi Niino, Noboru Nakaigawa, Yuta Yano, Kazumasa Sakamoto, Yoji Urata, Kazuya Mikami, Shigetaka Yamasaki, Reiko Tanaka, Toshio Takagi, Tsunenori Kondo, Yoji Nagashima
    • Journal Title

      Histopathology

      Volume: 印刷中 Pages: 254-265

    • DOI

      10.1111/his.13866

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08745, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-18H02938, KAKENHI-PROJECT-17K11162, KAKENHI-PROJECT-18K19619, KAKENHI-PROJECT-16H06277

  • [Journal Article] Defecation initiates walking in the cricket Gryllus bimaculatus2019
    • Author(s)
      Naniwa K., Sugimoto Y., Osuka K. and Aonuma H.
    • Journal Title

      Journal of Insect Physiology

      Volume: 112 Pages: 117-122

    • DOI

      10.1016/j.jinsphys.2018.11.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H04381, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-17H06150

  • [Journal Article] SCF(Fbxw7) ubiquilylates KLF7 for degradation in a manner dependent on GSK-3-mediated phosphorylation.2019
    • Author(s)
      Sugiyama S., Yumimoto K., Inoue I., Nakayama KI.
    • Journal Title

      Genes Cells

      Volume: 印刷中 Pages: 354-365

    • DOI

      10.1111/gtc.12680

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K07171, KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-17H05795, KAKENHI-PUBLICLY-18H05037, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19J40055

  • [Journal Article] 天然物スクリーニングによる制がん剤シードの探索研究2019
    • Author(s)
      井本正哉
    • Journal Title

      The Japanese Journal of Antibiotics

      Volume: 72 Pages: 15-22

    • NAID

      40021853597

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-17H06401

  • [Journal Article] Quinidine therapy and therapeutic drug monitoring in four patients with KCNTI mutations.2019
    • Author(s)
      Yoshitomi S, Takahashi Y, Yamaguchi T, Oboshi T, Horino A, Ikeda H, Imai K, Okanishi T, Nakashima M, Saitsu H, Matsumoto N, Yoshimoto J, Fujita T, Ishii A, Hirose S, Inoue Y.
    • Journal Title

      Epileptic Disorders

      Volume: 21 Issue: 1 Pages: 48-54

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Journal Article] Discovery of Novel Spiroindoline Derivatives as Selective Tankyrase Inhibitors.2019
    • Author(s)
      Shirai F, Tsumura T, Yashiroda Y, Yuki H, Niwa H, Sato S, Chikada T, Koda Y, Washizuka K, Yoshimoto N, Abe M, Onuki T, Mazaki Y, Hirama C, Fukami T, Watanabe H, Honma T, Umehara T, Shirouzu M, Mizutani A, et al.
    • Journal Title

      J. Med. Chem.

      Volume: 62 Issue: 7 Pages: 3407-3427

    • DOI

      10.1021/acs.jmedchem.8b01888

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H06276, KAKENHI-PUBLICLY-18H04633, KAKENHI-PLANNED-18H05503, KAKENHI-PROJECT-19H03523, KAKENHI-PROJECT-26221204

  • [Journal Article] Calvarial Bone Implantation and in vivo Imaging of Tumor Cells in Mice2019
    • Author(s)
      Hashimoto K, Sato S, Ochi H, Takeda S, Futakuchi M
    • Journal Title

      Bio Protoc

      Volume: 9 Issue: 3

    • DOI

      10.21769/bioprotoc.3151

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Journal Article] High filamin-C expression predicts enhanced invasiveness and poor outcome in glioblastoma multiforme.2019
    • Author(s)
      Kamil M, Shinsato Y, Higa N, Hirano T, Idogawa M, Takajo T, Minami K, Shimokawa M, Yamamoto M, Kawahara K, Yonezawa H, Hirano H, Furukawa T, Yoshimoto K, Arita K.
    • Journal Title

      British Journal of Cancer

      Volume: 120 Pages: 819-826

    • DOI

      10.1038/s41416-019-0413-x

    • Description
      Epub ahead of print
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K07221, KAKENHI-PROJECT-18K15248, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-17K10871, KAKENHI-PROJECT-19K08372, KAKENHI-PROJECT-16K07121, KAKENHI-PROJECT-16K09285

  • [Journal Article] CAPZA1 determines the risk of gastric carcinogenesis by inhibiting Helicobacter pylori CagA-degraded autophagy.2019
    • Author(s)
      Tsugawa H., Mori H., Matsuzaki J., Sato A., Saito Y., Imoto M., Suematsu M., Suzuki H.
    • Journal Title

      Autophagy.

      Volume: 15 Pages: 1-17

    • DOI

      10.1080/15548627.2018.1515530

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08550, KAKENHI-PLANNED-17H06401, KAKENHI-PROJECT-16H05291, KAKENHI-PROJECT-17H03592, KAKENHI-PROJECT-16K08349, KAKENHI-PROJECT-18H02099

  • [Journal Article] Transcription factor homeobox D9 is involved in the malignant phenotype of cervical cancer through direct binding to the human papillomavirus oncogene promoter2019
    • Author(s)
      Hirao N, Iwata T, Tanaka K, Nishio H, Nakamura M, Morisada T, Morii K, Maruyama N, Katoh Y, Yaguchi T, Ohta S, Kukimoto I Aoki D, Kawakami Y
    • Journal Title

      Gynccol Oncology

      Volume: 155 Issue: 2 Pages: 31478-31487

    • DOI

      10.1016/j.ygyno.2019.08.026

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K11309, KAKENHI-PROJECT-19K09832, KAKENHI-PROJECT-18K16813, KAKENHI-PROJECT-16H06276

  • [Journal Article] Zn (OTf)2-mediated annulations of N-propargylated tetrahydrocarbolines : divergent synthesis of four distinct alkaloidal scaffolds2019
    • Author(s)
      Sadaiwa Yorimoto, Akira Tsubouchi, Haruki Mizoguchi, Hideaki Oikawa, Yoshiaki Tsunekawa, Tomoya Ichino, Satoshi Maeda and Hiroki Oguri
    • Journal Title

      Chemical Science

      Volume: 10 Pages: 5686-5698

    • DOI

      10.1039/c9sc01507h

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H02847, KAKENHI-PROJECT-16H06276

  • [Journal Article] Therapeutic and Preventive Effects of Osteoclastogenesis Inhibitory Factor on Osteolysis, Proliferation of Mammary Tumor Cell and Induction of Cancer Stem Cells in the Bone Microenvironment2018
    • Author(s)
      Futakuchi M, Nitanda T, Ando S, Matsumoto H, Yoshimoto E, Fukamachi K, Suzui M
    • Journal Title

      Int J Mol Sci

      Volume: 19 Issue: 3 Pages: 888-888

    • DOI

      10.3390/ijms19030888

    • NAID

      120006987309

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K06837, KAKENHI-PROJECT-17K07223, KAKENHI-PROJECT-16H06276

  • [Journal Article] Task-dependent function of striatal cholinergic interneurons2018
    • Author(s)
      Okada K, Nishizawa K, Setogawa S, Hashimoto K, Kobayashi K.
    • Journal Title

      Eur J Neurosci

      Volume: - Issue: 10 Pages: 1174-1183

    • DOI

      10.1111/ejn.13768

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H05400, KAKENHI-PROJECT-18H02545, KAKENHI-PROJECT-16J40090, KAKENHI-PROJECT-16H06276

  • [Journal Article] Safety evaluation of a human chimeric monoclonal antibody that recognizes the extracellular loop domain of claudin-2.2018
    • Author(s)
      Hashimoto Y, Hata T, Tada M, Iida M, Watari A, Okada Y, Doi T, Kuniyasu H, Yagi K, Kondoh M
    • Journal Title

      Eur J Pharm Sci

      Volume: 70 Pages: 161-167

    • DOI

      10.1016/j.ejps.2018.02.016

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H05164, KAKENHI-PROJECT-16K08370, KAKENHI-PROJECT-17K19923, KAKENHI-PROJECT-17K19487, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-17J03990

  • [Journal Article] Cell-based chemical fingerprinting identifies telomeres and lamin A as modifiers of DNA damage response in cancer cells2018
    • Author(s)
      Fujiwara C, Muramatsu Y, Nishii M, Tokunaka K, Tahara H, Ueno M, Yamori T, Sugimoto Y, Seimiya H.
    • Journal Title

      Scientific Reports

      Volume: 8 Pages: 14827-14827

    • DOI

      10.1038/s41598-018-33139-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K07502, KAKENHI-PROJECT-18K07302, KAKENHI-PROJECT-18K19487, KAKENHI-PUBLICLY-18H04633, KAKENHI-PROJECT-16H04716, KAKENHI-PROJECT-16H06276

  • [Journal Article] β-Arrestin1 and 2 differentially regulate PACAP-induced PAC1 receptor signaling and trafficking2018
    • Author(s)
      Shintani Y, Hayata-Takano A, Moriguchi K, Nakazawa T, Ago Y, Kasai A, Seiriki K, Shintani N, Hashimoto H.
    • Journal Title

      PLOS ONE

      Volume: 13 Issue: 5

    • DOI

      10.1371/journal.pone.0196946

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K19488, KAKENHI-PROJECT-16K08269, KAKENHI-PROJECT-15H04645, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-17H03989, KAKENHI-PROJECT-18H02574

  • [Journal Article] p53-inducible DPYSL4 associates with mitochondrial supercomplexes and regulates energy metabolism in adpocytes and cancer cells.2018
    • Author(s)
      Nagano H, Hashimoto N, Nakayama A, Suzuki S, Miyabayashi Y, Yamato A, Higuchi S, Fujimoto M, Sakuma I, Beppu M, Yokoyama M, Suzuki Y, Sugano S, Ikeda K, Tatsuno I, Manabe I, Yokote K, Inoue S, Tanaka T.
    • Journal Title

      Proc Natl Acad Sci U S A

      Volume: 115 Issue: 33 Pages: 8370-8375

    • DOI

      10.1073/pnas.1804243115

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09875, KAKENHI-PROJECT-17K09892, KAKENHI-PROJECT-18K07439, KAKENHI-PROJECT-18K08464, KAKENHI-PROJECT-17H01558, KAKENHI-PROJECT-17K19643, KAKENHI-PROJECT-17K16160, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-16H06279

  • [Journal Article] A cross-sectional study exploring useful indicators for low bone mineral density in male alcoholic patients.2018
    • Author(s)
      Horai T, Hishimoto A, Otsuka I, So T, Mouri K, Shimmyo N, Boku S, Okishio N, Sora I.
    • Journal Title

      Neuropsychiatr Dis Treat

      Volume: 14 Pages: 663-669

    • DOI

      10.2147/ndt.s153360

    • NAID

      120006425682

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07599, KAKENHI-PROJECT-16H06276

  • [Journal Article] Identification of protein kinase C isozymes involved in the anti-proliferative and pro-apoptotic activities of 10-methyl-aplog-1, a simplified analog of debromoaplysiatoxin, in several cancer cell lines.2018
    • Author(s)
      Hanaki Y, Shikata Y, Kikumori M, Hotta N, Imoto M, Irie K
    • Journal Title

      Biochem Biophys Ros Commun

      Volume: 495 Issue: 1 Pages: 438-445

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Journal Article] Early manifestation of dopressivc-like behavior in transgenic mico that express demcntia with Lcwy bodies-linked mutant beta-synuclein.2018
    • Author(s)
      Fujita M, Hagino Y, Takamatsu Y, Shimizu Y, Takamatsu Y, Ikeda K, Hashimoto M
    • Journal Title

      Neuropsychopharmacol Rep

      Volume: 印刷中 Pages: 95-97

    • DOI

      10.1002/npr2.12009

    • Description
      in press
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26293347, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-17H04324, KAKENHI-PROJECT-16K15565

  • [Journal Article] Curcumin and its demethoxyderivatives possess p300 HAT inhibitory activity and suppress hypertrophicresponses in cardiomyocytes.2018
    • Author(s)
      Yoichi Sunagawa, Masafumi Funamoto, Shogo Sono, Kana Shimizu, Satoshi Shimizu, Mai Genpei, Yusuke Miyazaki, Yasufumi Katanasaka, Eriko Morimoto, Morio Ueno, Maki Komiyama, Hideaki Kakeya, Hiromichi Wada, Koji Hasegawa, Tasuya Morimoto
    • Journal Title

      J. Pharmacol. Sci.

      Volume: 136 Pages: 212-217

    • DOI

      10.1016/j.jphs.2017.12.013

    • NAID

      120006501305

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-17H06401

  • [Journal Article] 14-3-3εa directs the pulsatile transport of basal factors toward the apical domain for lumen growth in tubulogenesis2018
    • Author(s)
      Yuji Mizotani, Mayu Suzuki, Kohji Hotta, Hidenori Watanabe, Kogiku Shiba, Kazuo Inaba, Etsu Tashiro, Kotaro Oka, Masaya Imoto
    • Journal Title

      Proc. Natl. Acad. Sci. USA

      Volume: 115

    • DOI

      10.1073/pnas.1808756115

    • NAID

      120007133686

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-17H06401, KAKENHI-PROJECT-16K07337, KAKENHI-PROJECT-18H02099, KAKENHI-PROJECT-16K07426

  • [Journal Article] Neuronal sirtl regulates macronutrient-based diet selection through fgf21 and oxytocin signalling in mice.2018
    • Author(s)
      Matsui S, Sasaki T, Kohno D, Yaku K, Inutsuka A, Yokota-Hashimoto H, Kikuchi O. Suga T. Kobayashi M. Yamanaka A, Harada A, Nakagawa T. Onaka T, Kitamura T.
    • Journal Title

      Nat Commun

      Volume: 9 Issue: 1 Pages: 1-17

    • DOI

      10.1038/s41467-018-07033-z

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08527, KAKENHI-PROJECT-17K08653, KAKENHI-PROJECT-18K17921, KAKENHI-PROJECT-18KK0223, KAKENHI-PUBLICLY-17H05563, KAKENHI-PUBLICLY-17H06061, KAKENHI-PLANNED-17H06422, KAKENHI-PUBLICLY-18H05124, KAKENHI-PROJECT-17H01971, KAKENHI-PROJECT-18H02523, KAKENHI-PROJECT-18H02594, KAKENHI-PROJECT-17K16139, KAKENHI-PROJECT-16H06276

  • [Journal Article] Supramammillary Nucleus Afferents to the Dentate Gyrus Co-release Glutamate and GABA and Potentiate Granule Cell Output2018
    • Author(s)
      Hashimotodani Y, Karube F, Yanagawa Y, Fujiyama F, Kano M
    • Journal Title

      Cell Rep

      Volume: 25 Pages: 2704-2715

    • DOI

      10.1016/j.celrep.2018.11.016

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K07043, KAKENHI-PLANNED-26112006, KAKENHI-PROJECT-16H03299, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-18H04012, KAKENHI-PROJECT-25000015

  • [Journal Article] A new method for identifying mouse pancreatic ducts2018
    • Author(s)
      Nakajima C, Kamimoto K, Miyajima K, Matsumoto M, Okazaki Y, Kobayashi-Hattori K, Shimizu M, Yamane T, Oishi Y, Iwatsuki K.
    • Journal Title

      Tissue Eng.

      Volume: 24 Issue: 8 Pages: 480-485

    • DOI

      10.1089/ten.tec.2018.0127

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Journal Article] Loss of chromosome Y in blood, but not in brain, of suicide completers.2018
    • Author(s)
      Kimura A, Hishimoto A, Otsuka I, Okazaki S, Boku S, Horai T, Izumi T, Takahashi M, Ueno Y, Shirakawa O, Sora I.
    • Journal Title

      PLoS One

      Volume: 13 Issue: 1

    • DOI

      10.1371/journal.pone.0190667

    • NAID

      120006382347

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04249, KAKENHI-PROJECT-15K19727, KAKENHI-PROJECT-16K10183, KAKENHI-PROJECT-16K19765, KAKENHI-PROJECT-16H06276

  • [Journal Article] Longer telomeres in elderly schizophrenia are associated with long-term hospitalization in the Japanese population.2018
    • Author(s)
      Zhang Y ; Hishimoto A ; Otsuka I ; Watanabe Y ; Numata S ; Yamamori H ; Boku S ; Horai T ; Someya T ; Ohmori T ; Hashimoto R ; Sora I
    • Journal Title

      J Psychiatr Res

      Volume: 103 Pages: 161-166

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Journal Article] Neurocognitive Impairments Are More Severe in the Binge-Eating/Purging Anorexia Nervosa Subtype Than in the Restricting Subtype.2018
    • Author(s)
      Tamiya Y ; Ouchi A ; Chen R ; Miyazawa S ; Akimoto Y ; Kaneda Y ; Sora I
    • Journal Title

      Front Psychiatry

      Volume: 138 Pages: 9-9

    • DOI

      10.3389/fpsyt.2018.00138

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Journal Article] Identification of Protein Kinase C Isozymes Involved in the Anti-Proliferative and Pro-Apoptotic Activities of 10-Methyl-aplog-1, a Simplified Analog of Debromoaplysiatoxin, in Several Cancer Cell Lines.2018
    • Author(s)
      Yusuke Hanaki, Yuki Shikata, Masayuki Kikumori, Natsuki Hotta, Masaya Imoto, Kazuhiro Irie
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 495 Pages: 438-445

    • DOI

      10.1016/j.bbrc.2017.11.052

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-17H06405, KAKENHI-PROJECT-15H03116, KAKENHI-PROJECT-16J04817, KAKENHI-PROJECT-18H02099

  • [Journal Article] Interaction between cardiac myosin-binding protein C and formin Fhod3.2018
    • Author(s)
      Natsuyama S, Kage Y. Fujimoto N, Ushijima T, Tsuruda T, Kitamura K, Shiose A, Asada Y, Sumimoto H, Takeya R.
    • Journal Title

      Proceedings of the National Academy of Sciences of the United States of America

      Volume: 115 Issue: 19

    • DOI

      10.1073/pnas.1716498115

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26460371, KAKENHI-PLANNED-26111009, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H06280

  • [Journal Article] Prednisolone-responsive Postpartum IgG4-related Hypophysitis.2018
    • Author(s)
      Koide H, Shiga A, Komai E, Yamato A, Fujimoto M, Tamura A, Kono T, Nakayama A, Takiguchi T, Higuchi S, Sakuma I, Nagano H, Hashimoto N, Suzuki S, Takeda Y, Shibuya M, Nishioka H, Yamada S, Inoshita N, Ishiwatari N, Horiguchi K, Yokote K, Tanaka T.
    • Journal Title

      Intern Med

      Volume: 57 Issue: 3 Pages: 367-375

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Journal Article] Glucagonoma With Necrolytic Migratory Erythema : Metabolic Profile and Detection of Biallelic Inactivation of DAXX Gene.2018
    • Author(s)
      Tamura A, Ogasawara T, Fujii Y, Kaneko H, Nakayama A, Higuchi S, Hashimoto N, Niyabayashi Y, Fujimoto M, Komai E, Kono T, Sakuma I, Nagano H, Suzuki S, Koide H, Yokote K, Iseki K, Oguma R, Matsue H, Nojima H, Sugiura K, Yoshitomi H, Ohtsuka M, Rahmutulla B, Kaneda A, Inoshita N, Ogawa S, Tanaka T.
    • Journal Title

      J Clin Endocrinol Metab

      Volume: 23 Issue: 7 Pages: 2417-2423

    • DOI

      10.1210/jc.2017-02646

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09875, KAKENHI-PROJECT-16KK0197, KAKENHI-PROJECT-18K07439, KAKENHI-PROJECT-18K08464, KAKENHI-PROJECT-18K15040, KAKENHI-PROJECT-17K16160, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H06277

  • [Journal Article] Chemistry and biology for the small molecules targeting characteristics of cancer cells2018
    • Author(s)
      Masaya Imoto
    • Journal Title

      Biosci Biotechnol Biochem

      Volume: 83 Pages: 1-10

    • DOI

      10.1080/09168451.2018.1518704

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-17H06401

  • [Journal Article] Increased serum levels and promoter polymorphisms of macrophage migration inhibitory factor in schizophrenia.2018
    • Author(s)
      Okazaki S, Hishimoto A, Otsuka I, Watanabe Y, Numata S, Boku S, Shimmyo N, Kinoshita M, Inoue E, Ohmori T, Someya T, Sora I.
    • Journal Title

      Prog Neuropsychopharmacol Biol Psychiatry

      Volume: 83 Pages: 33-41

    • DOI

      10.1016/j.pnpbp.2018.01.001

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K19727, KAKENHI-PROJECT-17K16371, KAKENHI-PROJECT-17H04249, KAKENHI-PROJECT-16K19765, KAKENHI-PROJECT-16H06276

  • [Journal Article] Investigation of chromosome Y loss in men with schizophrenia.2018
    • Author(s)
      Hirata T ; Hishimoto A ; Otsuka I ; Okazaki S ; Kimura A ; Horai T ; Sora I
    • Journal Title

      Neuropsychiatr Dis Treat

      Volume: 14 Pages: 2115-2122

    • DOI

      10.2147/ndt.s172886

    • NAID

      120006510199

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K15483, KAKENHI-PROJECT-18K15484, KAKENHI-PROJECT-17H04249, KAKENHI-PROJECT-16K19765, KAKENHI-PROJECT-16H06276

  • [Journal Article] 天然物スクリーニングとケミカルバイオロジーへの展開2018
    • Author(s)
      井本正哉
    • Journal Title

      化学と生物

      Volume: 56 Pages: 203-208

    • NAID

      130007602188

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-17H06401

  • [Journal Article] Folliculin Regulates Osteoclastogenesis Through Metabolic Regulation2018
    • Author(s)
      Masaya Baba, Mitsuhiro Endoh. Wenjuan Ma, Hirofumi Toyama. Akiyoshi Hirayama, Keiyo Takubo, Hiroyuki Hano. Hisashi Hasumi, Terumasa Umemoto, Michihiro Hashimoto, Nobuko Irie, Chiharu Esumi, Miho Kataoka, Naomi Nakagata, Tomoyoshi Soga, Masahiro Yao, Tomomi Kamba, Takashi Minami, Masaru Ishii, Toshio Suda
    • Journal Title

      Journal of Bone and Mineral Research

      Volume: 33 Issue: 10 Pages: 1785-1798

    • DOI

      10.1002/jbmr.3477

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18KT0026, KAKENHI-PROJECT-18K18455, KAKENHI-PROJECT-18K19619, KAKENHI-PUBLICLY-17H05530, KAKENHI-PROJECT-18H05284, KAKENHI-PROJECT-18H02614, KAKENHI-PROJECT-18H02938, KAKENHI-PROJECT-16K07372, KAKENHI-PROJECT-16K11020, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-17H03580

  • [Journal Article] Mitochondrial DNA copy number of peripheral blood in bipolar disorder : The present study and a meta-analysis.2018
    • Author(s)
      Yamaki N ; Otsuka I ; Numata S ; Yanagi M ; Mouri K ; Okazaki S ; Boku S ; Horai T ; Ohmori T ; Shirakawa O ; Sora I ; Hishimoto A
    • Journal Title

      Psychiatry Res

      Volume: 269 Pages: 115-117

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Journal Article] CIC-DUX4 induces small round cell sarcomas distinct from ewing sarcoma2017
    • Author(s)
      Yoshimoto T, Tanaka M, Homme M, Yamazaki Y, Takazawa Y, Antonescu CR, Nakamura T
    • Journal Title

      Cancer Res

      Volume: 印刷中 Pages: 2927-2937

    • DOI

      10.1158/0008-5472.can-16-3351

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26250029, KAKENHI-PROJECT-16K07131, KAKENHI-PROJECT-16H02676, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H06297

  • [Journal Article] Curcumin β-D-Glucuronide Plays an Important Role to Keep High Levels of Free-Form Curcumin in the Blood2017
    • Author(s)
      Ozawa, H., Imaizumi, A., Sumi, Y., Hashimoto, T., Kanai, M., Makino, Y., Tsuda, T., Takahashi, N., Kakeya, H.
    • Journal Title

      Biol. Pharm. Bull.

      Volume: 40 Issue: 9 Pages: 1515-1524

    • DOI

      10.1248/bpb.b17-00339

    • NAID

      130006038773

    • ISSN
      0918-6158, 1347-5215
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K07804, KAKENHI-PLANNED-17H06401

  • [Journal Article] Rolc of NMDA receptor GluN2D subunit in the antideprossant effects of onantiomers of ketamine.2017
    • Author(s)
      Idc S, Ikokubo Y, Mishina M, Hashimoto K, Ikeda K
    • Journal Title

      J Pharmacol Sci

      Volume: 135(3) Issue: 3 Pages: 138-140

    • DOI

      10.1016/j.jphs.2017.11.001

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K15565, KAKENHI-PROJECT-26293347, KAKENHI-PROJECT-16H04676, KAKENHI-PROJECT-17H04324, KAKENHI-PROJECT-16H06276

  • [Journal Article] Metacycloprodigiosin (mcPG) induced cell death selectively in beta-catenin mutated tumor colls.2017
    • Author(s)
      Ikeda H, Shikata Y, Watanapokasin R, Tashiro E, Imoto M
    • Journal Title

      Journal of Antibiotics

      Volume: 70 Pages: 109-112

    • DOI

      10.1038/ja.2016.75

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26350974, KAKENHI-PROJECT-15H03116, KAKENHI-PROJECT-16H06276

  • [Journal Article] Paclitaxel-induced sensory peripheral neuropathy is associated with an ABCB1 single nuclcotide polymorphism and older age in Japanese.2017
    • Author(s)
      Tanabe Y, Shimizu C, Hamada A, Hashimoto K, Ikeda K, Nishizawa D, Hasegawa J, Shimomura A, Ozaki Y, Tamura N, Yamamoto H, Yunokawa M, Yonemori K, Takano T, Kawabata H, Tamura K, Fujiwara Y
    • Journal Title

      Cancer Chemother Pharmacol

      Volume: 79(6) Issue: 6 Pages: 1179-1186

    • DOI

      10.1007/s00280-017-3314-9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08970, KAKENHI-PROJECT-16K15565, KAKENHI-PROJECT-26293347, KAKENHI-PROJECT-17H04324, KAKENHI-PROJECT-26860360, KAKENHI-PROJECT-16H06276

  • [Journal Article] Metacycloprodigiosin (mcPG) induced cell death selectively in β-catenin mutated tumor cells2017
    • Author(s)
      Ikeda H, Shikata Y, Watanapokasin R, Tashiro E, Imoto M.
    • Journal Title

      J. Antibiotics

      Volume: 70 Pages: 109-112

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H03116

  • [Journal Article] Arabilin overcomes resistance to AR-targeted therapy.2017
    • Author(s)
      Fujimaki T, Saito S, and Imoto M.
    • Journal Title

      Journal of Antibiotics

      Volume: 70 Pages: 328-330

    • DOI

      10.1038/ja.2016.162

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H03116, KAKENHI-PROJECT-16H06276

  • [Journal Article] Development of an officient scrcening system to identify novcl bone metabolism-relatcd goncs using the exchangcable gene trap mutagenesis mouse models.2017
    • Author(s)
      Kurogi, S., Sekimoto, T., Funamoto, T., Ota, T., Nakamura, S., Nagai, T., Nakahara, M., Yoshinobu, K., Araki, K., Araki, M. and Chosa, E.
    • Journal Title

      Sci Rop

      Volume: 7 Pages: 40692-40692

    • DOI

      10.1038/srep40692

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26462304, KAKENHI-PROJECT-15K10485, KAKENHI-PROJECT-26462305, KAKENHI-PROJECT-16K07093, KAKENHI-PROJECT-17K11017, KAKENHI-PROJECT-17K19918, KAKENHI-PROJECT-16H06276

  • [Journal Article] High-specd and scalable whole-brain imaging in rodents and primates.2017
    • Author(s)
      Seiriki K, Kasai A, Hashimoto T, Schulze W, Niu M, Yamaguchi S, Nakazawa T, Inoue K, Uezono S, Takada M, Naka Y, Igarashi H, Tanuma M, Wascheck JA, Ago Y, Tanaka KF, Hayata-Takano A, Nagayasu K, Shintani N, Hashimoto R, Kunii Y, Hino M, Matsumoto J, Yabe
    • Journal Title

      Neuron

      Volume: 94 Issue: 6 Pages: 1085-1100

    • DOI

      10.1016/j.neuron.2017.05.017

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08269, KAKENHI-PROJECT-16KT0193, KAKENHI-PROJECT-17K19454, KAKENHI-PROJECT-17K19488, KAKENHI-INTERNATIONAL-15K21731, KAKENHI-PROJECT-26293020, KAKENHI-ORGANIZER-15H05871, KAKENHI-PUBLICLY-16H01611, KAKENHI-PUBLICLY-16H01621, KAKENHI-PUBLICLY-17H05565, KAKENHI-PUBLICLY-17H05567, KAKENHI-PUBLICLY-17H06030, KAKENHI-PUBLICLY-17H06062, KAKENHI-PLANNED-25117005, KAKENHI-PROJECT-16H02454, KAKENHI-PROJECT-15H03123, KAKENHI-PROJECT-16H05375, KAKENHI-PROJECT-16K15125, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-16H06297, KAKENHI-PROJECT-15H04645, KAKENHI-PROJECT-17H03989, KAKENHI-PROJECT-17H05054

  • [Journal Article] One-step Transformation of Trichloroacetamide into Isonitrile2017
    • Author(s)
      Adachi, M.; Miyasaka, T.; Hashimoto, H.; Nishikawa, T.
    • Journal Title

      Org. Lett.

      Volume: 19 Pages: 380-383

    • DOI

      10.1021/acs.orglett.6b03583

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K12743, KAKENHI-PROJECT-15K07410

  • [Journal Article] Simple generation of hairless mice for in vivo imaging.2017
    • Author(s)
      Hoshino Y, Mizuno S, Kato K, Mizuno-Iijima S, Tanimoto Y, Ishida M, Kajiwara N, Sakasai T, Miwa Y, Takahashi S, Yagami KI, Sugiyama F
    • Journal Title

      Experimental Animals

      Volume: 66(4) Issue: 4 Pages: 437-445

    • DOI

      10.1538/expanim.17-0049

    • NAID

      130006187194

    • ISSN
      0007-5124, 1341-1357, 1881-7122
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-15H05935, KAKENHI-PROJECT-26221004, KAKENHI-PROJECT-15H04281, KAKENHI-PROJECT-16K14589, KAKENHI-PROJECT-16H06276, KAKENHI-PUBLICLY-16H01630

  • [Journal Article] Antarlides F-H, new members of the antarlide family produced by Streptomyces sp. BB47.2017
    • Author(s)
      Saito S, Fujimaki T, Panbangred W, Sawa R, Igarashi Y, Imoto M
    • Journal Title

      Journal of Antibiotics

      Volume: 印刷中 Pages: 595-600

    • DOI

      10.1038/ja.2017.6

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H03116, KAKENHI-PROJECT-16H06276

  • [Journal Article] Decreased cohesin in the brain leads to defective synapse devclopmont and anxicty-related behavior.2017
    • Author(s)
      Fujita Y, Masuda K, Bando M, Nakato R, Katou Y, Tanaka T, Nakayama M, Takao K, Miyakawa T, Tanaka T, Ago Y, Hashimoto H, Shirahige K, Yamashita T
    • Journal Title

      The Journal of Experiment Medicine

      Volume: 印刷中 Issue: 5 Pages: 1431-1452

    • DOI

      10.1084/jem.20161517

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PUBLICLY-15H01288, KAKENHI-PUBLICLY-15H01347, KAKENHI-ORGANIZER-15H05970, KAKENHI-PLANNED-15H05976, KAKENHI-PROJECT-15H02369, KAKENHI-PROJECT-16H04718, KAKENHI-PROJECT-26670122, KAKENHI-INTERNATIONAL-15K21761, KAKENHI-PROJECT-16K01946, KAKENHI-PROJECT-26293020, KAKENHI-PUBLICLY-16H01270, KAKENHI-PUBLICLY-17H06051, KAKENHI-PROJECT-17H06178, KAKENHI-PROJECT-16K18364, KAKENHI-PROJECT-16H06276

  • [Journal Article] Decreased cohesin in the brain leads to defective synapse development and anxiety-related behavior.2017
    • Author(s)
      Fujita Y, Masuda K, Bando M, Nakato R, Katou Y, Tanaka T, Nakayama M, Takao K, Miyakawa T, Tanaka T, Ago Y, Hashimoto H, Shirahige K, Yamashita T
    • Journal Title

      The Journal of Experiment Medicine

      Volume: 214 Issue: 5 Pages: 1431-1452

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Journal Article] Gut microbiota promotes obesity-associated liver cancer throug PGE2-mediated suppression of antitumor immunity2017
    • Author(s)
      Loo TM, Kamachi F, Watanabe Y, Yoshimoto S, Kanda H, Arai Y, Nakajima-Takagi Y, Iwama A, Koga T, Sugimoto Y, Ozawa T, Nakamura M, Kumagai M, Watashi K, Taketo MM, Aoki T, Narumiya S, Oshima M, Arita M, Hara E, Ohtani N
    • Journal Title

      Cancer Discovery

      Volume: 7 Pages: 522-538

    • DOI

      10.1158/2159-8290.cd-16-0932

    • Description
      Epub ahead of print
    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05905, KAKENHI-PROJECT-26250028, KAKENHI-PROJECT-14J06998, KAKENHI-PROJECT-15K12709, KAKENHI-PROJECT-15K19032, KAKENHI-PROJECT-26670030, KAKENHI-PROJECT-15K19031, KAKENHI-PROJECT-16H06276, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05898, KAKENHI-PROJECT-17H01531, KAKENHI-PROJECT-15H04648, KAKENHI-PROJECT-17H03990, KAKENHI-PROJECT-26460565, KAKENHI-PROJECT-16H04699

  • [Journal Article] Mitochondrial uncoupler exerts a synthetic lethal effect against beta-catenin mutant tumor cells.2017
    • Author(s)
      Shikata Y, Kiga M, Futamura Y, Aono H, Inoue H, Kawada M, Osada H, and Imoto M.
    • Journal Title

      Cancer Science

      Volume: 108 Pages: 772-784

    • DOI

      10.1111/cas.13172

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H03116, KAKENHI-PROJECT-15K06888, KAKENHI-PROJECT-16H06276

  • [Journal Article] Protein kinase A inhibition facilitates the antitumor activity of xanthohumol, a valosin-containing protein inhibitor.2017
    • Author(s)
      Shikata Y, Yoshimaru T, Komatsu M, Katoh H, Sato R, Kanagaki S, Okazaki Y, Toyokuni S, Tashiro E, Ishikawa S, Katagiri T, Imoto M.
    • Journal Title

      Cancer Science

      Volume: 108 Pages: 785-794

    • DOI

      10.1111/cas.13175

    • NAID

      120006535004

    • Description
      Epub ahead of print
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-24108008, KAKENHI-PROJECT-26350974, KAKENHI-PROJECT-26461948, KAKENHI-PROJECT-15K08398, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H02481, KAKENHI-PROJECT-15H03116

  • [Journal Article] The mechanics clarifying counterclockwise rotation in most IVF eggs in mice.2017
    • Author(s)
      Ishimoto K, Ikawa M, Okabe M.
    • Journal Title

      Sci Rep.

      Volume: 7 Pages: 43456-43456

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Journal Article] Involvement of the MEK/ERK pathway in EGF-induced E-cadherin down-regulation2016
    • Author(s)
      Tashiro E, Henmi S, Odake H, Ino S, Imoto M
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 477 Pages: 801-806

    • DOI

      10.1016/j.bbrc.2016.06.138

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26350974

  • [Journal Article] Antarlides, A new-type of Androgen Receptor (AR) Antagonist, that overcomes resistance to AR-targeted Therapy.2016
    • Author(s)
      Saito S, Fujimaki T, Panbangred W, Igarashi Y, Imoto M.
    • Journal Title

      Angewandte Chemie Int. Ed

      Volume: 55 Pages: 2718-2732

    • DOI

      10.1002/anie.201510079

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23102006, KAKENHI-PROJECT-15H03116

  • [Journal Article] Claspin recruits Cdc7 kinase for initiation of DNA replication in human cells.2016
    • Author(s)
      Yang CC, Suzuki M, Yamakawa S, Uno S, Ishii A, Yamazaki S, Fukatsu R, Fujisawa R, Sakimura K, Tsurimoto T, Masai H
    • Journal Title

      Nat Commun.

      Volume: 7 Pages: 12135-12135

    • DOI

      10.1038/ncomms12135

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H04650, KAKENHI-PROJECT-16H04743, KAKENHI-PROJECT-25440011, KAKENHI-PROJECT-16K07456, KAKENHI-PROJECT-16K14675, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-25000015, KAKENHI-PROJECT-26251004

  • [Journal Article] Ulbactins F and G, Polycyclic Thiazoline Derivatives with Tumor Cell Migration Inhibitory Activity from Brevibacillus sp.2016
    • Author(s)
      Igarashi Y, Asano D, Sawamura M, In Y, Ishida T, Imoto M.
    • Journal Title

      Org Lett.

      Volume: 18 Pages: 1658-1661

    • DOI

      10.1021/acs.orglett.6b00531

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Journal Article] The jasmonate-responsive ​GTR1 transporter is required for gibberellin-mediated stamen development in Arabidopsis.2016
    • Author(s)
      H. Saito, T. Oikawa, S. Hamamoto, Y. Ishimaru, T. Utsumi, J. Chen, M. Kanamori, Y. Sasaki-Sekimoto, M. Shimojima, S. Masuda, Y. Kamiya, M. Seo, N. Uozumi, M. Ueda, H. Ohta, A
    • Journal Title

      Plant Cell Physiol.

      Volume: 6 Pages: 1-11

    • DOI

      10.1038/ncomms7095

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-ORGANIZER-23102001, KAKENHI-PLANNED-23102012, KAKENHI-PUBLICLY-24102504, KAKENHI-PROJECT-24580135, KAKENHI-PUBLICLY-25119725, KAKENHI-PROJECT-15K18678, KAKENHI-PROJECT-15K18687, KAKENHI-PROJECT-15J02984, KAKENHI-PROJECT-26282207, KAKENHI-PROJECT-25292055

  • [Journal Article] GNASR201H and KrasG12D cooperate to promote murine pancreatic tumorigenesis recapitulating human intraductal papillary mucinous neoplasm2016
    • Author(s)
      Taki, K., Ohmuraya, M., Tanji, E., Komatsu, H., Hashimoto, D., Semba, K., Araki, K., Kawaguchi, Y., Baba, H. and Furukawa, T.
    • Journal Title

      Oncogene.

      Volume: in press Pages: 2407-2412

    • DOI

      10.1038/onc.2015.294

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-221S0001, KAKENHI-PLANNED-26110003, KAKENHI-PUBLICLY-26111516, KAKENHI-PROJECT-25640052, KAKENHI-PROJECT-25670653

  • [Journal Article] Ionic basis for membrane potential resonance in neurons of the inferiorolive.2016
    • Author(s)
      Matsumoto-Makidono Y, Nakayama H, Yamasaki M, Miyazaki T, Kobayashi K, Watanabe M, Kano M, Sakimura K, Hashimoto K.
    • Journal Title

      Cell Rep

      Volume: 16 Pages: 994-1004

    • DOI

      10.1016/j.celrep.2016.06.053

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PUBLICLY-16H01615, KAKENHI-PLANNED-25117006, KAKENHI-PLANNED-26112002, KAKENHI-PROJECT-24220007, KAKENHI-PROJECT-16H04650, KAKENHI-PROJECT-26460250, KAKENHI-PROJECT-26460251, KAKENHI-PROJECT-15K18342, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H06280, KAKENHI-PROJECT-25000015

  • [Journal Article] Synthesis of firefly luciferin analogues and evaluation of the luminescent properties.2016
    • Author(s)
      Ioka　S, Saitoh T, Iwano S, Suzuki K, Maki S.A., Miyawaki A, Imoto M, and Nishiyama S.
    • Journal Title

      Chem. Eur. J.

      Volume: 未定

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H03116

  • [Journal Article] microRNA-203 suppresses invasion and epithelial-mesenchymal transition induction via targeting NUAK1 in head and neck cancer.2016
    • Author(s)
      Obayashi, M., Yoshida, M., Tsunematsu, T., Ogawa, I., Sasahira, T., Kuniyasu, H., Imoto, I., Abiko, Y., Xu, D., Fukunaga, S., Tahara, H., Kudo, Y., Nagao, T., Takata, T.
    • Journal Title

      Oncotarget.

      Volume: 6972 Pages: 8223-39

    • DOI

      10.18632/oncotarget.6972

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15740, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-26640091, KAKENHI-PROJECT-26290047, KAKENHI-PROJECT-26293304, KAKENHI-PROJECT-26310106, KAKENHI-PROJECT-16H05164

  • [Journal Article] Chemistry and biology of the compounds that modulate cell migration2016
    • Author(s)
      Tashiro E, Imoto M.
    • Journal Title

      J Ind Microbiol Biotechnol.

      Volume: 43 Pages: 213-9

    • DOI

      10.1007/s10295-015-1654-1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26350974

  • [Journal Article] Screening and target identification of bioactive compounds that modulate cell migration and autophagy2016
    • Author(s)
      Tashiro E and Imoto M
    • Journal Title

      Bioorganic & Medicinal Chemistry

      Volume: 24 Pages: 3283-3290

    • DOI

      10.1016/j.bmc.2016.04.014

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26350974

  • [Journal Article] The A Allele at rs13419896 of EPAS1 Is Associated with Enhanced Expression and Poor Prognosis for Non-Small Cell Lung Cancer2015
    • Author(s)
      Andika C. Putra, Hidetaka Eguchi, Kian Leong Lee, Yuko Yamane, Ewita Gustine, Takeshi Isobe, Masahiko Nishiyama, Keiko Hiyama, Lorenz Poellinger, Keiji Tanimoto*.
    • Journal Title

      PLoS One.

      Volume: 10 Pages: 0134496-0134496

    • DOI

      10.1371/journal.pone.0134496

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K11252, KAKENHI-PROJECT-25461159, KAKENHI-PROJECT-221S0001

  • [Journal Article] Low FOXA1 expression predicts good response to neo-adjuvant chemotherapy resulting in good outcomes for luminal HER2-negative breast cancer cases2015
    • Author(s)
      Horimoto, Y., Arakawa A., Harada-Shoji N., Sonoue H., Yoshida Y., Himuro T., Igari F., Tokuda E., Mamat O., Tanabe M., Hino O. and Saito M.
    • Journal Title

      Br J Cancer

      Volume: 112

    • DOI

      10.1038/bjc.2014.595

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] Mechanism for increased hepatic glycerol synthesis in the citrin/mitochondrial glycerol-3-phosphate dehydrogenase double-knockout mouse : Urine glycerol and glycerol 3-phosphate as potential diagnostic markers of human citrin deficiency.2015
    • Author(s)
      Moriyama M, Fujimoto Y, Rikimaru S, Ushikai M, Kuroda E, Kawabe K, Takano K, Asakawa A, Inui A, Eto K, Kadowaki T, …, Kure S, Mitsubuchi H, Endo F, Horiuchi M, Nakamura Y, Yamamura K, Saheki T
    • Journal Title

      BBA Molecular Basis of Disease

      Volume: 印刷中 Pages: 1787-1795

    • DOI

      10.1016/j.bbadis.2015.04.023

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24590892, KAKENHI-PROJECT-15K07768, KAKENHI-PROJECT-15K09595, KAKENHI-PROJECT-26450447, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-15J12259, KAKENHI-PROJECT-25461275, KAKENHI-PROJECT-26850209, KAKENHI-PROJECT-26000012

  • [Journal Article] Urethral toxicity after LDR brachytherapy : experience in Japan2015
    • Author(s)
      Tanaka, N., Asakawa I., Hasegawa M. and Fujimoto K.
    • Journal Title

      Brachytherapy

      Volume: 14

    • DOI

      10.1016/j.brachy.2014.09.009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] Associations between polymorphisms of interleukin-6 and related cytokine genes and serum liver damage markers : a cross-sectional study in the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study2015
    • Author(s)
      Sugimoto Y, Wakai K, Nakagawa H, Suma S, Sasakabe T, Sakamoto T, Takashima N, Suzuki S, Ogawa S, Ohnaka K, Kuriyama N, Arisawa K, Mikami H, Kubo M, Hosono S, Hamajima N, Tanaka H; J-MICC Study Group.
    • Journal Title

      Gene

      Volume: 557 Pages: 158-162

    • DOI

      10.1016/j.gene.2014.12.025

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26460757, KAKENHI-PROJECT-221S0001

  • [Journal Article] B-RAF mutation and accumulated gene methylation in aberrant crypt foci (ACF), sessile serrated adenoma/polyp (SSA/P) and cancer in SSA/P.2015
    • Author(s)
      Inoue A, Okamoto K, Fujino Y, Nakagawa T, Muguruma N, Sannomiya K, Mitsui Y, Takaoka T, Kitamura S, Miyamoto H, Okahisa T, Fujimori T, Imoto I, Takayama T
    • Journal Title

      Br J Cancer

      Volume: 112 Pages: 403-412

    • DOI

      10.1038/bjc.2014.545

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26293176, KAKENHI-PROJECT-26293304, KAKENHI-PROJECT-221S0001

  • [Journal Article] Region-specific regulation of cell proliferation by FGF receptor signaling during the Wolffian duct development.2015
    • Author(s)
      Mika Okazawa, Aki Murashima, Masayo Harada, Naomi Nakagata, Masafumi Noguchi, Mitsuru Morimoto, Tadashi Kimura, David M. Ornitz, Gen Yamada
    • Journal Title

      Dev Biol.

      Volume: 1;400(1) Pages: 139-147

    • DOI

      10.1016/j.ydbio.2015.01.023

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25860771, KAKENHI-PROJECT-15K15403, KAKENHI-PROJECT-15K19013, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-15H04300

  • [Journal Article] Apoptosis induction associated with the ER stress response through up-regulation of JNK in HeLa cells by gambogic acid2015
    • Author(s)
      Krajarng A, Imoto M, Tashiro E, Fujimaki T, Shinjo S, Watanapokasin R.
    • Journal Title

      BMC Complement Altern Med.

      Volume: 15 Pages: 26-26

    • DOI

      10.1186/s12906-015-0544-4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26350974

  • [Journal Article] SMK-17, a MEK1/2-specific inhibitor, selectively induces apoptosis in β-catenin-mutated tumors2015
    • Author(s)
      Kiga M, Nakayama A, Shikata Y, Sasazawa Y, Murakami R, Nakanishi T, Tashiro E, Imoto M.
    • Journal Title

      Sci. Rep.

      Volume: 5 Pages: 8155-8155

    • DOI

      10.1038/srep08155

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-23102006, KAKENHI-PROJECT-26350974, KAKENHI-PROJECT-26750373, KAKENHI-PROJECT-221S0001

  • [Journal Article] Chemical biology of compounds obtained from screening using disease models2015
    • Author(s)
      Tashiro E, Imoto M.
    • Journal Title

      Arch Pharm Res.

      Volume: 38 Pages: 1651-60

    • DOI

      10.1007/s12272-015-0633-4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26350974

  • [Journal Article] No association between Helicobacter pylori infection and diabetes mellitus among a general Japanese population: a cross-sectional study2015
    • Author(s)
      Tamura T, Morita E, Kawai S, Sasakabe T, Sugimoto Y, Fukuda N, Suma S, Nakagawa H, Okada R, Hishida A, Naito M, Hamajima N, Wakai K
    • Journal Title

      Springerplus

      Volume: 4 Pages: 602-602

    • DOI

      10.1186/s40064-015-1371-2

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] Reducing DNA methylation suppresses colon carcinogenesis by inducing tumor cell differentiation.2015
    • Author(s)
      Hatano Y, Semi K, Hashimoto K, Lee MS, Hirata A, Tomita H, Kuno T, Takamatsu M, Aoki K, Taketo MM, Kim YJ, Hara A, Yamada Y.
    • Journal Title

      Carcinogenesis.

      Volume: 36 Pages: 719-29

    • DOI

      10.1093/carcin/bgv060

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-15H04721, KAKENHI-PROJECT-26830069, KAKENHI-PROJECT-24680091

  • [Journal Article] Murine Herc6 plays a critical role in protein ISGylation in vivo and has an ISGylation independent function in seminal vesicles.2015
    • Author(s)
      Arimoto KI, Hishiki T, Kiyonari H, Abe T, Cheng C, Yan M, Fan JB, Futakuchi M, Tsuda H, Murakami Y, Suzuki H, Zhang DE, Shimotohno K
    • Journal Title

      J Interferon Cytokine Res

      Volume: 35 Pages: 351-358

    • DOI

      10.1089/jir.2014.0113

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-22114004, KAKENHI-PROJECT-24501319, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-15K06837, KAKENHI-PROJECT-15K19109

  • [Journal Article] Everyday clinical practice in IgG4-related dacryoadenitis and/or sialadenitis: results from the SMART database.2015
    • Author(s)
      Yamamoto M, Yajima H, Takahashi H, Yokoyama Y, Ishigami K, Shimizu Y, Tabeya T, Suzuki C, Naishiro Y, Takano KI, Yamashita K, Hashimoto M, Keira Y, Honda S, Abe T, Suzuki Y, Mukai M,Himi T, Hasegawa T, Imai K, Shinomura Y
    • Journal Title

      Modern Rheumatology

      Volume: 27 Pages: 199-204

    • DOI

      10.3109/14397595.2014.950036

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25861575, KAKENHI-PROJECT-15K10818, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-26640101

  • [Journal Article] Evaluation of drug toxicity profiles based on the phenotypes of ascidian Ciona intestinalis.2015
    • Author(s)
      Mizotani Y, Itoh S, Hotta K, Tashiro E, Oka K, Imoto M.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 463 Pages: 656-60

    • DOI

      10.1016/j.bbrc.2015.05.119

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26350974, KAKENHI-PLANNED-23102006, KAKENHI-PROJECT-15H03116

  • [Journal Article] Apoptosis induction associated with the ER stress response through up-regulation of JNK in HeLa cells by gambogic acid2015
    • Author(s)
      Krajamg A, Imoto M, Tashiro E, Fujimaki T, Shinjo S, and Watanapokasin R
    • Journal Title

      BMC Complementary & Alternative Medicine

      Volume: 15 Pages: 26-26

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26350974

  • [Journal Article] Syndecan-1 responsive microRNA-126 and 149 regulate cell proliferation in prostate cancer2015
    • Author(s)
      Tomomi Fujii, Keiji Shimada, Yoshihiro Tatsumi, Kiyohide Fujimoto, Noboru Konishi
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 456 Pages: 183-189

    • DOI

      10.1016/j.bbrc.2014.11.056

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26462424, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-26293079

  • [Journal Article] Integrated analysis of whole genome and transcriptome sequencing reveals diverse transcriptomic aberrations driven by somatic genomic changes in liver cancers.2015
    • Author(s)
      Shiraishi Y, Fujimoto A, Furuta M, Chayama K, Tsunoda T, Miyano S, and Nakagawa H, 他
    • Journal Title

      PLoS One.

      Volume: 9

    • DOI

      10.1371/journal.pone.0114263

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-22134008, KAKENHI-PUBLICLY-25134717, KAKENHI-PROJECT-25670375, KAKENHI-PROJECT-26430196, KAKENHI-PROJECT-26670383, KAKENHI-PROJECT-221S0001

  • [Journal Article] 5-lipoxygenase and cysteinyl leukotriene receptor 1 regulate epidermal growth factor-induced cell migration through Tiam1 upregulation and Rac1 activation2014
    • Author(s)
      Magi S, Takemoto Y, Kobayashi H, Kasamatsu M, Akita T, Tanaka A, Takano K, Tashiro E, Igarashi Y, Imoto M.
    • Journal Title

      Cancer Sci

      Volume: 105 Pages: 290-296

    • DOI

      10.1111/cas.12340

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-23102006, KAKENHI-PROJECT-25560419, KAKENHI-PROJECT-26350974, KAKENHI-PROJECT-221S0001

  • [Journal Article] Nadir PSA level and time to nadir PSA are prognostic factors in patients with metastatic prostate cancer2014
    • Author(s)
      Tomioka, A., Tanaka N., Yoshikawa M., Miyake M., Anai S., Chihara Y., Okajima E., Hirayama A., Hirao Y. and Fujimoto K.
    • Journal Title

      BMC Urol

      Volume: 14

    • DOI

      10.1186/1471-2490-14-33

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] Proteomic Analysis of Proteins Related to Prognosis of Lung Adenocarcinoma.2014
    • Author(s)
      Okayama A, Miyagi Y, Oshita F, Nishi M, Nakamura Y, Nagashima Y, Akimoto K, Ryo A, Hirano H.
    • Journal Title

      J Proteome Res

      Volume: 13 Issue: 11 Pages: 4686-464

    • DOI

      10.1021/pr4012969

    • NAID

      130005454677

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26460456, KAKENHI-PROJECT-221S0001

  • [Journal Article] Multicenter phase Ⅱ study of mogamulizumab (KW-0761), a defucosylated anti-cc chemokine receptor 4 antibody, in patients with relapsed peripheral T-cell lymphoma and cutaneous T-cell lymphoma.2014
    • Author(s)
      Ogura M, Ishida T, Hatake K, Taniwaki M, Ando K, Tobinai K, Fujimoto K, Yamamoto K, Miyamoto T, Uike N, Tanimoto M, Tsukasaki K, Ishizawa K, Suzumiya J, Inagaki H, Tamura K, Akinaga S, Tomonaga M, Ueda R.
    • Journal Title

      J Clin Oncol,

      Volume: 32 Pages: 1157-1163

    • DOI

      10.1200/jco.2013.52.0924

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390254, KAKENHI-PROJECT-23501318, KAKENHI-PROJECT-24590677, KAKENHI-PROJECT-221S0001

  • [Journal Article] Photodynamic diagnosis of shed prostate cancer cells in voided urine treated with 5-aminolevulinic acid2014
    • Author(s)
      Nakai Y, Anai S, Kuwada M, Miyake M, Chihara Y, Tanaka N, Hirayama A, Yoshida K, Hirao Y, Fujimoto K.
    • Journal Title

      BMC Urol

      Volume: 3

    • DOI

      10.1186/1471-2490-14-59

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25861445, KAKENHI-PROJECT-221S0001

  • [Journal Article] Rat strain differences in levels and effects of chronic inflammation due to intratracheal instillation of quartz on lung tumorigenesis induced by DHPN2014
    • Author(s)
      Nakano Y, Yokohira M, Hashimoto N, Yamakawa K, Kishi S, Ninomiya F, Kanie S, Saoo K, Imaida K
    • Journal Title

      Exp. Toxicol. Pathol

      Volume: 66

    • DOI

      10.1016/j.etp.2014.06.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] Disruption of actin-binding domain-containing dystonin protein causes dystonia musculorum in mice.2014
    • Author(s)
      Horie, M., Watanabe, K., Bepari, A. K., Nashimoto, J., Araki, K., Sano, H., Chiken, S., Nambu, A., Ono, K., Ikenaka, K., Kakita, A., Yamamura, K. and Takebayashi, H.
    • Journal Title

      Eur. J. Neurocsi

      Volume: 40 Pages: 3458-3471

    • DOI

      10.1111/ejn.12711

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-23310135, KAKENHI-PROJECT-23590237, KAKENHI-PROJECT-24700351, KAKENHI-PLANNED-25117007, KAKENHI-PROJECT-25351002, KAKENHI-PROJECT-26430021, KAKENHI-PROJECT-221S0001

  • [Journal Article] Xanthohumol suppresses oestrogen-signalling in breast cancer through the inhibition of BIG3-PHB2 interactions2014
    • Author(s)
      T. Yoshimaru, M. Komatsu, E. Tashiro, M. Imoto, H. Osada, Y. Miyoshi, J. Honda, M. Sasa, T. Katagiri
    • Journal Title

      Scientific reports

      Volume: 4 Pages: 7355-7355

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-ORGANIZER-23102001

  • [Journal Article] Use of alpha-1 adrenoceptor antagonists in patients who underwent low-dose-rate brachytherapy for prostate cancer-a randomized controlled trial of silodosin versus naftopidil2014
    • Author(s)
      Tanaka, N., Torimoto K., Asakawa I., Miyake M., Anai S., Hirayama A., Hasegawa M., Konishi N. and Fujimoto K.
    • Journal Title

      Radiat Oncol

      Volume: 9

    • DOI

      10.1186/s13014-014-0302-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] Generation and analysis of serine protease inhibitor Kazal type 3-cre driver mice2014
    • Author(s)
      Sakata, K., Ohmuraya, M., Araki, K., Suzuki, C., Ida, S., Hashimoto, D., Wang, J., Uchiyama, Y., Baba, H. and Yamamura, K.
    • Journal Title

      Exp. Anim.

      Volume: 63

    • NAID

      130003391605

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] Proposed salvage treatment strategy for biochemical failure after radical prostatectomy in patients with prostate cancer : a retrospective study2014
    • Author(s)
      Miyake, M., Tanaka N., Asakawa I., Morizawa Y., Anai S., Torimoto K., Aoki K., Yoneda T., Hasegawa M., Konishi N. and Fujimoto K.
    • Journal Title

      Radiat Oncol

      Volume: 9

    • DOI

      10.1186/1748-717x-9-208

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] Chemical genomic-based pathway analyses for epidermal growth factor-mediated signaling in migrating cancer cell2014
    • Author(s)
      Magi S, Saeki Y, Kasamatsu M, Tashiro E, Imoto M.
    • Journal Title

      PLoS One

      Volume: 9

    • DOI

      10.1371/journal.pone.0096776

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-23102006, KAKENHI-PROJECT-26350974

  • [Journal Article] Identification of licopyranocoumarin and glycyrurol from herbal medicines as neuroprotective compounds for Parkinson’s disease2014
    • Author(s)
      Fujimaki T, Saiki S, Tashiro E, Yamada D, Kitagawa M, Hattori N and Imoto M.
    • Journal Title

      PLoS One

      Volume: 9

    • DOI

      10.1371/journal.pone.0100395

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-23102006, KAKENHI-PROJECT-26350974

  • [Journal Article] Hepatoid giant cell tumor of tendon sheath-A rare morphologic variant case report2014
    • Author(s)
      Yoshimoto, T., Motoi, N., Kanda, H., Tanizawa, T., Shimoji, T., Matsumoto, S., Mukai, H., Ishikawa, Y., Machinami, R.
    • Journal Title

      Pathology Res. Practice

      Volume: 14

    • DOI

      10.1016/j.prp.2014.05.012

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] The biochemical recurrence-free rate in patients who underwent prostate low-dose-rate brachytherapy, using two different definitions.2014
    • Author(s)
      Tanaka N, Asakawa I, Katayama E, Hirayama A, Hasegawa M, Konishi N, Fujimoto K
    • Journal Title

      Radiation Oncology

      Volume: 9(1) Pages: 107-107

    • DOI

      10.1186/1748-717x-9-107

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23390304, KAKENHI-PROJECT-26293079, KAKENHI-PROJECT-221S0001

  • [Journal Article] Association of EPAS1 gene rs4953354 polymorphism with susceptibility to lung adenocarcinoma in female Japanese non-smokers2014
    • Author(s)
      Iwamoto, S., Tanimoto K., Nishio Y., Putra A.C., Fuchita H., Ohe M., Sutani A., Kuraki T., Hiyama K., Murakami I., Eguchi H. and Isobe T.
    • Journal Title

      J Thorac Oncol

      Volume: 9

    • DOI

      10.1097/jto.0000000000000309

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] Xanthohumol suppresses oestrogen-signalling in breast cancer through the specific inhibition of BIG3-PHB2 interactions.2014
    • Author(s)
      Yoshimaru T, Komatsu M, Tashiro E, Imoto M, Osada H, Miyoshi M, Honda J, Sasa M, and Katagiri T
    • Journal Title

      Sci Rep

      Volume: 4 Pages: 7335-7335

    • DOI

      10.1038/srep07355

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-23102006, KAKENHI-PUBLICLY-25134712, KAKENHI-PROJECT-25293079, KAKENHI-PROJECT-26350974, KAKENHI-PROJECT-26461948, KAKENHI-PROJECT-26860212, KAKENHI-PROJECT-221S0001

  • [Journal Article] Lung adenocarcinoma subtypes definable by lung development-related miRNA expression profiles in association with clinicopathologic features.2014
    • Author(s)
      Arima C, Kajino T, Tamada Y, Imoto S, ShimadaY, Nakatochi, M, Suzuki M, Isomura H, Yatabe Y, Yamaguchi T, Yanagisawa K, Miyano S, Takahashi T
    • Journal Title

      Carcinogenesis

      Volume: 35 Pages: 2224-2231

    • DOI

      10.1093/carcin/bgu127

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-22134005, KAKENHI-PROJECT-25293191, KAKENHI-PROJECT-25640076, KAKENHI-PROJECT-26290051, KAKENHI-PROJECT-26670625, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-25250017

  • [Journal Article] 5-Lipoxygenase and CysLT1 regulate EGF-induced cell migration through Tiam1 upregulation and Rac1 activation2014
    • Author(s)
      Magi S, Takemoto Y, Kobayashi H, Kasamatsu M, Akita T, Tanaka A, Takano K, Tashiro E, Igarashi Y, Imoto M
    • Journal Title

      Cancer Science

      Volume: 105 Pages: 290-296

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Journal Article] Novel isoflavone glucosides in Groundnut (Apios americana Medik) and their antiandrogenic activities2013
    • Author(s)
      Ichige M, Fukuda E, Miida S, Hattan J, Misawa N, Saito S, Fujimaki T, Imoto M. Shindo K
    • Journal Title

      J. Agric. Food Chem

      Volume: 61 Pages: 2183-2187

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Journal Article] A Comparative Analysis of the Expression Patterns of UPR-Target Genes caused by UPR-inducing Compounds.2013
    • Author(s)
      Shinjo S, Mizotani Y, Tashiro E, Imoto M.
    • Journal Title

      Biosci. Biotechnol. Biochem.

      Volume: 77 Pages: 729-735

    • NAID

      10031170710

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Journal Article] HCV NS3 protease enhances liver fibrosis via binding to and activating TGF-β type I receptor2013
    • Author(s)
      Sakata K, Eda S, Lee E, Hara M, Imoto M, Kojima S.
    • Journal Title

      Scientific Reports.

      Volume: 3 Pages: 3243-3243

    • DOI

      10.1038/srep03243

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23102006, KAKENHI-PROJECT-23390202, KAKENHI-PLANNED-24115003, KAKENHI-PROJECT-24390111, KAKENHI-PROJECT-25560419, KAKENHI-PROJECT-221S0001

  • [Journal Article] Early-onset diffuse gastric cancer associated with a de novo large genomic deletion of CDH1 gene.2013
    • Author(s)
      Sugimoto S, Yamada H, Takahashi M, Sugimura H et al.
    • Journal Title

      Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association

      Volume: -

    • DOI

      10.1007/s10120-013-0278-2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] A Comparative Analysis of the Expression Patterns of UPR-Target Genes caused by UPR-inducing Compounds2013
    • Author(s)
      Shinjo S, Mizotani Y, Tashiro E, Imoto M
    • Journal Title

      Biosci. Biotechnol. Biochem.

      Volume: 77 Pages: 729-735

    • NAID

      10031170710

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Journal Article] Novel derivatives of aclacinomycin A block cancer cell migration through inhibition of farnesyl transferase2013
    • Author(s)
      Magi S, Shitara T, Takemoto Y, Sawada M, Kitagawa M, Tashiro E. Takahashi Y, Imoto M
    • Journal Title

      J. Antibiot.

      Volume: 66 Pages: 165-170

    • NAID

      10031163117

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Journal Article] Novel isoflavone glucosides in Groundnut (Apios americana Medik) and their antiandrogenic activities2013
    • Author(s)
      Ichige M, Fukuda E,Miida S, Hattan J, Misawa N, Saito S, Fujimaki T, Imoto M. Shindo K
    • Journal Title

      J. Agric. Food Chem

      Volume: 61 Pages: 2183-2187

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] A Comparative Analysis of the Expression Patterns of UPR-Target Genes caused by UPR-inducing Compounds2013
    • Author(s)
      Shinjo S, Mizotani Y,Tashiro E, Imoto M
    • Journal Title

      Biosci. Biotechnol. Biochem

      Volume: 77 Pages: 729-735

    • NAID

      10031170710

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome.2013
    • Author(s)
      Yoshimoto, S.
    • Journal Title

      Nature

      Volume: 499 Pages: 97-101

    • DOI

      10.1038/nature12347

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23112101, KAKENHI-PROJECT-23300343, KAKENHI-PROJECT-23300352, KAKENHI-PROJECT-24650625, KAKENHI-PROJECT-25293080, KAKENHI-PROJECT-221S0001

  • [Journal Article] Establishment of a new detection system for the dimerization of IRE1α with BiFC method.2013
    • Author(s)
      Shinjo S, Tashiro E, Imoto M.
    • Journal Title

      Biosci. Biotechnol. Biochem

      Volume: 77 Pages: 1333-1336

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25560419

  • [Journal Article] Establishment of a new detection system for the dimerization of IRE1α with BiFC method2013
    • Author(s)
      Shinjo S, Tashiro E, Imoto M
    • Journal Title

      Biosci. Biotechnol. Biochem.

      Volume: 77 Pages: 1333-1336

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Journal Article] Establishment of a New Detection System for the Dimerization of IRE1&#945; by BiFC Assay2013
    • Author(s)
      Shinjo S, Tashiro E, Imoto M
    • Journal Title

      Biosci. Biotechnol. Biochem.

      Volume: 77 Issue: 6 Pages: 1333-1336

    • DOI

      10.1271/bbb.130107

    • NAID

      10031184708

    • ISSN
      0916-8451, 1347-6947
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Journal Article] Comparative Analysis of the Expression Patterns of UPR-Target Genes Caused by UPR-Inducing Compounds2013
    • Author(s)
      Shinjo S, Mizotani Y, Tashiro E, Imoto M
    • Journal Title

      Biosci. Biotechnol. Biochem.

      Volume: 77 Issue: 4 Pages: 729-735

    • DOI

      10.1271/bbb.120812

    • NAID

      10031170710

    • ISSN
      0916-8451, 1347-6947
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Journal Article] Investigations of motility and fertilization potential in thawed cryopreserved mouse sperm from cold-stored epididymides.2013
    • Author(s)
      Takeo, T., Fukumoto, K., Kondo, T., Haruguchi, Y., Takeshita, Y., Nakamuta, Y., Tsuchiyama, S., Yoshimoto, H., Shimizu, N., Li, MW., Kinchen, K., Vallelunga, J., Lloyd, KC. and Nakagata, N.
    • Journal Title

      Cryobiology.

      Volume: 68(1) Pages: 12-7

    • DOI

      10.1016/j.cryobiol.2013.10.007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] Comparative Analysis of the UPR-Target Genes Expression Patterns induced by UPR-Inducing Compounds2013
    • Author(s)
      S. Shinjo, Y. Mizotani, E. Tashiro, and M. Imoto
    • Journal Title

      Biosci. Biotechnol. Biochem.

      Volume: 77

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Journal Article] Lewis y antigen is expressed in oral squamous cell carcinoma cell lines and tissues, but disappears in the invasive regions leading to the enhanced malignant properties irrespective of sialyl-Lewis x.2013
    • Author(s)
      Hotta H., Hamamura K., Yamashita K,. Shibuya H., Tokuda N., Hashimoto N., Furukawa K., Yamamoto N., Hattori H., Toyokuni S., Ueda M., Furukawa K.
    • Journal Title

      Glycoconj J

      Volume: 30 Pages: 585-597

    • DOI

      10.1007/s10719-012-9458-2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] Establishment of a new detection system for the dimerization of IRE1α using a BiFC assay2013
    • Author(s)
      S. Shinjo, E. Tashiro, and M. Imoto
    • Journal Title

      Biosci. Biotechnol. Biochem.

      Volume: 77

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Journal Article] A Comparative Analysis of the Expression Patterns of UPR-Target Genes caused by UPR-inducing Compounds.2013
    • Author(s)
      Shinjo S, Mizotani Y, Tashiro E, Imoto M.
    • Journal Title

      Biosci. Biotechnol. Biochem

      Volume: 77 Pages: 729-735

    • NAID

      10031170710

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25560419

  • [Journal Article] A Comparative Analysis of the Expression Patterns of UPR-Target Genes caused by UPR-inducing Compounds2013
    • Author(s)
      Shinjo S, Mizotani Y,Tashiro E, Imoto M
    • Journal Title

      Biosci. Biotechnol. Biochem

      Volume: 77 Pages: 729-735

    • NAID

      10031170710

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Journal Article] Novel derivatives of aclacinomycin A block cancer cell migration through inhibition of farnesyl transferase.2013
    • Author(s)
      Shigeyuki Magi, Tetsuo Shitara, Yasushi Takemoto, Masato Sawada, Mitsuhiro Kitagawa, Etsu Tashiro, Yoshikazu Takahashi, Masaya Imoto
    • Journal Title

      J. Antibiot.

      Volume: (掲載決定) Pages: 165-170

    • DOI

      10.1038/ja.2012.108

    • NAID

      10031163117

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-10J04895, KAKENHI-PROJECT-22310140, KAKENHI-PROJECT-22651084, KAKENHI-PLANNED-23102006, KAKENHI-PROJECT-25560419, KAKENHI-PROJECT-221S0001

  • [Journal Article] Establishment of a new detection system for the dimerization of IRE1α with BiFC method.2013
    • Author(s)
      Shinjo S, Tashiro E, Imoto M.
    • Journal Title

      Biosci. Biotechnol. Biochem.

      Volume: 77 Pages: 1333-1336

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Journal Article] Xanthohumol Impairs Autophagosome Maturation through Direct Inhibition of Valosin-Containing Protein2012
    • Author(s)
      Sasazawa Y, Kanagaki S, Tashiro E,Nogawa T, Muroi M, Kondoh Y, Osada H, Imoto M
    • Journal Title

      ACS Chemical Biology

      Volume: 7 Pages: 892-900

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Journal Article] Synthesis and Assignment of the Absolute Configuration of an Indenotryptoline Bisindole Alkaloid2012
    • Author(s)
      Kimura.T, Kanagaki S, Matsui Y, Imoto M, Watanabe T, Shibasaki M
    • Journal Title

      BE-54017. Org. Lett

      Volume: 14 Pages: 4418-4421

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Target identification of bioactive compounds2012
    • Author(s)
      Tashiro E and Imoto M
    • Journal Title

      Bioorg. & Med. Chem.

      Volume: 20 Pages: 1910-1921

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Journal Article] Establishment of a transport system for mouse epididymal sperm at refrigerated temperatures.C2012
    • Author(s)
      Takeo,T., Tsutsumi,A., Omaru,T., Fukumoto,K., Haruguchi,Y., Kondo,T., Nakamuta,Y., Takeshita,Y., Matsunaga,H., Tsuchiyama,S., Sakoh,K., Nakao,S., Yoshimoto,H., Shimizu,N., and Nakagata,N.
    • Journal Title

      Cryobiology.

      Volume: 65 Pages: 163-168

    • DOI

      10.1016/j.cryobiol.2012.06.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] Xanthohumol Impairs Autophagosome Maturation through Direct Inhibition of Valosin-Containing Protein.2012
    • Author(s)
      Sasazawa, Y., Kanagaki, S., Tashiro, E., Nogawa, T., Muroi, M., Kondoh, Y., Osada, H., Imoto, M
    • Journal Title

      ACS Chem. Biol.

      Volume: (in press) Pages: 892-900

    • DOI

      10.1021/cb200492h

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J03075, KAKENHI-PLANNED-20113008, KAKENHI-PROJECT-22310140, KAKENHI-PROJECT-23510287, KAKENHI-PLANNED-23102006

  • [Journal Article] Inostamycin enhanced TRAIL-induced apoptosis through DR5 up-regulation on the cell surface2012
    • Author(s)
      Yamamoto K, Makino M, Watanapokasin R, Tashiro Eand Imoto M
    • Journal Title

      J. Antibiot.

      Volume: 65 Pages: 295-300

    • NAID

      10030797925

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Xanthohumol Impairs Autophagosome Maturation through Direct Inhibition of Valosin-Containing Protein2012
    • Author(s)
      Y.Sasazawa, S.Kanagaki, E.Tashiro, T.Nogawa, M.Muroi, Y.Kondoh, H.Osada, M.Imoto
    • Journal Title

      ACS Chemical Biology

      Volume: (in press)(掲載決定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Journal Article] Identification of Toyocamycin, an agent cytotoxic for multiple myeloma cells, as a potent inhibitor of ER stress-induced XBP1 mRNA splicing2012
    • Author(s)
      Ri M, Tashiro E, Oikawa D, Shinjo S, Tokuda M, Yokouchi Y, Narita T, Masaki A, Ito A, Ding J, Kusumoto S, Ishida T, Komatsu H, Shiotsu Y, Ueda R, Iwawaki T, Imoto M, Iida S
    • Journal Title

      Blood Cancer J.

      Volume: e79

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Journal Article] Target identification of bioactive compounds2012
    • Author(s)
      Tashiro Eand Imoto M.
    • Journal Title

      Bioorg. & Med. Chem

      Volume: 20 Pages: 1910-1921

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Comprehensive Predictions of Target Proteins Based on Protein-Chemical Interaction Using Virtual Screening and Experimental Verifications2012
    • Author(s)
      Kobayashi H, et al Imoto M and Sakakibara Y.
    • Journal Title

      BMC Chem. Biol

      Volume: 12 Pages: 2-2

    • DOI

      10.1186/1472-6769-12-2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140, KAKENHI-PROJECT-23310145

  • [Journal Article] AMF-26, a Novel Inhibitor of the Golgi System, Targeting ADP-ribosylation Factor 1 (Arf1) with Potential for Cancer Therapy.2012
    • Author(s)
      Ohashi Y, Iijima H, Yamaotsu N, Yamazaki K, Sato S, Okamura M, Sugimoto K, Dan S, Hirono S, Yamori T
    • Journal Title

      The Journal of Biological Chemistry

      Volume: 287(6) Pages: 3885-3897

    • DOI

      10.1074/jbc.m111.316125

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22240092, KAKENHI-PROJECT-22590042, KAKENHI-PROJECT-22700929, KAKENHI-PROJECT-221S0001

  • [Journal Article] 1) Inostamycin enhanced TRAIL-induced apoptosis through DR5 up-regulation on the cell surface2012
    • Author(s)
      K. Yamamoto, M. Makino, R. Watanapokasin, E. Tashiro, and M. Imoto
    • Journal Title

      J. Antibiot.

      Volume: 65 Pages: 295-300

    • DOI

      10.1038/ja.2012.21

    • NAID

      10030797925

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23510283, KAKENHI-PLANNED-23102006

  • [Journal Article] A chemical genomic study identifying diversity in cell migration signaling in cancer cells2012
    • Author(s)
      Magi S, Tashiro E and Imoto M
    • Journal Title

      Scientific Reports

      Volume: 2 Pages: 823-823

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Journal Article] Antitumor effects of novel highly hydrophilic and non-ATP-competitive MEK1/2 inhibitor2012
    • Author(s)
      Kiga M, Tanzawa F, Iwasaki S, Inaba F, Fujiwara K, IwadareH, Echigo T, Nakamura Y, Shibata T, Suzuki K, Yasumatsu, I Nakayama A, Sasazawa Y, Tashiro E, Imoto M, S. Kurakata S
    • Journal Title

      SMK-17. Anticancer Drugs.

      Volume: 23 Pages: 119-130

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Non-invasive X-ray micro-computed tomographic evaluation of indomethacin on urethane- induced lung carcinogenesis in mice.2012
    • Author(s)
      Ueno T, Imaida K, Yoshimoto M, Hayakawa T, Takahashi M, Imai T, Yanaka A, Tsuta K, Komiya M, Wakabayashi K and Mutoh M.
    • Journal Title

      Anticancer Res

      Volume: 32(11) Pages: 4773-80

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] Antitumor effects of novel highly hydrophilic and non-ATP-competitive MEK1/2 inhibitor, SMK-172012
    • Author(s)
      Kiga M, Tanzawa F, Iwasaki S, Inaba F, Fujiwara K, Iwadare H, Echigo T, Nakamura Y, Shibata T, Suzuki K, Yasumatsu, I Nakayama A, Sasazawa Y, Tashiro E, Imoto M, S. Kurakata S
    • Journal Title

      Anticancer Drugs

      Volume: 23 Pages: 119-130

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Journal Article] Inostamycin enhanced TRAIL-induced apoptosis through DR5 up-regulation on the cell surface2012
    • Author(s)
      Yamamoto K, Makino M, Watanapokasin R, Tashiro E and Imoto M
    • Journal Title

      J. Antibiot.

      Volume: 65 Pages: 295-300

    • NAID

      10030797925

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Journal Article] Xanthohumol Impairs Autophagosome Maturation through Direct Inhibition of Valosin-Containing Protein2012
    • Author(s)
      Sasazawa Y, Kanagaki S, Tashiro E,Nogawa T, Muroi M, Kondoh Y, Osada H, Imoto M
    • Journal Title

      ACS Chemical Biology

      Volume: 7 Pages: 892-900

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Toxicity of Nicotine by Repeated Intratracheal Instillation to F344 Rats2012
    • Author(s)
      Yokohira M, Nakano Y, Hashimoto N, Yamakawa K, Ninomiya F, Kishi S, Saoo K, Imaida K.
    • Journal Title

      J Toxicol Pathol

      Volume: 25 Issue: 4 Pages: 257-263

    • DOI

      10.1293/tox.25.257

    • NAID

      130002499152

    • ISSN
      0914-9198, 1881-915X
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] Xanthohumol Impairs Autophagosome Maturation through Direct Inhibition of Valosin-Containing Protein2012
    • Author(s)
      Y.Sasazawa, S.Kanagaki, E.Tashiro, T.Nogawa, M.Muroi, Y.Kondoh, H.Osada, M.Imoto
    • Journal Title

      ACS Chemical Biology

      Volume: (in press)(掲載決定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Napyradiomycin A1, an inhibitor of mitochondrial complexes I and II2012
    • Author(s)
      Yamamoto K, Tashiro E, Motohashi K, Seto H and Imoto M.
    • Journal Title

      J. Antibiot

      Volume: 65 Pages: 211-214

    • NAID

      10030641374

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Synthesis and Assignment of the Absolute Configuration of an Indenotryptoline Bisindole Alkaloid2012
    • Author(s)
      Kimura.T, Kanagaki S, Matsui Y, Imoto M, Watanabe T, Shibasaki M.
    • Journal Title

      Org. Lett

      Volume: 14 Pages: 4418-4421

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Journal Article] Napyradiomycin A1, an inhibitor of mitochondrial complexes I and II2012
    • Author(s)
      Yamamoto K, Tashiro E, Motohashi K, Seto H and Imoto M
    • Journal Title

      J. Antibiot

      Volume: 65 Pages: 211-214

    • NAID

      10030641374

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Journal Article] A chemical genomic study identifyingdiversity in cell migration signaling in cancer cells2012
    • Author(s)
      Magi S, Tashiro Eand Imoto M
    • Journal Title

      Scientific Reports

      Volume: 2 Pages: 823-823

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Journal Article] Comprehensive Predictions of Target Proteins Based on Protein-Chemical Interaction Using Virtual Screening and Experimental Verifications2012
    • Author(s)
      Kobayashi H, Harada, H, Nakamura M, FutamuraY, Ito A, Yoshida M, Iemura S, Shin-ya K, Doi T, Takahashi T, Natsume T, Imoto Mand Sakakibara Y
    • Journal Title

      BMC Chemical Biology

      Volume: 12 Pages: 2-2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Identification of Toyocamycin, an agent cytotoxic for multiple myeloma cells, as a potent inhibitor of ER stress-induced XBP1 mRNA splicing.2012
    • Author(s)
      Ri M, Tashiro E, Oikawa D, Shinjo S, Tokuda M, Yokouchi Y, Narita T, Masaki A, Ito A, Ding J, Kusumoto S, Ishida T, Komatsu H, Shiotsu Y, Ueda R, Iwawaki T, Imoto M, Iida S
    • Journal Title

      Blood Cancer J.

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Journal Article] A chemical genomic study identifyingdiversity in cell migration signaling in cancer cells.2012
    • Author(s)
      Magi S, Tashiro Eand Imoto M.
    • Journal Title

      Scientific Reports

      Volume: 2 Pages: 823-823

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Prevalence of Bordetella hinzii in mice in experimental facilities in Japan.2012
    • Author(s)
      Hayashimoto, N., Morita, H., Yasuda, M., Ishida, T., Kameda, S., Takakura, A., Itoh, T.
    • Journal Title

      Res.Vet.Sci.

      Volume: 93(2) Pages: 624-6

    • DOI

      10.1016/j.rvsc.2011.11.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] 2) Napyradiomycin A1, an inhibitor of mitochondrial complex I and II2012
    • Author(s)
      K. Yamamoto, E. Tashiro, K. Motohashi, H. Seto, and M. Imoto
    • Journal Title

      The Journal of Antibiotics

      Volume: 65 Pages: 211-214

    • DOI

      10.1038/ja.2011.138

    • NAID

      10030641374

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Journal Article] Inostamycin enhanced TRAIL-induced apoptosis through DR5 up-regulation on the cell surface2012
    • Author(s)
      Yamamoto K, Makino M, Watanapokasin R, Tashiro Eand Imoto M
    • Journal Title

      J. Antibiot.

      Volume: 65 Pages: 295-300

    • NAID

      10030797925

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Journal Article] Antitumor effects of novel highly hydrophilic and non-ATP-competitive MEK1/2 inhibitor, SMK-172012
    • Author(s)
      Kiga M, Tanzawa F, Iwasaki S, Inaba F, Fujiwara K, Iwadare H, Echigo T, Nakamura Y, Shibata T, Suzuki K, Yasumatsu, I Nakayama A, Sasazawa Y, Tashiro E, Imoto M , S. Kurakata S
    • Journal Title

      Anticancer Drugs

      Volume: 23 Pages: 119-130

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Journal Article] Comprehensive Predictions of Target Proteins Based on Protein-Chemical Interaction Using Virtual Screening and Experimental Verifications2012
    • Author(s)
      Kobayashi H, Harada, H, Nakamura M, Futamura Y, Ito A, Yoshida M, Iemura S, Shin-ya K, Doi T, Takahashi T, Natsume T, Imoto Mand Sakakibara Y
    • Journal Title

      BMC Chemical Biology

      Volume: 12 Pages: 2-2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Journal Article] Xanthohumol Impairs Autophagosome Maturation through Direct Inhibition of Valosin-Containing Protein2012
    • Author(s)
      Sasazawa Y, Kanagaki S, Tashiro E, Nogawa T, Muroi M, Kondoh Y, Osada H, Imoto M
    • Journal Title

      ACS Chemical Biology

      Volume: 7 Pages: 892-900

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Journal Article] Napyradiomycin A1, an inhibitor of mitochondrial complexes I and II2012
    • Author(s)
      Yamamoto K, Tashiro E, Motohashi K, Seto H and Imoto M
    • Journal Title

      J. Antibiot.

      Volume: 65 Pages: 211-214

    • NAID

      10030641374

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Journal Article] A chemical genomic study identifying diversity in cell migration sig2012
    • Author(s)
      Magi S, Tashiro E and Imoto M.
    • Journal Title

      Sci Rep

      Volume: 2 Pages: 823-823

    • DOI

      10.1038/srep00823

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140, KAKENHI-PROJECT-22651084, KAKENHI-PLANNED-23102006

  • [Journal Article] Identification of Toyocamycin, an agent cytotoxic for multiple myeloma cells2012
    • Author(s)
      Ri M, Tashiro E, Oikawa D, Shinjo S, Tokuda M, Yokouchi Y, Narita T, Masaki A, Ito A, Ding J, Kusumoto S, Ishida T, Komatsu H, Shiotsu Y, Ueda R, Iwawaki T, Imoto M, Iida S
    • Journal Title

      as a potent inhibitor of ER stress-induced XBP1 mRNA splicing. Blood Cancer J.e

      Volume: 79

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Target identification of bioactive compounds2012
    • Author(s)
      Tashiro Eand Imoto M
    • Journal Title

      Bioorg. & Med. Chem.

      Volume: 20 Pages: 1910-1921

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Journal Article] A New Convenient Cell-based Screening Method for Small Molecule Glycolytic Inhibitors2011
    • Author(s)
      Kitagawa M, Misawa M, Ogawa S, Tashiro E and Imoto M
    • Journal Title

      Biosci. Biotechnol. Biochem

      Volume: 75 Pages: 367-369

    • NAID

      10027898136

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Journal Article] A new, convenient cell-based screening method for small-molecule glycolytic inhibitors2011
    • Author(s)
      M.Kitagawa, M.Misawa, S.Ogawa, E.Tashiro, M.Imoto
    • Journal Title

      Biosci Biotechnol Biochem 75

      Pages: 367-369

    • NAID

      10027898136

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Journal Article] Mycotrienin II, a translation inhibitor that prevents ICAM-1 expression induced by pro-inflammatory cytokines2011
    • Author(s)
      Yamada Y, Tashiro ETaketani S, Imoto Mand Kataoka T
    • Journal Title

      J. Antibiot

      Volume: 64 Pages: 361-366

    • NAID

      10030638820

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Journal Article] Generation of "Unnatural Natural Product" library and identification of a small molecule inhibitor of XIAP2011
    • Author(s)
      Kawamura T, Matsubara K, Otaka H, Tashiro E, Shindo, K, Yanagita R. C., Irie K and Imoto M
    • Journal Title

      Bioorg. & Med. Chem.

      Volume: 19 Pages: 4377-4385

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Journal Article] Synthesis and anti-migrative evaluation of moverastin derivatives2011
    • Author(s)
      M.Sawada, S.Kubo, K.Matsumura, Y.Takemoto, H.Kobayashi, E.Tashiro, T.Kitahara, H.Watanabe, M.Imoto
    • Journal Title

      Bioorg Med Chem Lett 21

      Pages: 1385-1389

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Journal Article] Mycotrienin II, a translation inhibitor that prevents ICAM-1 expression induced by pro-inflammatory cytokines2011
    • Author(s)
      Yamada Y, Tashiro E, Taketani S, Imoto M and Kataoka T
    • Journal Title

      J. Antibiot.

      Volume: 64 Pages: 361-366

    • NAID

      10030638820

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Journal Article] Caffeine induces apoptosis by enhancement of autophagy via PI3K/Akt/mTOR/p70S6K inhibition.2011
    • Author(s)
      Saiki S, Sasazawa Y, Imamichi Y, Kawajiri S, Fujimaki T, Tanida I, Kobayashi H, Sato F, Kei-Ichi Ishikawa, Sato S, Imoto M, Hattori N.
    • Journal Title

      Autophagy

      Volume: 7 Pages: 176-187

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790853

  • [Journal Article] Oncological outcomes of the prostate cancer patients registered in 2004 : report from the Cancer Registration Committee of the JUA2011
    • Author(s)
      Fujimoto H, et al
    • Journal Title

      Int J Urol

      Volume: 18 Pages: 876-881

    • DOI

      10.1111/j.1442-2042.2011.02895.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] Mycotrienin II, a translation inhibitor that prevents ICAM-1 expression induced by pro-inflammatory cytokines2011
    • Author(s)
      Yamada Y, Tashiro ETaketani S, Imoto Mand Kataoka T
    • Journal Title

      J. Antibiot

      Volume: 64 Pages: 361-366

    • NAID

      10030638820

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Generation of "Unnatural Natural Product" library and identification of a small molecule inhibitor of XIAP2011
    • Author(s)
      T.Kawamura, K.Matsubara, H.Otaka, E.Tashiro, K.Shindo, R.C.Yanagita, K.Irie, M.Imoto
    • Journal Title

      Bioorg.& Med.Chem.

      Volume: 19 Pages: 4377-4385

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Synthesis and anti-migrative evaluation of moverastin derivatives2011
    • Author(s)
      Sawada M, Kubo, S Matsumura, K Takemoto Y, Kobayashi H, Tashiro E,Kitahara T, Watanabe H and Imoto M
    • Journal Title

      Bioorg.c & Med. Chem. Lett

      Volume: 21 Pages: 1385-1389

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Journal Article] Quinotrierixin inhibited ER stress-induced XBP1 mRNA splicing through inhibition of protein synthesis2011
    • Author(s)
      K.Yamamoto, E.Tashiro, M.Imoto
    • Journal Title

      Biosci Biotechnol Biochem 75

      Pages: 284-288

    • NAID

      10027897707

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Journal Article] Quinotrierixin Inhibits ER Stress-induced XBP1 mRNA Splicing through Inhibition of Protein Synthesis.2011
    • Author(s)
      K.Yamamoto, E.Tashiro, M.Imoto.
    • Journal Title

      Biosci.Biotechnol.Biochem.

      Volume: (In press 掲載決定)

    • NAID

      10027897707

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] A new, convenient cell-based screening method for small-molecule glycolytic inhibitors2011
    • Author(s)
      M.Kitagawa, M.Misawa, S.Ogawa, E.Tashiro, M.Imoto
    • Journal Title

      Biosci Biotechnol Biochem

      Volume: 75 Pages: 367-369

    • NAID

      10027898136

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Journal Article] Generation of "Unnatural Natural Product" library and identification of a small molecule inhibitor of XIAP2011
    • Author(s)
      Kawamura T, Matsubara K, Otaka H, Tashiro E, Shindo, K, Yanagita R. C., Irie K and Imoto M
    • Journal Title

      Bioorg. & Med. Chem

      Volume: 19 Pages: 4377-4385

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Journal Article] Involvement of 14-3-3 proteins in the second EGF-induced wave of Rac1 activation in the process of cell migration2011
    • Author(s)
      Kobayashi H, Ogura, Y, Sawada M, Nakayama T, Takano K, Minato Y, Takemoto Y, Tashiro E, Watanabe H & Imoto M
    • Journal Title

      J. Biol. Chem.

      Volume: 286 Pages: 39259-39268

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Journal Article] Caffeine induces apoptosis by enhancement of autophagy via PI3K/Akt/mTOR/p70S6K inhibition2011
    • Author(s)
      Saiki S, Sasazawa Y, Imamichi Y, Kawajiri S, Fujimaki T, Tanida I, Kobayashi H, Sato F, Kei-Ichi Ishikawa, Sato S, Imoto M, Hattori N
    • Journal Title

      Autophagy

      Volume: 7 Pages: 42-53

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Journal Article] A New Convenient Cell-based Screening Method for Small Molecule Glycolytic Inhibitors2011
    • Author(s)
      Kitagawa M, Misawa M, Ogawa S, Tashiro E and Imoto M
    • Journal Title

      Biosci. Biotechnol. Biochem.

      Volume: 75 Pages: 367-369

    • NAID

      10027898136

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Journal Article] Synthesis and anti-migrative evaluation of moverastin derivatives2011
    • Author(s)
      M.Sawada, S.Kubo, K.Matsumura, Y.Takemoto, H.Kobayashi, E.Tashiro, T.Kitahara, H.Watanabe, M.Imoto
    • Journal Title

      Bioorg.c & Med.l Chen.Lett.

      Volume: 21 Pages: 1385-1389

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Involvement of 14-3-3 proteins in the second EGF-induced wave of Rac1 activation in the process of cell migration2011
    • Author(s)
      H.Kobayashi, Y.Ogura, M.Sawada, R.Nakayama, K.Takano, Y.Minato, Y.Takemoto, E.Tashiro, H.Watanabe, M.Imoto
    • Journal Title

      J.Biol.Chem.

      Volume: 286 Pages: 39259-39268

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Caffeine induces apoptosis by enhancement of autophagy via PI3K/Akt/mTOR/p70S6K inhibition.2011
    • Author(s)
      Saiki S, Sasazawa Y, Imamichi Y, Kawajiri S, Fujimaki T, Tanida I, Kobayashi H, Sato F, Kei-Ichi Ishikawa, Sato S, Imoto M, Hattori N.
    • Journal Title

      Autophagy 7

      Pages: 176-87

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790853

  • [Journal Article] A New Convenient Cell-based Screening Method for Small Molecule Glycolytic Inhibitors.2011
    • Author(s)
      Kitagawa M, Misawa M, Ogawa S, Tashiro E and Imoto M
    • Journal Title

      Biosci. Biotechnol. Biochem

      Volume: 75 Pages: 367-369

    • NAID

      10027898136

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Synthesis and anti-migrative evaluation of moverastin derivatives.2011
    • Author(s)
      M.Sawada, S.Kubo, K.Matsumura, Y.Takemoto, H.Kobayashi, E.Tashiro, T.Kitahara, H.Watanabe, M.Imoto.
    • Journal Title

      Bioorganic & Medicinal Chemistry Letters

      Volume: (In press 掲載決定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Involvement of 14-3-3 proteins in the second EGF-induced wave of Rac1 activation in the process of cell migration2011
    • Author(s)
      H.Kobayashi, Y.Ogura, M.Sawada, R.Nakayama, K.Takano, Y.Minato, Y.Takemoto, E.Tashiro, H.Watanabe, M.Imoto
    • Journal Title

      J.Biol.Chem.

      Volume: 286 Pages: 39259-39268

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Journal Article] Caffeine induces apoptosis by enhancement of autophagy via PI3K/Akt/mTOR/p70S6K inhibition2011
    • Author(s)
      Saiki S, Sasazawa Y, Imamichi Y, Kawajiri S, Fujimaki T, Tanida I, Kobayashi H, Sato F, Kei-Ichi Ishikawa, Sato S, Imoto M, Hattori N
    • Journal Title

      Autophagy

      Volume: 7 Pages: 42-53

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Generation of "Unnatural Natural Product" library and identification of a small molecule inhibitor of XIAP2011
    • Author(s)
      T.Kawamura, K.Matsubara, H.Otaka, E.Tashiro, K.Shindo, R.C.Yanagita, K.Irie, M.Imoto
    • Journal Title

      Bioorg.& Med.Chem.

      Volume: 19 Pages: 4377-4386

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Journal Article] Involvement of 14-3-3 proteins in the second EGF-induced wave of Rac1 activation in the process of cell migration2011
    • Author(s)
      H.Kobayashi, Y.Ogura, M.Sawada, R.Nakayama, K.Takano, Y.Minato, Y.Takemoto, E.Tashiro, H.Watanabe, M.Imoto
    • Journal Title

      J.Biol.Chem.

      Volume: 286 Pages: 39259-39268

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Journal Article] Synthesis and anti-migrative evaluation of moverastin derivatives2011
    • Author(s)
      Sawada M, Kubo, S Matsumura, K Takemoto Y, Kobayashi H, Tashiro E, Kitahara T, Watanabe H and Imoto M
    • Journal Title

      Bioorg.c & Med. Chem. Lett.

      Volume: 21 Pages: 1385-1389

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Journal Article] Quinotrierixin Inhibits ER Stress-induced XBP1 mRNA Splicing through Inhibition of Protein Synthesis2011
    • Author(s)
      Yamamoto K, Tashiro E and Imoto M
    • Journal Title

      Biosci. Biotechnol. Biochem.

      Volume: 75 Pages: 284-288

    • NAID

      10027897707

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Journal Article] Generation of "Unnatural Natural Product" library and identification of a small molecule inhibitor of XIAP2011
    • Author(s)
      Kawamura T, Matsubara K, Otaka H, Tashiro E, Shindo, K, Yanagita R. C., Irie K and Imoto M
    • Journal Title

      Bioorg. & Med. Chem

      Volume: 19 Pages: 4377-4385

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Synthesis and anti-migrative evaluation of moverastin derivatives2011
    • Author(s)
      M.Sawada, S.Kubo, K.Matsumura, Y.Takemoto, H.Kobayashi, E.Tashiro, T.Kitahara, H.Watanabe, M.Imoto
    • Journal Title

      Bioorg Med Chem Lett

      Volume: 21 Pages: 1385-1389

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Journal Article] Synthesis and anti-migrative evaluation of moverastin derivatives2011
    • Author(s)
      M.Sawada, S.Kubo, K.Matsumura, Y.Takemoto, H.Kobayashi, E.Tashiro, T.Kitahara, H.Watanabe, M.Imoto
    • Journal Title

      Bioorg.c & Med.l Chem.Lett.

      Volume: 21 Pages: 1385-1389

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Journal Article] Involvement of 14-3-3 proteins in the second EGF-induced wave of Rac1 activation in the process of cell migration2011
    • Author(s)
      Kobayashi1 H, Ogura, Y, Sawada M, Nakayama T, Takano K, Minato Y, Takemoto Y, Tashiro E, Watanabe H & Imoto M.
    • Journal Title

      J. Biol. Chem

      Volume: 286 Pages: 39259-39268

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Synthesis and anti-migrative evaluation of moverastin derivatives.2011
    • Author(s)
      Sawada M, Kubo, S Matsumura, K Takemoto Y, Kobayashi H, Tashiro E, Kitahara T, Watanabe H and Imoto M
    • Journal Title

      Bioorg.c & Med. Chem. Lett

      Volume: 21 Pages: 1385-1389

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Quinotrierixin Inhibits ER Stress-induced XBP1 mRNA Splicing through Inhibition of Protein Synthesis2011
    • Author(s)
      Yamamoto K, Tashiro Eand Imoto M
    • Journal Title

      Biosci. Biotechnol. Biochem.

      Volume: 75 Pages: 284-288

    • NAID

      10027897707

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Quinotrierixin inhibited ER stress-induced XBP1 mRNA splicing through inhibition of protein synthesis2011
    • Author(s)
      K.Yamamoto, E.Tashiro, M.Imoto
    • Journal Title

      Biosci Biotechnol Biochem

      Volume: 75 Pages: 284-288

    • NAID

      10027897707

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Journal Article] Quinotrierixin Inhibits ER Stress-induced XBP1 mRNA Splicing through Inhibition of Protein Synthesis2011
    • Author(s)
      Yamamoto K, Tashiro Eand Imoto M
    • Journal Title

      Biosci. Biotechnol. Biochem.

      Volume: 75 Pages: 284-288

    • NAID

      10027897707

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Journal Article] Involvement of 14-3-3 proteins in the second epidermal growth factor-induced wave of Rac1 activation in the process of cell migration2011
    • Author(s)
      Hiroki Kobayashi, Yusuke Ogura, Masato Sawada, Ryoji Nakayama, Kei Takano, Yusuke Minato, Yasushi Takemoto, Etsu Tashiro, Hidenori Watanabe, Masaya Imoto
    • Journal Title

      J.Biol.Chem.

      Volume: 286 Pages: 39259-39268

    • DOI

      10.1074/jbc.m111.255489

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J03194, KAKENHI-ORGANIZER-23102001, KAKENHI-PLANNED-23102010

  • [Journal Article] Involvement of 14-3-3 proteins in the second EGF-induced wave of Rac1 activation in the process of cell migration2011
    • Author(s)
      Kobayashi1 H, Ogura, Y, Sawada M, Nakayama T, Takano K, Minato Y, Takemoto Y, Tashiro E, Watanabe H & Imoto M
    • Journal Title

      J. Biol. Chem

      Volume: 286 Pages: 39259-39268

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Journal Article] Caffeine induces apoptosis by enhancement of autophagy via PI3K/Akt/mTOR/p70S6K inhibition.2011
    • Author(s)
      S.Saiki, Y.Sasazawa, Y.Imamichi, S.Kawajiri, T.Fujimaki, I.Tanida, H.Kobayashi, F.Sato, S.Sato, K.Ishikawa, M.Imoto, N.Hattori
    • Journal Title

      Autophagy

      Volume: 7 Pages: 42-53

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Isolation and structure elucidation of a novel androgen antagonist, arabilin, produced by Streptomyces sp.MK756-CF12010
    • Author(s)
      T.Kawamura, T.Fujimaki, N.Hamanaka, K.Torii, H.Kobayashi, Y.Takahashi, M.Igarashi, N.Kinoshita, Y.Nishimura, E.Tashiro, M.Imoto
    • Journal Title

      J.Antibiot(Tokyo) 63

      Pages: 601-605

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Journal Article] Glyoxalase-I is a novel target against Bcr-Abl+leukemic cells acquiring stem-like characteristics in hypoxic environment2010
    • Author(s)
      Takeuchi M, Kimura S, Kuroda J, Ashihara E, KawataniM, Osada H, Umezawa K, Yasui E, Imoto M, Tsuruo T, Yokota A, Tanaka R, Nagao T, Nakahata N, Fujiyama Y Maekawa T
    • Journal Title

      Cell Death Diff.

      Volume: 17 Pages: 1211-1220

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Metabolomic identification of the target of the filopodia protrusion inhibitor glucopiericidin A2010
    • Author(s)
      Kitagawa M, Ikeda S, Tashiro E, Soga T, Imoto M.
    • Journal Title

      Chemistry and Biology

      Volume: 17 Pages: 989-998

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Journal Article] Glyoxalase-I is a novel target against Bcr-Abl^+leukemic cells acquiring stem-like characteristics in hypoxic environment.2010
    • Author(s)
      Takeuchi M, Kimura S, Kuroda J, Ashihara E, KawataniM, Osada H, Umezawa K, Yasui E, Imoto M, Tsuruo T, Yokota A, Tanaka R, Nagao T, Nakahata N, Fujiyama Y Maekawa T
    • Journal Title

      Cell Death Diff

      Volume: 17 Pages: 1211-1220

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Journal Article] Terpenoids produced by actinomycetes: isolation, structural elucidation and biosynthesis of new diterpenes, gifhornenolones A and B from Verrucosispora gifhornensis YM28-0882010
    • Author(s)
      M. Shirai. M. Okuda, K. Motohashi, M. Imoto, K. Furihata, Y. Matsuo, A. Katsuta, Y. Shizuri, H. Seto
    • Journal Title

      J. Antibiot

      Volume: 63 Pages: 245-250

    • NAID

      10030708411

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Journal Article] Metabolomic identification of the target of the filopodia protrusion inhibitor glucopiericidin A2010
    • Author(s)
      Kitagawa M, Ikeda S, Tashiro E, Soga T, Imoto M
    • Journal Title

      Chemistry and Biology

      Volume: 17 Pages: 989-998

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Total Synthesis of Incednam, the Aglycon of Incednine.2010
    • Author(s)
      T. Ohtani, S. Tsukamoto, H. Kanda, K. Misawa, Y. Urakawa, T. Fujimaki, M. Imoto,Y. Takahashi, D. Takahashi†, and K. Toshima
    • Journal Title

      Org. Lett.

      Volume: 12 Pages: 5068-5071

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Journal Article] Isolation and structure elucidation of a novel androgen antagonist, arabilin, produced by Streptomycessp. MK756-CF12010
    • Author(s)
      Kawamura T, Fujimaki T, Hamanaka N, Torii K, Kobayashi H, Takahashi Y, Igarashi M, Kinoshita N, Nishimura Y, Tashiro E, Imoto M
    • Journal Title

      J. Antibiot.

      Volume: 63 Pages: 601-605

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Journal Article] Mesenchyme cells can function to induce epithelial cell proliferation in starfish embryos.2010
    • Author(s)
      G.Hamanaka, M.Matsumoto, M.Imoto, H.Kaneko
    • Journal Title

      Developmental Dynamics 293

      Pages: 818-827

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310146

  • [Journal Article] Mesenchyme cells can function to induce epithelial cell proliferation in starfish embryos.2010
    • Author(s)
      G.Hamanaka, M.Matsumoto, M.Imoto, H.Kaneko
    • Journal Title

      Developmental Dynamics 293

      Pages: 818-827

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20015043

  • [Journal Article] Isolation and structure elucidation of a novel androgen antagonist, arabilin, produced by Streptomyces sp.MK756-CF12010
    • Author(s)
      T.Kawamura, T.Fujimaki, N.Hamanaka, K.Torii, H.Kobayashi, Y.Takahashi, M.Igarashi, N.Kinoshita, Y.Nishimura, E.Tashiro, M.Imoto
    • Journal Title

      J.Antibiot(Tokyo)

      Volume: 63 Pages: 601-605

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Journal Article] Terpenoids produced by actinomycetes: isolation, structural elucidation and biosynthesis of new diterpenes2010
    • Author(s)
      M. Shirai. M. Okuda, K. Motohashi, M. Imoto, K. Furihata, Y. Matsuo, A. Katsuta, Y. Shizuri, H. Seto
    • Journal Title

      gifhornenolones A and B from Verrucosispora gifhornensis YM28-088.J. Antibiot.

      Volume: 63 Pages: 245-250

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Distinct subcellular localization in the cytosol and apicoplast, unexpected dimerization and inhibition of Plasmodium falciparum glyoxalases2010
    • Author(s)
      M. Urscher, JM. Przyborski, M. Imotoand M. Deponte.
    • Journal Title

      Mol Microbiol.

      Volume: 76 Pages: 92-103

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Mesenchyme cells can function to induce epithelial cell proliferation in starfish embryos.2010
    • Author(s)
      G. Hamanaka, M. Matsumoto, M. Imoto, H. Kaneko
    • Journal Title

      Develomental Dynamics 293

      Pages: 818-827

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310146

  • [Journal Article] Glyoxalase-I is a novel target against Bcr-Abl^+ leukemic cells acquiring stem-like characteristics in hypoxic environment.2010
    • Author(s)
      M.Takeuchi, S.Kimura, J.Kuroda, E.Ashihara, M.Kawatani, H.Osada, K.Umezawa, E.Yasui, M.Imoto, T.Tsuruo, A.Yokota, R.Tanaka, R.Nagao, T.Nakahata, Y.Fujiyama, T.Maekawa
    • Journal Title

      Cell Death Diff. (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310146

  • [Journal Article] Total Synthesis of Incednam, the Aglycon of Incednine2010
    • Author(s)
      T. Ohtani, S. Tsukamoto, H. Kanda, K. Misawa, Y. Urakawa, T. Fujimaki, M. Imoto,Y. Takahashi, D. Takahashi†, and K. Toshima
    • Journal Title

      Org. Lett

      Volume: 12 Pages: 5068-5071

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Mesenchyme cells can function to induce epithelial cell proliferation in starfish embryos2010
    • Author(s)
      G. Hamanaka, M. Matsumoto, M. Imotoand H. Kaneko:
    • Journal Title

      Develomental Dynamics

      Volume: 293 Pages: 818-827

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Metabolomic identification of the target of the filopodia protrusion inhibitor glucopiericidin A2010
    • Author(s)
      M.Kitagawa, S.Ikeda, E.Tashiro, T.Soga, M.Imoto
    • Journal Title

      Chemistry and Biology

      Volume: 17 Pages: 989-998

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Journal Article] Mesenchyme cells can function to induce epithelial cell proliferation in starfish embryos.2010
    • Author(s)
      G. Hamanaka, M. Matsumoto, M. Imotoand H. Kaneko
    • Journal Title

      Develomental Dynamics

      Volume: 293 Pages: 818-827

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Journal Article] Isolation and structure elucidation of a novel androgen antagonist2010
    • Author(s)
      Kawamura T, Fujimaki T, Hamanaka N, Torii K, Kobayashi H, Takahashi Y, Igarashi M, Kinoshita N, Nishimura Y, Tashiro E, Imoto M
    • Journal Title

      arabilin, produced by Streptomycessp. MK756-CF1. J. Antibiot.

      Volume: 63 Pages: 601-605

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Journal Article] Metabolomic identification of the target of the filopodia protrusion inhibitor glucopiericidin A2010
    • Author(s)
      M.Kitagawa, S.Ikeda, E.Tashiro, T.Soga, M.Imoto
    • Journal Title

      Chemistry and Biology 17

      Pages: 989-998

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Journal Article] Distinct subcellular localization in the cytosol and apicoplast, unexpected dimerization and inhibition of Plasmodium falciparum glyoxalases2010
    • Author(s)
      M. Urscher, JM. Przyborski, M. Imotoand M. Deponte
    • Journal Title

      Mol Microbiol.

      Volume: 76 Pages: 92-103

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Journal Article] Oligomycin induced the proteasomal degradation of cyclin D1 protein2009
    • Author(s)
      M.Kanai, S.Iba, R.Okada, E.Tashiro, M.Imoto
    • Journal Title

      J.Antibiot 62

      Pages: 425-429

    • NAID

      10030635974

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310146

  • [Journal Article] V-ATPase inhibitors overcome Bcl-xL-mediated chemoresistance throughrestoration of a caspase-independent apoptotic pathway2009
    • Author(s)
      Sasazawa Y, Futamura Y, Tashiro E, Imoto M.
    • Journal Title

      Cancer Sci 100

      Pages: 1460-1467

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17012025

  • [Journal Article] V-ATPase inhibitors overcome Bcl-xL-mediated chemoresistance through restoration of a caspase-independent apoptotic pathway.2009
    • Author(s)
      Y. Sasazawa, Y. Futamura, E. Tashiro, M. Imoto
    • Journal Title

      Cancer Science 100

      Pages: 1460-1467

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310146

  • [Journal Article] Transcriptional regulation of human fibroblast growth factor receptor 1 by E2F-1.2009
    • Author(s)
      M. Kanai, E. Tashiro, H. Maruki, Y. Minato, M. Imoto
    • Journal Title

      Gene 438

      Pages: 49-53

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310146

  • [Journal Article] Oligomycin induced the proteasomal degradation of cyclin D12009
    • Author(s)
      M.Kanai, S.Iba, R.Okada, E.Tashiro, M.Imoto
    • Journal Title

      J.Antibiot(Tokyo) 62

      Pages: 425-429

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Journal Article] Transcriptional regulation of human fibroblast growth factor receptor 1 by E2F-1.2009
    • Author(s)
      M.Kanai, E.Tashiro, H.Maruki, Y.Minato, M.Imoto
    • Journal Title

      Gene 438

      Pages: 49-56

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Journal Article] 微生物生理活性物質のケミカルバイオロジー2009
    • Author(s)
      田代悦, 井本正哉
    • Journal Title

      化学と生物 47

      Pages: 193-201

    • NAID

      10026435019

    • Data Source
      KAKENHI-PROJECT-20611016

  • [Journal Article] Transcriptional regulation of human fibroblast growth factor receptor 1 by E2F-12009
    • Author(s)
      M.Kanai, E.Tashiro, H.Maruki, Y.Minato, M.Imoto
    • Journal Title

      Gene 438

      Pages: 49-56

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Journal Article] V-ATPase inhibitors overcome Bcl-xL-mediated chemoresistance through restoration of a caspase-independent apoptotic pathway2009
    • Author(s)
      Sasazawa Y, Futamura Y, Tashiro E, Imoto M.
    • Journal Title

      Cancer Science 100

      Pages: 1460-1467

    • Data Source
      KAKENHI-PROJECT-17012025

  • [Journal Article] Oligomycin induced the proteasomal degradation of cyclin D1 protein.2009
    • Author(s)
      M. Kanai, S. Iba, R. Okada, E. Tashiro, M. Imoto
    • Journal Title

      J. Antibiot 62

      Pages: 425-429

    • NAID

      10030635974

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310146

  • [Journal Article] Sakakibara. Integrating statistical predictions and experimental verifications for enhancing protein-chemical interaction predictions in virtual screening.2009
    • Author(s)
      N. Nagamine, T. Shirakawa, Y. Minato, K. Torii, H. Kobayashi, M. Imoto, Y. Sakakibara
    • Journal Title

      PLos Comput Biol e1000397

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310146

  • [Journal Article] Oligomycin induced the proteasomal degradation of cyclin D12009
    • Author(s)
      M.Kanai, S.Iba, R.Okada, E.Tashiro, M.Imoto
    • Journal Title

      J.Antibot(Tokyo) 62

      Pages: 425-429

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Journal Article] V-ATPase Inhibitors Overcome Bcl-xL-mediated Chemoresistance through Restoration of a Caspase-independent Apoptotic Pathway2009
    • Author(s)
      Y.Sasazawa, Y.Futamura, E.Tashiro, M.Imoto
    • Journal Title

      Cancr Science 100

      Pages: 1460-1467

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Journal Article] V-ATPase Inhibitors Overcome Bcl-xL-mediated Chemoresistance through Restoration of a Caspase-independent Apoptotic Pathway2009
    • Author(s)
      Y.Sasazawa, Y.Futamura, E.Tashiro, M.Imoto
    • Journal Title

      Cancer Science 100

      Pages: 1460-1467

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Journal Article] Oligomycin induced the proteasomal degradation of cyclin D1 oprotein2009
    • Author(s)
      M.Kanai, S.Iba, R.Okada, E.Tashiro, M.Imoto
    • Journal Title

      J.Antibiot 62

      Pages: 425-429

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20015043

  • [Journal Article] Transcriptional regulation of human fibroblast growth factor receptorl by E2F-1.2009
    • Author(s)
      Kanai, M. Tashiro, E. Maruki, H. Minato, Y. Imoto, M.
    • Journal Title

      Gene (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17012025

  • [Journal Article] V-ATPase inhibitors overcome Bcl-xL-mediated chemoresistance through restoration of a caspase-independent apoptotic pathway.2009
    • Author(s)
      Sasazawa, Y. Futamura, Y. Tashiro, E. Imoto. M.
    • Journal Title

      Cancer science (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17012025

  • [Journal Article] SAR study of a Novel Triene-ansamycin Group Compound, Quinotrierixin, and Related Compounds, as Inhibitors of ER Stress-induced XBP1 Activation. I.Taxonomy, Fermentation, Isolation, and Biological activities and SAR study2008
    • Author(s)
      T.Kawamura, E.Tashiro, K.Yamamoto, K Shindo, M.Imoto
    • Journal Title

      J.Antibiot(Tokyo) 61

      Pages: 303-311

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Journal Article] Identification and characterization of mouse type II platelet-derived growth factor receptor a transcript.2008
    • Author(s)
      Y. Minato, et. al. and M. Imoto
    • Journal Title

      Biosci.Biotechnol.Biochem., 72

      Pages: 759-766

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310146

  • [Journal Article] The identification of an osteoclastogenesis inhibitor through the inhibition of glyoxalase I2008
    • Author(s)
      M. Kawatani, H. Okumura, K Honda, N. Kanoh, M. Muroi, N. Dohmae, M. Takami, M. Kitagawa, Y. Futamura, M. Imoto, H. Osada
    • Journal Title

      Proc. Natl. Acad. Sci. USA 105

      Pages: 11691-11696

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310146

  • [Journal Article] Discovery of Incednine as a Potent Modulator of the Anti-apoptotic Function of Bel-xL from Microbial Origin2008
    • Author(s)
      Y. Futamura, R. Sawa, Y. Umezawa, M. Igarashi, H. Nakamura, K. Hasegawa, M. Yamasaki, E. Tashiro, Y. Takahashi, Y. Akamatsu, M. Imoto
    • Journal Title

      J. Am. Chem. Soc. 130

      Pages: 1822-1823

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310146

  • [Journal Article] Discovery of Incednine as a Potent Modulator of the Anti-apoptotic Function of Bcl-xL from Microbial Origin2008
    • Author(s)
      Y.Futamura, R.Sawa, Y.Umezawa, M.Igarashi, H.Nakamura, K.Hasegawa, M.Yamasaki, E.Tashiro, Y.Takahashi, Y.Akamatsu, M.Imoto
    • Journal Title

      The Journal of American Chemical Society 130

      Pages: 1822-1823

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Journal Article] Identification and characterization of mouse type II platelet-derived growth factor receptor a transcript.2008
    • Author(s)
      Y. Minato, Y. Nihei, Y. Kodama, E. Tashiro, M. Kanai, M. Imoto
    • Journal Title

      Biosci. Biotechnol. Biochem. 72

      Pages: 759-766

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310146

  • [Journal Article] Discovery of Incednine as a Potent Modulator of the Anti-apoptotic Function of Bc1-xL from Microbial Origin2008
    • Author(s)
      Y. Futamura, R. Sawa, Y. Umezawa, M. Igarashi, H. Nakamura, K. Hasegawa, M. Yamasaki, E. Tashiro, Y. Takahashi, Y. Akamatsu, and M. Imoto
    • Journal Title

      J. Am. Chem. Soc 130

      Pages: 1822-1823

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20015043

  • [Journal Article] Discovery of Incednine as a Potent Modulator of the Anti-apoptotic Function of Bcl-xL from Microbial Origin.2008
    • Author(s)
      Y. Futamura, R. Sawa, Y. Umezawa, M. Igarashi, H. Nakamura, K. Hasegawa, M. Yamasaki, E. Tashiro, Y. Takahashi, Y. Akamatsu, M. Imoto
    • Journal Title

      J. Am. Chem. Soc. 130

      Pages: 1822-1823

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310146

  • [Journal Article] The identification of an osteoclastogenesis inhibitor through the inhibit ion of glyoxalase I2008
    • Author(s)
      M. Kawatani, H. Okumura, K Honda, N. Kanoh, M. Muroi, N. Dohmae, M. Takami, M. Kitagawa, Y. Futamura, M. Imoto, and H. Osada
    • Journal Title

      Proc. Natl. Acad. Sci. USA 105

      Pages: 11691-11696

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20015043

  • [Journal Article] Identification and characterization of mouse type II platelet-derived growth factor receptor a transcript2008
    • Author(s)
      Y. Minato, Y. Nihei, Y. Kodama, E. Tashiro, M. Kanai and M. Imoto
    • Journal Title

      Biosci. Biotechnol. Biochem 72

      Pages: 759-766

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20015043

  • [Journal Article] SAR Study of a Novel Triene-ansamycin Group Compound, Quinotrierixin, and Related Compounds, as Inhibitors of ER Stress-induced XBP1 Activation. II. Structure Elucidation.2008
    • Author(s)
      T. Kawamura, E. Tashiro, K. Shindo, M. Imoto
    • Journal Title

      J. Antibiot 61

      Pages: 312-317

    • NAID

      10021927823

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310146

  • [Journal Article] Identification and characterization of mouse type II platelet-derived growth factor receptor a transcript2008
    • Author(s)
      Y.Minato, Y.Nihei, Y.Kodama, E.Tashiro, M.Kanai, M.Imoto
    • Journal Title

      Biosci.Biotechnol.Biochem. 72

      Pages: 759-766

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Journal Article] Discovery of Incednine as a Potent Modulator of the Anti-apoptotic Function of Bcl-xL from Microbial Origin.2008
    • Author(s)
      Futamura, Y. Sawa, R. Umezawa, Y. Igarashi, M. Nakamura, H. Hasegawa, K. Yamasaki, M. Tashiro, E. Takahashi, Y. Akamatsu, Y.and Imoto, M.
    • Journal Title

      J. Am. Chem. Soc. (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17012025

  • [Journal Article] Discovery of Incednine as a Potent Modulator of the Anti-apoptotic Function of Bcl-xL from Microbial Origin.2008
    • Author(s)
      Y. Futamura, et. al., and M. Imoto
    • Journal Title

      J.Am.Chem.Soc 130

      Pages: 1822-1823

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310146

  • [Journal Article] Identification and characterization of mouse type II platelet-derived growth factor receptor α transcript.2008
    • Author(s)
      Y. Minato, Y. Nihei, Y. Kodama, E. Tashiro, M. Kanai, M. Imoto
    • Journal Title

      Biosci. Biotechnol. Biochem. 72

      Pages: 759-766

    • NAID

      10027525635

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310146

  • [Journal Article] SAR Study of a Novel Triene-ansamycin Group Compound, Quinotrierixin, and Related Compounds, as Inhibitors of ER Stress-induced XBP1 Activation. I. Taxonomy, Fermentation, Isolation, Biological Activities and SAR Study.2008
    • Author(s)
      T. Kawamura, E. Tashiro, K. Yamamoto, K. Shindo, M. Imoto
    • Journal Title

      J. Antibiot 61

      Pages: 303-311

    • NAID

      10021927806

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310146

  • [Journal Article] The identification of an osteoclastogenesis inhibitor through the inhibition of glyoxalase2008
    • Author(s)
      M. Kawatani, H. Okumura, K Honda, N. Kanoh, M. Muroi, N. Dohmae, M. Takami, M. Kitagawa, Y. Futamura, M. Imoto, H. Osada
    • Journal Title

      I. Proc. Natl. Acad. Sci. U S A 105

      Pages: 11691-11696

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310146

  • [Journal Article] SAR study of a Novel Triene-ansamycin Group Compound, Quinotrierixin, and Related Compounds, as Inhibitors of ER Stress-induced XBP1 Activation. II.Structure Elucidation2008
    • Author(s)
      T.Kawamura, E.Tashiro, K.Shindo, M.Imoto
    • Journal Title

      J.Antibiot(Tokyo) 61

      Pages: 312-317

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20611016

  • [Journal Article] Synthesis and antitumor activity of combretastatin D-4.2008
    • Author(s)
      K. Uno, T. Tanabe, T. Ogamino, R. Okada, M. Imoto, S. Nishiyama
    • Journal Title

      Heterocycles 75

      Pages: 291-296

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310146

  • [Journal Article] The identification of anosteoclastogenesis inhibitor through the inhibition of glyoxalase I.2008
    • Author(s)
      Kawatani M, Okumura H, Honda K, Kanoh N, Muroi M, Dohmae N, Takami M, Kitagawa M, Futamura Y, Imoto M, Osada H.
    • Journal Title

      Proc Natl Acad Sci, USA 105

      Pages: 11691-11696

    • Data Source
      KAKENHI-PROJECT-17012025

  • [Journal Article] Promotion of glioma cell survival by acyl-CoA synthetase 5 under extracellular acidosis conditions.2008
    • Author(s)
      Mashima, T. Sato, S. Sugimoto, Y. Tsuruo, T. Seimiya, H.
    • Journal Title

      Oncogene 28

      Pages: 9-19

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17012025

  • [Journal Article] Functions of cyclin D1 as an oncogene and regulation of cyclin D1 expression.2007
    • Author(s)
      E. Tashiro, A. Tsuchiya, M. Imoto
    • Journal Title

      Cancer Science 98

      Pages: 629-635

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310146

  • [Journal Article] Functions of cyclin D1 as an oncogene and regulation of cyclin D1 expression2007
    • Author(s)
      Tashiro, E., Tsuchiya, A., Imoto M.
    • Journal Title

      Cancer Science (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16300095

  • [Journal Article] Involvement of PP2A nuclear accumulation and subsequent inactivation of AP-1 in leptomycin B-inhibited cyclin D1 expression2007
    • Author(s)
      Tsuchiya, A., Tashiro, E., Yoshida, M., Imoto, M.
    • Journal Title

      Oncogene 26

      Pages: 1522-1532

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16300095

  • [Journal Article] Involvement of PP2A nuclear accumulation and subsequent inactivation of AP-1 in leptomycin B-inhibited cyclin D1 expression.2007
    • Author(s)
      Tsuchiya, A. Tashiro, E. Yoshida, M. and Imoto, M.
    • Journal Title

      Oncogene 26

      Pages: 1522-1532

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17012025

  • [Journal Article] Functions of cyclin D1 as an oncogene and regulation of cyclin D1 expression2007
    • Author(s)
      Tashiro, E., Tsuchiya, A., Imoto M.
    • Journal Title

      Cancer Science, (in press)

    • Data Source
      KAKENHI-PROJECT-16300095

  • [Journal Article] Transcriptional regulation of a new variant of human platelet-derived growth factor receptor a transcript by E2F-1.2007
    • Author(s)
      Y. Minato, E. Tashiro, M. Kanai, Y. Nihei, Y. Kodama, M. Imoto
    • Journal Title

      Gene 403

      Pages: 89-97

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310146

  • [Journal Article] Involvement of PP2A nuclear accumulation and subsequent inactivation of AP-1 in leptomycin B-inhibited cyclin D1 expression.2007
    • Author(s)
      Tsuchiya, A., Tashiro, E., Yoshida, M., Imoto, M.
    • Journal Title

      Oncogene. 26

      Pages: 1522-1532

    • Data Source
      KAKENHI-PROJECT-17012025

  • [Journal Article] Common Peak Approach Using Mass Spectrometry Data Sets for Predicting the Effects of Anticancer Drugs on Breast Cancer.2007
    • Author(s)
      Ushijima, M. Miyata, S. Eguchi, S. Kawakita, M. Yoshimoto, M. Iwase, T. Akiyama, F. Sakamoto, G. Nagasaki, K. Miki, Y. Noda, T. Hoshikawa, Y and Matsuura. M.
    • Journal Title

      Cancer Informatics. 3

      Pages: 285-293

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17012025

  • [Journal Article] Trierixin,a Novel Inhibitor of ER stress-induced XBP1 Activation from Streptomyces sp.I.Taxonomy,Fermentation,Isolation,and Biological activides.2007
    • Author(s)
      E. Tashiro, et. al. and M. Imoto:
    • Journal Title

      J.Antiobiot 60

      Pages: 547-553

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310146

  • [Journal Article] Common peak approach by semi-supervised learning using mass spectrometry datasets for predicting effects on anticancer drugs on breast cancer2007
    • Author(s)
      Ushijima M, Miyata S, Eguchi S, Kawakita M, Yoshimoto M, Iwase T, Akiyama F, Sakamoto G, Nagasaki K, Miki Y, Noda T, Hoshikawa Y, Matsuura M.
    • Journal Title

      Cancer Informatics 3

      Pages: 285-93

    • Data Source
      KAKENHI-PROJECT-17012025

  • [Journal Article] Trierixin, a Novel Inhibitor of ER Stress-induced XBP1 Activation from Streptomyces sp. II. Structure Elucidation2007
    • Author(s)
      Y. Futamura, E. Tashiro, N. Hironiwa, J. Kohno, M. Nishio, K. Shindo, M. Imoto
    • Journal Title

      J. Antiobiot 60

      Pages: 582-585

    • NAID

      10019831014

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310146

  • [Journal Article] Trierixin, a Novel Inhibitor of ER stress-induced XBP1 Activation from Streptomyces sp. I. Taxonomy, Fermentation, Isolation, and Biological activities.2007
    • Author(s)
      E. Tashiro, N. Hironiwa, M. Kitagawa, Y. Futamura, M. Imoto
    • Journal Title

      J. Antiobiot 60

      Pages: 547-553

    • NAID

      10019830891

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310146

  • [Journal Article] Involvement of PP2A nuclear accumulation and subsequent inactivation of AP-1 in leptomycin B-inhibited cyclin D1 expression.2007
    • Author(s)
      A. Tsuchiya, E. Tashiro, M. Yoshida, M. Imoto
    • Journal Title

      Oncogene 26

      Pages: 1522-1532

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310146

  • [Journal Article] Design, synthesis, and evaluation of cyclic amide/imide-bearing hydroxamic acid derivatives as class-selective histone deacetylase(HDAC)inhibitors.2006
    • Author(s)
      Shinji, C., Maeda, S., Imai, K., Yoshida, M., Hashimoto, Y., Miyachi, H.
    • Journal Title

      Bioorg Med Chem. 14

      Pages: 7625-7651

    • Data Source
      KAKENHI-PROJECT-17012025

  • [Journal Article] Antitumor effect of kigamicin D on mouse tumor models.2006
    • Author(s)
      Masuda, T., Ohba, S., Kawada, M., Osono, M., Ikeda, D., Esumi, H., Kunimoto, S.
    • Journal Title

      J Antibiot 59

      Pages: 209-214

    • NAID

      10017477695

    • Data Source
      KAKENHI-PROJECT-17012025

  • [Journal Article] Modification of pyrimidine derivatives from antiviral agents to antitumor agents.2006
    • Author(s)
      Kimura, H., Katoh, T., Kajimoto, T., Node, M., Hisaki, M., Sugimoto, Y., Majima, T., Uehara, Y., Yamori, T.
    • Journal Title

      Anticancer Res. 26

      Pages: 91-97

    • Data Source
      KAKENHI-PROJECT-17012025

  • [Journal Article] Suppression of multidrug resistance by migrastatin.2006
    • Author(s)
      Takemoto, Y., Tashiro, E., Imoto, M.
    • Journal Title

      J. Antibiot. 59

      Pages: 435-438

    • NAID

      10017649544

    • Data Source
      KAKENHI-PROJECT-17012025

  • [Journal Article] Chemistry and Biology of Moverastins, inhibitors of cancer cell migration, produced by Aspergillus2005
    • Author(s)
      Y.Takemoto, H.Watanabe, K.Uchida, K.Matsumura, K.Nakae, E.Tashiro, K.Shindo, T.Kitahara, M.Imoto
    • Journal Title

      Chemistry ＆ Biology 12・12

      Pages: 1337-1347

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16300095

  • [Journal Article] GSK-3 directly phosphorylates and activates MARK2/PAR-12005
    • Author(s)
      S.Kosuga, E.Tashiro, T.Kajioka, M.Ueki, Y.Shimizu, M.Imoto
    • Journal Title

      Journal of Biological Chemistry 280・52

      Pages: 42715-42722

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16300095

  • [Journal Article] Synthesis of the naphthalene-derived inhibitors against Cdc25A dual-specificity protein phosphatase and their biological activity2005
    • Author(s)
      A.Shinbashi, A.Tsuchiya, M.Imoto, S.Nishiyama
    • Journal Title

      Bioorganic & Medicinal Chemistry Letters 15

      Pages: 61-65

    • Data Source
      KAKENHI-PROJECT-15650054

  • [Journal Article] Chemistry and Biology of Moverastins, inhibitors of cancer cell migration, produced by Aspergillus2005
    • Author(s)
      Y.Takemoto, H.Watanabe, K.Uchida, K.Matsumura, K.Nakae, E.Tashiro, K.Shindo, T.Kitahara, M.Imoto
    • Journal Title

      Chemistry ＆ Biology 12(12)

      Pages: 1337-1347

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16300095

  • [Journal Article] Synthesis of the naphthalene-derived inhibitors against Cdc25A dual-specificity protein phosphatase and their biological activity2005
    • Author(s)
      A.Shinbashi, A.Tsuchiya, M.Imoto, S.Nishiyama
    • Journal Title

      Bioorganic & Medicinal Chemistry Letters 15

      Pages: 61-65

    • Data Source
      KAKENHI-PROJECT-12217133

  • [Journal Article] Synthesis of the naphthalene-derived inhibitors against Cdc25A dual-specificity protein phosphatase and their biological activity2005
    • Author(s)
      A.Shinbashi, A.Tsuchiya, M.Imoto, S.Nishiyama
    • Journal Title

      Bioorganic ＆ Medicinal Chemistry Letters 15

      Pages: 61-65

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16300095

  • [Journal Article] Synthesis of the naphthalene-derived inhibitors against Cdc25A dual-specificity protein phosphatase and their biological activity2005
    • Author(s)
      A.Shinbashi, A.Tsuchiya, M.Imoto, S.Nishiyama
    • Journal Title

      Bioorganic & Medicinal Chemistry Letters 15

      Pages: 61-65

    • Data Source
      KAKENHI-PROJECT-16300095

  • [Journal Article] Synthesis of the naphthalene-derived inhibitors against Cdc25A dual-specificity protein phosphatase and their biological activity2005
    • Author(s)
      A.Shinbashi, A.Tsuchiya, N.Imoto, S.Nishiyama
    • Journal Title

      Bioorganic ＆ Medicinal Chemistry Letters 15

      Pages: 61-65

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16300095

  • [Journal Article] Design and synthesis of phthalimide-type histone deacetylase2005
    • Author(s)
      Shinji, C., Nakamura, T., Maeda, S., Yoshida, M., Hashimoto, Y., Miyachi, H
    • Journal Title

      Bioorg.Med.Chem.Lett. 15(20)

      Pages: 4427-4431

    • Data Source
      KAKENHI-PROJECT-17012025

  • [Journal Article] GSK-3 directly phosphorylates and activates MAR K2/PAR-12005
    • Author(s)
      S.Kosuga, E.Tashiro, T.Kajioka, M.Ueki, Y.Shimizu, M.Imoto
    • Journal Title

      Journal of Biological Chemistry 280(52)

      Pages: 42715-42722

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16300095

  • [Journal Article] Chemistry and Biology of Moverastins, inhibitors of cancer cell migration, produced by Aspergillus2005
    • Author(s)
      Takemoto Y, Watanabe H, Uchida K, Matsumura K, Nakae K, Tashiro E, Shindo K, Kitahara T, Imoto M.
    • Journal Title

      Chem.Biol. 12(12)

      Pages: 1337-1347

    • Data Source
      KAKENHI-PROJECT-17012025

  • [Journal Article] Chemistry and Biology of Moverastins, inhibitors of cancer cell migration, produced by Aspergillus2005
    • Author(s)
      Y.Takemoto, H.Watanabe, K.Uchida, K.Matsumura, K.Nakae, E.Tashiro, K.Shindo, T.Kitahara, M.Imoto
    • Journal Title

      Chemistry & Biology 12・12

      Pages: 1337-1347

    • Data Source
      KAKENHI-PROJECT-16300095

  • [Journal Article] The synthesis amd Biological activity of pyranonaphthoquione derivative from Streptomyces sp.And their related substances2004
    • Author(s)
      A.Shinbashi, A.Tsuchiya, M.Imoto, S.Nishiyama
    • Journal Title

      Bull.Chem.Soc.Japan 77

      Pages: 1925-1930

    • Data Source
      KAKENHI-PROJECT-12217133

  • [Journal Article] The synthesis and Biological activity of pyranonaphthoquione derivatives from Streptomyces sp. and their related substances2004
    • Author(s)
      A.Shinbashi, A.Tsuchiya, M.Imoto, S.Nishiyama
    • Journal Title

      Bull. Chem. Soc. Japan 77

      Pages: 1925-1930

    • NAID

      10013737952

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16300095

  • [Journal Article] The synthesis amd Biological activity of pyranonaphthoquione derivatives from Streptomyces sp.And their related substances.2004
    • Author(s)
      A.Shinbashi, A.Tsuchiya, M.Imoto, S.Nishiyama
    • Journal Title

      Bull.Chem.Soc.Japan 77

      Pages: 1925-1930

    • Data Source
      KAKENHI-PROJECT-15650054

  • [Journal Article] The synthesis and Biological activity of pyranonaphthoquione derivatives from Streptomyces sp. and their related substances2004
    • Author(s)
      A.Shinbashi, A.Tsuchiya, M.Imoto, S.Nishiyama
    • Journal Title

      Bull.Chem.Soc.Japan 77

      Pages: 1925-1930

    • NAID

      10013737952

    • Data Source
      KAKENHI-PROJECT-16300095

  • [Journal Article] Glyoxalase-I is a novel target against Bcr-Abl^+ leukemic cells acquiring stem-like characteristics in hypoxic environment.
    • Author(s)
      M.Takeuchi, S.Kimura, J.Kuroda, E.Ashihara, M.Kawatani, H.Osada, K.Umezawa, E.Yasui, M.Imoto, T.Tsuruo, A.Yokota, R.Tanaka, R.Nagao, T.Nakahata, Y. Fujiyama, T.Maekawa
    • Journal Title

      Cell Death Diff. (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20015043

  • [Journal Article] Glyoxalase-I is a novel target against Bcr-Abl+ leukemic cells acquiring stem-like characteristics in hypoxic environment.
    • Author(s)
      M. Takeuchi, S. Kimura, J. Kuroda, E. Ashihara, M. Kawatani, H. Osada, K. Umezawa, E. Yasui, M. Imoto, T. Tsuruo, A. Yokota, R. Tanaka, R. Nagao, T. Nakahata, Y. Fujiyama, T. Maekawa
    • Journal Title

      Cell Death Diff. (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19310146

  • [Journal Article] Novel derivatives of aclacinomycin A block cancer cell migration through inhibition of farnesyl transferase.
    • Author(s)
      Magi S, Shitara T, Takemoto Y, Sawada M, Kitagawa M, Tashiro E. Takahashi Y, Imoto M
    • Journal Title

      J. Antibiot

      Volume: (in press)

    • NAID

      10031163117

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Journal Article] Novel derivatives of aclacinomycin A block cancer cell migration through inhibition of farnesyl transferase
    • Author(s)
      Magi S, Shitara T, Takemoto Y, Sawada M, Kitagawa M, Tashiro E. Takahashi Y, Imoto M
    • Journal Title

      J. Antibiot

    • NAID

      10031163117

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Patent] 化合物又はその塩、及びパーキンソン病治療薬又は予防薬2017
    • Inventor(s)
      井本正哉、斉木臣二、他
    • Industrial Property Rights Holder
      井本正哉、斉木臣二、他
    • Industrial Property Rights Type
      特許
    • Filing Date
      2017
    • Acquisition Date
      2017
    • Overseas
    • Data Source
      KAKENHI-PLANNED-25111007

  • [Presentation] がん幹細胞を標的とした抗がん剤シーズ探索系の構築2021
    • Author(s)
      池田拓慧, 川見美里, 井本正哉, 掛谷秀昭
    • Organizer
      日本薬学会第141年会
    • Data Source
      KAKENHI-PLANNED-17H06401

  • [Presentation] 5-Aminolevulinic acid overcomes hypoxia-induced resistance to radiation therapy thorough increase of mitochondrial reactive oxygen species in prostate cancer2020
    • Author(s)
      Owari T, Kishi S, Mori S, Miyake M, Nakai Y, Tanaka N, Fujimoto K, Kuniyasu H
    • Organizer
      79th Annual Meeting of Japanese Association for Cancer, Hiroshima, 2020.10.1-3
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] Formycin Aによる去勢抵抗性前立腺がん細胞選択的細胞死誘導2020
    • Author(s)
      武井 智暉, 濱村 祐輝, 本郷 周, 小坂 威雄, 大家 基嗣, 井本 正哉
    • Organizer
      日本がん分子標的治療学会
    • Data Source
      KAKENHI-PROJECT-18H02099

  • [Presentation] Rodent specific 4.5SH RNA is essential for the early development in mouse2020
    • Author(s)
      Ikuko Yamamoto, Michiko Sugimoto, Kimi Araki, Yu Suzuki, Takehiko Kobayashi, Shinichi Nakagawa
    • Organizer
      25th Annual Meeting of the RNA Society
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] Impact of fatty acid synthesis regulated by NFYA on malignant progression of breast cancer2020
    • Author(s)
      Chihiro Ueki, Goki Tsujimoto, Susumu Kohno, Chiaki Takahashi, Nobuhiro Okada
    • Organizer
      第43回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] Antitumor effect of gluconeogenesis induced by NFYA2020
    • Author(s)
      Goki Tsujimoto, Chiaki Takahashi, Nobuhiro Okada
    • Organizer
      第79回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] Akt dysregulation by loss of PHLDA3 is an important determinant of pancreatic neuroendocrine tumor progression.2020
    • Author(s)
      Yu Chen, Sadahiro Iwabuchi, Tohru Kiyono, Shigeyuki Magi, Yasuhito Arai, Akihiko Yokoyama, Mariko Okada, Shinichi Hashimoto, Kentaro Semba, Rieko Ohki.
    • Organizer
      第79回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] NFYA splicing variant regulates the malignant progression of breast cancer2020
    • Author(s)
      Nobuhiro Okada, Goki Tsujimoto, Kiyotsugu Yoshikawa, Chiaki Takahashi
    • Organizer
      第79回日本癌学会学術総会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] Developmentof an injectable water-soluble anticancer drug CMG for oxaliplatin-resistantcolorectal cancer with KRAS mutation2019
    • Author(s)
      Kakeya, H, Kishimoto, A., Umeta, H., Imaizumi, A., Kanai, M.
    • Organizer
      31th EORTC-NCI-AACR Symposium: InternationalConference on Molecular Targets and Cancer Therapeutics
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-17H06401

  • [Presentation] ホヤ脊索管形成の制御機構のケミカルバイオロジー2019
    • Author(s)
      井本正哉
    • Organizer
      日本農芸化学会　2019年度大会（東京）
    • Invited
    • Data Source
      KAKENHI-PLANNED-17H06401

  • [Presentation] Divergent Synthesis of Skeletally Distinct Alkaloidal Scaffolds via Zn(OTf)2-mediated Alkyne Activation2019
    • Author(s)
      Sadaiwa Yorimoto ; Yoshiaki Tsunekawa, Tomoya Ichino, Akira Tsubouchi, Satoshi Maeda, Hiroki Oguri
    • Organizer
      第99日本化学会春季年会
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] ケミカルバイオロジーで挑むホヤの脊索管形成機構解析2019
    • Author(s)
      Masaya Imoto
    • Organizer
      先端モデル動物支援プラットフォーム成果発表会2018
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02099

  • [Presentation] Formycin A selectively induced apoptosis in castration-resistant prostate cancer2019
    • Author(s)
      Masaya Imoto, Hiroshi Hongo, Takeo Kosaka, Mototsugu Oya
    • Organizer
      日本癌学会
    • Data Source
      KAKENHI-PROJECT-18H02099

  • [Presentation] Proof of concept for claudin-2-directed cancer therapy by using a monoclonal antibody that recognizes the extracellular loop domain of claudin-22019
    • Author(s)
      Hashimoto Y, Hata T, Tada M, Iida M, Watari A, Okada Y, Doi T, Kuniyasu H, Yagi K, Tachibana K, Kondoh M
    • Organizer
      2019 Controlled Release Society Annual Meeting & Exposition
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] Characteristics of subjective visual vertical in patients with unilateral spatial neglect2019
    • Author(s)
      Kimihiko Mori, Kae Nakamura, Shingo Hashimoto, Masanori Wakida, Kimitaka Hase
    • Organizer
      The 42nd annual meeting of the Japan Neuroscience Society
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] Symposia20 "Frontier in Molecular Target Therapy of Cancer": Developmentof a water-soluble prodrug CMG which inhibits proteasome activity throughDYRK2 dependent manner.2019
    • Author(s)
      Kanai, M., Kishimoto, A., Umeta, H., Imaizumi, A., Kakeya, H.
    • Organizer
      The 78th Annual Meeting of the Japanese CancerAssociation
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-17H06401

  • [Presentation] Analysis of the regulatory mechanism underlying brain tumor-initiating cell proliferation by MIF2019
    • Author(s)
      Ohta S, Morimoto Y, Tokumitsu A, Sone T, Sakamoto A, Toda M, Kawakami Y, Okano H
    • Organizer
      Neuro2019
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] Developmentof an innovative water-soluble anticancer drug, curcumin mono-beta-D-glucuronide(CMG)2019
    • Author(s)
      Hideaki Kakeya, Nobuaki Takahashi, Atsuhiro Kishimoto, Atsushi Imaizumi, Masashi Kanai
    • Organizer
      The 1st International Symposium on Chemical Communication (ISCC2019, Tokyo)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-17H06401

  • [Presentation] Chemical genomic analysis on autophagic regulation mechanism in human lung cancer A549 cells2018
    • Author(s)
      片浦哲志, 井本正哉
    • Organizer
      30th EORTC-NCI-AACR Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] Functional analysis of the novel WASP mutation resulting in X-linked congenital neutropenia2018
    • Author(s)
      Masayuki Kobayashi, Chanda Bidisha, Muneyoshi Futami., Mizuho Yamashita, Mitsuhiro Hirano, Kazuaki Yokoyama, Yoichi Imai, Eigo Yusa, Rui Yamaguchi, Seiya Imoto, Satoru Miyano, Arinobu Tojo
    • Organizer
      80th annual meeting of the JSH
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] Biomarker-based Screening Identified BET inhibitor JQ1 as a Neuroprotective Compound for Parkinson’s Disease2018
    • Author(s)
      Tetsushi Kataura, Shinji Saiki, Nobutaka Hattori, Masaya Imoto
    • Organizer
      第9回日韓ケミカルバイオロジーシンポジウム
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02099

  • [Presentation] Clinicopathological Analyses of 17 Cases of XpllTranslocation Renal Cell Carcinomas2018
    • Author(s)
      Mitsuko Furuya, Masaya Baba, Ikuma Kato, Tsunenori Kondo, Yoji Nagashima, Takao Kamai, Toshinari Yamasaki, Osamu Ogawa, Koushiro Nishimoto, Msafumi Koyama, Tomomi Kamba, Takanobu Motoshima, Masatoshi Eto
    • Organizer
      第77回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] がん細胞の特性を標的とする阻害剤の化学生物学的研究2018
    • Author(s)
      井本正哉
    • Organizer
      日本農芸化学会　2018年度第1回 関東支部例会（神奈川）
    • Invited
    • Data Source
      KAKENHI-PLANNED-17H06401

  • [Presentation] Biomarker-based screening identified BET inhibitor JQ1 as a neuroprotective compound for Parkinson's disease2018
    • Author(s)
      片浦哲志, 斉木臣二, 服部信孝, 井本正哉
    • Organizer
      The 9th Japan-Korea Chemical Biology Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] Chemical genomic analysis on autophagic regulation mechanism in human lung cancer A549 cells2018
    • Author(s)
      T. Kataura, M. Imoto
    • Organizer
      EORTC NCI AACR 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02099

  • [Presentation] バイオマーカーを指標とするパーキンソン病治療薬の探索とBET阻害剤JQIによる神経保護活性2018
    • Author(s)
      片浦哲志, 斉木臣二, 服部信孝, 井本正哉
    • Organizer
      日本ケミカルバイオロジー学会第13年会
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] Development of a syntheticwater-soluble curcumin mono-beta-D-glucuronide (CMG), as an innovativeanticancer prodrug targeting KRAS-NF-kappaB signaling pathway2018
    • Author(s)
      Hideaki Kakeya, Atsuhiro Kishimoto, Atsushi Imaizumi, Masashi Kanai
    • Organizer
      30th EORTC-NCI-AACRSymposium: International Conference on Molecular Targets and Cancer Therapeutics (Dublin)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-17H06401

  • [Presentation] Expression of claudin 1 and 4 in renal cell carcinoma2018
    • Author(s)
      Owari T, Kishi S, Fujiwara-Tani R. Mori S, Miyake M, Nakai Y, Kondou M, Fujimoto H, Kuniyasu H
    • Organizer
      77th Annual Meeting of Japanese Association for Cancer
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] Predicting non-responders to the steroid combination therapy in very severe Kawasaki disease2018
    • Author(s)
      Yoshikane Y, Hashimoto J, Miyamaoto T, Hirose S, Ogawa A
    • Organizer
      12th Interrnational Kawasaki Disease Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] がん細胞の特性を標的とする阻害剤の化学生物学的研究2018
    • Author(s)
      井本正哉
    • Organizer
      日本農芸化学会　2018年度第1回 関東支部例会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02099

  • [Presentation] ホヤ脊索管形成機構に挑むケミカルバイオロジー2018
    • Author(s)
      井本正哉
    • Organizer
      （独）日本学術振興会 産学協力研究委員会第170委員会・第189委員会 合同シンポジウム （東京）
    • Invited
    • Data Source
      KAKENHI-PLANNED-17H06401

  • [Presentation] NFkB inhibitors as a novel therapeutic agent in the acute phase of Kawasaki disease2018
    • Author(s)
      Yoshikane Y, Koga M, Bhatnagar R, Cho T, Haraoka S, Hashimoto J, Miyamoto T, Hirose S, Ogawa A
    • Organizer
      American Heart Association Scientific Sessions 2018
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] バイオマーカーを指標とするパーキンソン病治療薬の探索とBET阻害剤JQ1による神経保護活性2018
    • Author(s)
      片浦哲志、斉木臣二、服部信孝、井本正哉
    • Organizer
      日本ケミカルバイオロジー学会　第13回年会
    • Data Source
      KAKENHI-PROJECT-18H02099

  • [Presentation] Change in Electromyographic Patterns After Leg Amputation in the Cricket2018
    • Author(s)
      D. Owaki, Y. Sugimoto, A. Ishiguro and H. Aonuma
    • Organizer
      International Congress for Neuroethology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] Synaptopathies associated with loss of MDGAs2018
    • Author(s)
      Steven Connor, Ina Ammendrup-Johnsen, Yasushi Kishimoto, Parisa Karimi Tari, Vedrana Cvetkovska, Takashi Harada, Daiki Ojima, Tohru Yamamoto, Yu Tian Wang, Ann Marie Craig
    • Organizer
      17th Annual Molecular and Cellular Cognition Society Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] ケミカルゲノミクスによるオートファジー制御機構の解析2018
    • Author(s)
      片浦哲志、井本正哉
    • Organizer
      先端モデル動物支援プラットフォーム成果発表会
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] 微生物間化学コミュニケーションの理解と有用生物活性リガンドの開発2018
    • Author(s)
      掛谷秀昭, 西村慎一, 倉永健史, 野中元裕, 井本正哉
    • Organizer
      新学術領域研究「化学コミュニケーションのフロンティア」・第3回公開シンポジウム（東京）
    • Data Source
      KAKENHI-PLANNED-17H06401

  • [Presentation] パーキンソン病バイオマーカーを指標とする新規治療薬シードの探索2018
    • Author(s)
      片浦哲志, 井本正哉
    • Organizer
      第9回スクリーニング学研究会
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] Synthetic lethal killing of β-catenin mutant cancer cells by small molecules2017
    • Author(s)
      Masaya Imoto
    • Organizer
      3rd KRIBB-RIKEN Chemical Biology Joint Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-17H06401

  • [Presentation] シスプラチン持続暴露によるEMT誘導機構の解析2017
    • Author(s)
      田代悦、井本正哉
    • Organizer
      第21回日本がん分子標的治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-15H03116

  • [Presentation] 細胞内ビリルビン量を指標とするパーキンソン病治療薬の探索2017
    • Author(s)
      片浦哲志、斉木臣二、井本正哉
    • Organizer
      先端モデル動物支援プラットフォーム若手支援技術講習会
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] An easy and high efficient technique for mouse genome manipulation by electroporation.2017
    • Author(s)
      Michihiko Sugimoto, Daisuke Ariyasu, Kei-ichiro Ishiguro, Shingo Ito, Kimi Araki.
    • Organizer
      2017 ASMRA & AMPC meeting.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] Synthetic lethal killing of b-catenin mutant cancer cells by small molecules2017
    • Author(s)
      井本正哉
    • Organizer
      3rd KRIBB-RIKEN Chemical Biology Joint Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] Synthetic lethal killing of b-catenin mutant cancer cells by small molecules2017
    • Author(s)
      井本正哉
    • Organizer
      3rd KRIBB-RIKEN Chemical Biology Joint Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H03116

  • [Presentation] シスプラチン持続暴露によるEMT誘導機構の解析2017
    • Author(s)
      田代悦、井本正哉
    • Organizer
      第21回日本がん分子標的治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] 細胞形態・表現型解析による分子プロファイリング2017
    • Author(s)
      井本正哉
    • Organizer
      先端モデル動物支援プラットフォーム平成29年度若手支援技術講習会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] Screening of the compounds that modulate cellular bilirubin level in hepatocellular carcinoma HepG2 cells2017
    • Author(s)
      片浦哲志、井本正哉
    • Organizer
      The AACR-NCI-EORTC International Conference on "Molecular Targets and Cancer Therapeutics : Discovery, Biology, and Clinical Applications 2017"
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] Screening of the compounds that modulate cellular bikirubin level in hepatocellular carcinoma HepG2 cells2017
    • Author(s)
      片浦哲志、井本正哉
    • Organizer
      AACR-NCI-EORTC International Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H03116

  • [Presentation] βカテニン変異がん細胞に合成致死を誘導する化合物の探索2017
    • Author(s)
      井本正哉
    • Organizer
      第76回日本癌学会学術総会
    • Invited
    • Data Source
      KAKENHI-PLANNED-17H06401

  • [Presentation] 謎解きと宝探しの天然物ケミカルバイオロジー2017
    • Author(s)
      井本正哉
    • Organizer
      第52回天然物化学談話会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] 謎解きと宝探しの天然物ケミカルバイオロジー2017
    • Author(s)
      井本正哉
    • Organizer
      第52回天然物化学談話会
    • Invited
    • Data Source
      KAKENHI-PLANNED-17H06401

  • [Presentation] Screening of the compounds that modulate cellular bilirubin level in hopatocellular carcinoma HepG2 cells2017
    • Author(s)
      片浦哲志、井本正哉
    • Organizer
      AACR-NCI-EORTC International Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] 謎解きと宝探しの天然物ケミカルバイオロジー2017
    • Author(s)
      井本正哉
    • Organizer
      第52回天然物化学談話会
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H03116

  • [Presentation] Mitochondrial uncoupler exerts a synthetic lethal effect against beta-catenin mutant tumor cells2017
    • Author(s)
      井本正哉
    • Organizer
      Asian Chemical Biology Initiative 2017 Ho Chi Minh Meeting
    • Place of Presentation
      Ho Chi Minh （Vietnam）
    • Year and Date
      2017-01-21
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H03116

  • [Presentation] β-catenin変異型がん細胞選択的に細胞死を誘導する化合物の探索2016
    • Author(s)
      池田拓慧、田代悦、井本正哉
    • Organizer
      日本農芸化学会2016年度大会
    • Place of Presentation
      札幌コンベンションセンター（北海道・札幌市）
    • Year and Date
      2016-03-29
    • Data Source
      KAKENHI-PROJECT-15H03116

  • [Presentation] ミトコンドリア脱共役剤ノナクチンによるβ-catenin変異がんに対する合成致死誘導2016
    • Author(s)
      四方雄貴、木我真基、田代悦、井本正哉
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜（神奈川県・横浜市）
    • Year and Date
      2016-10-06
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H03116

  • [Presentation] シスプラチン耐性細胞におけるROCKによるE-cadherin発現制御2016
    • Author(s)
      田代悦、今辻沙也佳、井本正哉
    • Organizer
      日本癌学会
    • Place of Presentation
      パシフィコ横浜（神奈川県・横浜市）
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-26350974

  • [Presentation] メラノーマ治療薬として開発されたMEK阻害剤の大腸がん治療薬としての可能性2016
    • Author(s)
      四方雄貴、木我真基、田代悦、井本正哉
    • Organizer
      日本薬学会第136回年会
    • Place of Presentation
      パシフィコ横浜（神奈川県・横浜市）
    • Year and Date
      2016-03-27
    • Data Source
      KAKENHI-PROJECT-15H03116

  • [Presentation] Targeting distant metastasis of colorectal cancer with a combination of anti-claudin-4 antibody2016
    • Author(s)
      Fujiwara R, Luo Y, Sasaki T, Nishiguchi Y, Ohmori H, Hashimoto Y, Kondo M, Kuniayasu H
    • Organizer
      76th Annual Meeting of Japanese Association for Cancer
    • Place of Presentation
      バシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] ホルモン療法抵抗性前立腺がんに対する天然物創薬研究2016
    • Author(s)
      齋藤駿、藤巻貴宏、田代悦、五十嵐康弘、井本正哉
    • Organizer
      日本薬学会第136回年会
    • Place of Presentation
      パシフィコ横浜（神奈川県・横浜市）
    • Year and Date
      2016-03-28
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Presentation] 合成致死を利用したβ-catenin変異がんに対する治療薬シードの探索2016
    • Author(s)
      四方雄貴、木我真基、田代悦、井本正哉
    • Organizer
      第20回日本がん分子標的治療学会学術集会
    • Place of Presentation
      別府国際コンベンションセンター（大分県・別府市）
    • Year and Date
      2016-05-31
    • Data Source
      KAKENHI-PROJECT-15H03116

  • [Presentation] 新規発光物質の開発を目的としたホタルルシフェリンアナログの合成と活性評価2016
    • Author(s)
      井岡秀二、斉藤毅、岩野智、鈴木孝治、井本正哉、西山繁
    • Organizer
      日本化学会第96回春季年会（2016)
    • Place of Presentation
      同志社大学（京都府・京都市）
    • Year and Date
      2016-03-24
    • Data Source
      KAKENHI-PROJECT-15H03116

  • [Presentation] Cisplatin持続暴露によるEMT誘導機構2016
    • Author(s)
      今辻紗也佳、大嶽弘之、奈良部進、田代悦、井本正哉
    • Organizer
      日本農芸化学会2016年度大会
    • Place of Presentation
      札幌コンベンションセンター（北海道・札幌市）
    • Year and Date
      2016-03-29
    • Data Source
      KAKENHI-PROJECT-26350974

  • [Presentation] MEK阻害剤はベータカテニン変異細胞選択的にアポトーシスを誘導する2016
    • Author(s)
      井本正哉
    • Organizer
      第68回日本細胞生物学会大会
    • Place of Presentation
      京都テルサ テルサホール（京都府・京都市）
    • Year and Date
      2016-06-17
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H03116

  • [Presentation] 放線菌由来新規アンドロゲン受容体アンタゴニスト Antarlide 類の単離・構造決定及び生物活性2015
    • Author(s)
      齋藤駿、藤巻貴宏、田代悦、五十嵐康弘、井本正哉
    • Organizer
      第57回天然有機化合物討論会
    • Place of Presentation
      神奈川県民ホール（神奈川県・横浜市）
    • Year and Date
      2015-09-10
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Presentation] Chemistry and biology of natural products that modulate cellular responses2015
    • Author(s)
      Masaya Imoto
    • Organizer
      SIBM Natural Products 2015
    • Place of Presentation
      San Diego, CA USA
    • Year and Date
      2015-01-12
    • Invited
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Presentation] 抗がん剤耐性とEMTの関係に着目したMET誘導物質の探索系構築2015
    • Author(s)
      田代悦，大嶽弘之，奈良部進，井本正哉
    • Organizer
      日本農芸化学会
    • Place of Presentation
      岡山大学 津島キャンパス（岡山県岡山市）
    • Year and Date
      2015-03-27
    • Data Source
      KAKENHI-PROJECT-26350974

  • [Presentation] エストロゲン受容体制御分子BIG3を標的とした新規ER陽性乳がん治療法2015
    • Author(s)
      吉丸哲郎、小松正人、田代　悦、長田裕之、井本正哉、豊國伸哉、三好康雄、笹　三徳、片桐豊雅
    • Organizer
      第７４回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場、愛知県名古屋市
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Presentation] Identification of licopyranocoumarin and glycyrurol from herbal medicines as neuroprotective compounds for parkinson's disease2015
    • Author(s)
      M.Imoto, T.Fujimaki, S.Saiki, E.Tashiro, D.Yamada, N.Hattori
    • Organizer
      PACIFICHEM 2015
    • Place of Presentation
      ホノルル（米国）
    • Year and Date
      2015-12-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H03116

  • [Presentation] 生体内フリーラジカルの検出を目的とした新規ホタルルシフェリンアナログの開発2015
    • Author(s)
      井岡秀二、斉藤毅、岩野智、牧昌次郎、丹羽治樹、井本正哉、西山繁
    • Organizer
      日本ケミカルバイオロジー第10回年会
    • Place of Presentation
      東北大学川内キャンパス（宮城県・仙台市）
    • Year and Date
      2015-06-11
    • Data Source
      KAKENHI-PROJECT-15H03116

  • [Presentation] 微生物由来天然化合物の治療薬シードへの展開2015
    • Author(s)
      井本正哉、田代悦
    • Organizer
      日本農芸化学会2015年度大会
    • Place of Presentation
      岡山大学 津島キャンパス（岡山県岡山市）
    • Year and Date
      2015-03-29
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Presentation] カリウムイオノフォアであるNonactinはβ-catenin変異がん選択的に細胞死を誘導する2015
    • Author(s)
      四方雄貴、田代悦、井本正哉
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場（愛知県・名古屋市）
    • Year and Date
      2015-10-09
    • Data Source
      KAKENHI-PROJECT-15H03116

  • [Presentation] β-catenin変異型がん細胞選択的に細胞死を誘導する化合物の探索2015
    • Author(s)
      池田拓慧、四方雄貴、田代悦、井本正哉
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場（愛知県・名古屋市）
    • Year and Date
      2015-10-09
    • Data Source
      KAKENHI-PROJECT-15H03116

  • [Presentation] Association of an EPAS1 gene polymorphism with susceptibility to lung adenocarcinoma in female Japanese non-smokers2015
    • Author(s)
      Hidetaka Eguchi, Shinichi Iwamoto, Yumi Nishio, Andica Chandra Putra, Hiroshi Fuchita, Miki Ohe, Akihisa Sutani, Takashige Kuraki, Keiko Hiyama, Isao Murakami, Keiji Tanimoto, Takeshi Isobe
    • Organizer
      第25回日本疫学会学術総会
    • Place of Presentation
      ウインクあいち(愛知県・名古屋市)
    • Year and Date
      2015-01-23
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Presentation] CDDP耐性細胞におけるTGF-β受容体阻害剤によるMET誘導2015
    • Author(s)
      今辻紗也佳、田代悦、井本正哉
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場（愛知県・名古屋市）
    • Year and Date
      2015-10-09
    • Data Source
      KAKENHI-PROJECT-26350974

  • [Presentation] Isolation and biological activities of novel androgen receptor antagonist produced by Streptomyces2015
    • Author(s)
      S.Saito, T.Fujimaki, E.Tashiro, Y.Igarashi, M.Imoto
    • Organizer
      PACIFICHEM 2015
    • Place of Presentation
      ホノルル（米国）
    • Year and Date
      2015-12-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Presentation] ケミカルジェネティクスによるホヤ脊索管形成機構の解析2014
    • Author(s)
      溝谷優治、堀田耕司、岡浩太郎、柴小菊、稲葉一男、鈴木麻友、田代悦、井本正哉
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      国立京都国際会館（京都府京都市）
    • Year and Date
      2014-10-18
    • Data Source
      KAKENHI-PROJECT-25560419

  • [Presentation] Xanthohumol impairs autophagosome maturation through direct inhibition of Valosin-containing protein2014
    • Author(s)
      井本正哉
    • Organizer
      RIKEN-Max Planck Joint Research Center for Systems Chemical Biology 3rd Annual Symposium
    • Place of Presentation
      Schloss Ringberg, Germany
    • Year and Date
      2014-05-22
    • Invited
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Presentation] Establishment of a New Detection System for the Dimerization of IRE1a Using a BiFC Assay2014
    • Author(s)
      Etsu Tashiro, Satoko Shinjo, Masaya Imoto
    • Organizer
      7th The Japan-Korea Chemical Biology Symposium
    • Place of Presentation
      韓国チェジュ島
    • Year and Date
      2014-02-10
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Presentation] 化合物活性予測のための遺伝子発現データベース構築2014
    • Author(s)
      田代悦、大嶽弘之、井本正哉
    • Organizer
      文科省新学術領域研究・がん支援「化学療法基盤支援活動」第三回シンポジウムアカデミアからの抗がん剤創薬に向けて-天然物の有効利用
    • Place of Presentation
      万国津梁館(沖縄県・名護市)
    • Year and Date
      2014-05-12
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Presentation] The association of alcohol intake with serum lipid profile and its modification by ADH1B and ALDH2 polymorphisms : J-MICC Study2014
    • Author(s)
      Sasakabe T, Guang Y, Naito M, Morita E, Kawai S, Okada R, Tamura T, Nakagawa H, Suma S, Fukuda N, Sugimoto Y, Wakai K, Hamajima N
    • Organizer
      The 20th IEA World Congress of Epidemiology
    • Place of Presentation
      Anchorage, Alaska, U.S.A.
    • Year and Date
      2014-08-17
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Presentation] 種々の化合物によるUPR関連遺伝子群発現挙動の解析2014
    • Author(s)
      田代悦、新荘聡子、溝谷優治、井本正哉
    • Organizer
      日本農芸化学会
    • Place of Presentation
      明治大学生田キャンパス
    • Year and Date
      2014-03-28
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Presentation] HDAC阻害剤SAHAによるMET誘導2014
    • Author(s)
      田代悦，井本正哉
    • Organizer
      日本がん分子標的治療学会
    • Place of Presentation
      仙台市情報・産業プラザ（宮城県仙台市）
    • Year and Date
      2014-06-26
    • Data Source
      KAKENHI-PROJECT-26350974

  • [Presentation] Isoflavones in Japanese and Caucasian men with prostate cancer in Hawaii2014
    • Author(s)
      Fukagai T, Akaza H, Ogawa Y, Carlile R, Namiki T, Lederer JL, Maskarinec G, Tsuji H, Moriyama K, Fujimoto K, Hirao Y, Namiki M
    • Organizer
      2014 Genitourinary Cancer Symposium
    • Place of Presentation
      San Francisco, USA
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Presentation] Distinct patterns of RHOA mutations in Adult T-Cell Leukemia/Lymphoma and peripheral T-Cell lymphomas2014
    • Author(s)
      Nagata Y, Enami T, Sakata-Yanagimoto M, Kataoka K, Kitanaka A, Sato A, Shiraishi Y, Chiba K, Tanaka H, Shiozawa Y, Yoshizato T, Kon A, Yoshida K, Sanada M, Ishiyama K, Miyawaki S, Ishii R, Nureki O, Miyano S, Shimoda K, Watanabe T, Chiba S, Ogawa S
    • Organizer
      第76回日本血液学会学術集会
    • Place of Presentation
      大阪国際会議場(大阪府・大阪市)
    • Year and Date
      2014-11-01
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Presentation] Dysphagia and dietary intake of Japanese adults : the Shizuoka area in a Japanese multi-institutional collaborative cohort study2014
    • Author(s)
      Naito M, Wakai K, Kawai S, Nakagawa H, Tamura T, Suma S, Sugimoto Y, Fukuda N, Sasakbe T, Okada R, Morita E, Asai Y, Mori A, Hamajima N
    • Organizer
      The 20th IEA World Congress of Epidemiology
    • Place of Presentation
      Anchorage, Alaska, U.S.A.
    • Year and Date
      2014-08-19
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Presentation] Novel Biological Effects and Distinct Patterns of Rhoa Mutations in Adult T-Cell Leukemia/Lymphoma and Angioimmunoblastic T Cell Lymphoma2014
    • Author(s)
      Nagata Y, Enami T, Kontani K, Kataoka K, Sakata-Yanagimoto M, Kitanaka A, Sato A, Shiraishi Y, Chiba K, Tanaka H, Shiozawa Y, Yoshizato T, Kon A, Yoshida K, Sanada M, Ishiyama K, Miyawaki S, Ishii R, Nureki O, Miyano S, Shimoda K, Watanabe T, Katada T, Chiba S, Ogawa S
    • Organizer
      56th of ASH Annual Meeting and Exposition
    • Place of Presentation
      Moscone Center, San Francisco, U.S.A.
    • Year and Date
      2014-12-07
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Presentation] Significant associations of abdominal obesity with LYPLAL1 polymorphism (rs4846567) among a general Japanese population : a cross-sectional study2014
    • Author(s)
      Takashi T, Morita E, Kawai S, Sasakabe T, Fukuda N, Sugimoto Y, Suma S, Mokuno J, Nakagawa H, Hishida A, Okada R, Naito M, Hamajima N, Wakai K
    • Organizer
      The 20th IEA World Congress of Epidemiology
    • Place of Presentation
      Anchorage, Alaska, U.S.A.
    • Year and Date
      2014-08-19
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Presentation] Xanthohumol Impairs Autophagosome Maturation through Direct Inhibition of Valosin-Containing Protein2014
    • Author(s)
      Masaya Imoto
    • Organizer
      Riken-MaxPlanck 3rd Annual Symposium
    • Place of Presentation
      Kreuth／German
    • Year and Date
      2014-05-23
    • Invited
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Presentation] Comparative Analysis of the Expression Patterns of UPR-Target Genes Caused by UPR-Inducing Compounds2014
    • Author(s)
      Etsu Tashiro, Satoko Shinjo, Yuji Mizotani, and Masaya Imoto
    • Organizer
      RIKEN-Max Planck Joint Research Center for Systems Chemical Biology 3rd Annual Symposium
    • Place of Presentation
      Schloss Ringberg ドイツ
    • Year and Date
      2014-05-22
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Presentation] 5-リポキシゲナーゼ/CysLT1シグナルによるがん細胞遊走促進機構解析2014
    • Author(s)
      井本正哉
    • Organizer
      第23回日本がん転移学会学術集会・総会
    • Place of Presentation
      金沢市文化ホール（石川県金沢市）
    • Year and Date
      2014-07-10
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Presentation] 新規アンドロゲン受容体アンタゴニストの探索と薬理活性評価2014
    • Author(s)
      齋藤駿、藤巻貴宏、榊原康文、田代悦、井本正哉
    • Organizer
      日本ケミカルバイオロジー学会第9回年会
    • Place of Presentation
      大阪大学 大阪大学会館（大阪府豊中市）
    • Year and Date
      2014-06-13
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Presentation] 癌の代謝解析による薬剤標的探索2013
    • Author(s)
      井本正哉
    • Organizer
      がんと代謝シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2013-01-08
    • Invited
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Presentation] BiFC法を利用した新規IRE1a活性化阻害剤探索系の構築 Establishment of a new screening system for the inhibitor of IRE1a activation using a BiFC assay2013
    • Author(s)
      田代悦、井本正哉
    • Organizer
      日本がん分子標的治療学会
    • Place of Presentation
      京都国際会議場
    • Year and Date
      2013-06-13
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Presentation] Metabolomic Identification of the Target of Microbial Probes Modulating Cellular Responses2013
    • Author(s)
      Masaya Imoto,
    • Organizer
      , The 2nd International Symposium on Chemical Biology of Natural Products.
    • Place of Presentation
      Yokohama Japan
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-23102001

  • [Presentation] ヒト大腸がん細胞LoVoにおける、EGF誘導体E-cad-herin発現抑制機構の解析2013
    • Author(s)
      大嶽弘之、邊見静香、久田明里、小林大貴、田代悦、井本正哉
    • Organizer
      日本農芸化学会2013年度大会
    • Place of Presentation
      仙台
    • Year and Date
      2013-03-26
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Presentation] Establishment of a New Detection System for the Dimerization of IRE1a Using a BiFC Assay2013
    • Author(s)
      Satoko Shinjo, Etsu Tashiro, Masaya Imoto
    • Organizer
      RIKEN-Max Planck-Join Research Center for 2nd Systems Chemical Biology The Symposium
    • Place of Presentation
      理研(和光)
    • Year and Date
      2013-04-16
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Presentation] BiFC法によるIRE1a二量体化検出法の構築 Establishment of a new detection system for the dimerization of IRE1a by BiFC assay2013
    • Author(s)
      新荘聡子、田代悦、井本正哉
    • Organizer
      日本ケミカルバイオロジー学会
    • Place of Presentation
      東京医科歯科大学
    • Year and Date
      2013-06-20
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Presentation] “Chemistry and biology of Xanthohumol, an inhibitor of Valosin-Containing Protein.”2013
    • Author(s)
      井本正哉
    • Organizer
      EMBO Workshop【AAA+ proteins: from mechanism and disease to targets】
    • Place of Presentation
      Germany・Neuss
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Presentation] The Efficacy and Safety of Mogamulizumab (KW-0761) in Multicenter Phase II Study for Patients with Relapsed Peripheral or Cutaneous T-Cell Lymphoma (abs 041)2013
    • Author(s)
      Ueda R, Ogura M, Ishida T, Hatake K, Taniwaki M, Ando K, Tobinai K, Fujimoto K, Yamamoto K, Miyamoto T, Uike N, Tanimoto M, Tsukasaki K, Ishizawa K, Suzumiya J, Inagaki H, Tamura K, Akinaga S, Tomonaga M.
    • Organizer
      12th International Conference on Malignant Lymphoma.
    • Place of Presentation
      Lugano, Switzerland.
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Presentation] BiFC法によるIRE1a二量体検出法の構築2013
    • Author(s)
      田代悦、新荘聡子、井本正哉
    • Organizer
      日本農芸化学会関東支部2013年度支部大会
    • Place of Presentation
      慶應義塾大学
    • Year and Date
      2013-11-22
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Presentation] UPR誘導剤によるUPR関連遺伝子発現パターンの比較解析 Comparative analysis of the expression patterns of UPR-target genes caused by UPR-inducing compounds2013
    • Author(s)
      田代悦、井本正哉
    • Organizer
      日本癌学会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2013-10-05
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Presentation] Applications of Cryopreserved Mouse Oocytes for In vitro Fertilization Using Fresh， Cold-stored and Frozen Sperm2013
    • Author(s)
      Ishizuka,Y., Yoshimoto,H., Sakoh, K., Nakao, S., Horikoshi, Y., Hirose, Y., Takeuji, S., Sakai, Y., Maeda, Y., Hachiya, M., Mukunoki, A., Takeo, T., Nakagata,N.
    • Organizer
      ANZLAA conference
    • Place of Presentation
      Perth, Australia
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Presentation] 新たなアンドロゲンアンタゴニストの検索のためのアプローチ2012
    • Author(s)
      藤巻貴宏、田代悦、井本正哉
    • Organizer
      第16回日本がん分子標的治療学会
    • Place of Presentation
      小倉
    • Year and Date
      2012-06-29
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Presentation] Senescence-associated secretory phenotypes (SASPs) promote obesity2012
    • Author(s)
      Ohtani, N, Yoshimoto, S, Loo, TM, Kanda, H, Sato, S, Ishikawa, Y, Hara. E.
    • Organizer
      associated hepatocarcinogenesis Keystone symposia
    • Place of Presentation
      Tokyo
    • Year and Date
      2012-10-25
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Presentation] Studies on the Signaling Pathway for Cancer Cell Migration by the Combination of Chemical Biology and Systems Biology2012
    • Author(s)
      Shigeyuki Magi, Etsu Tashiro, and Masaya Imoto
    • Organizer
      FOSBE 2012
    • Place of Presentation
      鶴岡
    • Year and Date
      2012-10-22
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Presentation] Drug Seed Generation from Natural Products2012
    • Author(s)
      Masaya Imoto
    • Organizer
      3rd MEXT-ARDA PROJECT Concluding Joint Seminar and JSPS-NRCT ASIAN CORE PROGRAM Joint Seminar
    • Place of Presentation
      Bangkok（Thailand）
    • Year and Date
      2012-08-26
    • Invited
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Presentation] Xanthohumolのautophagy制御機構解析2012
    • Author(s)
      金墻周平, 他6名、井本正哉
    • Organizer
      日本農芸化学会2012年度大会
    • Place of Presentation
      京都女子大学他(京都)
    • Year and Date
      2012-03-23
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Presentation] A Comparative Analysis of the Expression Patterns of UPR-Target Genes caused by UPR-inducing Compounds2012
    • Author(s)
      Etsu Tashiro, Satoko Shinjo, Yuji Mizotani, and Masaya Imoto
    • Organizer
      EMBO Conference -The Physiology of the ER
    • Place of Presentation
      Girona (Spain)
    • Year and Date
      2012-10-16
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Presentation] 種々の小分子化合物によるUPR関連遺伝子群発現挙動の解析2012
    • Author(s)
      田代悦、新荘聡子、溝谷優治、井本正哉
    • Organizer
      第7回小胞体ストレス研究会
    • Place of Presentation
      広島
    • Year and Date
      2012-11-09
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Presentation] Induction of cellular senescence in obesity2012
    • Author(s)
      Yoshimoto, S, Loo, TM, Kanda, H, Sato, S, Ishikawa, Y, Hara, E, Ohtani, N.
    • Organizer
      associated hepatic carcinogenesis Keystone symposia
    • Place of Presentation
      Dublin, Ireland
    • Year and Date
      2012-05-20
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Presentation] BiFC法によるIRE1二量体化検出法の構築2012
    • Author(s)
      新荘聡子、田代悦、井本正哉
    • Organizer
      日本分子生物学会
    • Place of Presentation
      福岡国際会議場
    • Year and Date
      2012-12-11
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Presentation] XBP1活性化阻害剤の探索と多発性骨髄腫治療薬への応用2012
    • Author(s)
      田代悦、李政樹、岩脇隆夫、飯田真介、井本正哉
    • Organizer
      新学術領域研究「天然物ケミカルバイオロジー:分子標的と活性制御」第2回若手研究者ワークショップ
    • Place of Presentation
      大阪大学中之島センター
    • Year and Date
      2012-10-30
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Presentation] Studies on the Signaling Pathway for Cancer Cell Migration by the Combination of Chemical Biology and Systems Biology2012
    • Author(s)
      Shigeyuki Magi, Etsu Tashiro, and Masaya Imoto
    • Organizer
      FOSBE 2012
    • Place of Presentation
      鶴岡
    • Year and Date
      2012-10-22
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Presentation] CysLT1シグナルはTiam1の発現制御を介してEGF刺激依存的細胞遊走を制御する2012
    • Author(s)
      間木重行、笠松誠人、竹本靖、小林大貴、田代悦、井本正哉
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      札幌
    • Year and Date
      2012-09-20
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Presentation] イノスタマイシンによるFGF受容体-1ゴルジ体蓄積機構の解析2011
    • Author(s)
      田代悦、張嘉峯、井本正哉
    • Organizer
      日本ケミカルバイオロジー学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Presentation] Quinotrierixin Inhibited Endoplasmic Reticulum Stress-Induced X-box Binding Protein 1 mRNA Splicing through Inhibition of Protein Synthesis2011
    • Author(s)
      Kohta Yamamoto, Etsu Tashiro, and Masaya Imoto
    • Organizer
      5th International Congress on Stress Responses in Biology and Medicine
    • Place of Presentation
      カナダ・ケベックシティ
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Presentation] Quinotrierixin Inhibited Endoplasmic Reticulum Stress-Induced X-box Binding Protein 1 mRNA Splicing through Inhibition of Protein Synthesis2011
    • Author(s)
      Kohta Yamamoto, Etsu Tashiro, and Masaya Imoto
    • Organizer
      5th International Congress on Stress Responses in Biology and Medicine
    • Place of Presentation
      カナダ・ケベック
    • Year and Date
      2011-08-22
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Presentation] Analysis of Machinery for Endoplasmic Reticulum Stress Response Induced by Small Molecular Compounds2011
    • Author(s)
      Satoko Shinjo, Etsu Tashiro, and Masaya Imoto
    • Organizer
      5th International Congress on Stress Responses in Biology and Medicine
    • Place of Presentation
      カナダ・ケベック
    • Year and Date
      2011-08-22
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Presentation] EGF刺激によるがん細胞遊走におけるCysLT1シグナリングの関与2011
    • Author(s)
      小林大貴、田代悦、井本正哉
    • Organizer
      第15回日本がん分子標的治療学会学術集会
    • Place of Presentation
      ホテル日航東京(東京)
    • Year and Date
      2011-06-24
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Presentation] イノスタマイシンによるFGF受容体-1ゴルジ体蓄積機構の解析 Studies on the mechanism of FGF receptor-1 accumulation in golgi apparatus by inostamycin2011
    • Author(s)
      田代悦、張嘉峯、井本正哉
    • Organizer
      日本ケミカルバイオロジー学会
    • Place of Presentation
      東京
    • Year and Date
      2011-05-24
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Presentation] イノスタマイシンによるFGF受容体-1ゴルジ体蓄積機構の解析2011
    • Author(s)
      田代悦、張嘉峯、井本正哉
    • Organizer
      日本ケミカルバイオロジー学会第6回年会
    • Place of Presentation
      東京工業大学(東京)
    • Year and Date
      2011-05-24
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Presentation] 新規MEK1/2阻害剤、SMK-17の抗腫瘍活性2011
    • Author(s)
      木我真基、中山綾子, 他、井本正哉
    • Organizer
      日本ケミカルバイオロジー学会第6回年会
    • Place of Presentation
      東京工業大学(東京)
    • Year and Date
      2011-05-24
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Presentation] Analysis of Machinery for Endoplasmic Reticulum Stress Response Induced by Small Molecular Compounds2011
    • Author(s)
      Satoko Shinjo, Etsu Tashiro, and Masaya Imoto
    • Organizer
      5th International Congress on Stress Responses in Biology and Medicine
    • Place of Presentation
      カナダ・ケベックシティ
    • Data Source
      KAKENHI-PROJECT-23510283

  • [Presentation] 新規アンドロゲンアンタゴニストの探索と薬理活性評価2011
    • Author(s)
      藤巻貴宏、鳥居健太郎, 他、井本正哉
    • Organizer
      日本ケミカルバイオロジー学会第6回年会
    • Place of Presentation
      東京工業大学(東京)
    • Year and Date
      2011-05-25
    • Data Source
      KAKENHI-PLANNED-23102006

  • [Presentation] Metabolomic identification of the target of the filopodia protrusion inhibitor glucopiericidin A2011
    • Author(s)
      Masaya Imoto
    • Organizer
      国際微生物学連合2011会議
    • Place of Presentation
      札幌コンベンションセンター(札幌)(招待講演)
    • Year and Date
      2011-09-07
    • Data Source
      KAKENHI-PROJECT-22310140

  • [Presentation] ケミカルシステムバイオロジーを用いた個別がん細胞の遊走制御機構解析2011
    • Author(s)
      間木重行、田代悦、井本正哉
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場(名古屋)
    • Year and Date
      2011-10-04
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Presentation] ケミカルシステムバイオロジーを用いた個別がん細胞の遊走制御機構解析2011
    • Author(s)
      間木重行、田代悦、井本正哉
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-10-04
    • Data Source
      KAKENHI-PROJECT-22651084

  • [Presentation] EGF刺激によるがん細胞遊走におけるCysLT1シグナリングの関与2011
    • Author(s)
      小林大貴、田代悦、井本正哉
    • Organizer
      第15回日本がん分子標的治療学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2011-06-24
    • Data Source
      KAKENHI-PROJECT-22310140