Seimiya Hiroyuki 清宮啓之

… Alternative Names

Researcher Number	50280623
Other IDs	https://orcid.org/0000-0003-3314-9736
Affiliation (Current)	2020: 公益財団法人がん研究会, がん化学療法センター分子生物治療研究部, 部長
Affiliation (based on the past Project Information) *help	2016 – 2020: 公益財団法人がん研究会, がん化学療法センター分子生物治療研究部, 部長 2018: 公益財団法人がん研究会, がん化学療法センター・分子生物治療研究部, 部長 2011 – 2016: 公益財団法人がん研究会, がん化学療法センター分子生物治療研究部, 部長 2015: 公益財団法人がん研究会, がん化学療法センター・分子生物治療研究部, 部長 2013: (公財)がん研, がん化療セ, 分子生物治療 … More
Review Section/Research Field	Principal Investigator Biological Sciences / Molecular biology / Tumor therapeutics / Medium-sized Section 50:Oncology and related fields / Molecular biology / Medical pharmacy / Clinical oncology / Tumor biology / Tumor diagnosis / Basic Section 50020:Tumor diagnostics and therapeutics-related / Science and Engineering … More Except Principal Investigator … More
Keywords	Principal Investigator がん / テロメア / タンキラーゼ / テロメラーゼ / 分子標的治療 / PARP / 阻害剤 / 分子標的 / DNA損傷 / ポリ(ADP-リボシル)化 … More Except Principal Investigator 抗癌剤耐性 / 分子標的 / テロメラーゼ / テロメア / 抗がん剤 / G-tail / P-糖タンパク / 耐性タンパク / 耐性遺伝子 / 耐性克服 / アポトーシス / 癌転移 / 癌移転 / テロメア維持機構 / 染色体外テロメア断片DNA / 不死化 / 癌診断 / hTERT / 癌診断法 / 制癌剤 / TRAP / HPA法 / テロメラーゼ遺伝子 / テロメラーゼ複合体 / 診断マーカー / 癌早期診断 / 細胞不死化 / 化合物 / 阻害剤 / スクリーニング / 研究支援 / データベース / ケミカルバイオロジー / 若手支援 / 国際研究者交流 / 遺伝子改変マウス / 病理形態学 / ゲノムコーホート研究 / 次世代分子解析技術 / アカデミア創薬 / ゲノム・エピゲノム解析支援 / 個別化がん予防 / 国際交流 / ATL発症予防 / 分子疫学コーホート研究 / がん化学予防 / ATL発がん機序 / ATL発症リスク / がん分子標的薬剤 / 前立腺がん / がん幹細胞 / RNAiスクリーニング / がん分子標的治療 / 分子標的治療 / 癌遺伝子 / テロメア結合タンパク質 / 老化 / telomere / telomere binding protein / telomerase / anticancer drug / モデル動物作製 / ゲノム編集 / 病理形態解析 / 生理機能解析 / 分子探索・プロファイリング / 分子プロファイリング / 分子探索・ブロファイリング / 行動解析 Less

Elucidating the functions of quadruplex nucleic acids by integrative molecular profiling of chemical signalsPrincipal InvestigatorOngoing
- Principal Investigator
  
  清宮啓之
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Japanese Foundation for Cancer Research
四重鎖核酸の動態攪乱に対するがん細胞選択的脆弱性の分子基盤Principal InvestigatorOngoing
- Principal Investigator
  
  清宮啓之
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  Japanese Foundation for Cancer Research
Optimization of cancer therapeutic strategies that target tankyrase-specific PARylationPrincipal InvestigatorOngoing
- Principal Investigator
  
  清宮啓之
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Japanese Foundation for Cancer Research
Integrative functional analysis of G-quadruplex nucleic acids by utilizing natural and synthetic chemical tool moleculesPrincipal InvestigatorOngoing
- Principal Investigator
  
  清宮啓之
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  Japanese Foundation for Cancer Research
非典型核酸形態が惹起するがん種横断的脆弱性の分子基盤と治療応用Principal InvestigatorOngoing
- Principal Investigator
  
  清宮啓之
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  Japanese Foundation for Cancer Research
Synthetic lethality-based identification of drug-sensitive genome profilesPrincipal Investigator
- Principal Investigator
  
  Seimiya Hiroyuki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Japanese Foundation for Cancer Research
先端モデル動物支援プラットフォームOngoing
- Principal Investigator(Support)
  
  今井浩三
- Project Period (FY)
  2016 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas ― Platforms for Advanced Technologies and Research Resources
- Research Institution
  The University of Tokyo
Regulation of cell motility by poly(ADP-ribosyl)ation and its application to overcoming cancer invasion and metastasisPrincipal Investigator
- Principal Investigator
  
  Seimiya Hiroyuki
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor therapeutics
- Research Institution
  Japanese Foundation for Cancer Research
Development of G-quadruplex ligands that target cancer stem cellsPrincipal Investigator
- Principal Investigator
  
  Seimiya Hiroyuki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Japanese Foundation for Cancer Research
Bioinformatics-based functional analysis of telomeric non-coding RNAPrincipal Investigator
- Principal Investigator
  
  SEIMIYA Hiroyuki
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor diagnosis
- Research Institution
  Japanese Foundation for Cancer Research
ポリ（ＡＤＰーリボシル）化による細胞の分裂と運動の制御Principal Investigator
- Principal Investigator
  
  清宮啓之
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Japanese Foundation for Cancer Research
Role of oncogenic factors and their cooperations in survival of prostate tumor-propagating cells
- Principal Investigator
  
  MASHIMA Tetsuo
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Clinical oncology
- Research Institution
  Japanese Foundation for Cancer Research
Scientific Support Programs for Cancer Research Grant-in-Aid for Scientific Research on Innovative Areas
- Principal Investigator
  
  IMAI Kohzoh, 中村祐輔
- Project Period (FY)
  2010 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  The University of Tokyo
Development of cancer molecular therapeutics that targets telomere-regulating factorsPrincipal Investigator
- Principal Investigator
  
  SEIMIYA Hiroyuki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Clinical oncology
- Research Institution
  Japanese Foundation For Cancer Research
Lipid metabolomics to analyze the mechanisms for cellular adaptation to tumor microenvironmentPrincipal Investigator
- Principal Investigator
  
  SEIMIYA Hiroyuki
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor biology
- Research Institution
  公益財団法人がん研究会
   Japanese Foundation For Cancer Research
Development of cancer molecular therapeutics directed to telomeres and cellular senescence svstemsPrincipal Investigator
- Principal Investigator
  
  SEIMIYA Hiroyuki
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Japanese Foundation For Cancer Research
がんの微小環境によるホルモン受容体制御と内分泌がんの生存機構Principal Investigator
- Principal Investigator
  
  清宮啓之
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Medical pharmacy
- Research Institution
  Japanese Foundation For Cancer Research
Multi-functions of tankyrase-1 in carcinogenesisPrincipal Investigator
- Principal Investigator
  
  SEIMIYA Hiroyuki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Molecular biology
- Research Institution
  Japanese Foundation For Cancer Research
染色体末端の維持機構を標的とした癌分子治療法の開発Principal Investigator
- Principal Investigator
  
  清宮啓之
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Japanese Foundation For Cancer Research
Elucidation of the consequence of telomere single-stand overhang, G-tail, in biology, and application to age-related disease
- Principal Investigator
  
  TAHARA Hidetoshi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hiroshima University
Development of an information-intensive basis for cancer chemotherapy
- Principal Investigator
  
  YAMORI Takao
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Japanese Foundation For Cancer Research
染色体末端の維持機構を標的とした癌分子治療法の開発Principal Investigator
- Principal Investigator
  
  清宮啓之
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Japanese Foundation For Cancer Research
タンキラーゼ1・TAB182の生理機能とその制御機構Principal Investigator
- Principal Investigator
  
  清宮啓之
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Molecular biology
- Research Institution
  Japanese Foundation For Cancer Research
タンキラーゼによるテロメア長制御機構とテロメラーゼ阻害剤による制癌Principal Investigator
- Principal Investigator
  
  清宮啓之
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Japanese Foundation For Cancer Research
タンキラーゼによるテロメア長制御機構とテロメラーゼ阻害剤による制癌Principal Investigator
- Principal Investigator
  
  清宮啓之
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Japanese Foundation For Cancer Research
タンキラーゼ・TAB182の生理機能とその制御機構Principal Investigator
- Principal Investigator
  
  清宮啓之
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Molecular biology
- Research Institution
  Japanese Foundation For Cancer Research
テロメラーゼ機能・テロメア維持機構の解明とその臨床応用
- Principal Investigator
  
  井出利憲
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Hiroshima University
テロメラーゼ阻害剤による制癌と癌細胞におけるテロメラーゼ活性制御機構Principal Investigator
- Principal Investigator
  
  清宮啓之
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Japanese Foundation For Cancer Research
白血病細胞におけるチロシンホスファターゼPTP-U2の発現調節と情報伝達Principal Investigator
- Principal Investigator
  
  清宮啓之
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Molecular biology
- Research Institution
  Japanese Foundation For Cancer Research
がん細胞の薬剤感受性と抵抗性の分子機構とその制御
- Principal Investigator
  
  鶴尾隆
- Project Period (FY)
  1994 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  The University of Tokyo

[Book] ゲノム解析に基づく新しい分子標的治療 : ゲノムワイドな解析および統合的解析による前立腺がん幹細胞の分子標的探索(「がん分子標的治療」)2015
- Author(s)
  馬島哲夫、清宮啓之
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-221S0001
[Book] 特集・制がん剤の分子標的スクリーニング成績「化学療法基盤情報支援班」報告‐制がん候補物質のスクリーニング成績・第15報『癌と化学療法オンライン』2013
- Author(s)
  矢守隆夫, 上原至雅, 深澤秀輔, 吉田稔, 井本正哉, 清宮啓之, 馬島哲夫, 水上民夫, 川田学, 長田裕之, 旦慎吾, 松浦正明, 掛谷秀昭, 冨田章弘.
- Publisher
  癌と化学療法社
- Data Source
  KAKENHI-PROJECT-221S0001
[Book] ノーベル賞をもたらしたテロメア研究と癌の診断・治療応用への期待、Surgery Frontier 202013
- Author(s)
  清宮啓之
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-24650639
[Book] 特集・制がん剤の分子標的スクリーニング成績化学療法基盤情報支援班報告-制がん候補物質のスクリーニング成績・第14報-2013
- Author(s)
  矢守隆夫, 上原至雅, 深澤秀輔, 吉田稔, 井本正哉, 清宮啓之, 水上民夫, 川田学, 長田裕之, 松浦正明.
- Publisher
  癌と化学療法社
- Data Source
  KAKENHI-PROJECT-221S0001
[Book] 癌細胞の不死化と難治性、臨牀と研究902013
- Author(s)
  清宮啓之
- Publisher
  大道学館出版部
- Data Source
  KAKENHI-PROJECT-24650639
[Book] 特集・制がん剤の分子標的スクリーニング成績「化学療法基盤情報支援班」報告-制がん候補物質のスクリーニング成績・第14報『癌と化学療法オンライン』2013
- Author(s)
  矢守隆夫, 上原至雅, 深澤秀輔, 吉田稔, 井本正哉, 清宮啓之, 水上民夫, 川田学, 長田裕之, 松浦正明.
- Publisher
  癌と化学療法社
- Data Source
  KAKENHI-PROJECT-221S0001
[Book] 特集・制がん剤の分子標的スクリーニング成績化学療法基盤支援活動報告-制がん候補物質のスクリーニング成績・第15報2013
- Author(s)
  矢守隆夫, 上原至雅, 深澤秀輔, 吉田稔, 井本正哉, 清宮啓之, 馬島哲夫, 水上民夫, 川田学, 長田裕之, 旦慎吾, 松浦正明, 掛谷秀昭, 冨田章弘
- Publisher
  癌と化学療法社
- Data Source
  KAKENHI-PROJECT-221S0001
[Book] がんと脂質代謝実験医学 302012
- Author(s)
  右田敏郎、馬島哲夫、清宮啓之
- Data Source
  KAKENHI-PROJECT-23501319
[Book] テロメアの維持と細胞の分裂寿命、「がん増殖と悪性化の分子機構」2012
- Author(s)
  清宮啓之(編者:宮澤恵二・伊東進)
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-24650639
[Book] 特集・制がん剤の分子標的スクリーニング成績「化学療法基盤情報支援班」報告-制がん候補物質のスクリーニング成績・第13報-2010
- Author(s)
  矢守隆夫、上原至雅、吉田稔、井本正哉、清宮啓之、水上民夫、川田学、長田裕之、松浦正明、深澤秀輔
- Total Pages
  158
- Publisher
  癌と化学療法
- Data Source
  KAKENHI-PROJECT-17012025
[Book] 癌と化学療法(特集・制がん剤の分子標的スクリーニング成績「化学療法基盤情報支援班」報告-制がん候補物質のスクリーニング成績・第13報-, 37)2010
- Author(s)
  矢守隆夫, 上原至雅, 吉田稔, 井本正哉, 清宮啓之, 水上民夫, 川田学, 長田裕之, 松浦正明, 深澤秀輔
- Data Source
  KAKENHI-PROJECT-17012025
[Book] 「化学療法基盤情報支援班」報告-制がん候補物質のスクリーニング成績・第13報2010
- Author(s)
  矢守隆夫、上原至誠、吉田稔、井本正哉、清宮啓之、水上民夫, 他
- Total Pages
  158
- Publisher
  癌と化学療法社
- Data Source
  KAKENHI-PROJECT-221S0001
[Book] Telomeres and Telomerase in Cancer(Keiko Hiyama 編, telomere binding proteins, and inhibitors.)2009
- Author(s)
  Seimiya H, Tsuruo T. Tankyrase 1
- Total Pages
  380
- Publisher
  Humana Press
- Data Source
  KAKENHI-PROJECT-17012025
[Book] "Telomeresand telomerase in cancer" Tankyrase 1, telomere binding proteins, and inhibitors2009
- Author(s)
  Seimiya H, Tsuruo T.
- Publisher
  Humana Press
- Data Source
  KAKENHI-PROJECT-17012025
[Book] Telomeres and Telomerase in Cancer(Tankyrase 1, telomere-binding proteins, and inhibitors)(edited by Hiyama K)2009
- Author(s)
  Seimiya H, Tsuruo T
- Publisher
  Humana Press
- Data Source
  KAKENHI-PROJECT-19370078
[Book] Telomeres and Telomerase in Cancer, Edited by Hiyama K, 「Tankyrase 1, telomere-binding proteins, and inhibitors」2009
- Author(s)
  Seimiya H
- Publisher
  Humana Press
- Data Source
  KAKENHI-PROJECT-20015047
[Book] Tankyrases. In "Encyclopedia of cancer 2nd ed."(Schwab M Ed.)2009
- Author(s)
  Seimiya H
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-20015047
[Book] Tanlyrase l,telo,ere-binding proteins, and inhibitors.(Hiyama, K., editor., Telomeres and Telomerase in Cancer.)2009
- Author(s)
  Seimiya, H., Tsuruo T.
- Publisher
  Humana Press
- Data Source
  KAKENHI-PROJECT-20015047
[Book] Tankyrases.(Schwab, M., editor., Encyclopedia of Cancer.2nd ed.)2009
- Author(s)
  Seimiya, H.
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-20015047
[Book] Tankyrase 1, telomere-binding proteins, and inhibitors. In "Telomeres and telomerase in cancer"(Hiyama K Ed.)2009
- Author(s)
  Seimiya H
- Publisher
  Humana Press
- Data Source
  KAKENHI-PROJECT-20015047
[Book] 生命の科学(テロメア長の制御機構, 59)2008
- Author(s)
  清宮啓之
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-20015047
[Book] 癌と化学療法(特集・制がん剤の分子標的スクリーニング成績「化学療法基盤情報支援班」報告-制がん候補物質のスクリーニング成績・第12報-, 34)2007
- Author(s)
  矢守隆夫, 上原至雅, 吉田稔, 井本正哉, 清宮啓之, 水上民夫, 川田学, 長田裕之, 松浦正明
- Data Source
  KAKENHI-PROJECT-17012025
[Book] 特集・制がん剤の分子標的スクリーニング成績「化学療法基盤情報支援班」報告-制がん候補物質のスクリーニング成績・第12報-.2007
- Author(s)
  矢守隆夫, 上原至雅, 吉田稔, 井本正哉, 清宮啓之, 水上民夫, 川田学, 長田裕之, 松浦正明.
- Publisher
  癌と化学療法
- Data Source
  KAKENHI-PROJECT-17012025
[Book] 文部科学省科学研究費補助金によるがん研究に係る特定領域研究 II「化学療法基盤情報支援班」報告2007
- Author(s)
  矢守隆夫, 上原至雅, 吉田稔, 井本正哉, 清宮啓之, 水上民夫, 川田学, 長田裕之, 松浦正明
- Publisher
  癌と化学療法(印刷中)
- Data Source
  KAKENHI-PROJECT-17012025
[Book] がんにおける脂質代謝、実験医学増刊号「がんと代謝」
- Author(s)
  右田敏郎、馬島哲夫、清宮啓之
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-22650230
[Journal Article] Phase II trial of biweekly cetuximab and irinotecan as third-line therapy for pretreated KRAS exon 2 wild-type colorectal cancer.2019
- Author(s)
  Suenaga Mitsukuni、Wakatsuki Takeru、Mashima Tetsuo、Ogura Mariko、Ichimura Takashi、Shinozaki Eiji、Nakayama Izuma、Osumi Hiroki、Ota Yumiko、Takahari Daisuke、Chin Keisho、Seimiya Hiroyuki、Yamaguchi Kensei
- Journal Title
  
  Cancer Sci
  
  Volume: 印刷中 Pages: 2567-2575
- DOI
  10.1007/s10637-019-00749-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07280, KAKENHI-PROJECT-18K07337, KAKENHI-PROJECT-16H04716
[Journal Article] Revisiting telomere shortening in cancer2019
- Author(s)
  Keiji Okamoto and Hiroyuki Seimiya
- Journal Title
  
  Cells
  
  Volume: 8 Pages: 107-107
- DOI
  10.3390/cells8020107
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07252, KAKENHI-PROJECT-18K19487, KAKENHI-PUBLICLY-18H04633, KAKENHI-PROJECT-16H04716
[Journal Article] Cell-based chemical fingerprinting identifies telomeres and lamin A as modifiers of DNA damage response in cancer cells2018
- Author(s)
  Fujiwara C, Muramatsu Y, Nishii M, Tokunaka K, Tahara H, Ueno M, Yamori T, Sugimoto Y, Seimiya H.
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Pages: 14827-14827
- DOI
  10.1038/s41598-018-33139-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07502, KAKENHI-PROJECT-18K07302, KAKENHI-PROJECT-18K19487, KAKENHI-PUBLICLY-18H04633, KAKENHI-PROJECT-16H04716, KAKENHI-PROJECT-16H06276
[Journal Article] RK-287107, a potent and specific tankyrase inhibitor, blocks colorectal cancer cell growth in a preclinical model.2018
- Author(s)
  Mizutani A, Yashiroda Y, Muramatsu Y, Yoshida H, Chikada T, Tsumura T, Okue M, Shirai F, Fukami T, Yoshida M, Seimiya H.
- Journal Title
  
  Cancer Science
  
  Volume: 109 Issue: 12 Pages: 4003-4014
- DOI
  10.1111/cas.13805
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07186, KAKENHI-PLANNED-18H05503, KAKENHI-PUBLICLY-18H04633, KAKENHI-PROJECT-16H04716, KAKENHI-PROJECT-16H06276
[Journal Article] Calpain-10 regulates actin dynamics by proteolysis of microtubule-associated protein 1B2018
- Author(s)
  Hatta Tomohisa、Iemura Shun-ichiro、Ohishi Tomokazu、Nakayama Hiroshi、Seimiya Hiroyuki、Yasuda Takao、Iizuka Katsumi、Fukuda Mitsunori、Takeda Jun、Natsume Tohru、Horikawa Yukio
- Journal Title
  
  Sci. Rep.
  
  Volume: 8 Pages: 16756-16756
- DOI
  10.1038/s41598-018-35204-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K00850, KAKENHI-PROJECT-18H02779, KAKENHI-PROJECT-17K19902, KAKENHI-PUBLICLY-18H04633
[Journal Article] Development of G-quadruplex ligand for selective induction of parallel-type topology2018
- Author(s)
  Yue Ma, Yamato Tsushima, Mai Sakuma, Shogo Sasaki, Keisuke Iida, Sachiko Okabe, Hiroyuki Seimiya, Takatsugu Hirokawa, Kazuo Nagasawa
- Journal Title
  
  Org. Biomol. Chem.
  
  Volume: 16 Pages: 7375-7382
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06276
[Journal Article] Development of G-quadruplex ligands for selective induction of a parallel-type topology2018
- Author(s)
  Ma Yue、Tsushima Yamato、Sakuma Mai、Sasaki Shogo、Iida Keisuke、Okabe Sachiko、Seimiya Hiroyuki、Hirokawa Takatsugu、Nagasawa Kazuo
- Journal Title
  
  Org. Biomol. Chem.
  
  Volume: 16 Pages: 7375-7382
- DOI
  10.1039/c8ob01702f
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05349, KAKENHI-PROJECT-16J08216, KAKENHI-PROJECT-16K13094, KAKENHI-PROJECT-18K19487, KAKENHI-PUBLICLY-18H04633
[Journal Article] MERIT40-dependent recruitment of tankyrase to damaged DNA and its implication for cell sensitivity to DNA-damaging anticancer drugs2018
- Author(s)
  Keiji Okamoto, Tomokazu Ohishi, Mika Kuroiwa, Shun-ichiro Iemura, Tohru Natsume and Hiroyuki Seimiya
- Journal Title
  
  Oncotarget
  
  Volume: 9 Pages: 35844-35855
- DOI
  10.18632/oncotarget.26312
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07252, KAKENHI-PUBLICLY-18H04633, KAKENHI-PROJECT-16H04716
[Journal Article] APC mutations as a potential biomarker for sensitivity to tankyrase inhibitors in colorectal cancer.2017
- Author(s)
  Noritaka Tanaka, Tetsuo Mashima, Anna Mizutani, Ayana Sato, Aki Aoyama, Bo Gong, Haruka Yoshida, Yukiko Muramatsu, Kento Nakata, Masaaki Matsuura, Ryohei Katayama, Satoshi Nagayama, Naoya Fujita, Yoshikazu Sugimoto, Hiroyuki Seimiya
- Journal Title
  
  Mol Cancer Ther
  
  Volume: 16 Pages: 739-751
- DOI
  10.1158/1535-7163.mct-16-0578
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H02368, KAKENHI-PROJECT-16H04715, KAKENHI-PROJECT-16H04716, KAKENHI-PROJECT-26430177, KAKENHI-PROJECT-15K14409, KAKENHI-PROJECT-15K14412
[Journal Article] Targeting glioma stem cells in vivo by a G-quadruplex-stabilizing synthetic macrocylic hexaoxazole2017
- Author(s)
  Nakamura T, Okabe S, Yoshida H, Iida K, Ma Y, Sasaki S, Yamori T, Shin-Ya K, Nakano I, Nagasawa K, Seimiya H.
- Journal Title
  
  Sci Rep
  
  Volume: 7 Pages: 3605-3605
- DOI
  10.1038/s41598-017-03785-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K13094, KAKENHI-PROJECT-26282214, KAKENHI-PROJECT-16J08216, KAKENHI-PROJECT-16K18908, KAKENHI-PROJECT-16H06276
[Journal Article] Senescence from glioma stem cell differentiation promotes tumor growth2016
- Author(s)
  Rie Ouchi, Sachiko Okabe, Toshiro Migita, Ichiro Nakano, Hiroyuki Seimiya
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 470 Pages: 275-281
- DOI
  10.1016/j.bbrc.2016.01.071
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-14J08396, KAKENHI-PROJECT-25290060
[Journal Article] Design, synthesis and evaluation of an L-Dopa-derived macrocyclic hexaoxazole (6OTD) as a G-quadruplex-selective ligand2016
- Author(s)
  Takahiro Nakamura, Yue Ma, Keisuke Iida, Terumi Ohtake, Hiroyuki Seimiya, and Kazuo Nagasawa
- Journal Title
  
  Heterocycles
  
  Volume: 92 Pages: 305-315
- DOI
  10.3987/com-15-13383
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-23105013, KAKENHI-PROJECT-13J07907, KAKENHI-PROJECT-26560444, KAKENHI-PROJECT-26860077, KAKENHI-PROJECT-25290060, KAKENHI-PROJECT-26282214
[Journal Article] Predicting risk at the end of the end: Telomere G-tail as a biomarker2016
- Author(s)
  Seimiya H
- Journal Title
  
  EBioMedicine
  
  Volume: 2 Pages: 802-803
- DOI
  10.1016/j.ebiom.2015.07.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26640109, KAKENHI-PROJECT-25290060
[Journal Article] Report on the use of non-clinical studies in the regulatory evaluation of oncology drugs.2016
- Author(s)
  Hayakawa Y, Kawada M, Nishikawa H, Ochiya T, Saya H, Seimiya H, Yao Y, Hayashi M, Kai C, Matsuda A, Naoe T, Ohtsu A, Okazaki T, Saji H, Sata M, Sugimura H, Sugiyama Y, Toi M, Irimura T
- Journal Title
  
  Cancer Sci.
  
  Volume: 107(2) Pages: 189-202
- DOI
  10.1111/cas.12857
- NAID
  120006333896
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670023, KAKENHI-PROJECT-25290060, KAKENHI-PROJECT-25293011, KAKENHI-PROJECT-25293184, KAKENHI-PROJECT-24229002, KAKENHI-PROJECT-15K06888, KAKENHI-PROJECT-16K15551, KAKENHI-PROJECT-26290054
[Journal Article] G-quadruplex ligand-induced DNA damage response coupled with telomere dysfunction and replication stress in glioma stem cells2016
- Author(s)
  Hasegawa D, Okabe S, Okamoto K, Nakano I, Shin-Ya K, Seimiya H
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 471 Pages: 75-81
- DOI
  10.1016/j.bbrc.2016.01.176
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25290060
[Journal Article] Design and synthesis of a berberine dimer: A fluorescent ligand with high affinity towards G-quadruplexes2015
- Author(s)
  M. Tera, T. Hirokawa, S. Okabe, K. Sugahara, H. Seimiya, K. Shimamoto
- Journal Title
  
  Chemistry
  
  Volume: 21 Pages: 14519-14528
- DOI
  10.1002/chem.201501693
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26750366, KAKENHI-PROJECT-25290060
[Journal Article] Comprehensive transcriptomic analysis of molecularly targeted drugs in cancer for target pathway evaluation.2015
- Author(s)
  Mashima T, Ushijima M, Matsuura M, Tsukahara S, Kunimasa K, Furuno A, Saito S, Kitamura M, Soma-Nagae T, Seimiya H, Dan S, Yamori T, Tomida A
- Journal Title
  
  Cancer Sci
  
  Volume: in press Pages: 909-20
- DOI
  10.1111/cas.12682
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25430120, KAKENHI-PROJECT-26430177, KAKENHI-PROJECT-26640109, KAKENHI-PROJECT-25290060, KAKENHI-PROJECT-25290061
[Journal Article] Telomeric repeat-containing RNA/G-quadruplex-forming sequences cause genome-wide alteration of gene expression in human cancer cells in vivo2015
- Author(s)
  Hirashima K, Seimiya H
- Journal Title
  
  Nucleic Acids Res
  
  Volume: 43 Pages: 2022-2032
- DOI
  10.1093/nar/gkv063
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25290060
[Journal Article] TRF1 ensures the centromeric function of Aurora-B and proper chromosome segregation.2014
- Author(s)
  Ohishi, T., Muramatsu, Y., Yoshida, H., Seimiya, H.
- Journal Title
  
  Molecular and Cellular Biology
  
  Volume: (in press) Pages: 2464-2478
- DOI
  10.1128/mcb.00161-14
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24650639, KAKENHI-PROJECT-25290060, KAKENHI-PROJECT-25871074, KAKENHI-PROJECT-26640109
[Journal Article] TRIBl supports prostate tumorigenesis and tumor-propagating cell survival by regulation of endoplasmic reticulum chaperone expression2014
- Author(s)
  Mashima T, Soma-Nagae T, Migita T, Kinoshita R, Iwamoto A, Yuasa T, Yonese J, Ishikawa Y, Seimiya H
- Journal Title
  
  Cancer Research
  
  Volume: 74 Pages: 4888-4897
- DOI
  10.1158/0008-5472.can-13-3718
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25290060, KAKENHI-PROJECT-26430177, KAKENHI-PROJECT-221S0001
[Journal Article] Reprogramming suppresses premature senescence phenotypes of Werner syndromecells and maintains chromosomal stability over long-term culture2014
- Author(s)
  Shimamoto A, Kagawa H, Zensho K, Sera Y, Kazuki Y, Osaki M, Oshimura M, Ishigaki Y, Hmasaki K, Kodama Y, Yuasa S, Fukuda K, Hirashima K, Seimiya H, Koyama H, Shimizu T, Takemoto M, Yokote K, Goto M, Tahara H.
- Journal Title
  
  PLoS One.;
  
  Volume: 9 Pages: 1-13
- DOI
  10.1371/journal.pone.0112900
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590902, KAKENHI-PUBLICLY-25112711, KAKENHI-PROJECT-25670030, KAKENHI-PLANNED-26115009, KAKENHI-PROJECT-26290047, KAKENHI-PROJECT-26310106, KAKENHI-PROJECT-26640091, KAKENHI-PROJECT-26670408, KAKENHI-PROJECT-221S0001
[Journal Article] TRF1 ensures the centromeric function of Aurora-B and proper chromosome segregation.2014
- Author(s)
  Ohishi T, Muramatsu Y, Yoshida H, Seimiya H
- Journal Title
  
  Mol Cell Biol
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24650639
[Journal Article] Inhibition of ATP citrate lyase induces triglyceride accumulation with altered fatty acid composition in cancer cells2014
- Author(s)
  5.Migita T, Okabe S, Ikeda K, Igarashi S, Sugawara S, Tomida A, Soga T, Taguchi R, Seimiya H.
- Journal Title
  
  Int J Cancer
  
  Volume: 135 Pages: 37-47
- DOI
  10.1002/ijc.28652
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24619007, KAKENHI-PROJECT-24650626, KAKENHI-PROJECT-24650639, KAKENHI-PROJECT-25290060, KAKENHI-PROJECT-25290061, KAKENHI-PROJECT-221S0001
[Journal Article] TRF1 ensures the centromeric function of Aurora-B and proper chromosome segregation.2014
- Author(s)
  Ohishi T, Muramatsu Y, Yoshida H, Seimiya H
- Journal Title
  
  Mol Cell Biol
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25290060
[Journal Article] Development of a gene expression database and related analysis programs for evaluation of anticancer compounds2013
- Author(s)
  Ushijima M, Mashima T, Tomida A, Dan S, Saito S, Furuno A, Tsukahara S, Seimiya H, Yamori T, Matsuura M
- Journal Title
  
  Cancer Sci
  
  Volume: 104 Pages: 360-368
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501319
[Journal Article] Telomere length influences cancer cell differentiation in vivo.2013
- Author(s)
  Hirashima, K., Migita, T., Sato, S., Muramatsu, Y., Ishikawa, Y., Seimiya, H.
- Journal Title
  
  Molecular and Cellular Biology
  
  Volume: 33 Pages: 2988-2995
- DOI
  10.1128/mcb.00136-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24650639, KAKENHI-PROJECT-25290060, KAKENHI-PROJECT-25640071
[Journal Article] Inhibition of ATP Citrate Lyase Induces an Anticancer Effect via Reactive Oxygen Species: AMPK as a Predictive Biomarker for Therapeutic Impact.2013
- Author(s)
  Migita, T., Okabe, S., Ikeda, K., Igarashi, S., Sugawara, S., Tomida, A., Taguchi, R., Soga, T., Seimiya, H.
- Journal Title
  
  Am J Pathol
  
  Volume: 182 Pages: 1800-1810
- DOI
  10.1016/j.ajpath.2013.01.048
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22134007, KAKENHI-PROJECT-22300341, KAKENHI-PROJECT-24619007, KAKENHI-PROJECT-24650626, KAKENHI-PROJECT-24650639, KAKENHI-PROJECT-25290060, KAKENHI-PROJECT-25290061, KAKENHI-PROJECT-221S0001, KAKENHI-PUBLICLY-23117527
[Journal Article] Development of a gene expression database and related analysis programs for evaluation of anticancer compounds2013
- Author(s)
  Ushijima, M., Mashima, T., Tomida, A., Dan, S., Saito, S., Furuno, A., Tsukahara, S., Seimiya, H., Yamori, T., Matsuura, M
- Journal Title
  
  Cancer Sci
  
  Volume: 104 Pages: 360-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300341
[Journal Article] Inhibition of ATP citrate lyase induces an anticancer effect via reactive oxygen species: AMPK as a predictive biomarker for therapeutic impact2013
- Author(s)
  Migita, T., Okabe, S., Ikeda, K., Igarashi, S., Sugawara, S., Tomida, A., Taguchi, R., Soga, T., Seimiya, H
- Journal Title
  
  Am J Pathol
  
  Volume: 182 Pages: 1800-1810
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300341
[Journal Article] Evaluation of the interaction between long telomeric DNA and macrocyclic hexaoxazole (6OTD) dimer of a G-quadruplex ligand2013
- Author(s)
  Iida, K.
- Journal Title
  
  Molecules
  
  Volume: 18 Pages: 4328-4341
- DOI
  10.3390/molecules18044328
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300341, KAKENHI-PROJECT-23310158, KAKENHI-PROJECT-24650639, KAKENHI-PROJECT-24651258, KAKENHI-PROJECT-25290060, KAKENHI-PLANNED-23105013, KAKENHI-PUBLICLY-23117527
[Journal Article] Interaction of long telomeric DNAs with macrocyclic hexaoxazole as a G-quadruplex ligand2013
- Author(s)
  Keisuke Iida, Gen Tsubouchi, Takahiro Nakamura, Satoki Majima, Hiroyuki Seimiya, and Kazuo Nagasawa
- Journal Title
  
  Med Chem Commun
  
  Volume: 4 Pages: 260-264
- DOI
  10.1039/c2md20234d
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310158, KAKENHI-PROJECT-24650639, KAKENHI-PROJECT-24651258, KAKENHI-PLANNED-23105013
[Journal Article] Development of a gene expression database and related analysis programs for evaluation of anticancer compounds2013
- Author(s)
  Ushijima M, Mashima T, Tomida A, Dan S, Saito S, Furuno A, Tsukahara S, Seimiya H, Yamori T, Matsuura M.
- Journal Title
  
  Cancer Science
  
  Volume: 104(3) Pages: 360-360
- DOI
  10.1111/cas.12071
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240092, KAKENHI-PROJECT-22300341, KAKENHI-PROJECT-23501319, KAKENHI-PROJECT-23701067, KAKENHI-PROJECT-24240042, KAKENHI-PROJECT-24650626, KAKENHI-PROJECT-24650639, KAKENHI-PROJECT-25290060, KAKENHI-PROJECT-25290061, KAKENHI-PROJECT-221S0001, KAKENHI-PUBLICLY-23117527
[Journal Article] Evaluation of the interaction between long telomeric DNA and macrocyclic hexaoxazole (6OTD) dimer of a G-quadruplex ligand2013
- Author(s)
  Iida, K., Majima, S., Nakamura, T., Seimiya, H., Nagasawa, K
- Journal Title
  
  Molecules
  
  Volume: 18 Pages: 4328-4341
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300341
[Journal Article] Telomestatin impairs glioma stem cell survival and growth through the disruption of telomeric G-quadruplex and inhibition of the proto-oncogene, c-Myb2012
- Author(s)
  Miyazaki T, Pan Y, Joshi K, Purohit D, Hu B, Demir H, Mazumder S, Okabe S, Yamori T, Viapiano M, Shin-Ya K, Seimiya H, Nakano I
- Journal Title
  
  Clin Cancer Res.
  
  Volume: 18(5) Pages: 1268-1280
- DOI
  10.1158/1078-0432.ccr-11-1795
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240092, KAKENHI-PROJECT-22300341, KAKENHI-PROJECT-24650639, KAKENHI-PUBLICLY-23117527
[Journal Article] A caged ligand for a telomeric G-quadruplex2012
- Author(s)
  Nakamura, T., Iida, K., Tera, M., Shin-ya, K., Seimiya, H., Nagasawa, K
- Journal Title
  
  Chembiochem
  
  Volume: 13 Pages: 774-777
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300341
[Journal Article] Telomestatin impairs glioma stem cell survival and growth through the disruption of telomeric G-quadruplex and inhibition of the proto-oncogene, c-Myb2012
- Author(s)
  Miyazaki, T., Pan, Y., Joshi, K., Purohit, D., Hu, B., Demir, H., Mazumder, S., Okabe, S., Yamori, T.,Viapiano, M., Shin-ya, K., Seimiya, H., Nakano, I
- Journal Title
  
  Clin Cancer Res
  
  Volume: 18 Pages: 1268-1280
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300341
[Journal Article] Tankyrase-1 function at telomeres and during mitosis is regulated by Polo-like kinase-1-mediated phosphorylation2012
- Author(s)
  Ha, G. H., Kim, H. S., Go, H., Lee, H., Seimiya, H., Chung, D. H., Lee, C. W
- Journal Title
  
  Cell Death Differ
  
  Volume: 19 Pages: 321-332
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300341
[Journal Article] et al., HDAC8 mutations in Cornelia de Lange syndrome affect the cohesin acetylation cycle2012
- Author(s)
  Deardorff, M.A., Seimiya, H.
- Journal Title
  
  Nature
  
  Volume: 489 Pages: 313-317
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300341
[Journal Article] A caged ligand for a telomeric G-quadruplex2012
- Author(s)
  T.Nakamura, K.Iida, M.Tera, K.Shin-ya, H.Seimiya, K.Nagasawa
- Journal Title
  
  Chembiochem
  
  Volume: Vol.13 Pages: 774-777
- DOI
  10.1002/cbic.201200013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J07978, KAKENHI-PROJECT-22300341, KAKENHI-PROJECT-23310158, KAKENHI-PROJECT-24650639, KAKENHI-PROJECT-24651258, KAKENHI-PLANNED-23105013, KAKENHI-PUBLICLY-23117527
[Journal Article] JBIR-120: a new growth inhibitor of hormone-refractory prostate cancer cells2012
- Author(s)
  Kawahara, T., Hosoya, T., Tsukamoto, M., Okabe, S., Yamamura, H., Hayakawa, M., Seimiya, H., Takagi, M., Shin-Ya, K
- Journal Title
  
  J Antibiot
  
  Volume: 65 Pages: 373-375
- NAID
  10030955529
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300341
[Journal Article] HDAC8 mutations in Cornelia de Lange Syndrome affect the cohesin acetylation cycle2012
- Author(s)
  Deardorff MA
- Journal Title
  
  Nature
  
  Volume: 489(7415) Pages: 313-317
- DOI
  10.1038/nature11316
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21681025, KAKENHI-PROJECT-22221009, KAKENHI-PROJECT-22300341, KAKENHI-PROJECT-23651243, KAKENHI-PROJECT-23710213, KAKENHI-PROJECT-24370076, KAKENHI-PROJECT-24650639, KAKENHI-PLANNED-22125008, KAKENHI-PLANNED-23114003, KAKENHI-PUBLICLY-23117527, KAKENHI-PUBLICLY-24114517
[Journal Article] Molecular pharmacological approach reveals potential new strategies to suppress androgen receptor signaling in prostate cancer2011
- Author(s)
  Mashima, T., Okabe, S., Seimiya, H
- Journal Title
  
  Mol Cell Pharmacol
  
  Volume: 3 Pages: 7-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300341
[Journal Article] Role of acyl-CoA synthetases in glioma cell survival and its therapeutic implication2011
- Author(s)
  Mashima, T., Seimiya, H.
- Journal Title
  
  Tumors of the Central Nervous System
  
  Volume: 1 Pages: 337-340
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650230
[Journal Article] Fission yeast pot1 and recQ helicase are required for efficient chromosome segregation2011
- Author(s)
  Takahashi, K., Imano, R., Kibe, T., Seimiya, H., Muramatsu, Y., Kawabata, N., Tanaka, G., Matsumoto, Y., Hiromoto, T., Koizumi, Y., Nakazawa, N., Yanagida, M., Yukawa, M., Tsuchiya, E., Ueno, M
- Journal Title
  
  Mol Cell Biol
  
  Volume: 31 Pages: 95-506
- NAID
  120004205356
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300341
[Journal Article] Role of acyl-CoA synthetases in glioma cell survival and its therapeutic implication2011
- Author(s)
  Mashima, T., Seimiya, H
- Journal Title
  
  Tumors of the Central Nervous System
  
  Volume: 1 Pages: 337-340
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300341
[Journal Article] Role of acyl-CoA synthetases in glioma cell survival and its therapeutic implication2011
- Author(s)
  Mashima T, Seimiya H
- Journal Title
  
  Tumors of the Central Nervous System
  
  Volume: 1 Pages: 337-340
- Data Source
  KAKENHI-PROJECT-23501319
[Journal Article] Molecular pharmacological approach reveals potential new strategies to suppress androgen receptor signaling in prostate cancer2011
- Author(s)
  Mashima, T., Okabe, S., Seimiya, H.
- Journal Title
  
  Mol Cell Pharmacol
  
  Volume: 3 Pages: 7-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650230
[Journal Article] Molecular pharmacological approach reveals potential new strategies to suppress androgen receptor signaling in prostate cancer2011
- Author(s)
  Mashima T, Okabe S, Seimiya H
- Journal Title
  
  Mol Cell Pharmacol
  
  Volume: 3 Pages: 7-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501319
[Journal Article] Pharmacological targeting of constitutively active truncated androgen receptor by nigericin and suppression of hormone-refractory prostate cancer cell growth2010
- Author(s)
  Mashima, T., Okabe, S., Seimiya, H.
- Journal Title
  
  Mol Pharmacol
  
  Volume: 78 Pages: 846-854
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650230
[Journal Article] A novel yeast cell-based screen identifies flavone as a tankyrase inhibitor.2010
- Author(s)
  Yashiroda, Y., Okamoto, R., Hatsugai, K., Takemoto, Y., Goshima, N., Saito, T., Hamamoto, M., Sugimoto, Y., Osada, H., Seimiya, H., Yoshida, M.
- Journal Title
  
  Biochem Biophys Res Comma 394
  
  Pages: 569-573
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015047
[Journal Article] Role of insulin-like growth factor binding protein 2 in lung adenocarcinoma : IGF-independent antiapoptotic effect via caspase-32010
- Author(s)
  Migita, T., Narita, T., Asaka, R., Miyagi, E., Nagano, H., Nomura, K., Matsuura, M., Satoh, Y., Okumura, S., Nakagawa, K., Seimiya, H., Ishikawa, Y.
- Journal Title
  
  Am J Pathol
  
  Volume: 176 Pages: 1756-1766
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650230
[Journal Article] TRF1 mediates mitotic abnormalities induced by Aurora-Aoverexpression.2010
- Author(s)
  Ohishi, T., Hirota, T., Tsuruo, T., Seimiya, H.
- Journal Title
  
  Cancer Res 70
  
  Pages: 2041-2052
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015047
[Journal Article] Role of insulin-like growth factor binding protein 2 in lung adenocarcinoma: IGF-independent antiapoptotic effect via caspase-3.2010
- Author(s)
  Migita, T., Narita, T., Asaka, R., Miyagi, E., Nagano, H., Nomura, K., Matsuura, M., Satoh, Y., Okumura, S., Nakagawa, K., Seimiya, H., Ishikawa, Y.
- Journal Title
  
  Am J Pathol 176
  
  Pages: 1756-1766
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015047
[Journal Article] Pharmacological targeting of constitutively active truncated androgen receptor by nigericin and suppression of hormone-refractory prostate cancer cell growth2010
- Author(s)
  Mashima, T., Okabe, S., Seimiya, H
- Journal Title
  
  Mol Pharmacol
  
  Volume: 78 Pages: 846-854
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300341
[Journal Article] Generation of induced pluripotent stem cells from human terminally differentiated circulating T cells2010
- Author(s)
  Seki, T., Yuasa, S., Oda, M., Egashira, T., Yae, K., Kusumoto, D., Nakata, H., Tohyama, S., Hashimoto, H., Kodaira, M., Okada, Y., Seimiya, H., Fusaki, N., Hasegawa, M., Fukuda, K
- Journal Title
  
  Cell Stem Cell
  
  Volume: 7 Pages: 11-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300341
[Journal Article] Role of insulin-like growth factor binding protein 2 in lung adenocarcinoma: IGF-independent antiapoptotic effect via caspase-32010
- Author(s)
  Migita, T., Narita, T., Asaka, R., Miyagi, E., Nagano, H., Nomura, K., Matsuura, M., Satoh, Y., Okumura, S., Nakagawa, K., Seimiya, H., Ishikawa, Y
- Journal Title
  
  Am J Pathol
  
  Volume: 176 Pages: 1756-1766
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300341
[Journal Article] TRF1 mediates mitotic abnormalities induced by Aurora-A overexpression2010
- Author(s)
  Ohishi, T., Hirota, T., Tsuruo, T., Seimiya, H
- Journal Title
  
  Cancer Res
  
  Volume: 70 Pages: 2041-2052
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300341
[Journal Article] Visualization of G-quadruplexes by using a BODIPY-labeled macrocyclic heptaoxazole.2010
- Author(s)
  Tera, M., Iida, K., Ikebukuro, K., Seimiya, H., Shin-Ya, K., Nagasawa, K.
- Journal Title
  
  Org Biomol Chem 8
  
  Pages: 2749-2755
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015047
[Journal Article] A novel yeast cell-based screen identifies flavone as a tankyrase inhibitor2010
- Author(s)
  Yashiroda, Y., Okamoto, R., Hatsugai, K., Takemoto, Y., Goshima, N., Saito, T., Hamamoto, M., Sugimoto, Y., Osada, H., Seimiya, H., Yoshida, M
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 394 Pages: 569-573
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300341
[Journal Article] TRF1 mediates mitotic abnormalities induced by Aurora-A overexpression2010
- Author(s)
  Ohishi, T., Hirota, T., Tsuruo, T., Seimiya, H.
- Journal Title
  
  Cancer Res
  
  Volume: 70 Pages: 2041-2052
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650230
[Journal Article] Tankyrase-1 assembly to large protein complexes blocks its telomeric function2010
- Author(s)
  Hatsugai, K., Ohishi, T., Sugimoto, Y., Seimiya, H
- Journal Title
  
  FEBS Lett
  
  Volume: 584 Pages: 3885-3890
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300341
[Journal Article] Visualization of G-quadruplexes by using a BODIPY-labeled macrocyclic heptaoxazole2010
- Author(s)
  Tera, M., Iida, K., Ikebukuro, K., Seimiya, H., Shin-Ya, K., Nagasawa, K
- Journal Title
  
  Org Biomol Chem
  
  Volume: 8 Pages: 2749-2755
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300341
[Journal Article] TRF1 mediates mitotic abnormalities induced by Aurora-A overexpression2010
- Author(s)
  Ohishi T, Hirota T, Tsuruo T, Seimiya H.
- Journal Title
  
  Cancer Res 70(5)
  
  Pages: 2041-52
- Data Source
  KAKENHI-PROJECT-17012025
[Journal Article] TRF1 mediates mitotic abnormalities induced by Aurora-A overexpression2010
- Author(s)
  Ohishi T, Hirota T, Tsuruo T, Seimiya H.
- Journal Title
  
  Cancer Res 70
  
  Pages: 2041-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012025
[Journal Article] Expression of mutant RPA in human cancer cells causes telomere shortening2010
- Author(s)
  Kobayashi, Y., Sato, K., Kibe, T., Seimiya, H., Nakamura, A., Yukawa, M., Tsuchiya, E., Ueno, M
- Journal Title
  
  Biosci Biotechnol Biochem
  
  Volume: 74 Pages: 382-385
- NAID
  10027551727
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300341
[Journal Article] Expression of mutant RPA in human cancer cells causes telomere shortening.2010
- Author(s)
  Kobayashi, Y., Sato, K., Kibe, T., Seimiya, H., Nakamura, A., Yukawa, M., Tsuchiya, E., Ueno, M.
- Journal Title
  
  Biosci Biotechnol Biochem 74
  
  Pages: 382-385
- NAID
  10027551727
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015047
[Journal Article] Telomeres and Telomerase in Cancer, Edited by Hiyama K. 「Tankyrase 1, telomere-binding proteins, and inhibitors」2009
- Author(s)
  Seimiya H
- Journal Title
  
  Humana Press
  
  Pages: 281-292
- Data Source
  KAKENHI-PROJECT-19370078
[Journal Article] De novo fatty-acid synthesis and related pathways as molecular targets for cancer therapy.2009
- Author(s)
  Mashima, T., Seimiya, H., Tsuruo, T.
- Journal Title
  
  Br J Cancer 100
  
  Pages: 1369-1372
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015047
[Journal Article] Targeting Tankyrase 1 as a therapeutic strategy for BRCA-associated cancer.2009
- Author(s)
  McCabe, N., Cerone, M.A., Ohishi, T., Seimiya, H., Lord, C.J., Ashworth, A.
- Journal Title
  
  Oncogene 28
  
  Pages: 1465-1470
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015047
[Journal Article] Promotion of glioma cell survival by acyl-CoA synthetase 5 under extracellular acidosis conditions.2009
- Author(s)
  Mashima, T., Sato, S., Sugimoto, Y., Tsuruo, T., Seimiya, H.
- Journal Title
  
  Oncogene 28
  
  Pages: 9-19
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015047
[Journal Article] Promotion of glioma cell survival by acyl-CoA synthetase 5 under extracellular acidosis conditions2009
- Author(s)
  Mashima T, Sato S, Sugimoto Y, Tsuruo T, Seimiya H
- Journal Title
  
  Oncogene 28
  
  Pages: 9-19
- Data Source
  KAKENHI-PROJECT-19370078
[Journal Article] Targeting Tankyrase 1 as a therapeutic strategy for BRCA-associated cancer2009
- Author(s)
  McCabe N, Cerone MA, Ohishi T, Seimiya H, Lord CJ, Ashworth A
- Journal Title
  
  Oncogene 28
  
  Pages: 1465-1470
- Data Source
  KAKENHI-PROJECT-19370078
[Journal Article] Telomeres and Telomerase in Cancer, Edited by Hiyama K. 「Tankyrase 1, telomere-binding proteins, and inhibitors」2009
- Author(s)
  Seimiya H
- Journal Title
  
  Humana Press
  
  Pages: 281-292
- Data Source
  KAKENHI-PROJECT-20659024
[Journal Article] De novo fatty-acid synthesis and related pathways as molecular targets for cancer therapy2009
- Author(s)
  Mashima T, Seimiya H, Tsuruo T
- Journal Title
  
  Br J Caner 100
  
  Pages: 1369-1372
- Data Source
  KAKENHI-PROJECT-19370078
[Journal Article] Acyl-CoA synthetase as a cancer survival factor: its inhibition enhances the efficacy of etoposide.2009
- Author(s)
  Mashima, T., Sato, S., Okabe, S., Miyata, S., Matsuura, M., Sugimoto, Y., Tsuruo, T., Seimiya, H.
- Journal Title
  
  Cancer Sci 100
  
  Pages: 1556-1562
- NAID
  10027193846
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015047
[Journal Article] ATP citrate lyase: activation and therapeutic implications in non-small cell lung cancer.2008
- Author(s)
  Migita, T., Narita, T., Nomura, K., Miyagi, E., Inazuka, F., Matsuura, M., Ushijima, M., Mashima, T., Seimiya, H., Satoh, Y., Okumura, S., Nakagawa, K., Ishikawa, Y.
- Journal Title
  
  Cancer Res 68
  
  Pages: 8547-8554
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015047
[Journal Article] Promotion of glioma cell survival by acyl-CoA synthetase 5 under extracellular acidosis conditions.2008
- Author(s)
  Mashima, T. Sato, S. Sugimoto, Y. Tsuruo, T. Seimiya, H.
- Journal Title
  
  Oncogene 28
  
  Pages: 9-19
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012025
[Journal Article] ATP citrate lyase : activation and therapeutic implications in non-small cell lung cancer2008
- Author(s)
  Migita T, Narita T, Nomura K, Miyagi E, Inazuka F, Matsuura M, Ushijima M, Mashima T, Seimiya H, Satoh Y, Okumura S, Nakagawa K, Ishikawa Y
- Journal Title
  
  Cancer Res 68
  
  Pages: 8547-8554
- Data Source
  KAKENHI-PROJECT-19370078
[Journal Article] Telomere elongation by a mutant tankyrase 1 without TRF1 poly(ADP-ribosyl)ation.2008
- Author(s)
  Muramatsu, Y., Tahara, H., Ono, T., Tsuruo, T., Seimiya, H.
- Journal Title
  
  Exp Cell Res 314
  
  Pages: 1115-1124
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015047
[Journal Article] Telomere elongation by a mutant tankyrase 1 without TRF1 poly(ADP-ribosyl)ation.2008
- Author(s)
  Muramatsu, Y. Tahara, H. Ono, T. Tsuruo, T. Seimiya, H.
- Journal Title
  
  Exp Cell Res 314
  
  Pages: 1115-24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012025
[Journal Article] Telomere elongation by a mutant tankyrase 1 without TRF1 poly(ADP-ribosyl)ation2008
- Author(s)
  Muramatsu Y, Tahara H, Ono T, Tsuruo T, Seimiya H
- Journal Title
  
  Exp Cell Res 314
  
  Pages: 1115-1124
- Data Source
  KAKENHI-PROJECT-19370078
[Journal Article] ATP citrate lyase: activation and therapeutic implications in non-small cell lung cancer.2008
- Author(s)
  Migita, T. Narita, T. Nomura, K. Miyagi, E. Inazuka, F. Matsuura, M. Ushijima, M. Mashima, T. Seimiya, H. Satoh, Y. Okumura, S. Nakagawa, K. Ishikawa, Y.
- Journal Title
  
  Cancer Res 68
  
  Pages: 8547-54
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012025
[Journal Article] Cross-species difference in telomeric function of tankyrase 1.2007
- Author(s)
  Muramatsu, Y. Ohishi, T. Sakamoto, M. Tsuruo. T. Seimiya. H.
- Journal Title
  
  Cancer Sci 98
  
  Pages: 850-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012025
[Journal Article] Evaluation of tankyrase inhibition in whole cells2007
- Author(s)
  Ohishi T, Tsuruo T, Seimiya H
- Journal Title
  
  Meth Mol Biol 405
  
  Pages: 133-146
- Data Source
  KAKENHI-PROJECT-19370078
[Journal Article] Cross-species difference in telomeric function of tankyrase 12007
- Author(s)
  Muramatsu Y, Ohishi T, Sakamoto M, Tsuruo T, Seimiya H
- Journal Title
  
  Cancer Sci 98
  
  Pages: 850-857
- Data Source
  KAKENHI-PROJECT-19370078
[Journal Article] hnRNP A3 binds to and protects mammalian telomeric repeats in vitro2007
- Author(s)
  Tanaka E, Fukuda H, Nakashima K, Tsuchiya N, Seimiya H, Nakagama H
- Journal Title
  
  Biochem Biophys Res Commun 358
  
  Pages: 608-614
- Data Source
  KAKENHI-PROJECT-19370078
[Journal Article] Cross-species difference in telomeric function of tankyrase 1.2007
- Author(s)
  Muramatsu, Y., Ohishi, T., Sakamoto, M., Tsuruo, T., Seimiya, H.
- Journal Title
  
  Cancer Sci. (in press)
- Data Source
  KAKENHI-PROJECT-17012025
[Journal Article] The telomeric PARP, tankyrases, as targets for cancer therapy.2006
- Author(s)
  Seimiya, H.
- Journal Title
  
  Br. J. Cancer 94
  
  Pages: 341-345
- Data Source
  KAKENHI-PROJECT-18015047
[Journal Article] The telomeric PARP, tankyrases, as targets for cancer therapy2006
- Author(s)
  Seimiya, H.
- Journal Title
  
  Br.J.Cancer 94
  
  Pages: 341-345
- Data Source
  KAKENHI-PROJECT-17770151
[Journal Article] The telomeric PARP, tankyrases, as targets for cancer therapy2006
- Author(s)
  Seimiya, H.
- Journal Title
  
  Br.J.Cancer 94
  
  Pages: 341-345
- Data Source
  KAKENHI-PROJECT-17016078
[Journal Article] The telomeric PARP, tankyrases, as targets for cancer therapy.2006
- Author(s)
  Seimiya, H.
- Journal Title
  
  Br J Cancer. 94
  
  Pages: 341-345
- Data Source
  KAKENHI-PROJECT-17012025
[Journal Article] The telomeric PARP, tankyrases, as targets for cancer therapy.2006
- Author(s)
  Seimiya, H.
- Journal Title
  
  Br. J. Cancer 94
  
  Pages: 341-345
- Data Source
  KAKENHI-PROJECT-17770151
[Journal Article] Tankyrase 1 as a target for telomere-directed molecular cancer therapeutics2005
- Author(s)
  Seimiya, H.
- Journal Title
  
  Cancer Cell 7
  
  Pages: 25-37
- Data Source
  KAKENHI-PROJECT-17016078
[Journal Article] Tankyrase 1 as a target for telomere-directed molecular cancer therapeutics.2005
- Author(s)
  Seimiya, H.
- Journal Title
  
  Cancer Cell 7
  
  Pages: 25-37
- Data Source
  KAKENHI-PROJECT-16023268
[Journal Article] Tankyrase 1 as a target for telomere-directed molecular cancer therapeutics.2005
- Author(s)
  Seimiya, H.
- Journal Title
  
  Cancer Call 7
  
  Pages: 25-37
- Data Source
  KAKENHI-PROJECT-15770114
[Journal Article] Tankyrase 1 as a target for telomere-directed molecular cancer therapeutics2005
- Author(s)
  Seimiya, H.
- Journal Title
  
  Cancer Cell 7
  
  Pages: 25-37
- Data Source
  KAKENHI-PROJECT-17770151
[Journal Article] Tankyrase 1 as a target for telomere-directed molecular cancer therapeutics.2005
- Author(s)
  Seimiya H, Muramatsu Y, Ohishi T, Tsuruo T.
- Journal Title
  
  Cancer Cell 7(1)
  
  Pages: 25-37
- Data Source
  KAKENHI-PROJECT-17012025
[Journal Article] Functional subdomain in the ankyrin domain of tankyrase 1 required for poly(ADP-ribosyl)ation of TRF1 and telomere elogation.2004
- Author(s)
  Seimiya, H.
- Journal Title
  
  Mol.Cell.Biol. 24
  
  Pages: 1944-1955
- Data Source
  KAKENHI-PROJECT-16023268
[Journal Article] Functional subdomain in the ankyrin domain of tankyrase 1 required for poly(ADP-ribosyl)ation of TRF1 and telomere elongation.2004
- Author(s)
  Seimiya, H.
- Journal Title
  
  Mol.Cell.Biol. 24
  
  Pages: 1944-1955
- Data Source
  KAKENHI-PROJECT-15770114
[Journal Article] Acyl-CoA synthetase as a cancer survival factor : its inhibition enhances the efficacy of etoposide
- Author(s)
  Mashima T, Sato S, Okabe S, Miyata S, Matsuura M, Sugimoto Y, Tsuruo T, Seimiya H
- Journal Title
  
  Cancer Sci (in press)
- NAID
  10027193846
- Data Source
  KAKENHI-PROJECT-19370078
[Journal Article] Telomere length influences cancer cell differentiation in vivo
- Author(s)
  Hirashima,K., Migita,T., Sato, S., Muramatsu, Y., Ishikawa,Y., Seimiya, H
- Journal Title
  
  Mol Cell Biol, in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300341
[Patent] タンキラーゼ阻害剤感受性を検査する方法、及びその効果を増強する医薬組成物2019
- Inventor(s)
  清宮啓之、藤原千明、杉本芳一
- Industrial Property Rights Holder
  公益財団法人がん研究会
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-16H04716
[Patent] 抗膵がん剤2018
- Inventor(s)
  長澤和夫、松田未沙子、馬悦、清宮啓之
- Industrial Property Rights Holder
  東京農工大学、がん研究会
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-18K19487
[Patent] タンキラーゼ阻害剤感受性を検査する方法、及びその効果を増強する医薬組成物2018
- Inventor(s)
  清宮啓之、藤原千明、杉本芳一
- Industrial Property Rights Holder
  公益財団法人がん研究会
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-16H04716
[Patent] 抗膵がん剤2018
- Inventor(s)
  長澤和夫、松田未沙子、馬悦、清宮啓之
- Industrial Property Rights Holder
  東京農工大学、がん研究会
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Data Source
  KAKENHI-PUBLICLY-18H04633
[Patent] 抗膵がん剤2018
- Inventor(s)
  長澤和夫、松田未沙子、馬悦、清宮啓之
- Industrial Property Rights Holder
  国立大学法人東京農工大学、公益財団法人がん研究会
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-136579
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-16H06276
[Patent] マルチキナーゼ阻害剤の有効性と安全性を予測する検査方法、検査キット、及びバイオマーカー2015
- Inventor(s)
  末永光邦、水沼信之、馬島哲夫、清宮啓之
- Industrial Property Rights Holder
  公益財団法人がん研究会
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2015-251386
- Filing Date
  2015-12-24
- Data Source
  KAKENHI-PROJECT-221S0001
[Patent] 神経膠腫幹細胞を標的とするグアニン四重鎖リガンド2014
- Inventor(s)
  長澤和夫、清宮啓之、飯田圭介、中村貴大
- Industrial Property Rights Holder
  東京農工大学、（公財）がん研究会
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-229221
- Filing Date
  2014-11-11
- Data Source
  KAKENHI-PROJECT-25290060
[Presentation] Telomere as the starting point of anticancer drug discovery2019
- Author(s)
  Hiroyuki Seimiya
- Organizer
  11th AACR-JCA Joint Conference on Breakthroughs in Cancer Research: Biology to Precision Medicine
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19487
[Presentation] グアニン４重鎖安定化物質の分子プロファイリングとがん創薬への展開2019
- Author(s)
  清宮啓之、新家一男、長澤和夫
- Organizer
  日本農芸化学会2019年度大会
- Invited
- Data Source
  KAKENHI-PROJECT-18K19487
[Presentation] グアニン４重鎖安定化物質の分子プロファイリングとがん創薬への展開2019
- Author(s)
  清宮啓之、新家一男、長澤和夫
- Organizer
  日本農芸化学会2019年度大会
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04633
[Presentation] Telomere as the starting point of anticancer drug discovery2019
- Author(s)
  Seimiya, H.
- Organizer
  OIST Seminar
- Invited
- Data Source
  KAKENHI-PROJECT-16H04716
[Presentation] Telomere as the starting point of anticancer drug discovery2019
- Author(s)
  Seimiya, H.
- Organizer
  11th AACR-JCA Joint Conference on Breakthroughs in Cancer Research: Biology to Precision Medicine
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04716
[Presentation] 生理活性天然物をリードとするグアニン四重鎖を標的とした抗がん剤の創製研究2019
- Author(s)
  馬悦, 中村貴大, 岡部幸子, 新家一男, 清宮啓之, 長澤和夫
- Organizer
  平成30年度先端モデル動物支援プラットフォーム成果発表会
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] Telomere as the starting point of anticancer drug discovery2019
- Author(s)
  Hiroyuki Seimiya
- Organizer
  11th AACR-JCA Joint Conference on Breakthroughs in Cancer Research: Biology to Precision Medicine
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04633
[Presentation] Telomere as the starting point of anticancer drug discovery2019
- Author(s)
  Seimiya, H.
- Organizer
  11th AACR-JCA Joint Conference on Breakthroughs in Cancer Research : Biology to Precision Medicine
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] Targeting colorectal cancer stem-like CD44-positive cells by tankyrase inhibitors2018
- Author(s)
  Tetsuo Mahima, Myung-kyu Jang, Hiroyuki Seimiya
- Organizer
  The 14th Japan-Korea Joint Symposium on Cancer and Ageing Research
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04716
[Presentation] ポリ(ADP-リボシル)化酵素タンキラーゼを標的としたがん創薬2018
- Author(s)
  清宮啓之
- Organizer
  理研シンポジウム第4回 DMP創薬ワークショップ
- Invited
- Data Source
  KAKENHI-PROJECT-16H04716
[Presentation] アニリン型側鎖を有する大環状ヘキサオキサゾール化合物の合成とグアニン四重鎖の安定可能2018
- Author(s)
  松田未沙子, 馬悦, 小林美月, 岡部幸子, 広川貴次, 清宮啓之, 長澤和夫
- Organizer
  第62回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] G-quadruplex as a molecular target for cancer therapy2018
- Author(s)
  Hiroyuki Seimiya
- Organizer
  第41回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04633
[Presentation] Targeting colorectal cancer stem cells by tankyrase inhibition2018
- Author(s)
  Tetsuo Mashima, Myung-Kyu Jang, Hiroyuki Seimiya
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16H04716
[Presentation] 大環状ヘキサオキサゾール誘導体を用いた生細胞内でのグアニン四重鎖構造の可視化2018
- Author(s)
  安田瑞穂, 馬悦, 岡部幸子, 清宮啓之, Young-Tae Chang, 長澤和夫
- Organizer
  第13回化学生態学研究会
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] G-quadruplex as a molecular target for cancer therapy2018
- Author(s)
  Seimiya, H.
- Organizer
  The 14th Japan-Korea Joint Symposium on Cancer and Ageing Research
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] G-quadruplex nucleic acids as a molecular target for cancer therapy2018
- Author(s)
  Hiroyuki Seimiya, Kazuo Shin-ya, Kazuo Nagasawa
- Organizer
  第77回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-18K19487
[Presentation] G-quadruplex nucleic acid as a molecular target for cancer therapy2018
- Author(s)
  Seimiya, H.
- Organizer
  The 77th Annual Meeting of Japanese Cancer Association (JCA), Symposium
- Invited
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] 大環状ヘキサオキサゾール誘導体を用いた生細胞内でのグアニン四重鎖構造の可視化2018
- Author(s)
  安田瑞穂, 馬悦, 岡部幸子, 清宮啓之, Young-Tae Chang, 長澤和夫
- Organizer
  日本ケミカルバイオロジー学会第13回年会
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] Telomere as the starting point of anticancer drug discovery2018
- Author(s)
  Seimiya, H.
- Organizer
  RIKEN IMS Cancer Immunology Seminar Series
- Invited
- Data Source
  KAKENHI-PROJECT-16H04716
[Presentation] タンキラーゼ阻害剤による大腸がん幹細胞の標的化とその作用メカニズム2018
- Author(s)
  張明奎、馬島哲夫、清宮啓之
- Organizer
  第22回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-16H04716
[Presentation] テロメアの長さによって発現変動する遺伝子群が腫瘍形態に及ぼす影響2018
- Author(s)
  藤原理恵、岡本啓治、吉田喜香、右田敏郎、清宮啓之
- Organizer
  先端モデル動物支援プラットフォーム平成29年度成果発表会
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] shRNAスクリーニングによるタンキラーゼ合成致死因子の同定2018
- Author(s)
  藤原千明、杉本芳一、清宮啓之
- Organizer
  平成30年度新学術領域研究・学術研究支援基盤形成・先端モデル動物支援プラットフォーム・若手支援技術講習会
- Data Source
  KAKENHI-PROJECT-16H04716
[Presentation] Identification of potential biomarkers for sensitivity to tankyrase inhibitors in patient-derived colorectal cancer2018
- Author(s)
  Oishi T, Mashima T, Sato A, Yoshida H, Aoyama A, Gong B, Katayama R, Nagayama S, Fujita N, and Seimiya H.
- Organizer
  The 14th Japan-Korea Joint Symposium on Cancer and Ageing Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04716
[Presentation] G-quadruplex nucleic acids as a molecular target for cancer therapy2018
- Author(s)
  Hiroyuki Seimiya, Kazuo Shin-ya, Kazuo Nagasawa
- Organizer
  第77回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04633
[Presentation] G-quadruplex as a molecular target for cancer therapy2018
- Author(s)
  Seimiya, H.
- Organizer
  The 41st Annual Meeting of the Molecular Biology Society of Japan
- Invited
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] テロメア関連因子を標的としたがん創薬2018
- Author(s)
  清宮啓之
- Organizer
  愛知県がんセンター研究セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-16H04716
[Presentation] タンキラーゼ阻害剤による大腸がん幹細胞の増殖抑制とその作用メカニズム2018
- Author(s)
  張明奎、馬島哲夫、吉田喜香、清宮啓之
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16H04716
[Presentation] G-quadruplex as a molecular target for cancer therapy2018
- Author(s)
  Hiroyuki Seimiya
- Organizer
  第41回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18K19487
[Presentation] 染色体の末端から始まるがん創薬2018
- Author(s)
  清宮啓之
- Organizer
  慶應義塾大学矢上キャンパス特別講義セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-16H04716
[Presentation] In situ Click反応を基盤とする生細胞中でのG4の可視化2018
- Author(s)
  安田瑞穂, 馬悦, 岡部幸子, 清宮啓之, Young-Tae Chang, 長澤和夫
- Organizer
  第36回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] 大腸がん幹細胞を標的とするタンキラーゼ阻害剤とその作用メカニズム2018
- Author(s)
  張明奎、馬島哲夫、清宮啓之
- Organizer
  平成30年度新学術領域研究・学術研究支援基盤形成・先端モデル動物支援プラットフォーム・若手支援技術講習会
- Data Source
  KAKENHI-PROJECT-16H04716
[Presentation] 新規タンキラーゼ阻害剤RK-287107は非臨床モデルで大腸がんを抑制する2018
- Author(s)
  水谷アンナ、村松由起子、吉田喜香、清宮啓之
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16H04716
[Presentation] Telomeres as the starting point of cancer biology and drug discovery2018
- Author(s)
  Seimiya, H.
- Organizer
  Nagoya University Cancer Science Course
- Invited
- Data Source
  KAKENHI-PROJECT-16H04716
[Presentation] Targeting glioma stem cells by pharmacological stabilization of G-quadruplexes2018
- Author(s)
  Sachiko Okabe, Takahiro Nakamura, Daiki Hasegawa, Reina Kojima, Keiji Okamoto, Ichiro Nakano, Kazuo Shin-ya, Kazuo Nagasawa, Hiroyuki Seimiya
- Organizer
  AACR Annual Meeting 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04633
[Presentation] テロメアから始まるがん創薬2018
- Author(s)
  清宮啓之
- Organizer
  お茶の水がん学アカデミア第145回集会
- Invited
- Data Source
  KAKENHI-PROJECT-16H04716
[Presentation] New mode-of-action of a telomerase inhibitor MST-312 and modifiers of its anticancer efficacy2018
- Author(s)
  藤原千明、村松由起子、矢守隆夫、杉本芳一、清宮啓之
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PUBLICLY-18H04633
[Presentation] 新規タンキラーゼ阻害剤RK-287107は非臨床モデルで大腸がんを抑制する2018
- Author(s)
  水谷アンナ、村松由起子、吉田喜香、清宮啓之
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] Targeting glioma stem cells by pharmacological stabilization of G-quadruplexes2018
- Author(s)
  Sachiko Okabe, Takahiro Nakamura, Daiki Hasegawa, Reina Kojima, Keiji Okamoto, Ichiro Nakano, Kazuo Shin-ya, Kazuo Nagasawa, Hiroyuki Seimiya
- Organizer
  AACR Annual Meeting 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19487
[Presentation] New mode-of-action of a telomerase inhibitor MST-312 and modifiers of its anticancer efficacy2018
- Author(s)
  藤原千明、村松由起子、矢守隆夫、杉本芳一、清宮啓之
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K19487
[Presentation] G-quadruplex in cancer biology and drug dcvelopment2017
- Author(s)
  清宮啓之
- Organizer
  Tokyo Modical University, Instituto of Medical Science, Ist International Symposium "Role of Aging and Cancer"
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] 分子プロファイリング支援活動のご紹介2017
- Author(s)
  清宮啓之
- Organizer
  先端モデル動物支援プラットフォーム平成29年度若手支援技術講習会
- Invited
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] テロメラーゼ阻害剤MST-312の即時的制がん効果を規定する因子2017
- Author(s)
  藤原千明、村松由起子、水谷アンナ、矢守隆夫、杉本芳一、清宮啓之
- Organizer
  先端モデル動物支援プラットフォーム平成29年度若手支援技術講習会
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] 大腸がん幹細胞を標的とする化合物の探索と細胞傷害性抗がん剤との併用効果2017
- Author(s)
  張明奎、馬島哲夫、清宮啓之
- Organizer
  先端モデル動物支援プラットフォーム平成29年度若手支援技術講習会
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] 鶴尾隆賞受賞講演 : テロメアを起点としたがんの本態解明と分子標的治療薬の開発2017
- Author(s)
  清宮啓之
- Organizer
  第21回日本がん分子標的治療学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] PARPファミリー酵素を標的とする抗がん剤の開発2016
- Author(s)
  清宮啓之
- Organizer
  理研創薬･医療技術基盤プログラム第３回ワークショップ
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2016-03-03
- Invited
- Data Source
  KAKENHI-PROJECT-26640109
[Presentation] TNKS1BP1 regulates the actin filament dynamics and cancer cell invasion2016
- Author(s)
  Yoshida H, Ohishi T, Muramatsu Y, Seimiya H
- Organizer
  10th AACR-JCA Joint Conference on Breakthroughs in Cancer Research: From Biology to Therapeutics
- Place of Presentation
  Hawaii, USA
- Year and Date
  2016-02-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26640109
[Presentation] Senescence from cancer stem cell differentiation promotes tumor growth in glioblastoma2016
- Author(s)
  Rie Ouchi, Sachiko Okabe, Toshiro Migita, Ichiro Nakano, Hiroyuki Seimiya
- Organizer
  The 10th AACR-JCA Joint Conference on Breakthroughs in Cancer Research: From Biology to Therapeutics
- Place of Presentation
  Hawaii, USA
- Year and Date
  2016-02-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25290060
[Presentation] Telomere maintenance system as an anticancer therapeutic target2016
- Author(s)
  清宮啓之
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-06
- Invited
- Data Source
  KAKENHI-PROJECT-16H04716
[Presentation] A preferential growth inhibitory activity of a G-quadruplex ligand against glioma stem cells2016
- Author(s)
  Takahiro Nakamura, Sachiko Okabe, Keisuke Iida, Takao Yamori, Kazuo Shin-ya, Ichiro Nakano, Kazuo Nagasawa and Hiroyuki Seimiya
- Organizer
  The 13th Korea-Japan Joint Symposium on Cancer and Ageing Research
- Place of Presentation
  Jeju, Korea
- Year and Date
  2016-02-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25290060
[Presentation] TERRA G-quadruplex as a potential modifier of cancer behavior2016
- Author(s)
  Hiroyuki Seimiya
- Organizer
  The 13th Korea-Japan Joint Symposium on Cancer and Ageing Research
- Place of Presentation
  Jeju, Korea
- Year and Date
  2016-02-25
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25290060
[Presentation] New mode-of-action of anticancer effects of G-quadruplex ligands2016
- Author(s)
  Reina Kojima, Keiji Okamoto, Sachiko Okabe, Takahiro Nakamura, Kazuo Nagasawa, and Hiroyuki Seimiya
- Organizer
  The 13th Korea-Japan Joint Symposium on Cancer and Ageing Research
- Place of Presentation
  Jeju, Korea
- Year and Date
  2016-02-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25290060
[Presentation] がん創薬にむけたテロメア研究の進歩2016
- Author(s)
  清宮啓之
- Organizer
  第14回日本臨床腫瘍学会学術集会
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2016-07-28
- Invited
- Data Source
  KAKENHI-PROJECT-16H04716
[Presentation] PARPファミリー酵素を標的とする抗がん剤の開発2016
- Author(s)
  清宮啓之
- Organizer
  CBI学会2016年大会
- Place of Presentation
  タワーホール船堀（東京都江戸川区）
- Year and Date
  2016-10-25
- Invited
- Data Source
  KAKENHI-PROJECT-16H04716
[Presentation] TERRA G-quadruplex as a potential modifier of the genome-wide gene expression and cancer behavior in vivo2015
- Author(s)
  Hiroyuki Seimiya
- Organizer
  5th International Meeting on Quadruplex Nucleic Acids
- Place of Presentation
  Bordeaux、France
- Year and Date
  2015-05-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25290060
[Presentation] Growth inhibition mechanisms for a telomestatin derivative against glioma stem cells2015
- Author(s)
  中村貴大、岡部幸子、飯田圭介、新家一男、長澤和夫、清宮啓之
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  愛知県名古屋市
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25290060
[Presentation] G-quadruplex, a potential modifier of cancer behavior and a target for the therapeutic intervention2015
- Author(s)
  清宮啓之
- Organizer
  国際高等研究所研究プロジェクト「クロマチン・デコーディング」2014年度第1回研究会
- Place of Presentation
  国際高等研究所（京都府・木津川市）
- Year and Date
  2015-03-19
- Invited
- Data Source
  KAKENHI-PROJECT-25290060
[Presentation] G-quadruplex: a potential modifier of cancer behavior and a therapeutic target for glioma stem cells2015
- Author(s)
  Hiroyuki Seimiya
- Organizer
  Developmental Therapeutics Branch, National Cancer Institute, Special DTB Seminar
- Place of Presentation
  Bethesda, USA
- Year and Date
  2015-04-23
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25290060
[Presentation] Glioma stem cell-selective antitumor effect of a novel G-quadruplex ligand2015
- Author(s)
  Takahiro Nakamura, Sachiko Okabe, Keisuke Iida, Takao Yamori, Kazuo Shin-ya, Ichiro Nakano, Kazuo Nagasawa and Hiroyuki Seimiya
- Organizer
  The 20th Japanese Foundation for Cancer Research-International Symposium on Cancer Chemotherapy
- Place of Presentation
  Daiba, Tokyo
- Year and Date
  2015-12-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25290060
[Presentation] Senescence derived from glioma stem cell differentiation and its implication in the tumor progression2015
- Author(s)
  Rie Ouchi, Sachiko Okabe, Toshiro Migita, Ichiro Nakano, Hiroyuki Seimiya
- Organizer
  BMB2015
- Place of Presentation
  兵庫県神戸市
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25290060
[Presentation] ポリADP-リボシル化酵素タンキラーゼの多元的機能と創薬応用2015
- Author(s)
  清宮啓之
- Organizer
  BMB2015（第38回日本分子生物学会年会、第88回日本生化学会大会合同大会）
- Place of Presentation
  兵庫県神戸市
- Year and Date
  2015-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-26640109
[Presentation] がん分子標的創薬をめぐる最近の話題2015
- Author(s)
  清宮啓之
- Organizer
  第74回日本癌学会学術総会モーニングレクチャー
- Place of Presentation
  愛知県名古屋市
- Year and Date
  2015-10-08
- Invited
- Data Source
  KAKENHI-PROJECT-25290060
[Presentation] グアニン４重鎖リガンドによる神経膠腫幹細胞のターゲティング2015
- Author(s)
  清宮啓之
- Organizer
  日本癌学会シンポジウム/共同利用･共同研究拠点シンポジウム「がん幹細胞･微小環境･分子標的～がん進展制御への挑戦」
- Place of Presentation
  石川県立音楽堂交流ホール（石川県・金沢市）
- Year and Date
  2015-01-22
- Invited
- Data Source
  KAKENHI-PROJECT-25290060
[Presentation] テロメスタチン誘導体による神経膠腫幹細胞の増殖抑制メカニズム2015
- Author(s)
  中村貴大、岡部幸子、飯田圭介、矢守隆夫、新家一男、長澤和夫、清宮啓之
- Organizer
  第19回日本がん分子標的治療学会学術集会
- Place of Presentation
  愛媛県松山市
- Year and Date
  2015-06-10
- Data Source
  KAKENHI-PROJECT-25290060
[Presentation] 神経膠腫幹細胞に対するグアニン四重鎖リガンドの制がん作用機序2015
- Author(s)
  長谷川大記、岡部幸子、中野伊知郎、新家一男、清宮啓之
- Organizer
  BMB2015
- Place of Presentation
  兵庫県神戸市
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25290060
[Presentation] G-quadruplex: a potential modifier of cancer behavior and a therapeutic target for glioma stem cells2015
- Author(s)
  清宮啓之
- Organizer
  慶應義塾大学理工学部セミナー
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2015-10-28
- Invited
- Data Source
  KAKENHI-PROJECT-25290060
[Presentation] タンキラーゼ結合蛋白質TAB182による細胞浸潤能の制御2015
- Author(s)
  大石智一、村松由起子、清宮啓之
- Organizer
  第19回日本がん分子標的治療学会学術集会
- Place of Presentation
  愛知県松山市
- Year and Date
  2015-06-10
- Data Source
  KAKENHI-PROJECT-26640109
[Presentation] タンキラーゼ結合タンパク質TAB182はアクチン細胞骨格の再構成を介してがん細胞の浸潤を調節する2015
- Author(s)
  大石智一、吉田喜香、村松由起子、清宮啓之
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  愛知県名古屋市
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26640109
[Presentation] グアニン４重鎖を標的としたがん創薬2015
- Author(s)
  清宮啓之
- Organizer
  愛媛大学医学部分子病態医学セミナー
- Place of Presentation
  愛媛県東温市
- Year and Date
  2015-04-03
- Invited
- Data Source
  KAKENHI-PROJECT-25290060
[Presentation] テロメア蛋白質TRF1による染色体分配制御2014
- Author(s)
  清宮啓之、大石智一
- Organizer
  第73回日本癌学会学術総会シンポジウム
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-09-26
- Invited
- Data Source
  KAKENHI-PROJECT-26640109
[Presentation] PARP阻害剤をめぐる最近の話題2014
- Author(s)
  清宮啓之
- Organizer
  第18回日本がん分子標的治療学会学術集会 Year in Review
- Place of Presentation
  仙台市情報・産業プラザ（宮城県・仙台市）
- Year and Date
  2014-06-27
- Invited
- Data Source
  KAKENHI-PROJECT-26640109
[Presentation] 神経膠腫幹細胞に対するテロメスタチン誘導体の選択的な抗腫瘍効果2014
- Author(s)
  中村貴大、岡部幸子、飯田圭介、矢守隆夫、新家一男、中野伊知郎、長澤和夫、清宮啓之
- Organizer
  文科省新学術領域研究・がん支援「化学療法基盤支援活動」第三回シンポジウムアカデミアからの抗がん剤創薬に向けて-天然物の有効利用
- Place of Presentation
  万国津梁館(沖縄県・名護市)
- Year and Date
  2014-05-12
- Data Source
  KAKENHI-PROJECT-221S0001
[Presentation] G-quadruplex as a therapeutic target for glioma stem cells2014
- Author(s)
  Seimiya H
- Organizer
  The 19th Japan-Korea Cancer Research Workshop
- Place of Presentation
  Jeju (Korea)
- Year and Date
  2014-11-29
- Invited
- Data Source
  KAKENHI-PROJECT-25290060
[Presentation] PARP阻害剤をめぐる最近の話題(Year in Review)2014
- Author(s)
  清宮啓之
- Organizer
  第18回日本がん分子標的治療学会学術集会
- Place of Presentation
  仙台市情報・産業プラザ(宮城県・仙台市)
- Year and Date
  2014-06-27
- Invited
- Data Source
  KAKENHI-PROJECT-221S0001
[Presentation] Telomeres and G-quadruplexes as targets for cancer therapy.2014
- Author(s)
  Seimiya, H.
- Organizer
  Kangwon National University Research Seminar
- Place of Presentation
  Gangwon-Do, Korea
- Invited
- Data Source
  KAKENHI-PROJECT-24650639
[Presentation] 再燃性前立腺がんにおける短鎖型アンドロゲン受容体の役割とその制御物質2014
- Author(s)
  岡部幸子、馬島哲夫、清宮啓之
- Organizer
  文科省新学術領域研究・がん支援「化学療法基盤支援活動」第三回シンポジウムアカデミアからの抗がん剤創薬に向けて-天然物の有効利用
- Place of Presentation
  万国津梁館(沖縄県・名護市)
- Year and Date
  2014-05-12
- Data Source
  KAKENHI-PROJECT-221S0001
[Presentation] Telomeres and G-quadruplexes as targets for cancer therapy2014
- Author(s)
  Seimiya, H.
- Organizer
  Kangwon National University Research Seminar
- Place of Presentation
  Gangwon-Do, Korea
- Invited
- Data Source
  KAKENHI-PROJECT-25290060
[Presentation] G-quadruplex, a potential modifier of cancer behavior and a therapeutic target for glioma stem cells2014
- Author(s)
  Seimiya H
- Organizer
  The 4th Japan-France Cancer Workshop
- Place of Presentation
  関西セミナーハウス（京都府・京都市）
- Year and Date
  2014-11-19
- Invited
- Data Source
  KAKENHI-PROJECT-25290060
[Presentation] Targeted therapy of glioma stem cells with G-quadruplex ligands.2013
- Author(s)
  Seimiya, H
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PROJECT-24650639
[Presentation] RNAiスクリーニングおよび遺伝子発現データを用いた統合的解析による前立腺がん幹細胞生存因子の同定2013
- Author(s)
  馬島哲夫、湯浅健、清宮啓之
- Organizer
  第17回日本がん分子標的治療学会学術集会
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-23501319
[Presentation] 抗がん剤探索アプローチの変遷と最近の話題2013
- Author(s)
  清宮啓之
- Organizer
  日本癌学会学術総会（モーニングレクチャー）
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-221S0001
[Presentation] TRF1 ensures proper chromosome segregation in mitosis.2013
- Author(s)
  Seimiya, H
- Organizer
  Cold Spring Harbor Laboratory Meeting on Telomeres & Telomerase
- Place of Presentation
  Cold Spring Harbor, NY, USA
- Data Source
  KAKENHI-PROJECT-25290060
[Presentation] 抗がん剤探索アプローチの変遷と最近の話題2013
- Author(s)
  清宮啓之
- Organizer
  第72回日本癌学会学術総会モーニングレクチャー
- Place of Presentation
  横浜
- Year and Date
  2013-10-05
- Invited
- Data Source
  KAKENHI-PROJECT-24650639
[Presentation] Targeted therapy of glioma stem cells with G-quadruplex ligands2013
- Author(s)
  Seimiya, H
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PROJECT-25290060
[Presentation] 遺伝子発現解析とRNAi探索による前立腺がん腫瘍源細胞生存因子の同定2013
- Author(s)
  馬島哲夫、清宮啓之
- Organizer
  第７２回日本癌学会学術集会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23501319
[Presentation] Targeting glioma stem cells by G-quadruplex ligands2013
- Author(s)
  Seimiya, H
- Organizer
  第9回日米合同癌会議
- Place of Presentation
  (Ninth AACR-JCA Joint Conference, Breakthroughs in Basic and Translational Cancer Research) (Hawaii, USA)
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] Targeting glioma stem cells by G-quadruplex ligands2013
- Author(s)
  Seimiya, H.
- Organizer
  9th AACR-JCA Joint Conference: Breakthroughs in Basic and Translational Cancer Research
- Place of Presentation
  Hawaii, USA
- Data Source
  KAKENHI-PROJECT-24650639
[Presentation] Targeting glioma stem cells by G-quadruplex ligands2013
- Author(s)
  Seimiya, H.
- Organizer
  9th AACR-JCA Joint Conference: Breakthroughs in Basic and Translational Cancer Research
- Place of Presentation
  Hawaii, USA
- Year and Date
  2013-02-21
- Data Source
  KAKENHI-PUBLICLY-23117527
[Presentation] Targeting glioma stem cells by G-quadruplex ligands2013
- Author(s)
  Seimiya, H.
- Organizer
  9th AACR-JCA Joint Conference: Breakthroughs in Basic and Translational Cancer Research
- Place of Presentation
  Hawaii, USA
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] TRF1 regulates the microtubule-kinetochore attachment and contributes to proper chromosome segregation2013
- Author(s)
  Seimiya, H.
- Organizer
  1st International Symposium on Protein Modifications in Pathogenic Dysregulation of Signaling
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24650639
[Presentation] TRF1 regulates the microtubule-kinetochore attachment and contributes to proper chromosome segregation2013
- Author(s)
  Seimiya, H
- Organizer
  1st International Symposium on Protein Modifications in Pathogenic Dysregulation of Signaling
- Place of Presentation
  (東京)
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] テロメア配列はヒトがん細胞の遺伝子発現を制御する2013
- Author(s)
  平島匡太郎、清宮啓之
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2013-12-03
- Data Source
  KAKENHI-PROJECT-24650639
[Presentation] TRF1 ensures proper chromosome segregation in mitosis.2013
- Author(s)
  Seimiya, H
- Organizer
  Cold Spring Harbor Laboratory Meeting on Telomeres & Telomerase
- Place of Presentation
  Cold Spring Harbor, NY, USA
- Data Source
  KAKENHI-PROJECT-24650639
[Presentation] 抗がん剤探索アプローチの変遷と最近の話題2013
- Author(s)
  清宮啓之
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PROJECT-25290060
[Presentation] TRF1 regulates the microtubule-kinetochore attachment and contributes to proper chromosome segregation2013
- Author(s)
  Seimiya, H.
- Organizer
  1st International Symposium on Protein Modifications in Pathogenic Dysregulation of Signaling
- Place of Presentation
  東京
- Year and Date
  2013-02-01
- Data Source
  KAKENHI-PUBLICLY-23117527
[Presentation] TRF1 regulates the microtubule-kinetochore attachment and contributes to proper chromosome segregation2013
- Author(s)
  Seimiya, H.
- Organizer
  1st International Symposium on Protein Modifications in Pathogenic Dysregulation of Signaling
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] グアニン４重鎖リガンドによる神経膠腫幹細胞のターゲティング2013
- Author(s)
  清宮啓之
- Organizer
  第17回日本がん分子標的治療学会学術集会
- Place of Presentation
  京都
- Invited
- Data Source
  KAKENHI-PROJECT-24650639
[Presentation] TRF1 ensures proper chromosome segregation in mitosis2013
- Author(s)
  Seimiya, H., Ohishi, T., Muramatsu, Y.
- Organizer
  Cold Spring Harbor Laboratory Meeting on Telomeres & Telomerase
- Place of Presentation
  Cold Spring Harbor, NY, USA
- Year and Date
  2013-05-02
- Data Source
  KAKENHI-PROJECT-24650639
[Presentation] G4リガンドによるがん幹細胞のターゲティング2013
- Author(s)
  清宮啓之
- Organizer
  第47回愛媛大学分子病態医学セミナー
- Place of Presentation
  松山
- Invited
- Data Source
  KAKENHI-PROJECT-24650639
[Presentation] グアニン４重鎖リガンドによる神経膠腫幹細胞のターゲティング2013
- Author(s)
  清宮啓之
- Organizer
  第17回日本がん分子標的治療学会学術集会
- Place of Presentation
  京都
- Invited
- Data Source
  KAKENHI-PROJECT-25290060
[Presentation] Telomere length influences cancer cell differentiation in vivo2013
- Author(s)
  Seimiya, H
- Organizer
  3rd GDRI French Japanese Cancer Meeting
- Place of Presentation
  Toulouse, France
- Invited
- Data Source
  KAKENHI-PROJECT-25290060
[Presentation] 抗がん剤探索アプローチの変遷と最近の話題2013
- Author(s)
  清宮啓之
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PROJECT-24650639
[Presentation] Telomere length influences cancer cell differentiation in vivo2013
- Author(s)
  Seimiya H.
- Organizer
  The 3rd GDRI French Japanese Cancer Meeting
- Place of Presentation
  Toulouse, France
- Year and Date
  2013-11-20
- Invited
- Data Source
  KAKENHI-PROJECT-24650639
[Presentation] Telomere length influences cancer cell differentiation in vivo.2013
- Author(s)
  Seimiya, H
- Organizer
  3rd GDRI French Japanese Cancer Meeting
- Place of Presentation
  Toulouse, France
- Invited
- Data Source
  KAKENHI-PROJECT-24650639
[Presentation] G4リガンドによるがん幹細胞のターゲティング2013
- Author(s)
  清宮啓之
- Organizer
  第47回愛媛大学分子病態医学セミナー
- Place of Presentation
  松山
- Invited
- Data Source
  KAKENHI-PROJECT-25290060
[Presentation] Targeting glioma stem cells by G-quadruplex ligands2012
- Author(s)
  Seimiya, H.
- Organizer
  The 2nd Japanese-French Cancer Workshop
- Place of Presentation
  徳島
- Invited
- Data Source
  KAKENHI-PROJECT-24650639
[Presentation] TRF1 regulates the microtubule-kinetochore attachment and contributes to proper chromosome segregation2012
- Author(s)
  Seimiya, H
- Organizer
  EMBO Conference on Telomeres and the DNA Damage Response
- Place of Presentation
  (L'Isle sur la Sorgue, France)
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] がん研究基礎セミナー「新薬の原石をもとめて〜抗がん剤・化合物スクリーニング〜」2012
- Author(s)
  清宮啓之
- Organizer
  平成24年度がん若手研究者ワークショップ
- Place of Presentation
  蓼科
- Invited
- Data Source
  KAKENHI-PROJECT-24650639
[Presentation] Targeting glioma stem cells by G-quadruplex ligands2012
- Author(s)
  Seimiya, H
- Organizer
  2nd Japanese-French Cancer Workshop(招待講演)
- Place of Presentation
  (鳴門)
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] 新薬の原石をもとめて　～抗がん剤・化合物スクリーニング～2012
- Author(s)
  Seimiya, H.
- Organizer
  平成24年度がん若手研究者ワークショップ
- Place of Presentation
  蓼科
- Invited
- Data Source
  KAKENHI-PROJECT-24650639
[Presentation] TRF1 regulates the microtubule-kinetochore attachment and contributes to proper chromosome segregation2012
- Author(s)
  Seimiya, H.
- Organizer
  EMBO Conference on Telomeres and the DNA Damage Response
- Place of Presentation
  L’Isle sur la Sorgue, France
- Data Source
  KAKENHI-PROJECT-24650639
[Presentation] Regulation of chromosome segregation by a telomeric protein2012
- Author(s)
  Seimiya, H.
- Organizer
  The 11th Korea-Japan-Germany Joint Symposium on Cancer and Ageing Research
- Place of Presentation
  Gyeongju, Korea
- Year and Date
  2012-07-05
- Invited
- Data Source
  KAKENHI-PUBLICLY-23117527
[Presentation] Regulation of chromosome segregation by a telomeric protein2012
- Author(s)
  Seimiya, H
- Organizer
  The 11th Korea-Japan-Germany Joint Symposium on Cancer and Ageing Research(招待講演)
- Place of Presentation
  (Gyeongju, Korea)
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] Targeting glioma stem cells by G-quadruplex ligands2012
- Author(s)
  Seimiya, H.
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Invited
- Data Source
  KAKENHI-PROJECT-24650639
[Presentation] Targeting glioma stem cells by G-quadruplex ligands2012
- Author(s)
  Seimiya, H.
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Invited
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] ポリ(ADP-リボシル)化酵素タンキラーゼによる細胞制御と阻害剤開発2012
- Author(s)
  清宮啓之
- Organizer
  慶應義塾大学先端医科学研究所セミナー(招待講演)
- Place of Presentation
  (東京)
- Year and Date
  2012-10-11
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] Regulation of chromosome segregation by a telomeric protein2012
- Author(s)
  Seimiya, H.
- Organizer
  The 11th Korea-Japan-Germany Joint Symposium on Cancer and Ageing Research
- Place of Presentation
  Gyeongju, Korea
- Invited
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] 新薬の原石をもとめて　～抗がん剤・化合物スクリーニング～2012
- Author(s)
  Seimiya, H.
- Organizer
  平成24年度がん若手研究者ワークショップ
- Place of Presentation
  蓼科
- Invited
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] がん研究基礎セミナー「新薬の原石をもとめて　～抗がん剤・化合物スクリーニング～」2012
- Author(s)
  清宮啓之
- Organizer
  2012年度文部科学省科学研究費補助金新学術領域研究「がん研究分野の特性等を踏まえた支援活動」がん若手研究者ワークショップ
- Place of Presentation
  蓼科
- Year and Date
  2012-09-08
- Data Source
  KAKENHI-PROJECT-221S0001
[Presentation] TRF1 regulates the microtubule-kinetochore attachment and contributes to proper chromosome segregation2012
- Author(s)
  Seimiya, H.
- Organizer
  EMBO Conference on Telomeres and the DNA Damage Response
- Place of Presentation
  L’Isle sur la Sorgue, France
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] Regulation of chromosome segregation by a telomeric protein2012
- Author(s)
  Seimiya, H.
- Organizer
  The 2nd Japanese-French Cancer Workshop
- Place of Presentation
  徳島
- Invited
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] テロメア長が腫瘍内遺伝子発現に及ぼす影響2012
- Author(s)
  平島匡太郎、右田敏郎、佐藤重男、石川雄一、清宮啓之
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24650639
[Presentation] Targeting glioma stem cells by G-quadruplex ligands2012
- Author(s)
  Seimiya, H
- Organizer
  第71回日本癌学会学術総会International Session(招待講演)
- Place of Presentation
  (札幌)
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] Targeting glioma stem cells by G-quadruplex ligands2012
- Author(s)
  Seimiya, H.
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Year and Date
  2012-09-19
- Invited
- Data Source
  KAKENHI-PUBLICLY-23117527
[Presentation] Regulation of chromosome segregation by a telomeric protein2012
- Author(s)
  Seimiya, H.
- Organizer
  The 2nd Japanese-French Cancer Workshop
- Place of Presentation
  徳島
- Year and Date
  2012-11-28
- Invited
- Data Source
  KAKENHI-PUBLICLY-23117527
[Presentation] TRF1 regulates the microtubule-kinetochore attachment and contributes to proper chromosome segregation2012
- Author(s)
  Seimiya, H.
- Organizer
  EMBO Conference on Telomeres and the DNA Damage Response
- Place of Presentation
  L’Isle sur la Sorgue, France
- Year and Date
  2012-10-02
- Data Source
  KAKENHI-PUBLICLY-23117527
[Presentation] 新薬の原石をもとめて　～抗がん剤・化合物スクリーニング～2012
- Author(s)
  Seimiya, H.
- Organizer
  平成24年度がん若手研究者ワークショップ
- Place of Presentation
  蓼科
- Year and Date
  2012-09-05
- Invited
- Data Source
  KAKENHI-PUBLICLY-23117527
[Presentation] Regulation of chromosome segregation by a telomeric protein2012
- Author(s)
  Seimiya, H.
- Organizer
  The 11th Korea-Japan-Germany Joint Symposium on Cancer and Ageing Research
- Place of Presentation
  Gyeongju, Korea
- Invited
- Data Source
  KAKENHI-PROJECT-24650639
[Presentation] TRF1 regulates the microtubule-kinetochore attachment and contributes to proper chromosome segregation2012
- Author(s)
  Seimiya, H., Ohishi, T., Muramatsu Y.
- Organizer
  EMBO Conference on Telomeres and the DNA Damage Response
- Place of Presentation
  L'Isle sur la Sorgue, France
- Data Source
  KAKENHI-PROJECT-24650639
[Presentation] Inhibition of ATP citrate lyase mediates anticancer effects via reactive oxygen species and triglyceride accumulation2011
- Author(s)
  右田敏郎、岡部幸子、池田和貴、曽我朋義、田口良、清宮啓之
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22650230
[Presentation] がん治療応用を目指したテロメア研究の現況2011
- Author(s)
  清宮啓之
- Organizer
  医薬ライセンシング協会第236回月例会(招待講演)
- Place of Presentation
  (東京)
- Year and Date
  2011-11-15
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] がんとは何でしょう?2011
- Author(s)
  清宮啓之
- Organizer
  新学術領域研究「がん研究分野の特性等を踏まえた支援活動」青少年・市民公開講座～いま知っておきたい「がん」のこと～
- Place of Presentation
  福島県立医科大学(福島県)(招待講演)
- Year and Date
  2011-09-17
- Data Source
  KAKENHI-PUBLICLY-23117527
[Presentation] がん治療応用を目指したテロメア研究の現況2011
- Author(s)
  清宮啓之
- Organizer
  医薬ライセンシング協会第236回月例会
- Place of Presentation
  学士会館(東京都)(招待講演)
- Year and Date
  2011-11-15
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] テロメアを起点とした創薬シーズ開発と新たながん生物学研究への展開2011
- Author(s)
  清宮啓之
- Organizer
  愛媛大学第4回分子病態医学セミナー
- Place of Presentation
  愛媛大学(愛媛県)(招待講演)
- Year and Date
  2011-09-07
- Data Source
  KAKENHI-PUBLICLY-23117527
[Presentation] Telomere fingerprinting for drug sensitivity studies and cancer cell biology2011
- Author(s)
  Seimiya, H
- Organizer
  ニース大学招待セミナー(招待講演)
- Place of Presentation
  (フランス・ニース)
- Year and Date
  2011-11-21
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] Telomere fingerprinting for drug sensitivity studies and cancer cell biology2011
- Author(s)
  清宮啓之
- Organizer
  ニース大学招待セミナー
- Place of Presentation
  ニース大学(フランス・ニース)(招待講演)
- Year and Date
  2011-11-21
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] 脂質代謝酵素を標的とした乳癌、前立腺癌の治療とその分子機構2011
- Author(s)
  右田敏郎、岡部幸子、清宮啓之
- Organizer
  第11回関東ホルモンと癌研究会
- Place of Presentation
  東京
- Year and Date
  2011-01-29
- Data Source
  KAKENHI-PROJECT-22650230
[Presentation] テロメアを起点とした創薬シーズ開発と新たながん生物学研究への展開2011
- Author(s)
  清宮啓之
- Organizer
  愛媛大学第4回分子病態医学セミナー
- Place of Presentation
  愛媛大学(愛媛県)(招待講演)
- Year and Date
  2011-09-07
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] ポリ(ADP-リボシル)化酵素タンキラーゼ1の新たな分子機能2011
- Author(s)
  清宮啓之
- Organizer
  第84回日本生化学会大会シンポジウム「ADP-リボシル化によるシグナル伝達制御」
- Place of Presentation
  国立京都国際会館(京都府)(招待講演)
- Year and Date
  2011-09-21
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] Regulation of chromosome segregation by a telomeric protein TRF12011
- Author(s)
  Seimiya, H
- Organizer
  日仏がん研究ワークショップ(招待講演)
- Place of Presentation
  (フランス・モンペリエ)
- Year and Date
  2011-11-22
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] がんとは何でしょう?2011
- Author(s)
  清宮啓之
- Organizer
  新学術領域研究「がん研究分野の特性等を踏まえた支援活動」青少年・市民公開講座～いま知っておきたい「がん」のこと～
- Place of Presentation
  福島県立医科大学(福島県)(招待講演)
- Year and Date
  2011-09-17
- Data Source
  KAKENHI-PROJECT-22650230
[Presentation] ポリ(ADP-リボシル)化酵素タンキラーゼ1の新たな分子機能2011
- Author(s)
  清宮啓之
- Organizer
  第84回日本生化学会大会シンポジウム「ADP-リボシル化によるシグナル伝達制御」(招待講演)
- Place of Presentation
  (京都)
- Year and Date
  2011-09-21
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] Involvement of constitutively active truncated androgen receptor(tAR) in hormone-refractory prostate cancer growth and the tAR inhibition by nigericin2011
- Author(s)
  Mashima T., Okabe S., Seimiya H.
- Organizer
  第10回日韓がん老化合同シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22650230
[Presentation] ポリ(ADP-リボシル)化酵素タンキラーゼ1の新たな分子機能2011
- Author(s)
  清宮啓之
- Organizer
  第84回日本生化学会大会シンポジウム「ADP-リボシル化によるシグナル伝達制御」
- Place of Presentation
  国立京都国際会館(京都府)(招待講演)
- Year and Date
  2011-09-21
- Data Source
  KAKENHI-PUBLICLY-23117527
[Presentation] がん治療応用を目指したテロメア研究の現況2011
- Author(s)
  清宮啓之
- Organizer
  医薬ライセンシング協会第236回月例会
- Place of Presentation
  学士会館(東京都)(招待講演)
- Year and Date
  2011-11-15
- Data Source
  KAKENHI-PUBLICLY-23117527
[Presentation] Telomere fingerprinting for drug sensitivity studies and cancer cell biology2011
- Author(s)
  清宮啓之
- Organizer
  ニース大学招待セミナー
- Place of Presentation
  ニース大学(フランス・ニース)(招待講演)
- Year and Date
  2011-11-21
- Data Source
  KAKENHI-PUBLICLY-23117527
[Presentation] ナイジェリシンによる恒常活性化型アンドロゲン受容体の抑制はホルモン再燃性前立腺がん細胞増殖を阻害する2011
- Author(s)
  馬島哲夫、岡部幸子、清宮啓之
- Organizer
  第11回関東ホルモンと癌研究会
- Place of Presentation
  東京
- Year and Date
  2011-01-29
- Data Source
  KAKENHI-PROJECT-22650230
[Presentation] テロメアを起点とした創薬シーズ開発と新たながん生物学研究への展開2011
- Author(s)
  清宮啓之
- Organizer
  愛媛大学第4回分子病態医学セミナー(招待講演)
- Place of Presentation
  (松山)
- Year and Date
  2011-09-07
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] Regulation of chromosome segregation by a telomeric protein TRF12011
- Author(s)
  清宮啓之
- Organizer
  日仏がん研究ワークショップ
- Place of Presentation
  Mercure Montpellier Centre(フランス・モンペリエ)(招待講演)
- Year and Date
  2011-11-22
- Data Source
  KAKENHI-PUBLICLY-23117527
[Presentation] がんとは何でしょう?2011
- Author(s)
  清宮啓之
- Organizer
  新学術領域研究「がん研究分野の特性等を踏まえた支援活動」青少年・市民公開講座～いま知っておきたい「がん」のこと～
- Place of Presentation
  福島県立医科大学(福島県)(招待講演)
- Year and Date
  2011-09-17
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] Regulation of chromosome segregation by a telomeric protein TRF12011
- Author(s)
  清宮啓之
- Organizer
  日仏がん研究ワークショップ
- Place of Presentation
  Mercure Montpellier Centre(フランス・モンペリエ)(招待講演)
- Year and Date
  2011-11-22
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] テロメア制御因子の新たな機能と阻害剤探索2010
- Author(s)
  清宮啓之
- Organizer
  広島大学大学院医歯薬学総合研究科セミナー
- Place of Presentation
  広島
- Year and Date
  2010-01-25
- Data Source
  KAKENHI-PROJECT-20015047
[Presentation] TRF1 mediates mitotic abnormalities induced by Aurora-A overexpression2010
- Author(s)
  清宮啓之
- Organizer
  AACR Special Conference on the Role of Telomerase and Telomeres in Cancer Research
- Place of Presentation
  Fort Worth, USA
- Year and Date
  2010-02-27
- Data Source
  KAKENHI-PROJECT-20015047
[Presentation] 脂質代謝酵素の阻害による制がん効果とその分子メカニズム2010
- Author(s)
  右田敏郎、岡部幸子、清宮啓之
- Organizer
  第14回日本がん分子標的治療学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22650230
[Presentation] 脂質代謝酵素の阻害によるがん細胞死とその分子機構2010
- Author(s)
  右田敏郎、岡部幸子、清宮啓之
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会・ワークショップ
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22650230
[Presentation] TRF1 mediates mitotic abnormalities induced by Aurora-A overexpression2010
- Author(s)
  Seimiya H
- Organizer
  AACR Special Conference on the Role of Telomerase and Telomeres in Cancer Research
- Place of Presentation
  Texas, USA
- Year and Date
  2010-02-27
- Data Source
  KAKENHI-PROJECT-17012025
[Presentation] Telomere fingerprinting for prediction of anticancer drug sensitivities2010
- Author(s)
  清宮啓之
- Organizer
  AACR/JCA Joint Conference : Cancer Genomics, Epigenomics and the Development of Novel Therapeutics
- Place of Presentation
  Hawaii, USA
- Year and Date
  2010-02-09
- Data Source
  KAKENHI-PROJECT-20015047
[Presentation] がん細胞の増殖・生存における脂質代謝酵素の役割2010
- Author(s)
  岡部幸子、右田敏郎、馬島哲夫、清宮啓之
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22650230
[Presentation] Development of telomerase inhibitors and their application to anticancer therapeutics2010
- Author(s)
  Seimiya, H
- Organizer
  Pacifichem 2010
- Place of Presentation
  (Hawaii, USA)
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] 細胞分裂の異常を媒介するテロメア蛋白質2010
- Author(s)
  清宮啓之
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会・ワークショップ
- Place of Presentation
  神戸
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] がん治療応用をめざしたテロメア研究の新展開2010
- Author(s)
  清宮啓之
- Organizer
  東京大学医科学研究所学友会セミナー・GCOE特別セミナー
- Place of Presentation
  東京
- Year and Date
  2010-07-26
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] Development of telomerase inhibitors and their application to anticancer therapeutics2010
- Author(s)
  Seimiya, H.
- Organizer
  Pacifichem 2010
- Place of Presentation
  Hawaii, USA
- Year and Date
  2010-12-15
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] TRF1 mediates mitotic abnormalities induced by Aurora-Aoverexpression2010
- Author(s)
  清宮啓之
- Organizer
  AACR Special Conference on the Role of Telomer ase and Telomeres in Cancer Research
- Place of Presentation
  Fort Worth, USA
- Year and Date
  2010-02-17
- Data Source
  KAKENHI-PROJECT-17012025
[Presentation] 細胞分裂の異常を媒介するテロメア蛋白質2010
- Author(s)
  清宮啓之
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会・ワークショップ
- Place of Presentation
  (神戸)
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] TRF1 mediates mitotic abnormalities induced by Aurora-A overexpression.2010
- Author(s)
  Seimiya, H., Ohishi, H., Hirota, T., Tsuruo, T.
- Organizer
  AACR Special Conference on the Role of Telomerase and Telomeres in Cancer Research
- Place of Presentation
  Fort Worth, USA
- Year and Date
  2010-02-27
- Data Source
  KAKENHI-PROJECT-20015047
[Presentation] がん分子標的治療探索とトランスレーショナルリサーチへの展開2010
- Author(s)
  清宮啓之
- Organizer
  中国・四国広域がんプロ養成コンソーシアム・徳島大学大学院セミナー
- Place of Presentation
  徳島
- Year and Date
  2010-02-03
- Data Source
  KAKENHI-PROJECT-20659024
[Presentation] がん分子標的治療探索とトランスレーショナルリサーチへの展開2010
- Author(s)
  清宮啓之
- Organizer
  中国・四国広域がんプロ養成コンソーシアム・徳島大学大学院セミナー
- Place of Presentation
  徳島
- Year and Date
  2010-02-03
- Data Source
  KAKENHI-PROJECT-20015047
[Presentation] がん治療応用をめざしたテロメア研究の新展開2010
- Author(s)
  清宮啓之
- Organizer
  東京大学医科学研究所・学友会セミナー・GCOE特別セミナー
- Place of Presentation
  (東京)
- Year and Date
  2010-07-26
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] テロメア動態制御ネットワークの解明と薬剤反応性研究への応用2009
- Author(s)
  清宮啓之
- Organizer
  岩手医科大学・化学療法基盤情報支援班共催シンポジウム「抗がん剤創薬の新たな展開」
- Place of Presentation
  岩手
- Year and Date
  2009-01-16
- Data Source
  KAKENHI-PROJECT-19370078
[Presentation] テロメア動態制御ネットワークの解明と薬剤反応性研究への応用2009
- Author(s)
  清宮啓之
- Organizer
  岩手医科大学・化学療法基盤情報支援班共催シンポジウム「抗がん剤創薬の新たな展開」
- Place of Presentation
  岩手
- Year and Date
  2009-01-16
- Data Source
  KAKENHI-PROJECT-19370078
[Presentation] テロメア動態制御ネットワークの解明と薬剤反応性研究への応用・岩手医科大学2009
- Author(s)
  清宮啓之
- Organizer
  化学療法基盤情報支援班共催シンポジウム「抗がん剤創薬の新たな展開」
- Place of Presentation
  岩手
- Year and Date
  2009-01-16
- Data Source
  KAKENHI-PROJECT-20015047
[Presentation] Telomere Fingerprint Database の構築と薬剤反応性研究への応用2009
- Author(s)
  清宮啓之
- Organizer
  第13回日本がん分子標的治療学会学術集会
- Place of Presentation
  徳島
- Year and Date
  2009-06-25
- Data Source
  KAKENHI-PROJECT-20015047
[Presentation] テロメア・老化関連分子を標的とした新規がん化学療法の開発2009
- Author(s)
  清宮啓之
- Organizer
  第1回佐賀大学先端研究センター研究推進部門セミナー「がん分子標的療法の新展開」
- Place of Presentation
  佐賀
- Year and Date
  2009-02-27
- Data Source
  KAKENHI-PROJECT-20015047
[Presentation] テロメア・老化関連分子を標的とした新規がん化学療法の開発2009
- Author(s)
  清宮啓之
- Organizer
  第1回佐賀大学先端研究センター研究推進部門セミナー「がん分子標的療法の新展開」
- Place of Presentation
  佐賀
- Year and Date
  2009-02-27
- Data Source
  KAKENHI-PROJECT-19370078
[Presentation] Telomere fingerprinting and its application to drug sensitivity studies2009
- Author(s)
  Seimiya H
- Organizer
  The 9th Korea-Japan Symposium on Cancer and Ageing Research
- Place of Presentation
  韓国Damyang
- Year and Date
  2009-03-12
- Data Source
  KAKENHI-PROJECT-19370078
[Presentation] Telomere fingerprinting for global prediction of anticancer drug sensitivities2009
- Author(s)
  Seimiya, H.
- Organizer
  Japanese-German Cancer Workshop
- Place of Presentation
  Hamburg, Germany
- Year and Date
  2009-09-17
- Data Source
  KAKENHI-PROJECT-20015047
[Presentation] Telomere maintenance systems as anticancer targets.2009
- Author(s)
  Seimiya, H.
- Organizer
  The 14th Japanese Foundation for Cancer Research-International Symposium on Cancer Chemotherapy
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2009-12-02
- Data Source
  KAKENHI-PROJECT-20015047
[Presentation] ポリ(ADP-リボシル)化酵素タンキラーゼ1の自己多量体化によるテロメア機能の調節2009
- Author(s)
  初谷香織、大石智一、杉本芳一、鶴尾隆、清宮啓之
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-19370078
[Presentation] テロメアの構造的多様性を起点とした薬剤反応性研究2009
- Author(s)
  清宮啓之
- Organizer
  理化学研究所ケミカルバイオロジー研究領域勉強会
- Place of Presentation
  和光
- Year and Date
  2009-04-22
- Data Source
  KAKENHI-PROJECT-20015047
[Presentation] テロメア動態制御ネットワークの解明と薬剤反応性研究への応用2009
- Author(s)
  清宮啓之
- Organizer
  岩手医科大学・化学療法基盤情報支援班共催シンポジウム「抗がん剤創薬の新たな展開」
- Place of Presentation
  岩手
- Year and Date
  2009-01-16
- Data Source
  KAKENHI-PROJECT-20015047
[Presentation] Telomere fingerprinting for global prediction of anticancer drug sensitivities2009
- Author(s)
  清宮啓之
- Organizer
  Cold Spring Harbor Laboratory Meeting on Telomeres & Telomerase
- Place of Presentation
  Cold Spring Harbor, USA
- Year and Date
  2009-04-30
- Data Source
  KAKENHI-PROJECT-20015047
[Presentation] Telomere maintenance systems as anticancer targets2009
- Author(s)
  清宮啓之
- Organizer
  The 14th Japanese Foundation for Cancer Research-International Symposium on Cancer Chemotherapy
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2009-12-02
- Data Source
  KAKENHI-PROJECT-20015047
[Presentation] Telomere fingerprinting and its application to drug sensitivity studies.2009
- Author(s)
  清宮啓之
- Organizer
  The 9th Korea-Japan Symposium on Cancer and Ageing Research.
- Place of Presentation
  韓国, Damyang
- Year and Date
  2009-03-12
- Data Source
  KAKENHI-PROJECT-17012025
[Presentation] Telomere fingerprinting and its application to drug sensitivity studies2009
- Author(s)
  清宮啓之
- Organizer
  The 9th Korea-Japan Symposium on Cancer and Ageing Reseach
- Place of Presentation
  韓国・Damyang
- Year and Date
  2009-03-12
- Data Source
  KAKENHI-PROJECT-20015047
[Presentation] テロメアを標的としたがん治療2009
- Author(s)
  清宮啓之
- Organizer
  第2回富山ライフサイエンスシンポジウム～がんの基礎研究と臨床研究のかけわたし～
- Place of Presentation
  富山
- Year and Date
  2009-07-25
- Data Source
  KAKENHI-PROJECT-20015047
[Presentation] Telomere fingerprinting for global prediction of anticancer drug sensitivities.2009
- Author(s)
  Seimiya, H., Muramatsu, Y., Tokunaga, S., Tahara, H., Ueno, M., Yamori, T., Tsuruo, T.
- Organizer
  Cold Spring Harbor Laboratory Meeting on Telomeres & Telomerase.
- Place of Presentation
  Cold Spring Harbor, USA
- Year and Date
  2009-04-30
- Data Source
  KAKENHI-PROJECT-20015047
[Presentation] Telomere fingerprinting and its application to drug sensitivity studies2009
- Author(s)
  清宮啓之
- Organizer
  The 9th Korea-Japan Symposium on Cancer and Ageing Research
- Place of Presentation
  韓国・Damyang
- Year and Date
  2009-03-12
- Data Source
  KAKENHI-PROJECT-19370078
[Presentation] Telomere fingerprinting and its application to drug sensitivity studies2009
- Author(s)
  Seimiya, H.
- Organizer
  The 9th Korea-Japan Symposium on Cancer and Ageing Research.
- Place of Presentation
  Damyang, Korea
- Year and Date
  2009-03-12
- Data Source
  KAKENHI-PROJECT-20015047
[Presentation] Telomere Fingerprint Databaseの構築と薬剤反応性研究への応用2009
- Author(s)
  清宮啓之、村松由起子、田原栄俊、矢守隆夫、鶴尾隆
- Organizer
  第13回日本がん分子標的治療学会学術集会
- Place of Presentation
  徳島
- Year and Date
  2009-06-25
- Data Source
  KAKENHI-PROJECT-20015047
[Presentation] 細胞分裂におけるテロメア結合蛋白質の新たな機能2008
- Author(s)
  清宮啓之
- Organizer
  第26回日本ヒト細胞学会学術集会
- Place of Presentation
  東京
- Year and Date
  2008-08-30
- Data Source
  KAKENHI-PROJECT-19370078
[Presentation] テロメア伸長がもたらすがん細胞の遺伝子発現変化2008
- Author(s)
  平島匡太郎、鶴尾隆、清宮啓之
- Organizer
  第31回日本分子生物学会年会第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-19370078
[Presentation] Construction of the Telomere Fingerprint Database, a novel platform for telomere dynamics and drug sensitivity studies2008
- Author(s)
  清宮啓之、村松由起子、田原栄俊、上野勝、矢守隆夫、鶴尾隆
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-19370078
[Presentation] Tankyrase 1 suppresses oncogene-induced mitotic abnormalities.2008
- Author(s)
  Seimiya, H., Ohishi, T., Tsuruo, T.
- Organizer
  EMBO Conference on Telomeres and the DNA Damage Response
- Place of Presentation
  Villars-sur-Ollon, Switzerland
- Year and Date
  2008-09-18
- Data Source
  KAKENHI-PROJECT-20015047
[Presentation] Tankyrase 1 suppresses oncogene-induced mitotic abnormalities.2008
- Author(s)
  清宮啓之
- Organizer
  欧州EMBOカンファレンス「Telomeres and the DNA Damage Response」
- Place of Presentation
  スイス・Villars-sur-Ollon
- Year and Date
  2008-09-18
- Data Source
  KAKENHI-PROJECT-20015047
[Presentation] Tankyrase 1 suppresses oncogene-induced mitotic abnormalities.2008
- Author(s)
  清宮啓之, 大石智一, 鶴屋隆
- Organizer
  欧州EMBOカンファレンス「Telomeres and the DNA Damage Response」
- Place of Presentation
  Switzerland, Villars-sur-Ollon
- Year and Date
  2008-09-18
- Data Source
  KAKENHI-PROJECT-17012025
[Presentation] TRF1 mediates mitotic abnormalities induced by Aurora A overexpression2008
- Author(s)
  大石智一、鶴尾隆、清宮啓之
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-19370078
[Presentation] Tankyrase 1 suppresses oncogene-induced mitotic abnormalities2008
- Author(s)
  清宮啓之
- Organizer
  欧州EMBOカンファレンス「Telomeres and the DNA Damage Response」
- Place of Presentation
  スイス・Villars-sur-Ollon
- Year and Date
  2008-09-18
- Data Source
  KAKENHI-PROJECT-19370078
[Presentation] 細胞分裂におけるテロメア結合蛋白質の新たな機能2008
- Author(s)
  清宮啓之
- Organizer
  第26回日本ヒト細胞学会学術集会
- Place of Presentation
  東京
- Year and Date
  2008-08-30
- Data Source
  KAKENHI-PROJECT-20015047
[Presentation] Tankyrase 1 suppresses oncogene-induced mitotic abnormalities2008
- Author(s)
  Seimiya H, Ohishi T, Tsuruo T
- Organizer
  欧州EMBOカンファレンス「Telomeres and the DNA Damage Response」
- Place of Presentation
  スイスVillars-sur-Ollon
- Year and Date
  2008-09-18
- Data Source
  KAKENHI-PROJECT-19370078
[Presentation] Acyl-CoA synthetase as a survival factor of cancer : its inhibition enhances the efficacy of cancer chemotherapy2008
- Author(s)
  清宮啓之
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-20659024
[Presentation] Construction of the Telomere Fingerprint Database, a novel platform for telomere dynamics and drug sensitivity studies.2008
- Author(s)
  清宮啓之、村松由起子、田原栄俊、上野勝、矢守隆夫、鶴尾隆
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-20015047
[Presentation] タンキラーゼ1の細胞分裂における機能的関与2007
- Author(s)
  大石智一、鶴尾隆、清宮啓之
- Organizer
  第11回がん分子標的治療研究会総会
- Place of Presentation
  大阪
- Year and Date
  2007-07-05
- Data Source
  KAKENHI-PROJECT-19370078
[Presentation] Tankyrase 1 suppresses mitotic abnormalities induced by Aurora A overexpression2007
- Author(s)
  Ohishi T, Tsuruo T, Seimiya H
- Organizer
  The 8th Japan-Korea Joint Symposium on Cancer and Ageing Research
- Place of Presentation
  岐阜
- Year and Date
  2007-08-11
- Data Source
  KAKENHI-PROJECT-19370078
[Presentation] Anticancer effect of a telomerase inhibitor,MST-312,associated with telomere length and a premature aging related protein2007
- Author(s)
  Seimiya, H.
- Organizer
  AACR Special Conference "The Role of Telomeres and Telomerase in Cancer Research"
- Place of Presentation
  San Francisco CA,USA
- Year and Date
  2007-12-07
- Data Source
  KAKENHI-PROJECT-19370078
[Presentation] Acute anti-proliferative effect of a synthetic telomerase inhibitor,MST-312,on human cancer cells2007
- Author(s)
  Seimiya, H.
- Organizer
  Cold Spring Harbor Laboratory Meeting on Telomeres&telomerase
- Place of Presentation
  Cold Siring Harbor NY,USA
- Year and Date
  2007-05-04
- Data Source
  KAKENHI-PROJECT-19370078
[Presentation] Cancer therapy by a telomerase inhibitor, MST-3122007
- Author(s)
  清宮啓之, 鶴尾隆.
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-17012025
[Presentation] Anticancer effect of a telomerase inhibitor, MST-312, associated with telomere length and a premature aging-related protein2007
- Author(s)
  Seimiya H, Muramatsu Y, Sato S, Tahara H, Yamori T, Tsuruo T
- Organizer
  AACR Special Conference "The Role of Telomeres and Telomerase in Cancer Research"
- Place of Presentation
  San Francisco, CA, USA
- Year and Date
  2007-12-07
- Data Source
  KAKENHI-PROJECT-19370078
[Presentation] Anticancer effect of a telomerase inhibitor, MST-312, associated with telomere length and a premature aging-related protein2007
- Author(s)
  Seimiya, H.
- Organizer
  AACR Special Conference "The Role of Telomeres and Telomerase in Cancer Research"
- Place of Presentation
  San Francisco CA, USA
- Year and Date
  2007-12-07
- Data Source
  KAKENHI-PROJECT-18015047
[Presentation] Acute anti-proliferative effect of a synthetic telomerase inhibitor, MST-312, on human cancer cells2007
- Author(s)
  Seimiya H, Muramatsu Y, Sato S, Sakamoto M, Ohishi T, Tahara H, Yamori T, Tsuruo T
- Organizer
  Cold Spring Harbor Laboratory Meeting on Telomeres & telomerase
- Place of Presentation
  Cold Spring Harbor, NY, USA
- Year and Date
  2007-05-04
- Data Source
  KAKENHI-PROJECT-19370078
[Presentation] Acute anti-proliferative effect of a synthetic telomerase inhibitor, MST-312, on human cancer cells2007
- Author(s)
  Seimiya, H.
- Organizer
  Cold Spring Harbor Laboratory Meeting on Telomeres & telomerase
- Place of Presentation
  Cold Spring Harbor NY, USA
- Year and Date
  2007-05-04
- Data Source
  KAKENHI-PROJECT-18015047
[Presentation] Intracellular reactions induced by a telomerase inhibitor and their impact on human cancer cell growth.2007
- Author(s)
  清宮啓之, 鶴尾隆.
- Organizer
  The 8th Japan-Korea Joint Symposium on Cancer and Ageing Research
- Place of Presentation
  岐阜
- Year and Date
  2007-08-11
- Data Source
  KAKENHI-PROJECT-17012025
[Presentation] Tankyrase 1 suppresses mitotic abnormalities induced by Aurora A overexpression2007
- Author(s)
  大石智一、鶴尾隆、清宮啓之
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-05
- Data Source
  KAKENHI-PROJECT-19370078
[Presentation] Cancer therapy by a telomerase inhibitor, MST-3122007
- Author(s)
  Seimiya H, Tsuruo T
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-19370078
[Presentation] Intracellular reactions induced by a telomerase inhibitor and their impact on human cancer cell growth2007
- Author(s)
  Seimiya H, Tsuruo T
- Organizer
  The 8th Japan-Korea Joint Symposium on Cancer and Ageing Research
- Place of Presentation
  岐阜
- Year and Date
  2007-08-11
- Data Source
  KAKENHI-PROJECT-19370078
[Presentation] Cross-species difference in telomeric function of tankyrase 12007
- Author(s)
  村松由起子、大石智一、鶴尾隆、清宮啓之
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-05
- Data Source
  KAKENHI-PROJECT-19370078
[Presentation] Cancer therapy by a telomerase inhibitor, MST-3122007
- Author(s)
  Seimiya, H.
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-18015047
[Presentation] Intracellular reactions induced by a telomerase inhibitor and their impact on human cancer cell growth2007
- Author(s)
  Seimiya, H.
- Organizer
  The 8th Japan-Korea Joint Symposium on Cancer and Ageing Research
- Place of Presentation
  岐阜
- Year and Date
  2007-08-11
- Data Source
  KAKENHI-PROJECT-18015047

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# of Collaborated Products: 4 results
155. TANAKA noritaka

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
156. MURAMATSU yukiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
157. SHIMAMOTO Akira

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
158. IIZUKA Katsumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
159. HORIKAWA Yukio

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
160. RYOUHEI Katayama

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
161. KUNIMASA Kazuhiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
162. ITOH Takehiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
163. SAITO Sakae

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
164. ITO Youichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
165. 大石智一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
166. 上野勝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
167. 後藤眞

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
168. 横手幸太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
169. 湯浅慎介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
170. 末永光邦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
171. 武田純

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
172. 飯田圭介

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
173. 曽我朋義

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
174. 入村達郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
175. 佐田政隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
176. 杉山雄一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
177. 西川博嘉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
178. 白髭克彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
179. 椎名勇

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Seimiya Hiroyuki 清宮 啓之

SEIMIYA Hiroyuki 清宮 啓之

清宮 啓之 セイミヤ ヒロユキ

Research Projects

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Co-Researchers

Elucidating the functions of quadruplex nucleic acids by integrative molecular profiling of chemical signalsPrincipal InvestigatorOngoing

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四重鎖核酸の動態攪乱に対するがん細胞選択的脆弱性の分子基盤Principal InvestigatorOngoing

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Optimization of cancer therapeutic strategies that target tankyrase-specific PARylationPrincipal InvestigatorOngoing

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Integrative functional analysis of G-quadruplex nucleic acids by utilizing natural and synthetic chemical tool moleculesPrincipal InvestigatorOngoing

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非典型核酸形態が惹起するがん種横断的脆弱性の分子基盤と治療応用Principal InvestigatorOngoing

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Synthetic lethality-based identification of drug-sensitive genome profilesPrincipal Investigator

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先端モデル動物支援プラットフォームOngoing

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Regulation of cell motility by poly(ADP-ribosyl)ation and its application to overcoming cancer invasion and metastasisPrincipal Investigator

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Development of G-quadruplex ligands that target cancer stem cellsPrincipal Investigator

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Bioinformatics-based functional analysis of telomeric non-coding RNAPrincipal Investigator

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ポリ（ＡＤＰーリボシル）化による細胞の分裂と運動の制御Principal Investigator

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Role of oncogenic factors and their cooperations in survival of prostate tumor-propagating cells

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Scientific Support Programs for Cancer Research Grant-in-Aid for Scientific Research on Innovative Areas

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Seimiya Hiroyuki 清宮啓之

SEIMIYA Hiroyuki 清宮啓之

清宮啓之セイミヤヒロユキ