Kakeya Hideaki 掛谷秀昭

… Alternative Names

Researcher Number	00270596
Other IDs	https://orcid.org/0000-0002-4293-7331
Affiliation (Current)	2020: 京都大学, 薬学研究科, 教授
Affiliation (based on the past Project Information) *help	2016 – 2020: 京都大学, 薬学研究科, 教授 2015: 京都大学, 大学院薬学研究科, 教授 2015: 京都大学, 薬学研究科(研究院), 教授 2013: 京都大学, 大学院・薬学研究科 2007 – 2009: Kyoto University, 薬学研究科, 教授 … More
Review Section/Research Field	Principal Investigator Science and Engineering / Bioorganic chemistry / Bioorganic chemistry / Agricultural chemistry and related fields / Basic Section 37020:Chemistry and chemical methodology of biomolecules-related Except Principal Investigator Science and Engineering / Circulatory organs internal medicine / Biological pharmacy / Bioproduction chemistry/Bioorganic chemistry
Keywords	Principal Investigator ケミカルバイオロジー / 天然物化学 / 複合培養 / 生合成 / 天然有機化合物 / ケミカルゲノミクス / 細胞死 / クリプティック遺伝子 / 化学コミュニケーション / 生物活性リガンド … More Except Principal Investigator ホスファターゼ / VHR / RK-682 / 構造活性相関 / 阻害剤 / Curvularia sp. / phoslactomycin / アポトーシス / isoavenaciolide / 拮抗阻害 / ホスラクトマイシン / RK-1009 / ホスファトキノン / 化学生物学 / 構造生物学 / バイオプローブ / 蛋白質 / 相互作用 / 受容体 / リガンド / 化合物アレイ / ライブラリー / 低分子化合物 / 結晶構造解析 / 標的分子 / マイクロRNA / HDL-C / 動脈硬化 / ABCA1 / SREBP-2 / SREBP-1 / 脂肪肝 / 動脈瘤 / 心肥大 / DNA複製 / DNA修復 / 無細胞系 / 抗がん剤 / サポニン / DNAヘリカーゼ / SV40 T抗原 / DNA replication / DNA repair / cell-free system / inhibitors / anti-cancer drugs / saponin / DNA helicase / SV40T antigen / G1期 / 蛋白質合成阻害 / 細胞周期 / 新規化合物 / セスキテルペン / トリコテセン / 細胞周期阻害剤 / 微小管 / チューブリン / ピロネチン / ビオチン標識 / チユープリン / トリプロスタチン / サイトカラシン / サイクリン / テルペプチン / ホスミドシン / G1 phase / protein synthesis inhibition / cell cycle / new compound / sesquiterpene / trichotecene / 生合成系 / 脱リン酸化 / Bcl-2 / リン酸化 / 4-isoavenaciolide / Michael付加 / 活性中心 / 分子設計 / テトロン酸 / phosphatase / inhibitor / biosynthesis / apoptosis / dephosphorylation / 若手支援 / 国際研究者交流 / 遺伝子改変マウス / 病理形態学 / ゲノムコーホート研究 / 次世代分子解析技術 / アカデミア創薬 / ゲノム・エピゲノム解析支援 / 個別化がん予防 / 国際交流 / ATL発症予防 / 分子疫学コーホート研究 / がん化学予防 / ATL発がん機序 / ATL発症リスク / がん分子標的薬剤 / アンドロゲンアンタゴニスト / オートファジー / βカテニン / アンタルライド / キサントフモール / ノナクチン / 難治疾患 / 天然物リガンド / 作用解析機構 / VCP / がん / パーキンソン病 / 前立腺がん / EMT / 放線菌培養液 / 神経細胞 / MPP Less

Chemical biology on a bioactive substance regulating the hypoxia response signalPrincipal InvestigatorOngoing
- Principal Investigator
  
  掛谷秀昭
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 37020:Chemistry and chemical methodology of biomolecules-related
- Research Institution
  Kyoto University
Frontier research of chemical communicationsArea Organizer
- Area Organizer
  
  掛谷秀昭
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
Frontiers in Chemical CommunicationsPrincipal InvestigatorOngoing
- Principal Investigator
  
  掛谷秀昭
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Kyoto University
Biosynthetic research on cryptic gene activationPrincipal Investigator
- Principal Investigator
  
  Kakeya Hideaki
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Agricultural chemistry and related fields
- Research Institution
  Kyoto University
Chemical communications in microbial interactions and development of useful bioactive ligandsPrincipal InvestigatorOngoing
- Principal Investigator
  
  掛谷秀昭
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Kyoto University
Chemical biology on cryptic genes activationPrincipal Investigator
- Principal Investigator
  
  Kakeya Hideaki
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Bioorganic chemistry
- Research Institution
  Kyoto University
Elucidation of the functions of miR-33a/b in cholesterol homeostasis
- Principal Investigator
  
  ONO KOH
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kyoto University
Discovery of natural products that modulate cellular responses
- Principal Investigator
  
  Imoto Masaya
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Keio University
Scientific Support Programs for Cancer Research Grant-in-Aid for Scientific Research on Innovative Areas
- Principal Investigator
  
  IMAI Kohzoh, 中村祐輔
- Project Period (FY)
  2010 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  The University of Tokyo
Chemical proteomics to reveal interaction between chemicals and proteins at angstrom level
- Principal Investigator
  
  OSADA Hiroyuki
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Creative Scientific Research
- Research Institution
  The Institute of Physical and Chemical Research
微生物代謝産物由来の機能性天然分子の探索・創製と応用研究Principal Investigator
- Principal Investigator
  
  掛谷秀昭
- Project Period (FY)
  2004 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Kyoto University
  The Institute of Physical and Chemical Research
細胞死を制御する天然有機化合物の化学生物学的解析Principal Investigator
- Principal Investigator
  
  掛谷秀昭
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  The Institute of Physical and Chemical Research
Chemical biology study on protein phosphatases and their specific inhibitors.
- Principal Investigator
  
  OSADA Hiroyuki
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  RIKEN
デュアルスペシフィックホスファターゼの阻害剤開発と機能探索
- Principal Investigator
  
  長田裕之
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  The Institute of Physical and Chemical Research
デュアルスペシフィックホスファターゼの阻害剤開発と機能探索
- Principal Investigator
  
  OSADA Hiroyuki
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The Institute of Physical and Chemical Research
神経芽腫細胞における神経細胞分化誘導とテロメラーゼ活性に関する研究Principal Investigator
- Principal Investigator
  
  掛谷秀昭
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  The Institute of Physical and Chemical Research
Isolation and mechanism study of cell cycle inhibitors from microbial metabolites.
- Principal Investigator
  
  OSADA Hiroyuki
- Project Period (FY)
  1997 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Bioproduction chemistry/Bioorganic chemistry
- Research Institution
  RIKEN
Search for Novel Anti-cancer Drugs Targetting DNA Replication and Repair
- Principal Investigator
  
  HANAOKA Fumio
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Osaka University

[Book] 1. 薬の基礎知識 & 2. 創薬の世界, Newton 別冊「くすりの科学知識：くすりのしくみと、奥深き創薬の世界」2017
- Author(s)
  掛谷秀昭（監修）
- Total Pages
  144
- Publisher
  ニュートンプレス社
- ISBN
  9784315520835
- Data Source
  KAKENHI-PLANNED-17H06401
[Book] 1. 薬の基礎知識 & 2. 創薬の世界, Newton 別冊「くすりの科学知識：くすりのしくみと、奥深き創薬の世界」2017
- Author(s)
  掛谷秀昭（監修）
- Total Pages
  144
- Publisher
  ニュートンプレス社
- ISBN
  9784315520835
- Data Source
  KAKENHI-PROJECT-17K19233
[Book] 特集・制がん剤の分子標的スクリーニング成績「化学療法基盤情報支援班」報告‐制がん候補物質のスクリーニング成績・第15報『癌と化学療法オンライン』2013
- Author(s)
  矢守隆夫, 上原至雅, 深澤秀輔, 吉田稔, 井本正哉, 清宮啓之, 馬島哲夫, 水上民夫, 川田学, 長田裕之, 旦慎吾, 松浦正明, 掛谷秀昭, 冨田章弘.
- Publisher
  癌と化学療法社
- Data Source
  KAKENHI-PROJECT-221S0001
[Book] 特集・制がん剤の分子標的スクリーニング成績化学療法基盤支援活動報告-制がん候補物質のスクリーニング成績・第15報2013
- Author(s)
  矢守隆夫, 上原至雅, 深澤秀輔, 吉田稔, 井本正哉, 清宮啓之, 馬島哲夫, 水上民夫, 川田学, 長田裕之, 旦慎吾, 松浦正明, 掛谷秀昭, 冨田章弘
- Publisher
  癌と化学療法社
- Data Source
  KAKENHI-PROJECT-221S0001
[Book] インシリコ創薬科学 -ゲノム情報から創薬へ-「創薬研究における化合物ライブラリー」2008
- Author(s)
  掛谷秀昭, 他
- Total Pages
  210
- Publisher
  京都廣川書店
- Data Source
  KAKENHI-PROJECT-17GS0221
[Journal Article] Identification of the common biosynthetic gene cluster forboth antimicrobial streptoaminals and antifungal 5-alkyl-1,2,3,4-tetrahydroquinolines.2019
- Author(s)
  Ozaki Taro、Sugiyama Ryosuke、Shimomura Morito、Nishimura Shinichi、Asamizu Shumpei、Katsuyama Yohei、Kakeya Hideaki、Onaka Hiroyasu
- Journal Title
  
  Org. Biomol. Chem.
  
  Volume: 17 Pages: 2370-2378
- DOI
  10.1039/c8ob02846j
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05385, KAKENHI-PLANNED-16H06444, KAKENHI-PLANNED-17H06401, KAKENHI-PROJECT-18H02120, KAKENHI-PROJECT-17K19233
[Journal Article] Theonellamide A, a marine-sponge-derived bicyclic peptide, binds to sterol in aqueous DMSO: Solution NMR-based analysis of peptide-sterol interactions using hydroxylated cholesterol.2019
- Author(s)
  Cornelio Kimberly、Espiritu Rafael Atillo、Hanashima Shinya、Todokoro Yasuto、Malabed Raymond、Kinoshita Masanao、Matsumori Nobuaki、Murata Michio、Nishimura Shinichi、Kakeya Hideaki、Yoshida Minoru、Matsunaga Shigeki
- Journal Title
  
  Biochim. Biophys. Acta
  
  Volume: 1861 Pages: 228-235
- DOI
  10.1016/j.bbamem.2018.07.010
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19149, KAKENHI-PLANNED-17H06401, KAKENHI-PLANNED-17H06406, KAKENHI-PLANNED-18H05503, KAKENHI-PROJECT-16H06315, KAKENHI-PUBLICLY-16H00773, KAKENHI-PROJECT-15H03121
[Journal Article] Development of an anti-hepatitisB virus (HBV) agent through the structure-activity relationship of theinterferon-like small compound CDM-30082019
- Author(s)
  Nobuaki Takahashi, Kyohei Hayashi, Yusuke Nakagawa, Yutaka Furutani, Mariko Toguchi, Yumi Shiozaki-Sato, Masayuki Sudoh, Soichi Kojima, Hideaki Kakeya
- Journal Title
  
  10.1016/j.bmc.2018.11.039
  
  Volume: 27 Pages: 470-478
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06401
[Journal Article] Enhancement of saccharothriolide production and discovery of a new metabolite, saccharothriolide C2, by combined-culture of Saccharothrix sp. and Tsukamurella pulmonis2019
- Author(s)
  Yulu Jiang, Shan Lu, Go Hirai, Taira Kato, Hiroyasu Onaka, Hideaki Kakeya
- Journal Title
  
  Tetrahedron Lett.
  
  Volume: 60 Pages: 1072-1074
- DOI
  10.1016/j.tetlet.2019.03.034
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06401, KAKENHI-PROJECT-17K19233
[Journal Article] 研究トピックス：微生物間化学コミュニケーションの利活用によるケミカルスペース拡充戦略2019
- Author(s)
  掛谷秀昭
- Journal Title
  
  新学術領域研究「化学コミュニケーションのフロンティア」・Newsletter
  
  Volume: 3 Pages: 9-9
- Data Source
  KAKENHI-PLANNED-17H06401
[Journal Article] 研究トピックス：がんと宿主の化学コミュニケーション阻害を指向した水溶性プロドラッグ型抗がん剤CMGの開発研究2019
- Author(s)
  掛谷秀昭
- Journal Title
  
  新学術領域研究「化学コミュニケーションのフロンティア」・Newsletter
  
  Volume: 3 Pages: 10-10
- Data Source
  KAKENHI-PLANNED-17H06401
[Journal Article] Curcumin and its demethoxyderivatives possess p300 HAT inhibitory activity and suppress hypertrophicresponses in cardiomyocytes.2018
- Author(s)
  Yoichi Sunagawa, Masafumi Funamoto, Shogo Sono, Kana Shimizu, Satoshi Shimizu, Mai Genpei, Yusuke Miyazaki, Yasufumi Katanasaka, Eriko Morimoto, Morio Ueno, Maki Komiyama, Hideaki Kakeya, Hiromichi Wada, Koji Hasegawa, Tasuya Morimoto
- Journal Title
  
  J. Pharmacol. Sci.
  
  Volume: 136 Pages: 212-217
- DOI
  10.1016/j.jphs.2017.12.013
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06401
[Journal Article] Discovery of presaccharothriolide X, a retro-Michael product of saccharothriolide B, from the rare actinomycete Saccharothrix sp. A15062018
- Author(s)
  Shan Lu, Shinichi Nishimura, Kei Takenaka, Masashi Ito, Taira Kato, Hideaki Kakeya
- Journal Title
  
  Org. Lett.
  
  Volume: 20 Pages: 4406-4410
- DOI
  10.1021/acs.orglett.8b01535
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06401, KAKENHI-PROJECT-17K19233
[Journal Article] Natural products-inspired chemical biology toward developmentof new antibiotics2018
- Author(s)
  Hideaki Kakeya
- Journal Title
  
  Jpn. J. Antibiot.
  
  Volume: 71 Pages: 181-191
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06401
[Journal Article] Natural products-inspired chemical biology toward developmentof new antibiotics2018
- Author(s)
  Hideaki Kakeya
- Journal Title
  
  Jpn. J. Antibiot.
  
  Volume: 71 Pages: 181-191
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19233
[Journal Article] 生体膜を標的にする天然有機化合物：天然物による厳密な脂質認識とそれに基づく表現型2018
- Author(s)
  西村慎一, 掛谷秀昭, 松森信明
- Journal Title
  
  化学と生物
  
  Volume: 56 Pages: 678-685
- NAID
  40021695391
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19233
[Journal Article] Discovery Scienceに魅せられて：天然物創薬ケミカルバイオロジーの最前線2018
- Author(s)
  掛谷秀昭
- Journal Title
  
  化学と生物
  
  Volume: 56 Pages: 210-216
- NAID
  130007601848
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19233
[Journal Article] 生体膜を標的にする天然有機化合物：天然物による厳密な脂質認識とそれに基づく表現型2018
- Author(s)
  西村慎一, 掛谷秀昭, 松森信明
- Journal Title
  
  化学と生物
  
  Volume: 56 Pages: 678-685
- NAID
  40021695391
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06401
[Journal Article] Activity-based protein profiling of non-ribosomal peptide synthetases.2018
- Author(s)
  Ishikawa Fumihiro、Tanabe Genzoh、Kakeya Hideaki
- Journal Title
  
  Curr. Top. Microbiol. Immunol.
  
  Volume: 420 Pages: 321-349
- DOI
  10.1007/82_2018_133
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-17H05438, KAKENHI-PLANNED-17H06401
[Journal Article] 創薬ケミカルバイオロジー：自然に学ぶ薬づくり2017
- Author(s)
  掛谷秀昭
- Journal Title
  
  「くすりをつくる研究者の仕事―薬のタネ探しから私たちに届くまで」
  
  Volume: - Pages: 63-82
- Data Source
  KAKENHI-PROJECT-15K14721
[Journal Article] Visualizing the adenylation activities and protein-protein interactions of aryl acid adenylating enzymes.2017
- Author(s)
  Ishikawa, F., Kasai, S., Kakeya, H., Tanabe, G.
- Journal Title
  
  ChemBioChem.
  
  Volume: 18 Pages: 2199-2204
- DOI
  10.1002/cbic.201700361
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-17H05438, KAKENHI-PLANNED-17H06401
[Journal Article] Curcumin β-D-Glucuronide Plays an Important Role to Keep High Levels of Free-Form Curcumin in the Blood2017
- Author(s)
  Ozawa, H., Imaizumi, A., Sumi, Y., Hashimoto, T., Kanai, M., Makino, Y., Tsuda, T., Takahashi, N., Kakeya, H.
- Journal Title
  
  Biol. Pharm. Bull.
  
  Volume: 40 Issue: 9 Pages: 1515-1524
- DOI
  10.1248/bpb.b17-00339
- NAID
  130006038773
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07804, KAKENHI-PLANNED-17H06401
[Journal Article] A chemoproteomics approach to investigate phosphopantetheine transferase activity at the cellular level.2017
- Author(s)
  Konno, S., Ishikawa, F., Suzuki, T., Dohmae, N., Kakeya, H., Tanabe, G.
- Journal Title
  
  ChemBioChem.
  
  Volume: 18 Pages: 1855-1862
- DOI
  10.1002/cbic.201700301
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-17H05438, KAKENHI-PLANNED-17H06401
[Journal Article] Precursor-directed in situ synthesis of saccharothriolides G and H by the actinomycete Saccharothrix sp.2017
- Author(s)
  Shan Lu, Shinich Nishimura, Masashi Ito, Taira Kato, Hideaki Kakeya
- Journal Title
  
  J. Antibiot.
  
  Volume: 70 Pages: 718-720
- DOI
  10.1038/ja.2016.153
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19233, KAKENHI-PLANNED-17H06401
[Journal Article] Natural products-prompted chemical biology: phenotypic screening and a new platform for target identification2016
- Author(s)
  Kakeya, H.
- Journal Title
  
  Nat. Prod. Rep.
  
  Volume: 33 Pages: 648-654
- DOI
  10.1039/c5np00120j
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K14721
[Journal Article] Discovery and Total Synthesis of Streptoaminals: Antimicrobial [5,5]-Spirohemiaminals from the Combined-Culture of Streptomyces nigrescens and Tsukamurella pulmonis.2016
- Author(s)
  Sugiyama R, Nishimura S, Ozaki T, Asamizu S, Onaka H, Kakeya H.
- Journal Title
  
  Angew. Chem. Int. Ed.
  
  Volume: 55(35) Pages: 10278-10282
- DOI
  10.1002/anie.201604126
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25292046, KAKENHI-PROJECT-25702048, KAKENHI-PROJECT-15K14721, KAKENHI-PROJECT-16K18673
[Journal Article] 感染症の脅威と闘う―ヒトマイクロバイオームと特殊培養デバイスの活用2016
- Author(s)
  都築健悟, 掛谷秀昭
- Journal Title
  
  化学
  
  Volume: 71 Pages: 70-71
- Data Source
  KAKENHI-PROJECT-15K14721
[Journal Article] 5-alkyl-1,2,3,4-tetrahydroquinolines, new membrane-interacting lipophilic metabolites produced by combined culture of Streptomyces nigrescens and Tsukamurella pulmonis2015
- Author(s)
  Sugiyama R, Nishimura S, Ozaki T, Asamizu S, Onaka H, Kakeya H.
- Journal Title
  
  Org. Lett.
  
  Volume: 印刷中 Pages: 1918-1921
- DOI
  10.1021/acs.orglett.5b00607
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25292046, KAKENHI-PROJECT-25702048, KAKENHI-PUBLICLY-26102726, KAKENHI-PROJECT-26850044, KAKENHI-PROJECT-15K14721
[Journal Article] Design, synthesis and structure-activity relationships of 1-ethylpyrazole-3-carboxamide as novel HIF-1 inhibitors2015
- Author(s)
  Yasuda Y, Arakawa T, Nawata Y, Shimada S, Oishi S, Fujii N, Nishimura S, Hattori A, Kakeya H
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 23
- DOI
  10.1016/j.bmc.2015.02.038
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-221S0001
[Journal Article] 生体膜微小環境への挑戦：膜ステロールに作用する海洋天然物セオネラミド2015
- Author(s)
  西村慎一, 掛谷秀昭
- Journal Title
  
  CSJカレントレビュー19号（日本化学会編）「生物活性分子のケミカルバイオロジー」
  
  Volume: 19 Pages: 102-108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K14721
[Journal Article] 創薬ケミカルバイオロジー：シード分子開発と分子プロファイリング2015
- Author(s)
  掛谷秀昭
- Journal Title
  
  生体の科学
  
  Volume: 66 Pages: 119-125
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K14721
[Journal Article] Chemical tagging of a drug target using 5-sulfonyl tetrazole.2013
- Author(s)
  Otsuki S, Nishimura S, Takabatake H, Nakajima K, Takasu Y, Yagura T, Sakai Y, Hattori A, & Kakeya H
- Journal Title
  
  Bioorg Med Chem. Lettt.
  
  Volume: 23 Pages: 1608-1611
- DOI
  10.1016/j.bmcl.2013.01.092
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310160, KAKENHI-PROJECT-24659099, KAKENHI-PROJECT-221S0001
[Journal Article] 特集号「日本の天然物化学の展望-生命科学解明の機能分子、新たな創薬分子として-」;新規有用天然有機化合物の開拓とケミカルバイオロジー研究2010
- Author(s)
  掛谷秀昭, et al
- Journal Title
  
  有機合成化学協会誌
  
  Volume: 68 Pages: 490-500
- Data Source
  KAKENHI-PROJECT-221S0001
[Journal Article] Identification of cytochrome P450s required for fumitremorgin biosynthesis in Aspergillus fumigatus.2009
- Author(s)
  Kakeya, H. (10名中5番目), Usui, T. (10名中7番目), Takahashi, S. (10名中8番目), Osada, H. (10名中10番目)
- Journal Title
  
  Chembiochem 23
  
  Pages: 920-928
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17GS0221
[Journal Article] Fungal metabolite, epoxyquinol B crosslinks proteins by epoxyquinol-thiol conjugation.2008
- Author(s)
  H. Kamiyama, T. Usui, M. Uramoto, H. Takagi, M. Shoji, Y. Hayashi, H. Kakeya, H. Osada
- Journal Title
  
  J. Antibiot. 61
  
  Pages: 94-97
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16073223
[Journal Article] A fungal metabolite, epoxyquinol B inhibits the NF-kappaB signal through the crosslinking of TAK1.2008
- Author(s)
  Usui, T. (7名中2番目), Hayashi, Y. (7名中5番目), Kakeya, H. (7名中6番目), Osada, H. (7名中7番目)
- Journal Title
  
  Biosci. Biotechnol. Biochem. 72
  
  Pages: 1894-1900
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17GS0221
[Journal Article] The asymmetric total synthesis of (+)-cytotrienin A, an ansamycin-type anticancer drug.2008
- Author(s)
  Hayashi, Y. (10名中1番目), Kakeya, H. (10名中9番目), Osada, H. (10名中10番目)
- Journal Title
  
  Angew. Chem. Int. Ed. 47
  
  Pages: 6657-6660
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17GS0221
[Journal Article] Azaspirene, a fungal product, inhibits angiogenesis by blocking Raf-1 activation.2008
- Author(s)
  Kakeya, H. (8名中2番目), Kojima, S. (8名中4番目), Osada, H. (8名中8番目)
- Journal Title
  
  Cancer Sci. 99
  
  Pages: 1853-1858
- NAID
  10024011306
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17GS0221
[Journal Article] Epoxyquinol B shows antiangiogenic effects by inhibiting not only VEGFR2 but also EGFR, FGFR, and PDGFR.2008
- Author(s)
  Kakeya, H. (7名中2番目), Usui, T. (7名中3番目), Hayashi, Y. (7名中6番目), Osada, H. (7名中7番目)
- Journal Title
  
  Oncol. Res. 17
  
  Pages: 11-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17GS0221
[Journal Article] Epoxyquinol B shows antiangiogenic effects in vitro and in vivo byinhibiting VEGFR, and EGFR, FGFR, and PDFR.2008
- Author(s)
  H. Kamiyama, H. Kakeya, T. Usui, K. Nishikawa, M. Shoji, Y. Hayashi, H. Osada
- Journal Title
  
  Oncol. Res.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16073223
[Journal Article] Fungal metabolite, epoxyquinol B, crosslinks proteins by epoxy-thiol conjugation.2008
- Author(s)
  Usui, T. (8名中2番目), Hayashi, Y. (8名中6番目), Kakeya, H. (8名中7番目), Osada, H. (8名中8番目)
- Journal Title
  
  J. Antibiot. 61
  
  Pages: 94-97
- NAID
  80019478123
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17GS0221
[Journal Article] Synthesis and structure-activity relationship studies on tryprostatin A, an inhibitor of breast cancer resistance protein.2008
- Author(s)
  Kakeya, H. (15名中13番目), Osada, H. (15名中14番目)
- Journal Title
  
  Bioorg. Med. Chem. 16
  
  Pages: 4626-4651
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17GS0221
[Journal Article] 微生物が生産する新規生理活性物質の開拓とケミカルバイオロジー研究2007
- Author(s)
  掛谷秀昭
- Journal Title
  
  Jpn. J. Antibiot. 60
  
  Pages: 181-187
- Data Source
  KAKENHI-PROJECT-16073223
[Journal Article] 微生物代謝産物由来の小分子ライブラリーの利用技術-スクリーニングとケミカルバイオロジー研究-2007
- Author(s)
  掛谷秀昭、齋藤安貴子、長田裕之
- Journal Title
  
  BIO INDUSTRY 24
  
  Pages: 48-54
- Data Source
  KAKENHI-PROJECT-16073223
[Journal Article] A bridge between chemistry and biology2006
- Author(s)
  Kikuchi, K., Kakeya, H.
- Journal Title
  
  Nature Chem. Biol. 2
  
  Pages: 392-394
- Data Source
  KAKENHI-PROJECT-16073223
[Journal Article] Epoxytwinol A, a novel unique angiogenesis inhibitor with C_2 symmetry, produced by a fungus2005
- Author(s)
  Kakeya, H. et al.
- Journal Title
  
  Chem.Commun. 2005
  
  Pages: 2575-2577
- Data Source
  KAKENHI-PROJECT-16073223
[Journal Article] Epoxytwinol A, a novel unique angiogenesis inhibitor with C_2 symmetru, produced by a fungus.2005
- Author(s)
  H.Kakeya et al.
- Journal Title
  
  Chem. Commun. 2005
  
  Pages: 2575-2577
- Data Source
  KAKENHI-PROJECT-17GS0221
[Journal Article] 血管内皮増殖因子(VEGF)の機能を標的とした新規血管新生阻害剤2004
- Author(s)
  掛谷秀昭
- Journal Title
  
  日本臨床 62
  
  Pages: 1264-1270
- Data Source
  KAKENHI-PROJECT-16073223
[Presentation] 化学コミュニケーションが織りなす生命科学2019
- Author(s)
  掛谷秀昭
- Organizer
  日本化学会第99春季年会（2019, 神戸）
- Invited
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] 天然物創薬の復権を期して：微生物間化学コミュニケーションの利活用2019
- Author(s)
  掛谷秀昭
- Organizer
  第402回CBI学会（情報計算化学生物学会）講演会（東京）
- Invited
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] 低酸素応答シグナルを標的とした創薬ケミカルバイオロジー2019
- Author(s)
  掛谷秀昭
- Organizer
  日本薬学会第139年会（千葉）
- Invited
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] Towards thedevelopment of chemical communication molecules among microbes.2019
- Author(s)
  Yulu Jiang, Shan Lu, Go Hirai, Taira Kato, Hiroyasu Onaka, Hideaki Kakeya
- Organizer
  The 1st International Symposium on Chemical Communication (ISCC2019, Tokyo)
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] Developmentof an innovative water-soluble anticancer drug, curcumin mono-beta-D-glucuronide(CMG)2019
- Author(s)
  Hideaki Kakeya, Nobuaki Takahashi, Atsuhiro Kishimoto, Atsushi Imaizumi, Masashi Kanai
- Organizer
  The 1st International Symposium on Chemical Communication (ISCC2019, Tokyo)
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] Development of cryptic antifungal 5aTHQs targeting cell membranesignaling2019
- Author(s)
  Hideaki Kakeya
- Organizer
  Asian Chemical Biology Initiative (ACBI) 2019 Yangon Meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] 化学コミュニケーションが織りなす生命科学2019
- Author(s)
  掛谷秀昭
- Organizer
  日本化学会第99春季年会（2019）
- Invited
- Data Source
  KAKENHI-PROJECT-17K19233
[Presentation] Development of cryptic antifungal 5aTHQs targting cell membranesignaling2019
- Author(s)
  Hideaki Kakeya
- Organizer
  Asian Chemical Biology Initiative (ACBI) 2019 Yangon Meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19233
[Presentation] 天然物創薬ケミカルバイオロジーの醍醐味2018
- Author(s)
  掛谷秀昭
- Organizer
  第53回天然物化学談話会
- Invited
- Data Source
  KAKENHI-PROJECT-17K19233
[Presentation] Expansion of chemical space in saccharothriolides: Precursor-directed in situ synthesis (PDSS) in a rare actinomycete Saccharothrix sp2018
- Author(s)
  Shan Lu, Shinichi Nishimura, Masashi Ito, Taira Kato, Hideaki Kakeya
- Organizer
  Natural Product Discovey & Development in the Genomic Era (Natural Products 2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] 天然物創薬ケミカルバイオロジー2018
- Author(s)
  掛谷秀昭, 野中元裕, 倉永健史
- Organizer
  京都大学アカデミックデイ2018
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] 微生物間化学コミュニケーションの利活用によるケミカルスペース拡充戦略2018
- Author(s)
  掛谷秀昭
- Organizer
  新学術領域研究「化学コミュニケーションのフロンティア」・第2回公開シンポジウム
- Invited
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] 「シンポジウム：これからの天然物サイエンス」―ケミカルスペース拡充戦略：微生物複合培養法及びPDSS (Precurso-Directed in situ Synthesis)法―2018
- Author(s)
  掛谷秀昭
- Organizer
  日本農芸化学会2018年度大会
- Invited
- Data Source
  KAKENHI-PROJECT-17K19233
[Presentation] Expansion of chemical space in saccharothriolides: Precursor-directed in situ synthesis (PDSS) in a rare actinomycete Saccharothrix sp.2018
- Author(s)
  Shan Lu, Shinichi Nishimura, Masashi Ito, Taira Kato, Hideaki Kakeya
- Organizer
  Natural Product Discovey & Development in the Genomic Era (Natural Products 2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19233
[Presentation] 医薬品シード分子の多様性創出と細胞内標的探索・同定2018
- Author(s)
  掛谷秀昭
- Organizer
  京大テックフォーラム（東京）
- Invited
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] Development of a water-soluble curcuminmonoglucronide (CMG) as a novel anticancer prodrug targeting KRAS-NF-kappaB signaling pathway2018
- Author(s)
  Kanai, M., Imaizumi, A., Kakeya, H
- Organizer
  Global Academic Programs (GAP) conference (Stockholm, Sweden)
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] Drug delivery to malignant brain tumorby a peptide specific to Annexin A12018
- Author(s)
  Motohiro Nonaka, Hideaki Kakeya, Michiko Fukuda.
- Organizer
  30th EORTC-NCI-AACRSymposium: International Conference on Molecular Targets and Cancer Therapeutics (Dublin)
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] 天然物創薬ケミカルバイオロジーの醍醐味2018
- Author(s)
  掛谷秀昭
- Organizer
  第53回天然物化学談話会（大阪）
- Invited
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] 微生物間化学コミュニケーションの理解と有用生物活性リガンドの開発2018
- Author(s)
  掛谷秀昭, 西村慎一, 倉永健史, 野中元裕, 井本正哉
- Organizer
  新学術領域研究「化学コミュニケーションのフロンティア」・第3回公開シンポジウム（東京）
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] 「中長期企画・ケミカルバイオロジー研究加速のための生物活性分子の発見戦略」―微生物間化学コミュニケーションの謎に挑む―2018
- Author(s)
  掛谷秀昭
- Organizer
  日本化学会第98春季年会（2018）
- Invited
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] 微生物の複合培養で得られる5aTHQの膜親和性と生物活性. 第60回天然有機化合物討論会2018
- Author(s)
  西村慎一, 杉山龍介, 仲谷崇宏, 尾崎太郎, 浅水俊平, 尾仲宏康, 掛谷秀昭
- Organizer
  第60回天然有機化合物討論会（福岡）
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] Microbial metabolites targeting microenvironment: a cell membranesigaling modulator and a hypoxia-response modulator2018
- Author(s)
  Hideaki Kakeya
- Organizer
  The 9th Japan-Koreachemical biology symposium (Inchon, Korea)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] 多隔壁形成や細胞伸長におけるスフィンゴ脂質の重要性2018
- Author(s)
  生田実沙, 伊藤愛理, 西村慎一, 吉田稔, 掛谷秀昭
- Organizer
  酵母遺伝学フォーーラム第51回研究報告会（福岡）
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] アポトーシス誘導活性天然物cytotrieninAの合成研究2018
- Author(s)
  岩渕好治, 佐藤亮, 笹野裕介, 小松慎吾, 野口正嗣, 掛谷秀昭, 長田裕之, 叶直樹
- Organizer
  第60回天然有機化合物討論会（福岡）
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] Microbial metabolites targeting microenvironment: a cell membranesigaling modulator and a hypoxia-response modulator2018
- Author(s)
  Hideaki Kakeya
- Organizer
  The 9th Japan-Koreachemical biology symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19233
[Presentation] 「化学コミュニケーションのフロンティア」を起点にした創薬ケミカルバイオロジー2018
- Author(s)
  掛谷秀昭
- Organizer
  新学術領域研究「脂質クオリティが解き明かす生命現象」第4回領域会議
- Invited
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] Rapid screening of antibody-bindingpeptides by combination of T7 phage display and next-generation sequencingtechnologies2018
- Author(s)
  Motohiro Nonaka, Michiko Fukuda, Hideaki Kakeya
- Organizer
  The 1st International Symposium on Chemical Communication (ISCC2019, Tokyo)
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] 「シンポジウム：これからの天然物サイエンス」―ケミカルスペース拡充戦略：微生物複合培養法及びPDSS (Precurso-Directed in situ Synthesis)法―2018
- Author(s)
  掛谷秀昭
- Organizer
  日本農芸化学会2018年度大会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] 天然物創薬ケミカルバイオロジー～放線菌に魅せられて～2018
- Author(s)
  掛谷秀昭
- Organizer
  2018年度（第33回）日本放線菌学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-17K19233
[Presentation] 医薬品シード分子の多様性創出と細胞内標的探索・同定2018
- Author(s)
  掛谷秀昭
- Organizer
  京大テックフォーラム
- Invited
- Data Source
  KAKENHI-PROJECT-17K19233
[Presentation] Development of a syntheticwater-soluble curcumin mono-beta-D-glucuronide (CMG), as an innovativeanticancer prodrug targeting KRAS-NF-kappaB signaling pathway2018
- Author(s)
  Hideaki Kakeya, Atsuhiro Kishimoto, Atsushi Imaizumi, Masashi Kanai
- Organizer
  30th EORTC-NCI-AACRSymposium: International Conference on Molecular Targets and Cancer Therapeutics (Dublin)
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] 創薬ケミカルバイオロジー研究方略：表現型スクリーニングとシード分子開発2017
- Author(s)
  掛谷秀昭
- Organizer
  ビッグデータ駆動型創薬システム研究拠点・第3回シンポジウム
- Place of Presentation
  横浜
- Year and Date
  2017-03-07
- Invited
- Data Source
  KAKENHI-PROJECT-15K14721
[Presentation] 創農薬イノベーションを創発するケミカルバイオロジー方略2017
- Author(s)
  掛谷秀昭
- Organizer
  農薬デザイン研究会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] アカデミア創薬における表現型スクリーニングと次世代天然物化学2017
- Author(s)
  掛谷秀昭
- Organizer
  日本農芸化学会2017年度大会
- Place of Presentation
  京都
- Year and Date
  2017-03-18
- Invited
- Data Source
  KAKENHI-PROJECT-15K14721
[Presentation] 新しい抗真菌薬シード開発と適応拡大戦略」―抗真菌薬開発のためのケミカルバイオロジー研究方略：シード分子開発とメカニズム解析2017
- Author(s)
  掛谷秀昭
- Organizer
  技術情報協会セミナー
- Place of Presentation
  東京
- Year and Date
  2017-08-02
- Invited
- Data Source
  KAKENHI-PROJECT-15K14721
[Presentation] 機能性食品素材の医薬品への展開を目指した創薬ケミカルバイオロジー2017
- Author(s)
  今泉厚, 高橋伸明, 光金英宣, 金井雅史, 橋本正, 牧野悠治, 津田孝範, 掛谷秀昭
- Organizer
  第7回食品薬学シンポジウム
- Invited
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] 微生物の複合培養で得られる5aTHQとstreptoaminalの構造と構造2016
- Author(s)
  西村慎一, 杉山龍介, 仲谷崇宏, 尾崎太郎, 浅水俊平, 尾仲宏康, 掛谷秀昭
- Organizer
  第21回天然薬物の開発と応用シンポジウム
- Place of Presentation
  千葉
- Year and Date
  2016-10-27
- Invited
- Data Source
  KAKENHI-PROJECT-15K14721
[Presentation] Microbial metabolites-prompted chemical biology: Phenotypic screening and a new platform for target identification2016
- Author(s)
  Kakeya, H
- Organizer
  The Fifth Symposium of RIKEN-Max Planck Joint Research Center for System Chemical Biology
- Place of Presentation
  Germany
- Year and Date
  2016-04-17
- Invited
- Data Source
  KAKENHI-PROJECT-15K14721
[Presentation] 脂質結合性天然物の活用―放線菌複合培養液より見出した新規アルカロイド群に関する研究2016
- Author(s)
  杉山龍介, 西村慎一, 尾崎太郎, 浅水俊平, 尾仲宏康, 掛谷秀昭
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-27
- Invited
- Data Source
  KAKENHI-PROJECT-15K14721
[Presentation] 5-Alkyl-1,2,3,4-tetrahydroquinolines (5aTHQs), new membrane-interacting lipophilic metabolites, produced by combined-culture of Streptomyces nigrescens and Tsukamurella pulmonis2015
- Author(s)
  Sugiyama, R., Nishimura, S., Ozaki, T., Asamizu, S., Onaka, H., Kakeya, H.
- Organizer
  The International Chemical Congress of Pacific Basin Societies 2015 (PACIFICHEM 2015)
- Place of Presentation
  Hawaii, USA
- Year and Date
  2015-12-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14721
[Presentation] Natural products-prompted chemical biology; Phenotypic screening and target identification2015
- Author(s)
  Kakeya, H.
- Organizer
  The International Chemical Congress of Pacific Basin Societies 2015 (PACIFICHEM 2015)
- Place of Presentation
  Hawaii, USA
- Year and Date
  2015-12-15
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14721
[Presentation] シンポジウム「創薬の将来」. 創薬ケミカルバイオロジー：シード分子開発と分子プロファイリング2015
- Author(s)
  掛谷秀昭
- Organizer
  第63回日本化学療法学会総会
- Place of Presentation
  東京
- Year and Date
  2015-06-05
- Invited
- Data Source
  KAKENHI-PROJECT-15K14721
[Presentation] がん分子標的創薬を指向した低酸素誘導因子(HIF)阻害剤の探索・開発研究2014
- Author(s)
  嶋田清香、吉村彩、安田順信、高橋伸明、西村慎一、服部明、掛谷秀昭
- Organizer
  文科省新学術領域研究・がん支援「化学療法基盤支援活動」第三回シンポジウムアカデミアからの抗がん剤創薬に向けて-天然物の有効利用
- Place of Presentation
  万国津梁館(沖縄県・名護市)
- Year and Date
  2014-05-12
- Data Source
  KAKENHI-PROJECT-221S0001
[Presentation] Chemical biology for drug discovery and target identification2014
- Author(s)
  掛谷秀昭
- Organizer
  IUPAC2014 & 248th ACS National Meeting
- Place of Presentation
  San Francisco, U.S.A.
- Year and Date
  2014-08-10
- Invited
- Data Source
  KAKENHI-PROJECT-221S0001
[Presentation] "ものとり"・"ものづくり"を基盤としたケミカルバイオロジー研究2012
- Author(s)
  掛谷秀昭
- Organizer
  日本農芸化学会2011年度大会シンポジウム「食品機能学と薬理学:接点と相違点から学ぶ次のアプローチ」
- Place of Presentation
  京都(招待講演)
- Year and Date
  2012-03-25
- Data Source
  KAKENHI-PROJECT-221S0001
[Presentation] 天然物化学を基盤とした創薬ケミカルバイオロジー2012
- Author(s)
  掛谷秀昭
- Organizer
  若手研究者のための有機化学札幌セミナー
- Place of Presentation
  北海道
- Year and Date
  2012-11-26
- Data Source
  KAKENHI-PROJECT-221S0001
[Presentation] 低酸素誘導因子(HIF)の機能制御物質の探索・評価2011
- Author(s)
  掛谷秀昭
- Organizer
  シンポジウムがん支援活動「化学療法基盤支援活動」-アカデミアからの抗がん剤創薬へ向けて
- Place of Presentation
  京都(招待講演)
- Year and Date
  2011-03-09
- Data Source
  KAKENHI-PROJECT-221S0001
[Presentation] 微生物代謝産物由来の新規バイオプローブの探索とケミカルバイオロジー研究2008
- Author(s)
  掛谷秀昭、長田裕之
- Organizer
  第4回ケミカルバイオロジーシンポジウム-化学-生物融合領域創成の軌跡-
- Place of Presentation
  静岡
- Year and Date
  2008-02-07
- Data Source
  KAKENHI-PROJECT-16073223
[Presentation] "ものとり"を基盤としたケミカルバイオロジー研究.第128回日本薬学会シンポジウム天然物パワー:『ものとり,合成,機能解明』〜大学発天然物薬学研究〜2008
- Author(s)
  掛谷秀昭
- Organizer
  日本薬学会第128回年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-16073223
[Presentation] 微生物潜在能力の再認識-創薬と基礎研究への応用2008
- Author(s)
  掛谷秀昭, 他
- Organizer
  第17回天然薬物の開発と応用シンポジウム
- Place of Presentation
  九州大学(福岡)
- Data Source
  KAKENHI-PROJECT-17GS0221
[Presentation] Panepophenatnrinの不斉全合成及びその構造活性相関研究2007
- Author(s)
  掛谷秀昭, 松澤正芳, 山口潤一郎, 庄司満, 掛谷秀昭, 小野瀬利恵, 長田裕之
- Organizer
  第49回天然有機化合物討論会
- Place of Presentation
  札幌
- Year and Date
  2007-09-20
- Data Source
  KAKENHI-PROJECT-16073223
[Presentation] Epoxyquinol B inhibits the NF-kB signaltransduction pathway through the TAK1 activity.2007
- Author(s)
  神山洋, 掛谷秀昭, 臼井健郎, 櫻井宏明, 長田裕之
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-16073223
[Presentation] 有用天然有機化合物の開拓とケミカルバイオロジー研究2007
- Author(s)
  掛谷秀昭
- Organizer
  有機合成化学協会講習会(平成19年度後期(秋))
- Place of Presentation
  東京
- Year and Date
  2007-11-22
- Data Source
  KAKENHI-PROJECT-16073223
[Presentation] Aspergillus fumigatusの生産する細胞周期阻害剤トリプロスタチンの生合成遺伝子クラスターの同定2007
- Author(s)
  加藤直樹、高木海、浅見行弘、掛谷秀昭、長田裕之
- Organizer
  第2回日本ケミカルバイオロジー研究会
- Place of Presentation
  京都
- Year and Date
  2007-05-10
- Data Source
  KAKENHI-PROJECT-16073223
[Presentation] HTLV-I感染細胞および上皮系腫瘍細胞においてユビキチン化修飾酵素A20はcaspase-8抑制因子として機能する
- Author(s)
  斉藤愛記、持田佳奈子、鶴山惠理、市川裕菜、大友悠太郎、掛谷綾香、深澤麻純、宇野雅哉、徳永文稔、宇都宮與、渡邉俊樹、山岡昇司
- Organizer
  新学術領域研究「修飾シグナル病」若手ワークショップ
- Place of Presentation
  ホテルあかね(神奈川県・足柄下郡湯河原町)
- Year and Date
  2014-09-30 – 2014-10-02
- Data Source
  KAKENHI-PROJECT-221S0001

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164. 花島慎弥

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
165. 服部明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
166. 渡辺能行

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
167. 渡辺俊樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kakeya Hideaki 掛谷 秀昭

KAKEYA Hideaki 掛谷 秀昭

掛合 秀昭 カケヤ ヒデアキ

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Chemical biology on a bioactive substance regulating the hypoxia response signalPrincipal InvestigatorOngoing

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Frontier research of chemical communicationsArea Organizer

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Frontiers in Chemical CommunicationsPrincipal InvestigatorOngoing

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Biosynthetic research on cryptic gene activationPrincipal Investigator

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Chemical communications in microbial interactions and development of useful bioactive ligandsPrincipal InvestigatorOngoing

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Chemical biology on cryptic genes activationPrincipal Investigator

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微生物代謝産物由来の機能性天然分子の探索・創製と応用研究Principal Investigator

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細胞死を制御する天然有機化合物の化学生物学的解析Principal Investigator

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Kakeya Hideaki 掛谷秀昭

KAKEYA Hideaki 掛谷秀昭

掛合秀昭カケヤヒデアキ

[Book] 1. 薬の基礎知識 & 2. 創薬の世界, Newton 別冊「くすりの科学知識：くすりのしくみと、奥深き創薬の世界」2017

[Book] 1. 薬の基礎知識 & 2. 創薬の世界, Newton 別冊「くすりの科学知識：くすりのしくみと、奥深き創薬の世界」2017

[Book] 特集・制がん剤の分子標的スクリーニング成績「化学療法基盤情報支援班」報告‐制がん候補物質のスクリーニング成績・第15報『癌と化学療法オンライン』2013

[Book] 特集・制がん剤の分子標的スクリーニング成績化学療法基盤支援活動報告-制がん候補物質のスクリーニング成績・第15報2013