YOKOMIZO Akira 横溝晃

Researcher Number	60346781
Other IDs
Affiliation (based on the past Project Information) *help	2015: 九州大学, 医学(系)研究科(研究院), 准教授 2015: 九州大学, 医学研究院, 准教授 2015: 九州大学, 大学院医学研究院, 准教授 2012 – 2013: 九州大学, 医学(系)研究科(研究院), 准教授 2012: 九州大学, 大学院・医学研究院, 准教授 … More 2011: 九州大学, 医学研究院, 准教授 2010: 九州大学, 大学病院, 講師 2003 – 2006: Kyushu University hospital, Department of Urology, Stuff Doctor, 大学病院, 助手 2004: Kyushu University, Kyushu University Hospital, Research Associate, 病院・助手 2002: 九州大学, 医学部付属病院, 助手 Less
Review Section/Research Field	Principal Investigator Urology Except Principal Investigator Urology / Urology
Keywords	Principal Investigator 前立腺癌 / genome / polymorphism / prostate cancer / ゲノム / 遺伝子多型 / 分子生物学 / 化学予防 / アンドログン受容体 / 去勢治療 / 去勢抵抗性 / 酸化ストレス / アンドロゲン受容体 … More Except Principal Investigator … More IP_3R1 / bladder cancer / drug resistance / urogenital cancer / MDR1 / 膀胱癌 / マイクロアレイ / 薬剤耐性 / 尿路性器癌 / microarray / MRP / IP3R1 / cisplatin / シスプラチン / 抗癌剤 / 耐性克服 / がん分子標的薬剤 / ATL発症リスク / ATL発がん機序 / がん化学予防 / 分子疫学コーホート研究 / ATL発症予防 / 国際交流 / 個別化がん予防 / ゲノム・エピゲノム解析支援 / アカデミア創薬 / 次世代分子解析技術 / ゲノムコーホート研究 / 病理形態学 / 遺伝子改変マウス / 国際研究者交流 / 若手支援 / renal cancer / prostate cancer / genetic polymorphism / apoptosis / インターフェロン / 腎細胞癌 / DNAメチル化 / 腎癌 / 前立腺癌 / 遺伝子多型 / アポトーシス / 耐性遺伝子 / 抗癌剤耐性 / anti-cancer drug / cDNA Microarrays / overcoming of resistance / アドリアマイシン / MRP3 / MRP2 / MRP1 / 抗がん剤耐性 / 膀胱腫瘍 Less

The molecular mechanism of prostate cancer chemo-prevention agents with androgen receptor.Principal Investigator
- Principal Investigator
  
  Akira Yokomizo
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Kyushu University
The identification of molecular mechanisms of androgen receptor regulation and novel therapeutic target in prostate cancerPrincipal Investigator
- Principal Investigator
  
  YOKOMIZO Akira
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Kyushu University
Scientific Support Programs for Cancer Research Grant-in-Aid for Scientific Research on Innovative Areas
- Principal Investigator
  
  IMAI Kohzoh, 中村祐輔
- Project Period (FY)
  2010 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  The University of Tokyo
The identification of genes related to the sensitivity against anti-cancer drug, and application for clinical treatment
- Principal Investigator
  
  NAITO Seiji
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  Kyushu University
The identification of prostate cancer susceptible gene by whole genome search and candidate gene approachPrincipal Investigator
- Principal Investigator
  
  YOKOMIZO Akira
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Kyushu University
Identification of Drug Resistance Gene by Microarray and Elucidation of Mechanism of Drug Resistance in Urogenital Cancer
- Principal Investigator
  
  KOGA Hirofumi
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Kyushu University
The identification of genes related to the sensitivity against anti-cancer drug, and application for clinical treatment
- Principal Investigator
  
  NAITO Seiji
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  Kyushu University

All 2016 2015 2014 2013 2012 2011 2010 2007 2006 2005 2004

All Journal Article Presentation Book

[Book] Oxidative stress and prostate cancer2015
- Author(s)
  Shiota M, Yokomizo A, Naito S
- Total Pages
  308
- Publisher
  Elsevier
- Data Source
  KAKENHI-PROJECT-221S0001
[Book] Cancer, oxidative stress and dietary antioxidants2014
- Author(s)
  Shiota M., YokomizoA., Naito S.
- Total Pages
  283
- Publisher
  Elsevier Inc.
- Data Source
  KAKENHI-PROJECT-25462484
[Book] 酸化ストレスを標的とした治療開発2014
- Author(s)
  塩田真己、横溝晃、内藤誠二
- Publisher
  日本臨牀
- Data Source
  KAKENHI-PROJECT-221S0001
[Journal Article] The prognostic impact of serum testosterone during androgen-deprivation therapy in patients with metastatic prostate cancer and the SRD5A2 polymorphism.2016
- Author(s)
  Shiota M, Fujimoto N, Yokomizo A, Takeuchi A, Kashiwagi E, Dejima T, Kiyoshima K, Inokuchi J, Tatsugami K, Eto M.
- Journal Title
  
  Prostate Cancer Prostatic Dis.
  
  Volume: in press Issue: 2 Pages: 191-196
- DOI
  10.1038/pcan.2016.2
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25462484
[Journal Article] Equol inhibits prostate cancer growth via degradation of the androgen receptor by Skp2.2016
- Author(s)
  Itsumi M, Shiota M, Takeuchi A, Kashiwagi E, Inokuchi J, Tatsugami K, Kajioka S, Uchiumi T, Naito S, Eto M, Yokomizo A.
- Journal Title
  
  Cancer Sci
  
  Volume: in press Pages: 327-331
- DOI
  10.1016/j.intimp.2016.03.007
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462484, KAKENHI-PROJECT-26861274, KAKENHI-PLANNED-16H06496, KAKENHI-PROJECT-26293098, KAKENHI-PROJECT-26293353
[Journal Article] Aldehyde dehydrogenase 2 (ALDH2) and alcohol dehydrogenase 1B (ADH1B) polymorphisms exacerbate bladder cancer risk associated with alcohol drinking: Gene-environment interaction.2016
- Author(s)
  Masaoka H, Ito H, Soga N, Hosono S, Oze I, Watanabe M, Tanaka H, Yokomizo A, Hayashi N, Eto M, Matsuo K.
- Journal Title
  
  Carcinogenesis
  
  Volume: in press Issue: 6 Pages: 583-585
- DOI
  10.1093/carcin/bgw033
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-26253041
[Journal Article] Potential Role for YB-1 in Castration-Resistant Prostate Cancer and Resistance to Enzalutamide Through the Androgen Receptor V7.2016
- Author(s)
  Shiota M, Fujimoto N, Imada K, Yokomizo A, Itsumi M, Takeuchi A, Kuruma H, Inokuchi J, Tatsugami K, Uchiumi T, Oda Y, Naito S.
- Journal Title
  
  J Natl Cancer Inst.
  
  Volume: 108 Issue: 7 Pages: djw005-djw005
- DOI
  10.1093/jnci/djw005
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25462484, KAKENHI-PROJECT-15K20095
[Journal Article] The oncological outcome and validation of Japan Cancer of the Prostate Risk Assessment score among men treated with primary androgen-deprivation therapy2015
- Author(s)
  Shiota, M., Yokomizo A., Takeuchi A., Imada K., Kiyoshima K., Inokuchi J., Tatsugami K. and Naito S.
- Journal Title
  
  J Cancer Res Clin Oncol
  
  Volume: 141 Issue: 3 Pages: 495-503
- DOI
  10.1007/s00432-014-1828-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-221S0001
[Journal Article] SRD5A gene polymorphism in Japanese men predicts prognosis of metastatic prostate cancer with androgen-deprivation therapy.2015
- Author(s)
  Shiota M, Fujimoto N, Yokomizo A, Takeuchi A, Itsumi M, Inokuchi J, Tatsugami K, Uchiumi T, Naito S.
- Journal Title
  
  Eur J Cancer
  
  Volume: 51 Issue: 14 Pages: 1962-9
- DOI
  10.1016/j.ejca.2015.06.122
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25462484, KAKENHI-PROJECT-26861273
[Journal Article] The feature of metabolic syndrome is a risk factor for biochemical recurrence after radical prostatectomy2014
- Author(s)
  Shiota, M., Yokomizo A., Takeuchi A., Imada K., Kiyoshima K., Inokuchi J., Tatsugami K. and Naito S.
- Journal Title
  
  J Surg Oncol
  
  Volume: 110 Issue: 4 Pages: 476-481
- DOI
  10.1002/jso.23677
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-221S0001
[Journal Article] Risk factors for febrile neutropenia in patients receiving docetaxel chemotherapy for castration-resistant prostate cancer2014
- Author(s)
  Shiota, M., Yokomizo A., Takeuchi A., Imada K., Kiyoshima K., Inokuchi J., Tatsugami K. and Naito S.
- Journal Title
  
  Support Care Cancer
  
  Volume: 22 Issue: 12 Pages: 3219-3226
- DOI
  10.1007/s00520-014-2328-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-221S0001
[Journal Article] The oncological outcomes and risk stratification in docetaxel chemotherapy for castration-resistant prostate cancer2014
- Author(s)
  Shiota, M., Yokomizo A., Adachi T., Koga H., Yamaguchi A., Imada K., Takeuchi A., Kiyoshima K., Inokuchi J., Tatsugami K. and Naito S.
- Journal Title
  
  Jpn J Clin Oncol
  
  Volume: 44 Issue: 9 Pages: 860-867
- DOI
  10.1093/jjco/hyu081
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-221S0001
[Journal Article] EP2 signaling mediates suppressive effects of celecoxib on androgen receptor expression and cell proliferation in prostate cancer2014
- Author(s)
  Kashiwagi E, Shiota M, *Yokomizo A, Inokuchi J, Uchiumi T, Naito S.
- Journal Title
  
  Prostate Cancer P D
  
  Volume: 17 Issue: 1 Pages: 10-17
- DOI
  10.1038/pcan.2013.53
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24590387, KAKENHI-PROJECT-25253041, KAKENHI-PROJECT-25462484, KAKENHI-PROJECT-221S0001
[Journal Article] Prostaglandin receptor EP3 mediates growth inhibitory effect of aspirin through androgen receptor and contributes to castration resistance in prostate cancer cells.2013
- Author(s)
  Kashiwagi E, Shiota M, Yokomizo A, Itsumi M, Inokuchi J, Uchiumi T, Naito S.
- Journal Title
  
  Endocr Relat Cancer
  
  Volume: 20 Issue: 3 Pages: 431-441
- DOI
  10.1530/erc-12-0344
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462484
[Journal Article] Statins reduce the androgen sensitivity and cell proliferation by decreasing the androgen receptor protein in prostate cancer cells2011
- Author(s)
  Yokomizo A., et al
- Journal Title
  
  Prostate
  
  Volume: 15 Issue: 3 Pages: 298-304
- DOI
  10.1002/pros.21243
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591769
[Journal Article] Statins reduce the androgen sensitivity and cell proliferation by decreasing the androgen receptor protein in prostate cancer cells.2010
- Author(s)
  Yokomizo A
- Journal Title
  
  Prostate
  
  Volume: 15 Pages: 298-304
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591769
[Journal Article] The association analysis of Glutathion S-Transferase P1 Polymorphism with urothelial cancer susceptibility and myelosuppression after M-VAC chemotherapy.2007
- Author(s)
  Yokomizo A. et al.
- Journal Title
  
  Int. J. Urol (In press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390466
[Journal Article] The association analysis of Glutathion S-Transferase P1 Polymorphism with urothelial cancer susceptibility and myelosuppression after M-VAC chemotherapy.2007
- Author(s)
  Yokomizo A, Yamamoto K, Kinukawa N, Tsunoda T, Koga H, Naito S.
- Journal Title
  
  Int.J.Urol. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591600
[Journal Article] The association analysis of Glutathion S-Transferase P1 Polymorphism with urothelial cancer susceptibility and myelosuppression after M-VAC chemotherapy.2007
- Author(s)
  Yokomizo A
- Journal Title
  
  Int.J.Urol. (In press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591600
[Journal Article] Percentage of positive biopsy cores, preoperative prostate-specific antigen (PSA) level, pT and Gleason score as predictors of PSA recurrence after radical prostatectomy : a multi-institutional outcome study in Japan.2006
- Author(s)
  Yokomizo A
- Journal Title
  
  BJU Int. 98
  
  Pages: 549-553
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591600
[Journal Article] Percentage of positive biopsy cores, preoperative prostate-specific antigen (PSA) level, pT and Gleason score as predictors of PSA recurrence after radical prostatectomy : a multi-institutional outcome study in Japan.2006
- Author(s)
  Yokomizo A, Murai M, Baba S, Osamu Ogawa O, Tsukamoto T, Niwakawa M, Tobisu K, Kinukawa N, Naito S
- Journal Title
  
  BJU Int. 98
  
  Pages: 549-553
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591600
[Journal Article] Randomized Controlled Trial to Evaluate Radiation plus Endocrine Therapy or Endocrine Therapy alone for PSA failure after radical prostatectomy.2005
- Author(s)
  Yokomizo A
- Journal Title
  
  Jpn.J.Clin.Oncol 35
  
  Pages: 34-36
- Data Source
  KAKENHI-PROJECT-16591600
[Journal Article] Association of HER-2 Polymorphism with Japanese Sporadic Prostate Cancer Susceptibility.2005
- Author(s)
  Yokomizo A, Koga H, Kinukawa N, Tsukamoto T, Hirao Y, Akaza H, Mori M, Naito S.
- Journal Title
  
  Prostate 62
  
  Pages: 49-53
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591600
[Journal Article] Association of HER-2 Polymorphism with Japanese Sporadic Prostate Cancer Susceptibility2005
- Author(s)
  Yokomizo A
- Journal Title
  
  Prostate 62
  
  Pages: 49-53
- Data Source
  KAKENHI-PROJECT-16591600
[Journal Article] Association of HER-2 polymorphism with Japanese sporadic prostate cancer susceptibility.2005
- Author(s)
  Yokomizo, A ら
- Journal Title
  
  Prostate 62
  
  Pages: 49-53
- Data Source
  KAKENHI-PROJECT-16390466
[Journal Article] Randomized Controlled Trial to Evaluate Radiation plus Endocrine Therapy or Endocrine Therapy alone for PSA failure after radical prostatectomy : Japan Clinical Oncology Group Study JCOG 0401.2005
- Author(s)
  Yokomizo A, Tobisu K, Kawamoto H, Nihei K, Ishizuka N, Naito S.
- Journal Title
  
  Jpn.J.Clin.Oncol. 35
  
  Pages: 34-36
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591600
[Journal Article] Inositol 1,4,5-triphosphate (IP3) receptor type 1(IP3R1) modulates the acquisition of cisplatin resistance in bladder cancer cell lines.2005
- Author(s)
  Tsunoda T, Koga H, Yokomizo A, Tatsugami K, Eto M, Inokuchi J, Hirata A, Okumura K, Naito S
- Journal Title
  
  Oncogene 24(8)
  
  Pages: 1396-1402
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571506
[Journal Article] Association of HER-2 polymorphism with Japanese sporadic prostate cancer susceptibility.2005
- Author(s)
  Yokomizo A
- Journal Title
  
  Prostate 62・1
  
  Pages: 49-53
- Data Source
  KAKENHI-PROJECT-16390466
[Journal Article] 前立腺癌における疾病感受性遺伝子HER2とHPC2の多型解析2005
- Author(s)
  横溝晃
- Journal Title
  
  日本腎泌尿器疾患予防医学研究会誌 12
  
  Pages: 13-15
- NAID
  110003071632
- Data Source
  KAKENHI-PROJECT-16591600
[Journal Article] Association of HER-2 polymorphism with Japanese sporadic prostate cancer Susceptibility.2005
- Author(s)
  Yokomizo A, et al.
- Journal Title
  
  Prostate 62(1)
  
  Pages: 49-53
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390466
[Journal Article] Inositol 1,4,5-trisphosphate (IP(3)) receptor type1 (IP(3)R1) modulates the acquisition of cisplatin resistance in bladder cancer cell lines.2005
- Author(s)
  Tsunoda T, Koga H, Yokomizo A, Tatsugami K, Eto M, Inokuchi J, Hirata A, Masuda K, Okumura K, Naito S.
- Journal Title
  
  Oncogene 24
  
  Pages: 1396-402
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591600
[Journal Article] HPC2/ELAC2 polymorphism associated with Japanese sporadic prostate cancer.2004
- Author(s)
  Yokomizo A, et al.
- Journal Title
  
  Prostate 61(3)
  
  Pages: 248-252
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390466
[Journal Article] Anatomical features of periprostatic tissue and its surroundings : a histological analysis of 79 radical retropubic prostatectomy specimens.2004
- Author(s)
  Kiyoshima K, Yokomizo A, Yoshida T, Tomita K, Yonemasu H, Nakamura M, Oda Y, Naito S, Hasegawa Y.
- Journal Title
  
  Jpn.J.Clin.Oncol. 34
  
  Pages: 463-468
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591600
[Journal Article] HPC2/ELAC2 Polymorphism Associated with Japanese Sporadic Prostate Cancer.2004
- Author(s)
  Yokomizo A, Koga H, Kinukawa N, Tsukamoto T, Hirao Y, Akaza H, Mori M, Naito S.
- Journal Title
  
  Prostate 61
  
  Pages: 248-252
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591600
[Journal Article] 前立腺癌における疾病感受性遺伝子HER2とHPC2の多型解析2004
- Author(s)
  横溝晃
- Journal Title
  
  日本腎泌尿器疾患予防医学研究会誌 12
  
  Pages: 13-15
- NAID
  110003071632
- Data Source
  KAKENHI-PROJECT-16390466
[Journal Article] HPC2/ELAC2 polymorphism associated with Japanese sporadic postate cancer.2004
- Author(s)
  Yokomizo A
- Journal Title
  
  Prostate 61・3
  
  Pages: 248-252
- Data Source
  KAKENHI-PROJECT-16390466
[Journal Article] Gluthatione-S-transferase P1 polymorphism 1105V in familial and sporadic prostate cancer.2004
- Author(s)
  Debes JD, Yokomizo A, McDonnell SK, Hebbring SJ, Christensen GB, Cunningham JM, Jacobsen SJ, Tindall DJ, Liu W, Schaid DJ, Thibodeau SN.
- Journal Title
  
  Cancer Genet Cytogenet. 155
  
  Pages: 82-86
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591600
[Journal Article] Alteration in copy numbers of genes as a mechanism for acquired drug resistance.2004
- Author(s)
  Yasui K, Mihara S, Zhao C, Okamoto H, Saito-Ohara F, Tomida A, Funato T, Yokomizo A, Naito S, Imoto I, Tsuruo T, Inazawa J.
- Journal Title
  
  Cancer Res. 64
  
  Pages: 1403-10
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591600
[Journal Article] HPC2/ELAC2 Polymorphism Associated with Japanese Sporadic Prostate Cancer2004
- Author(s)
  Yokomizo A
- Journal Title
  
  Prostate 61
  
  Pages: 248-252
- Data Source
  KAKENHI-PROJECT-16591600
[Presentation] Equol promotes protein degradation of androgen receptor via Skp2 and suppressed cell proliferation in prostate cancer2015
- Author(s)
  Mmoe Itsumi, Masaki Shiota, Akira Yokomizo, Eiji Kashiwagi, Aro Takeuchi, Kenjiro Imada, Katsunori Tatsugami, Junichi Inokuchi, Takeshi Uchiumi, Shunichi Kajioka, Seiji Naito
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-10-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462484
[Presentation] Isoflavons, daidzein and equol, are involved in the biology of prostate cancer2014
- Author(s)
  Momoe Itsumi, Masaki Shiota, Akira Yokomizo, Eiji Kashiwagi, Ario Takeuchi, Keijiro Imada, Katsunori Tatsugami, Junichi Inokuchi, Takeshi Uchiumi, Seiji Naito
- Organizer
  The 4th Asian Pacific Prostate Society in Okinawa
- Place of Presentation
  沖縄県　ブセナテラス
- Data Source
  KAKENHI-PROJECT-25462484
[Presentation] peroxiredoxin 2は、前立腺癌においてアンドロゲン受容体の活性を制御している2013
- Author(s)
  塩田真己、横溝　晃他
- Organizer
  泌尿器分子細胞研究会
- Place of Presentation
  高知
- Data Source
  KAKENHI-PROJECT-22591769
[Presentation] 前立腺癌治療抵抗性獲得機序の解明とその克服法の研究2012
- Author(s)
  塩田真己、横溝晃、宋裕賢、武内在雄、柏木英志、内藤誠二
- Organizer
  前立腺シンポジウム
- Data Source
  KAKENHI-PROJECT-22591769
[Presentation] 前立腺癌治療抵抗性獲得機序の解明とその克服法の研究2012
- Author(s)
  塩田真己、横溝　晃他
- Organizer
  前立腺シンポジウム
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-22591769
[Presentation] Peroxiredoxin 2 in nucleus and cytoplasm distinctly regulates androgen receptor activity in prostate cancer cells2012
- Author(s)
  Yokomizo A, Shiota M, Kashiwagi E, Takeuchi A, Fujimoto N, Uchiumi T, and Naito S
- Organizer
  ANNUAL EUROPEAN UROLOGICAL ASSOCIATION CONGRESS
- Data Source
  KAKENHI-PROJECT-22591769
[Presentation] Peroxisome Proliferator-Activated Receptor Coactivator-1 Interacts with the Androgen Receptor (AR) and Promotes Prostate Cancer Cell Growth by activating the AR2011
- Author(s)
  Yokomizo A., et al
- Organizer
  American Urological Association Annual meeting 2011
- Place of Presentation
  米国ワシントンDC
- Year and Date
  2011-05-15
- Data Source
  KAKENHI-PROJECT-22591769
[Presentation] Statins Reduce the Androgen Sensitivity and Cell Proliferation by Decreasing the Androgen Receptor Protein in Prostate Cancer Cells2011
- Author(s)
  Yokomizo A
- Organizer
  26^<th> Annual European Association of Urology Congress
- Place of Presentation
  オーストリア、ウィーン
- Year and Date
  2011-03-21
- Data Source
  KAKENHI-PROJECT-22591769
[Presentation] 前立腺癌におけるPhosphodiesterase 4BとProtein Kinase Aを介した去勢抵抗性の獲得機序2011
- Author(s)
  柏木英志、横溝晃、塩田真己、田中慎吾、猪口淳一、内藤誠二
- Organizer
  前立腺シンポジウム
- Data Source
  KAKENHI-PROJECT-22591769
[Presentation] Peroxisome Proliferator-Activated Receptor Coactivator-1 Interacts with the Androgen Receptor (AR) and Promotes Prostate Cancer Cell Growth by activating the AR2011
- Author(s)
  Yokomizo A, Shiota M, Inokuchi J, Tatsugami K, Kuroiwa K, Fujimoto N, and Naito S
- Organizer
  ANNUAL MEETING OF AMERICAN UROLOGICAL ASSOCIATION
- Data Source
  KAKENHI-PROJECT-22591769
[Presentation] Statins Reduce the Androgen Sensitivity and Cell Proliferation by Decreasing the Androgen Receptor Protein in Prostate Cancer Cells2011
- Author(s)
  Yokomizo A, Shiota M, Kashiwagi E, Kuroiwa K, Tatsugami K, Inokuchi J, Takeuchi A, Naito S
- Organizer
  ANNUAL EUROPEAN UROLOGICAL ASSOCIATION CONGRESS
- Data Source
  KAKENHI-PROJECT-22591769
[Presentation] 前立腺癌におけるPhosphodiesterase 4BとProtein Kinase Aを介した去勢抵抗性の獲得機序2011
- Author(s)
  柏木英志, 横溝晃, 他
- Organizer
  前立腺シンポジウム
- Place of Presentation
  東京コンファレンスセンター(招待講演)
- Year and Date
  2011-12-10
- Data Source
  KAKENHI-PROJECT-22591769
[Presentation] スタチンによる前立腺癌のアンドロゲン受容体発現低下と増殖抑制効果2010
- Author(s)
  横溝晃
- Organizer
  前立腺シンポジウム
- Place of Presentation
  東京コンファレンスセンター
- Year and Date
  2010-12-11
- Data Source
  KAKENHI-PROJECT-22591769
[Presentation] The castration-induced oxidativestress makes prostate cancer cells castration resistant through Twist1 and androgen receptor overexpression2010
- Author(s)
  Yokomizo A, Shiota M, Tada Y, Inokuchi J, Masubuchi D, Eto M, Naito S
- Organizer
  ANNUAL MEETING OF AMERICAN UROLOGICAL ASSOCIATION
- Data Source
  KAKENHI-PROJECT-22591769
[Presentation] Statins Reduce the Androgen Sensitivity and Cell Proliferation by Decreasing the Androgen Receptor Protein in Prostate Cancer Cells2010
- Author(s)
  Yokomizo A, Shiota M, Eiji Kashiwagi, Kuroiwa K, Tatsugami K, Inokuchi J, Takeuchi A, Naito S
- Organizer
  SIXTH INTERNATIONAL SYMPOSIUM ON HORMONAL ONCOGENESIS
- Data Source
  KAKENHI-PROJECT-22591769

1. NAITO Seiji (40164107)

# of Collaborated Projects: 5 results

# of Collaborated Products: 15 results
2. KOGA Hirofumi (20271108)

# of Collaborated Projects: 4 results

# of Collaborated Products: 5 results
3. OKUMURA Koji (40325519)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. 多田靖弘 (00403999)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. TSUNODA Toshiyuki

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
6. 猪口淳一

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. KUROIWA Kentaro (90403964)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. SHIOTA Masaki (20635445)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
9. ETO Masatoshi (90315078)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. TATSUGAMI Katsunori (90380617)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. SASAZUKI Takehiko (50014121)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. INOKO Hidetoshi (10101932)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. YAMAMOTO Ken (60274528)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. IMAI Kohzoh (60117603)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. INOUE Junichiro (70176428)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. NAKAMURA Takuro (00180373)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. ISHIKAWA Fuyuki (30184493)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. YAMAMURA Kenichi (90115197)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. ARAKI Kimi (90211705)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. YAO Ryouji (80291095)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. TAKANO Hiroshi (00241555)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. TAKAKURA Akira (60167484)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. KATOH Hideki (30142053)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. NAKAGATA Naomi (30159058)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. TOYOKUNI Shinya (90252460)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. WANIBUCHI Hideki (90220970)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. OGAWA Katsuhiro (50045514)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. MITSUMORI Kunitoshi (10239296)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. YAMADA Yasuhiro (70313872)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. SHIBUTANI Makoto (20311392)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. IMAIDA Katsumi (90160043)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. FUTAKUCHI Mitsuru (60275120)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. KANDA Hiroaki (90260067)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. TANAKA Hideo (60470168)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
35. WAKAI Kenji (50270989)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. MIKAMI Haruo (10332355)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. SUZUKI Sadao (20226509)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. MIURA Katsuyuki (90257452)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. WATANABE Yoshiyuki (00191809)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. ARISAWA Kokichi (30203384)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
41. TANAKA Keitaro (50217022)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
42. TAKEZAKI Toshiro (50227013)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
43. FURUSHO Norihiro (10346786)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
44. NAITO Mariko (10378010)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
45. OHNAKA Keizo (30325518)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
46. KITA Yoshikuni (30147524)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
47. KURIKI Kiyonori (20543705)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
48. TAMAKAOSHI Akiko (90236737)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
49. EGUCHI Hidetaka (00260232)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
50. KUBO Michiaki (30442958)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
51. HAMAJIMA Nobuyuki (30172969)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
52. NAGATA Chisato (30283295)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
53. HINO Okio (90127910)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
54. TAHARA Hidetoshi (00271065)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
55. SUGIMURA Haruhiko (00196742)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
56. TSUGANE Shoichiro (40179982)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
57. NAKATOCHI Masahiro (10559983)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
58. TAKAYAMA Tetsuji (10284994)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
59. AKAZA Hideyuki (70010486)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
60. TAKAHASHI Satoru (50197141)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
61. TSUKAMOTO Taiji (50112454)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
62. MASUMORI Naoya (20295356)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
63. NAMIKI Mikio (70155985)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
64. FUJIMOTO Kiyohide (50264867)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
65. FUJIOKA Tomoaki (80173409)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
66. HORIE Shigeo (40190243)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
67. MORI Mitsuru (50175634)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
68. MORIWAKI Hisataka (50174470)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
69. Shimizu Masahito (90402198)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
70. KANNAGI Mari (80202034)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
71. ISHIDA Takashi (80405183)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
72. MATSUOKA Masao (10244138)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
73. YAMAOKA Shoji (90263160)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
74. TANAKA Yuetsu (30163588)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
75. WATANABE Toshiki (30182934)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
76. YASUI Hiroshi (40448593)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
77. TSUCHIYA Eiju (00072314)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
78. DAIGO Yataro (30345029)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
79. MIYAGI Yohei (00254194)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
80. TAKAHASHI Takashi (50231395)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
81. YAMORI Takao (60200854)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
82. SEIMIYA Hiroyuki (50280623)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
83. UEHARA Yoshimasa (50160213)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
84. YOSHIDA Minoru (80191617)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
85. IMOTO Masaya (60213253)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
86. FUKAZAWA Hidesuke (10218878)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
87. KAKEYA Hideaki (00270596)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
88. DAN Shingo (70332202)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
89. TOMIDA Akihiro (40251483)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
90. KAWADA Manabu (20300808)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
91. OSADA Hiroyuki (80160836)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
92. MATSUURA Masaaki (40173794)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
93. MIZUKAMI Tamio (80367896)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
94. MASHIMA Tetsuo (30311228)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
95. USHIJIMA Masaru (60328565)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
96. TOKINO Takashi (40202197)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
97. SUZUKI Hiromu (20381254)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
98. SHINOMURA Yasuhisa (90162619)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
99. NOSHO Katsuhiko (10597339)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
100. MIYAZONO Kohei (90209908)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
101. INAZAWA Johji (30193551)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
102. HIROTA Toru (50421368)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
103. NODA Tetsuo (10183550)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
104. SUZUKI Misao (60253720)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
105. TAKEDA Naoki (90304998)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
106. YAGINUMA Katsuyuki (40182307)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
107. SUGITANI Yoshinobu (80360569)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
108. ITO Hidemi (90393123)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
109. HOSONO Satoyo (80402600)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
110. IWASAKI Motoki (60392338)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
111. NAGASE Hiroki (90322073)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
112. NISHITA Hiroki (40531257)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
113. KONO Suminori (70128015)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
114. HASHIMOTO Syuji (50148334)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
115. YAMAGUCHI Kazunari (20128325)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
116. TAKANO Atsushi (50582607)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
117. TERAMOTO Koji (10452244)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
118. MATSUDA Koichi (90401257)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
119. TANAKA Yukichi (50420691)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
120. AOKI Ichiro (00184028)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
121. OSAMURA Yoshiyuki (10100992)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
122. NAKAMURA Naoya (50227922)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
123. SUZUKI Noboru (40235982)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
124. TAJIRI Michihiko (00449117)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
125. KAWASAKI Takashi (20377188)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
126. YOKOSE Tomoyuki (10221665)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
127. YANAGISAWA Kiyoshi (20372112)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
128. HIRAKAWA Akihiro (90609330)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
129. IIJIMA Yoshihiko (50584679)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
130. ZEMBUTSU Hitoshi (90372820)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
131. SASAKI Yasushi (70322328)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
132. IDOGAWA Masashi (00404749)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
133. MARUYAMA Reo (60607985)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
134. KAI Masahiro (80260777)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
135. 後藤健 (70325447)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
136. 中村祐輔 (70217909)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
137. 平田晃

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
138. 渡辺能行

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
139. 渡辺俊樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
140. 内海健

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

YOKOMIZO Akira 横溝 晃

Research Projects

Research Products

Co-Researchers

The molecular mechanism of prostate cancer chemo-prevention agents with androgen receptor.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The identification of molecular mechanisms of androgen receptor regulation and novel therapeutic target in prostate cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Scientific Support Programs for Cancer Research Grant-in-Aid for Scientific Research on Innovative Areas

Principal Investigator

Project Period (FY)

Research Category

Research Institution

The identification of genes related to the sensitivity against anti-cancer drug, and application for clinical treatment

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The identification of prostate cancer susceptible gene by whole genome search and candidate gene approachPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of Drug Resistance Gene by Microarray and Elucidation of Mechanism of Drug Resistance in Urogenital Cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The identification of genes related to the sensitivity against anti-cancer drug, and application for clinical treatment

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Oxidative stress and prostate cancer2015

Author(s)

Total Pages

Publisher

Data Source

[Book] Cancer, oxidative stress and dietary antioxidants2014

Author(s)

Total Pages

Publisher

Data Source

[Book] 酸化ストレスを標的とした治療開発2014

Author(s)

Publisher

Data Source

[Journal Article] The prognostic impact of serum testosterone during androgen-deprivation therapy in patients with metastatic prostate cancer and the SRD5A2 polymorphism.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Equol inhibits prostate cancer growth via degradation of the androgen receptor by Skp2.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Aldehyde dehydrogenase 2 (ALDH2) and alcohol dehydrogenase 1B (ADH1B) polymorphisms exacerbate bladder cancer risk associated with alcohol drinking: Gene-environment interaction.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Potential Role for YB-1 in Castration-Resistant Prostate Cancer and Resistance to Enzalutamide Through the Androgen Receptor V7.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The oncological outcome and validation of Japan Cancer of the Prostate Risk Assessment score among men treated with primary androgen-deprivation therapy2015

YOKOMIZO Akira 横溝晃