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KONNO Tasuke
今野 多助
Researcher Number
00004846
Affiliation
*help
1997 – 1998 : 東北大, 加齢医学研究所, 教授
1998 : Institute of Development, Aging and Cancer, Department of Pediatric Oncology Toh, 加齢医学研究所・発達病態研究分野, 前教授
1993 – 1997 : 東北大学, 加齢医学研究所, 教授
1996 : 東北大学, 加齢医学研究所, 助手
1987 – 1992 : Research Institute for Tuberculosis and Cancer, Tohoku University, 抗酸菌病研究所, 教授
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1989 : 東北大学, 抗酸菌病研所, 教授
1988 : 東北大学, 抗酸菌病 研究所, 教授
1986 : 東北大, 抗酸菌病研究所, 教授
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Research Field
Except Principal Investigator
Pediatrics
/
Immunology
/
内科学一般
Keywords
Except Principal Investigator
p47-phox / HEMATOPOIETIC STEM CELLS / IgD / GM-CSF / LFA-1 / 造血幹細胞 / BCR / アポトーシス / gp91-phox / シグナル伝達
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/ XSCID / レトロウイルスベクター / WASP / HLA不適合 / ABL / 骨髄移植 / モノクローナル抗体 / Precursor B cell line / IL-2セレプターγ鎖 / HLA-haplotype / 同権骨髄移植 / CD34 / IL-2 / acute GVHD / インテグリン / 単クローン抗体 / Integrins / X linked agammaglobulinemia / C-KIT / NK cell / JAK1,3 / K+λ産生細胞クローン / インターロイキン15 / IL-2受容体 / flow cytometry / β-アクチン / superoxide / bone marrow transplantation / T細胞除去 / ワクチン / anti-CD11a / 慢性肉芽腫症 / FEEDER CELL DEPENDENCY / IgD産生細胞株 / エレクトロポレーション / histoincompability / HLA不適合ドナ- / I cell-depleted immunodeficiency / T細胞 / Bone marrow transplantation / 小児白血病 / リンパ球芽球化反応 / シトクロム / インターロイキン2(IL-2) / LFA-1 antibody / エプスタイン・バ-ウィルス / knockout mice / graft rejection / tyrosine kinase / 末熟骨髄性白血病細胞株 / T-ALL / 抗 イディオ-イディオタイプ抗体 / 遺伝子診断 / Wiskott-Aldrich症候群 / monoclonal antibody / 細胞内アクチン異常症 / 未熟B細胞株 / beta-actin / IMMATURE MYELOYD LEUKEMIA CELL LINE / 遺伝子導入 / Wiskott-aldrich症候群 / NK細胞 / X連鎖重症複合免疫不全症 / 神経芽細胞腫 / 骨髓移植 / GMーCSF / Signal Transduction / abl / 移植片対宿主病 / ロタウィルス / γc鎖 / NK activity / 表面マーカー / T cell differntiation and growth / ELECTROPORATION / プレBリンパ芽球様細胞株 / 活性酸素 / CD_<11>a / 抗イディオタイプ抗体 / 好中球 / interleukin 2 (IL-2) / Epstein-Barr virus / 移植片拒絶 / eosinophil / ケミルミネセンス / neutrophil / gene diagnosis / IL-2 RECEPTOR gamma CHAIN / c-kit / 保因者診断 / 無ガンマグロブリン血症 / IgD producer / HLA-mismatch / マウスモノクロ-ナル抗体 / CD11 / HLA不一致 / 免疫不全症 / 赤血球凝集素 / HLA / kappa-lambda double producer / CGD / allogeneic BMT / Clonal transformation / IL-2レセプターγ鎖 / チロシンキナーゼ / Bリンパ芽球様細胞株 / GATA転写因子 / 単クロ-ン抗体 / c-Kit / リンパ球膜分化抗原 / enzyme-linked immunosrobent assay / βアクチン / 細胞株 / リーダー配列 / SOLUBLE FACTOR / T細胞分化増殖 / 細胞クローニング / マウス抗WASP単クローン抗体 / mouse monoclonal antibody / Adhesion molecule / 免疫磁気ビーズ / 支持細胞依存性 / B cell growth factor / EBウイルス / Chronic granulomatous disease / K+入鎖産生細胞クローン / HLA-nonidentical dorno / 寛容 / Cell line / インターロイキン2 (IL-2) / CD34陽性細胞 / 白血球粘着不全症 / クロ-ナル・トランスフォ-メ-ション / 先天性無ガンマグロブリン血症 / ELISA法 / retrovirus vector / エプスタイル・バン ウイルス / NK活性 / carrier detection / K-λダブルプロデュ-サ- / phagocyte / 白血球 / 伴性無ガンマグロブリン血症 / 液性因子 / interleukin-15 / 同種骨髄移植 / 未熟骨髄性白血病細胞株 / フローサイトメトリー / 細胞接着分子 / gammac chain / サイトカイン / GENE TRANSFECTION / B細胞関連抗原 / サイイトカイン / IL-2 receptor / インターフェロンα / congenital agammaglobulinemia / CD_<18> / 遺伝性疾患 / 好酸球 / エプスタイン-・バ-ウィルス / LFAー1 / mouse anti-WASP monoclonal antibody / γ鎖ノックアウトマウス / 抗LFAー1抗体 / 急性移植片対宿主病 / B細胞増殖因子 / GVHD / cytokine / HLAハプロタイプ / 酵素免疫法(ELISA) / γ鎖 / κーλ鎖2重産生株 / 粘着蛋白質 / Wiskott-Aldrich syndrome / 食細胞 / 白血病 / 高IgE症候群 / 白血病細胞株 / Neuroblastoma / CD18 / ノックアウトマウス / 組織適合成 / Fcレセプタ- / bcr
Less
Research Projects
(
15
results)
Co-Researchers
(
23
People)
Project Start Year(Newest)
Project Start Year(Oldest)
Development of a tumor vaccine using a membrane attached form of interleukin-15
Principal Investigator
Principal Investigator
MINEGISHI Masayoshi
, 今野 多助
Project Period (FY)
1997 – 1998
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Pediatrics
Research Institution
Tohoku University
Analysis of molecular mechanism of inherited phagocyte disorders.
Principal Investigator
KANEGASAKI Shiro
Project Period (FY)
1996 – 1998
Research Category
Grant-in-Aid for Scientific Research (A)
Research Field
内科学一般
Research Institution
The University of Tokyo
Function of the gene of Wiskott-Aldrich syndrome
Principal Investigator
TSUCHIYA Shigeru
Project Period (FY)
1996 – 1997
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Pediatrics
Research Institution
Tohoku University
Regulatory Factors for Growth or Apoptosis of Neuroblastoma Cells and Its Therapeutic Application
Principal Investigator
MINEGISHI Masayoshi
Project Period (FY)
1996 – 1997
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Pediatrics
Research Institution
Tohoku University
Study of mechanism of X-licombined immunodeficiency caused by mutations of the IL-2 receptor gamma chain
Principal Investigator
SUGAMURA Kazuo
Project Period (FY)
1994 – 1996
Research Category
Grant-in-Aid for Scientific Research (A)
Research Field
Immunology
Research Institution
Tohoku University
PURIFICATION OF HEMATOPOIETIC STEM CELLS BY A CD117 MONOCLONAL ANTIBODY,MTK1, IN ORDER TO TRANSFECT HUMAN GENES-A PRELIMINARY STUDY
Principal Investigator
TSUCHIYA Shigeru
Project Period (FY)
1994 – 1995
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Pediatrics
Research Institution
INSTITUTE FOR DEVELOPMENT,AGING AND CANCER (IDAC) Tohoku University
小児白血病細胞におけるGATA転写因子郡の発現に関する研究
Principal Investigator
Principal Investigator
今野 多助
Project Period (FY)
1993
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Pediatrics
Research Institution
Tohoku University
ESTABLISHMENT AND CHARACTERIZATION OF AN IMMATURE MYELOID CELL LINE, M-MOK, GROWN IN THE PRESENCE OF FIBROBLAST-FEEDER CELLS
Principal Investigator
TSUCHIYA Shigeru
Project Period (FY)
1991 – 1992
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Pediatrics
Research Institution
RESEARCH INSTITUTE FOR TUBERCULOSIS AND CANCER, TOHOKU UNIVERSITY (RITC,TU)
In vivo infusion of anti-CD11a/LFA-1 antibody for prevention and treatment of severe GVHD in HLA-nonidentical bone marrow transplantation : Its serum concentrations and biological effects.
Principal Investigator
Principal Investigator
KONNO Tasuke
Project Period (FY)
1990 – 1991
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Pediatrics
Research Institution
Tohoku University
Abnormal Immunoglobulin in a Patient with X-Linked Agammaglobulinemia
Principal Investigator
TSUCHIYA shigeru
Project Period (FY)
1989 – 1990
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Pediatrics
Research Institution
Tohoku University
CD11/CD18欠損白血球の1gGFcレセプタ-の発現異常とその病態との関連
Principal Investigator
佐藤 徹雄
Project Period (FY)
1989
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Pediatrics
Research Institution
Tohoku University
抗イデイオタイプ抗体を用いたヒトロタウィルス感染成立機序の解析
Principal Investigator
SATO Tetsuo
Project Period (FY)
1988
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Pediatrics
Research Institution
Tohoku University
Anti-human LFA-1 monoclonal antibodies for prevention of graft failure in HLA-mismatched bone marrow transplantation.
Principal Investigator
Principal Investigator
KONNO Tasuke
Project Period (FY)
1988 – 1989
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Pediatrics
Research Institution
Tohoku University
Etiology of congenital agammaglobulinemia: Growth defect of precursor B lymphoblastoid cell lines and immunoglobulin gene rearrangements.
Principal Investigator
TSUCHIYA Shigeru
Project Period (FY)
1987 – 1988
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Pediatrics
Research Institution
TOHOKU UNIVERSITY
Studies on Immunologic Reconstitution after HLA-haplotype Mismatched parental Marrow Transplantation
Principal Investigator
Principal Investigator
KONNO Tasuke
Project Period (FY)
1986 – 1987
Research Category
Grant-in-Aid for General Scientific Research (A)
Research Field
Pediatrics
Research Institution
TOHOKU UNIVERSITY
# of Projects (Dsc)
# of Projects (Asc)
1.
MASAYOSHI Minegishi
(20211592)
# of Collaborated Projects :
11results
# of Collaborated Products :
0results
2.
TSUCHIYA shigeru
(30124605)
# of Collaborated Projects :
10results
# of Collaborated Products :
0results
3.
SATO Tetsuo
(90170761)
# of Collaborated Projects :
8results
# of Collaborated Products :
0results
4.
MASAHIKO Terasawa
(80192201)
# of Collaborated Projects :
4results
# of Collaborated Products :
0results
5.
FUJIE Hiromi
(60282000)
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
6.
MINEGISHI Naoko
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
7.
SUGAMURA Kazuo
(20117360)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
8.
KASAI Noriyuki
(60001947)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
9.
ASAO Hironobu
(80250744)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
10.
OHASHI Yoshiyuki
(60250825)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
11.
KANEGASAKI Shiro
(10012767)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
12.
NUNOI Hiroyuki
(50218260)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
13.
KOMIYAMA Jun
(50020798)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
14.
KITAGAWA Seiichi
(50133278)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
15.
SENDO Fujiro
(80091833)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
16.
KOBAYASHI Kunihiko
(60091451)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
17.
大保 和之
(70250744)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
18.
竹重 公一朗
(10037450)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
19.
小林 陽之助
(50034062)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
20.
洲崎 健
(90134048)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
21.
KUMAKI Satoru
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
22.
YAMAGUTI Yosiko
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
23.
TERASAWA Masahiko
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
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