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KONNO Tasuke  今野 多助

ORCIDConnect your ORCID iD *help
Researcher Number 00004846
Affiliation (based on the past Project Information) *help 1998: Institute of Development, Aging and Cancer, Department of Pediatric Oncology Toh, 加齢医学研究所・発達病態研究分野, 前教授
1993 – 1997: 東北大学, 加齢医学研究所, 教授
1996: 東北大学, 加齢医学研究所, 助手
1987 – 1992: Research Institute for Tuberculosis and Cancer, Tohoku University, 抗酸菌病研究所, 教授
1989: 東北大学, 抗酸菌病研所, 教授
1988: 東北大学, 抗酸菌病 研究所, 教授
1986: 東北大, 抗酸菌病研究所, 教授
Review Section/Research Field
Principal Investigator
Pediatrics
Except Principal Investigator
Pediatrics / Immunology / 内科学一般
Keywords
Principal Investigator
HLA不適合 / 骨髄移植 / LFA-1 / 小児白血病 / GATA転写因子 / T-ALL / CD34陽性細胞 / 同種骨髄移植 / HLA不適合ドナ- / 移植片対宿主病 … More / 抗LFAー1抗体 / マウスモノクロ-ナル抗体 / ELISA法 / 同権骨髄移植 / 骨髓移植 / 酵素免疫法(ELISA) / リンパ球芽球化反応 / T細胞 / allogeneic BMT / HLA-nonidentical dorno / GVHD / anti-CD11a / LFA-1 antibody / mouse monoclonal antibody / enzyme-linked immunosrobent assay / HLAハプロタイプ / 組織適合成 / 免疫不全症 / フローサイトメトリー / T細胞除去 / NK活性 / 寛容 / HLA / リンパ球膜分化抗原 / 白血病 / Bone marrow transplantation / HLA-haplotype / histoincompability / I cell-depleted immunodeficiency / flow cytometry / NK activity / LFAー1 / 移植片拒絶 / 単クロ-ン抗体 / HLA不一致 / CD_<11>a / CD_<18> / モノクローナル抗体 / bone marrow transplantation / graft rejection / HLA-mismatch / monoclonal antibody … More
Except Principal Investigator
GM-CSF / 造血幹細胞 / HEMATOPOIETIC STEM CELLS / XSCID / シグナル伝達 / BCR / ABL / gp91-phox / p47-phox / レトロウイルスベクター / アポトーシス / WASP / IgD / 白血球 / 粘着蛋白質 / CD11 / CD18 / Fcレセプタ- / ケミルミネセンス / ロタウィルス / 赤血球凝集素 / 単クローン抗体 / 抗イディオタイプ抗体 / 抗 イディオ-イディオタイプ抗体 / ワクチン / 伴性無ガンマグロブリン血症 / クロ-ナル・トランスフォ-メ-ション / エプスタイル・バン ウイルス / IgD産生細胞株 / κーλ鎖2重産生株 / B細胞増殖因子 / エプスタイン・バ-ウィルス / 無ガンマグロブリン血症 / エプスタイン-・バ-ウィルス / 未熟B細胞株 / K-λダブルプロデュ-サ- / X linked agammaglobulinemia / Clonal transformation / Epstein-Barr virus / IgD producer / kappa-lambda double producer / B cell growth factor / 未熟骨髄性白血病細胞株 / 支持細胞依存性 / 液性因子 / 末熟骨髄性白血病細胞株 / GMーCSF / IMMATURE MYELOYD LEUKEMIA CELL LINE / FEEDER CELL DEPENDENCY / SOLUBLE FACTOR / インターロイキン2(IL-2) / IL-2受容体 / サイトカイン / T細胞分化増殖 / チロシンキナーゼ / ノックアウトマウス / インターロイキン2 (IL-2) / サイイトカイン / γ鎖ノックアウトマウス / IL-2 / γ鎖 / JAK1,3 / interleukin 2 (IL-2) / IL-2 receptor / cytokine / T cell differntiation and growth / tyrosine kinase / knockout mice / c-kit / IL-2レセプターγ鎖 / エレクトロポレーション / 遺伝子導入 / IL-2セレプターγ鎖 / CD34 / 免疫磁気ビーズ / 白血病細胞株 / bcr / abl / c-Kit / C-KIT / IL-2 RECEPTOR gamma CHAIN / ELECTROPORATION / GENE TRANSFECTION / 慢性肉芽腫症 / 好中球 / 活性酸素 / 好酸球 / βアクチン / 食細胞 / シトクロム / β-アクチン / 高IgE症候群 / CGD / 白血球粘着不全症 / 細胞内アクチン異常症 / 遺伝性疾患 / Chronic granulomatous disease / neutrophil / superoxide / eosinophil / beta-actin / phagocyte / Wiskott-Aldrich症候群 / 遺伝子診断 / 保因者診断 / マウス抗WASP単クローン抗体 / Wiskott-aldrich症候群 / Wiskott-Aldrich syndrome / gene diagnosis / carrier detection / mouse anti-WASP monoclonal antibody / 神経芽細胞腫 / 細胞株 / 細胞接着分子 / インテグリン / インターフェロンα / Neuroblastoma / Cell line / Adhesion molecule / Integrins / Signal Transduction / インターロイキン15 / 急性移植片対宿主病 / γc鎖 / NK細胞 / リーダー配列 / X連鎖重症複合免疫不全症 / interleukin-15 / acute GVHD / gammac chain / NK cell / retrovirus vector / 先天性無ガンマグロブリン血症 / Bリンパ芽球様細胞株 / B細胞関連抗原 / モノクローナル抗体 / 細胞クローニング / K+λ産生細胞クローン / K+入鎖産生細胞クローン / EBウイルス / プレBリンパ芽球様細胞株 / 表面マーカー / congenital agammaglobulinemia / Precursor B cell line Less
  • Research Projects

    (15 results)
  • Co-Researchers

    (24 People)
  •  Development of a tumor vaccine using a membrane attached form of interleukin-15Principal Investigator

    • Principal Investigator
      MINEGISHI Masayoshi, 今野 多助
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Tohoku University
  •  Analysis of molecular mechanism of inherited phagocyte disorders.

    • Principal Investigator
      KANEGASAKI Shiro
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      内科学一般
    • Research Institution
      The University of Tokyo
  •  Function of the gene of Wiskott-Aldrich syndrome

    • Principal Investigator
      TSUCHIYA Shigeru
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pediatrics
    • Research Institution
      Tohoku University
  •  Regulatory Factors for Growth or Apoptosis of Neuroblastoma Cells and Its Therapeutic Application

    • Principal Investigator
      MINEGISHI Masayoshi
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Tohoku University
  •  Study of mechanism of X-licombined immunodeficiency caused by mutations of the IL-2 receptor gamma chain

    • Principal Investigator
      SUGAMURA Kazuo
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Immunology
    • Research Institution
      Tohoku University
  •  PURIFICATION OF HEMATOPOIETIC STEM CELLS BY A CD117 MONOCLONAL ANTIBODY,MTK1, IN ORDER TO TRANSFECT HUMAN GENES-A PRELIMINARY STUDY

    • Principal Investigator
      TSUCHIYA Shigeru
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Pediatrics
    • Research Institution
      INSTITUTE FOR DEVELOPMENT,AGING AND CANCER (IDAC) Tohoku University
  •  小児白血病細胞におけるGATA転写因子郡の発現に関する研究Principal Investigator

    • Principal Investigator
      今野 多助
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Tohoku University
  •  ESTABLISHMENT AND CHARACTERIZATION OF AN IMMATURE MYELOID CELL LINE, M-MOK, GROWN IN THE PRESENCE OF FIBROBLAST-FEEDER CELLS

    • Principal Investigator
      TSUCHIYA Shigeru
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Pediatrics
    • Research Institution
      RESEARCH INSTITUTE FOR TUBERCULOSIS AND CANCER, TOHOKU UNIVERSITY (RITC,TU)
  •  In vivo infusion of anti-CD11a/LFA-1 antibody for prevention and treatment of severe GVHD in HLA-nonidentical bone marrow transplantation : Its serum concentrations and biological effects.Principal Investigator

    • Principal Investigator
      KONNO Tasuke
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Pediatrics
    • Research Institution
      Tohoku University
  •  CD11/CD18欠損白血球の1gGFcレセプタ-の発現異常とその病態との関連

    • Principal Investigator
      SATO Tetsuo
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Tohoku University
  •  Abnormal Immunoglobulin in a Patient with X-Linked Agammaglobulinemia

    • Principal Investigator
      TSUCHIYA shigeru
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Pediatrics
    • Research Institution
      Tohoku University
  •  抗イデイオタイプ抗体を用いたヒトロタウィルス感染成立機序の解析

    • Principal Investigator
      佐藤 徹雄
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Tohoku University
  •  Anti-human LFA-1 monoclonal antibodies for prevention of graft failure in HLA-mismatched bone marrow transplantation.Principal Investigator

    • Principal Investigator
      KONNO Tasuke
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Pediatrics
    • Research Institution
      Tohoku University
  •  Etiology of congenital agammaglobulinemia: Growth defect of precursor B lymphoblastoid cell lines and immunoglobulin gene rearrangements.

    • Principal Investigator
      TSUCHIYA Shigeru
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Pediatrics
    • Research Institution
      TOHOKU UNIVERSITY
  •  Studies on Immunologic Reconstitution after HLA-haplotype Mismatched parental Marrow TransplantationPrincipal Investigator

    • Principal Investigator
      KONNO Tasuke
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Pediatrics
    • Research Institution
      TOHOKU UNIVERSITY
  • 1.  MASAYOSHI Minegishi (20211592)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 0 results
  • 2.  TSUCHIYA shigeru (30124605)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 0 results
  • 3.  SATO Tetsuo (90170761)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 4.  MASAHIKO Terasawa (80192201)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 5.  FUJIE Hiromi (60282000)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  MINEGISHI Naoko
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  SUGAMURA Kazuo (20117360)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  KASAI Noriyuki (60001947)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  ASAO Hironobu (80250744)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  OHASHI Yoshiyuki (60250825)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  KANEGASAKI Shiro (10012767)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  NUNOI Hiroyuki (50218260)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  KOMIYAMA Jun (50020798)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  KITAGAWA Seiichi (50133278)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  SENDO Fujiro (80091833)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  KOBAYASHI Kunihiko (60091451)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  大保 和之 (70250751)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  竹重 公一朗 (10037450)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  小林 陽之助 (50034062)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  洲崎 健 (90134048)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  土屋 滋 (90142934)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  KUMAKI Satoru
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  YAMAGUTI Yosiko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  TERASAWA Masahiko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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