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HAYASHI Kyozo
林 恭三
Connect your ORCID iD
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Researcher Number
00029935
Affiliation (Current)
2020: 岐阜薬科大学, その他部局等, 名誉教授
Affiliation (based on the past Project Information)
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1994 – 1996: Gifu Pharmaceutical University Pharmacy, Professor Emeritus, 薬学部, 名誉教授
1993 – 1995: 岐阜薬科大学, 教授
1987 – 1994: Professor: Gifu Pharmaceutical University, 薬学部, 教授
1991: Gifu Pharmaceutical Univ. Prof., 教授
1989: 岐阜薬科大学, 薬剤学, 教授
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1988: 岐阜薬科大学, 薬剤学講座, 教授
1987: 岐阜薬科大学, 薬剤学, 教授
1986: 岐薬大, 薬学部, 教授
1986: 岐阜薬科大学, 教授
Less
Review Section/Research Field
Principal Investigator
Neurology
/
Biological pharmacy
Except Principal Investigator
Functional biochemistry
/
Pathological medical chemistry
/
Orthopaedic surgery
/
Bioorganic chemistry
/
医薬分子機能学
/
Neurology
Keywords
Principal Investigator
nerve growth factor (NGF) / ヘビ神経毒 / 抗体 / 酵素免疫測定法 / diagnosis / enzyme immunoassay (EIA) / 老人痴呆症 / 糖鎖 / 結合定数 / アストログリア細胞
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More
/ 糖鎖構造 / シビレエイ / 老人痴呆 / 神経成長因子(NGF) / 酵素免疫測定法(EIA) / 測定感度 / コリン作動性ニュ-ロン / 診断 / Alzheimer's disease / cholinergic nerve cells / 神経栄養因子 / NGF / NT-3 / 早期診断法 / ニコチン性アセチルコリン受容体 / 神経伝達 / Carbohydrate Structure / ホスホリパ-ゼA_2 / Ca^<2+>依存性複合体 / スフィンゴミエリン / 金属イオン / ランタニドイオン / 触媒中心 / 触媒効率 / ホスホリパーゼA_2 / カルシウムイオン / 酵素反応速度論 / ミセル状基質 / 単分子散状基質 / 基質アナログ / 酵素・基質複合体 / 神経成長促進因子(NGF) / 線維芽細胞 / アドレナリン作動性受容体 / カテコールアミン / 合成促進効果 / 構造活性相関 / コリン作動性ニューロン / ニコチン性アセチルコリン受容体(AchR) / 重症筋無力症(MG) / 神経伝達物質 / 糖タンパク / 神経栄養因子(NTF) / 塩基性線維芽細胞増殖因子(bFGF) / 血中レベル / ヒト線維芽細胞 / 抗ヒトNGF抗体 / ヒト神経成長因子 / 線維芽細胞増殖因子 / 抗ヒト神経成長因子抗体 / 開発 / degeneration / human fibroblast (WS-1) cells / anti-recombinant human NGF antibody IgG / 神経回路網 / サイトカイン / 神経細胞 / 修復機能維持 / EIA / Alzheimer型老人痴呆症 / コリンアセチルトランスフェラーゼ(CAT) / 生合成 / 制御機構 / neurotrophic factor / coenzyme / astrocytes / forebrain-lesioned rat / NGF synthesis stimulation / interleukin / GFGF / 酵素免疫側定法(EIA) / 最少検出量 / 再現性 / 特異性 / bFGF / neurotrophin-3 (NT-3) / neurotrophic factor (NTF) / serum / cerebrospinal fluid / periphral tissue / ハイマンノース型 / 分子量43,000蛋白群 / プロテインキナーゼ / クレアチンキナーゼ / ニコチン性アセチルコリン受容体(AChR) / ハイマンノース型糖鎖 / コンプレックス型糖鎖 / コリン性ガンド / αブンガロトキシン / 43k蛋白 / Nicotinic Acetylcholine Receptor (nAChR); Neurotransmission / High-Mannose Type / Molecular Weight 43,000 Proteins / Protein Kinase / Creatine Kinase / 43K蛋白質 / リン酸化 / 脱感作 / プロテインキナ-ゼ / クレアチンキナ-ゼ / 神経筋接合部 / 機能発見 / コリン性リガンド / 43kタンパク質 / 架橋形成 / 分子機構 / リン酸化チロシン / 43κ蛋白 / キナーゼ / Nicotinic Acetylcholine Receptor (nAChR) / Glycoprotein / Function / Phosphorylation / 43KDa Proteins / Desensitization / Neurotransmission / 高齢化社会 / 神経成長因子 / 上皮細胞増殖因子 / ス-パ-オキシドディスムタ-ゼ / 老人痴呆塩 / 神経成長促進因子 / 線維芽細胞成長因子 / アミロイド蛋白 / 早期診断 / Alzhermer's disease / superoxide dismutase (SOD) / enzyme immunoassay system (EIA) / antibody / astoglial cells
…
More
Except Principal Investigator
神経成長因子 / NGF / 神経栄養因子 / 受容体 / アストログリア細胞 / 腫瘍壊死因子 / 創傷修復 / 繊維芽細胞 / インターロイキン-1 / 骨形成因子 / P_<400>蛋白質 / IP_3受容体 / staggererミュータントマウス / プルキンエ細胞 / 初代培養神経細胞 / 神経突起伸展因子 / ミエリン形成 / 小脳プルキニエ細胞 / シュワン細胞 / 細胞増殖・分化制御 / 細胞増殖因子 / MAPキナーゼ / シグナル伝達 / 蛋白質リン酸化反応 / 分子細胞生物学 / 転写調節領域 / プロセシング / 細胞膜 / 膜酵素 / 活性酸素 / プロスタグランジン / イノシトールポリ燐酸 / 燐酸化 / ニューロン・グリア / 形態形成 / 細胞接着分子 / ミュータント / 神経分化 / 複合糖質 / 糖鎖構造 / 糖鎖の多様性 / 糖鎖と病態 / モノクロ-ナル抗体 / 糖鎖抗原 / Glycocojugates, / Oligosaccharide structure / Polymorphism of oligosac-charides / 脊髄 / 脊髄損傷 / 神経再生 / NGF合成促進 / nerve growth factor / spinal cord / degeneration of spinal cord / regeneration of nerve / 老人性痴呆 / アルツハイマー型痴呆 / 化学選択的精製法 / ジスルフィド形成反応 / Trk受容体 / Tau蛋白質 / 非水解性リン酸化ペプチド / NGF合成促進因子 / アルツハイマー / フラグメント縮合 / 二価官能性試薬 / 化学選択的固定化 / ジメチルスルホキシド / ジスルフィド形成 / 老人性痴呆症 / Biotin化試薬 / アフィニテイークロマト / Arg-vasopressin(4-9) / Senile Dementia / Alzheimer Disase / Neurotrophin / Chemoselective Purification / Disulfide-bond Formation / Trk-receptor / Tau-protein / Nonhydrolyzable Phosophopeptide / 末梢神経再生 / Tumor Necrosis factor-alpha / Nerve Growth Factor / Wound healing / Fibroblasts / Interleukin-1 / Bone Morphogenetic Protein / Receptor / Nerve regeneration / 末梢神経 / 中枢神経 / 脳 / 海馬 / 皮質 / 交感神経 / 神経細胞 / 合成誘導 / 大細胞性コリン作動性神経細胞 / 前脳基底核 / 分化 / ホモカテコール / アルキルカテコール / カテコールアミン / アストロサイト / ニューロン
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Research Projects
(
21
results)
Co-Researchers
(
38
People)
Project Start Year (Newest)
Project Start Year (Oldest)
創傷修復過程における末梢神経再生の分子機構-腫瘍壊死因子によるNGF遺伝子の発現制御
Principal Investigator
河野 通明
Project Period (FY)
1995
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Functional biochemistry
Research Institution
Gifu Pharmaceutical University
Development of anti-skin ulcer drug based on the new concept -Application of the stimulatory effect of TNF-alpha on the production of NGF in fibroblasts
Principal Investigator
KOHNO Michiaki
Project Period (FY)
1995 – 1996
Research Category
Grant-in-Aid for Scientific Research (A)
Research Field
医薬分子機能学
Research Institution
Gifu Pharmaceutical University
細胞増殖因子作用における41-kDa、43-kDa・MAPキナーゼ活性化の役割
Principal Investigator
KOHNO Michiaki
Project Period (FY)
1993
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Functional biochemistry
Research Institution
Gifu Pharmaceutical University
Development of the Enzyme Immunoassay System for the Substances Related to the Pathogenesis of Alzheimer's Disease
Principal Investigator
Principal Investigator
HAYASHI Kyozo
Project Period (FY)
1993 – 1994
Research Category
Grant-in-Aid for Developmental Scientific Research (B)
Research Field
Neurology
Research Institution
Gifu Pharmaceutical University
Synthetic Study on Neurotrophins and Its Application for Development of Diagnostic Immunoassay Method for Senile Dementia
Principal Investigator
FUJII Nobutaka
Project Period (FY)
1993 – 1995
Research Category
Grant-in-Aid for Developmental Scientific Research (B)
Research Field
Bioorganic chemistry
Research Institution
KYOTO UNIVERSITY
ホスホリパーゼA_2におけるCa^<2+>結合部位の動的構造と機能発現メカニズムの解明
Principal Investigator
Principal Investigator
林 恭三
Project Period (FY)
1992
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Gifu Pharmaceutical University
Studies on the molecular biology of the relationship between neurotrophin which functions to central nervous system (CNS) and Alzheimer's disease (AD)
Principal Investigator
Principal Investigator
HAYASHI Kyozo
Project Period (FY)
1992 – 1993
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Neurology
Research Institution
Gifu Pharmaceutical University
ホスホリパ-ゼA_2におけるCa^<2+>結合の動的構造と機能発現メカニズムの解明
Principal Investigator
Principal Investigator
林 恭三
Project Period (FY)
1991
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Gifu Pharmaceutical University
Stimulation of spinal cord regeneration by stimulator of NGF synthesis
Principal Investigator
FURUKAWA Yoshiko
Project Period (FY)
1991 – 1992
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Orthopaedic surgery
Research Institution
Gifu Pharmaceutical University
ニュ-ロン・グリア関認識の分子機構
Principal Investigator
畠中 寛
Project Period (FY)
1990
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Osaka University
Develpment of the Enzyme Immunoassay System for the Substances Related to the Pathogenesis of Alzheimer's Disease
Principal Investigator
Principal Investigator
HAYASHI Kyozo
Project Period (FY)
1990 – 1991
Research Category
Grant-in-Aid for Developmental Scientific Research (B)
Research Field
Neurology
Research Institution
Gifu Pharmaceutical University
ニューロン・グリア間認識の分子機構
Principal Investigator
御子柴 克彦
Project Period (FY)
1989
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Osaka University
Polymorphism of oligosaccharide structure in glycoconjugaates
Principal Investigator
TAKAHASHI Noriko
Project Period (FY)
1989 – 1991
Research Category
Grant-in-Aid for Co-operative Research (A)
Research Field
Pathological medical chemistry
Research Institution
Nagoya City University College of Nursing
Biochemical Studies on the Molecular Mechanism of Neurotransmission, Centered on Nicotinic Acetylcholine Receptor (nAChR)
Principal Investigator
Principal Investigator
HAYASHI Kyozo
Project Period (FY)
1988 – 1989
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Neurology
Research Institution
Gifu Pharmaceutical University
Development of the Enzyme Immunoassay Systems for the Substances Involved in the Cause of Alzheimer's Disease
Principal Investigator
Principal Investigator
HAYASHI Kyozo
Project Period (FY)
1988 – 1989
Research Category
Grant-in-Aid for Developmental Scientific Research
Research Field
Neurology
Research Institution
Gifu Pharmaceutical University
アセチルコリン受容体の機能発現に関する化学的研究
Principal Investigator
Principal Investigator
林 恭三
Project Period (FY)
1987
Research Category
Grant-in-Aid for Special Project Research
Research Institution
Gifu Pharmaceutical University
神経成長因子(NGF)合成促進薬物の抗痴呆薬としての応用・開発する研究
Principal Investigator
古川 昭栄
Project Period (FY)
1987 – 1988
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Neurology
Research Institution
National Center of Neurology and Psychiatry
細胞膜とその機能発現
Principal Investigator
山本 尚三
Project Period (FY)
1986
Research Category
Grant-in-Aid for Special Project Research
Research Institution
The University of Tokushima
神経成長促進因子の生成と存在様式に関する生化学的研究
Principal Investigator
Principal Investigator
林 恭三
Project Period (FY)
1986
Research Category
Grant-in-Aid for Special Project Research
Research Institution
Gifu Pharmaceutical University
ニューロン・グリア間認識の分子機構
Principal Investigator
御子柴 克彦
Project Period (FY)
1986 – 1988
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Osaka University
Biochemical Studies on the Mechanism of Neurotransmission--- Principally Structure-Function Relationship of Nicotinic Acetylcholine Receptor ---
Principal Investigator
Principal Investigator
HAYASHI Kyozo
Project Period (FY)
1986 – 1987
Research Category
Grant-in-Aid for General Scientific Research (A)
Research Field
Biological pharmacy
Research Institution
Gifu Pharmaceutical University
# of Projects (Dsc)
# of Projects (Asc)
1.
FURUKAWA Shoei
(90159129)
# of Collaborated Projects:
10 results
# of Collaborated Products:
0 results
2.
FURUKAWA Yoshiko
(20219108)
# of Collaborated Projects:
5 results
# of Collaborated Products:
0 results
3.
NOMOTO Hiroshi
(80164747)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
4.
KOHNO Michiaki
(00027335)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
5.
田中 亮
(90094383)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
6.
SATO Masahiro
(00240945)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
7.
HIRANO Kazuyuki
(90057365)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
8.
MORI Kazutoshi
(70182194)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
9.
花岡 和則
(40189577)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
10.
畠中 寛
(60208519)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
11.
三木 直正
(40094445)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
12.
NISHITANI Hiroshi
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
13.
ADACHI Tetsuo
(40137063)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
14.
御子柴 克彦
(30051840)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
15.
池田 潔
(50001053)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
16.
HIRATANI Hajime
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
17.
TAKAHASHI Noriko
(90079989)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
18.
KANNAGI Reiji
(80161389)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
19.
ISHIHARA Hideko
(90080192)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
20.
NAKASHIMA Izumi
(40022826)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
21.
ARATA Yoji
(40011499)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
22.
NAKAMURA Nobuyuki
(90198226)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
23.
FUJII Nobutaka
(60109014)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
24.
IIDA Akira
(40202816)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
25.
TAMAMURA Hirokazu
(80217182)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
26.
TAKIGAWA Masahiro
(80115873)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
27.
植村 慶一
(90049792)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
28.
山本 尚三
(50025607)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
29.
室田 誠逸
(50072989)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
30.
水上 茂樹
(90037325)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
31.
松田 佳子
(40035449)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
32.
藤多 哲朗
(40027024)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
33.
西川 徹
(00198441)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
34.
NAGAOKA Akinobu
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
35.
FUJIMOTO Masafumi
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
36.
NAKAZATO Hiroshi
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
37.
太田 光煕
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
38.
辻本 雅文
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
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