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HAYASHI Kyozo  林 恭三

ORCIDConnect your ORCID iD *help
Researcher Number 00029935
Affiliation (Current) 2022: 岐阜薬科大学, その他部局等, 名誉教授
Affiliation (based on the past Project Information) *help 1994 – 1996: Gifu Pharmaceutical University Pharmacy, Professor Emeritus, 薬学部, 名誉教授
1993 – 1995: 岐阜薬科大学, 教授
1987 – 1994: Professor: Gifu Pharmaceutical University, 薬学部, 教授
1991: Gifu Pharmaceutical Univ. Prof., 教授
1989: 岐阜薬科大学, 薬剤学, 教授 … More
1988: 岐阜薬科大学, 薬剤学講座, 教授
1987: 岐阜薬科大学, 薬剤学, 教授
1986: 岐薬大, 薬学部, 教授
1986: 岐阜薬科大学, 教授 Less
Review Section/Research Field
Principal Investigator
Neurology / Biological pharmacy
Except Principal Investigator
Functional biochemistry / Pathological medical chemistry / Orthopaedic surgery / Bioorganic chemistry / 医薬分子機能学 / Neurology
Keywords
Principal Investigator
nerve growth factor (NGF) / ヘビ神経毒 / 抗体 / 酵素免疫測定法 / diagnosis / enzyme immunoassay (EIA) / 老人痴呆症 / 糖鎖 / 結合定数 / アストログリア細胞 … More / 糖鎖構造 / シビレエイ / 老人痴呆 / 神経成長因子(NGF) / 酵素免疫測定法(EIA) / 測定感度 / コリン作動性ニュ-ロン / 診断 / Alzheimer's disease / cholinergic nerve cells / 神経栄養因子 / NGF / NT-3 / 早期診断法 / ニコチン性アセチルコリン受容体 / 神経伝達 / Carbohydrate Structure / ホスホリパ-ゼA_2 / Ca^<2+>依存性複合体 / スフィンゴミエリン / 金属イオン / ランタニドイオン / 触媒中心 / 触媒効率 / ホスホリパーゼA_2 / カルシウムイオン / 酵素反応速度論 / ミセル状基質 / 単分子散状基質 / 基質アナログ / 酵素・基質複合体 / 神経成長促進因子(NGF) / 線維芽細胞 / アドレナリン作動性受容体 / カテコールアミン / 合成促進効果 / 構造活性相関 / コリン作動性ニューロン / ニコチン性アセチルコリン受容体(AchR) / 重症筋無力症(MG) / 神経伝達物質 / 糖タンパク / 神経栄養因子(NTF) / 塩基性線維芽細胞増殖因子(bFGF) / 血中レベル / ヒト線維芽細胞 / 抗ヒトNGF抗体 / ヒト神経成長因子 / 線維芽細胞増殖因子 / 抗ヒト神経成長因子抗体 / 開発 / degeneration / human fibroblast (WS-1) cells / anti-recombinant human NGF antibody IgG / 神経回路網 / サイトカイン / 神経細胞 / 修復機能維持 / EIA / Alzheimer型老人痴呆症 / コリンアセチルトランスフェラーゼ(CAT) / 生合成 / 制御機構 / neurotrophic factor / coenzyme / astrocytes / forebrain-lesioned rat / NGF synthesis stimulation / interleukin / GFGF / 酵素免疫側定法(EIA) / 最少検出量 / 再現性 / 特異性 / bFGF / neurotrophin-3 (NT-3) / neurotrophic factor (NTF) / serum / cerebrospinal fluid / periphral tissue / ハイマンノース型 / 分子量43,000蛋白群 / プロテインキナーゼ / クレアチンキナーゼ / ニコチン性アセチルコリン受容体(AChR) / ハイマンノース型糖鎖 / コンプレックス型糖鎖 / コリン性ガンド / αブンガロトキシン / 43k蛋白 / Nicotinic Acetylcholine Receptor (nAChR); Neurotransmission / High-Mannose Type / Molecular Weight 43,000 Proteins / Protein Kinase / Creatine Kinase / 43K蛋白質 / リン酸化 / 脱感作 / プロテインキナ-ゼ / クレアチンキナ-ゼ / 神経筋接合部 / 機能発見 / コリン性リガンド / 43kタンパク質 / 架橋形成 / 分子機構 / リン酸化チロシン / 43κ蛋白 / キナーゼ / Nicotinic Acetylcholine Receptor (nAChR) / Glycoprotein / Function / Phosphorylation / 43KDa Proteins / Desensitization / Neurotransmission / 高齢化社会 / 神経成長因子 / 上皮細胞増殖因子 / ス-パ-オキシドディスムタ-ゼ / 老人痴呆塩 / 神経成長促進因子 / 線維芽細胞成長因子 / アミロイド蛋白 / 早期診断 / Alzhermer's disease / superoxide dismutase (SOD) / enzyme immunoassay system (EIA) / antibody / astoglial cells … More
Except Principal Investigator
神経成長因子 / NGF / 神経栄養因子 / 受容体 / アストログリア細胞 / 腫瘍壊死因子 / 創傷修復 / 繊維芽細胞 / インターロイキン-1 / 骨形成因子 / P_<400>蛋白質 / IP_3受容体 / staggererミュータントマウス / プルキンエ細胞 / 初代培養神経細胞 / 神経突起伸展因子 / ミエリン形成 / 小脳プルキニエ細胞 / シュワン細胞 / 細胞増殖・分化制御 / 細胞増殖因子 / MAPキナーゼ / シグナル伝達 / 蛋白質リン酸化反応 / 分子細胞生物学 / 転写調節領域 / プロセシング / 細胞膜 / 膜酵素 / 活性酸素 / プロスタグランジン / イノシトールポリ燐酸 / 燐酸化 / ニューロン・グリア / 形態形成 / 細胞接着分子 / ミュータント / 神経分化 / 複合糖質 / 糖鎖構造 / 糖鎖の多様性 / 糖鎖と病態 / モノクロ-ナル抗体 / 糖鎖抗原 / Glycocojugates, / Oligosaccharide structure / Polymorphism of oligosac-charides / 脊髄 / 脊髄損傷 / 神経再生 / NGF合成促進 / nerve growth factor / spinal cord / degeneration of spinal cord / regeneration of nerve / 老人性痴呆 / アルツハイマー型痴呆 / 化学選択的精製法 / ジスルフィド形成反応 / Trk受容体 / Tau蛋白質 / 非水解性リン酸化ペプチド / NGF合成促進因子 / アルツハイマー / フラグメント縮合 / 二価官能性試薬 / 化学選択的固定化 / ジメチルスルホキシド / ジスルフィド形成 / 老人性痴呆症 / Biotin化試薬 / アフィニテイークロマト / Arg-vasopressin(4-9) / Senile Dementia / Alzheimer Disase / Neurotrophin / Chemoselective Purification / Disulfide-bond Formation / Trk-receptor / Tau-protein / Nonhydrolyzable Phosophopeptide / 末梢神経再生 / Tumor Necrosis factor-alpha / Nerve Growth Factor / Wound healing / Fibroblasts / Interleukin-1 / Bone Morphogenetic Protein / Receptor / Nerve regeneration / 末梢神経 / 中枢神経 / 脳 / 海馬 / 皮質 / 交感神経 / 神経細胞 / 合成誘導 / 大細胞性コリン作動性神経細胞 / 前脳基底核 / 分化 / ホモカテコール / アルキルカテコール / カテコールアミン / アストロサイト / ニューロン Less
  • Research Projects

    (21 results)
  • Co-Researchers

    (38 People)
  •  創傷修復過程における末梢神経再生の分子機構-腫瘍壊死因子によるNGF遺伝子の発現制御

    • Principal Investigator
      河野 通明
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Functional biochemistry
    • Research Institution
      Gifu Pharmaceutical University
  •  Development of anti-skin ulcer drug based on the new concept -Application of the stimulatory effect of TNF-alpha on the production of NGF in fibroblasts

    • Principal Investigator
      KOHNO Michiaki
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      医薬分子機能学
    • Research Institution
      Gifu Pharmaceutical University
  •  細胞増殖因子作用における41-kDa、43-kDa・MAPキナーゼ活性化の役割

    • Principal Investigator
      KOHNO Michiaki
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Functional biochemistry
    • Research Institution
      Gifu Pharmaceutical University
  •  Development of the Enzyme Immunoassay System for the Substances Related to the Pathogenesis of Alzheimer's DiseasePrincipal Investigator

    • Principal Investigator
      HAYASHI Kyozo
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      Gifu Pharmaceutical University
  •  Synthetic Study on Neurotrophins and Its Application for Development of Diagnostic Immunoassay Method for Senile Dementia

    • Principal Investigator
      FUJII Nobutaka
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Bioorganic chemistry
    • Research Institution
      KYOTO UNIVERSITY
  •  ホスホリパーゼA_2におけるCa^<2+>結合部位の動的構造と機能発現メカニズムの解明Principal Investigator

    • Principal Investigator
      林 恭三
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Gifu Pharmaceutical University
  •  Studies on the molecular biology of the relationship between neurotrophin which functions to central nervous system (CNS) and Alzheimer's disease (AD)Principal Investigator

    • Principal Investigator
      HAYASHI Kyozo
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      Gifu Pharmaceutical University
  •  ホスホリパ-ゼA_2におけるCa^<2+>結合の動的構造と機能発現メカニズムの解明Principal Investigator

    • Principal Investigator
      林 恭三
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Gifu Pharmaceutical University
  •  Stimulation of spinal cord regeneration by stimulator of NGF synthesis

    • Principal Investigator
      FURUKAWA Yoshiko
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Gifu Pharmaceutical University
  •  ニュ-ロン・グリア関認識の分子機構

    • Principal Investigator
      畠中 寛
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  Develpment of the Enzyme Immunoassay System for the Substances Related to the Pathogenesis of Alzheimer's DiseasePrincipal Investigator

    • Principal Investigator
      HAYASHI Kyozo
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      Gifu Pharmaceutical University
  •  ニューロン・グリア間認識の分子機構

    • Principal Investigator
      御子柴 克彦
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  Polymorphism of oligosaccharide structure in glycoconjugaates

    • Principal Investigator
      TAKAHASHI Noriko
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Nagoya City University College of Nursing
  •  Biochemical Studies on the Molecular Mechanism of Neurotransmission, Centered on Nicotinic Acetylcholine Receptor (nAChR)Principal Investigator

    • Principal Investigator
      HAYASHI Kyozo
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      Gifu Pharmaceutical University
  •  Development of the Enzyme Immunoassay Systems for the Substances Involved in the Cause of Alzheimer's DiseasePrincipal Investigator

    • Principal Investigator
      HAYASHI Kyozo
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for Developmental Scientific Research
    • Research Field
      Neurology
    • Research Institution
      Gifu Pharmaceutical University
  •  アセチルコリン受容体の機能発現に関する化学的研究Principal Investigator

    • Principal Investigator
      林 恭三
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      Gifu Pharmaceutical University
  •  神経成長因子(NGF)合成促進薬物の抗痴呆薬としての応用・開発する研究

    • Principal Investigator
      古川 昭栄
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      National Center of Neurology and Psychiatry
  •  細胞膜とその機能発現

    • Principal Investigator
      山本 尚三
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      The University of Tokushima
  •  神経成長促進因子の生成と存在様式に関する生化学的研究Principal Investigator

    • Principal Investigator
      林 恭三
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      Gifu Pharmaceutical University
  •  ニューロン・グリア間認識の分子機構

    • Principal Investigator
      御子柴 克彦
    • Project Period (FY)
      1986 – 1988
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  Biochemical Studies on the Mechanism of Neurotransmission--- Principally Structure-Function Relationship of Nicotinic Acetylcholine Receptor ---Principal Investigator

    • Principal Investigator
      HAYASHI Kyozo
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Biological pharmacy
    • Research Institution
      Gifu Pharmaceutical University
  • 1.  FURUKAWA Shoei (90159129)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 0 results
  • 2.  FURUKAWA Yoshiko (20219108)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 3.  NOMOTO Hiroshi (80164747)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 4.  KOHNO Michiaki (00027335)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 5.  田中 亮 (90094383)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 6.  SATO Masahiro (00240945)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 7.  HIRANO Kazuyuki (90057365)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 8.  MORI Kazutoshi (70182194)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 9.  花岡 和則 (40189577)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 10.  畠中 寛 (60208519)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 11.  三木 直正 (40094445)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 12.  NISHITANI Hiroshi
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 13.  ADACHI Tetsuo (40137063)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  御子柴 克彦 (30051840)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 15.  池田 潔 (50001053)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 16.  HIRATANI Hajime
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 17.  TAKAHASHI Noriko (90079989)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  KANNAGI Reiji (80161389)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  ISHIHARA Hideko (90080192)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  NAKASHIMA Izumi (40022826)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  ARATA Yoji (40011499)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  NAKAMURA Nobuyuki (90198226)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  FUJII Nobutaka (60109014)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  IIDA Akira (40202816)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  TAMAMURA Hirokazu (80217182)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  TAKIGAWA Masahiro (80115873)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  植村 慶一 (90049792)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  山本 尚三 (50025607)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  室田 誠逸 (50072989)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  水上 茂樹 (90037325)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  松田 佳子 (40035449)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  藤多 哲朗 (40027024)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  西川 徹 (00198441)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  NAGAOKA Akinobu
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  FUJIMOTO Masafumi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  NAKAZATO Hiroshi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 37.  太田 光煕
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 38.  辻本 雅文
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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