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HAYASHI Kyozo
林 恭三
Researcher Number
00029935
Affiliation
*help
1994 – 1996 : Gifu Pharmaceutical University Pharmacy, Professor Emeritus, 薬学部, 名誉教授
1994 – 1995 : 岐阜薬科大学, 名誉教授
1987 – 1994 : 岐阜薬科大学, 薬学部, 教授
1993 : 岐阜薬科大学, 教授
1991 : Gifu Pharmaceutical Univ. Prof., 教授
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1989 : 岐阜薬科大学, 薬剤学, 教授
1988 : 岐阜薬科大学, 薬剤学講座, 教授
1987 : 岐阜薬科大学, 薬剤学, 教授
1986 : 岐薬大, 薬学部, 教授
1986 : 岐阜薬科大学, 教授
Less
Research Field
Except Principal Investigator
Neurology
/
Functional biochemistry
/
Orthopaedic surgery
/
Pathological medical chemistry
/
Bioorganic chemistry
/
医薬分子機能学
/
Biological pharmacy
Keywords
Except Principal Investigator
神経成長因子 / NGF / 神経栄養因子 / アストログリア細胞 / nerve growth factor (NGF) / 糖鎖構造 / 酵素免疫測定法 / 糖鎖 / 受容体 / 老人痴呆症
…
More
/ ヘビ神経毒 / enzyme immunoassay (EIA) / diagnosis / 抗体 / cholinergic nerve cells / インターロイキン-1 / 繊維芽細胞 / 神経伝達 / カテコールアミン / 腫瘍壊死因子 / Alzheimer's disease / 老人痴呆 / 結合定数 / 神経成長因子(NGF) / 骨形成因子 / ニコチン性アセチルコリン受容体 / 測定感度 / 早期診断法 / NT-3 / Carbohydrate Structure / 創傷修復 / シビレエイ / コリン作動性ニュ-ロン / 診断 / 神経細胞 / 酵素免疫測定法(EIA) / P_<400>蛋白質 / IP_3受容体 / Protein Kinase / αブンガロトキシン / 制御機構 / 末梢神経 / Nicotinic Acetylcholine Receptor (nAChR); Neurotransmission / Biotin化試薬 / 構造活性相関 / 分化 / 前脳基底核 / 再現性 / 43κ蛋白 / 化学選択的固定化 / bFGF / 神経伝達物質 / Creatine Kinase / degeneration / ニューロン / 海馬 / human fibroblast (WS-1) cells / 転写調節領域 / 酵素免疫側定法(EIA) / アフィニテイークロマト / 43K蛋白質 / 蛋白質リン酸化反応 / nerve growth factor / 脊髄 / コリン性ガンド / 交感神経 / ジスルフィド形成反応 / 細胞増殖因子 / 皮質 / 老人性痴呆症 / 合成促進効果 / 早期診断 / ランタニドイオン / ハイマンノース型 / Nicotinic Acetylcholine Receptor (nAChR) / コリンアセチルトランスフェラーゼ(CAT) / 神経再生 / anti-recombinant human NGF antibody IgG / 大細胞性コリン作動性神経細胞 / プロテインキナ-ゼ / 神経回路網 / Nonhydrolyzable Phosophopeptide / シュワン細胞 / 機能発見 / 架橋形成 / イノシトールポリ燐酸 / クレアチンキナーゼ / High-Mannose Type / ニューロン・グリア / 分子細胞生物学 / 重症筋無力症(MG) / neurotrophin-3 (NT-3) / enzyme immunoassay system (EIA) / 神経成長促進因子(NGF) / 中枢神経 / Chemoselective Purification / Tau蛋白質 / ヒト神経成長因子 / 細胞増殖・分化制御 / 非水解性リン酸化ペプチド / 老人性痴呆 / Molecular Weight 43,000 Proteins / Trk受容体 / Receptor / 末梢神経再生 / regeneration of nerve / 金属イオン / ミュータント / コンプレックス型糖鎖 / 分子機構 / degeneration of spinal cord / MAPキナーゼ / 活性酸素 / アルツハイマー型痴呆 / ホスホリパーゼA_2 / Trk-receptor / NGF synthesis stimulation / フラグメント縮合 / 神経筋接合部 / 修復機能維持 / Glycocojugates, / ジスルフィド形成 / コリン作動性ニューロン / Glycoprotein / ヒト線維芽細胞 / ミエリン形成 / 血中レベル / staggererミュータントマウス / コリン性リガンド / astoglial cells / NGF合成促進因子 / 生合成 / Bone Morphogenetic Protein / 基質アナログ / ジメチルスルホキシド / 細胞膜 / キナーゼ / 神経成長促進因子 / 小脳プルキニエ細胞 / antibody / 糖タンパク / Nerve regeneration / 膜酵素 / periphral tissue / NGF合成促進 / 神経栄養因子(NTF) / アドレナリン作動性受容体 / 燐酸化 / Polymorphism of oligosac-charides / neurotrophic factor / Interleukin-1 / 43k蛋白 / spinal cord / アルツハイマー / 糖鎖抗原 / 神経分化 / ニコチン性アセチルコリン受容体(AchR) / カルシウムイオン / 糖鎖と病態 / スフィンゴミエリン / 複合糖質 / superoxide dismutase (SOD) / ホモカテコール / プルキンエ細胞 / GFGF / Oligosaccharide structure / 脱感作 / プロスタグランジン / アルキルカテコール / Tau-protein / アストロサイト / ミセル状基質 / 高齢化社会 / リン酸化 / Fibroblasts / 初代培養神経細胞 / 酵素反応速度論 / 塩基性線維芽細胞増殖因子(bFGF) / 触媒中心 / Tumor Necrosis factor-alpha / cerebrospinal fluid / リン酸化チロシン / プロテインキナーゼ / 最少検出量 / 形態形成 / 細胞接着分子 / Alzheimer Disase / Wound healing / ス-パ-オキシドディスムタ-ゼ / 合成誘導 / 線維芽細胞成長因子 / astrocytes / neurotrophic factor (NTF) / EIA / coenzyme / 神経突起伸展因子 / 抗ヒト神経成長因子抗体 / サイトカイン / 抗ヒトNGF抗体 / 開発 / serum / Senile Dementia / Function / Neurotransmission / 化学選択的精製法 / プロセシング / Alzhermer's disease / interleukin / ハイマンノース型糖鎖 / 脳 / 43KDa Proteins / Ca^<2+>依存性複合体 / Desensitization / モノクロ-ナル抗体 / 特異性 / 老人痴呆塩 / Disulfide-bond Formation / 単分子散状基質 / 触媒効率 / 酵素・基質複合体 / Alzheimer型老人痴呆症 / 二価官能性試薬 / Arg-vasopressin(4-9) / Phosphorylation / アミロイド蛋白 / 43kタンパク質 / 線維芽細胞増殖因子 / ホスホリパ-ゼA_2 / クレアチンキナ-ゼ / forebrain-lesioned rat / 上皮細胞増殖因子 / 分子量43,000蛋白群 / Nerve Growth Factor / シグナル伝達 / 糖鎖の多様性 / Neurotrophin / 脊髄損傷 / ニコチン性アセチルコリン受容体(AChR) / 線維芽細胞
Less
Research Projects
(
21
results)
Co-Researchers
(
39
People)
Project Start Year(Newest)
Project Start Year(Oldest)
Development of anti-skin ulcer drug based on the new concept -Application of the stimulatory effect of TNF-alpha on the production of NGF in fibroblasts
Principal Investigator
KOHNO Michiaki
Project Period (FY)
1995 – 1996
Research Category
Grant-in-Aid for Scientific Research (A)
Research Field
医薬分子機能学
Research Institution
Gifu Pharmaceutical University
創傷修復過程における末梢神経再生の分子機構-腫瘍壊死因子によるNGF遺伝子の発現制御
Principal Investigator
河野 通明
Project Period (FY)
1995
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Functional biochemistry
Research Institution
Gifu Pharmaceutical University
Development of the Enzyme Immunoassay System for the Substances Related to the Pathogenesis of Alzheimer's Disease
Principal Investigator
Principal Investigator
HAYASHI Kyozo
Project Period (FY)
1993 – 1994
Research Category
Grant-in-Aid for Developmental Scientific Research (B)
Research Field
Neurology
Research Institution
Gifu Pharmaceutical University
Synthetic Study on Neurotrophins and Its Application for Development of Diagnostic Immunoassay Method for Senile Dementia
Principal Investigator
FUJII Nobutaka
, 舩越 奨
Project Period (FY)
1993 – 1995
Research Category
Grant-in-Aid for Developmental Scientific Research (B)
Research Field
Bioorganic chemistry
Research Institution
KYOTO UNIVERSITY
細胞増殖因子作用における41-kDa、43-kDa・MAPキナーゼ活性化の役割
Principal Investigator
河野 通明
Project Period (FY)
1993
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Functional biochemistry
Research Institution
Gifu Pharmaceutical University
ホスホリパーゼA_2におけるCa^<2+>結合部位の動的構造と機能発現メカニズムの解明
Principal Investigator
Principal Investigator
林 恭三
Project Period (FY)
1992
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Gifu Pharmaceutical University
Studies on the molecular biology of the relationship between neurotrophin which functions to central nervous system (CNS) and Alzheimer's disease (AD)
Principal Investigator
Principal Investigator
HAYASHI Kyozo
Project Period (FY)
1992 – 1993
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Neurology
Research Institution
Gifu Pharmaceutical University
ホスホリパ-ゼA_2におけるCa^<2+>結合の動的構造と機能発現メカニズムの解明
Principal Investigator
Principal Investigator
林 恭三
Project Period (FY)
1991
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Gifu Pharmaceutical University
Stimulation of spinal cord regeneration by stimulator of NGF synthesis
Principal Investigator
FURUKAWA Yoshiko
Project Period (FY)
1991 – 1992
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Orthopaedic surgery
Research Institution
Gifu Pharmaceutical University
ニュ-ロン・グリア関認識の分子機構
Principal Investigator
畠中 寛
Project Period (FY)
1990
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Osaka University
Develpment of the Enzyme Immunoassay System for the Substances Related to the Pathogenesis of Alzheimer's Disease
Principal Investigator
Principal Investigator
HAYASHI Kyozo
Project Period (FY)
1990 – 1991
Research Category
Grant-in-Aid for Developmental Scientific Research (B)
Research Field
Neurology
Research Institution
Gifu Pharmaceutical University
Polymorphism of oligosaccharide structure in glycoconjugaates
Principal Investigator
TAKAHASHI Noriko
Project Period (FY)
1989 – 1991
Research Category
Grant-in-Aid for Co-operative Research (A)
Research Field
Pathological medical chemistry
Research Institution
Nagoya City University College of Nursing
ニューロン・グリア間認識の分子機構
Principal Investigator
御子柴 克彦
Project Period (FY)
1989
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Osaka University
Biochemical Studies on the Molecular Mechanism of Neurotransmission, Centered on Nicotinic Acetylcholine Receptor (nAChR)
Principal Investigator
Principal Investigator
HAYASHI Kyozo
Project Period (FY)
1988 – 1989
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Neurology
Research Institution
Gifu Pharmaceutical University
Development of the Enzyme Immunoassay Systems for the Substances Involved in the Cause of Alzheimer's Disease
Principal Investigator
Principal Investigator
HAYASHI Kyozo
Project Period (FY)
1988 – 1989
Research Category
Grant-in-Aid for Developmental Scientific Research
Research Field
Neurology
Research Institution
Gifu Pharmaceutical University
アセチルコリン受容体の機能発現に関する化学的研究
Principal Investigator
Principal Investigator
林 恭三
Project Period (FY)
1987
Research Category
Grant-in-Aid for Special Project Research
Research Institution
Gifu Pharmaceutical University
神経成長因子(NGF)合成促進薬物の抗痴呆薬としての応用・開発する研究
Principal Investigator
古川 昭栄
Project Period (FY)
1987 – 1988
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Neurology
Research Institution
National Center of Neurology and Psychiatry
細胞膜とその機能発現
Principal Investigator
山本 尚三
Project Period (FY)
1986
Research Category
Grant-in-Aid for Special Project Research
Research Institution
The University of Tokushima
神経成長促進因子の生成と存在様式に関する生化学的研究
Principal Investigator
Principal Investigator
林 恭三
Project Period (FY)
1986
Research Category
Grant-in-Aid for Special Project Research
Research Institution
Gifu Pharmaceutical University
ニューロン・グリア間認識の分子機構
Principal Investigator
御子柴 克彦
Project Period (FY)
1986 – 1988
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Osaka University
Biochemical Studies on the Mechanism of Neurotransmission--- Principally Structure-Function Relationship of Nicotinic Acetylcholine Receptor ---
Principal Investigator
Principal Investigator
HAYASHI Kyozo
Project Period (FY)
1986 – 1987
Research Category
Grant-in-Aid for General Scientific Research (A)
Research Field
Biological pharmacy
Research Institution
Gifu Pharmaceutical University
# of Projects (Dsc)
# of Projects (Asc)
1.
FURUKAWA Shoei
(90159129)
# of Collaborated Projects :
10results
# of Collaborated Products :
0results
2.
FURUKAWA Yoshiko
(20219108)
# of Collaborated Projects :
5results
# of Collaborated Products :
0results
3.
NOMOTO Hiroshi
(80164747)
# of Collaborated Projects :
4results
# of Collaborated Products :
0results
4.
KOHNO Michiaki
(00027335)
# of Collaborated Projects :
4results
# of Collaborated Products :
0results
5.
田中 亮
(90094383)
# of Collaborated Projects :
4results
# of Collaborated Products :
0results
6.
HIRANO Kazuyuki
(90057365)
# of Collaborated Projects :
3results
# of Collaborated Products :
0results
7.
SATO Masahiro
(00240945)
# of Collaborated Projects :
3results
# of Collaborated Products :
0results
8.
MORI Kazutoshi
(70182194)
# of Collaborated Projects :
3results
# of Collaborated Products :
0results
9.
NISHITANI Hiroshi
(70087287)
# of Collaborated Projects :
3results
# of Collaborated Products :
0results
10.
畠中 寛
(60208519)
# of Collaborated Projects :
3results
# of Collaborated Products :
0results
11.
花岡 和則
(40189577)
# of Collaborated Projects :
3results
# of Collaborated Products :
0results
12.
三木 直正
(40094445)
# of Collaborated Projects :
3results
# of Collaborated Products :
0results
13.
ADACHI Tetsuo
(40137063)
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
14.
HIRATANI Hajime
(60094083)
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
15.
池田 潔
(50001053)
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
16.
御子柴 克彦
(30051840)
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
17.
TAKAHASHI Noriko
(90079989)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
18.
KANNAGI Reiji
(80161389)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
19.
ISHIHARA Hideko
(90080192)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
20.
NAKASHIMA Izumi
(40022826)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
21.
ARATA Yoji
(40011499)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
22.
NAKAMURA Nobuyuki
(90198226)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
23.
FUJII Nobutaka
(60109014)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
24.
IIDA Akira
(40202816)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
25.
TAMAMURA Hirokazu
(80217182)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
26.
TAKIGAWA Masahiro
(80115873)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
27.
植村 慶一
(90049792)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
28.
山本 尚三
(50025607)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
29.
室田 誠逸
(50072989)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
30.
水上 茂樹
(90037325)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
31.
松田 佳子
(40035449)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
32.
藤多 哲朗
(40027024)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
33.
西川 徹
(00198441)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
34.
NAGAOKA Akinobu
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
35.
FUJIMOTO Masafumi
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
36.
NAKAZATO Hiroshi
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
37.
舩越 奨
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
38.
太田 光煕
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
39.
辻本 雅文
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
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