YAMAMOTO Shozou 山本尚三

… Alternative Names

Researcher Number	50025607
Other IDs
External Links
Affiliation *help	2002 – 2004 : 京都女子大学, 家政学部, 教授 1986 – 1998 : Tokushima University School of Medicine Professor and four other memebers., 医学部, 教授 1988 : 日本医科大学, 講師 1988 : 日本眞空技術, 部長 1986 : 徳島大, 医学部, 教授 1985 : 徳島大学, 医, 教授
Review Section/Research Field	Principal Investigator General medical chemistry / Pathological medical chemistry / Functional biochemistry Except Principal Investigator Pathological medical chemistry / 応用薬理学・医療系薬学 / General pharmacology / Circulatory organs internal medicine / 内分泌・代謝学 / Biological pharmacy / Otorhinolaryngology / Nuclear engineering
Keywords	Principal Investigator プロスタグランジン / アラキドン酸 / Arachidonic acid / リポキシゲナーゼ / シクロオキシゲナーゼ / Lipoxygenase / Cyclooxygenase / Prostaglandin / 生理活性物質 / 骨芽細胞 … More Except Principal Investigator 微小循環 / プロスタグランジン / リポキシゲナーゼ / 臓器虚血 / 臓器血流 / ロイコトリエン / 血管攣縮 / 心筋虚血 / アラキドン酸カスケード / 血栓形成 / 炎症 / prostaglandin / 血液凝固線溶因子 / レセプター / 心筋保護 / Thromboxane A_2 / シクロオキシゲナーゼ / 11-dehydro-thromboxane B_2 / 血管内視鏡 / 測定法 / カルシウムイオン / トロンボキサン / プロスタサイクリン / microalbuminuria / フリーラジカル / アラキドン酸 / Microangiopathy / ATPase活性 / 11-dehydro-TXB_2 / arachidonic acid / カルシウム / αーリノレン酸 / PAF / リポキシゲナ-ゼ / leukotriene / 6,15-diketo-13,14 dihydro PGF_1α / microangiopathy / leukotriene【C_4】 / リン脂質分解 / 酵素免疫測定法 / カルシウムチャンネル / cyclooxygenase / GC / 過収縮壊死 / Prostaglandin / Elimination of disturbing substances for assay / leukotriene【B_4】 / 再灌流障害 / leukotriens / オ-プン体 / 11ーDHーTXB_2 / 12-Lipoxygenase / Measurement / アラキドン酸代謝 / Assay for 11-dehydro-Thromboxane <B_2> / signal transduction / thromboxane / 妊娠中毒症 / LTB_4 / 培養心筋細胞 / αリノレン酸 / カルシウム動員 / TーD反応 / prostaglandins / leukotriene (LT) / 補聴器適合評価器機 / 細胞情報伝達 / leukotriene【D_4】 / inflammation / 血小板活性化因子 / トロンボキサンA_2 / 11ーデヒドローTXB_2 / Prostacyclin / 放射免疫測定法 / 環状イオン源 / ホスホリパーゼA_2 / 糖尿病血管合併症 / 糖尿病性血管合併症 / 12-lipoxygenase / 線溶活性 / Immunoaffinity-columu / arachidonic acid metabolism / レセプタ- / 生合成 / ホスホリパーゼ A_2 / 培養心筋 / 2,3ージノールーTXB_2 / 2, 3-dinor-6-keto-prostaglandin F_1alpha / Hypertension / MS / Diabetes mellitus / Isozyme / 11beta-PGF_<2alpha> / 2,3-dinor 6-keto PGF_1α / 抗体固相化カラム / ミトコンドリア / トロンボキサン(TXA_2) / Platelet / receptor / Inflammation / イムノアッセイ / pH / 8-isoprostane / 補聴器適合検査 / 2,3-dinor-b-keto PGF_1α / ホスホリパーゼC / 糖尿病 / 6,15-diketo-13,14dehydro PGF_1α / 6-keto-PG【F_(1α)】 / 2,3-ジノル-6-ケト-PGF1α / 病態 / A device for evaluating fitness of a hearing aid / シクロオキシゲナーゼ-2 / 固定化抗体カラム / Diabetic angiopathy / 血小板 / 単クローン抗体 / 尿 / Microalbuminuria / RIA法 / 副血行路 / ガスクロマトグラフィ質量分析法 / inhibitor / 高血圧 / alpha-linolenate / 11-dehydro-thromboxane【B_2】 / Diabetic nephropathy / speech hearing tests / phospholipase AィイD22ィエD2 / cyclooxygenase (COX) / ホスホリパーゼA2 / LC-MS / 前処理法 / 11-dehydro-TX【B_2】 / 再潅流 / EIA法 / Assay methods for prostaglandins / α-リノレン酸 / プロスタサイクリン(PGI_2) / コンパクトディスク / 線溶 / 11-デヒドロ-トロンボキサンB2 / 中性子源 / 語音聴力検査 / 11-デヒドロ-トロンボキサンB_2 / 糖尿病性腎症 / cycloxygenase-2 / 抗炎症薬 / 12-HETE / 抗体固定化カラム / リボキシゲナーゼ / Leukotriene / 過収縮 / GTP結合タンパク質 / Toxemia of pregnancy / 動物種差 / lipoxygenase / アイソザイム / 血漿 Less

Studies on the inhibitors of the catalytic activities and gene expressions of arachidonate oxygenasesPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Shozo
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Kyoto Women's University
Study on Cyclooxygenase Isozymes for Development of Anti-inflammatory Drugs
- Principal Investigator
  
  TANABE Tadashi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  National Cardiovascular Center Research Institute
Biosynthesis and metabolism of cannabimimetic anandamidePrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Shozo
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  The University of Tokushima
Biosynthesis and metabolism of anandamide as an endogenous ligand for cannabinoid receptorsPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Shozo
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Functional biochemistry
- Research Institution
  The University of Tokushima
Molecular biological studies on arachidonate oxygenase isozymesPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Shozo
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  The University of Tokushima
Estimation of platelet 12-lipoxygenase activity for persistent proteinuria as a risk factor of diabetic angiopathy in NIDDM patients.
- Principal Investigator
  
  TOHJIMA Toshio
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内分泌・代謝学
- Research Institution
  Juntendo University School of Medicine
Molecular pathophysiological studies on arachidonate lipoxygenasesPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Shozo
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Tokushima University School of Medicine
Development of cyclooxygenase-2 assay kits for new anti-inflammatory drugsPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Shozo
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General medical chemistry
- Research Institution
  The University of Tokushima
Arachibonate cascade and physiological
- Principal Investigator
  
  MIZUGAKI Michinao
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Tohoku University
Isozymes of cyclooxygenase and lipoxygenasePrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Shozo
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tokushima University
必須不飽和脂肪酸からの生体調節因子の生合成にかかわるリポキシゲナーゼの研究Principal Investigator
- Principal Investigator
  
  山本尚三
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokushima
Development of immunoaffinity purification and immunoassay of thromboxane and prostacyclin metabolitesPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Shozo
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tokushima University
必須不飽和脂肪酸からの生体調節因子の生合成にかかわるリポキシゲナーゼの研究Principal Investigator
- Principal Investigator
  
  山本尚三
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokushima
Molecular biological studies on cyclooxygenases and lipoxygenases dynamicsPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Shozo
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Tokushima University School of Medicine
Development by Gene Engineering of Kits for Screening the Enzymes of the Arachidonate CascadePrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Shozo
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  The University of Tokushima
Standardization and problems to measure prostanoids in the biological fluid.
- Principal Investigator
  
  ABE Keishi
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  TOHOKU UNIVERSITY
プロスタグランジンとその関連生理活性脂質の分子細胞学的作用機構Principal Investigator
- Principal Investigator
  
  山本尚三
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  The University of Tokushima
虚血による心筋細胞障害とその防御機構
- Principal Investigator
  
  中村元臣
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
Signal Transduction and Arachidonic Acid Metabolism in the Aid Drug of Development
- Principal Investigator
  
  ICHIKAWA Atsushi
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kyoto University
Study on the physiological and pathological dynamics of cyclooxygenase and lipoxygenase enzymesPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Shozo
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  General medical chemistry
- Research Institution
  The University of Tokushima
骨芽細胞シクロオキシゲナ-ゼ動態のcAMPによる調節Principal Investigator
- Principal Investigator
  
  山本尚三
- Project Period (FY)
  1988 – 1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokushima
臓器血流の制御とその病態
- Principal Investigator
  
  多田道彦
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Osaka University
虚血により心筋細胞障害とその防御機構
- Principal Investigator
  
  中村元臣
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
骨芽細胞シクロオキシゲナーゼ動態のcAMPによる調節Principal Investigator
- Principal Investigator
  
  山本尚三
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokushima
Development and automation of enzyme immunoassay of prostanoidsPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Shozo
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  General medical chemistry
- Research Institution
  Tokushima University
レセプター機構におけるカルシウムイオンの役割
- Principal Investigator
  
  野沢義則
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Gifu University
臓器血流の制御とその病態
- Principal Investigator
  
  多田道彦
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Osaka University
虚血による心筋細胞障害とその防御機構
- Principal Investigator
  
  中村元臣
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
14MeV強力中性子源の製作のための試験研究
- Principal Investigator
  
  磯矢影, 磯矢彰
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  Nuclear engineering
- Research Institution
  Tokai University
Studies on Mammalian LipoxygenasesPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Shozo
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Tokushima University
Development of assay method of novel metabolites of endogenous prostaglandins and its application
- Principal Investigator
  
  KATORI Makoto
- Project Period (FY)
  1987 – 1989
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  General pharmacology
- Research Institution
  Kitasato University School of Medicine
細胞膜とその機能発現Principal Investigator
- Principal Investigator
  
  山本尚三
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  The University of Tokushima
レセプター機構におけるカルシウムイオンの役割
- Principal Investigator
  
  野沢義則
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Gifu University
臓器血流の制御とその病態
- Principal Investigator
  
  TADA Michihiko
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Osaka University
Development of a device for evaluating fitness of a hearin aid
- Principal Investigator
  
  TANAKA Yoshisato
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Teikyo University
細胞膜とその機能発現Principal Investigator
- Principal Investigator
  
  山本尚三
- Project Period (FY)
  1985
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  The University of Tokushima
神経系におけるリポキシゲナーゼの局在と生理作用の研究Principal Investigator
- Principal Investigator
  
  山本尚三
- Project Period (FY)
  1985
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  The University of Tokushima
Biochemical srudies on the roles of prostaglandins, leukotrienes and PAf in pathogenesis
- Principal Investigator
  
  MUROTA Sei-itsu
- Project Period (FY)
  1985 – 1987
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tokyo Medical and Dental University
  Tokyo Metropolitan Institute of Gerontology
Development and application of a selective inhibitor of arachidonate 5-lipoxygenasePrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Shozo
- Project Period (FY)
  1984 – 1985
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  General medical chemistry
- Research Institution
  The University of Tokushima
Standarization of assay methods of endogenous prostaglandins and leukotrienes
- Principal Investigator
  
  KATORI Makoto
- Project Period (FY)
  1984 – 1986
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kitasato University School of Medicine

All 2005 2004 2002

All Journal Article Book

[Book] Mammalian lipoxygenases in The Eicosanoids(P.Curtis-Prior,ed.)2004
- Author(s)
  S.Yamamoto et al.
- Publisher
  John Wiley & Sons
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570113
[Book] The Eicosanoids(P.Curtic-Prior, ed.)(John Wiley & Sons)2004
- Author(s)
  S, Yamamoto
- Publisher
  Mammalian lipoxygenases
- Data Source
  KAKENHI-PROJECT-14570113
[Journal Article] Arachidonate 12-lipoxygenases with reference to their selective inhibitors2005
- Author(s)
  S.Yamamoto et al.
- Journal Title
  
  Biochem.Biophys.Res.Communs. 338
  
  Pages : 122-127
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570113
[Journal Article] Arachidonate 12-lipoxygenases with reference to their selictive inhibitors2005
- Author(s)
  S.Yamamoto et al.
- Journal Title
  
  Biochem. Biophys. Res. Communs. 338
  
  Pages : 122-127
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570113
[Journal Article] Mammalian lipoxygenases2004
- Author(s)
  S.Yamamoto et al.
- Journal Title
  
  The Eicosanoids (P.Curtis-Prior, ed.)(John Wiley & Sons)
  
  Pages : 53-59
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570113
[Journal Article] Affinities of mammalian arachidonate oxygenases for molecular oxygen2002
- Author(s)
  S.Yamamoto et al.
- Journal Title
  
  International Congress Series 1233
  
  Pages : 337-342
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570113

1. KATORI Makoto (50050365)

# of Collaborated Projects : 9results

# of Collaborated Products : 0results
2. MUROTA Seiitsu (50072989)

# of Collaborated Projects : 7results

# of Collaborated Products : 0results
3. HAYASHI Yoko (60035441)

# of Collaborated Projects : 7results

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4. TADA Michihiko (90093434)

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5. UEDA Natsuo (20193807)

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7. SUZUKI Hiroshi (80253194)

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8. 仁村康治 (50028320)

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33. INOUE Keizo (30072937)

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34. HARADA Yoshiteru (20050677)

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35. OMATA Ken (50194634)

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36. IMAI Kazuhiro (50012620)

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37. WAKU Keizo (90013854)

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38. YAMAMOTO Ikuo (50069746)

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39. KUDO Ichiro (30134612)

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40. TOHJIMA Toshio (70053048)

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45. INOUE Hiroyasu (40183743)

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46. MURAKAMI Makoto (60276607)

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47. YAMAMOTO Kei (30304504)

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48. TOMIOKA Hisao (20009632)

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49. TANAKA Yoshisato (70082013)

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50. OOTA Fumihiko (50088530)

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51. OKAMOTO Michinari (90053751)

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52. IMAI Hideo (30000285)

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53. 金子昇 (50075537)

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54. 岡本光弘 (90028613)

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55. 小沢高将 (80022771)

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56. 大村恒雄 (80029933)

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57. 田中亮 (90094383)

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58. 水上茂樹 (90037325)

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59. 松田佳子 (40035449)

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60. 林恭三 (00029935)

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61. 金澤知博 (90004762)

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62. 磯矢影 (80037134)

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63. 矢部栄二 (70056018)

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65. 北島一徳 (70038529)

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66. 高山一男 (20023690)

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67. SHIMIZU Yasuo (60015873)

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68. NAKANISHI Yasuko (50014725)

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69. MATSUMOTO Takashi

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70. YAMASHITA Kowa

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71. HAMANAKA Nobuyuki

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72. HIRAMATSU Makoto

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73. SAWADA Masahumi

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74. WENDEL Birgid

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75. NIGAM Santosh

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76. KUEHM Hartmut

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77. HIGUCHI Shohei

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78. MIYAMOTO Tsumoru

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79. PIOMELLI Daniele

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80. GERWICK William

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81. MARZO Vincenzo di

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82. ASHIDA Yasuko

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83. 磯矢彰

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84. VINCENZO Di.

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85. 鳥山稔

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YAMAMOTO Shozou 山本 尚三

山川 洋幸

中村 賢二

Research Projects

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Studies on the inhibitors of the catalytic activities and gene expressions of arachidonate oxygenasesPrincipal Investigator

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Biosynthesis and metabolism of cannabimimetic anandamidePrincipal Investigator

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Biosynthesis and metabolism of anandamide as an endogenous ligand for cannabinoid receptorsPrincipal Investigator

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Molecular biological studies on arachidonate oxygenase isozymesPrincipal Investigator

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Molecular pathophysiological studies on arachidonate lipoxygenasesPrincipal Investigator

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Development of cyclooxygenase-2 assay kits for new anti-inflammatory drugsPrincipal Investigator

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Isozymes of cyclooxygenase and lipoxygenasePrincipal Investigator

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必須不飽和脂肪酸からの生体調節因子の生合成にかかわるリポキシゲナーゼの研究Principal Investigator

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Development of immunoaffinity purification and immunoassay of thromboxane and prostacyclin metabolitesPrincipal Investigator

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必須不飽和脂肪酸からの生体調節因子の生合成にかかわるリポキシゲナーゼの研究Principal Investigator

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Molecular biological studies on cyclooxygenases and lipoxygenases dynamicsPrincipal Investigator

Principal Investigator

YAMAMOTO Shozou 山本尚三

山川洋幸

中村賢二