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YAMASHITA Hiroshi
山下 博
Researcher Number
00030841
Affiliation
*help
2002 : Kyushu Nutrition Welfare University, Professor, 食物栄養学部, 教授
2000 – 2001 : 産業医科大学, 医学部, 名誉教授
1996 – 2000 : 産業医大, 医学部, 教授
1986 – 2000 : University of Occupational and Environmental Health, School of Medicine Prof., 医学部, 教授
1987 – 1989 : 産業医科大学, 教授
Research Field
Except Principal Investigator
Environmental physiology (including Physical medicine and Nutritional physiology)
/
環境生理学(含体力医学･栄養生理学)
/
General physiology
/
Anesthesiology/Resuscitation studies
/
Neurophysiology and muscle physiology
Keywords
Except Principal Investigator
バゾプレッシン / 視床下部 / 視索上核 / オキシトシン / PACAP / 室傍核 / 神経内分泌 / 遺伝性多飲マウス / カルシウム画像解析 / 自律神経
…
More
/ supraoptic nucleus / 体温調節 / パッチクランプ / CCK-8 / ペプチド / 化学感受性ニューロン / バゾプレシン / adrenomedullin / Ca^<2+> imaging / mRNA / 飲水行動 / アドレノメデュリン / アドレノメデユリン / vasopressin / 非選択性陽イオンチャネル / ストレス / non-selective cation channels / PAMP / サイトカイン / 視床下部視索上核 / Oxytocin / プロスタグランディン / パッチクランプ法 / blood-brain barrier / direction-related neuron / 内在性生理活性物質 / オレキシン / neural transplantation / Anestetized cat and rat / Interferon / hypothalamo-pituitary-adrenal axis / AM遺伝子 / 自律神経系 / 脳スライス標本 / タイトジャンクション / Conscious rat / プロポフォール / グルカゴン / 脳神経 / チトクローム / 脳内移殖 / Non-spiking neurone / 水代謝の比較生理学 / 神経移植 / c-fos蛋白 / 中枢内神経回路 / ラジオイムノアッセイ / biologically active peptide / 水分代謝の比較生理学 / renal sympathetic nerve activity / Paraventricular nucleus / Neuropeptides / salivary gland / ILー1 / 脳脊髄液 / FGF / 病態生理 / autonomic nerve / 遺伝多飲マウス / 抗利尿効果 / voltage-dependent Ca^<2+> / NK細胞活性 / アドレノメデュリン遺伝子 / central nervous system / 体液・循環調節 / pathophysiology / Redox state / Inhibitory postsynaptic currents / 水分代謝と体温 / Caffeine / 非選択的陽イオン電流 / 視床下部温度感受性ニュ-ロン / 水分調節 / Comparative physiology / microdialysis / 分泌 / 飲水 / 神経分泌ニュ-ロン / Ryanodine Ca^<2+> stores / Orexin / 情報伝達 / CCK-octapeptide / thymus / C末端アミド化 / 静脈麻酔薬 / VIP / 滲透圧調節 / 摂食代謝調節 / 受容認識 / Water metabolism / receptor / Fibroblast Growth Factor / 水分代謝と循環 / Urocortin / 下垂体中葉 / 神経回路網 / Thermoregulation / ネコ・ラット急性実験 / 循環器疾患 / 覚醒ラット / Neurosecretion / 神経回路網の解析 / endothelial cells / tight junction / ニューロランシン / 血液脳関門 / circulation control / Brain slice preparation / 賢交感神経 / acidic fibroblast growth factor / Patch clamp / Ca^<2+>画像解析法 / アドレノメュリン / CCKー8 / Drinking / 免疫サイトカイン / cerebrospinal fluid / 細胞内Ca^<2+>濃度の画像解析 / 神経ペプチド / transgenic animal / 神経的制御 / ノックアウト動物 / 不斉合成 / 循環 / RT-PCR怯 / 降圧ペプチド / Environmental adaptation / Renal sympathetic nerve activity / グルココルチコイド / 胃からの求心性入力 / 松果体 / glucocorticoid receptor / GABA_B受容体 / 酸性線維芽細胞成長因子 / Inbred polydipsic mouse / 循環調節機構 / Vasopressin / Fos蛋白 / Endogenous Neurosubstances / Pars intermedia / Ca^<2+>電流 / hypothalamus / ANP / V2受容体遺伝子 / 循環調節 / drinking behavior / GABA / 生体内制御機構 / 循環調節因子 / 進化 / インターフェロン / nociceptice response / Prostaglandin E_2 / 化学的制御 / 視床下部・下垂体・副腎皮質系 / 脳腸ペプチド / ウロコルチン / laryngeal nerve / Water balance and circulation / IL-1 / Adrenomedullin / 有機酸 / 自律神経活動 / 酸化還元位 / 受容体 / learning behavior / 脳スライス実験 / DNA合成能 / Ca^<2+>画像解析 / Ryanodine感受性Ca^<2+>ストア / 情報行動 / Osmoregulation / knockout mouse / 生合成機構 / 抑制性シナプス電流 / 扁桃体内側核 / ホールセルパッチクランプ法 / 病態 / 視視策上核 / FP受容体 / 動脈硬化 / genetically polydipsic mice / 認知関連ニュ-ロン / Leptin / Supraoptic nucleus / 脳Na利尿ホルモン / EP受容体 / N)マウス / 海馬学習関連ニュ-ロン / アンギオテンシン / 予測制御 / AMシンポジウム / 水分代謝 / レプチン / ノンスパイキングニューロン / 学習 / hypothalamic neuronal histamine / adjuvant arthritis / ラットアジュバンド関節炎 / Food Intake / セロトニン / インビボマイクロダイアリーシス / 脳移植 / 血管内皮細胞 / RAMP-1,-2,-3 / 脳スライス / サイアミラル / Neural network / ニューロテンシン / feedforward control / ホールセルパッチクランプ / hypothalamic thermosensitive neuron / 生理活性ペプチド / Cytochromes / 視床下部温度ニュ-ロン / 血圧 / 胸腺 / Neurosecretory neuron / olfactory receptor neuron / コルチコステロン / In situ hybridization法 / エンドセリン / Interleukins / 抑制性シナプス後電位 / グルココルチコイド受容体 / 嗅細胞 / 本能行動 / 学習行動解析 / イオンチャネル / ラットアジュバント関節炎 / 視床下部神経分泌ヒスタミン / ボンベシン / バゾプレッシン遺伝子 / 脳腸ホルモン / 遺伝性多飲(STR / c-fos mRNA / Central control of water balance / 上喉頭神経 / 腎交感神経 / グルカブン / 免疫異常 / Whole-cell patch-clamp / 蝸牛有毛細胞 / cytokine / Substance P / Ryanodin感受性Ca^<2+>ストア / 味覚神経 / Triphosphoinositide (TPI) / paraventricular nucleus / 脳薄切標本 / TNF / 血管作動性ペプチド / 肝門脈IL-1βセンサ- / セロトニンEC細胞 / GABA_B receptors / 唾液腺 / stress / 探索医療 / プロスタグランディンE_2 / 膜電位依存性Ca^<2+>電流 / 心不全 / 環境適応 / グリア細胞 / chemosensitive neuron / 化学感受性ニュ-ロン / モノクローナル抗体 / inbred polydipsic mice / 遺伝子解析 / 侵害受容行動 / 海馬方向選択ニューロン / トランスジェニック動物 / Prostaglandins / Water balance and body temperature / 中枢性体液調節
Less
Research Projects
(
17
results)
Co-Researchers
(
54
People)
Project Start Year(Newest)
Project Start Year(Oldest)
The localization and physiological role of adrenomedullin and related-peptides in the central nervous system
Principal Investigator
Principal Investigator
UETA Yoichi
, 山下 博
Project Period (FY)
2002
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
University of Occupational and Environmental Health, Japan
Role of Cardiovascular-related Peptides in the Brain : Genetic, Molecular Biological, Morphological and Physiological Aspects.
Principal Investigator
Principal Investigator
YAMASHITA Hiroshi
Project Period (FY)
1998 – 1999
Research Category
Grant-in-Aid for Scientific Research (B).
Research Field
Environmental physiology (including Physical medicine and Nutritional physiology)
Research Institution
University of Occupational and Environmental Health
The study of physiological and pathophysiological roles of adrenomedullin and related peptides.
Principal Investigator
ETO Tanenao
Project Period (FY)
1998 – 2002
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Miyazaki Medical College
Molecular and Cellular Biology in Mechanism of Body Fluid Homeostasis (Analysis of Inter- and Intra-Cellular Signalling in the Neurosecretory Cells)
Principal Investigator
Principal Investigator
YAMASHITA Hiroshi
Project Period (FY)
1998 – 1999
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Environmental physiology (including Physical medicine and Nutritional physiology)
Research Institution
University of Occupational and Environmental Health
免疫サイトカイン・神経ペプチド麻酔関連薬の視床下部神経内分泌細胞への影響
Principal Investigator
井上 義崇
Project Period (FY)
1996
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Anesthesiology/Resuscitation studies
Research Institution
University of Occupational and Environmental Health, Japan
Analysis of the mechanism of immune signal transduction to hypothalamic neuroendocrine cells
Principal Investigator
Principal Investigator
YAMASHITA Hiroshi
Project Period (FY)
1996 – 1997
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Environmental physiology (including Physical medicine and Nutritional physiology)
Research Institution
University of Occupational and Environmental Health
The role of water metabolism on the environmental adaptation
Principal Investigator
MORIMOTO Taketoshi
Project Period (FY)
1995 – 1996
Research Category
Grant-in-Aid for Scientific Research (A)
Research Field
Environmental physiology (including Physical medicine and Nutritional physiology)
Research Institution
Kyoto Prefectural University of Medicine
Neuroendocrine and immune system in genetically polydipsic mice and development of animal model in response to environmental stress
Principal Investigator
Principal Investigator
YAMASHITA Hiroshi
Project Period (FY)
1995 – 1997
Research Category
Grant-in-Aid for Scientific Research (A)
Research Field
Environmental physiology (including Physical medicine and Nutritional physiology)
Research Institution
University of Occupational and Environmental Health
Analysis with Ca2+ imaging and membrane potential measurement in neuroendocrine cells
Principal Investigator
SHIBUYA Izumi
Project Period (FY)
1995 – 1996
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
General physiology
Research Institution
University of Occupational and Environmental Health
バゾプレッシン・オキシトシンによる生体調節機序の解明-分子生物学・形態学・薬理学及び生理学的アプローチ-
Principal Investigator
Principal Investigator
山下 博
Project Period (FY)
1995 – 1996
Research Category
Grant-in-Aid for international Scientific Research
Research Institution
University of Occupational and Environmental Health, Japan
Role of immunocytokine on the neuroendocrine sysytem
Principal Investigator
Principal Investigator
YAMASHITA Hiroshi
Project Period (FY)
1992 – 1994
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
環境生理学(含体力医学･栄養生理学)
Research Institution
University of Occupational and Environmental Health
Central mechanisms of drinking behavior in inbred polydipsic mice : molecular and physiological analysis
Principal Investigator
Principal Investigator
YAMASHITA Hiroshi
Project Period (FY)
1991 – 1992
Research Category
Grant-in-Aid for international Scientific Research
Research Institution
University of Occupational and Environmental Health
Roles of Neuropeptides on Central Regulation of Water Balance and Autonomic Nervous System
Principal Investigator
Principal Investigator
YAMASHITA Hiroshi
Project Period (FY)
1988 – 1990
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
環境生理学(含体力医学･栄養生理学)
Research Institution
University of Occupational and Environmental Health, Japan
生体調節系における脳腸ペプチドの役割
Principal Investigator
KANNO Tomio
Project Period (FY)
1987
Research Category
Grant-in-Aid for Co-operative Research (B)
Research Field
General physiology
Research Institution
Hokkaido University
Neuronal and chemical control of emotical behavior
Principal Investigator
OOMURA Yutaka
Project Period (FY)
1987 – 1989
Research Category
Grant-in-Aid for Co-operative Research (A)
Research Field
Neurophysiology and muscle physiology
Research Institution
Kyushu University
New Endogenous Substances Controlling Different Homeostatic Functions.
Principal Investigator
HORI Tetsuro
Project Period (FY)
1987 – 1988
Research Category
Grant-in-Aid for Co-operative Research (A)
Research Field
環境生理学(含体力医学･栄養生理学)
Research Institution
Saga Medical School
Paracrine secretion; its function, morphology and concept
Principal Investigator
KANNO Tomio
Project Period (FY)
1985 – 1986
Research Category
Grant-in-Aid for Co-operative Research (A)
Research Field
General physiology
Research Institution
Hokkaido University
# of Projects (Dsc)
# of Projects (Asc)
1.
UETA Yoichi
(10232745)
# of Collaborated Projects :
10results
# of Collaborated Products :
0results
2.
SHIBUYA Izumi
(50162649)
# of Collaborated Projects :
7results
# of Collaborated Products :
0results
3.
INENAGA Kiyotoshi
(90131903)
# of Collaborated Projects :
6results
# of Collaborated Products :
0results
4.
KANNAN Hiroshi
(00049058)
# of Collaborated Projects :
5results
# of Collaborated Products :
0results
5.
KAWATA Mitsuhiro
(60112512)
# of Collaborated Projects :
4results
# of Collaborated Products :
0results
6.
HORI Tetsuro
(00022814)
# of Collaborated Projects :
3results
# of Collaborated Products :
0results
7.
KANNO Tomio
(50009982)
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
8.
OTSUKA Masanori
(60013801)
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
9.
HISADA Mituhiko
(70000768)
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
10.
YANAIHARA Noboru
(80046250)
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
11.
KABASHIMA Narutoshi
(80279322)
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
12.
KANGAWA Kenji
(00112417)
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
13.
OOMURA Yutaka
(30019517)
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
14.
DREIFUSS J.J
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
15.
KOIZUMI Kiyo
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
16.
NAGATOMO Toshihisa
(50258604)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
17.
MORIMOTO Taketoshi
(30079694)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
18.
TAKEI Yoshio
(10129249)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
19.
SHIRAKI Keizo
(00035453)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
20.
YAMASHITA Uki
(00028680)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
21.
ETO Tanenao
(10038854)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
22.
MINAMINO Naoto
(50124839)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
23.
NAKAO Kazuwa
(00172263)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
24.
FUJITA Toshiro
(10114125)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
25.
KITAMURA Kazuo
(50204912)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
26.
NOGUCHI Jun
(00330978)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
27.
SERINO Ryota
(00309957)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
28.
YANAGISAWA Keiji
(20064363)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
29.
ONODA Norihiko
(60106903)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
30.
ONO Taketoshi
(50019577)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
31.
NIIJIMA Akira
(20018287)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
32.
NAGASAKA Tetsuo
(80023646)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
33.
NAKAYAMA Teruo
(80022763)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
34.
SANO Yutaka
(00079683)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
35.
OSAKA Toshimasa
(30152101)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
36.
井上 義崇
(60279346)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
37.
重松 昭生
(30037428)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
38.
小林 繁
(00018342)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
39.
細見 弘
(70030864)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
40.
根来 英雄
(90018903)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
41.
大磯 ユタカ
(40203707)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
42.
MASSAKO KADE
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
43.
KIYOMI KOIZU
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
44.
KOIZUMI Kiyomi
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
45.
KADEKARO Masako
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
46.
KADEKARO Mas
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
47.
TRIBOLLET El
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
48.
KOW Lee Ming
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
49.
VALE Wylie
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
50.
TRIBOLLET E.
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
51.
KOIZUMI K.
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
52.
PFAFF D.W.
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
53.
KOIZUMI K
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
54.
PFAFF D.W
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
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