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Yamashita Hiroshi
山下 博
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Alternative Names
YAMASHITA Hiroshi 山下 博
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Researcher Number
00030841
Affiliation (Current)
2022: 産業医科大学, 名誉教授、学長等, 名誉教授
Affiliation (based on the past Project Information)
*help
2002: Kyushu Nutrition Welfare University, Professor, 食物栄養学部, 教授
2000 – 2001: 産業医科大学, 医学部, 名誉教授
1986 – 2000: University of Occupational and Environmental Health, School of Medicine Prof., 医学部, 教授
1987 – 1989: 産業医科大学, 教授
Review Section/Research Field
Principal Investigator
Environmental physiology (including Physical medicine and Nutritional physiology)
/
環境生理学(含体力医学･栄養生理学)
Except Principal Investigator
General physiology
/
Biological Sciences
/
Anesthesiology/Resuscitation studies
/
Environmental physiology (including Physical medicine and Nutritional physiology)
/
Neurophysiology and muscle physiology
/
環境生理学(含体力医学･栄養生理学)
Keywords
Principal Investigator
バゾプレッシン / オキシトシン / 遺伝性多飲マウス / 視床下部 / 視索上核 / 室傍核 / パッチクランプ法 / カルシウム画像解析 / vasopressin / supraoptic nucleus
…
More
/ バゾプレシン / PACAP / 遺伝子解析 / In situ hybridization法 / 飲水行動 / Inbred polydipsic mouse / drinking behavior / hypothalamus / サイトカイン / 自律神経 / インビボマイクロダイアリーシス / ラットアジュバンド関節炎 / 視床下部・下垂体・副腎皮質系 / 遺伝多飲マウス / 免疫異常 / ラットアジュバント関節炎 / c-fos蛋白 / mRNA / ストレス / cytokine / renal sympathetic nerve activity / microdialysis / paraventricular nucleus / inbred polydipsic mice / adjuvant arthritis / hypothalamo-pituitary-adrenal axis / 唾液腺 / 味覚神経 / 侵害受容行動 / 胸腺 / グルココルチコイド受容体 / 学習行動解析 / V2受容体遺伝子 / DNA合成能 / NK細胞活性 / 抗利尿効果 / 上喉頭神経 / 遺伝性多飲(STR / N)マウス / c-fos mRNA / グルココルチコイド / バゾプレッシン遺伝子 / 脳スライス標本 / 細胞内Ca^<2+>濃度の画像解析 / genetically polydipsic mice / salivary gland / laryngeal nerve / nociceptice response / thymus / glucocorticoid receptor / learning behavior / プロスタグランディン / ホールセルパッチクランプ / 下垂体中葉 / 膜電位依存性Ca^<2+>電流 / 非選択的陽イオン電流 / 抑制性シナプス電流 / 視床下部視索上核 / ホールセルパッチクランプ法 / Ca^<2+>画像解析法 / 抑制性シナプス後電位 / 非選択性陽イオンチャネル / EP受容体 / FP受容体 / パッチクランプ / Prostaglandins / Whole-cell patch-clamp / Ca^<2+> imaging / Pars intermedia / voltage-dependent Ca^<2+> / non-selective cation channels / Inhibitory postsynaptic currents / アドレノメュリン / オレキシン / レプチン / ウロコルチン / アドレノメデユリン / 循環 / ペプチド / イオンチャネル / 学習 / Vasopressin / Adrenomedullin / Oxytocin / Orexin / Leptin / Urocortin / 神経内分泌 / Neurosecretion / Paraventricular nucleus / Supraoptic nucleus / 脳薄切標本 / 神経ペプチド / 神経分泌ニュ-ロン / ネコ・ラット急性実験 / 神経回路網 / 覚醒ラット / 賢交感神経 / 腎交感神経 / 体液・循環調節 / 神経回路網の解析 / 自律神経活動 / 脳スライス実験 / 胃からの求心性入力 / エンドセリン / セロトニン / 水分調節 / 自律神経系 / 中枢内神経回路 / 脳スライス / 化学感受性ニューロン / Brain slice preparation / Neuropeptides / Neurosecretory neuron / Anestetized cat and rat / Neural network / Conscious rat / Renal sympathetic nerve activity
…
More
Except Principal Investigator
神経内分泌 / PACAP / バゾプレッシン / 視床下部 / 視索上核 / アドレノメデュリン / PAMP / adrenomedullin / 自律神経 / CCK-8 / 体温調節 / 静脈麻酔薬 / プロポフォール / サイアミラル / GABA / Ca^<2+>電流 / 脳腸ペプチド / 脳腸ホルモン / 進化 / 分泌 / 受容認識 / 情報伝達 / 病態 / 水分代謝 / 環境適応 / 飲水 / 中枢性体液調節 / 水分代謝の比較生理学 / 水分代謝と体温 / 水分代謝と循環 / 予測制御 / 飲水行動 / 水代謝の比較生理学 / Water metabolism / Environmental adaptation / Drinking / Central control of water balance / Comparative physiology / Water balance and body temperature / Water balance and circulation / feedforward control / Ca^<2+>画像解析 / パッチクランプ / 視床下部視索上核 / GABA_B受容体 / プロスタグランディンE_2 / Caffeine / Ryanodin感受性Ca^<2+>ストア / 非選択性陽イオンチャネル / Ryanodine感受性Ca^<2+>ストア / カルシウム画像解析 / プロスタグランディン / サイトカイン / Ca^<2+> imaging / Patch clamp / supraoptic nucleus / GABA_B receptors / Prostaglandin E_2 / Ryanodine Ca^<2+> stores / non-selective cation channels / 生理活性ペプチド / 循環調節 / 病態生理 / 受容体 / トランスジェニック動物 / ノックアウト動物 / 循環器疾患 / モノクローナル抗体 / 探索医療 / 降圧ペプチド / 心不全 / 動脈硬化 / アドレノメデュリン遺伝子 / 循環調節機構 / 生体内制御機構 / 生合成機構 / AM遺伝子 / AMシンポジウム / ラジオイムノアッセイ / 循環調節因子 / 血管作動性ペプチド / C末端アミド化 / biologically active peptide / circulation control / pathophysiology / receptor / transgenic animal / knockout mouse / アドレノメデユリン / 血液脳関門 / 血管内皮細胞 / 脳神経 / 脳脊髄液 / タイトジャンクション / ストレス / グリア細胞 / mRNA / RT-PCR怯 / RAMP-1,-2,-3 / オキシトシン / Fos蛋白 / 血圧 / 室傍核 / blood-brain barrier / endothelial cells / central nervous system / cerebrospinal fluid / tight junction / stress / チトクローム / 酸化還元位 / ノンスパイキングニューロン / 視視策上核 / 蝸牛有毛細胞 / 扁桃体内側核 / 松果体 / Cytochromes / Redox state / CCK-octapeptide / Non-spiking neurone / Substance P / Oxytocin / Triphosphoinositide (TPI) / 化学感受性ニュ-ロン / 認知関連ニュ-ロン / 神経移植 / 嗅細胞 / 視床下部温度感受性ニュ-ロン / 酸性線維芽細胞成長因子 / 視床下部神経分泌ヒスタミン / 海馬学習関連ニュ-ロン / 視床下部温度ニュ-ロン / 肝門脈IL-1βセンサ- / 化学感受性ニューロン / 海馬方向選択ニューロン / 脳Na利尿ホルモン / セロトニンEC細胞 / 脳移植 / 免疫サイトカイン / 不斉合成 / 情報行動 / 神経的制御 / 化学的制御 / ペプチド / 有機酸 / 本能行動 / 脳内移殖 / chemosensitive neuron / direction-related neuron / neural transplantation / olfactory receptor neuron / hypothalamic thermosensitive neuron / autonomic nerve / acidic fibroblast growth factor / hypothalamic neuronal histamine / 滲透圧調節 / 摂食代謝調節 / 内在性生理活性物質 / FGF / インターフェロン / IL-1 / アンギオテンシン / ANP / コルチコステロン / グルカゴン / ニューロテンシン / VIP / TNF / ボンベシン / グルカブン / ニューロランシン / ILー1 / CCKー8 / Thermoregulation / Osmoregulation / Food Intake / Endogenous Neurosubstances / Fibroblast Growth Factor / Interferon / Interleukins
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Research Projects
(
17
results)
Co-Researchers
(
54
People)
Project Start Year (Newest)
Project Start Year (Oldest)
The localization and physiological role of adrenomedullin and related-peptides in the central nervous system
Principal Investigator
Principal Investigator
UETA Yoichi
, 山下 博
Project Period (FY)
2002
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Review Section
Biological Sciences
Research Institution
University of Occupational and Environmental Health, Japan
Role of Cardiovascular-related Peptides in the Brain : Genetic, Molecular Biological, Morphological and Physiological Aspects.
Principal Investigator
Principal Investigator
YAMASHITA Hiroshi
Project Period (FY)
1998 – 1999
Research Category
Grant-in-Aid for Scientific Research (B).
Research Field
Environmental physiology (including Physical medicine and Nutritional physiology)
Research Institution
University of Occupational and Environmental Health
The study of physiological and pathophysiological roles of adrenomedullin and related peptides.
Principal Investigator
ETO Tanenao
Project Period (FY)
1998 – 2002
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Review Section
Biological Sciences
Research Institution
Miyazaki Medical College
Molecular and Cellular Biology in Mechanism of Body Fluid Homeostasis (Analysis of Inter- and Intra-Cellular Signalling in the Neurosecretory Cells)
Principal Investigator
Principal Investigator
YAMASHITA Hiroshi
Project Period (FY)
1998 – 1999
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Environmental physiology (including Physical medicine and Nutritional physiology)
Research Institution
University of Occupational and Environmental Health
免疫サイトカイン・神経ペプチド麻酔関連薬の視床下部神経内分泌細胞への影響
Principal Investigator
井上 義崇
Project Period (FY)
1996
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Anesthesiology/Resuscitation studies
Research Institution
University of Occupational and Environmental Health, Japan
Analysis of the mechanism of immune signal transduction to hypothalamic neuroendocrine cells
Principal Investigator
Principal Investigator
YAMASHITA Hiroshi
Project Period (FY)
1996 – 1997
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Environmental physiology (including Physical medicine and Nutritional physiology)
Research Institution
University of Occupational and Environmental Health
バゾプレッシン・オキシトシンによる生体調節機序の解明-分子生物学・形態学・薬理学及び生理学的アプローチ-
Principal Investigator
Principal Investigator
山下 博
Project Period (FY)
1995 – 1996
Research Category
Grant-in-Aid for international Scientific Research
Research Institution
University of Occupational and Environmental Health, Japan
The role of water metabolism on the environmental adaptation
Principal Investigator
MORIMOTO Taketoshi
Project Period (FY)
1995 – 1996
Research Category
Grant-in-Aid for Scientific Research (A)
Research Field
Environmental physiology (including Physical medicine and Nutritional physiology)
Research Institution
Kyoto Prefectural University of Medicine
Neuroendocrine and immune system in genetically polydipsic mice and development of animal model in response to environmental stress
Principal Investigator
Principal Investigator
YAMASHITA Hiroshi
Project Period (FY)
1995 – 1997
Research Category
Grant-in-Aid for Scientific Research (A)
Research Field
Environmental physiology (including Physical medicine and Nutritional physiology)
Research Institution
University of Occupational and Environmental Health
Analysis with Ca2+ imaging and membrane potential measurement in neuroendocrine cells
Principal Investigator
SHIBUYA Izumi
Project Period (FY)
1995 – 1996
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
General physiology
Research Institution
University of Occupational and Environmental Health
Role of immunocytokine on the neuroendocrine sysytem
Principal Investigator
Principal Investigator
YAMASHITA Hiroshi
Project Period (FY)
1992 – 1994
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
環境生理学(含体力医学･栄養生理学)
Research Institution
University of Occupational and Environmental Health
Central mechanisms of drinking behavior in inbred polydipsic mice : molecular and physiological analysis
Principal Investigator
Principal Investigator
YAMASHITA Hiroshi
Project Period (FY)
1991 – 1992
Research Category
Grant-in-Aid for international Scientific Research
Research Institution
University of Occupational and Environmental Health
Roles of Neuropeptides on Central Regulation of Water Balance and Autonomic Nervous System
Principal Investigator
Principal Investigator
YAMASHITA Hiroshi
Project Period (FY)
1988 – 1990
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
環境生理学(含体力医学･栄養生理学)
Research Institution
University of Occupational and Environmental Health, Japan
生体調節系における脳腸ペプチドの役割
Principal Investigator
KANNO Tomio
Project Period (FY)
1987
Research Category
Grant-in-Aid for Co-operative Research (B)
Research Field
General physiology
Research Institution
Hokkaido University
Neuronal and chemical control of emotical behavior
Principal Investigator
OOMURA Yutaka
Project Period (FY)
1987 – 1989
Research Category
Grant-in-Aid for Co-operative Research (A)
Research Field
Neurophysiology and muscle physiology
Research Institution
Kyushu University
New Endogenous Substances Controlling Different Homeostatic Functions.
Principal Investigator
HORI Tetsuro
Project Period (FY)
1987 – 1988
Research Category
Grant-in-Aid for Co-operative Research (A)
Research Field
環境生理学(含体力医学･栄養生理学)
Research Institution
Saga Medical School
Paracrine secretion; its function, morphology and concept
Principal Investigator
KANNO Tomio
Project Period (FY)
1985 – 1986
Research Category
Grant-in-Aid for Co-operative Research (A)
Research Field
General physiology
Research Institution
Hokkaido University
# of Projects (Dsc)
# of Projects (Asc)
1.
UETA Yoichi
(10232745)
# of Collaborated Projects:
10 results
# of Collaborated Products:
0 results
2.
SHIBUYA Izumi
(50162649)
# of Collaborated Projects:
7 results
# of Collaborated Products:
0 results
3.
INENAGA Kiyotoshi
(90131903)
# of Collaborated Projects:
6 results
# of Collaborated Products:
0 results
4.
KANNAN Hiroshi
(00049058)
# of Collaborated Projects:
5 results
# of Collaborated Products:
0 results
5.
KAWATA Mitsuhiro
(60112512)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
6.
HORI Tetsuro
(00022814)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
7.
KANNO Tomio
(50009982)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
8.
OTSUKA Masanori
(60013801)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
9.
HISADA Mituhiko
(70000768)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
10.
YANAIHARA Noboru
(80046250)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
11.
KABASHIMA Narutoshi
(80279322)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
12.
KANGAWA Kenji
(00112417)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
13.
OOMURA Yutaka
(30019517)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
14.
DREIFUSS J.J
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
15.
KOIZUMI Kiyo
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
16.
NAGATOMO Toshihisa
(50258604)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
17.
MORIMOTO Taketoshi
(30079694)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
18.
TAKEI Yoshio
(10129249)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
19.
SHIRAKI Keizo
(00035453)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
20.
YAMASHITA Uki
(00028680)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
21.
ETO Tanenao
(10038854)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
22.
MINAMINO Naoto
(50124839)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
23.
NAKAO Kazuwa
(00172263)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
24.
FUJITA Toshiro
(10114125)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
25.
KITAMURA Kazuo
(50204912)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
26.
NOGUCHI Jun
(00330978)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
27.
SERINO Ryota
(00309957)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
28.
YANAGISAWA Keiji
(20064363)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
29.
ONODA Norihiko
(60106903)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
30.
ONO Taketoshi
(50019577)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
31.
NIIJIMA Akira
(20018287)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
32.
NAGASAKA Tetsuo
(80023646)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
33.
NAKAYAMA Teruo
(80022763)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
34.
SANO Yutaka
(00079683)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
35.
OSAKA Toshimasa
(30152101)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
36.
井上 義崇
(60279346)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
37.
重松 昭生
(30037428)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
38.
小林 繁
(00018342)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
39.
細見 弘
(70030864)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
40.
根来 英雄
(90018903)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
41.
大磯 ユタカ
(40203707)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
42.
TRIBOLLET E.
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
43.
KOIZUMI K.
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
44.
PFAFF D.W.
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
45.
KOIZUMI K
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
46.
PFAFF D.W
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
47.
MASSAKO KADE
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
48.
KIYOMI KOIZU
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
49.
KOIZUMI Kiyomi
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
50.
KADEKARO Masako
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
51.
KADEKARO Mas
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
52.
TRIBOLLET El
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
53.
KOW Lee Ming
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
54.
VALE Wylie
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
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