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Yamashita Hiroshi  山下 博

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YAMASHITA Hiroshi  山下 博

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Researcher Number 00030841
Affiliation (Current) 2022: 産業医科大学, 名誉教授、学長等, 名誉教授
Affiliation (based on the past Project Information) *help 2002: Kyushu Nutrition Welfare University, Professor, 食物栄養学部, 教授
2000 – 2001: 産業医科大学, 医学部, 名誉教授
1986 – 2000: University of Occupational and Environmental Health, School of Medicine Prof., 医学部, 教授
1987 – 1989: 産業医科大学, 教授
Review Section/Research Field
Principal Investigator
Environmental physiology (including Physical medicine and Nutritional physiology) / 環境生理学(含体力医学・栄養生理学)
Except Principal Investigator
General physiology / Biological Sciences / Anesthesiology/Resuscitation studies / Environmental physiology (including Physical medicine and Nutritional physiology) / Neurophysiology and muscle physiology / 環境生理学(含体力医学・栄養生理学)
Keywords
Principal Investigator
バゾプレッシン / オキシトシン / 遺伝性多飲マウス / 視床下部 / 視索上核 / 室傍核 / パッチクランプ法 / カルシウム画像解析 / vasopressin / supraoptic nucleus … More / バゾプレシン / PACAP / 遺伝子解析 / In situ hybridization法 / 飲水行動 / Inbred polydipsic mouse / drinking behavior / hypothalamus / サイトカイン / 自律神経 / インビボマイクロダイアリーシス / ラットアジュバンド関節炎 / 視床下部・下垂体・副腎皮質系 / 遺伝多飲マウス / 免疫異常 / ラットアジュバント関節炎 / c-fos蛋白 / mRNA / ストレス / cytokine / renal sympathetic nerve activity / microdialysis / paraventricular nucleus / inbred polydipsic mice / adjuvant arthritis / hypothalamo-pituitary-adrenal axis / 唾液腺 / 味覚神経 / 侵害受容行動 / 胸腺 / グルココルチコイド受容体 / 学習行動解析 / V2受容体遺伝子 / DNA合成能 / NK細胞活性 / 抗利尿効果 / 上喉頭神経 / 遺伝性多飲(STR / N)マウス / c-fos mRNA / グルココルチコイド / バゾプレッシン遺伝子 / 脳スライス標本 / 細胞内Ca^<2+>濃度の画像解析 / genetically polydipsic mice / salivary gland / laryngeal nerve / nociceptice response / thymus / glucocorticoid receptor / learning behavior / プロスタグランディン / ホールセルパッチクランプ / 下垂体中葉 / 膜電位依存性Ca^<2+>電流 / 非選択的陽イオン電流 / 抑制性シナプス電流 / 視床下部視索上核 / ホールセルパッチクランプ法 / Ca^<2+>画像解析法 / 抑制性シナプス後電位 / 非選択性陽イオンチャネル / EP受容体 / FP受容体 / パッチクランプ / Prostaglandins / Whole-cell patch-clamp / Ca^<2+> imaging / Pars intermedia / voltage-dependent Ca^<2+> / non-selective cation channels / Inhibitory postsynaptic currents / アドレノメュリン / オレキシン / レプチン / ウロコルチン / アドレノメデユリン / 循環 / ペプチド / イオンチャネル / 学習 / Vasopressin / Adrenomedullin / Oxytocin / Orexin / Leptin / Urocortin / 神経内分泌 / Neurosecretion / Paraventricular nucleus / Supraoptic nucleus / 脳薄切標本 / 神経ペプチド / 神経分泌ニュ-ロン / ネコ・ラット急性実験 / 神経回路網 / 覚醒ラット / 賢交感神経 / 腎交感神経 / 体液・循環調節 / 神経回路網の解析 / 自律神経活動 / 脳スライス実験 / 胃からの求心性入力 / エンドセリン / セロトニン / 水分調節 / 自律神経系 / 中枢内神経回路 / 脳スライス / 化学感受性ニューロン / Brain slice preparation / Neuropeptides / Neurosecretory neuron / Anestetized cat and rat / Neural network / Conscious rat / Renal sympathetic nerve activity … More
Except Principal Investigator
神経内分泌 / PACAP / バゾプレッシン / 視床下部 / 視索上核 / アドレノメデュリン / PAMP / adrenomedullin / 自律神経 / CCK-8 / 体温調節 / 静脈麻酔薬 / プロポフォール / サイアミラル / GABA / Ca^<2+>電流 / 脳腸ペプチド / 脳腸ホルモン / 進化 / 分泌 / 受容認識 / 情報伝達 / 病態 / 水分代謝 / 環境適応 / 飲水 / 中枢性体液調節 / 水分代謝の比較生理学 / 水分代謝と体温 / 水分代謝と循環 / 予測制御 / 飲水行動 / 水代謝の比較生理学 / Water metabolism / Environmental adaptation / Drinking / Central control of water balance / Comparative physiology / Water balance and body temperature / Water balance and circulation / feedforward control / Ca^<2+>画像解析 / パッチクランプ / 視床下部視索上核 / GABA_B受容体 / プロスタグランディンE_2 / Caffeine / Ryanodin感受性Ca^<2+>ストア / 非選択性陽イオンチャネル / Ryanodine感受性Ca^<2+>ストア / カルシウム画像解析 / プロスタグランディン / サイトカイン / Ca^<2+> imaging / Patch clamp / supraoptic nucleus / GABA_B receptors / Prostaglandin E_2 / Ryanodine Ca^<2+> stores / non-selective cation channels / 生理活性ペプチド / 循環調節 / 病態生理 / 受容体 / トランスジェニック動物 / ノックアウト動物 / 循環器疾患 / モノクローナル抗体 / 探索医療 / 降圧ペプチド / 心不全 / 動脈硬化 / アドレノメデュリン遺伝子 / 循環調節機構 / 生体内制御機構 / 生合成機構 / AM遺伝子 / AMシンポジウム / ラジオイムノアッセイ / 循環調節因子 / 血管作動性ペプチド / C末端アミド化 / biologically active peptide / circulation control / pathophysiology / receptor / transgenic animal / knockout mouse / アドレノメデユリン / 血液脳関門 / 血管内皮細胞 / 脳神経 / 脳脊髄液 / タイトジャンクション / ストレス / グリア細胞 / mRNA / RT-PCR怯 / RAMP-1,-2,-3 / オキシトシン / Fos蛋白 / 血圧 / 室傍核 / blood-brain barrier / endothelial cells / central nervous system / cerebrospinal fluid / tight junction / stress / チトクローム / 酸化還元位 / ノンスパイキングニューロン / 視視策上核 / 蝸牛有毛細胞 / 扁桃体内側核 / 松果体 / Cytochromes / Redox state / CCK-octapeptide / Non-spiking neurone / Substance P / Oxytocin / Triphosphoinositide (TPI) / 化学感受性ニュ-ロン / 認知関連ニュ-ロン / 神経移植 / 嗅細胞 / 視床下部温度感受性ニュ-ロン / 酸性線維芽細胞成長因子 / 視床下部神経分泌ヒスタミン / 海馬学習関連ニュ-ロン / 視床下部温度ニュ-ロン / 肝門脈IL-1βセンサ- / 化学感受性ニューロン / 海馬方向選択ニューロン / 脳Na利尿ホルモン / セロトニンEC細胞 / 脳移植 / 免疫サイトカイン / 不斉合成 / 情報行動 / 神経的制御 / 化学的制御 / ペプチド / 有機酸 / 本能行動 / 脳内移殖 / chemosensitive neuron / direction-related neuron / neural transplantation / olfactory receptor neuron / hypothalamic thermosensitive neuron / autonomic nerve / acidic fibroblast growth factor / hypothalamic neuronal histamine / 滲透圧調節 / 摂食代謝調節 / 内在性生理活性物質 / FGF / インターフェロン / IL-1 / アンギオテンシン / ANP / コルチコステロン / グルカゴン / ニューロテンシン / VIP / TNF / ボンベシン / グルカブン / ニューロランシン / ILー1 / CCKー8 / Thermoregulation / Osmoregulation / Food Intake / Endogenous Neurosubstances / Fibroblast Growth Factor / Interferon / Interleukins Less
  • Research Projects

    (17 results)
  • Co-Researchers

    (54 People)
  •  The localization and physiological role of adrenomedullin and related-peptides in the central nervous systemPrincipal Investigator

    • Principal Investigator
      UETA Yoichi, 山下 博
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  Role of Cardiovascular-related Peptides in the Brain : Genetic, Molecular Biological, Morphological and Physiological Aspects.Principal Investigator

    • Principal Investigator
      YAMASHITA Hiroshi
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Environmental physiology (including Physical medicine and Nutritional physiology)
    • Research Institution
      University of Occupational and Environmental Health
  •  The study of physiological and pathophysiological roles of adrenomedullin and related peptides.

    • Principal Investigator
      ETO Tanenao
    • Project Period (FY)
      1998 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Miyazaki Medical College
  •  Molecular and Cellular Biology in Mechanism of Body Fluid Homeostasis (Analysis of Inter- and Intra-Cellular Signalling in the Neurosecretory Cells)Principal Investigator

    • Principal Investigator
      YAMASHITA Hiroshi
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Environmental physiology (including Physical medicine and Nutritional physiology)
    • Research Institution
      University of Occupational and Environmental Health
  •  免疫サイトカイン・神経ペプチド麻酔関連薬の視床下部神経内分泌細胞への影響

    • Principal Investigator
      井上 義崇
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  Analysis of the mechanism of immune signal transduction to hypothalamic neuroendocrine cellsPrincipal Investigator

    • Principal Investigator
      YAMASHITA Hiroshi
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Environmental physiology (including Physical medicine and Nutritional physiology)
    • Research Institution
      University of Occupational and Environmental Health
  •  バゾプレッシン・オキシトシンによる生体調節機序の解明-分子生物学・形態学・薬理学及び生理学的アプローチ-Principal Investigator

    • Principal Investigator
      山下 博
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  The role of water metabolism on the environmental adaptation

    • Principal Investigator
      MORIMOTO Taketoshi
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Environmental physiology (including Physical medicine and Nutritional physiology)
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Neuroendocrine and immune system in genetically polydipsic mice and development of animal model in response to environmental stressPrincipal Investigator

    • Principal Investigator
      YAMASHITA Hiroshi
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Environmental physiology (including Physical medicine and Nutritional physiology)
    • Research Institution
      University of Occupational and Environmental Health
  •  Analysis with Ca2+ imaging and membrane potential measurement in neuroendocrine cells

    • Principal Investigator
      SHIBUYA Izumi
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General physiology
    • Research Institution
      University of Occupational and Environmental Health
  •  Role of immunocytokine on the neuroendocrine sysytemPrincipal Investigator

    • Principal Investigator
      YAMASHITA Hiroshi
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      環境生理学(含体力医学・栄養生理学)
    • Research Institution
      University of Occupational and Environmental Health
  •  Central mechanisms of drinking behavior in inbred polydipsic mice : molecular and physiological analysisPrincipal Investigator

    • Principal Investigator
      YAMASHITA Hiroshi
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      University of Occupational and Environmental Health
  •  Roles of Neuropeptides on Central Regulation of Water Balance and Autonomic Nervous SystemPrincipal Investigator

    • Principal Investigator
      YAMASHITA Hiroshi
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      環境生理学(含体力医学・栄養生理学)
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  生体調節系における脳腸ペプチドの役割

    • Principal Investigator
      KANNO Tomio
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      General physiology
    • Research Institution
      Hokkaido University
  •  Neuronal and chemical control of emotical behavior

    • Principal Investigator
      OOMURA Yutaka
    • Project Period (FY)
      1987 – 1989
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      Neurophysiology and muscle physiology
    • Research Institution
      Kyushu University
  •  New Endogenous Substances Controlling Different Homeostatic Functions.

    • Principal Investigator
      HORI Tetsuro
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      環境生理学(含体力医学・栄養生理学)
    • Research Institution
      Saga Medical School
  •  Paracrine secretion; its function, morphology and concept

    • Principal Investigator
      KANNO Tomio
    • Project Period (FY)
      1985 – 1986
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      General physiology
    • Research Institution
      Hokkaido University
  • 1.  UETA Yoichi (10232745)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 0 results
  • 2.  SHIBUYA Izumi (50162649)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 3.  INENAGA Kiyotoshi (90131903)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 4.  KANNAN Hiroshi (00049058)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 5.  KAWATA Mitsuhiro (60112512)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 6.  HORI Tetsuro (00022814)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 7.  KANNO Tomio (50009982)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  OTSUKA Masanori (60013801)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  HISADA Mituhiko (70000768)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  YANAIHARA Noboru (80046250)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  KABASHIMA Narutoshi (80279322)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  KANGAWA Kenji (00112417)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  OOMURA Yutaka (30019517)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  DREIFUSS J.J
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 15.  KOIZUMI Kiyo
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 16.  NAGATOMO Toshihisa (50258604)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  MORIMOTO Taketoshi (30079694)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  TAKEI Yoshio (10129249)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  SHIRAKI Keizo (00035453)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  YAMASHITA Uki (00028680)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  ETO Tanenao (10038854)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  MINAMINO Naoto (50124839)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  NAKAO Kazuwa (00172263)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  FUJITA Toshiro (10114125)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  KITAMURA Kazuo (50204912)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  NOGUCHI Jun (00330978)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  SERINO Ryota (00309957)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  YANAGISAWA Keiji (20064363)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  ONODA Norihiko (60106903)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  ONO Taketoshi (50019577)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  NIIJIMA Akira (20018287)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  NAGASAKA Tetsuo (80023646)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  NAKAYAMA Teruo (80022763)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  SANO Yutaka (00079683)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  OSAKA Toshimasa (30152101)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  井上 義崇 (60279346)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 37.  重松 昭生 (30037428)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 38.  小林 繁 (00018342)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 39.  細見 弘 (70030864)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 40.  根来 英雄 (90018903)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 41.  大磯 ユタカ (40203707)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 42.  TRIBOLLET E.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 43.  KOIZUMI K.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 44.  PFAFF D.W.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 45.  KOIZUMI K
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 46.  PFAFF D.W
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 47.  MASSAKO KADE
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 48.  KIYOMI KOIZU
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 49.  KOIZUMI Kiyomi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 50.  KADEKARO Masako
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 51.  KADEKARO Mas
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 52.  TRIBOLLET El
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 53.  KOW Lee Ming
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 54.  VALE Wylie
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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