Shigematsu Akio 重松昭生

… Alternative Names

Researcher Number	30037428
Other IDs
External Links
Affiliation (Current)	2018 : 産業医科大学, 名誉教授、学長等, 名誉教授
Affiliation (based on the past Project Information) *help	2008 : 産業医科大学, 名誉教授 2004 – 2007 : UOEH, President, 学長 2004 : 産業医科大学, 医学部, 副学長 2002 – 2004 : UOEH, The faculty of medicine, professor, 副学長 1995 – 2001 : 産業医科大学, 医学部, 教授 … More
Review Section/Research Field	Principal Investigator Anesthesiology/Resuscitation studies / Anesthesiology/Resuscitation studies / 麻酔学 Except Principal Investigator Anesthesiology/Resuscitation studies / 麻酔学 / Anesthesiology/Resuscitation studies
Keywords	Principal Investigator 麻酔薬 / ケタミン / プロポフォール / トラマドール / Anesthetics / ketamine / Sodium / イオンチャンネル / propofol / 静脈麻酔薬 … More Except Principal Investigator 麻酔薬 / プロポフォール / エンドトキシンショック / ハロセン / ケタミン / HSP-70 / 静脈麻酔薬 / エンフルラン / Isoflurane / Toll like receptor / イソフルラン / 副腎髄質 / イオン・チャンネル / アフリカツメガエル卵母細胞発現系 / Halothane / TNF / Protein Kinase C (PKC) / phagocytosis / CAP18 / Gq蛋白 / MIF / K^+ / チオペンタール / カラギ-ナン / Innate immunit / Cytokine / chlodronate / lung injury / Enflurane / Xenous ooctes発現系 / 【Ca^(2+)】 / 下行性疼痛抑制系 / 肺傷害 / Surgical stress / tachykinin receptors / タキキニンレセプター / コルチゾール / LPS / カテコールアミン / エンドトキシン感受性 / G蛋白 / vascular permeability / IL-10 / 神経内分泌 / サブスタンスーP(NK1)レセプター / G蛋白共役型受容体 / サブスタンス-P受容体 / TLR4 / G蛋白質共役型受容体 / 燐酸化酵素 / Gq蛋白結合受容体 / イソフルレン / 自然免疫 / Oxygen burst / 鎮痛薬 / 全身麻酔薬 / Peptide-IgG conjugate / TLR2 / RT-PCR(reverse transcriptase-polymerase chain reaction)法 / 痛み / endotoxin / アミントランスポーター / エンドトキシン / CAP 18 / Ennflurane / Human whole blood / ロイコトルエン / 血小板活性化因子 / カテコールアミン分泌 / Protein G / Ca^<2+> / Na^+ / 副腎髄質細胞 / Ca^<2+>依存性Cl^-チャネル / 疼痛機序 / Ca^<2+>電流 / Gi / バゾプレッシン / Protein Kinase C / Anesthesia / GABA / ジアゼパム / Bactericidal / sepsis / 抗TNF抗体 / CGRP受容体 / LPS Neutralizing / ヒト全血 / マクロファージ / 殺菌作用 / 食細胞機能 / ノルアドレナリントランスポーター / LPS中和作用 / Cl2MDP / 疼痛メカニズム / NATmRNA / タキキニンレセプター. / リポソーム / Xenopus oocytes / Gq coupled receptor / サイアミラル / 【Na^+】 / Endotoxic shock / 外科侵襲 / 細菌貪食能 / サイトカイン / Xenopus oocytes発現系 / Cannabinoid Receptor / Substance preceptor / ドロペリドール / ノルアドレナリン / 合成CAP18免疫グロブリン / 肺障害 / イオンチャネル / Protein Kinase C(PKC) / 麻酔作用機序 / C12MDP / 外科浸襲 / ムスカリン受容体 / PACAP / カナビノイド受容体 / Xenopus oocyte / 脊髄後根神経節(DRG)細胞 / 合成CAP18免疫グログリン / セボフルラン / liposome / アパミン / Protein kinase C / サブスタンス-P(NK1)レセプター Less

The study on the G protein coupled receptors to find the new analgesicsPrincipal Investigator
- Principal Investigator
  
  MINAMI Koichiro, 重松昭生
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  University of Occupational and Environmental Health, Japan
麻酔薬作用における中枢神経系各部位の果たす役割解析Principal Investigator
- Principal Investigator
  
  重松昭生
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  University of Occupational and Environmental Health, Japan
麻酔薬の動脈硬化予防作用の臨床応用を目指した研究-麻酔薬の新たなる作用の検討-Principal Investigator
- Principal Investigator
  
  重松昭生
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  University of Occupational and Environmental Health, Japan
The study of antinociceptive effects of anesthetics and analgesics using dorsal root ganglia cells.Principal Investigator
- Principal Investigator
  
  SHIGEMATSU Akio
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  University of Occupational Environmental Health(UOEH)
Innate immunity and expressions of TLRs during upper abdominal surgery
- Principal Investigator
  
  OGATA Masanori
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  University of Occupational Environmental Health(UOEH)
The effects of anesthetics and ethanol on cannabinoid receptor function.
- Principal Investigator
  
  KAMOCHI Masayuki
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  University of Occupational and Environmental Health, Japan
The mechanisms of analgesic effects of Tramadol and AlphaxalonePrincipal Investigator
- Principal Investigator
  
  SHIGEMATSU Akio
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  University of Occupational Environmental Health (UOEH)
静脈麻酔薬のノルアドレナリントランスポーターに対する作用機序の解析
- Principal Investigator
  
  相原啓二
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  University of Occupational and Environmental Health, Japan
Effects of Anesthetics on tachykinin Receptors Expressed in Xenopus Oocytes
- Principal Investigator
  
  SATA Takeyoshi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  University of Occupational and Environmental Health(UOEH)
The effects of intravenous anesthetics on aortic smooth muscle cells proliferation in vivo and in vitroPrincipal Investigator
- Principal Investigator
  
  SHIGEMATSU Akio
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Uinversity of Occupational Environmental Health (UOEH)
The effect of CAP18-immunoglobulin G conjugate on endotoxin shock.
- Principal Investigator
  
  OTGATA Masanori
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  University of Occupational Environmental Health (UOEH)
The effects of alveolar macrophage depletion by liposome technique on LPS-induced lung injury.
- Principal Investigator
  
  KAMOCHI Masayuki
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  University of Occupational Environmental Health (UOEH)
The effect of anesthetics on mesangial cells proliferation via protein kinase pathway.Principal Investigator
- Principal Investigator
  
  SHIGEMATSU Akio
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  University of Occupational Environmental Health(UOEH)
腎炎モデル動物を用いた慢性腎障害に対する麻酔薬の腎保護作用の検討Principal Investigator
- Principal Investigator
  
  重松昭生
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  University of Occupational and Environmental Health, Japan
免疫サイトカイン・神経ペプチド麻酔関連薬の視床下部神経内分泌細胞への影響
- Principal Investigator
  
  井上義崇
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  University of Occupational and Environmental Health, Japan
神経シナプス間隙でのニューロトランスミッター動態に及ぼす全身麻酔薬の作用の解析
- Principal Investigator
  
  佐多竹良
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  University of Occupational and Environmental Health, Japan
麻酔薬の腎機能保護作用の解析-ラット腎培養メサンギウム細胞を用いた検討-Principal Investigator
- Principal Investigator
  
  重松昭生
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  University of Occupational and Environmental Health, Japan
サイトカインのカラギーナン微量エンドトキシンショックに及ぼす影響Principal Investigator
- Principal Investigator
  
  重松昭生
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  University of Occupational and Environmental Health, Japan
エンドトキシンショックによる多臓器不全モデルの確立とその病態の解析
- Principal Investigator
  
  OTGATA Masanori
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  麻酔学
- Research Institution
  University of Occupational and Environmental Health, Japan
副腎髄質の電位依存性Kチャンネル並びにCa依存性Kチャンネルに対する麻酔薬の影響
- Principal Investigator
  
  緒方政則
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  麻酔学
- Research Institution
  University of Occupational and Environmental Health, Japan
Action of anesthetics on acetylcholine receptor and voltage-dependent Na channel in cultured adrenal medullary cells.Principal Investigator
- Principal Investigator
  
  SHIGEMATSU Akio, 高良裕
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  麻酔学
- Research Institution
  University of Occupational and Environmental Health, School of Medicine.
Naチャンネル,Caチャンネル並びにKチャンネルに対する麻酔薬の影響-培養副腎髄
- Principal Investigator
  
  TAKARA Hiroshi
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  麻酔学
- Research Institution
  University of Occupational and Environmental Health, Japan

All 2007

All Journal Article

[Journal Article] Dexmedetomidine inhibits muscarinic type 3 receptors expressed in Xenopus oocytes and muscarine-induced intracellular Ca^<2+> elevation in cultured rat dorsal root ganglia cells.2007
- Author(s)
  Takizuka A, Minami K, Uezono Y, Horishita T, Yokoyama T, Shiraishi M, Sakurai T, Shigematsu A, Ueta Y
- Journal Title
  
  Naunyn Schmiedebergs Arch Pharmacol. 375(5)(Epub)
  
  Pages : 293-301
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390410

1. MINAMI Koichiro (70279347)

# of Collaborated Projects : 12results

# of Collaborated Products : 1results
2. SATA Takeyoshi (60128030)

# of Collaborated Projects : 5results

# of Collaborated Products : 0results
3. UEZONO Yasuhito (20213340)

# of Collaborated Projects : 5results

# of Collaborated Products : 1results
4. OTGATA Masanori (70169176)

# of Collaborated Projects : 4results

# of Collaborated Products : 0results
5. TAKARA Hiroshi (30148952)

# of Collaborated Projects : 4results

# of Collaborated Products : 0results
6. HORISHITA Takahumi (40369070)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
7. SHIRAISHI Munehiro (40389458)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
8. WADA Akihiko (30131949)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
9. KAWASAKI Takashi (60299633)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
10. UETA Yoichi (10232745)

# of Collaborated Projects : 2results

# of Collaborated Products : 1results
11. KOHRIYAMA Kazuaki (80258623)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
12. KAMOCHI Masayuki (90204643)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
13. 青山和義 (10212391)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
14. SEO Norimasa (40093257)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
15. KOGA Kazunori (20248587)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
16. ISHIMURA Hiroshi (40289583)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
17. WATANABE Hiroyuki (90220920)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
18. SAGATA Kenichiro (30331002)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
19. NANDATE Kouichiroh (50299632)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
20. 松本尚浩 (10239105)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
21. 末永俊郎 (90269069)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
22. 井上義崇 (60279346)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
23. 山下博 (00030841)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
24. 柳原延章 (80140896)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
25. 相原啓二 (70258622)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
26. 瀬川賀世子 (70289578)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
27. 横山徹 (80425321)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
28. 瓜生佳代 (20309975)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
29. 尾方純一 (50352331)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results

Shigematsu Akio 重松 昭生

SHIGEMATSU Akio 重松 昭生

重松 昭生 シゲマツ アキオ

Research Projects

Research Products

Co-Researchers

The study on the G protein coupled receptors to find the new analgesicsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

麻酔薬作用における中枢神経系各部位の果たす役割解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

麻酔薬の動脈硬化予防作用の臨床応用を目指した研究-麻酔薬の新たなる作用の検討-Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The study of antinociceptive effects of anesthetics and analgesics using dorsal root ganglia cells.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The mechanisms of analgesic effects of Tramadol and AlphaxalonePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The effects of intravenous anesthetics on aortic smooth muscle cells proliferation in vivo and in vitroPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The effect of anesthetics on mesangial cells proliferation via protein kinase pathway.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

腎炎モデル動物を用いた慢性腎障害に対する麻酔薬の腎保護作用の検討Principal Investigator

Principal Investigator

Shigematsu Akio 重松昭生

SHIGEMATSU Akio 重松昭生

重松昭生シゲマツアキオ