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Shigematsu Akio  重松 昭生

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SHIGEMATSU Akio  重松 昭生

重松 昭生  シゲマツ アキオ

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Researcher Number 30037428
Other IDs
External Links
Affiliation (Current) 2022: 産業医科大学, 名誉教授、学長等, 名誉教授
Affiliation (based on the past Project Information) *help 2002 – 2008: UOEH, The faculty of medicine, professor, 副学長
2004: 産業医科大学, 医学部, 副学長
1995 – 2001: 産業医科大学, 医学部, 教授
1993: 産業医科大学, 医学部, 教授
1991: 産業医科大学, 医学部, 教授 … More
1988: University of Occupational and Environmental Health, School of Medicine, Department of Anesthesiology, Professor., 医学部・麻酔科, 教授
1988: 産業医科大学, 医学部・麻酔科学, 教授
1987: 産業医科大学, 麻酔科学教室, 教授
1986: 産業医科大学, 医学部・麻酔学, 教授 Less
Review Section/Research Field
Principal Investigator
Anesthesiology/Resuscitation studies / Anesthesiology/Resuscitation studies / 麻酔学
Except Principal Investigator
Anesthesiology/Resuscitation studies / 麻酔学 / Anesthesiology/Resuscitation studies
Keywords
Principal Investigator
ケタミン / 麻酔薬 / プロポフォール / トラマドール / Anesthetics / メサンギウム細胞 / 細胞増殖 / [^3H]-thymidine / イオンチャネル / 静脈麻酔薬 … More / ketamine / propofol / Xenopus oocytes / GF109203X / イオンチャンネル / Calcium / Sodium / nitric oxide / tumor necrosis factor / エンドトキシン / カラギーナン / 細胞内cAMP濃度 / 腎炎モデル / アドレノメデュリン / [^3H]-thymidineの取り込み / IL-1 / IL-6 / TNF / アドレノメヂュリン / サイトカイン / 血管平滑筋増殖 / 静脈性麻酔薬ケタミン / 細胞内cAMP / 血管障害性動脈硬化 / 動脈硬化 / 生活習慣病 / 動脈平滑筋 / 静脈性麻酔ケタミン / ^3H-thymidine / 細胞内リン酸化酵素 / 中枢神経系 / 脊髄 / 麻酔薬作用機序 / 一次痛覚神経 / 脊髄後角 / 受容体 / 麻酔機序 / 脊髄後根神経節細 / パッチクランプ法 / デクサメデトミジン / 腎メサンギウム細胞 / 燐酸化酵素 / [^3]-thymidine / 〔^3H〕-thymidine / protein kinase C / ラット腎メサンギウム細胞 / アフリカツメガエル卵母細胞 / mesangial cell / [^3H]tymidine / Protein Kinase / 5HT2A / Muscarinic reseptor / 血管平滑筋細胞 / protein kinase C(PKC) / 細胞 / フェンタネスト / キシロカイン / anesthetics / vascular smooth muscle / [3^H] thymidine / protein kinase C (PKC) / cell / ステロイド系麻酔薬 / アルファキサロン / 副腎髄質細胞 / アフリカツメガエル卵母細胞系 / ニコチン性アセチルコリン受容体イオンチャンネル / ノルエピネフリントランスポーター / ムスカリン受容体 / ニコチン性アセチルコリン受容体イオンチャネル / ノルアドレナリントランスポーター / 腎血流 / neurosteroid anestheticis / tramadol / alphaxalone / norepinephrine transporter / nicotinic acetylcholine receptor / adrenal medullary cells / muscarinic receptor / 吸入麻酔薬 / 脊髄後根神経節 / G蛋白共役型受容体 / アフリカツメガエル卵母細胞発現系 / サブスタンスP / オレキシンA / 電位依存性Naチャネル / ステロイド系静脈麻酔薬アルファキサロン / イソフルラン / エンフルラン / エーテル / ハロセン / 疼痛発生メカニズム / G蛋白結合受容体 / dorsal root ganglia cells / ion channels / G-protein coupled receptor (GPCR) / Xenopus oocyte / substance P / Tramadol / orexin A / Adrenal medulla / Catecholamine / Ion channels / Secretion / Anesthetics. / 副腎髄質 / アセチルコリン受容体 / カテコールアミン分泌 / Ion channel / Binding site / Catecholamine secretion … More
Except Principal Investigator
エンドトキシンショック / プロポフォール / 麻酔薬 / ケタミン / ハロセン / TNF / 静脈麻酔薬 / イオン・チャンネル / 副腎髄質 / アフリカツメガエル卵母細胞発現系 / イソフルラン / エンフルラン / Halothane / Isoflurane / HSP-70 / Toll like receptor / Protein Kinase C (PKC) / カラギ-ナン / ロイコトルエン / 血小板活性化因子 / 抗TNF抗体 / 神経内分泌 / バゾプレッシン / PACAP / サイアミラル / GABA / Ca^<2+>電流 / 副腎髄質細胞 / カテコールアミン / ノルアドレナリン / アミントランスポーター / 燐酸化酵素 / 下行性疼痛抑制系 / ノルアドレナリントランスポーター / RT-PCR(reverse transcriptase-polymerase chain reaction)法 / チオペンタール / ジアゼパム / NATmRNA / 疼痛メカニズム / 鎮痛薬 / 脊髄後根神経節(DRG)細胞 / Xenopus oocytes発現系 / ムスカリン受容体 / G蛋白共役型受容体 / イオンチャネル / 痛み / 麻酔作用機序 / Xenous ooctes発現系 / サブスタンス-P受容体 / CGRP受容体 / ドロペリドール / カテコールアミン分泌 / 【Na^+】 / 【Ca^(2+)】 / Na^+ / Ca^<2+> / K^+ / 全身麻酔薬 / アパミン / CAP18 / 合成CAP18免疫グロブリン / 殺菌作用 / LPS中和作用 / 食細胞機能 / サイトカイン / ヒト全血 / 合成CAP18免疫グログリン / CAP 18 / Peptide-IgG conjugate / Bactericidal / LPS Neutralizing / Endotoxic shock / Cytokine / Human whole blood / Cl2MDP / マクロファージ / リポソーム / 肺障害 / 肺傷害 / chlodronate / エンドトキシン / lung injury / endotoxin / sepsis / C12MDP / vascular permeability / liposome / サブスタンス-P(NK1)レセプター / Gq蛋白結合受容体 / タキキニンレセプター. / Protein Kinase C / サブスタンスーP(NK1)レセプター / タキキニンレセプター / 疼痛機序 / イソフルレン / セボフルラン / Substance preceptor / Gq coupled receptor / Xenopus oocytes / Ennflurane / tachykinin receptors / Protein kinase C / 外科侵襲 / TLR2 / TLR4 / 細菌貪食能 / IL-10 / コルチゾール / LPS / 自然免疫 / エンドトキシン感受性 / 外科浸襲 / Innate immunit / Surgical stress / phagocytosis / Oxygen burst / Anesthesia / MIF / カナビノイド受容体 / G蛋白 / Protein Kinase C(PKC) / G蛋白質共役型受容体 / Ca^<2+>依存性Cl^-チャネル / Gi / Gq蛋白 / Cannabinoid Receptor / Protein G / Xenopus oocyte / Enflurane Less
  • Research Projects

    (22 results)
  • Research Products

    (1 results)
  • Co-Researchers

    (29 People)
  •  The study on the G protein coupled receptors to find the new analgesicsPrincipal Investigator

    • Principal Investigator
      MINAMI Koichiro, 重松 昭生
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  麻酔薬作用における中枢神経系各部位の果たす役割解析Principal Investigator

    • Principal Investigator
      重松 昭生
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  麻酔薬の動脈硬化予防作用の臨床応用を目指した研究-麻酔薬の新たなる作用の検討-Principal Investigator

    • Principal Investigator
      重松 昭生
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  The study of antinociceptive effects of anesthetics and analgesics using dorsal root ganglia cells.Principal Investigator

    • Principal Investigator
      SHIGEMATSU Akio
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      University of Occupational Environmental Health(UOEH)
  •  Innate immunity and expressions of TLRs during upper abdominal surgery

    • Principal Investigator
      OGATA Masanori
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      University of Occupational Environmental Health(UOEH)
  •  The effects of anesthetics and ethanol on cannabinoid receptor function.

    • Principal Investigator
      KAMOCHI Masayuki
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  The mechanisms of analgesic effects of Tramadol and AlphaxalonePrincipal Investigator

    • Principal Investigator
      SHIGEMATSU Akio
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      University of Occupational Environmental Health (UOEH)
  •  静脈麻酔薬のノルアドレナリントランスポーターに対する作用機序の解析

    • Principal Investigator
      相原 啓二
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  Effects of Anesthetics on tachykinin Receptors Expressed in Xenopus Oocytes

    • Principal Investigator
      SATA Takeyoshi
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      University of Occupational and Environmental Health(UOEH)
  •  The effects of intravenous anesthetics on aortic smooth muscle cells proliferation in vivo and in vitroPrincipal Investigator

    • Principal Investigator
      SHIGEMATSU Akio
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Uinversity of Occupational Environmental Health (UOEH)
  •  The effect of CAP18-immunoglobulin G conjugate on endotoxin shock.

    • Principal Investigator
      OTGATA Masanori
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      University of Occupational Environmental Health (UOEH)
  •  The effects of alveolar macrophage depletion by liposome technique on LPS-induced lung injury.

    • Principal Investigator
      KAMOCHI Masayuki
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      University of Occupational Environmental Health (UOEH)
  •  The effect of anesthetics on mesangial cells proliferation via protein kinase pathway.Principal Investigator

    • Principal Investigator
      SHIGEMATSU Akio
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      University of Occupational Environmental Health(UOEH)
  •  腎炎モデル動物を用いた慢性腎障害に対する麻酔薬の腎保護作用の検討Principal Investigator

    • Principal Investigator
      重松 昭生
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  免疫サイトカイン・神経ペプチド麻酔関連薬の視床下部神経内分泌細胞への影響

    • Principal Investigator
      井上 義崇
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  神経シナプス間隙でのニューロトランスミッター動態に及ぼす全身麻酔薬の作用の解析

    • Principal Investigator
      佐多 竹良
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  麻酔薬の腎機能保護作用の解析-ラット腎培養メサンギウム細胞を用いた検討-Principal Investigator

    • Principal Investigator
      重松 昭生
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  サイトカインのカラギーナン微量エンドトキシンショックに及ぼす影響Principal Investigator

    • Principal Investigator
      重松 昭生
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  エンドトキシンショックによる多臓器不全モデルの確立とその病態の解析

    • Principal Investigator
      OTGATA Masanori
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      麻酔学
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  副腎髄質の電位依存性Kチャンネル並びにCa依存性Kチャンネルに対する麻酔薬の影響

    • Principal Investigator
      緒方 政則
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      麻酔学
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  Action of anesthetics on acetylcholine receptor and voltage-dependent Na channel in cultured adrenal medullary cells.Principal Investigator

    • Principal Investigator
      SHIGEMATSU Akio, 高良 裕
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      麻酔学
    • Research Institution
      University of Occupational and Environmental Health, School of Medicine.
  •  Naチャンネル,Caチャンネル並びにKチャンネルに対する麻酔薬の影響-培養副腎髄

    • Principal Investigator
      TAKARA Hiroshi
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      麻酔学
    • Research Institution
      University of Occupational and Environmental Health, Japan

All 2007

All Journal Article

  • [Journal Article] Dexmedetomidine inhibits muscarinic type 3 receptors expressed in Xenopus oocytes and muscarine-induced intracellular Ca^<2+> elevation in cultured rat dorsal root ganglia cells.2007

    • Author(s)
      Takizuka A, Minami K, Uezono Y, Horishita T, Yokoyama T, Shiraishi M, Sakurai T, Shigematsu A, Ueta Y
    • Journal Title

      Naunyn Schmiedebergs Arch Pharmacol. 375(5)(Epub)

      Pages: 293-301

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390410
  • 1.  MINAMI Koichiro (70279347)
    # of Collaborated Projects: 12 results
    # of Collaborated Products: 1 results
  • 2.  SATA Takeyoshi (60128030)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 3.  UEZONO Yasuhito (20213340)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 1 results
  • 4.  OTGATA Masanori (70169176)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 5.  TAKARA Hiroshi (30148952)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 6.  HORISHITA Takahumi (40369070)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 7.  SHIRAISHI Munehiro (40389458)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 8.  WADA Akihiko (30131949)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 9.  KAWASAKI Takashi (60299633)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  UETA Yoichi (10232745)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 11.  KOHRIYAMA Kazuaki (80258623)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  KAMOCHI Masayuki (90204643)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  青山 和義 (10212391)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  SEO Norimasa (40093257)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  KOGA Kazunori (20248587)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  ISHIMURA Hiroshi (40289583)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  WATANABE Hiroyuki (90220920)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  SAGATA Kenichiro (30331002)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  NANDATE Kouichiroh (50299632)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  松本 尚浩 (10239105)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  末永 俊郎 (90269069)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  井上 義崇 (60279346)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  山下 博 (00030841)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  柳原 延章 (80140896)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  相原 啓二 (70258622)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  瀬川 賀世子 (70289578)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  横山 徹 (80425321)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  瓜生 佳代 (20309975)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  尾方 純一 (50352331)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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