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Shigematsu Akio
重松 昭生
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Alternative Names
SHIGEMATSU Akio 重松 昭生
重松 昭生 シゲマツ アキオ
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Researcher Number
30037428
Other IDs
External Links
Affiliation (Current)
2022: 産業医科大学, 名誉教授、学長等, 名誉教授
Affiliation (based on the past Project Information)
*help
2002 – 2008: UOEH, The faculty of medicine, professor, 副学長
2004: 産業医科大学, 医学部, 副学長
1995 – 2001: 産業医科大学, 医学部, 教授
1993: 産業医科大学, 医学部, 教授
1991: 産業医科大学, 医学部, 教授
…
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1988: University of Occupational and Environmental Health, School of Medicine, Department of Anesthesiology, Professor., 医学部・麻酔科, 教授
1988: 産業医科大学, 医学部・麻酔科学, 教授
1987: 産業医科大学, 麻酔科学教室, 教授
1986: 産業医科大学, 医学部・麻酔学, 教授
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Review Section/Research Field
Principal Investigator
Anesthesiology/Resuscitation studies
/
Anesthesiology/Resuscitation studies
/
麻酔学
Except Principal Investigator
Anesthesiology/Resuscitation studies
/
麻酔学
/
Anesthesiology/Resuscitation studies
Keywords
Principal Investigator
ケタミン / 麻酔薬 / プロポフォール / トラマドール / Anesthetics / メサンギウム細胞 / 細胞増殖 / [^3H]-thymidine / イオンチャネル / 静脈麻酔薬
…
More
/ ketamine / propofol / Xenopus oocytes / GF109203X / イオンチャンネル / Calcium / Sodium / nitric oxide / tumor necrosis factor / エンドトキシン / カラギーナン / 細胞内cAMP濃度 / 腎炎モデル / アドレノメデュリン / [^3H]-thymidineの取り込み / IL-1 / IL-6 / TNF / アドレノメヂュリン / サイトカイン / 血管平滑筋増殖 / 静脈性麻酔薬ケタミン / 細胞内cAMP / 血管障害性動脈硬化 / 動脈硬化 / 生活習慣病 / 動脈平滑筋 / 静脈性麻酔ケタミン / ^3H-thymidine / 細胞内リン酸化酵素 / 中枢神経系 / 脊髄 / 麻酔薬作用機序 / 一次痛覚神経 / 脊髄後角 / 受容体 / 麻酔機序 / 脊髄後根神経節細 / パッチクランプ法 / デクサメデトミジン / 腎メサンギウム細胞 / 燐酸化酵素 / [^3]-thymidine / 〔^3H〕-thymidine / protein kinase C / ラット腎メサンギウム細胞 / アフリカツメガエル卵母細胞 / mesangial cell / [^3H]tymidine / Protein Kinase / 5HT2A / Muscarinic reseptor / 血管平滑筋細胞 / protein kinase C(PKC) / 細胞 / フェンタネスト / キシロカイン / anesthetics / vascular smooth muscle / [3^H] thymidine / protein kinase C (PKC) / cell / ステロイド系麻酔薬 / アルファキサロン / 副腎髄質細胞 / アフリカツメガエル卵母細胞系 / ニコチン性アセチルコリン受容体イオンチャンネル / ノルエピネフリントランスポーター / ムスカリン受容体 / ニコチン性アセチルコリン受容体イオンチャネル / ノルアドレナリントランスポーター / 腎血流 / neurosteroid anestheticis / tramadol / alphaxalone / norepinephrine transporter / nicotinic acetylcholine receptor / adrenal medullary cells / muscarinic receptor / 吸入麻酔薬 / 脊髄後根神経節 / G蛋白共役型受容体 / アフリカツメガエル卵母細胞発現系 / サブスタンスP / オレキシンA / 電位依存性Naチャネル / ステロイド系静脈麻酔薬アルファキサロン / イソフルラン / エンフルラン / エーテル / ハロセン / 疼痛発生メカニズム / G蛋白結合受容体 / dorsal root ganglia cells / ion channels / G-protein coupled receptor (GPCR) / Xenopus oocyte / substance P / Tramadol / orexin A / Adrenal medulla / Catecholamine / Ion channels / Secretion / Anesthetics. / 副腎髄質 / アセチルコリン受容体 / カテコールアミン分泌 / Ion channel / Binding site / Catecholamine secretion
…
More
Except Principal Investigator
エンドトキシンショック / プロポフォール / 麻酔薬 / ケタミン / ハロセン / TNF / 静脈麻酔薬 / イオン・チャンネル / 副腎髄質 / アフリカツメガエル卵母細胞発現系 / イソフルラン / エンフルラン / Halothane / Isoflurane / HSP-70 / Toll like receptor / Protein Kinase C (PKC) / カラギ-ナン / ロイコトルエン / 血小板活性化因子 / 抗TNF抗体 / 神経内分泌 / バゾプレッシン / PACAP / サイアミラル / GABA / Ca^<2+>電流 / 副腎髄質細胞 / カテコールアミン / ノルアドレナリン / アミントランスポーター / 燐酸化酵素 / 下行性疼痛抑制系 / ノルアドレナリントランスポーター / RT-PCR(reverse transcriptase-polymerase chain reaction)法 / チオペンタール / ジアゼパム / NATmRNA / 疼痛メカニズム / 鎮痛薬 / 脊髄後根神経節(DRG)細胞 / Xenopus oocytes発現系 / ムスカリン受容体 / G蛋白共役型受容体 / イオンチャネル / 痛み / 麻酔作用機序 / Xenous ooctes発現系 / サブスタンス-P受容体 / CGRP受容体 / ドロペリドール / カテコールアミン分泌 / 【Na^+】 / 【Ca^(2+)】 / Na^+ / Ca^<2+> / K^+ / 全身麻酔薬 / アパミン / CAP18 / 合成CAP18免疫グロブリン / 殺菌作用 / LPS中和作用 / 食細胞機能 / サイトカイン / ヒト全血 / 合成CAP18免疫グログリン / CAP 18 / Peptide-IgG conjugate / Bactericidal / LPS Neutralizing / Endotoxic shock / Cytokine / Human whole blood / Cl2MDP / マクロファージ / リポソーム / 肺障害 / 肺傷害 / chlodronate / エンドトキシン / lung injury / endotoxin / sepsis / C12MDP / vascular permeability / liposome / サブスタンス-P(NK1)レセプター / Gq蛋白結合受容体 / タキキニンレセプター. / Protein Kinase C / サブスタンスーP(NK1)レセプター / タキキニンレセプター / 疼痛機序 / イソフルレン / セボフルラン / Substance preceptor / Gq coupled receptor / Xenopus oocytes / Ennflurane / tachykinin receptors / Protein kinase C / 外科侵襲 / TLR2 / TLR4 / 細菌貪食能 / IL-10 / コルチゾール / LPS / 自然免疫 / エンドトキシン感受性 / 外科浸襲 / Innate immunit / Surgical stress / phagocytosis / Oxygen burst / Anesthesia / MIF / カナビノイド受容体 / G蛋白 / Protein Kinase C(PKC) / G蛋白質共役型受容体 / Ca^<2+>依存性Cl^-チャネル / Gi / Gq蛋白 / Cannabinoid Receptor / Protein G / Xenopus oocyte / Enflurane
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Research Projects
(
22
results)
Research Products
(
1
results)
Co-Researchers
(
29
People)
Project Start Year (Newest)
Project Start Year (Oldest)
The study on the G protein coupled receptors to find the new analgesics
Principal Investigator
Principal Investigator
MINAMI Koichiro
, 重松 昭生
Project Period (FY)
2007 – 2008
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Anesthesiology/Resuscitation studies
Research Institution
University of Occupational and Environmental Health, Japan
麻酔薬作用における中枢神経系各部位の果たす役割解析
Principal Investigator
Principal Investigator
重松 昭生
Project Period (FY)
2006 – 2007
Research Category
Grant-in-Aid for Exploratory Research
Research Field
Anesthesiology/Resuscitation studies
Research Institution
University of Occupational and Environmental Health, Japan
麻酔薬の動脈硬化予防作用の臨床応用を目指した研究-麻酔薬の新たなる作用の検討-
Principal Investigator
Principal Investigator
重松 昭生
Project Period (FY)
2004 – 2005
Research Category
Grant-in-Aid for Exploratory Research
Research Field
Anesthesiology/Resuscitation studies
Research Institution
University of Occupational and Environmental Health, Japan
The study of antinociceptive effects of anesthetics and analgesics using dorsal root ganglia cells.
Principal Investigator
Principal Investigator
SHIGEMATSU Akio
Project Period (FY)
2003 – 2005
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Anesthesiology/Resuscitation studies
Research Institution
University of Occupational Environmental Health(UOEH)
Innate immunity and expressions of TLRs during upper abdominal surgery
Principal Investigator
OGATA Masanori
Project Period (FY)
2002 – 2004
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Anesthesiology/Resuscitation studies
Research Institution
University of Occupational Environmental Health(UOEH)
The effects of anesthetics and ethanol on cannabinoid receptor function.
Principal Investigator
KAMOCHI Masayuki
Project Period (FY)
2002 – 2004
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Anesthesiology/Resuscitation studies
Research Institution
University of Occupational and Environmental Health, Japan
The mechanisms of analgesic effects of Tramadol and Alphaxalone
Principal Investigator
Principal Investigator
SHIGEMATSU Akio
Project Period (FY)
2001 – 2002
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Anesthesiology/Resuscitation studies
Research Institution
University of Occupational Environmental Health (UOEH)
静脈麻酔薬のノルアドレナリントランスポーターに対する作用機序の解析
Principal Investigator
相原 啓二
Project Period (FY)
2000 – 2001
Research Category
Grant-in-Aid for Exploratory Research
Research Field
Anesthesiology/Resuscitation studies
Research Institution
University of Occupational and Environmental Health, Japan
Effects of Anesthetics on tachykinin Receptors Expressed in Xenopus Oocytes
Principal Investigator
SATA Takeyoshi
Project Period (FY)
2000 – 2001
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Anesthesiology/Resuscitation studies
Research Institution
University of Occupational and Environmental Health(UOEH)
The effects of intravenous anesthetics on aortic smooth muscle cells proliferation in vivo and in vitro
Principal Investigator
Principal Investigator
SHIGEMATSU Akio
Project Period (FY)
1999 – 2000
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Anesthesiology/Resuscitation studies
Research Institution
Uinversity of Occupational Environmental Health (UOEH)
The effect of CAP18-immunoglobulin G conjugate on endotoxin shock.
Principal Investigator
OTGATA Masanori
Project Period (FY)
1998 – 1999
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Anesthesiology/Resuscitation studies
Research Institution
University of Occupational Environmental Health (UOEH)
The effects of alveolar macrophage depletion by liposome technique on LPS-induced lung injury.
Principal Investigator
KAMOCHI Masayuki
Project Period (FY)
1998 – 1999
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Anesthesiology/Resuscitation studies
Research Institution
University of Occupational Environmental Health (UOEH)
The effect of anesthetics on mesangial cells proliferation via protein kinase pathway.
Principal Investigator
Principal Investigator
SHIGEMATSU Akio
Project Period (FY)
1997 – 1998
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Anesthesiology/Resuscitation studies
Research Institution
University of Occupational Environmental Health(UOEH)
腎炎モデル動物を用いた慢性腎障害に対する麻酔薬の腎保護作用の検討
Principal Investigator
Principal Investigator
重松 昭生
Project Period (FY)
1996
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Anesthesiology/Resuscitation studies
Research Institution
University of Occupational and Environmental Health, Japan
免疫サイトカイン・神経ペプチド麻酔関連薬の視床下部神経内分泌細胞への影響
Principal Investigator
井上 義崇
Project Period (FY)
1996
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Anesthesiology/Resuscitation studies
Research Institution
University of Occupational and Environmental Health, Japan
神経シナプス間隙でのニューロトランスミッター動態に及ぼす全身麻酔薬の作用の解析
Principal Investigator
佐多 竹良
Project Period (FY)
1996
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Anesthesiology/Resuscitation studies
Research Institution
University of Occupational and Environmental Health, Japan
麻酔薬の腎機能保護作用の解析-ラット腎培養メサンギウム細胞を用いた検討-
Principal Investigator
Principal Investigator
重松 昭生
Project Period (FY)
1995
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Anesthesiology/Resuscitation studies
Research Institution
University of Occupational and Environmental Health, Japan
サイトカインのカラギーナン微量エンドトキシンショックに及ぼす影響
Principal Investigator
Principal Investigator
重松 昭生
Project Period (FY)
1993
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Anesthesiology/Resuscitation studies
Research Institution
University of Occupational and Environmental Health, Japan
エンドトキシンショックによる多臓器不全モデルの確立とその病態の解析
Principal Investigator
OTGATA Masanori
Project Period (FY)
1991
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
麻酔学
Research Institution
University of Occupational and Environmental Health, Japan
副腎髄質の電位依存性Kチャンネル並びにCa依存性Kチャンネルに対する麻酔薬の影響
Principal Investigator
緒方 政則
Project Period (FY)
1988
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
麻酔学
Research Institution
University of Occupational and Environmental Health, Japan
Action of anesthetics on acetylcholine receptor and voltage-dependent Na channel in cultured adrenal medullary cells.
Principal Investigator
Principal Investigator
SHIGEMATSU Akio,
高良 裕
Project Period (FY)
1987 – 1988
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
麻酔学
Research Institution
University of Occupational and Environmental Health, School of Medicine.
Naチャンネル,Caチャンネル並びにKチャンネルに対する麻酔薬の影響-培養副腎髄
Principal Investigator
TAKARA Hiroshi
Project Period (FY)
1986
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
麻酔学
Research Institution
University of Occupational and Environmental Health, Japan
All
2007
All
Journal Article
[Journal Article] Dexmedetomidine inhibits muscarinic type 3 receptors expressed in Xenopus oocytes and muscarine-induced intracellular Ca^<2+> elevation in cultured rat dorsal root ganglia cells.
2007
Author(s)
Takizuka A, Minami K, Uezono Y, Horishita T, Yokoyama T, Shiraishi M, Sakurai T, Shigematsu A, Ueta Y
Journal Title
Naunyn Schmiedebergs Arch Pharmacol. 375(5)(Epub)
Pages
: 293-301
Peer Reviewed
Data Source
KAKENHI-PROJECT-19390410
# of Projects (Dsc)
# of Projects (Asc)
1.
MINAMI Koichiro
(70279347)
# of Collaborated Projects:
12 results
# of Collaborated Products:
1 results
2.
SATA Takeyoshi
(60128030)
# of Collaborated Projects:
5 results
# of Collaborated Products:
0 results
3.
UEZONO Yasuhito
(20213340)
# of Collaborated Projects:
5 results
# of Collaborated Products:
1 results
4.
OTGATA Masanori
(70169176)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
5.
TAKARA Hiroshi
(30148952)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
6.
HORISHITA Takahumi
(40369070)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
7.
SHIRAISHI Munehiro
(40389458)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
8.
WADA Akihiko
(30131949)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
9.
KAWASAKI Takashi
(60299633)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
10.
UETA Yoichi
(10232745)
# of Collaborated Projects:
2 results
# of Collaborated Products:
1 results
11.
KOHRIYAMA Kazuaki
(80258623)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
12.
KAMOCHI Masayuki
(90204643)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
13.
青山 和義
(10212391)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
14.
SEO Norimasa
(40093257)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
15.
KOGA Kazunori
(20248587)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
16.
ISHIMURA Hiroshi
(40289583)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
17.
WATANABE Hiroyuki
(90220920)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
18.
SAGATA Kenichiro
(30331002)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
19.
NANDATE Kouichiroh
(50299632)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
20.
松本 尚浩
(10239105)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
21.
末永 俊郎
(90269069)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
22.
井上 義崇
(60279346)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
23.
山下 博
(00030841)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
24.
柳原 延章
(80140896)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
25.
相原 啓二
(70258622)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
26.
瀬川 賀世子
(70289578)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
27.
横山 徹
(80425321)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
28.
瓜生 佳代
(20309975)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
29.
尾方 純一
(50352331)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
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