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WATABE Tadashi
渡部 烈
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Researcher Number
00057316
Affiliation (based on the past Project Information)
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1986 – 1993: 東京薬科大学, 薬学部, 教授
1992: Tokyo College of Pharmacy, Professor, 教授
1990: 東京薬大, 薬学部, 教授
1986: 東京薬大, 薬学部, 教授
Review Section/Research Field
Principal Investigator
Biological pharmacy
Except Principal Investigator
Pathological medical chemistry
Keywords
Principal Investigator
脂質過酸化 / 脂肪酸ヒドロペルオキシド / 脂質過酸化物 / 酸素フリーラジカル / 生体膜 / グルタチオンS-トランスフェラーゼ / リン脂質ヒドロペルオキシド / コレステロールヒドロペルオキシド / 加齢マーカー物質 / 老化
…
More
/ ラット肝 / ミクロソーム / 過酸化脂質 / 生体膜防御機構 / グルタチオンペルオキシダーゼ活性 / cDNAクローニング / 肝ミクロソ-ム / 酸素フリ-ラジカル / グルタチオン / グルタチオンペルオキシダ-ゼ / 肝細胞質 / グルタチオントランスフェラ-ゼ / Oxygen Free Radical / Lipid Peroxidation / Biomembrane / Glutathione S-Transferase / Phospholipid Hydroperoxide / Cholesterol Hydroperoxide / Marker Substanec in Aging / Aging / 活性酵素 / ミクロゾーム脂質過酸化 / エポキシド / グルタチオンペルオキシダーゼ / ロイコトリエンA_4 / エポキシドヒドロラーゼ / 肝ミクロゾーム脂質過酸化 / 活性酸素 / 肝小胞体膜リン脂質 / パーオキシラジカル / 変異原性エポキシド / 抗酸化剤 / 肝ミクロゾームの脂質過酸化 / 脂質パーオキシラジカル / 膜脂質アラキドン酸 / ジヒドロベンゾ〔a〕ピレン / アフラトキシン【B_1】 / Active oxygen / Microsomal lipid peroxidation / Fatty acid hydroperoxide / Epoxide / Glutathione peroxidase / Leukotriene A_4
…
More
Except Principal Investigator
代謝的活性化 / DNA傷害 / 肝発がん / 前がん病変 / 酵素変異 / 遺伝子クローニング / 遺伝子発現制御機構 / 環境変異原 / 代謝活性化 / 複合作用 / ヘテロサイクリックアミン / 種差 / 性差 / 化学発癌 / アレーン / クロロフィル / 活性中間体 / DNA修復 / DNA付加体 / チトクロムP-450 / ニトロピレン / がん遺伝子 / 解毒 / 抱合反応 / グルタチオン / グルタチオンSートランスフェラーゼ / タンパク質工学 / 腸肝循環 / 抱合体 / 癌原物質 / 臓器特異性 / ヒドロキシアリ-ルアミン / チトクロームP-450 / 細胞増殖 / P450 / アセチル化酵素 / サルフォトランスフェラ-ゼ / O-アセチラ-ゼ / グルタチオン Sートランスフェラーゼ / チトクロムPー450 / サルフォトランスフェラーゼ / Oーアセチラーゼ / ニトロアレーン / メンチルアレーン / wst突然変異マウス / S-トランスフェラーゼ / ヒトへの外挿 / N-水酸化体 / 亜硝酸 / グルタチオンS-トランスフェラーゼ / システインプロテアーゼインヒビター / 過酸化脂質 / 生体防御 / 細胞傷害 / 酸化環元 / 輸送機構 / グルタチオン Sートランスフェラ-ゼ / 酸化還元 / グルタチオンSートランスフェラ-ゼ / システィンプロテア-ゼ / Glutathione / Glutathione S-transferase / Cysteine protease inhibitor / Lipid hydroperoxide / Cell survival / Oxidative stress / Oxido-reduction / Transport system
Less
Research Projects
(
15
results)
Co-Researchers
(
27
People)
Project Start Year (Newest)
Project Start Year (Oldest)
化学発癌における活性中間体の動態と標的臓器DNA傷害-臓器および種特異性との関連
Principal Investigator
加藤 隆一
Project Period (FY)
1993
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Keio University
化学発癌における活性中間体の動態と標的臓番DNA傷害ー臓器よおび種特異性との関連
Principal Investigator
加藤 隆一
Project Period (FY)
1992
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Keio University
化学発癌における活性中間体の動態と標的臓器DNA傷害ー臓器および種特異性との関連
Principal Investigator
加藤 隆一
Project Period (FY)
1991
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Keio University
Molecular Mechanism of Defense against Stress and Metabolic Regulation by Glutathione and Its Metabolites
Principal Investigator
KUMAGAI Hidehiko
,
佐藤 清美
Project Period (FY)
1990 – 1992
Research Category
Grant-in-Aid for Co-operative Research (A)
Research Field
Pathological medical chemistry
Research Institution
KYOTO UNIVERSITY
Hirosaki University
A Novel Mechanism for Protecting of Biomembrane from Oxidative Disorder by Oxygen Free Radicals
Principal Investigator
Principal Investigator
WATABE Tadashi
Project Period (FY)
1990 – 1992
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Biological pharmacy
Research Institution
Tokyo College of Pharmacy
肝化学発癌過程の前癌細胞における遺伝子および遺伝子発現の異常の解析
Principal Investigator
佐藤 清美
Project Period (FY)
1989
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Hirosaki University
肝化学発癌過程の前癌細胞における遺伝子および遺伝子発現の異常の解析
Principal Investigator
佐藤 清美
Project Period (FY)
1988
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Hirosaki University
環境変異原の生体円代謝と複合作用
Principal Investigator
大西 克成
Project Period (FY)
1987 – 1989
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
The University of Tokushima
肝化学発癌過程の前癌細胞における遺伝子および遺伝子発現の異常の解析
Principal Investigator
佐藤 清美
Project Period (FY)
1987
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Hokkaido University
環境変異原の生体代謝と複合作用
Principal Investigator
大西 克成
Project Period (FY)
1987 – 1989
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
The University of Tokushima
癌原物質の代謝的活性化機構と発癌の特異性に関する研究ーー特にヒトの外挿
Principal Investigator
加藤 隆一
Project Period (FY)
1987 – 1988
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Keio University
環境変異原の生体内代謝と複合作用
Principal Investigator
大西 克成
Project Period (FY)
1987 – 1989
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
The University of Tokushima
癌原物質の代謝的活性化機構と発癌の特異性に関する研究ー特にヒトへの外挿
Principal Investigator
加藤 隆一
Project Period (FY)
1986 – 1987
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Keio University
Oxidation of xenobiotics by active peroxyradicals derived from lipids of hepatic endoplasmic reticulum
Principal Investigator
Principal Investigator
WATABE Tadashi Professor
Project Period (FY)
1986 – 1988
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Biological pharmacy
Research Institution
Tokyo College of Pharmacy
癌原物質の代謝的活性化機構と発癌の特異性に関する研究-特にヒトへの外挿-
Principal Investigator
加藤 隆一
Project Period (FY)
1985 – 1986
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Keio University
# of Projects (Dsc)
# of Projects (Asc)
1.
大西 克成
(10037400)
# of Collaborated Projects:
7 results
# of Collaborated Products:
0 results
2.
加藤 隆一
(40112685)
# of Collaborated Projects:
6 results
# of Collaborated Products:
0 results
3.
出川 雅邦
(50134002)
# of Collaborated Projects:
5 results
# of Collaborated Products:
0 results
4.
佐藤 清美
(50006079)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
5.
MURAMATSU Masami
(10035454)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
6.
野口 民夫
(70135721)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
7.
津田 洋幸
(10163809)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
8.
山添 康
(00112699)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
9.
長尾 美奈子
(40100151)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
10.
早津 彦哉
(10012593)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
11.
辰巳 淳
(90037581)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
12.
石川 隆俊
(30085633)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
13.
多田 万里子
(90073113)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
14.
若林 敬二
(60158582)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
15.
渡辺 民朗
(40006101)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
16.
大垣 比呂子
(00150201)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
17.
OKUDA Haruhiro
(30160807)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
18.
HIRATSUKA Akira
(20165179)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
19.
林 健志
(00019671)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
20.
立木 蔚
(90006065)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
21.
菊地 九二三
(20006117)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
22.
江角 浩安
(70160364)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
23.
KUMAGAI Hidehiko
(70027192)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
24.
HIGASHI Taneaki
(50028304)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
25.
TANIGUCHI Naoyuki
(90002188)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
26.
KATUNUMA Nobuhiko
(50035375)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
27.
OGURA Kenichiro
(10185564)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
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