NAGASAWA Kohei 長澤浩平

Researcher Number	00108721
Affiliation (based on the past Project Information) *help	2012 : 佐賀大学, 佐賀大学, 教授 2010 : 佐賀大学, 医学部, 教授 2003 – 2008 : 佐賀大学, 医学部, 教授 1997 – 2002 : 佐賀医科大学, 医学部, 教授 1995 : Saga Medical School, Internal Medicine, Professor, 医学部, 教授 … More
Review Section/Research Field	Principal Investigator 内科学一般 / 膠原病・アレルギー・感染症内科学 / Legal medicine Except Principal Investigator 膠原病・アレルギー・感染症内科学 / 内科学一般 / Kidney internal medicine / Immunology
Keywords	Principal Investigator RP105 / SLE / B細胞 / HTLV-1 / 自己抗体 / シェーグレン症候群 / B cell / アポトーシス / BCMA / 自己免疫疾患 … More Except Principal Investigator SLE / costimulatory molecule / RP105 / nephritis / LBP / B細胞 / LPS / Toll-like receptor / autoimmunity / lupus / lupus anticoagulant / RP105(CD180) / CD14 / autoantibody / inducible costimulator / 自己免疫疾患 / 自己抗体 / MD-2 / Siogren's syndrome / Systemic lupus erythematosus / 抗ATLA抗体 / Toll like receptor / ループス腎炎 / RP105(CD80) / 膠原病学 / spontaneous abortion in SLE / 川崎病 / 腎臓学 / アンケート / B cells / キメラ蛋白 / サイトカイン / SLEと自然流産 / 全身性エリテマトーデス / siRNA / 免疫グロブリン欠損症 / シェーグレン症候群 / リコンビナント蛋白 / dermatomyositis / ligand / IgM欠損 / 融合蛋白 / Immunological Regulation / ノックアウト / BAFF / 帯状疱疹 / アイソフォーム / トランスフェクタント / TLR / リガンド / 生物製剤 / cytokine / TLR4 / atuoimmune dieseases / 大腸菌発現 / bacterial expression / リコンピナント蛋白 / CHO / 全身性エリテマトーデス(SLE) / selective IgM deficiency / Toll-like レセプター / MD-1 / インターフェロン調節因子 / 発熱 / 皮膚筋炎 / Toll-likeレセプター / 変異蛋白 / SLEと感染症 / anti-HTLV-I antibodies in SLE patients / インターフェロン制御因子 / 免疫学的治療 / recombinant protein / データベース / 成人発症スティル病 / 関節炎 Less

Role of the interferon regulatory factor 5 in the development of lupus nephritis
- Principal Investigator
  
  TADA Yoshifumi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Saga University
The development of new therapeutic approaches to autoantibody-producing RP105-negative B cells in autoimmune diseases
- Principal Investigator
  
  KOARADA Syuichi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Saga University
Total analysis of RP105 molecule on B cells : Its function and application to treatment in autoimmune diseasesPrincipal Investigator
- Principal Investigator
  
  NAGASAWA Kohei
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Saga University
The importance of the deletion of RP105 on B cells in autoimmune diseases and its application for the treatmentPrincipal Investigator
- Principal Investigator
  
  NAGASAWA Kohei
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Saga University
Role of inducible costimulator (ICOS) in the development of an autoimmune disease
- Principal Investigator
  
  TADA Yoshifumi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Saga University
  佐賀医科大学
Immunological Regulation of auto-reactive RP105-negative B cells
- Principal Investigator
  
  KOARADA Syuichi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Saga University
  佐賀医科大学
成人発症スティル病の診断・治療・予後に関する集学的研究
- Principal Investigator
  
  江口勝美
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  Nagasaki University
Analysis of pathogen recognition by TLR4 and RP105 and their application to immunothrapy
- Principal Investigator
  
  KIMOTO Masao
- Project Period (FY)
  2001 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  Saga University
  佐賀医科大学
Analysis of RP105 in association with the B cell activation in autoimmune diseasesPrincipal Investigator
- Principal Investigator
  
  NAGASAWA Kohei
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  Saga Medical School
Analysis of RP105, a novel B cell-associated antigen, in autoimmune diseasesPrincipal Investigator
- Principal Investigator
  
  NAGASAWA Kohei
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  Saga Medical School
Significance of infection with HTLV-1 as a pathogenesis of Sjogren's syndromePrincipal Investigator
- Principal Investigator
  
  NAGASAWA Kohei
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  Saga Medical School
Association of the functional impairement of T cells from patients with systemic lupus erythematosus with protein phosphorylationPrincipal Investigator
- Principal Investigator
  
  NAGASAWA Kohei
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  Saga Medical School
  Kyushu University
Intracellular regulation in the induction of differentiation in human malignant T lymphocytes.Principal Investigator
- Principal Investigator
  
  NAGASAWA Kohei
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Legal medicine
- Research Institution
  Kyushu University
Studies on factors related to pathogenesis and symptoms of systemic lupus erythematosus.
- Principal Investigator
  
  KUSABA Tomohiro
- Project Period (FY)
  1985 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  Kyushu University

All 2010 2009 2008 2007 2006 2005 2004

All Journal Article Presentation Book

[Book] リウマチ基本テキスト2005
- Author(s)
  長澤浩平
- Total Pages
  8
- Publisher
  日本リウマチ財団
- Data Source
  KAKENHI-PROJECT-16590985
[Book] リウマチ・膠原病診療チェックリスト2004
- Author(s)
  長澤浩平
- Total Pages
  7
- Publisher
  分光堂
- Data Source
  KAKENHI-PROJECT-16590985
[Book] 自然免疫と疾患2004
- Author(s)
  小荒田秀一, 長澤浩平
- Total Pages
  124
- Publisher
  医歯薬出版
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591057
[Journal Article] Effect of disease activity and corticosteroids on serum levels of soluble endothelial cell protein C receptor in patients with systemic lupus erythematosus.2009
- Author(s)
  Koarada S, Tsuneyoshi N, Haruta Y, Tada Y, Mitamura M, Inoue H, Ohta A, Fukudome K, Nagasawa K.
- Journal Title
  
  Mod Rheumatol 19
  
  Pages : 173-179
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591170
[Journal Article] Fujimoto K. Reflux esophagitis and helicobacter pylori infection in patients with scleroderma2008
- Author(s)
  Yamaguchi K, Iwakiri R, Hara M, Kikkawa A, Fujise T, Ootani H, Shimoda R, Tsunada S, Sakata H, Ushiyama O, Koarada S, Tada Y, Nagasawa K
- Journal Title
  
  Inter Med 47
  
  Pages : 1555-1559
- Data Source
  KAKENHI-PROJECT-19591170
[Journal Article] TNF阻害剤薬とメモリーB細胞機能2008
- Author(s)
  小荒田秀一, 長澤浩平
- Journal Title
  
  リウマチ科 40
  
  Pages : 190-195
- Data Source
  KAKENHI-PROJECT-19591170
[Journal Article] Toll-like receptor homolog RP105 modulates the antigen-presenting cell function and regulates the development of collagen-induced arthritis2008
- Author(s)
  Tada Y, Koarada S, Morito F, Mitamura M, Inoue H, Suematsu R, Ohta A, Miyake K, Nagasawa K
- Journal Title
  
  Arthritis Res Ther 10
- Data Source
  KAKENHI-PROJECT-19591170
[Journal Article] Nocardiosis in adult-onset Still's disease and vasculitis syndrome2008
- Author(s)
  Tada Y, Fukuoka M, Mitamura M, Koarada S, Suematsu R, Inoue H, Ohta A, Nagasawa K
- Journal Title
  
  Am J Med Sci 336
  
  Pages : 77-80
- Data Source
  KAKENHI-PROJECT-19591170
[Journal Article] High-resolution computed tomography characterization of interstitial lung diseases in polymypositis /dermatomyositis2008
- Author(s)
  Hayashi S, Tanaka M, Kobayashi H, Nakazono T, Satoh T, Fukuno Y, Aragane N, Tada Y, Koarada S, Ohta A, Nagasawa K
- Journal Title
  
  J Rheumatol 35
  
  Pages : 260-269
- Data Source
  KAKENHI-PROJECT-19591170
[Journal Article] Increase of RP105-lacking activated B cells in the peripheral blood and salivary glands in patients with Sjogren's syndrome2008
- Author(s)
  Kikuchi Y, Koarada S, Nakamura S, Yonemitsu N, Tada Y, Haruta Y, Morito F, Ohta A, Miyake K, Horiuchi T, Nagasawa K
- Journal Title
  
  Clin Exp Rheumatol 26
  
  Pages : 5-12
- Data Source
  KAKENHI-PROJECT-19591170
[Journal Article] Toll-like receptor homolog RP105 modulates the antigen-presenting cell function and regulates the development of collagen-induced arthritis.2008
- Author(s)
  ada Y, Koarada S, Morito F, Mitamura M, Inoue H, Suematsu R, Ohta A, Miyake K, Nagasawa K.
- Journal Title
  
  Arthritis Res Ther 10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591170
[Journal Article] Increase of RP105-lacking activated B cells in the peripheral blood and salivary glands in patients with Sjogren's syndrome.2008
- Author(s)
  Kikuchi Y, Koarada S, Nakamura S, Yonemitsu N, Tada Y, Haruta Y, Morito F, Ohta A, Miyake K, Horiuchi T, Nagasawa K.
- Journal Title
  
  Clin Exp Rheumatol 26
  
  Pages : 5-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591170
[Journal Article] Increase of RP105-lacking activated B cells in the peripheral blood and salivary glands in patients with Sjogren's syndrome2008
- Author(s)
  Kikuchi Y, Koarada S, Nakamura S, Yonemitsu N, Tada Y, Haruta Y, Morito F, Ohta A, Miyake K, Horiuchi T, Nagasawa K
- Journal Title
  
  Clin Exp Rheumatol (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591115
[Journal Article] Effect of disease activity and corticosteroids on serum levels of soluble endothelial cell protein C receptor in patients with systemic lupus erythematosus2008
- Author(s)
  Koarada S, Tsuneyoshi N, Haruta Y, Tada Y, Mitamura M, Inoue H, Ohta A, Fukudome K, Nagasawa K
- Journal Title
  
  Mod Rheumatol(Epub ahead of print)
- Data Source
  KAKENHI-PROJECT-19591170
[Journal Article] Increase of RP105-lacking activated B cell in the peripheral blood and salivary glands in patients with Sjogren's syndrome2008
- Author(s)
  Kikuchi Y, Koarada S, Nakamura S, Yonemitsu N, Tada Y, Haruta Y, Morito F, Ohta A, Miyake K, Horiuchi T, Nagasawa K.
- Journal Title
  
  Clin Exp Rheumatol 26
  
  Pages : 5-12
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591115
[Journal Article] High-resolution computed tomography characterization of interstitial lung diseases in polymyositis/dermatomyositis2008
- Author(s)
  Hayashi S, Tanaka M, Kobayashi H, Nakazono T, Satoh T, Fukuno Y, Arakane N, Tada Y, Koarada S, Ohta A, Nagasawa K.
- Journal Title
  
  J Rheumatol 36
  
  Pages : 260-269
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591115
[Journal Article] Nocardiosis in adult onset Still's disease and vasculitis syndrome2008
- Author(s)
  Tada Y, Fukuoka M, Mitamura M, Koarada S, Suematsu R, Ohta A, Nagasawa K.
- Journal Title
  
  Am J Med Sci (印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591115
[Journal Article] High expression of Toll-like receptor 4 on CD14+ monocytes in acute infectious diseases2007
- Author(s)
  Haruta Y, Koarada S, Tada Y, Mitamura M, Ohta A, Fukuoka M, Hayashi S, Nagasawa Ka
- Journal Title
  
  Scand J Infect Dis 39(6-7)
  
  Pages : 577-83
- Data Source
  KAKENHI-PROJECT-19591170
[Journal Article] SLEの発症機序と新たな治療法の探索-SLEにおけるRP105陰性B細胞の意義2007
- Author(s)
  小荒田秀一, 長澤浩平
- Journal Title
  
  リウマチ科 (0915-227X)38
  
  Pages : 113-120
- Data Source
  KAKENHI-PROJECT-19591170
[Journal Article] High-Resolution Computed Tomography Characterization of Interstitial Lung Diseases in Polymyositis/Dermatomyositis2007
- Author(s)
  Hayashi S, Tanaka M, Kobayashi H, Nakazono T, Satoh T, Fukuno Y, Aragane N, Tada Y, Koarada S, Ohta A, Nagasawa K.
- Journal Title
  
  J Rheumatol. (Epub ahead of print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591170
[Journal Article] High expression of Toll-like receptor 4 on CD14+ monocytes in acute infectious diseases2007
- Author(s)
  Haruta Y, Koarada S, Tada Y, Mitamura M, Ohta A, Fukuoka M, Hayashi S, Nagasawa K.
- Journal Title
  
  Scand J Infect Dis. 36
  
  Pages : 577-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591170
[Journal Article] SLEにおけるRP105陰性B細胞の意義2007
- Author(s)
  小荒田秀一, 長澤浩平
- Journal Title
  
  リウマチ科 38
  
  Pages : 113-120
- Data Source
  KAKENHI-PROJECT-19591170
[Journal Article] A functional M196R polymorphism of tumour necrosis factor receptor type 2 is associated with systemic lupus erythematosus: a case-control study and a meta-analysis2007
- Author(s)
  Horiuchi T, Kiyohara C, Tsukamoto H, Sawabe T, Furugo I, Yoshizawa S, Ueda A, Tada Y, Kimoto Y, Mitoma H, Harashima S, Yoshizawa S, Shimoda T, Okamura S, Nagasawa K, Harada M.
- Journal Title
  
  Ann Rheum Dis 66
  
  Pages : 320-324
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591115
[Journal Article] High expression of Toll-like receptor 4 on CD14+ monocytes in a cute infectious diseases2007
- Author(s)
  Haruta Y, Koarada S, Tada Y, Mitamura M, Ohta A, Fukuoka M, Hayashi S and Nagasawa K.
- Journal Title
  
  Scand J Infect Dis 39
  
  Pages : 577-583
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591115
[Journal Article] High expression of Toll-like receptor 4 on CD14+ monocytes in a cute infectious diseases2007
- Author(s)
  Haruta Y, Koarada S, Tada Y, Mitamura M, Ohta A, Fukuoka M, Hayashi S, Nagasawa K.
- Journal Title
  
  Scand J Infect Dis 39
  
  Pages : 577-583
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591115
[Journal Article] A functional M196R polymorphism of tumour necrosis factor receptor type 2 is associated with systemic lupus erythematosus:a case-control study and a meta-analysis2007
- Author(s)
  Horiuchi T, Kiyohara C, Tsukamoto H, Sawabe T, Furugo I, Yoshizawa S, Ueda A, Tada Y, Kimoto Y, Mitoma H, Harashima S, Yoshizawa S, Shimoda T, Okamura S, Nagasawa K, Harada M.
- Journal Title
  
  Ann Rheum Dis 66
  
  Pages : 320-324
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591115
[Journal Article] Prevention of steroid-induced osteonecrosis of femoral head in systemic lupus erythematosus by anti-coagulant2006
- Author(s)
  Nagasawa K, et. al.
- Journal Title
  
  Lupus 15
  
  Pages : 354-357
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591115
[Journal Article] Ex vivo CD4+T cell cytokine expression from patients with Sjogren's syndrome following in vitro stimulation to induce proliferation.2006
- Author(s)
  Koarada S, Haruta Y, Mitamura M, Morito F, Tada Y, Ohta A, Nagasawa K.
- Journal Title
  
  Rheumatology 45
  
  Pages : 392-399
- Data Source
  KAKENHI-PROJECT-18591115
[Journal Article] Prevention of steroid-induced osteonecrosis of femoral head in systemic lupus erythematosus by anti-coagulant.2006
- Author(s)
  Nagasawa K, Tada Y, Koarada S, Tsukamoto H, Horiuchi T, et al.
- Journal Title
  
  Lupus 15
  
  Pages : 354-357
- Data Source
  KAKENHI-PROJECT-18591115
[Journal Article] The association of Behcet's disease with myelodysplastic syndrome in Japan : A review of the litei-ature.2006
- Author(s)
  Tada Y, Koarada S, Haruta Y, Mitamura M, Ohta A, Nagasawa K.
- Journal Title
  
  Clin Exp Rheumatol 24(Suppl.42)
  
  Pages : 115-119
- Data Source
  KAKENHI-PROJECT-18591115
[Journal Article] Prevention of steroid-induced osteonecrosis of femoral head in systemic lupus erythematosus by anti-coagulant.2006
- Author(s)
  Nagasawa K, Tada Y, Koarada S, Tsukamoto. H, Horiuchi T, et al.
- Journal Title
  
  Lupus (In press)
- Data Source
  KAKENHI-PROJECT-16590985
[Journal Article] Development of microscopic polyangitis in patients with chronic airway disease.2005
- Author(s)
  Takahashi K, Hayashi S, Ushiyama O, Sueoka N, Fukuoka M, Nagasawa K.
- Journal Title
  
  Lung 183
  
  Pages : 273-281
- Data Source
  KAKENHI-PROJECT-16590985
[Journal Article] Very early development of steroid-associated osteonecrosis of femoral head in systemic lupus erythematosus. Prospective study by MRI.2005
- Author(s)
  Nagasawa K, Tada Y, Koarada S, Horiuchi T, Tsukamoto H, et al.
- Journal Title
  
  Lupus 14
  
  Pages : 385-390
- Data Source
  KAKENHI-PROJECT-16590985
[Journal Article] Very early development of steroid-associated osteonecrosis of femoral head in systemic lupus erythematosus.2005
- Author(s)
  Nagasawa K, Tada Y, Koarada S, Horiuchi T, Tsukamoto H, et al.
- Journal Title
  
  Lupus 14
  
  Pages : 385-390
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590985
[Journal Article] Very early development of steroid-associated osteonecrosis of femoral head in systemic lupus erythematosus.2005
- Author(s)
  Nagasawa K, Tada Y, Koarada S, Horiuchi T, Tsukamoto H, et al.
- Journal Title
  
  Lupus (In press)
- Data Source
  KAKENHI-PROJECT-16590985
[Journal Article] Very early development of steroid-associated osteonecrosis of femoral head in systemic lupus erythematosus.2005
- Author(s)
  Nagasawa, K.et al.
- Journal Title
  
  Lupus 14
  
  Pages : 385-390
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590985
[Journal Article] SLEにおけるRP105陰性B細胞の役割2004
- Author(s)
  長澤浩平
- Journal Title
  
  臨床免疫 41
  
  Pages : 696-700
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590985
[Journal Article] The role of RP105-lacking B cells in SLE.2004
- Author(s)
  Nagasawa, K.
- Journal Title
  
  Clinical Immunology 41
  
  Pages : 696-700
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590985
[Presentation] IRF5はループスマウスの病態発現に重要な役割をはたす2010
- Author(s)
  多田芳史、近藤誠司、小荒田秀一、長澤浩平
- Organizer
  第30回福岡臨床免疫研究会
- Place of Presentation
  福岡
- Year and Date
  2010-01-23
- Data Source
  KAKENHI-PROJECT-22590893
[Presentation] Toll-like receptor homolog RP105 attenuates the development of collagen-induced arthritis2008
- Author(s)
  Tada Y, Koarada S, Ohta A, Nagasawa K
- Organizer
  American College of Rheumatology Scientific Meeting(米国リウマチ学会議)
- Place of Presentation
  サンフランシスコ
- Data Source
  KAKENHI-PROJECT-19591170
[Presentation] シェーグレン症候群における末梢血および唾液腺組織におけるRP105陰性B細胞の解析2008
- Author(s)
  小荒田秀一, 菊池裕治, 多田芳史, 中村誠司, 米満伸久, 春田善男, 末松梨絵, 三田村未央, 井上久子, 大田明英, 堀内孝彦, 長澤浩平
- Organizer
  第17回日本シェーグレン症候群研究会(第17回日本シェーグレン症候群研究会プログラム抄録集)(72)
- Place of Presentation
  岐阜
- Data Source
  KAKENHI-PROJECT-19591170
[Presentation] セロトニン受容体拮抗剤塩酸サルポグレラートのレイノー現象および血小板活性化に対する効果(407)2008
- Author(s)
  多田芳史, 末松梨絵, 三田村未央, 井上久子, 小荒田秀一, 大田明英, 長澤浩平
- Organizer
  第52回日本リウマチ学会総会・学術集会・第17回国際リウマチシンポジウム(第52回日本リウマチ学会総会・学術集会・第17回国際リウマチシンポジウムプログラム・抄録集)
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-19591170
[Presentation] 全身性エリテマトーデス(SLE)における自己抗体産生RP105陰性B細胞のフェノタイプ解析(31:302)2008
- Author(s)
  小荒田秀一, 多田芳史, 末松梨絵, 井上久子, 三田村未央, 大田明英, 長澤浩平
- Organizer
  第36回日本臨床免疫学会総会(日本臨床免疫学会会誌)
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19591170
[Presentation] 関節リウマチにおけるCD4+T細胞のサイトカイン産生能と治療反応性予測(503)2008
- Author(s)
  小荒田秀一, 多田芳史, 末松梨絵, 三田村未央, 井上久子, 大田明英, 長澤浩平
- Organizer
  第52回日本リウマチ学会総会・学術集会・第17回国際リウマチシンポジウム(第52回日本リウマチ学会総会・学術集会第17回国際リウマチシンポジウムプログラム・抄録集)
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-19591170
[Presentation] 抗セントロメア抗体陽性シェーグレン症候群についての検討(282)2008
- Author(s)
  井上久子, 末松梨絵, 三田村未央, 小荒田秀一, 多田芳史, 大田明英, 長澤浩平
- Organizer
  第52回日本リウマチ学会総会・学術集会・第17回国際リウマチシンポジウム(第52回日本リウマチ学会総会・学術集会・第17回国際リウマチシンポジウムプログラム・抄録集)
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-19591170
[Presentation] 全身性エリテマトーデス(SLE)における自己抗体産生RP105陰性B細胞の臨床的意義(97:216)2008
- Author(s)
  小荒田秀一, 多田芳史, 末松梨絵, 三田村未央, 井上久子, 大田明英, 長澤浩平
- Organizer
  第105回日本内科学会総会(日本内科学会雑誌)
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19591170
[Presentation] 強皮症患者におけるストレス適応についての基礎的研究(407:2)2008
- Author(s)
  松浦江美, 大田明英, 末松梨絵, 三田村未央, 井上久子, 小荒田秀一, 多田芳史, 長澤浩平
- Organizer
  第52回日本リウマチ学会総会・学術集会・第17回国際リウマチシンポジウム(第52回日本リウマチ学会総会・学術集会・第17回国際リウマチシンポジウムプログラム・抄録集)
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-19591170
[Presentation] 抗セントロメア抗体陽性シェーグレン症候群についての検討~抗SS-A抗体陽性群と陰性群の比較2008
- Author(s)
  井上久子, 多田芳史, 小荒田秀一, 三田村未央, 末松梨絵, 大田明英, 長澤浩平
- Organizer
  第17回日本シェーグレン症候群研究会(第17回日本シェーグレン症候群研究会プログラム抄録集)(89)
- Place of Presentation
  岐阜
- Data Source
  KAKENHI-PROJECT-19591170
[Presentation] サイトメガロウイルス(CMV)抗原血症を呈した膠原病患者の臨床的検討(329)2008
- Author(s)
  末松梨絵, 多田芳史, 三田村未央, 井上久子, 小荒田秀一, 大田明英, 長澤浩平
- Organizer
  第52回日本リウマチ学会総会・学術集会・第17回国際リウマチシンポジウム(第52回日本リウマチ学会総会・学術集会・第17回国際リウマチシンポジウムプログラム・抄録集)
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-19591170
[Presentation] 成人スチル病患者におけるガリウムシンチグラフィー所見の検討(421)2008
- Author(s)
  三田村未央, 末松梨絵, 井上久子, 小荒田秀一, 多田芳史, 大田明英, 鐘江大, 長澤浩平
- Organizer
  第52回日本リウマチ学会総会・学術集会・第17回国際リウマチシンポジウム(第52回日本リウマチ学会総会・学術集会・第17回国際リウマチシンポジウムプログラム・抄録集)
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-19591170
[Presentation] サイトカイン解析と抗TNFα製剤の有効性との関連に関する検討(40)2008
- Author(s)
  小荒田秀一, 多田芳史, 末松梨絵, 三田村未央, 井上久子, 大田明英, 長澤浩平
- Organizer
  第36回九州リウマチ学会関節リウマチにおける生物製剤治療前のin vitro(第36回九州リウマチ学会プログラム抄録集)
- Place of Presentation
  佐賀
- Data Source
  KAKENHI-PROJECT-19591170
[Presentation] 第105回日本内科学会総会全身性エリテマトーデス(SLE)における自己抗体産生RP105陰性B細胞の臨床的意義2008
- Author(s)
  小荒田秀一, 多田芳史, 末松梨絵, 三田村未央, 井上久子, 大田明英, 長澤浩平
- Organizer
  日本内科学会雑誌97:216.
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19591170
[Presentation] SLE-Up to Date-(特別講演)2007
- Author(s)
  長澤浩平
- Organizer
  第33回九州リウマチ学会
- Place of Presentation
  大分市
- Year and Date
  2007-03-10
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591115
[Presentation] 大腿骨骨頭壊死の病態と治療.スタチン(シンポジウム)2007
- Author(s)
  長澤浩平
- Organizer
  第80回日本整形外科学会学術総会
- Place of Presentation
  神戸市
- Year and Date
  2007-05-27
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591115
[Presentation] SLEにおけるステロイド投与が血管内皮機能に与える影響-ステロイド投与による可溶型内皮プロテインC受容体(sEPCR)の変動に関する検討(256)2007
- Author(s)
  小荒田秀一, 末松梨絵, 三田村未央, 井上久子, 多田芳史, 大田明英, 長澤浩平
- Organizer
  第51回日本リウマチ学会総会・学術集会, 第16回国際リウマチシンポジウム(第51回日本リウマチ学会総会・学術集会, 第16回国際リウマチシンポジウムプログラム集)
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19591170
[Presentation] RP105分子のコラーゲン関節炎における作用の解析(381)2007
- Author(s)
  多田芳史, 小荒田秀一, 三田村未央, 井上久子, 末松梨絵, 大田明英, 長澤浩平
- Organizer
  第51回日本リウマチ学会総会・学術集会, 第16回国際リウマチシンポジウム(第51回日本リウマチ学会総会・学術集会, 第16回国際リウマチシンポジウムプログラム集)
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19591170
[Presentation] ワルファリンとスタチンによるステロイド性大腿骨頭壊死の予防研究(7)2007
- Author(s)
  長澤浩平, 小荒田秀一, 堀内孝彦, 末松栄一
- Organizer
  厚生労働科学研究費補助金難治性疾患克服研究事業平成19年度第一回班会議研究成果報告会(平成19年度第一回班会議研究成果報告会プログラム集)
- Place of Presentation
  京都
- Year and Date
  2007-07-07
- Data Source
  KAKENHI-PROJECT-19591170
[Presentation] 成人スチル病(AOSD)30例の治療についての検討 : 特にシクロスポリンA(CyA)の有効性について(336)2007
- Author(s)
  三田村未央, 末松梨絵, 井上久子, 小荒田秀一, 多田芳史, 大田明英, 長澤浩平, 鐘江大
- Organizer
  第51回日本リウマチ学会総会・学術集会, 第16回国際リウマチシンポジウム(第51回日本リウマチ学会総会・学術集会, 第16回国際リウマチシンポジウムプログラム集)
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19591170
[Presentation] 自己免疫疾患における自己抗体産生B細胞を標的とした治療の開発2007
- Author(s)
  長澤浩平, 小荒田秀一
- Organizer
  厚生労働省免疫アレルギー疾患予防・治療事業,免疫疾患に対する免疫抑制療法等先端的新規治療に関する研究
- Place of Presentation
  東京
- Year and Date
  2007-12-06
- Data Source
  KAKENHI-PROJECT-19591170
[Presentation] Toll-likeレセプターホモグログRP105はコラーゲン関節炎の発症を抑制する(133)2007
- Author(s)
  多田芳史, 小荒田秀一, 大田明英, 長澤浩平
- Organizer
  第37回日本免疫学会総会・学術集会(第37回日本免疫学会総会・学術集会抄録集)
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19591170
[Presentation] SLEにおけるCD4+T細胞の細胞分裂とTh1/Th2サイトカインバランスの関係の検討(30:318)2007
- Author(s)
  小荒田秀一, 三田村未央, 末松梨絵, 井上久子, 多田芳史, 大田明英, 長澤浩平
- Organizer
  第30回日本臨床免疫学会(日本臨床免疫学会会誌)
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19591170
[Presentation] Anti-fibrotic effects of hepatocyte growth factor on scleroderma fibroblasts and analysis of its mechanism2007
- Author(s)
  Tadano RS, Ohta A, Morito F, Mitamura M, Haruta Y, Koarada S, Tada Y, Nagasawa K
- Organizer
  Professor Leroy EC Memorial International Workshop on Scleroderma
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-19591170
[Presentation] Pathophysiology and treatment of osteonecrosis of femoral Head. Statins.(Symposium)2007
- Author(s)
  Nagasawa, K
- Organizer
  The 80 th Annual Scientific Meeting of Japanese Society for Orthopedics
- Place of Presentation
  Kobe
- Year and Date
  2007-05-27
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591115
[Presentation] SLE-up to date -(Special Lecture)2007
- Author(s)
  Nagasawa, K
- Organizer
  The 33 rd Annual Scientific Meeting of Kyushu Rheumatology
- Place of Presentation
  Oita
- Year and Date
  2007-03-10
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591115
[Presentation] Toll-like レセプターホモグログRP105はコラーゲン関節炎の発症を抑制する2007
- Author(s)
  多田芳史, 小荒田秀一, 大田明英, 長澤浩平
- Organizer
  第37回日本免疫学会総会・
- Place of Presentation
  東京都
- Year and Date
  2007-11-20
- Data Source
  KAKENHI-PROJECT-18591115
[Presentation] SLEにおけるCD4+T細胞の細胞分裂とTh1/Th2サイトカインバランスの関係の検討2007
- Author(s)
  小荒田秀一, 三田村未央, 末松梨絵, 井上久子, 多田芳史, 大田明英, 長澤浩平
- Organizer
  日本臨床免疫学会
- Place of Presentation
  大阪
- Year and Date
  2007-10-19
- Data Source
  KAKENHI-PROJECT-19591170

1. KOARADA Syuichi (50304887)

# of Collaborated Projects : 9results

# of Collaborated Products : 53results
2. TADA Yoshifumi (70284627)

# of Collaborated Projects : 9results

# of Collaborated Products : 48results
3. KIMOTO Masao (40153225)

# of Collaborated Projects : 3results

# of Collaborated Products : 2results
4. USHIYAMA Osamu (40253596)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
5. MIYAKE Kensuke (60229812)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
6. SUZUKI Noriaki (40244024)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
7. KUSABA Tomohiro (10091290)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
8. 江口勝美 (30128160)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
9. 竹内勤 (50179610)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
10. 佐々木毅 (50110656)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
11. 小池隆夫 (80146795)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
12. 宮坂信之 (30157622)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
13. 堀内孝彦 (90219212)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
14. 真弓武仁 (70219541)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
15. 上田良輝

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
16. 都留智巳

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
17. 岩橋徳二

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
18. IWAHASHI Tokuji

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
19. 山内保生

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
20. YAMAUCHI Yasuo

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
21. 山内保夫

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
22. 久志本孝一

# of Collaborated Projects : 1results

# of Collaborated Products : 0results

NAGASAWA Kohei 長澤 浩平

Research Projects

Research Products

Co-Researchers

Role of the interferon regulatory factor 5 in the development of lupus nephritis

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The development of new therapeutic approaches to autoantibody-producing RP105-negative B cells in autoimmune diseases

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Total analysis of RP105 molecule on B cells : Its function and application to treatment in autoimmune diseasesPrincipal Investigator

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The importance of the deletion of RP105 on B cells in autoimmune diseases and its application for the treatmentPrincipal Investigator

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Role of inducible costimulator (ICOS) in the development of an autoimmune disease

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Immunological Regulation of auto-reactive RP105-negative B cells

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成人発症スティル病の診断・治療・予後に関する集学的研究

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Analysis of pathogen recognition by TLR4 and RP105 and their application to immunothrapy

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Analysis of RP105 in association with the B cell activation in autoimmune diseasesPrincipal Investigator

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Analysis of RP105, a novel B cell-associated antigen, in autoimmune diseasesPrincipal Investigator

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Significance of infection with HTLV-1 as a pathogenesis of Sjogren's syndromePrincipal Investigator

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Association of the functional impairement of T cells from patients with systemic lupus erythematosus with protein phosphorylationPrincipal Investigator

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Intracellular regulation in the induction of differentiation in human malignant T lymphocytes.Principal Investigator

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NAGASAWA Kohei 長澤浩平